LOCUS       NM_001100260            1906 bp    mRNA    linear   VRT 29-OCT-2016
DEFINITION  Xenopus tropicalis one cut homeobox 1 (onecut1), mRNA.
ACCESSION   NM_001100260
VERSION     NM_001100260.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 1906)
  AUTHORS   Haworth KE and Latinkic B.
  TITLE     Expression of Xenopus tropicalis HNF6/Onecut-1
  JOURNAL   Int. J. Dev. Biol. 53 (1), 159-162 (2009)
   PUBMED   19123138
  REMARK    GeneRIF: Expression of the Xenopus tropicalis Onecut-1/HNF6 gene
            was found to be conserved in the neural tube, the sensory placodes
            and in the anterior ventral endoderm in a domain consistent with
            the developing liver primordium
REFERENCE   2  (bases 1 to 1906)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC135775.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC135775.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1025686, SAMEA1025687
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1906              BC135775.1         25-1930
FEATURES             Location/Qualifiers
     source          1..1906
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="3"
                     /map="3"
     gene            1..1906
                     /gene="onecut1"
                     /gene_synonym="hnf-6; hnf6; hnf6a"
                     /note="one cut homeobox 1"
                     /db_xref="GeneID:100101763"
                     /db_xref="Xenbase:XB-GENE-480152"
     misc_feature    82..84
                     /gene="onecut1"
                     /gene_synonym="hnf-6; hnf6; hnf6a"
                     /note="upstream in-frame stop codon"
     CDS             217..1698
                     /gene="onecut1"
                     /gene_synonym="hnf-6; hnf6; hnf6a"
                     /note="one cut domain, family member 1"
                     /codon_start=1
                     /product="hepatocyte nuclear factor 6"
                     /protein_id="NP_001093730.1"
                     /db_xref="GeneID:100101763"
                     /db_xref="Xenbase:XB-GENE-480152"
                     /translation="

MNAQLTMDAIGDLHGISHESVPGTADLMGSSPHHRGSVTHRSNHLSAHPRSMGMASILDGGDYHHHHHHHHRPPDHALTGPLHPTMTMACDTPPGMSMSSTYTTLTPLQPLPPISTVSDKFPHHHHHHHPHQRIPGNVSGSFTLMRDDRGLASMNNLYSPYHKEVTGMGQSLSPLSGSGLGSIHGAQQGPPHYAHPSAAMPTEKMLTPNGFEAHHPAMLTRHGEQHLTPPSAGMVPINGIPHHPHAHLNAQSHGQILASTRDQNPPSVTGSQINNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAALVPADPVFQHSGQLPADSLVKIGYPSQSTQSNHMSCKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGNSGSGNTSSSSSTCTKA"

     misc_feature    1057..1281
                     /gene="onecut1"
                     /gene_synonym="hnf-6; hnf6; hnf6a"
                     /note="CUT domain; Region: CUT; pfam02376"
                     /db_xref="CDD:460543"
     misc_feature    1453..1620
                     /gene="onecut1"
                     /gene_synonym="hnf-6; hnf6; hnf6a"
                     /note="Homeodomain; Region: HOX; smart00389"
                     /db_xref="CDD:197696"
     misc_feature    order(1456..1470,1474..1476,1525..1527,1543..1545,
                     1582..1584,1588..1593,1600..1605,1609..1617)
                     /gene="onecut1"
                     /gene_synonym="hnf-6; hnf6; hnf6a"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(1462..1464,1471..1473,1591..1593,1600..1605,
                     1612..1614)
                     /gene="onecut1"
                     /gene_synonym="hnf-6; hnf6; hnf6a"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
ORIGIN      

ggcgagtgcaacgagcaggctccaatcgttgctgctgctgctgctgctctgacaaaggggatcgggccttccagttgcatttagacaataccatcggctacatcagtaggaataagatctgggagcttgagcgggatccaatgcccacaagtgccgggacttttgcccagcagcacgccagatagatgtgcgctttactcgcctgtacgttccatcatgaacgctcagctgactatggacgcgattggcgatctgcacgggataagccatgagtcggtgccaggcacagctgatctgatgggcagcagcccccaccacaggggctcagtcacccaccggagcaaccatctgtccgctcaccccaggtccatgggcatggcttccattctcgatggaggggactatcaccaccaccaccaccaccaccacagaccccccgatcacgcattaacggggccactgcaccccactatgaccatggcttgcgatacccctcccgggatgagtatgagcagcacatacaccacgctaacccctctgcagcctttacccccaatctctacagtgtcggacaaattcccccatcaccatcatcaccatcacccccaccagcggataccgggcaatgtcagtggcagcttcaccctaatgagggacgataggggactggcgtctatgaacaatctttacagcccctaccacaaggaggtcaccggcatggggcagagtctgtccccgctctcgggatctggtcttgggagcatccacggtgcccagcaggggccgccccactatgcccatcccagtgccgccatgcccaccgagaaaatgcttaccccgaatggctttgaagcccaccatcctgccatgttgacaaggcacggagagcaacatcttacccctccatcagctggcatggtgcctattaatgggataccccatcaccctcatgcccatttaaatgcccaaagccacggacagattctggcctccaccagggatcaaaatcctccttctgtgactggatcacaaatcaacaatggaagtaattcagggcaaatggaagaaatcaataccaaagaagtcgctcagagaatcacaaccgagctaaagcgctatagtatcccccaggcgatctttgcccagcgggttctgtgccgctctcaagggaccctgtcagacctgctgaggaaccccaagccttggagcaagctcaagtccggccgcgaaaccttccgaaggatgtggaagtggctgcaggagcccgagttccagagaatgtcagctcttaggcttgcagctttggtaccagccgatccggtatttcagcactctggacagttgcctgcagactccctggttaaaatcggctatccatcacaaagcacccagtctaatcacatgtcatgcaaacggaaagaacaagaacatggaaaagacagagggaacacaccaaaaaagccaaggttggtcttcacagatgtccaacgcagaactctccatgcaatatttaaagaaaataagcgtccatccaaagagttacaaatcaccatttcccagcagctaggcctggagctcagcacagtcagtaattttttcatgaatgctcgcaggaggagtcttgataagtggcaggatgagggaaactctgggtctggcaacacatcatcttcatcaagcacttgtaccaaagcatgaagggaaacacacaaaccccagaaactgaaacctcggtggaaaagctttaatacaaagaccaggacctcagcttagtaggtttatactttagaactatttgaaaccaaaataatttataagtccaaagaaaccaaagactcatttctcctggtgacttttattcttaagacattttttcaggagaacgacttgcaaaaaaaaaaaaaaa

//