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2025-10-22 11:57:27, GGRNA : RefSeq release 232 (Sep, 2025)
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Results:
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LOCUS XR_593163 4994 bp RNA linear ROD 22-FEB-2024 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X3, misc_RNA. ACCESSION XR_593163 VERSION XR_593163.4 DBLINK BioProject: PRJNA1074393 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS XR_593162 4999 bp RNA linear ROD 22-FEB-2024 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X2, misc_RNA. ACCESSION XR_593162 VERSION XR_593162.4 DBLINK BioProject: PRJNA1074393 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS XR_593161 4779 bp RNA linear ROD 22-FEB-2024 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X1, misc_RNA. ACCESSION XR_593161 VERSION XR_593161.4 DBLINK BioProject: PRJNA1074393 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS NM_001427742 3675 bp mRNA linear ROD 09-APR-2024 DEFINITION Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), mRNA. ACCESSION NM_001427742 XM_234465 VERSION NM_001427742.1 KEYWORDS RefSeq; RefSeq Select. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence...
and Suo,X. TITLE Molecular cloning and protein characterization of swine 4-1BB JOURNAL Vet Immunol Immunopathol 153 (1-2), 35-44 (2013) PUBMED 23453329 REFERENCE 2 (bases 1 to 1043) AUTHORS Shi,Y., Hu,S., Song,Q., Yu,S., Zhou,X., Yin,J., Qin,L. and Qian,H. TITLE Gene silencing of 4-1BB by RNA interference inhibits acute rejection in rats with liver transplantation JOURNAL Biomed Res Int 2013, 192738 (2013) PUBMED 23484089 REMARK GeneRIF: gene silencing of 4-1BB by RNA interference inhibits the acute rejection in rats with liver transplantation. REFERENCE 3 (bases 1 to 1043) AUTHORS Zhang,J.,...
AUTHORS Tsujimoto,R., Yurube,T., Takeoka,Y., Kanda,Y., Miyazaki,K., Ohnishi,H., Kakiuchi,Y., Miyazaki,S., Zhang,Z., Takada,T., Kuroda,R. and Kakutani,K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2256) AUTHORS Cheng,H., Xu,B.,...
AUTHORS Tsujimoto,R., Yurube,T., Takeoka,Y., Kanda,Y., Miyazaki,K., Ohnishi,H., Kakiuchi,Y., Miyazaki,S., Zhang,Z., Takada,T., Kuroda,R. and Kakutani,K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2331) AUTHORS Cheng,H., Xu,B.,...
AUTHORS Tsujimoto,R., Yurube,T., Takeoka,Y., Kanda,Y., Miyazaki,K., Ohnishi,H., Kakiuchi,Y., Miyazaki,S., Zhang,Z., Takada,T., Kuroda,R. and Kakutani,K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2425) AUTHORS Cheng,H., Xu,B.,...
AUTHORS Tsujimoto,R., Yurube,T., Takeoka,Y., Kanda,Y., Miyazaki,K., Ohnishi,H., Kakiuchi,Y., Miyazaki,S., Zhang,Z., Takada,T., Kuroda,R. and Kakutani,K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2335) AUTHORS Cheng,H., Xu,B.,...
Splign:2.1.0" exon 329..644 /gene="Tmem167b" /gene_synonym="RGD1564454" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 644) AUTHORS Wendler F, Gillingham AK, Sinka R, Rosa-Ferreira C, Gordon DE, Franch-Marro X, Peden AA, Vincent JP and Munro S. TITLE A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway JOURNAL EMBO J 29 (2), 304-314 (2010) PUBMED 19942856...
of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 2498) AUTHORS Vidal,R.L., Fuentes,P., Valenzuela,J.I., Alvarado-Diaz,C.P., Ramirez,O.A., Kukuljan,M. and Couve,A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
and Suo,X. TITLE Molecular cloning and protein characterization of swine 4-1BB JOURNAL Vet Immunol Immunopathol 153 (1-2), 35-44 (2013) PUBMED 23453329 REFERENCE 2 (bases 1 to 1410) AUTHORS Shi,Y., Hu,S., Song,Q., Yu,S., Zhou,X., Yin,J., Qin,L. and Qian,H. TITLE Gene silencing of 4-1BB by RNA interference inhibits acute rejection in rats with liver transplantation JOURNAL Biomed Res Int 2013, 192738 (2013) PUBMED 23484089 REMARK GeneRIF: gene silencing of 4-1BB by RNA interference inhibits the acute rejection in rats with liver transplantation. REFERENCE 3 (bases 1 to 1410) AUTHORS Zhang,J.,...
of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4409) AUTHORS Vidal,R.L., Fuentes,P., Valenzuela,J.I., Alvarado-Diaz,C.P., Ramirez,O.A., Kukuljan,M. and Couve,A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
target in hypertension induced by chronic intermittent hypoxia JOURNAL Pharmacol Res 159, 104869 (2020) PUBMED 32416216 REFERENCE 4 (bases 1 to 2107) AUTHORS Drevytska,T., Gonchar,E., Okhai,I., Lynnyk,O., Mankovska,I., Klionsky,D. and Dosenko,V. TITLE The protective effect of Hif3a RNA interference and HIF-prolyl hydroxylase inhibition on cardiomyocytes under anoxia-reoxygenation JOURNAL Life Sci 202, 131-139 (2018) PUBMED 29660430 REMARK GeneRIF: Hif3a RNA interference and HIF-prolyl hydroxylase inhibition protect cardiomyocytes against anoxia-reoxygenation injury via the HIF signaling...
of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 2410) AUTHORS Vidal,R.L., Fuentes,P., Valenzuela,J.I., Alvarado-Diaz,C.P., Ramirez,O.A., Kukuljan,M. and Couve,A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4378) AUTHORS Vidal,R.L., Fuentes,P., Valenzuela,J.I., Alvarado-Diaz,C.P., Ramirez,O.A., Kukuljan,M. and Couve,A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
AUTHORS Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A. TITLE Defining the membrane proteome of NK cells JOURNAL J Mass Spectrom 45 (1), 1-25 (2010) PUBMED 19946888 REFERENCE 2 (bases 1 to 2099) AUTHORS Suga,K., Hattori,H., Saito,A. and Akagawa,K. TITLE RNA interference-mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles JOURNAL FEBS Lett 579 (20), 4226-4234 (2005) PUBMED 16081076 REFERENCE 3 (bases 1 to 2099) AUTHORS Peng,J., Huang,C.H., Short,M.K. and Jubinsky,P.T. TITLE Magmas gene structure and...
alignment:Splign:2.1.0" exon 662..954 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 954) AUTHORS Zhao,Y., Goto,M., Vaziri,N.D., Khazaeli,M., Liu,H., Farahanchi,N., Khanifar,E., Farzaneh,T., Haslett,P.A., Moradi,H. and Soundarapandian,M.M. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects...
alignment:Splign:2.1.0" exon 206..3756 /gene="Tmem167a" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 3756) AUTHORS Wendler,F., Gillingham,A.K., Sinka,R., Rosa-Ferreira,C., Gordon,D.E., Franch-Marro,X., Peden,A.A., Vincent,J.P. and Munro,S. TITLE A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway JOURNAL EMBO J 29 (2), 304-314 (2010) PUBMED 19942856...
alignment:Splign:2.1.0" exon 891..1779 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 1779) AUTHORS Zhao,Y., Goto,M., Vaziri,N.D., Khazaeli,M., Liu,H., Farahanchi,N., Khanifar,E., Farzaneh,T., Haslett,P.A., Moradi,H. and Soundarapandian,M.M. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3...
target in hypertension induced by chronic intermittent hypoxia JOURNAL Pharmacol Res 159, 104869 (2020) PUBMED 32416216 REFERENCE 4 (bases 1 to 2065) AUTHORS Drevytska,T., Gonchar,E., Okhai,I., Lynnyk,O., Mankovska,I., Klionsky,D. and Dosenko,V. TITLE The protective effect of Hif3a RNA interference and HIF-prolyl hydroxylase inhibition on cardiomyocytes under anoxia-reoxygenation JOURNAL Life Sci 202, 131-139 (2018) PUBMED 29660430 REMARK GeneRIF: Hif3a RNA interference and HIF-prolyl hydroxylase inhibition protect cardiomyocytes against anoxia-reoxygenation injury via the HIF signaling...
curated by NCBI staff. The reference sequence was derived from JAXUCZ015.1 and FM038730.1. On Sep 18, 2014 this sequence version replaced NM_001191765.1. Summary: This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene...
Rattus. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JAXUCZ015.1 and FM038730.1. Summary: This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene...
of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4397) AUTHORS Vidal,R.L., Fuentes,P., Valenzuela,J.I., Alvarado-Diaz,C.P., Ramirez,O.A., Kukuljan,M. and Couve,A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
alignment:Splign:2.1.0" exon 1254..1620 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 1620) AUTHORS Zhao,Y., Goto,M., Vaziri,N.D., Khazaeli,M., Liu,H., Farahanchi,N., Khanifar,E., Farzaneh,T., Haslett,P.A., Moradi,H. and Soundarapandian,M.M. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3...
of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4366) AUTHORS Vidal,R.L., Fuentes,P., Valenzuela,J.I., Alvarado-Diaz,C.P., Ramirez,O.A., Kukuljan,M. and Couve,A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1 JOURNAL Development 139 (7), 1276-1284 (2012) PUBMED 22357932 REFERENCE 2 (bases 1 to 738) AUTHORS Vidigal,J.A., Morkel,M., Wittler,L., Brouwer-Lehmitz,A., Grote,P., Macura,K. and Herrmann,B.G. TITLE An inducible RNA interference system for the functional dissection of mouse embryogenesis JOURNAL Nucleic Acids Res 38 (11), e122 (2010) PUBMED 20350929 REFERENCE 3 (bases 1 to 738) AUTHORS Zizic Mitrecic,M., Mitrecic,D., Pochet,R., Kostovic-Knezevic,L. and Gajovic,S. TITLE The mouse gene Noto is expressed in the tail...
PUBMED 31549412 REMARK GeneRIF: miR-218 regulates diabetic nephropathy via targeting IKK-beta and modulating NK-kappaB-mediated inflammation. REFERENCE 4 (bases 1 to 3525) AUTHORS Wei,S.F., Sun,J.J., Zhou,N., Li,X.L., Lin,Y., Zhang,Y.D., Zhang,Y.R. and Wu,L.Y. TITLE Protective effect of RNA interference targeting Ikkbeta on hepatic fibrosis in rats JOURNAL J Cell Biochem 120 (11), 18894-18900 (2019) PUBMED 31297885 REMARK GeneRIF: Protective effect of RNA interference targeting Ikkbeta on hepatic fibrosis in rats. REFERENCE 5 (bases 1 to 3525) AUTHORS Dondelinger,Y., Delanghe,T., Priem,D.,...
to influenza A H1N1 virus, West Nile virus, and dengue virus JOURNAL Cell 139 (7), 1243-1254 (2009) PUBMED 20064371 REFERENCE 8 (bases 1 to 672) AUTHORS Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J. TITLE Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos JOURNAL Development 132 (11), 2599-2609 (2005) PUBMED 15857914...
AUTHORS Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A. TITLE Defining the membrane proteome of NK cells JOURNAL J Mass Spectrom 45 (1), 1-25 (2010) PUBMED 19946888 REFERENCE 4 (bases 1 to 2726) AUTHORS Suga,K., Hattori,H., Saito,A. and Akagawa,K. TITLE RNA interference-mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles JOURNAL FEBS Lett 579 (20), 4226-4234 (2005) PUBMED 16081076 REFERENCE 5 (bases 1 to 2726) AUTHORS Loh,E., Peter,F., Subramaniam,V.N. and Hong,W. TITLE Mammalian Bet3 functions as a...
regulate self-renewal in embryonic stem cells JOURNAL Genes Dev 21 (20), 2545-2557 (2007) PUBMED 17938240 REFERENCE 3 (bases 1 to 1324) AUTHORS Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, DeCoste C, Schafer X, Lun Y and Lemischka IR. TITLE Dissecting self-renewal in stem cells with RNA interference JOURNAL Nature 442 (7102), 533-538 (2006) PUBMED 16767105 REFERENCE 4 (bases 1 to 1324) AUTHORS Narducci MG, Fiorenza MT, Kang SM, Bevilacqua A, Di Giacomo M, Remotti D, Picchio MC, Fidanza V, Cooper MD, Croce CM, Mangia F and Russo G. TITLE TCL1 participates in early embryonic development and...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1032..1394 /gene="Ago4" /gene_synonym="Eif2c4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1188..1190,1233..1235,1275..1277,1287..1289, 1341..1343,1362..1364,1368..1370) /gene="Ago4" /gene_synonym="Eif2c4" /note="nucleic acid...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 933..1295 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1089..1091,1134..1136,1176..1178,1188..1190, 1242..1244,1263..1265,1269..1271) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-...
Mai,Z., Peng,Z., Yu,K., Liu,G. and Ai,H. TITLE Cyclical compressive stress induces differentiation of rat primary mandibular condylar chondrocytes through phosphorylated myosin light chain II JOURNAL Mol Med Rep 14 (5), 4293-4300 (2016) PUBMED 27748856 REMARK GeneRIF: Silencing MLCII by RNA interference reduced ALP activity (P<0.01), and eliminated RUNX2 mRNA expression (P<0.01). Addition of the MLC kinase inhibitor, ML7, reduced the CUCSassociated upregulation of RUNX2 expression (P<0.01) and ALP activity (P<0.01). REFERENCE 4 (bases 1 to 677) AUTHORS Wijnker,P.J., Li,Y., Zhang,P., Foster,D.B...
misc_feature 177..518 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(312..314,357..359,399..401,411..413,465..467, 486..488,492..494) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
misc_feature 174..515 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(309..311,354..356,396..398,408..410,462..464, 483..485,489..491) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
exon 315..617 /gene="Rpa3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 617) AUTHORS McJunkin,K., Mazurek,A., Premsrirut,P.K., Zuber,J., Dow,L.E., Simon,J., Stillman,B. and Lowe,S.W. TITLE Reversible suppression of an essential gene in adult mice using transgenic RNA interference JOURNAL Proc Natl Acad Sci U S A 108 (17), 7113-7118 (2011) PUBMED 21482754 REFERENCE 2 (bases 1 to 617) AUTHORS Sakaguchi,K., Ishibashi,T., Uchiyama,Y. and Iwabata,K. TITLE The multi-replication protein A (RPA) system--a new perspective JOURNAL FEBS J 276 (4), 943-963 (2009) PUBMED 19154342...
PUBMED 16371587 REFERENCE 4 (bases 1 to 2316) AUTHORS Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E., Fan,J.B., Abraham,R.T. and Jiang,W. TITLE Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005) PUBMED 15843429 REFERENCE 5 (bases 1 to 2316) AUTHORS Yang,W.X. and Sperry,A.O. TITLE C-terminal kinesin motor KIFC1 participates in acrosome biogenesis and vesicle transport JOURNAL Biol Reprod 69 (5), 1719-1729 (2003) PUBMED 12826589 REMARK GeneRIF: KIFC1,...
PUBMED 18485706 REFERENCE 3 (bases 1 to 2098) AUTHORS Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E., Fan,J.B., Abraham,R.T. and Jiang,W. TITLE Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005) PUBMED 15843429 REFERENCE 4 (bases 1 to 2098) AUTHORS Dickins,R.A., Frew,I.J., House,C.M., O'Bryan,M.K., Holloway,A.J., Haviv,I., Traficante,N., de Kretser,D.M. and Bowtell,D.D. TITLE The ubiquitin ligase component Siah1a is required for completion of meiosis...
misc_feature 6283..6624 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(6418..6420,6463..6465,6505..6507,6517..6519, 6571..6573,6592..6594,6598..6600) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
misc_feature 6319..6660 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(6454..6456,6499..6501,6541..6543,6553..6555, 6607..6609,6628..6630,6634..6636) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
markedly during pathogenesis of pulmonary arterial hypertension (PAH), indicating that CF6 may be involved in the development of PAH REFERENCE 3 (bases 1 to 571) AUTHORS Yin,J., You,S., Li,N., Jiao,S., Hu,H., Xue,M., Wang,Y., Cheng,W., Liu,J., Xu,M., Yan,S. and Li,X. TITLE Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats JOURNAL Respir Res 17 (1), 99 (2016) PUBMED 27491388 REMARK GeneRIF: CF6 shRNA effectively inhibited CF6 expression, abolished lung macrophage infiltration, reversed endothelial dysfunction and vascular...
genome-wide screens of intracellular proteolytic cleavage JOURNAL Genome Biol 9 (4), R64 (2008) PUBMED 18387192 REMARK Publication Status: Online-Only REFERENCE 5 (bases 1 to 2888) AUTHORS Yoshimura,K., Shibata,M., Koike,M., Gotoh,K., Fukaya,M., Watanabe,M. and Uchiyama,Y. TITLE Effects of RNA interference of Atg4B on the limited proteolysis of LC3 in PC12 cells and expression of Atg4B in various rat tissues JOURNAL Autophagy 2 (3), 200-208 (2006) PUBMED 16874114 REFERENCE 6 (bases 1 to 2888) AUTHORS Tanida,I., Ueno,T. and Kominami,E. TITLE LC3 conjugation system in mammalian autophagy JOURNAL...
PUBMED 26884831 REMARK GeneRIF: Sdit2 may play a vital role in the regulation of insulin secretion via two SNARE proteins synap1 and syanp3. Publication Status: Online-Only REFERENCE 5 (bases 1 to 4159) AUTHORS Li,W., Koutmou,K.S., Leahy,D.J. and Li,M. TITLE Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1 JOURNAL J Biol Chem 290 (31), 18904-18913 (2015) PUBMED 26067272 REFERENCE 6 (bases 1 to 4159) AUTHORS Gao,J., Gu,X., Mahuran,D.J., Wang,Z. and Zhang,H. TITLE Impaired glucose tolerance...
markedly during pathogenesis of pulmonary arterial hypertension (PAH), indicating that CF6 may be involved in the development of PAH REFERENCE 3 (bases 1 to 614) AUTHORS Yin,J., You,S., Li,N., Jiao,S., Hu,H., Xue,M., Wang,Y., Cheng,W., Liu,J., Xu,M., Yan,S. and Li,X. TITLE Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats JOURNAL Respir Res 17 (1), 99 (2016) PUBMED 27491388 REMARK GeneRIF: CF6 shRNA effectively inhibited CF6 expression, abolished lung macrophage infiltration, reversed endothelial dysfunction and vascular...
PUBMED 26884831 REMARK GeneRIF: Sdit2 may play a vital role in the regulation of insulin secretion via two SNARE proteins synap1 and syanp3. Publication Status: Online-Only REFERENCE 5 (bases 1 to 4222) AUTHORS Li,W., Koutmou,K.S., Leahy,D.J. and Li,M. TITLE Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1 JOURNAL J Biol Chem 290 (31), 18904-18913 (2015) PUBMED 26067272 REFERENCE 6 (bases 1 to 4222) AUTHORS Gao,J., Gu,X., Mahuran,D.J., Wang,Z. and Zhang,H. TITLE Impaired glucose tolerance...
PUBMED 26884831 REMARK GeneRIF: Sdit2 may play a vital role in the regulation of insulin secretion via two SNARE proteins synap1 and syanp3. Publication Status: Online-Only REFERENCE 5 (bases 1 to 4621) AUTHORS Li,W., Koutmou,K.S., Leahy,D.J. and Li,M. TITLE Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1 JOURNAL J Biol Chem 290 (31), 18904-18913 (2015) PUBMED 26067272 REFERENCE 6 (bases 1 to 4621) AUTHORS Gao,J., Gu,X., Mahuran,D.J., Wang,Z. and Zhang,H. TITLE Impaired glucose tolerance...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 374..736 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(530..532,575..577,617..619,629..631,683..685, 704..706,710..712) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 381..743 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(537..539,582..584,624..626,636..638,690..692, 711..713,717..719) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding...
markedly during pathogenesis of pulmonary arterial hypertension (PAH), indicating that CF6 may be involved in the development of PAH REFERENCE 3 (bases 1 to 756) AUTHORS Yin,J., You,S., Li,N., Jiao,S., Hu,H., Xue,M., Wang,Y., Cheng,W., Liu,J., Xu,M., Yan,S. and Li,X. TITLE Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats JOURNAL Respir Res 17 (1), 99 (2016) PUBMED 27491388 REMARK GeneRIF: CF6 shRNA effectively inhibited CF6 expression, abolished lung macrophage infiltration, reversed endothelial dysfunction and vascular...
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Redirect URI : https://ggrna.dbcls.jp/ja/rn/%22RNA+interference%22
lang : ja |
div : |
spe : rn |
query_string : "RNA interference" |
format : html |
download :
0.000 | 0.000 | search_start;
0.083 | 0.083 | count_done; http://172.18.8.71:7700/v1/refsub/query?q=((full_search:*:RNA+interference)%7C(nt:RNA+interference)%7C(aa:RNA+interference))?source=Rattus norvegicus (Norway rat)?to=0&format=json
0.155 | 0.071 | search_done; http://172.18.8.71:7700/v1/refsub/query?q=((full_search:*:RNA+interference)%7C(nt:RNA+interference)%7C(aa:RNA+interference))?source=Rattus norvegicus (Norway rat)?to=49?from=0?snippet=full_search?drilldown=source?get=accession,version,gi,length,symbol,synonym,geneid,division,source,definition&format=json
0.160 | 0.005 | cgi_end;
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GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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