LOCUS       NM_203872               2085 bp    mRNA    linear   VRT 13-FEB-2024
DEFINITION  Xenopus tropicalis carnitine O-acetyltransferase b (crat), mRNA.
ACCESSION   NM_203872
VERSION     NM_203872.2
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 2085)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AAMC04000008.1.
            
            On Feb 13, 2024 this sequence version replaced NM_203872.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC063356.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00028290,
                                           SAMD00028291 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG   :: upstream AUG and CDS
                                                  extension is not conserved
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               AAMC04000008.1     73862388-73862521   c
            135-365             AAMC04000008.1     73860052-73860282   c
            366-484             AAMC04000008.1     73856000-73856118   c
            485-538             AAMC04000008.1     73855688-73855741   c
            539-704             AAMC04000008.1     73855427-73855592   c
            705-879             AAMC04000008.1     73854392-73854566   c
            880-1058            AAMC04000008.1     73852675-73852853   c
            1059-1159           AAMC04000008.1     73851254-73851354   c
            1160-1288           AAMC04000008.1     73850893-73851021   c
            1289-1411           AAMC04000008.1     73850014-73850136   c
            1412-1547           AAMC04000008.1     73849702-73849837   c
            1548-1610           AAMC04000008.1     73849208-73849270   c
            1611-1748           AAMC04000008.1     73847654-73847791   c
            1749-2085           AAMC04000008.1     73846929-73847265   c
FEATURES             Location/Qualifiers
     source          1..2085
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="8"
                     /map="8"
     gene            1..2085
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /note="carnitine O-acetyltransferase b"
                     /db_xref="GeneID:394811"
                     /db_xref="Xenbase:XB-GENE-487012"
     exon            1..134
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    57..59
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /note="upstream in-frame stop codon"
     misc_feature    90..92
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     M"
     misc_feature    90..92
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     MMRN"
     CDS             93..1964
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /EC_number="2.3.1.7"
                     /note="carnitine acetyltransferase; carnitine
                     O-acetyltransferase, gene 2"
                     /codon_start=1
                     /product="carnitine O-acetyltransferase b"
                     /protein_id="NP_989203.2"
                     /db_xref="GeneID:394811"
                     /db_xref="Xenbase:XB-GENE-487012"
                     /translation="

MRNMICCRAPLQVMVSFRILSRGYSGSPFPHQPVPDLSKTLFRYLGSLQPLVSKDELESTRELVEEFLRPGGQGEELAKQLQKRAERTDNWLTDWRHQAIYLENHLPLPVHSSPAVLLPQRDHKDWRGQLRFASKLISGVLDFKAKIESPDGLTEIWRGRPLCPHQYHDFFGSCREPGYKRDRVLLQPAHKSLSQYVTVCRNYQFFQMDVYNSDGSPLTEDQIHQQMLFLRAHSYKTDKEPVGVLTTDHRNSWGRAYTTLIRDRLNRESVRSIQRSLFTVCLDATALKYSEELYSSRTAAQMLHGGGTHANSGNRWFDKTLQFVVGEDGTCGLIYDQATADASAILTMLGHVLEYCSRGPKRLPPRTPLTRLPPPKKLYFNFPPETKQHIENAKQNLDILVNDLDICCFTFSDFGKSFPKKHNMRPGAFLQVALQLAYYRCHESLCATCEVVSLRTFHRGRSDVVRCSSSEALEFVQAADEPNRLAGEKLSLLKKAVESHQCATEQVLQGQSVDGTLLALKMLCISSGAALPAILMDTSYAVSSHWKLFTGQVSSPIDCVMCYGPLVPDGYSVCFAPSLDSITVCVSAFDCCQETDAQKLSDSLQGALRDMQSLIIKCQPGEA"

     misc_feature    186..1907
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /note="Choline/Carnitine o-acyltransferase; Region:
                     Carn_acyltransf; pfam00755"
                     /db_xref="CDD:459926"
     misc_feature    93..95
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /note="upstream_AUG_codon; putative N-terminal extension:
                     MRN"
     exon            135..365
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            366..484
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            485..538
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            539..704
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            705..879
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1058
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1159
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1288
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1411
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1547
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1610
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1748
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..2085
                     /gene="crat"
                     /gene_synonym="cat1; crat.2; cratb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ccgtgtcccgcctccgtaactccagctgtaaccttacagccctcggggctagactttagtttgtaccaggagggggggcagctgtcagaatgatgcgaaacatgatctgctgcagagcccccctgcaagtcatggtttccttccgtattctcagcaggggctactctggctctccttttccccatcagcctgtgcctgacctctcaaaaacgctgttccgttacctaggctctctccaacctttggttagcaaagatgaacttgagagcactcgggaactggtggaggaatttctaagacctgggggccagggagaggaactggcaaaacagttacagaagagggctgaaagaactgacaattggctcacagactggagacatcaagctatatacctggagaatcatctgcccctgcctgtgcattctagcccagctgttcttcttccccagagggaccacaaagactggaggggacagctaagatttgcgtccaaactgatttctggggttctggatttcaaagcaaaaattgagagccctgatggtcttacagagatatggagaggtcgtcctctctgtcctcaccaataccatgacttcttcggctcatgcagagaacctggttacaaaagagatcgtgtactgctgcagccggcacataaatccctatctcaatatgtgacagtgtgccgaaattaccagtttttccaaatggatgtatataatagtgatgggtctcctctcactgaggatcagattcatcagcagatgcttttcctgcgagctcactcctacaagacggacaaggagcctgtgggggtgctcaccactgatcaccgaaatagctggggacgtgcatataccacccttatccgggaccgactgaacagagaatctgtgcgcagcatccaacgcagcctcttcacggtctgcctggatgccactgcattgaagtattctgaggagctctatagcagtcgaacagcagcccaaatgctacatggaggggggacacatgcaaatagtggcaacagatggtttgacaaaactttgcagttcgtggttggggaggatggaacatgtggtctgatatatgaccaagcaacagctgatgcctctgctatactaacaatgctgggccatgttctggagtactgctcaagggggcccaaacgccttccacctcgcacacctttaacacgtcttcctcctccaaaaaagctctacttcaatttccccccagaaaccaaacaacacatagaaaatgcaaagcagaaccttgatatattggtgaatgacttagacatttgttgcttcaccttctctgattttgggaagagctttcctaagaaacacaacatgagaccaggtgcttttctgcaggtcgcccttcaactggcatactacaggtgtcatgaatctctttgtgccacatgtgaagttgtcagtctacggacatttcatcgtggtcgttcagatgtagtgcgttgctcttcttctgaggcactggaatttgtgcaagctgcagatgaacccaacagactggctggagagaaactgtcacttttgaaaaaagctgtagagagtcaccagtgtgcaacagaacaggtactgcagggtcagtctgtagatggcactcttcttgctctgaagatgctgtgtatttcctctggagctgctcttcctgccattctcatggatacatcctacgcagtctcttctcattggaagctctttacaggacaggtatcatcccctatagattgtgtgatgtgttatggacctctggttcccgatggctacagcgtctgctttgcaccctccctggacagtattacagtgtgcgtatctgcatttgactgctgtcaggagactgatgcccagaaactatctgacagcctgcaaggggctttaagggacatgcagtctctcatcataaagtgccaaccaggagaggcctaggatcgatatgccttcttgcataaattcctattgctcttgcgatcagacatctgtcattgttgaagatctatatttacattaaaatgtaaccttacttaataaaggttgctttaaaatgaaa

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