LOCUS       NM_001004887            2019 bp    mRNA    linear   VRT 22-JUN-2025
DEFINITION  Xenopus tropicalis albumin (alb), mRNA.
ACCESSION   NM_001004887
VERSION     NM_001004887.2
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC090362.1.
            
            On Oct 5, 2010 this sequence version replaced NM_001004887.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090362.1, BC075287.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01758127, SAMN06679846
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="1"
                     /map="1"
     gene            1..2019
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="albumin"
                     /db_xref="GeneID:448227"
                     /db_xref="Xenbase:XB-GENE-480330"
     exon            1..97
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..1848
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /EC_number="6.1.1.16"
                     /note="serum albumin"
                     /codon_start=1
                     /product="albumin precursor"
                     /protein_id="NP_001004887.2"
                     /db_xref="GeneID:448227"
                     /db_xref="Xenbase:XB-GENE-480330"
                     /translation="

MKWITLICLLISSSLIESRIILKRDADQDHQKHIADVFNELTERTFKGLTLAIVSQNLQKCSLEELSKLVNEITDFAKSCTGNDKTPECDKKIDTLFYDKLCADPKVGVNYEWTKDCCSKQDPERGECFREHRDVEHTPVKTLSPEQTCTLFKEHPDDLLSVFIHEEARHHPDLYPPAVLLLTKQYQKTVEHCCEEEDKEQCFKEKIKEIMKQTHSIQDTQKHFCWILDTHKERALKAINLARVSHRYPKSDFKLAHTFTEEITHFIKDCCHGDMFECMSERMELSKHTCDHKDELSSKLGKCCDLPVLERSYCIVTLENDEVPAELSKPITEFTEDPHVCEKYAENQEVFLGRYLHAVSRKHQELSKEFLVQSAKEYETLLNKCCKTDNPPDCYKDAANLFLNEAKERFAYLKQNCDALQEHGEYLFENDALIRYAKKMPTVSSKGLIGLAHQMADIGEHCCALPENQRLPCAEGDLSILFGKLCEKQKKNFANDGVAHCCSDSYSGMRSCFTALGPDTNYVPPPVTDDTFHFDDKICTANEKEQQHIKQTFLVKLIQVSPKMEKNHIDECSAEFLKMVQKCCTADEHQGCFDTEKKPLIEHCQKLHP"

     sig_peptide     19..72
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
     misc_feature    100..633
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="serum albumin; Region: ALBUMIN; smart00103"
                     /db_xref="CDD:214517"
     misc_feature    order(178..180,190..192,235..237,298..300,310..312,
                     319..321,394..396,403..408)
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="binding site"
                     /db_xref="CDD:237982"
     misc_feature    order(496..498,505..510,517..519,565..567,574..576)
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="binding site"
                     /db_xref="CDD:237982"
     misc_feature    661..1209
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="serum albumin; Region: ALBUMIN; smart00103"
                     /db_xref="CDD:214517"
     misc_feature    order(748..750,760..762,805..807,862..864,874..876,
                     883..885,952..954,961..966)
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="binding site"
                     /db_xref="CDD:237982"
     misc_feature    order(1072..1074,1081..1086,1093..1095,1141..1143,
                     1150..1152)
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="binding site"
                     /db_xref="CDD:237982"
     misc_feature    1258..1818
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="Albumin domain, contains five or six internal
                     disulphide bonds; albuminoid superfamily includes
                     alpha-fetoprotein which binds various cations, fatty acids
                     and bilirubin; vitamin D-binding protein which binds to
                     vitamin D, its metabolites, and fatty acids; Region:
                     ALBUMIN; cd00015"
                     /db_xref="CDD:237982"
     misc_feature    order(1324..1326,1336..1338,1381..1383,1450..1452,
                     1462..1464,1471..1473,1546..1548,1555..1560)
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="binding site"
                     /db_xref="CDD:237982"
     misc_feature    order(1666..1668,1675..1680,1687..1689,1735..1737,
                     1744..1746)
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /note="binding site"
                     /db_xref="CDD:237982"
     exon            98..164
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            165..297
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            298..503
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            504..636
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            637..734
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            735..864
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            865..1079
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1212
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1310
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1449
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1673
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1806
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..1861
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..1989
                     /gene="alb"
                     /gene_synonym="alb-a; alb-b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

cccaatacacctccagtcatgaagtggatcacccttatttgtctgttaattagctcctcgttaattgaatcaaggattattttaaaaagagatgcagatcaagaccatcaaaagcatatcgctgatgtgttcaatgaattgaccgagcggaccttcaaaggacttacattggctattgtctcacagaatctccagaaatgttcattggaggagctttctaaactggtgaatgaaattactgactttgccaagagctgtacaggaaatgataaaactccagagtgtgacaaaaaaattgataccctgttttatgacaaactctgtgcagatccaaaggtgggtgttaactatgagtggaccaaagattgctgttctaagcaagatccagagagaggagagtgcttcagggagcacagagatgttgaacatactccggtaaagactttatcacctgagcaaacttgcacgttgttcaaagaacaccctgatgaccttctctcagtgttcatccatgaggaggcaagacaccatccagacctttatcctccagcagtactattattaactaagcaatatcagaaaactgttgaacattgttgtgaagaagaagacaaggaacaatgcttcaaagaaaagattaaggaaattatgaaacaaactcattccattcaagatacacaaaaacatttctgctggattctggatactcataaagaaagagcacttaaagcaataaatttggccagagtgagccatagatatcctaagtctgacttcaagcttgcccatacatttactgaggagataacacattttattaaggattgttgtcatggggacatgtttgaatgcatgtctgagaggatggagctttctaagcacacctgtgaccataaagatgagttatcatccaaattaggaaaatgctgtgatctaccagtgctggagcgttcatactgcatcgtcaccttggaaaatgatgaagttcctgctgaattatctaaaccaattacagaatttacagaggacccacacgtgtgtgagaagtatgctgagaatcaagaggttttcttgggcagatatctccatgctgtgtcaagaaaacaccaggaattgtctaaagaattccttgtgcaatctgcaaaagaatatgaaactttgcttaacaagtgctgcaaaacagacaatcctcctgactgctacaaggatgcagctaacttgttcttaaatgaagccaaggagagatttgcatatttgaaacaaaactgtgatgctctgcaagaacatggtgaatacctttttgaaaatgacgctcttataaggtacgccaagaaaatgcccacagtatcaagtaaaggtttgattggattagcacaccaaatggcagatattggtgaacactgctgtgccctaccagaaaaccagaggttgccatgtgcagaaggagaccttagcatactctttggaaagctgtgtgaaaagcaaaagaagaattttgcaaatgatggagttgctcactgctgcagtgactcgtattctgggatgcgttcatgctttactgctcttggtccggatacgaactatgtaccacccccagtcactgatgacacatttcacttcgatgacaagatatgcactgctaatgagaaagaacaacagcatatcaaacagacattccttgtgaaactgattcaagtcagtccaaaaatggagaaaaatcacattgatgaatgttctgctgaattccttaagatggttcagaaatgctgtactgcagatgaacaccaggggtgctttgatacagagaaaaaaccactgattgaacactgtcaaaaactccatccataagagcaaaggccagccttcaaactgaccaaggaagatcttccatctctcaaacacagaaaaaagttttcttcagctgaaaatgaacatttgctcagagcattcatctgtttgttgcaataaataaagcgtttaaaaaaaataaaaaaaaaaaaaaaaaaaaaaaaaaaaagg

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