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2024-04-20 20:34:56, GGRNA : RefSeq release 222 (Jan, 2024)
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Results:
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LOCUS XR_005506194 3900 bp RNA linear ROD 11-JUN-2023 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X2, misc_RNA. ACCESSION XR_005506194 VERSION XR_005506194.1 DBLINK BioProject: PRJNA677964 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational...
LOCUS XR_593163 3792 bp RNA linear ROD 11-JUN-2023 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X5, misc_RNA. ACCESSION XR_593163 VERSION XR_593163.3 DBLINK BioProject: PRJNA677964 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS XR_593161 3577 bp RNA linear ROD 11-JUN-2023 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X3, misc_RNA. ACCESSION XR_593161 VERSION XR_593161.3 DBLINK BioProject: PRJNA677964 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS XR_593162 3794 bp RNA linear ROD 11-JUN-2023 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X4, misc_RNA. ACCESSION XR_593162 VERSION XR_593162.3 DBLINK BioProject: PRJNA677964 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis....
LOCUS XM_234465 5878 bp mRNA linear ROD 11-JUN-2023 DEFINITION PREDICTED: Rattus norvegicus NRDE-2, necessary for RNA interference, domain containing (Nrde2), transcript variant X1, mRNA. ACCESSION XM_234465 VERSION XM_234465.10 DBLINK BioProject: PRJNA677964 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This...
inference="alignment:Splign:2.1.0" exon 662..954 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 954) AUTHORS Zhao Y, Goto M, Vaziri ND, Khazaeli M, Liu H, Farahanchi N, Khanifar E, Farzaneh T, Haslett PA, Moradi H and Soundarapandian MM. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects...
REFERENCE 2 (bases 1 to 2335) AUTHORS Tsujimoto R, Yurube T, Takeoka Y, Kanda Y, Miyazaki K, Ohnishi H, Kakiuchi Y, Miyazaki S, Zhang Z, Takada T, Kuroda R and Kakutani K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2335) AUTHORS Cheng H, Xu B,...
inference="alignment:Splign:2.1.0" exon 891..1779 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 1779) AUTHORS Zhao Y, Goto M, Vaziri ND, Khazaeli M, Liu H, Farahanchi N, Khanifar E, Farzaneh T, Haslett PA, Moradi H and Soundarapandian MM. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects...
inference="alignment:Splign:2.1.0" exon 206..3756 /gene="Tmem167a" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 3756) AUTHORS Wendler F, Gillingham AK, Sinka R, Rosa-Ferreira C, Gordon DE, Franch-Marro X, Peden AA, Vincent JP and Munro S. TITLE A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway JOURNAL EMBO J 29 (2), 304-314 (2010) PUBMED 19942856...
Liu X and Suo X. TITLE Molecular cloning and protein characterization of swine 4-1BB JOURNAL Vet Immunol Immunopathol 153 (1-2), 35-44 (2013) PUBMED 23453329 REFERENCE 2 (bases 1 to 1410) AUTHORS Shi Y, Hu S, Song Q, Yu S, Zhou X, Yin J, Qin L and Qian H. TITLE Gene silencing of 4-1BB by RNA interference inhibits acute rejection in rats with liver transplantation JOURNAL Biomed Res Int 2013, 192738 (2013) PUBMED 23484089 REMARK GeneRIF: gene silencing of 4-1BB by RNA interference inhibits the acute rejection in rats with liver transplantation. REFERENCE 3 (bases 1 to 1410) AUTHORS Zhang J,...
REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JACYVU010000162.1 and FM038730.1. Summary: This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene...
Splign:2.1.0" exon 329..644 /gene="Tmem167b" /gene_synonym="RGD1564454" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 644) AUTHORS Wendler F, Gillingham AK, Sinka R, Rosa-Ferreira C, Gordon DE, Franch-Marro X, Peden AA, Vincent JP and Munro S. TITLE A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway JOURNAL EMBO J 29 (2), 304-314 (2010) PUBMED 19942856...
REFERENCE 2 (bases 1 to 2256) AUTHORS Tsujimoto R, Yurube T, Takeoka Y, Kanda Y, Miyazaki K, Ohnishi H, Kakiuchi Y, Miyazaki S, Zhang Z, Takada T, Kuroda R and Kakutani K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2256) AUTHORS Cheng H, Xu B,...
REFERENCE 2 (bases 1 to 2331) AUTHORS Tsujimoto R, Yurube T, Takeoka Y, Kanda Y, Miyazaki K, Ohnishi H, Kakiuchi Y, Miyazaki S, Zhang Z, Takada T, Kuroda R and Kakutani K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2331) AUTHORS Cheng H, Xu B,...
REFERENCE 2 (bases 1 to 2425) AUTHORS Tsujimoto R, Yurube T, Takeoka Y, Kanda Y, Miyazaki K, Ohnishi H, Kakiuchi Y, Miyazaki S, Zhang Z, Takada T, Kuroda R and Kakutani K. TITLE Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5 JOURNAL Osteoarthritis Cartilage 30 (3), 481-493 (2022) PUBMED 34958937 REMARK GeneRIF: Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5. REFERENCE 3 (bases 1 to 2425) AUTHORS Cheng H, Xu B,...
by NCBI staff. The reference sequence was derived from JACYVU010000162.1 and FM038730.1. On Sep 18, 2014 this sequence version replaced NM_001191765.1. Summary: This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene...
misc_feature <1509..1727 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1521..1523,1566..1568,1608..1610,1620..1622, 1674..1676,1695..1697,1701..1703) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="...
misc_feature 177..518 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(312..314,357..359,399..401,411..413,465..467, 486..488,492..494) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
misc_feature 184..525 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(319..321,364..366,406..408,418..420,472..474, 493..495,499..501) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_...
a druggable target in hypertension induced by chronic intermittent hypoxia JOURNAL Pharmacol Res 159, 104869 (2020) PUBMED 32416216 REFERENCE 4 (bases 1 to 2107) AUTHORS Drevytska T, Gonchar E, Okhai I, Lynnyk O, Mankovska I, Klionsky D and Dosenko V. TITLE The protective effect of Hif3a RNA interference and HIF-prolyl hydroxylase inhibition on cardiomyocytes under anoxia-reoxygenation JOURNAL Life Sci 202, 131-139 (2018) PUBMED 29660430 REMARK GeneRIF: Hif3a RNA interference and HIF-prolyl hydroxylase inhibition protect cardiomyocytes against anoxia-reoxygenation injury via the HIF signaling...
misc_feature 2881..3222 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(3016..3018,3061..3063,3103..3105,3115..3117, 3169..3171,3190..3192,3196..3198) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
misc_feature 2917..3258 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(3052..3054,3097..3099,3139..3141,3151..3153, 3205..3207,3226..3228,3232..3234) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD...
Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4366) AUTHORS Vidal RL, Fuentes P, Valenzuela JI, Alvarado-Diaz CP, Ramirez OA, Kukuljan M and Couve A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:430160" misc_feature 385..747 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(541..543,586..588,628..630,640..642,694..696, 715..717,721..723) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:430160" misc_feature 385..747 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(541..543,586..588,628..630,640..642,694..696, 715..717,721..723) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-binding...
inference="alignment:Splign:2.1.0" exon 1254..1620 /gene="Angptl3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 1620) AUTHORS Zhao Y, Goto M, Vaziri ND, Khazaeli M, Liu H, Farahanchi N, Khanifar E, Farzaneh T, Haslett PA, Moradi H and Soundarapandian MM. TITLE RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia JOURNAL J Pharmacol Exp Ther 376 (3), 428-435 (2021) PUBMED 33443084 REMARK GeneRIF: RNA Interference Targeting Liver Angiopoietin-Like Protein 3...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:430160" misc_feature 1023..1373 /gene="Ago4" /gene_synonym="Eif2c4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1179..1181,1224..1226,1266..1268,1278..1280, 1332..1334,1353..1355,1359..1361) /gene="Ago4" /gene_synonym="Eif2c4" /note="nucleic acid...
domain; Region: ArgoL1; pfam08699" /db_xref="CDD:430160" misc_feature 711..1073 /gene="Ago2" /gene_synonym="eIF2C 2; Eif2c2" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(867..869,912..914,954..956,966..968,1020..1022, 1041..1043,1047..1049) /gene="Ago2" /gene_synonym="eIF2C 2; Eif2c2" /note="nucleic acid...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:430160" misc_feature 871..1233 /gene="Ago1" /gene_synonym="Eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1027..1029,1072..1074,1114..1116,1126..1128, 1180..1182,1201..1203,1207..1209) /gene="Ago1" /gene_synonym="Eif2c1" /note="nucleic acid-...
Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 2410) AUTHORS Vidal RL, Fuentes P, Valenzuela JI, Alvarado-Diaz CP, Ramirez OA, Kukuljan M and Couve A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
a druggable target in hypertension induced by chronic intermittent hypoxia JOURNAL Pharmacol Res 159, 104869 (2020) PUBMED 32416216 REFERENCE 4 (bases 1 to 2065) AUTHORS Drevytska T, Gonchar E, Okhai I, Lynnyk O, Mankovska I, Klionsky D and Dosenko V. TITLE The protective effect of Hif3a RNA interference and HIF-prolyl hydroxylase inhibition on cardiomyocytes under anoxia-reoxygenation JOURNAL Life Sci 202, 131-139 (2018) PUBMED 29660430 REMARK GeneRIF: Hif3a RNA interference and HIF-prolyl hydroxylase inhibition protect cardiomyocytes against anoxia-reoxygenation injury via the HIF signaling...
regulate self-renewal in embryonic stem cells JOURNAL Genes Dev 21 (20), 2545-2557 (2007) PUBMED 17938240 REFERENCE 3 (bases 1 to 1324) AUTHORS Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, DeCoste C, Schafer X, Lun Y and Lemischka IR. TITLE Dissecting self-renewal in stem cells with RNA interference JOURNAL Nature 442 (7102), 533-538 (2006) PUBMED 16767105 REFERENCE 4 (bases 1 to 1324) AUTHORS Narducci MG, Fiorenza MT, Kang SM, Bevilacqua A, Di Giacomo M, Remotti D, Picchio MC, Fidanza V, Cooper MD, Croce CM, Mangia F and Russo G. TITLE TCL1 participates in early embryonic development and...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:430160" misc_feature 1032..1394 /gene="Ago4" /gene_synonym="Eif2c4" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1188..1190,1233..1235,1275..1277,1287..1289, 1341..1343,1362..1364,1368..1370) /gene="Ago4" /gene_synonym="Eif2c4" /note="nucleic acid...
Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 2498) AUTHORS Vidal RL, Fuentes P, Valenzuela JI, Alvarado-Diaz CP, Ramirez OA, Kukuljan M and Couve A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:430160" misc_feature 933..1295 /gene="Ago3" /gene_synonym="Eif2c3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1089..1091,1134..1136,1176..1178,1188..1190, 1242..1244,1263..1265,1269..1271) /gene="Ago3" /gene_synonym="Eif2c3" /note="nucleic acid-...
PUBMED 21296577 REFERENCE 4 (bases 1 to 2860) AUTHORS Wang CH, Chan YM, Tang RH, Xiao B, Lu P, Keramaris-Vrantsis E, Zheng H, Qiao C, Jiang J, Li J, Ma HI, Lu Q and Xiao X. TITLE Post-Natal knockdown of fukutin-related protein expression in muscle by long-termRNA interference induces dystrophic pathology [corrected] JOURNAL Am J Pathol 178 (1), 261-272 (2011) PUBMED 21224063 REMARK Erratum:[Am J Pathol. 2011 Mar;178(3):1406] REFERENCE 5 (bases 1 to 2860) AUTHORS Chan YM, Keramaris-Vrantsis E, Lidov HG, Norton JH, Zinchenko N, Gruber HE, Thresher R, Blake DJ, Ashar J, Rosenfeld J and Lu QL....
RNA biology from an atlas of mammalian mRNA-binding proteins JOURNAL Cell 149 (6), 1393-1406 (2012) PUBMED 22658674 REFERENCE 6 (bases 1 to 2724) AUTHORS Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J. TITLE Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos JOURNAL Development 132 (11), 2599-2609 (2005) PUBMED 15857914...
REFERENCE 1 (bases 1 to 2099) AUTHORS Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA. TITLE Defining the membrane proteome of NK cells JOURNAL J Mass Spectrom 45 (1), 1-25 (2010) PUBMED 19946888 REFERENCE 2 (bases 1 to 2099) AUTHORS Suga K, Hattori H, Saito A and Akagawa K. TITLE RNA interference-mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles JOURNAL FEBS Lett 579 (20), 4226-4234 (2005) PUBMED 16081076 REFERENCE 3 (bases 1 to 2099) AUTHORS Peng J, Huang CH, Short MK and Jubinsky PT. TITLE Magmas gene structure and evolution...
Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4397) AUTHORS Vidal RL, Fuentes P, Valenzuela JI, Alvarado-Diaz CP, Ramirez OA, Kukuljan M and Couve A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4409) AUTHORS Vidal RL, Fuentes P, Valenzuela JI, Alvarado-Diaz CP, Ramirez OA, Kukuljan M and Couve A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse JOURNAL Neuron 88 (6), 1173-1191 (2015) PUBMED 26627310 REFERENCE 2 (bases 1 to 4378) AUTHORS Vidal RL, Fuentes P, Valenzuela JI, Alvarado-Diaz CP, Ramirez OA, Kukuljan M and Couve A. TITLE RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons JOURNAL Mol Cell Neurosci 51 (1-2), 1-11 (2012) PUBMED 22828129 REMARK GeneRIF: RNA interference of Marlin-1 in vivo results in abnormal migration and abnormal morphology of newborn pyramidal...
to influenza A H1N1 virus, West Nile virus, and dengue virus JOURNAL Cell 139 (7), 1243-1254 (2009) PUBMED 20064371 REFERENCE 8 (bases 1 to 672) AUTHORS Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J. TITLE Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos JOURNAL Development 132 (11), 2599-2609 (2005) PUBMED 15857914...
site" /db_xref="CDD:350189" misc_feature 2364..2630 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:427264" misc_feature 3132..3500 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1 JOURNAL Development 139 (7), 1276-1284 (2012) PUBMED 22357932 REFERENCE 2 (bases 1 to 738) AUTHORS Vidigal JA, Morkel M, Wittler L, Brouwer-Lehmitz A, Grote P, Macura K and Herrmann BG. TITLE An inducible RNA interference system for the functional dissection of mouse embryogenesis JOURNAL Nucleic Acids Res 38 (11), e122 (2010) PUBMED 20350929 REFERENCE 3 (bases 1 to 738) AUTHORS Zizic Mitrecic M, Mitrecic D, Pochet R, Kostovic-Knezevic L and Gajovic S. TITLE The mouse gene Noto is expressed in the tail bud and...
exon 315..617 /gene="Rpa3" /inference="alignment:Splign:2.1.0" ORIGIN // REFERENCE 1 (bases 1 to 617) AUTHORS McJunkin K, Mazurek A, Premsrirut PK, Zuber J, Dow LE, Simon J, Stillman B and Lowe SW. TITLE Reversible suppression of an essential gene in adult mice using transgenic RNA interference JOURNAL Proc Natl Acad Sci U S A 108 (17), 7113-7118 (2011) PUBMED 21482754 REFERENCE 2 (bases 1 to 617) AUTHORS Sakaguchi K, Ishibashi T, Uchiyama Y and Iwabata K. TITLE The multi-replication protein A (RPA) system--a new perspective JOURNAL FEBS J 276 (4), 943-963 (2009) PUBMED 19154342 REMARK Review...
site" /db_xref="CDD:350189" misc_feature 2043..2309 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:427264" misc_feature 2811..3179 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
site" /db_xref="CDD:350189" misc_feature 2129..2395 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:427264" misc_feature 2897..3265 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
site" /db_xref="CDD:350189" misc_feature 2176..2442 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:427264" misc_feature 2944..3312 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
site" /db_xref="CDD:350189" misc_feature 2231..2497 /gene="Dicer1" /note="Dicer dimerization domain; Region: Dicer_dimer; pfam03368" /db_xref="CDD:427264" misc_feature 2999..3367 /gene="Dicer1" /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse involved in cleaving dsRNA in the RNA interference pathway. It generates dsRNAs which are approximately 20 bp long (siRNAs), which in turn target hydrolysis of homologous RNAs. PAZ domains are named...; Region: PAZ_dicer_like; cd02843" /db_xref="CDD:239209" misc_feature order...
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query_string : "RNA interference" |
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0.000 | 0.000 | search_start;
0.219 | 0.219 | count_done; http://172.18.8.71:7700/v1/refsub/query?q=((full_search:*:RNA+interference)%7C(nt:RNA+interference)%7C(aa:RNA+interference))?source=Rattus norvegicus (Norway rat)?to=0&format=json
0.294 | 0.075 | search_done; http://172.18.8.71:7700/v1/refsub/query?q=((full_search:*:RNA+interference)%7C(nt:RNA+interference)%7C(aa:RNA+interference))?source=Rattus norvegicus (Norway rat)?to=49?from=0?snippet=full_search?drilldown=source?get=accession,version,gi,length,symbol,synonym,geneid,division,source,definition&format=json
0.300 | 0.005 | cgi_end;
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GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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