LOCUS       NM_001100228            2649 bp    mRNA    linear   VRT 14-OCT-2022
DEFINITION  Xenopus tropicalis LIM homeobox 1 (lhx1), mRNA.
ACCESSION   NM_001100228
VERSION     NM_001100228.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 2649)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2649)
  AUTHORS   Rana AA, Collart C, Gilchrist MJ and Smith JC.
  TITLE     Defining synphenotype groups in Xenopus tropicalis by use of
            antisense morpholino oligonucleotides
  JOURNAL   PLoS Genet 2 (11), e193 (2006)
   PUBMED   17112317
REFERENCE   3  (bases 1 to 2649)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC135731.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC135731.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2649
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="2"
                     /map="2"
     gene            1..2649
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /note="LIM homeobox 1"
                     /db_xref="GeneID:100101708"
                     /db_xref="Xenbase:XB-GENE-482482"
     exon            1..785
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    604..606
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /note="upstream in-frame stop codon"
     CDS             616..1845
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /codon_start=1
                     /product="LIM/homeobox protein Lhx1"
                     /protein_id="NP_001093698.1"
                     /db_xref="GeneID:100101708"
                     /db_xref="Xenbase:XB-GENE-482482"
                     /translation="

MVHCAGCERPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLNNNNNNNNAAKENSFISVTGSDPSLSPESQDPLQDDAKDSESANISDKEAGVNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGSNYDFFPQGPPSSQAQTPVDLPFVPSSGPAGTPLGAMDHPIPGHHPSSDAQRFTDIMSHPPGDSPSPEPNLPGSMHSMSAEVFGQSPPFSSLSVNGAAGYGNHLSHPPEMNETAVW"

     misc_feature    625..780
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /note="The first LIM domain of Lhx1 (also known as Lim1)
                     and Lhx5; Region: LIM1_Lhx1_Lhx5; cd09367"
                     /db_xref="CDD:188753"
     misc_feature    order(625..627,634..636,688..690,697..699,706..708,
                     715..717,766..768,775..777)
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188753"
     misc_feature    802..969
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /note="The second LIM domain of Lhx1 (also known as Lim1)
                     and Lhx5; Region: LIM2_Lhx1_Lhx5; cd09375"
                     /db_xref="CDD:188761"
     misc_feature    order(802..804,811..813,868..870,877..879,886..888,
                     895..897,955..957,964..966)
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188761"
     misc_feature    1165..1335
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            786..1024
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1299
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1465
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..2647
                     /gene="lhx1"
                     /gene_synonym="lim-1; lim1; Xlim-1; Xlim1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gacagttcggatgggaagagccagtctgtggagcaaacctgtaggatcgccagctccagtgccagcttctcagcaacctgcaccacagccaagggatcgctctctgcattggcaccgtagatgctcacgggggattccttcattcatcgactttgttcagcagctagtgggatttggacaataaagccaggggcagaagttgttgatgggctaggggacttccttggtgacgttaagtgagaacgggcaaaggaatcagcccccgggataccaagaggagtgggaagaaaaggaaaattatttaactgcaagccgaaccaacggcccgaggtgtgtttgtggagcctgtccgtggcgctggacgtgatgccgggcaacctaaatccccttggcttgtaatttctatagccaaacagatgcactttcagcattgactgcgctacctcagagccagaaggcaactgatcgccccacatctctgccctctcctacctcctgctaccttggcttggggatctccatcagctccgtctgcttgtctttctggaccatagtgtctgccttctgtcctcctaacccgtccccttcctttaaaatcccaaataaccaaagacaatggttcactgtgctggatgcgaaaggcccattctggatcgtttcttgttgaatgtgctggacagggcttggcatgtgaaatgcgtgcagtgctgcgagtgtaagtgcaatctgaccgagaaatgcttctccagggagggcaagctctactgcaaaaacgacttcttcaggcgctttggtaccaagtgtgcgggctgtgcccaggggatctcccccagtgacctagtcaggagggcaaggagcaaagtgtttcacttgaactgtttcacctgtatgatgtgtaacaaacagctctccactggagaggaactttatatcatcgatgagaataagtttgtctgcaaagaagattacttaaacaacaacaacaacaacaacaacgctgccaaagaaaacagctttatctcagtaacaggcagtgaccccagtttatctcctgaatctcaagacccgctgcaagatgacgctaaagactctgaaagtgccaatatctctgataaggaggctggggttaatgaaaacgacgaccaaaaccttggggcgaaaagaaggggacctaggaccactatcaaagccaaacagctggagaccctgaaagcagcttttgcagctacaccaaaaccgacccggcacataagggagcagctggcacaggagactggtctcaacatgcgagtcatccaggtctggttccagaaccgacgatccaaagagagaagaatgaaacagctgagcgctctgggggcccgcagacacgccttcttccgcagcccccgaaggatgaggccgctggtggacaggttagagccgggggaactcatccccaatggacccttctccttctatggagattatcagagtgagtattatggccctggcagcaactatgactttttcccacaaggacccccatcatctcaagctcagactcctgtagatttgccatttgttccttcttctgggcctgcaggaactccacttggtgcaatggatcacccaatccctggacaccacccatctagtgacgctcagaggtttactgacataatgtcccacccaccaggagactctccaagcccagagcccaatctaccaggttccatgcactctatgtctgcagaagtgtttggtcaaagtccccccttttcttctctatcggtcaatggagcagcaggttatggcaaccatttgtcacacccgccagaaatgaacgaaactgcagtgtggtagcctaagttggacaaaaacagaaacaaaaaatcagaaaggactgggtgcaatgggctaccatgtcaacgtttcctatgaaaataacgtggtgtacagaactggtaaataaaattatattctgtcctaaaggtgtgtacagttttggatggaaaaaaaataatttgcaagaatatgccataatatggattcaaagaaaaaaatattttctaagatgacagaaaaatcaaactggtgacgctgtaaagtagagttttgtcatgctaggggatggaaaagaatagcctggtaggtggtacacaggacacaatataaatctgctttcattgtacacacagtacacctaagtgcaagtgataatcttgaaggactccataggaaaaaaaataccttatcaagaattgcctagaatgttgagtctgtctagaatgttgagctttctcttccttggagaaatgtactgtagccagactgttttagcttcagacacgcacctgtatattcaggtgcgacacaacatttgccaaaataacaaaatacaacaatgtaaacccctcagcatcaactattctaccttcacaaagctactcacacgaaaaaataaaatcctcattatgaaggtctgttggaagacctggaaggagacttgaaacaaaaaatagattctaccttcactaacaatgaaataaaatgactatggaactataagcagtcaactgtttacgtctgacgtcaaattcaggagcctaatgttttagtaataatcctgttttagaaacctctttgttcaaaaaaaaaaaaaaaaaa

//