LOCUS       NM_001285474            2454 bp    mRNA    linear   VRT 16-JUN-2023
DEFINITION  Xenopus tropicalis POU class 5 homeobox 3, gene 1 (pou5f3), mRNA.
ACCESSION   NM_001285474 XM_002941971
VERSION     NM_001285474.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 2454)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF217105.1, CX487420.2, CX443353.1, CX419491.1, CX501450.1,
            CX461859.1, AL956522.2 and CX481588.1.
            
            On Oct 22, 2013 this sequence version replaced XM_002941971.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CX481589.2, CX443353.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00861986, SAMN00861988
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-680               CF217105.1         37-716
            681-1318            CX487420.2         107-744
            1319-1670           CX443353.1         460-811
            1671-2192           CX419491.1         189-710
            2193-2248           CX501450.1         207-262             c
            2249-2300           CX461859.1         149-200             c
            2301-2447           AL956522.2         380-526
            2448-2454           CX481588.1         2-8                 c
FEATURES             Location/Qualifiers
     source          1..2454
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="8"
                     /map="8"
     gene            1..2454
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /note="POU class 5 homeobox 3, gene 1"
                     /db_xref="GeneID:100498076"
                     /db_xref="Xenbase:XB-GENE-923211"
     exon            1..947
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    270..272
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /note="upstream in-frame stop codon"
     CDS             282..1619
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /codon_start=1
                     /product="POU class 5 homeobox 3, gene 1"
                     /protein_id="NP_001272403.1"
                     /db_xref="GeneID:100498076"
                     /db_xref="Xenbase:XB-GENE-923211"
                     /translation="

MYNQQAYPSFAHPPALMQDGSGQYNVGTYTGMAGHSHQAQAFFPFSGVKSDYGDIGGQTPAVGDNSAPVMGWNPLASLDPANQLGISGQGNPFKGLKREREDEEAKSESPEPKCSPPAAAPYYTHSWNPSSFWSQVSSSGTTIASKPIPIPHQSGDKCDPAGANSIFPSDQSPDKSAESGISSLETSRCSSATSSSSGGTNLGTPRSLSRGASDGLSSDSEEEAPNSGEMEQFAKDLKHKRITMGYTQADVGYALGVLFGKTFSQTTICRFESLQLSFKNMCKLKPLLRSWLHEVENNENLQEIISRGQIIPQVQKRKHRTSIENNVKRTLETYFMQCPKPSAQEIAQIARELNMEKDVVRVWFCNRRQKGKRQVYPYIRENGGEPYDAGQPLIPPSPGPFPLPQVMPSQVPLGPNPAIYLPTYHKNDMFPQAMHHGIAMGNQGN"

     misc_feature    945..1169
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /note="Found in Pit-Oct-Unc transcription factors; Region:
                     POU; smart00352"
                     /db_xref="CDD:197673"
     misc_feature    1230..1400
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            948..1059
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1190
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1355
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..2454
                     /gene="pou5f3"
                     /gene_synonym="Oct-91; oct4; oct79; oct91; oct92;
                     pou5f3.1; XLPOU91; xoct-91; xoct91"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

cttctcccaaatacgcactcacctcagagctggggggcaaacaagagacgagcagggggcctcccaggtaaatgccagggaaccttctcctcccaggccagaactggtgggcgacccatcgctggatggaagagacgcagttaaggacaatttagtcgctgagactggccaggaccccgcaagaagactatgactttctctccaactggtggaagatgccatcgggcttcctaagaccttcccaggtatagagcgatcggcagatttggtaggagccgaccatgtataaccaacaggcctacccttcctttgcccaccccccggccctgatgcaagatggcagcggacagtataatgtgggcacctacactggcatggccgggcacagccaccaagctcaggctttcttccctttctctggggtaaagtcggactatggagacattggggggcaaactcctgcggtgggagataattctgccccagtcatgggctggaaccctctagcttctctggatcctgccaaccagttgggcatctccggccaagggaacccgtttaagggtttaaagagggaaagggaagacgaagaggccaaatcggaatcccctgagcccaaatgcagccctccggccgccgcaccctactatacccactcctggaatccctccagcttctggtcgcaagtctcctcaagtgggaccaccattgcgtccaagcccatacccatcccacaccagtccggtgataaatgtgaccccgctggggcaaatagcatctttccgtccgaccagagccccgacaagtcggcagaaagtggcatctccagcttggagaccagtcgctgtagcagcgccaccagtagctcttctggtgggaccaacttggggacccctagaagcctttctcggggggctagcgacgggctgagcagtgacagtgaggaggaagcccccaattctggggagatggagcagttcgccaaagacctgaagcacaagcgtatcacgatggggtacactcaggcggatgttggctacgcactaggggtgctttttggcaaaacattcagccagaccaccatctgccgcttcgagtccctccagctctcctttaagaacatgtgcaagctcaaacctttgctgcggagttggctccatgaggtggaaaacaacgagaacctccaagaaattatcagcagggggcagataattccccaggtccagaagaggaagcacaggaccagcatcgagaacaacgtgaaacgcaccttggagacctacttcatgcagtgccccaagcccagcgctcaggagatcgctcagattgcgagagagctcaacatggagaaggacgtggtgagagtctggttctgcaaccggcggcagaagggcaagcgccaggtgtacccctatattagggagaatggcggggagccttatgacgccggccaacccttgatacccccctccccaggtccttttccgttaccccaagtgatgccctcccaggtccctctgggtcccaacccagccatctaccttccgacctatcacaaaaacgacatgttcccccaggcaatgcatcatgggatagccatgggtaaccaaggcaactagaccagcccagtctatcctttactctatagttcctttagttttttttttttttgtaccctccggggaccagatttctatgactccctgatcacttcctgttcagcagagcaggaagttgacagtaacttcctgttgaagctgaaggaatgctgtgggctgatagtcctgccttcagttggccccatacaagcttgttaggtgaccccattctattgccagctcagctcgctctatagccccccgactttctcttgccccgccccttttatagatatatattttattgcccctcctgtagctgccctagactataacttatttgccccatctcctagagataccgctatgtgtccctcggacgcgccgcctcgatttgcactcgtgttcattccagcttgtgatttgctctgtgaggtcagctgactgcctgggattccgtcccccgaggagcacgtgatattcatgggggggtctagcactaacccaccaacagttctctttcctacactaatgctgcaaaccccaaagagcattcctcttgtgaatggacagaaatctttatggggggggggggggcatgagtgacccccactgaacccccaaacttttattatggatttttttaagtggggggagttcaataaatgcccccattttgtgccttttgttgagttacagaaatgcattttgtcttctgagtctcaacttttttccttcttttctccttttattgcttttcccacattgtgtgcgttttcactgtccaatgagatccgacgtgtaacggcattggccgattcctgaccaataaaccagaacctgttttataactttg

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