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Previous release (v1)
2026-10-15 05:20:11, GGRNA : RefSeq release 233 (Jan, 2026)
Summary:
Results:
Matches are highlighted with green background.
Overlapping matches are dark colored.
LOCUS XR_593163 4994 bp RNA linear ROD 22-FEB-2024 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X3, misc_RNA. ACCESSION XR_593163 VERSION XR_593163.4 DBLINK BioProject: PRJNA1074393 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS XR_593162 4999 bp RNA linear ROD 22-FEB-2024 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X2, misc_RNA. ACCESSION XR_593162 VERSION XR_593162.4 DBLINK BioProject: PRJNA1074393 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS XR_593161 4779 bp RNA linear ROD 22-FEB-2024 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X1, misc_RNA. ACCESSION XR_593161 VERSION XR_593161.4 DBLINK BioProject: PRJNA1074393 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS NM_001427742 3675 bp mRNA linear ROD 09-APR-2024 DEFINITION Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), mRNA. ACCESSION NM_001427742 XM_234465 VERSION NM_001427742.1 KEYWORDS RefSeq; RefSeq Select. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence...
Splign:2.1.0" exon 329..644 /gene="Tmem167b" /gene_synonym="RGD1564454" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 644) AUTHORS Wendler F, Gillingham AK, Sinka R, Rosa-Ferreira C, Gordon DE, Franch-Marro X, Peden AA, Vincent JP and Munro S. TITLE A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway JOURNAL EMBO J 29 (2), 304-314 (2010) PUBMED 19942856...
alignment:Splign:2.1.0" exon 662..954 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 954) AUTHORS Zhao,Y., Goto,M., Vaziri,N.D., Khazaeli,M., Liu,H., Farahanchi,N., Khanifar,E., Farzaneh,T., Haslett,P.A., Moradi,H. and Soundarapandian,M.M. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects...
alignment:Splign:2.1.0" exon 206..3756 /gene="Tmem167a" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 3756) AUTHORS Wendler,F., Gillingham,A.K., Sinka,R., Rosa-Ferreira,C., Gordon,D.E., Franch-Marro,X., Peden,A.A., Vincent,J.P. and Munro,S. TITLE A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway JOURNAL EMBO J 29 (2), 304-314 (2010) PUBMED 19942856...
alignment:Splign:2.1.0" exon 891..1779 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 1779) AUTHORS Zhao,Y., Goto,M., Vaziri,N.D., Khazaeli,M., Liu,H., Farahanchi,N., Khanifar,E., Farzaneh,T., Haslett,P.A., Moradi,H. and Soundarapandian,M.M. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3...
curated by NCBI staff. The reference sequence was derived from JAXUCZ015.1 and FM038730.1. On Sep 18, 2014 this sequence version replaced NM_001191765.1. Summary: This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene...
Rattus. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JAXUCZ015.1 and FM038730.1. Summary: This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene...
alignment:Splign:2.1.0" exon 1254..1620 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 1620) AUTHORS Zhao,Y., Goto,M., Vaziri,N.D., Khazaeli,M., Liu,H., Farahanchi,N., Khanifar,E., Farzaneh,T., Haslett,P.A., Moradi,H. and Soundarapandian,M.M. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3...
to influenza A H1N1 virus, West Nile virus, and dengue virus JOURNAL Cell 139 (7), 1243-1254 (2009) PUBMED 20064371 REFERENCE 8 (bases 1 to 672) AUTHORS Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J. TITLE Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos JOURNAL Development 132 (11), 2599-2609 (2005) PUBMED 15857914...
regulate self-renewal in embryonic stem cells JOURNAL Genes Dev 21 (20), 2545-2557 (2007) PUBMED 17938240 REFERENCE 3 (bases 1 to 1324) AUTHORS Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, DeCoste C, Schafer X, Lun Y and Lemischka IR. TITLE Dissecting self-renewal in stem cells with RNA interference JOURNAL Nature 442 (7102), 533-538 (2006) PUBMED 16767105 REFERENCE 4 (bases 1 to 1324) AUTHORS Narducci MG, Fiorenza MT, Kang SM, Bevilacqua A, Di Giacomo M, Remotti D, Picchio MC, Fidanza V, Cooper MD, Croce CM, Mangia F and Russo G. TITLE TCL1 participates in early embryonic development and...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 1032..1394 /gene="Ago4" /gene_synonym="Eif2c4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1188..1190,1233..1235,1275..1277,1287..1289, 1341..1343,1362..1364,1368..1370) /gene="Ago4" /gene_synonym="Eif2c4" /note="nucleic acid...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 933..1295 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1089..1091,1134..1136,1176..1178,1188..1190, 1242..1244,1263..1265,1269..1271) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-...
misc_feature 177..518 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(312..314,357..359,399..401,411..413,465..467, 486..488,492..494) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
misc_feature 174..515 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(309..311,354..356,396..398,408..410,462..464, 483..485,489..491) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
misc_feature 6283..6624 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(6418..6420,6463..6465,6505..6507,6517..6519, 6571..6573,6592..6594,6598..6600) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
misc_feature 6319..6660 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(6454..6456,6499..6501,6541..6543,6553..6555, 6607..6609,6628..6630,6634..6636) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
exon 315..617 /gene="Rpa3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 617) AUTHORS McJunkin,K., Mazurek,A., Premsrirut,P.K., Zuber,J., Dow,L.E., Simon,J., Stillman,B. and Lowe,S.W. TITLE Reversible suppression of an essential gene in adult mice using transgenic RNA interference JOURNAL Proc Natl Acad Sci U S A 108 (17), 7113-7118 (2011) PUBMED 21482754 REFERENCE 2 (bases 1 to 617) AUTHORS Sakaguchi,K., Ishibashi,T., Uchiyama,Y. and Iwabata,K. TITLE The multi-replication protein A (RPA) system--a new perspective JOURNAL FEBS J 276 (4), 943-963 (2009) PUBMED 19154342...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 374..736 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(530..532,575..577,617..619,629..631,683..685, 704..706,710..712) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 381..743 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(537..539,582..584,624..626,636..638,690..692, 711..713,717..719) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 666..1028 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(822..824,867..869,909..911,921..923,975..977, 996..998,1002..1004) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 886..1248 /gene="Ago4" /gene_synonym="Eif2c4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1042..1044,1087..1089,1129..1131,1141..1143, 1195..1197,1216..1218,1222..1224) /gene="Ago4" /gene_synonym="Eif2c4" /note="nucleic acid-...
PUBMED 21296577 REFERENCE 4 (bases 1 to 2860) AUTHORS Wang CH, Chan YM, Tang RH, Xiao B, Lu P, Keramaris-Vrantsis E, Zheng H, Qiao C, Jiang J, Li J, Ma HI, Lu Q and Xiao X. TITLE Post-Natal knockdown of fukutin-related protein expression in muscle by long-termRNA interference induces dystrophic pathology [corrected] JOURNAL Am J Pathol 178 (1), 261-272 (2011) PUBMED 21224063 REMARK Erratum:[Am J Pathol. 2011 Mar;178(3):1406] REFERENCE 5 (bases 1 to 2860) AUTHORS Chan YM, Keramaris-Vrantsis E, Lidov HG, Norton JH, Zinchenko N, Gruber HE, Thresher R, Blake DJ, Ashar J, Rosenfeld J and Lu QL....
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 785..1135 /gene="Ago4" /gene_synonym="Eif2c4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(941..943,986..988,1028..1030,1040..1042,1094..1096, 1115..1117,1121..1123) /gene="Ago4" /gene_synonym="Eif2c4" /note="nucleic acid-...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 871..1233 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1027..1029,1072..1074,1114..1116,1126..1128, 1180..1182,1201..1203,1207..1209) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-...
domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 684..1046 /gene="Ago2" /gene_synonym="eIF2C 2; Eif2c2" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(840..842,885..887,927..929,939..941,993..995, 1014..1016,1020..1022) /gene="Ago2" /gene_synonym="eIF2C 2; Eif2c2" /note="nucleic acid-...
PUBMED 16103226 REFERENCE 6 (bases 1 to 3326) AUTHORS Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E., Fan,J.B., Abraham,R.T. and Jiang,W. TITLE Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005) PUBMED 15843429 REFERENCE 7 (bases 1 to 3326) AUTHORS Tomas,A., Futter,C. and Moss,S.E. TITLE Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis JOURNAL J Cell Biol 165 (6), 813-822 (2004) PUBMED 15197175 REFERENCE...
REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 2949) AUTHORS Zhu C, Zhao J, Bibikova M, Leverson JD, Bossy-Wetzel E, Fan JB, Abraham RT and Jiang W. TITLE Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005) PUBMED 15843429 REFERENCE 4 (bases 1 to 2949) AUTHORS Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU and Barr FA. TITLE Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis JOURNAL...
RNA biology from an atlas of mammalian mRNA-binding proteins JOURNAL Cell 149 (6), 1393-1406 (2012) PUBMED 22658674 REFERENCE 6 (bases 1 to 2724) AUTHORS Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J. TITLE Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos JOURNAL Development 132 (11), 2599-2609 (2005) PUBMED 15857914...
JOURNAL Nucleic Acids Res 34 (1), 286-294 (2006) PUBMED 16407335 REMARK Publication Status: Online-Only REFERENCE 7 (bases 1 to 5279) AUTHORS Raineri,I., Wegmueller,D., Gross,B., Certa,U. and Moroni,C. TITLE Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference JOURNAL Nucleic Acids Res 32 (4), 1279-1288 (2004) PUBMED 14976220 REMARK Publication Status: Online-Only...
site" /db_xref="CDD:350189" misc_feature 2278..2544 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:460900" misc_feature 3046..3414 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
costimulator mRNAs and control follicular helper T cell differentiation JOURNAL Immunity 38 (4), 655-668 (2013) PUBMED 23583643 REFERENCE 5 (bases 1 to 2160) AUTHORS Xie,J., Wang,Y., Bao,J., Ma,Y., Zou,Z., Tang,Z., Dong,R. and Wen,H. TITLE Immune tolerance induced by RelB short-hairpin RNA interference dendritic cells in liver transplantation JOURNAL J Surg Res 180 (1), 169-175 (2013) PUBMED 23196258 REFERENCE 6 (bases 1 to 2160) AUTHORS Bieg,S., Simonson,W., Ellefsen,K. and Lernmark,A. TITLE Rel B is an early marker of autoimmune islet inflammation in the biobreeding (BB) rat JOURNAL Pancreas...
Publication Status: Online-Only REFERENCE 5 (bases 1 to 3006) AUTHORS Gruber,J.J., Zatechka,D.S., Sabin,L.R., Yong,J., Lum,J.J., Kong,M., Zong,W.X., Zhang,Z., Lau,C.K., Rawlings,J., Cherry,S., Ihle,J.N., Dreyfuss,G. and Thompson,C.B. TITLE Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation JOURNAL Cell 138 (2), 328-339 (2009) PUBMED 19632182...
site" /db_xref="CDD:350189" misc_feature 1954..2220 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:460900" misc_feature 2722..3090 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
site" /db_xref="CDD:350189" misc_feature 2116..2382 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:460900" misc_feature 2884..3252 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
site" /db_xref="CDD:350189" misc_feature 2202..2468 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:460900" misc_feature 2970..3338 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
site" /db_xref="CDD:350189" misc_feature 2246..2512 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:460900" misc_feature 3014..3382 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
E.Y., Liu,W., Kafri,T., van Praag,H. and Yan,Z. TITLE Regulation of AMPA receptor channels and synaptic plasticity by cofilin phosphatase Slingshot in cortical neurons JOURNAL J Physiol 588 (Pt 13), 2361-2371 (2010) PUBMED 20442266 REMARK GeneRIF: uppressing endogenous Slingshot with small RNA interference or function-blocking antibody led to a dramatic reduction of AMPA receptor-mediated excitatory postsynaptic currents REFERENCE 6 (bases 1 to 8551) AUTHORS Huang,T.Y., Minamide,L.S., Bamburg,J.R. and Bokoch,G.M. TITLE Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation...
site" /db_xref="CDD:350189" misc_feature 2121..2387 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:460900" misc_feature 2889..3257 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
site" /db_xref="CDD:350189" misc_feature 2434..2700 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:460900" misc_feature 3202..3570 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
REFERENCE 2 (bases 1 to 3806) AUTHORS Tsai,J.W., Lian,W.N., Kemal,S., Kriegstein,A.R. and Vallee,R.B. TITLE Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear migration in neural stem cells JOURNAL Nat Neurosci 13 (12), 1463-1471 (2010) PUBMED 21037580 REMARK GeneRIF: RNA interference screening of kinesin genes identifies Kif1a, a member of the kinesin-3 family, as the motor for basally directed nuclear movement in neural stem cells. REFERENCE 3 (bases 1 to 3806) AUTHORS Insinna,C., Humby,M., Sedmak,T., Wolfrum,U. and Besharse,J.C. TITLE Different roles for KIF17 and kinesin II in...
in ethidium bromide-induced demyelination in rats. REFERENCE 3 (bases 1 to 2510) AUTHORS Song XJ, Han W, He R, Li TY, Xie LL, Cheng L, Chen HS and Jiang L. TITLE Alterations of Hippocampal Myelin Sheath and Axon Sprouting by Status Convulsion and Regulating Lingo-1 Expression with RNA Interference in Immature and Adult Rats JOURNAL Neurochem Res 43 (3), 721-735 (2018) PUBMED 29383653 REMARK GeneRIF: in both immature and adult brains, Lingo-1 signaling plays important roles in seizure-induced damage to myelin sheaths and axon growth REFERENCE 4 (bases 1 to 2510) AUTHORS Shao Z, Lee X, Huang G,...
an early stage in ER-to-Golgi trafficking JOURNAL Mol Biol Cell 22 (12), 2083-2093 (2011) PUBMED 21525244 REFERENCE 3 (bases 1 to 4470) AUTHORS Wendler,F., Gillingham,A.K., Sinka,R., Rosa-Ferreira,C., Gordon,D.E., Franch-Marro,X., Peden,A.A., Vincent,J.P. and Munro,S. TITLE A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway JOURNAL EMBO J 29 (2), 304-314 (2010) PUBMED 19942856...
constituents to axons REFERENCE 4 (bases 1 to 4617) AUTHORS Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E., Fan,J.B., Abraham,R.T. and Jiang,W. TITLE Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005) PUBMED 15843429 REFERENCE 5 (bases 1 to 4617) AUTHORS Skop,A.R., Liu,H., Yates,J. 3rd, Meyer,B.J. and Heald,R. TITLE Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms JOURNAL Science 305 (5680), 61-66 (2004) PUBMED...
localization to the dendrites REFERENCE 7 (bases 1 to 4731) AUTHORS Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E., Fan,J.B., Abraham,R.T. and Jiang,W. TITLE Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005) PUBMED 15843429 REFERENCE 8 (bases 1 to 4731) AUTHORS Cassimeris,L. and Morabito,J. TITLE TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly JOURNAL Mol Biol Cell...
PUBMED 16431929 REFERENCE 10 (bases 1 to 7012) AUTHORS Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E., Fan,J.B., Abraham,R.T. and Jiang,W. TITLE Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005) PUBMED 15843429...
Tsukihara,T. TITLE A high-resolution structure of the pre-microRNA nuclear export machinery JOURNAL Science 326 (5957), 1275-1279 (2009) PUBMED 19965479 REFERENCE 7 (bases 1 to 4927) AUTHORS Yi,R., Doehle,B.P., Qin,Y., Macara,I.G. and Cullen,B.R. TITLE Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs JOURNAL RNA 11 (2), 220-226 (2005) PUBMED 15613540 REFERENCE 8 (bases 1 to 4927) AUTHORS Yi,R., Qin,Y., Macara,I.G. and Cullen,B.R. TITLE Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs JOURNAL Genes Dev...
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0.213 | 0.212 | count_done; http://172.18.8.71:7700/v1/refseq/query?q=((full_search:*:RNA+interference)%7C(nt:RNA+interference)%7C(aa:RNA+interference))?source=Rattus norvegicus (Norway rat)?to=0&format=json
0.326 | 0.113 | search_done; http://172.18.8.71:7700/v1/refseq/query?q=((full_search:*:RNA+interference)%7C(nt:RNA+interference)%7C(aa:RNA+interference))?source=Rattus norvegicus (Norway rat)?to=49?from=0?snippet=full_search?drilldown=source?get=accession,version,gi,length,symbol,synonym,geneid,division,source,definition&format=json
0.331 | 0.005 | cgi_end;
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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