LOCUS       NM_001201422            2078 bp    mRNA    linear   VRT 17-JUN-2018
DEFINITION  Xenopus tropicalis iroquois homeobox 1 (irx1), mRNA.
ACCESSION   NM_001201422 XM_002935127
VERSION     NM_001201422.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 2078)
  AUTHORS   Rodriguez-Seguel E, Alarcon P and Gomez-Skarmeta JL.
  TITLE     The Xenopus Irx genes are essential for neural patterning and
            define the border between prethalamus and thalamus through mutual
            antagonism with the anterior repressors Fezf and Arx
  JOURNAL   Dev. Biol. 329 (2), 258-268 (2009)
   PUBMED   19268445
REFERENCE   2  (bases 1 to 2078)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AAMC03023027.1.
            
            On Jan 21, 2011 this sequence version replaced XM_002935127.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC160569.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1025683, SAMEA1025684
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-627               AAMC03023027.1     127089-127715
            628-1630            AAMC03023027.1     130254-131256
            1631-1700           AAMC03023027.1     131648-131717
            1701-2078           AAMC03023027.1     131814-132191
FEATURES             Location/Qualifiers
     source          1..2078
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="6"
                     /map="6"
     gene            1..2078
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /note="iroquois homeobox 1"
                     /db_xref="GeneID:100038208"
                     /db_xref="Xenbase:XB-GENE-486817"
     exon            1..627
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /inference="alignment:Splign:2.0.8"
     CDS             355..1758
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /note="Iroquois homeobox protein 1"
                     /codon_start=1
                     /product="iroquois-class homeodomain protein irx-1"
                     /protein_id="NP_001188351.1"
                     /db_xref="GeneID:100038208"
                     /db_xref="Xenbase:XB-GENE-486817"
                     /translation="

MSFPQLGYPQYLSAGQAAVYGGERPGVLAAAAAAAAAAAAAGSGRPTGADLGSSSTAAVTSVLGMYASPYSAPNYSAFLPYTTDLTLFSQMGSQYELKDNPGVHPATFAAHTTPGYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKEDDNIFGSDTEGDHEKNEDDEEIDLESIDIDKIDDNDGEQSNEEEDEKLEHLRQGEKESFKKESEVMIPSSDGLKSKDSLSLGKESSDTSNTRIVSPGGQGNIQVPPHNKPKIWSLAETATSPDGALKSSPPPSQANHTSPPIQHPAFLPSHGLYTCQIGKFHNWTNGAFLTQSSLINMRSLLGVNPHHVAHHNHHHLQAHQQAPLLATNLSSLSSDKTPERTSPKHSDRENLPRTESPPQLKPSFQAVRENTLSQQEGTSRILTALPSA"

     misc_feature    787..903
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /note="Homeobox KN domain; Region: Homeobox_KN; pfam05920"
                     /db_xref="CDD:428673"
     misc_feature    1261..1314
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /note="Motif in Iroquois-class homeodomain proteins
                     (only). Unknown function; Region: IRO; smart00548"
                     /db_xref="CDD:214716"
     exon            628..1630
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /inference="alignment:Splign:2.0.8"
     exon            1631..1700
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /inference="alignment:Splign:2.0.8"
     exon            1701..2078
                     /gene="irx1"
                     /gene_synonym="iro; iro1; irx-5; irx1-a; irx1-b; Xiro;
                     Xiro1"
                     /inference="alignment:Splign:2.0.8"
ORIGIN      

tcagcccaggacctaagggcagacacatcagttggagctcaattgttgatcagatcacatctaagggatttagaagcacagaagagcagagatttgagggggctaaaaaacacactgagacaccctaacgaatccacacacctcgtccctttctctcatccgagctccctctgtacaacgcgcacagtgggagagggactccgcttctactgctcactttttggccccgtccttgaccaattcgctcttttttttttatttagatcagtttttacctcccctttaagatacatttcttctctcctgtacttgctgttgtgcgcggagtggcagcgatttccctgccggagagacatgtccttccctcagctgggctacccccagtacctgagcgctggccaggctgcagtctatggaggcgaacggccgggtgttttggccgcggcagcggcagcagcggccgcagcagcagcagccggatccggaaggccgacaggagctgatctgggcagcagttctaccgcggcagtgacctcagtgctgggcatgtatgccagcccctacagcgctcccaactacagcgcctttctaccctacaccaccgatctcacccttttctcccaaatgggatcgcagtatgaactgaaagacaaccccggtgtccacccagccacatttgctgcacacactactccaggctattacccctatggacagttccaatacggagacccagggcggcccaagaatgccaccagggagagcaccagtaccctaaaggcttggctcaatgagcacaggaagaacccttaccccaccaagggggagaagatcatgctggccataatcaccaagatgaccctcacccaggtctcaacgtggtttgcaaacgctcggaggaggctaaagaaggagaataaggtcacttggggggcaaggagtaaggaagatgacaacatctttgggagtgatactgaaggagaccatgaaaaaaatgaagatgacgaggaaatagatttggaaagcatagatattgataaaattgatgacaacgacggtgagcaaagcaatgaggaagaggatgagaaactggagcacttgagacagggcgagaaagagagtttcaaaaaggagagtgaagtgatgattccaagttccgacggacttaaatcaaaagactcattgtcccttggtaaggaaagttctgataccagcaataccagaatagtaagccccggtgggcagggcaacatacaagtgccacctcacaataaaccaaaaatctggtccttggcagaaacagcaacaagtccagatggggccttgaagtcttctcctccaccttctcaagccaatcacacatctcccccaattcagcacccagcctttctccccagccatggactatacacatgccaaattggcaaatttcacaactggacaaacggggcctttctcacacagagctccctgataaacatgaggtccttgctgggagtaaaccctcaccatgtggctcaccataaccaccatcaccttcaggctcaccaacaagctccattgttagcaacaaacctgagttccctcagcagcgacaaaactccagaacggaccagccccaagcactcagacagagaaaacttacccagaaccgaatctccacctcagttaaaaccttccttccaagctgttcgtgaaaacaccctttcacagcaagaaggcacctctcgtatattgacagcacttccctctgcctgactgctagaaggaacgattaaaagagaccttaccaaaatatggacacaaatgggtatcttataaatgactcctaccctctttttgcaataatgtgctacacattcagactatcgaatttttctaggcggatttccctctttccgtgttccatttcagaacgtgtaaaactaaccctgatcggatattttttatgtttcccaagtatttgtgttttttttctctctgtatataaagtgatctcagattgtaaatagcgcgcaagcaagaacttgtctaaatcatatatttttgtctaataaactaaatgaaattatgaaaaa

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