LOCUS       NM_001114235            1074 bp    mRNA    linear   VRT 16-JUN-2023
DEFINITION  Xenopus tropicalis VENT homeobox 1 gene 1 (ventx1), mRNA.
ACCESSION   NM_001114235
VERSION     NM_001114235.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Kumar S, Umair Z, Kumar V, Lee U, Choi SC and Kim J.
  TITLE     Ventx1.1 competes with a transcriptional activator Xcad2 to
            regulate negatively its own expression
  JOURNAL   BMB Rep 52 (6), 403-408 (2019)
   PUBMED   31068250
  REMARK    GeneRIF: Results suggest that Ventx1.1 negatively regulates its own
            transcription in competition with Xcad2, thereby fine-tuning its
            own expression levels during dorsoventral patterning of Xenopus
            early embryo.
REFERENCE   2  (bases 1 to 1074)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158394.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158394.1, CX468029.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00861988, SAMN00862006
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="7"
                     /map="7"
     gene            1..1074
                     /gene="ventx1"
                     /gene_synonym="PV.1; ventx1.1; ventx1.1-a; ventx1.1-b;
                     Xvent-1b"
                     /note="VENT homeobox 1 gene 1"
                     /db_xref="GeneID:100101668"
                     /db_xref="Xenbase:XB-GENE-920501"
     exon            1..284
                     /gene="ventx1"
                     /gene_synonym="PV.1; ventx1.1; ventx1.1-a; ventx1.1-b;
                     Xvent-1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..871
                     /gene="ventx1"
                     /gene_synonym="PV.1; ventx1.1; ventx1.1-a; ventx1.1-b;
                     Xvent-1b"
                     /note="posterior-ventral 1"
                     /codon_start=1
                     /product="VENT homeobox 1 gene 1"
                     /protein_id="NP_001107707.1"
                     /db_xref="GeneID:100101668"
                     /db_xref="Xenbase:XB-GENE-920501"
                     /translation="

MVQQGFSIDLILARNREEAPDGKDSVSSRPHIPCAPQPLAPTKYAKEIPRRKDGQEQGDATSFQSSLGKHGDKLHYSSPSSAALHRNWGSSDEFSSAGSEDDSTDGFPSPVRNSQETETDCRGKSPKSDLQRRLRTAFTPQISRLEQAFNKQRYLGASERKKLATSLRLSEIQVKTWFQNRRMKLKRQIQDQQHSMVPPPVCYPQTFSYYPGGLPVPLNSGSFFQPPAHPFQTPQHSYIPDPRFIPQTLPHHVRMSSSLQEQYSPLFGAQYMGAMAQ"

     misc_feature    431..598
                     /gene="ventx1"
                     /gene_synonym="PV.1; ventx1.1; ventx1.1-a; ventx1.1-b;
                     Xvent-1b"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            285..556
                     /gene="ventx1"
                     /gene_synonym="PV.1; ventx1.1; ventx1.1-a; ventx1.1-b;
                     Xvent-1b"
                     /inference="alignment:Splign:2.1.0"
     exon            557..1057
                     /gene="ventx1"
                     /gene_synonym="PV.1; ventx1.1; ventx1.1-a; ventx1.1-b;
                     Xvent-1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ctctaaaggctccaaccagagcagggttcccttcagcatggttcaacagggattctctattgacctcattctagcaaggaatagagaggaggcaccagatggaaaggactcagtaagctccaggccccacataccttgtgccccacaaccactggccccaaccaagtatgccaaggagataccaaggagaaaggatggacaagaacaaggagatgccaccagcttccagagctccttagggaaacatggggacaagctgcattattctagtccttcctcagctgctttgcacaggaattgggggagctcggatgaattctcgtcggctggttcagaagatgacagtaccgacggttttcccagcccagtaagaaattcccaagaaactgagactgactgcagggggaaaagtcctaaatctgatctccagcgcagactgagaacggcattcaccccccagatcagcagactggaacaggcattcaataagcagagataccttggggcatctgaaaggaagaagctggcaacatctctccggctctcagaaatacaggttaaaacctggttccagaaccgaaggatgaaactgaagaggcagatacaagaccagcagcacagcatggttcctccgccagtctgttacccccagaccttctcttattaccctggtggccttcctgtcccattaaacagtggaagtttttttcagcccccggcacatccattccagacaccacagcattcatatattccagatccacgctttattccgcagacactcccccaccatgttaggatgagcagttctctccaggaacaatattcaccactctttggtgctcagtacatgggagctatggctcagtaacagaactcggttttagtgggctttgttgtttaacttatgtagtataactattttatatacatttgtaaatagctgatatataatttaattaatgtaatgtaagtaatgtatatagttttgcttgtacagtaaattgaaatcttttttttttttaagaaaattcagtaaatatgaggtataatttggaaaaaaaaaaaaaaaaa

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