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2020-10-30 19:52:07, GGRNA : RefSeq release 201 (Jul, 2020)

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Results:

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Homo sapiens Nanog homeobox retrogene P8 (NANOGP8), mRNA. (1886 bp)
LOCUS NM_001355281 1886 bp mRNA linear PRI 13-MAY-2020 DEFINITION Homo sapiens Nanog homeobox retrogene P8 (NANOGP8), mRNA. ACCESSION NM_001355281 VERSION NM_001355281.2 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021231.8. On Dec 2, 2019 this sequence version replaced...
Synonym: NANOGP1; PN8
NM_001355281.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens Nanog homeobox (NANOG), transcript variant 1, mRNA. (5182 bp)
LOCUS NM_024865 5182 bp mRNA linear PRI 04-JUL-2020 DEFINITION Homo sapiens Nanog homeobox (NANOG), transcript variant 1, mRNA. ACCESSION NM_024865 VERSION NM_024865.4 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC425336.1, AK290896.1, AC006517.46 and AI656990.1. On Nov 22, 2018 this...
NM_024865.4 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens NANOG neighbor homeobox (NANOGNB), mRNA. (907 bp)
LOCUS NM_001145465 907 bp mRNA linear PRI 01-JUL-2020 DEFINITION Homo sapiens NANOG neighbor homeobox (NANOGNB), mRNA. ACCESSION NM_001145465 XR_040558 XR_040559 XR_040560 VERSION NM_001145465.1 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY151139.1. On or before Mar...
NM_001145465.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens Nanog homeobox (NANOG), transcript variant 2, mRNA. (2049 bp)
LOCUS NM_001297698 2049 bp mRNA linear PRI 14-JUN-2020 DEFINITION Homo sapiens Nanog homeobox (NANOG), transcript variant 2, mRNA. ACCESSION NM_001297698 XM_005253484 VERSION NM_001297698.2 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC425336.1, AY578089.1, AC006517.46 and AI656990.1. On May 31, 2019...
NM_001297698.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens estrogen related receptor beta (ESRRB), transcript variant 1, mRNA. (3090 bp)
synonym="DFNB35; ERR beta-2; ERR2; ERRb; ERRbeta2; ESRL2; NR3B2" /note="propagated from UniProtKB/Swiss-Prot (O95718.3); Region: Interaction with NANOG. /evidence=ECO:0000250|UniProtKB:Q61539" misc_feature 739..1026 /gene="ESRRB" /gene_synonym="DFNB35; ERR beta-2; ERR2; ERRb; ERRbeta2; ESRL2;...REMARK GeneRIF: The orphan nuclear receptor Esrrb plays a pioneering role in recruiting the core pluripotency factors Oct4, Sox2, and Nanog to inactive enhancers in closed chromatin during the reprogramming of epiblast stem cells. Erratum:[Cell Stem Cell. 2018 Dec 6;23(6):900-904. PMID: 30526884]...
Synonym: DFNB35; ERR beta-2; ERR2; ERRb; ERRbeta2; ESRL2; NR3B2
NM_004452.4 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens estrogen related receptor beta (ESRRB), transcript variant 2, mRNA. (5009 bp)
M and Scholer HR. TITLE Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency JOURNAL Cell Stem Cell 23 (2), 266-275 (2018) PUBMED 29910149 REMARK GeneRIF: The orphan nuclear receptor Esrrb plays a pioneering role in recruiting the core pluripotency factors Oct4, Sox2, and Nanog to inactive enhancers in closed chromatin during the reprogramming of epiblast stem cells. Erratum:[Cell Stem Cell. 2018 Dec 6;23(6):900-904. PMID: 30526884] REFERENCE 3 (bases 1 to 5009) AUTHORS Kumari K, Adhya AK, Rath AK, Reddy PB and Mishra SK. TITLE Estrogen-related receptors alpha, beta and...
Synonym: DFNB35; ERR beta-2; ERR2; ERRb; ERRbeta2; ESRL2; NR3B2
NM_001379180.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens developmental pluripotency associated 5 (DPPA5), mRNA. (659 bp)
db_xref="dbSNP:76770796" variation 659 /gene="DPPA5" /gene_synonym="ESG1" /replace="a" /replace="g" /db_xref="dbSNP:1472870653" ORIGIN // REFERENCE 1 (bases 1 to 659) AUTHORS Qian X, Kim JK, Tong W, Villa-Diaz LG and Krebsbach PH. TITLE DPPA5 Supports Pluripotency and Reprogramming by Regulating NANOG Turnover JOURNAL Stem Cells 34 (3), 588-600 (2016) PUBMED 26661329 REMARK GeneRIF: Our study provides new insight into the function of DPPA5 and NANOG regulation in human pluripotent stem cell . REFERENCE 2 (bases 1 to 659) AUTHORS Aoki T, Ohnishi H, Oda Y, Tadokoro M, Sasao M, Kato H, Hattori K...
Synonym: ESG1
NM_001025290.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens developmental pluripotency associated 3 (DPPA3), mRNA. (1100 bp)
growth in serum depleted media. REFERENCE 3 (bases 1 to 1100) AUTHORS Blinka S, Reimer MH Jr, Pulakanti K and Rao S. TITLE Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes JOURNAL Cell Rep 17 (1), 19-28 (2016) PUBMED 27681417 REMARK GeneRIF: Super-...AUTHORS Clark AT, Rodriguez RT, Bodnar MS, Abeyta MJ, Cedars MI, Turek PJ, Firpo MT and Reijo Pera RA. TITLE Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma JOURNAL Stem Cells 22 (2), 169-179 (2004)...
Synonym: Pgc7; STELLA
NM_199286.4 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 4, mRNA. (3442 bp)
gene="FLI1" /gene_synonym="BDPLT21; EWSR2; SIC-1" ORIGIN // REFERENCE 1 (bases 1 to 3442) AUTHORS Park SW, Do HJ, Choi W and Kim JH. TITLE Fli-1 promotes proliferation and upregulates NANOGP8 expression in T-lymphocyte leukemia cells JOURNAL Biochimie 168, 1-9 (2020) PUBMED 31626853 REMARK GeneRIF: The authors demonstrate that Fli-1 is a novel upstream transcriptional activator of NANOGP8 (Nanog homeobox retrogene P8) and provide the molecular details of Fli-1-mediated NANOGP8 gene expression. REFERENCE 2 (bases 1 to 3442) AUTHORS Romswinkel A, Infanger M, Dietz C, Strube F and Kraus A. TITLE...
Synonym: BDPLT21; EWSR2; SIC-1
NM_001271012.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens growth differentiation factor 3 (GDF3), mRNA. (1236 bp)
African Americans JOURNAL Pharmacogenomics J. 14 (1), 35-40 (2014) PUBMED 23400010 REFERENCE 5 (bases 1 to 1236) AUTHORS Park SW, Lim HY, Do HJ, Sung B, Huh SH, Uhm SJ, Song H, Chung HJ, Kim JH, Kim NH and Kim JH. TITLE Regulation of human growth and differentiation factor 3 gene expression by NANOG in human embryonic carcinoma NCCIT cells JOURNAL FEBS Lett. 586 (19), 3529-3535 (2012) PUBMED 22963770 REMARK GeneRIF: first evidence that NANOG is a transcriptional activator of the expression of the oncogenic growth factor GDF3 in embryonic carcinoma cells REFERENCE 6 (bases 1 to 1236) AUTHORS...
Synonym: KFS3; MCOP7; MCOPCB6
NM_020634.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens TARBP2 subunit of RISC loading complex (TARBP2), transcript variant 3, mRNA. (1448 bp)
REMARK GeneRIF: TARBP2 participates in the interaction between IRF7 and TRAF6, thereby suppressing TRAF6-mediated K63-linked ubiquitination of IRF7. REFERENCE 4 (bases 1 to 1448) AUTHORS Lai HH, Li CW, Hong CC, Sun HY, Chiu CF, Ou DL and Chen PS. TITLE TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma JOURNAL Mol Oncol 13 (4), 928-945 (2019) PUBMED 30657254 REMARK GeneRIF: The TARBP2 protein was destabilized through autophagic-lysosomal proteolysis, thereby stabilizing the expression of the cancer stem cell marker protein Nanog, which...
Synonym: LOQS; TRBP; TRBP1; TRBP2
NM_004178.4 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 1, mRNA. (3825 bp)
replace="a" /replace="g" /db_xref="dbSNP:1329078026" ORIGIN // REFERENCE 1 (bases 1 to 3825) AUTHORS Park SW, Do HJ, Choi W and Kim JH. TITLE Fli-1 promotes proliferation and upregulates NANOGP8 expression in T-lymphocyte leukemia cells JOURNAL Biochimie 168, 1-9 (2020) PUBMED 31626853 REMARK GeneRIF: The authors demonstrate that Fli-1 is a novel upstream transcriptional activator of NANOGP8 (Nanog homeobox retrogene P8) and provide the molecular details of Fli-1-mediated NANOGP8 gene expression. REFERENCE 2 (bases 1 to 3825) AUTHORS Romswinkel A, Infanger M, Dietz C, Strube F and Kraus A....
Synonym: BDPLT21; EWSR2; SIC-1
NM_002017.5 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens TARBP2 subunit of RISC loading complex (TARBP2), transcript variant 1, mRNA. (1510 bp)
REMARK GeneRIF: TARBP2 participates in the interaction between IRF7 and TRAF6, thereby suppressing TRAF6-mediated K63-linked ubiquitination of IRF7. REFERENCE 4 (bases 1 to 1510) AUTHORS Lai HH, Li CW, Hong CC, Sun HY, Chiu CF, Ou DL and Chen PS. TITLE TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma JOURNAL Mol Oncol 13 (4), 928-945 (2019) PUBMED 30657254 REMARK GeneRIF: The TARBP2 protein was destabilized through autophagic-lysosomal proteolysis, thereby stabilizing the expression of the cancer stem cell marker protein Nanog, which...
Synonym: LOQS; TRBP; TRBP1; TRBP2
NM_134323.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 2, mRNA. (4049 bp)
gene="FLI1" /gene_synonym="BDPLT21; EWSR2; SIC-1" ORIGIN // REFERENCE 1 (bases 1 to 4049) AUTHORS Park SW, Do HJ, Choi W and Kim JH. TITLE Fli-1 promotes proliferation and upregulates NANOGP8 expression in T-lymphocyte leukemia cells JOURNAL Biochimie 168, 1-9 (2020) PUBMED 31626853 REMARK GeneRIF: The authors demonstrate that Fli-1 is a novel upstream transcriptional activator of NANOGP8 (Nanog homeobox retrogene P8) and provide the molecular details of Fli-1-mediated NANOGP8 gene expression. REFERENCE 2 (bases 1 to 4049) AUTHORS Romswinkel A, Infanger M, Dietz C, Strube F and Kraus A. TITLE...
Synonym: BDPLT21; EWSR2; SIC-1
NM_001167681.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens frizzled class receptor 9 (FZD9), mRNA. (2343 bp)
corresponded to that of a candidate tumorsuppressor gene in acute myeloid leukemia. REFERENCE 4 (bases 1 to 2343) AUTHORS Trubiani O, Zalzal SF, Paganelli R, Marchisio M, Giancola R, Pizzicannella J, Buhring HJ, Piattelli M, Caputi S and Nanci A. TITLE Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells JOURNAL J. Cell. Physiol. 225 (1), 123-131 (2010) PUBMED 20458727 REMARK GeneRIF: The presence of nanog, Oct-4, SSEA-1, and SSEA-4 suggests that periodontal ligament mesenchymal stem cells are...
Synonym: CD349; FZD3
NM_003508.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens FEZF1 antisense RNA 1 (FEZF1-AS1), long non-coding RNA. (2653 bp)
results highlight the importance of the FEZF1-AS1/miR-4443 axis during HCC development and progression. REFERENCE 5 (bases 1 to 2653) AUTHORS Zhang Z, Sun L, Zhang Y, Lu G, Li Y and Wei Z. TITLE Long non-coding RNA FEZF1-AS1 promotes breast cancer stemness and tumorigenesis via targeting miR-30a/Nanog axis JOURNAL J. Cell. Physiol. 233 (11), 8630-8638 (2018) PUBMED 29797562 REMARK GeneRIF: our study validate the important role of FEZF1-AS1/miR-30a/Nanog in breast cancer stemness and tumorigenesis, providing a novel insight and treatment strategy for breast cancer. REFERENCE 6...
NR_036484.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 3, mRNA. (4166 bp)
gene="FLI1" /gene_synonym="BDPLT21; EWSR2; SIC-1" ORIGIN // REFERENCE 1 (bases 1 to 4166) AUTHORS Park SW, Do HJ, Choi W and Kim JH. TITLE Fli-1 promotes proliferation and upregulates NANOGP8 expression in T-lymphocyte leukemia cells JOURNAL Biochimie 168, 1-9 (2020) PUBMED 31626853 REMARK GeneRIF: The authors demonstrate that Fli-1 is a novel upstream transcriptional activator of NANOGP8 (Nanog homeobox retrogene P8) and provide the molecular details of Fli-1-mediated NANOGP8 gene expression. REFERENCE 2 (bases 1 to 4166) AUTHORS Romswinkel A, Infanger M, Dietz C, Strube F and Kraus A. TITLE...
Synonym: BDPLT21; EWSR2; SIC-1
NM_001271010.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens checkpoint with forkhead and ring finger domains (CHFR), transcript variant 5, mRNA. (3015 bp)
with favorable treatment outcomes of irinotecan-based chemotherapy in patients with metastatic colorectal cancer. REFERENCE 2 (bases 1 to 3015) AUTHORS Woo SR, Lee HJ, Oh SJ, Kim S, Park SH, Lee J, Song KH and Kim TW. TITLE Stabilization of HDAC1 via TCL1-pAKT-CHFR axis is a key element for NANOG-mediated multi-resistance and stem-like phenotype in immune-edited tumor cells JOURNAL Biochem. Biophys. Res. Commun. 503 (3), 1812-1818 (2018) PUBMED 30060952 REMARK GeneRIF: The results establish a firm molecular link in immune-edited tumor cells among NANOG, AKT, CHFR, and HDAC1, identifying HDAC1...
Synonym: RNF116; RNF196
NM_001161347.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens PBX homeobox 1 (PBX1), transcript variant 5, mRNA. (3056 bp)
REMARK GeneRIF: HNRPDL transforms hematopoietic cells and a novel HNRPDL/PBX1 axis plays an important role in human CML CD34(+) cells REFERENCE 2 (bases 1 to 3056) AUTHORS Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, Liu M, Zheng T, Zou F, Liu X, Jin M, Mu Y, Li G, Su G and Liu J. TITLE NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling JOURNAL Oxid Med Cell Longev 2019, 4286213 (2019) PUBMED 31885790 REMARK GeneRIF: Findings show that NANOG delays HF-MSC senescence by upregulating PBX1 and activating AKT signaling and that...
Synonym: CAKUHED
NM_001353131.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens checkpoint with forkhead and ring finger domains (CHFR), transcript variant 4, mRNA. (3168 bp)
with favorable treatment outcomes of irinotecan-based chemotherapy in patients with metastatic colorectal cancer. REFERENCE 2 (bases 1 to 3168) AUTHORS Woo SR, Lee HJ, Oh SJ, Kim S, Park SH, Lee J, Song KH and Kim TW. TITLE Stabilization of HDAC1 via TCL1-pAKT-CHFR axis is a key element for NANOG-mediated multi-resistance and stem-like phenotype in immune-edited tumor cells JOURNAL Biochem. Biophys. Res. Commun. 503 (3), 1812-1818 (2018) PUBMED 30060952 REMARK GeneRIF: The results establish a firm molecular link in immune-edited tumor cells among NANOG, AKT, CHFR, and HDAC1, identifying HDAC1...
Synonym: RNF116; RNF196
NM_018223.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens acrosin binding protein (ACRBP), mRNA. (1905 bp)
of cell cycle-regulated protein cyclin E, migration/invasion-regulated proteins MMP2 and MMP9. Publication Status: Online-Only REFERENCE 2 (bases 1 to 1905) AUTHORS Hu Q, Fu J, Luo B, Huang M, Guo W, Lin Y, Xie X and Xiao S. TITLE OY-TES-1 may regulate the malignant behavior of liver cancer via NANOG, CD9, CCND2 and CDCA3: a bioinformatic analysis combine with RNAi and oligonucleotide microarray JOURNAL Oncol. Rep. 33 (4), 1965-1975 (2015) PUBMED 25673160 REMARK GeneRIF: OY-TES-1 downregulation in liver cancer cells caused 2 opposite effects on cell proliferation: promotion by upregulating...
Synonym: CT23; OY-TES-1; SP32
NM_032489.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens checkpoint with forkhead and ring finger domains (CHFR), transcript variant 3, mRNA. (11228 bp)
with favorable treatment outcomes of irinotecan-based chemotherapy in patients with metastatic colorectal cancer. REFERENCE 2 (bases 1 to 11228) AUTHORS Woo SR, Lee HJ, Oh SJ, Kim S, Park SH, Lee J, Song KH and Kim TW. TITLE Stabilization of HDAC1 via TCL1-pAKT-CHFR axis is a key element for NANOG-mediated multi-resistance and stem-like phenotype in immune-edited tumor cells JOURNAL Biochem. Biophys. Res. Commun. 503 (3), 1812-1818 (2018) PUBMED 30060952 REMARK GeneRIF: The results establish a firm molecular link in immune-edited tumor cells among NANOG, AKT, CHFR, and HDAC1, identifying...
Synonym: RNF116; RNF196
NM_001161346.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens checkpoint with forkhead and ring finger domains (CHFR), transcript variant 2, mRNA. (3288 bp)
with favorable treatment outcomes of irinotecan-based chemotherapy in patients with metastatic colorectal cancer. REFERENCE 2 (bases 1 to 3288) AUTHORS Woo SR, Lee HJ, Oh SJ, Kim S, Park SH, Lee J, Song KH and Kim TW. TITLE Stabilization of HDAC1 via TCL1-pAKT-CHFR axis is a key element for NANOG-mediated multi-resistance and stem-like phenotype in immune-edited tumor cells JOURNAL Biochem. Biophys. Res. Commun. 503 (3), 1812-1818 (2018) PUBMED 30060952 REMARK GeneRIF: The results establish a firm molecular link in immune-edited tumor cells among NANOG, AKT, CHFR, and HDAC1, identifying HDAC1...
Synonym: RNF116; RNF196
NM_001161345.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens checkpoint with forkhead and ring finger domains (CHFR), transcript variant 1, mRNA. (3291 bp)
with favorable treatment outcomes of irinotecan-based chemotherapy in patients with metastatic colorectal cancer. REFERENCE 2 (bases 1 to 3291) AUTHORS Woo SR, Lee HJ, Oh SJ, Kim S, Park SH, Lee J, Song KH and Kim TW. TITLE Stabilization of HDAC1 via TCL1-pAKT-CHFR axis is a key element for NANOG-mediated multi-resistance and stem-like phenotype in immune-edited tumor cells JOURNAL Biochem. Biophys. Res. Commun. 503 (3), 1812-1818 (2018) PUBMED 30060952 REMARK GeneRIF: The results establish a firm molecular link in immune-edited tumor cells among NANOG, AKT, CHFR, and HDAC1, identifying HDAC1...
Synonym: RNF116; RNF196
NM_001161344.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens PBX homeobox 1 (PBX1), transcript variant 3, mRNA. (4162 bp)
REMARK GeneRIF: HNRPDL transforms hematopoietic cells and a novel HNRPDL/PBX1 axis plays an important role in human CML CD34(+) cells REFERENCE 2 (bases 1 to 4162) AUTHORS Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, Liu M, Zheng T, Zou F, Liu X, Jin M, Mu Y, Li G, Su G and Liu J. TITLE NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling JOURNAL Oxid Med Cell Longev 2019, 4286213 (2019) PUBMED 31885790 REMARK GeneRIF: Findings show that NANOG delays HF-MSC senescence by upregulating PBX1 and activating AKT signaling and that...
Synonym: CAKUHED
NM_001204963.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens KH domain containing 3 like, subcortical maternal complex member (KHDC3L), mRNA. (1037 bp)
family JOURNAL Genomics 90 (5), 583-594 (2007) PUBMED 17913455 REMARK GeneRIF: This paper states that ECAT1 is not found in rodents. REFERENCE 10 (bases 1 to 1037) AUTHORS Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M and Yamanaka S. TITLE The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells JOURNAL Cell 113 (5), 631-642 (2003) PUBMED 12787504...
Synonym: C6orf221; ECAT1; HYDM2
NM_001017361.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens TARBP2 subunit of RISC loading complex (TARBP2), transcript variant 2, mRNA. (1454 bp)
REMARK GeneRIF: TARBP2 participates in the interaction between IRF7 and TRAF6, thereby suppressing TRAF6-mediated K63-linked ubiquitination of IRF7. REFERENCE 4 (bases 1 to 1454) AUTHORS Lai HH, Li CW, Hong CC, Sun HY, Chiu CF, Ou DL and Chen PS. TITLE TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma JOURNAL Mol Oncol 13 (4), 928-945 (2019) PUBMED 30657254 REMARK GeneRIF: The TARBP2 protein was destabilized through autophagic-lysosomal proteolysis, thereby stabilizing the expression of the cancer stem cell marker protein Nanog, which...
Synonym: LOQS; TRBP; TRBP1; TRBP2
NM_134324.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens SIX homeobox 2 (SIX2), mRNA. (2206 bp)
cell-like phenotype in renal cell carcinoma cells JOURNAL FEBS Open Bio 9 (10), 1808-1816 (2019) PUBMED 31420918 REMARK GeneRIF: The six2 knockdown attenuated the stemness of Renal cell carcinoma (RCC) cells, which was evident by decreased spheroid formation ability and stemness marker (sox2 and nanog) expression. REFERENCE 3 (bases 1 to 2206) AUTHORS Wu Y, Song T, Liu M, He Q, Chen L, Liu Y, Ni D, Liu J, Hu Y, Gu Y, Li Q, Zhou Q and Xie Y. TITLE PPARG Negatively Modulates Six2 in Tumor Formation of Clear Cell Renal Cell Carcinoma JOURNAL DNA Cell Biol. 38 (7), 700-707 (2019) PUBMED 31090452...
NM_016932.5 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens long intergenic non-protein coding RNA 511 (LINC00511), long non-coding RNA. (2265 bp)
and reduces resistance to paclitaxel. REFERENCE 2 (bases 1 to 2265) AUTHORS Lu G, Li Y, Ma Y, Lu J, Chen Y, Jiang Q, Qin Q, Zhao L, Huang Q, Luo Z, Huang S and Wei Z. TITLE Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis JOURNAL J. Exp. Clin. Cancer Res. 37 (1), 289 (2018) PUBMED 30482236 REMARK GeneRIF: Data concludes that LINC00511/miR-185-3p/E2F1/Nanog axis facilitates the breast cancer stemness and tumorigenesis, providing a vital insight for them. Publication Status: Online-Only REFERENCE 3 (bases 1 to 2265)...
Synonym: LCAL5; onco-lncRNA-12
NR_033876.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens heart and neural crest derivatives expressed 1 (HAND1), mRNA. (1701 bp)
overexpression inhibits medulloblastoma metastasis JOURNAL Biochem. Biophys. Res. Commun. 477 (2), 215-221 (2016) PUBMED 27297109 REMARK GeneRIF: Strikingly, human pluripotent stem cell antibody array showed that Hand1 overexpression resulted in substantial decrease in pluripotency markers (Nanog, Oct3/4, Otx2, Flk1) suggesting that Hand1 expression may be essential to attenuate the EMT and our findings underscore a novel role for Hand1 in medulloblastoma metastasis. REFERENCE 4 (bases 1 to 1701) AUTHORS Zhou,Y.M., Dai,X.Y., Qiu,X.B., Yuan,F., Li,R.G., Xu,Y.J., Qu,X.K., Huang,R.T., Xue,S. and...
Synonym: bHLHa27; eHand; Hxt; Thing1
NM_004821.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant 2, mRNA. (1687 bp)
REMARK GeneRIF: Study demonstrated that ZFP57 plays an important role in the hematogenous metastasis of colorectal cancer, suggesting that it could be used as a novel treatment target. The expression level of ZFP57 was significantly correlated with that of the metastasis-related gene NANOG and ZFP57 overexpression reduced the progression-free survival rate of patients with colorectal cancer. REFERENCE 2 (bases 1 to 1687) AUTHORS Chen L, Wu X, Xie H, Yao N, Xia Y, Ma G, Qian M, Ge H, Cui Y, Huang Y, Wang S and Zheng M. TITLE ZFP57 suppress proliferation of breast cancer cells through down-...
Synonym: bA145L22; bA145L22.2; C6orf40; TNDM1; ZNF698
NM_001366333.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens PBX homeobox 1 (PBX1), transcript variant 4, mRNA. (6474 bp)
REMARK GeneRIF: HNRPDL transforms hematopoietic cells and a novel HNRPDL/PBX1 axis plays an important role in human CML CD34(+) cells REFERENCE 2 (bases 1 to 6474) AUTHORS Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, Liu M, Zheng T, Zou F, Liu X, Jin M, Mu Y, Li G, Su G and Liu J. TITLE NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling JOURNAL Oxid Med Cell Longev 2019, 4286213 (2019) PUBMED 31885790 REMARK GeneRIF: Findings show that NANOG delays HF-MSC senescence by upregulating PBX1 and activating AKT signaling and that...
Synonym: CAKUHED
NM_001353130.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens long intergenic non-protein coding RNA, regulator of reprogramming (LINC-ROR), transcript variant 2, long non-coding RNA. (2278 bp)
AI340242.1. Summary: This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017]. Publication Note:...
Synonym: lincRNA-RoR; lincRNA-ST8SIA3; ROR
NR_152602.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens PBX homeobox 1 (PBX1), transcript variant 2, mRNA. (6805 bp)
REMARK GeneRIF: HNRPDL transforms hematopoietic cells and a novel HNRPDL/PBX1 axis plays an important role in human CML CD34(+) cells REFERENCE 2 (bases 1 to 6805) AUTHORS Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, Liu M, Zheng T, Zou F, Liu X, Jin M, Mu Y, Li G, Su G and Liu J. TITLE NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling JOURNAL Oxid Med Cell Longev 2019, 4286213 (2019) PUBMED 31885790 REMARK GeneRIF: Findings show that NANOG delays HF-MSC senescence by upregulating PBX1 and activating AKT signaling and that...
Synonym: CAKUHED
NM_001204961.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens long intergenic non-protein coding RNA, regulator of reprogramming (LINC-ROR), transcript variant 1, long non-coding RNA. (2603 bp)
NR_048536.1. Summary: This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017]. Publication Note...
Synonym: lincRNA-RoR; lincRNA-ST8SIA3; ROR
NR_048536.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens HOX transcript antisense RNA (HOTAIR), transcript variant 3, long non-coding RNA. (2337 bp)
Synonym: HOXAS; HOXC-AS4; HOXC11-AS1; NCRNA00072
NR_047518.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens ZFP57 zinc finger protein (ZFP57), transcript variant 1, mRNA. (2082 bp)
REMARK GeneRIF: Study demonstrated that ZFP57 plays an important role in the hematogenous metastasis of colorectal cancer, suggesting that it could be used as a novel treatment target. The expression level of ZFP57 was significantly correlated with that of the metastasis-related gene NANOG and ZFP57 overexpression reduced the progression-free survival rate of patients with colorectal cancer. REFERENCE 2 (bases 1 to 2082) AUTHORS Chen L, Wu X, Xie H, Yao N, Xia Y, Ma G, Qian M, Ge H, Cui Y, Huang Y, Wang S and Zheng M. TITLE ZFP57 suppress proliferation of breast cancer cells through down-...
Synonym: bA145L22; bA145L22.2; C6orf40; TNDM1; ZNF698
NM_001109809.5 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens nuclear receptor subfamily 5 group A member 2 (NR5A2), transcript variant 2, mRNA. (4831 bp)
was also revealed. Review article Publication Status: Online-Only REFERENCE 3 (bases 1 to 4831) AUTHORS Ye T, Li J, Sun Z, Liu Y, Kong L, Zhou S, Tang J, Wang J and Xing HR. TITLE Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog JOURNAL Cancer Med 8 (3), 1232-1245 (2019) PUBMED 30740909 REMARK GeneRIF: we have provided convincing evidence in vitro and in vivo demonstrating that Nr5a2 can induce lung CSC properties and promote tumorigenesis and progression through transcriptional up-regulation of Nanog. REFERENCE 4 (bases 1 to 4831)...
Synonym: B1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1
NM_003822.5 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens BTB domain and CNC homolog 1 (BACH1), transcript variant t, non-coding RNA. (2778 bp)
Zhang J, Zhang S and Meng D. TITLE Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells JOURNAL Sci Adv 5 (3), eaau7887 (2019) PUBMED 30891497 REMARK GeneRIF: It has been reported that the Usp7 is a direct target of Bach1; that Bach1 interacts with Nanog, Sox2, and Oct4, and that Bach1 facilitates their deubiquitination and stabilization via the recruitment of Usp7, thereby maintaining stem cell identity and self-renewal. Publication Status: Online-Only REFERENCE 3 (bases 1 to 2778) AUTHORS Ou X, Gao G, Bazhabayi M, Zhang K, Liu F and Xiao X....
Synonym: BACH-1; BTBD24
NR_027655.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens PBX homeobox 1 (PBX1), transcript variant 1, mRNA. (7087 bp)
REMARK GeneRIF: HNRPDL transforms hematopoietic cells and a novel HNRPDL/PBX1 axis plays an important role in human CML CD34(+) cells REFERENCE 2 (bases 1 to 7087) AUTHORS Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, Liu M, Zheng T, Zou F, Liu X, Jin M, Mu Y, Li G, Su G and Liu J. TITLE NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling JOURNAL Oxid Med Cell Longev 2019, 4286213 (2019) PUBMED 31885790 REMARK GeneRIF: Findings show that NANOG delays HF-MSC senescence by upregulating PBX1 and activating AKT signaling and that...
Synonym: CAKUHED
NM_002585.4 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens nuclear receptor subfamily 5 group A member 2 (NR5A2), transcript variant 3, mRNA. (4787 bp)
was also revealed. Review article Publication Status: Online-Only REFERENCE 3 (bases 1 to 4787) AUTHORS Ye T, Li J, Sun Z, Liu Y, Kong L, Zhou S, Tang J, Wang J and Xing HR. TITLE Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog JOURNAL Cancer Med 8 (3), 1232-1245 (2019) PUBMED 30740909 REMARK GeneRIF: we have provided convincing evidence in vitro and in vivo demonstrating that Nr5a2 can induce lung CSC properties and promote tumorigenesis and progression through transcriptional up-regulation of Nanog. REFERENCE 4 (bases 1 to 4787)...
Synonym: B1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1
NM_001276464.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens HOX transcript antisense RNA (HOTAIR), transcript variant 1, long non-coding RNA. (2370 bp)
Synonym: HOXAS; HOXC-AS4; HOXC11-AS1; NCRNA00072
NR_047517.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens HOX transcript antisense RNA (HOTAIR), transcript variant 2, long non-coding RNA. (2364 bp)
Synonym: HOXAS; HOXC-AS4; HOXC11-AS1; NCRNA00072
NR_003716.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens nuclear receptor subfamily 5 group A member 2 (NR5A2), transcript variant 1, mRNA. (4969 bp)
was also revealed. Review article Publication Status: Online-Only REFERENCE 3 (bases 1 to 4969) AUTHORS Ye T, Li J, Sun Z, Liu Y, Kong L, Zhou S, Tang J, Wang J and Xing HR. TITLE Nr5a2 promotes cancer stem cell properties and tumorigenesis in nonsmall cell lung cancer by regulating Nanog JOURNAL Cancer Med 8 (3), 1232-1245 (2019) PUBMED 30740909 REMARK GeneRIF: we have provided convincing evidence in vitro and in vivo demonstrating that Nr5a2 can induce lung CSC properties and promote tumorigenesis and progression through transcriptional up-regulation of Nanog. REFERENCE 4 (bases 1 to 4969)...
Synonym: B1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1
NM_205860.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens POU class 5 homeobox 1B (POU5F1B), mRNA. (1386 bp)
transcriptional activator and regulates the expression in a similar way to the POU5F1 isoform 1 REFERENCE 6 (bases 1 to 1386) AUTHORS Firsova,N.V., Markintantova,Iu.V., Smirnova,Iu.A., Panova,I.G., Sukhikh,G.T., Zinov'eva,R.D. and Mitashov,V.I. TITLE [Identification of the OCT4-pg1 retrogene and NANOG gene expression in the human embryonic eye] JOURNAL Izv. Akad. Nauk. Ser. Biol. (2), 134-138 (2008) PUBMED 18946985 REFERENCE 7 (bases 1 to 1386) AUTHORS Suo G, Han J, Wang X, Zhang J, Zhao Y, Zhao Y and Dai J. TITLE Oct4 pseudogenes are transcribed in cancers JOURNAL Biochem. Biophys. Res....
Synonym: OCT4-PG1; OCT4PG1; OTF3C; OTF3P1; POU5F1P1; POU5F1P4; POU5FLC20; POU5FLC8
NM_001159542.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens intercellular adhesion molecule 1 (ICAM1), mRNA. (2967 bp)
also, there was a strong independent association between higher ICAM-1 expression and serum levels with cardiovascular risks in PCOS group. Publication Status: Online-Only REFERENCE 5 (bases 1 to 2967) AUTHORS Saga K, Park J, Nimura K, Kawamura N, Ishibashi A, Nonomura N and Kaneda Y. TITLE NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis JOURNAL J. Exp. Clin. Cancer Res. 38 (1), 416 (2019) PUBMED 31619256 REMARK GeneRIF: Low ICAM1 expression is associated with prostate cancer recurrence Publication Status: Online-Only REFERENCE 6 (bases 1 to 2967)...
Synonym: BB2; CD54; P3.58
NM_000201.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens tudor domain containing 12 (TDRD12), transcript variant 2, mRNA. (1623 bp)
TITLE New loci associated with kidney function and chronic kidney disease JOURNAL Nat. Genet. 42 (5), 376-384 (2010) PUBMED 20383146 REFERENCE 4 (bases 1 to 1623) AUTHORS Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M and Yamanaka S. TITLE The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells JOURNAL Cell 113 (5), 631-642 (2003) PUBMED 12787504...
Synonym: ECAT8
NM_001110822.2 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 2, mRNA. (3414 bp)
tumor microenvironment JOURNAL Oncogene 39 (1), 64-78 (2020) PUBMED 31462709 REMARK GeneRIF: Since cancer stem cells (CSCs) are radioresistant and metastasis-initiating cells, we examined TGLI1 for its involvement in breast CSCs and found TGLI1 to transcriptionally activate stemness genes CD44, Nanog, Sox2, and OCT4 leading to CSC renewal, and TGLI1 outcompetes with GLI1 for binding to target promoters. REFERENCE 2 (bases 1 to 3414) AUTHORS Park SH, Jeong S, Kim BR, Jeong YA, Kim JL, Na YJ, Jo MJ, Yun HK, Kim DY, Kim BG, Lee DH and Oh SC. TITLE Activating CCT2 triggers Gli-1 activation during...
Synonym: GLI; PAPA8; PPD1
NM_001160045.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 3, mRNA. (3483 bp)
tumor microenvironment JOURNAL Oncogene 39 (1), 64-78 (2020) PUBMED 31462709 REMARK GeneRIF: Since cancer stem cells (CSCs) are radioresistant and metastasis-initiating cells, we examined TGLI1 for its involvement in breast CSCs and found TGLI1 to transcriptionally activate stemness genes CD44, Nanog, Sox2, and OCT4 leading to CSC renewal, and TGLI1 outcompetes with GLI1 for binding to target promoters. REFERENCE 2 (bases 1 to 3483) AUTHORS Park SH, Jeong S, Kim BR, Jeong YA, Kim JL, Na YJ, Jo MJ, Yun HK, Kim DY, Kim BG, Lee DH and Oh SC. TITLE Activating CCT2 triggers Gli-1 activation during...
Synonym: GLI; PAPA8; PPD1
NM_001167609.1 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)
Homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 1, mRNA. (3972 bp)
tumor microenvironment JOURNAL Oncogene 39 (1), 64-78 (2020) PUBMED 31462709 REMARK GeneRIF: Since cancer stem cells (CSCs) are radioresistant and metastasis-initiating cells, we examined TGLI1 for its involvement in breast CSCs and found TGLI1 to transcriptionally activate stemness genes CD44, Nanog, Sox2, and OCT4 leading to CSC renewal, and TGLI1 outcompetes with GLI1 for binding to target promoters. REFERENCE 2 (bases 1 to 3972) AUTHORS Park SH, Jeong S, Kim BR, Jeong YA, Kim JL, Na YJ, Jo MJ, Yun HK, Kim DY, Kim BG, Lee DH and Oh SC. TITLE Activating CCT2 triggers Gli-1 activation during...
Synonym: GLI; PAPA8; PPD1
NM_005269.3 - Homo sapiens (human) - NCBI - UCSC - RefEx(expression)

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Redirect URI : http://ggrna.dbcls.jp/hs/nanog
lang : en | div : | spe : hs | query_string : nanog | format : html | download :

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0.077 | 0.077 | count_done; http://172.18.8.71:7700/v1/refseq/query?q=((full_search:*:nanog)%7C(nt:nanog)%7C(aa:nanog))?source=Homo sapiens (human)?to=0&format=json
0.617 | 0.540 | search_done; http://172.18.8.71:7700/v1/refseq/query?q=((full_search:*:nanog)%7C(nt:nanog)%7C(aa:nanog))?source=Homo sapiens (human)?to=49?from=0?snippet=full_search?drilldown=source?get=accession,version,gi,length,symbol,synonym,geneid,division,source,definition&format=json
0.622 | 0.005 | cgi_end;

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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]