..... linear PRI 27-JAN-2013 DEFINITION Homo sapiens claudin 25 (CLDN25), mRNA. ACCESSION NM_001101389 ..... 690) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... gastric cancer, is a novel member of CLAUDIN gene family JOURNAL Int. J. Mol. Med. 11 (6), ..... Summary: This gene encodes a member of the claudin family. ..... Claudins are integral membrane proteins and components of ..... /map="11q23.2" gene 1..690 /gene="CLDN25" /note="claudin 25" /db_xref="GeneID:644672" .....

..... linear PRI 23-MAR-2013 DEFINITION Homo sapiens claudin 22 (CLDN22), mRNA. ACCESSION NM_001111319 ..... 2708) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... gastric cancer, is a novel member of CLAUDIN gene family JOURNAL Int. J. Mol. Med. 11 (6), ..... 1 to 2708) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: This gene .....

..... linear PRI 24-MAR-2013 DEFINITION Homo sapiens claudin 9 (CLDN9), mRNA. ACCESSION NM_020982 XM_001715692 ..... Montano,L.F. and Rendon-Huerta,E.P. TITLE Claudin-6, 7, or 9 overexpression in the human gastric ..... 20874001 REMARK GeneRIF: Increased expression of claudin-6, ..... claudin-7, or ..... claudin-9 is sufficient to enhance tumorigenic properties ..... TITLE Distribution and expression pattern of claudins 6, 7, and 9 in diffuse- and intestinal-type ..... (1), 52-59 (2010) PUBMED 19960275 REMARK GeneRIF: Claudins 6, 7, and 9 expressions are closely related to ..... Wangemann,P., Nessler,R.A. and Banfi,B. TITLE A claudin .....

..... linear PRI 14-APR-2013 DEFINITION Homo sapiens claudin 20 (CLDN20), mRNA. ACCESSION NM_001001346 VERSION ..... 1209) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... Ahlstrom,R. and Yu,A.S. TITLE Biology of claudins JOURNAL Am. J. Physiol. Renal Physiol. 295 (4), ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... 1 to 1209) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: .....

..... linear PRI 14-APR-2013 DEFINITION Homo sapiens claudin 3 (CLDN3), mRNA. ACCESSION NM_001306 VERSION ..... Lin,X., Manorek,G. and Howell,S.B. TITLE Claudin-3 and ..... claudin-4 regulate sensitivity to cisplatin by ..... (1), 85-94 (2013) PUBMED 23053666 REMARK GeneRIF: Claudin-3(CLDN3) and ..... claudin-4 (CLDN4) affect sensitivity of the ovarian ..... and Howell,S.B. TITLE Tight junction proteins claudin-3 and ..... claudin-4 control tumor growth and metastases JOURNAL ..... Matsumoto,T. and Miwa,H. TITLE Down-regulation of claudin-3 is associated with proliferative potential in ..... PUBMED 22290341 REMARK GeneRIF: Dow-regulati .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 17 (CLDN17), mRNA. ACCESSION NM_012131 VERSION ..... 731) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... 1 to 731) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: This gene encodes a member of the claudin family. ..... Claudins are integral membrane .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 18 (CLDN18), transcript variant 1, mRNA. ..... Ishikawa,S., Kokudo,N. and Fukayama,M. TITLE Claudin-18 is an early-stage marker of pancreatic ..... 942-952 (2011) PUBMED 21832145 REMARK GeneRIF: Claudin 18 (a marker for early carcinogenesis) is ..... the protein kinase C pathway might be involved in claudin 18 expression associated with carcinogenesis. ..... Aoki,T., Kokudo,N. and Fukayama,M. TITLE Claudin-18 in biliary neoplasms. Its significance in the ..... and Sawada,N. TITLE Transcriptional regulation of claudin-18 via specific protein kinase C signaling ..... Park,S.W. TITLE Immunohistochemical analysis .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 11 (CLDN11), transcript variant 2, mRNA. ..... TITLE Expression pattern of testicular claudin-11 in infertile men JOURNAL Urology 80 (5), 1161 ..... 22951003 REMARK GeneRIF: disorganization of claudin-11 expression in Sertoli cells might be one of ..... Kondo,Y. TITLE Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated ..... Haynes,M.D., Matthews,P.N. and Jiang,W.G. TITLE Claudin-11 decreases the invasiveness of bladder cancer ..... 1503-1509 (2011) PUBMED 21468549 REMARK GeneRIF: claudin-11 may have a role in preventing cancer ..... Lee,J.E., Park,H.J., Park,N.C. and .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 11 (CLDN11), transcript variant 1, mRNA. ..... TITLE Expression pattern of testicular claudin-11 in infertile men JOURNAL Urology 80 (5), 1161 ..... 22951003 REMARK GeneRIF: disorganization of claudin-11 expression in Sertoli cells might be one of ..... Kondo,Y. TITLE Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated ..... Haynes,M.D., Matthews,P.N. and Jiang,W.G. TITLE Claudin-11 decreases the invasiveness of bladder cancer ..... 1503-1509 (2011) PUBMED 21468549 REMARK GeneRIF: claudin-11 may have a role in preventing cancer ..... Lee,J.E., Park,H.J., Park,N.C. and .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 10 (CLDN10), transcript variant a, mRNA. ..... Chen,S.L. and Zeng,L. TITLE Expression of claudin 10 protein in hepatocellular carcinoma: impact on ..... 1213-1218 (2011) PUBMED 21647678 REMARK GeneRIF: Claudin 10 protein is highly expressed in hepatocellular ..... Paakko,P., Harju,T. and Soini,Y. TITLE Claudins 10 and 18 are predominantly expressed in lung ..... 667-673 (2011) PUBMED 22076167 REMARK GeneRIF: Claudin 10/18 are most commonly expressed in lung ..... Female patients and non-smokers express these claudins more commonly suggesting that they may play a ..... Ahn,S.E., Song,Y.S., Song,G. and Han,J.Y. .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 10 (CLDN10), transcript variant b, mRNA. ..... Chen,S.L. and Zeng,L. TITLE Expression of claudin 10 protein in hepatocellular carcinoma: impact on ..... 1213-1218 (2011) PUBMED 21647678 REMARK GeneRIF: Claudin 10 protein is highly expressed in hepatocellular ..... Paakko,P., Harju,T. and Soini,Y. TITLE Claudins 10 and 18 are predominantly expressed in lung ..... 667-673 (2011) PUBMED 22076167 REMARK GeneRIF: Claudin 10/18 are most commonly expressed in lung ..... Female patients and non-smokers express these claudins more commonly suggesting that they may play a ..... Ahn,S.E., Song,Y.S., Song,G. and Han,J.Y. .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 10 (CLDN10), transcript variant a_v1, mRNA. ..... Chen,S.L. and Zeng,L. TITLE Expression of claudin 10 protein in hepatocellular carcinoma: impact on ..... 1213-1218 (2011) PUBMED 21647678 REMARK GeneRIF: Claudin 10 protein is highly expressed in hepatocellular ..... Paakko,P., Harju,T. and Soini,Y. TITLE Claudins 10 and 18 are predominantly expressed in lung ..... 667-673 (2011) PUBMED 22076167 REMARK GeneRIF: Claudin 10/18 are most commonly expressed in lung ..... Female patients and non-smokers express these claudins more commonly suggesting that they may play a ..... Ahn,S.E., Song,Y.S., Song,G. and .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 12 (CLDN12), transcript variant 1, mRNA. ..... 1 to 3684) AUTHORS Ouban,A. and Ahmed,A.A. TITLE Claudins in human cancer: a review JOURNAL Histol. ..... 3684) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Chiba,H. TITLE Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent ..... GeneRIF: These findings strongly suggest that claudin-2- and/or ..... claudin-12-based tight junctions form paracellular Ca(2+) ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 12 (CLDN12), transcript variant 2, mRNA. ..... 1 to 3645) AUTHORS Ouban,A. and Ahmed,A.A. TITLE Claudins in human cancer: a review JOURNAL Histol. ..... 3645) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Chiba,H. TITLE Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent ..... GeneRIF: These findings strongly suggest that claudin-2- and/or ..... claudin-12-based tight junctions form paracellular Ca(2+) ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 12 (CLDN12), transcript variant 3, mRNA. ..... 1 to 3641) AUTHORS Ouban,A. and Ahmed,A.A. TITLE Claudins in human cancer: a review JOURNAL Histol. ..... 3641) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Chiba,H. TITLE Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent ..... GeneRIF: These findings strongly suggest that claudin-2- and/or ..... claudin-12-based tight junctions form paracellular Ca(2+) ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 6 (CLDN6), mRNA. ACCESSION NM_021195 VERSION ..... Biegel,J.A., Pawel,B.R. and Judkins,A.R. TITLE Claudin-6 is a nonspecific marker for malignant rhabdoid ..... kinase 1 is associated with the effect of claudin-6 in breast cancer JOURNAL Diagn Pathol 7, 111 ..... play a positive role in the inhibitory effect of claudin-6 in breast cancer. Publication Status: ..... TITLE The expression patterns and correlations of claudin-6, methy-CpG binding protein 2, DNA ..... 22455563 REMARK GeneRIF: Our results show that claudin-6 protein is significantly down-regulated in ..... Montano,L.F. and Rendon-Huerta,E.P. TITLE .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin domain containing 1 (CLDND1), transcript variant ..... /gene_synonym="C3orf4; GENX-3745" /note="claudin domain containing 1" /db_xref="GeneID:56650" ..... a is encoded by transcript variant 2; claudin domain containing 1 protein; ..... claudin domain-containing protein 1; membrane protein ..... GENX-3745" /codon_start=1 /product="claudin domain-containing protein 1 isoform a" ..... GENX-3745" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin domain containing 1 (CLDND1), transcript variant ..... /gene_synonym="C3orf4; GENX-3745" /note="claudin domain containing 1" /db_xref="GeneID:56650" ..... a is encoded by transcript variant 1; claudin domain containing 1 protein; ..... claudin domain-containing protein 1; membrane protein ..... GENX-3745" /codon_start=1 /product="claudin domain-containing protein 1 isoform a" ..... GENX-3745" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin domain containing 1 (CLDND1), transcript variant ..... /gene_synonym="C3orf4; GENX-3745" /note="claudin domain containing 1" /db_xref="GeneID:56650" ..... b is encoded by transcript variant 4; claudin domain containing 1 protein; ..... claudin domain-containing protein 1; membrane protein ..... GENX-3745" /codon_start=1 /product="claudin domain-containing protein 1 isoform b" ..... GENX-3745" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" exon 219..262 .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin domain containing 1 (CLDND1), transcript variant ..... /gene_synonym="C3orf4; GENX-3745" /note="claudin domain containing 1" /db_xref="GeneID:56650" ..... a is encoded by transcript variant 3; claudin domain containing 1 protein; ..... claudin domain-containing protein 1; membrane protein ..... GENX-3745" /codon_start=1 /product="claudin domain-containing protein 1 isoform a" ..... GENX-3745" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin domain containing 1 (CLDND1), transcript variant ..... /gene_synonym="C3orf4; GENX-3745" /note="claudin domain containing 1" /db_xref="GeneID:56650" ..... a is encoded by transcript variant 6; claudin domain containing 1 protein; ..... claudin domain-containing protein 1; membrane protein ..... GENX-3745" /codon_start=1 /product="claudin domain-containing protein 1 isoform a" ..... GENX-3745" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin domain containing 1 (CLDND1), transcript variant ..... /gene_synonym="C3orf4; GENX-3745" /note="claudin domain containing 1" /db_xref="GeneID:56650" ..... d is encoded by transcript variant 7; claudin domain containing 1 protein; ..... claudin domain-containing protein 1; membrane protein ..... GENX-3745" /codon_start=1 /product="claudin domain-containing protein 1 isoform d" ....." misc_feature <287..628 /gene="CLDND1" /gene_synonym="C3orf4; GENX-3745" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" exon 219..329 .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin domain containing 2 (CLDND2), mRNA. ACCESSION ..... /map="19q13.41" gene 1..990 /gene="CLDND2" /note="claudin domain containing 2" /db_xref="GeneID:125875" ..... 427..930 /gene="CLDND2" /codon_start=1 /product="claudin domain-containing protein 2" .....

..... linear PRI 17-APR-2013 DEFINITION Homo sapiens claudin 18 (CLDN18), transcript variant 2, mRNA. ..... Ishikawa,S., Kokudo,N. and Fukayama,M. TITLE Claudin-18 is an early-stage marker of pancreatic ..... 942-952 (2011) PUBMED 21832145 REMARK GeneRIF: Claudin 18 (a marker for early carcinogenesis) is ..... the protein kinase C pathway might be involved in claudin 18 expression associated with carcinogenesis. ..... Aoki,T., Kokudo,N. and Fukayama,M. TITLE Claudin-18 in biliary neoplasms. Its significance in the ..... and Sawada,N. TITLE Transcriptional regulation of claudin-18 via specific protein kinase C signaling ..... Park,S.W. TITLE Immunohistochemical analysis .....

..... linear PRI 12-MAY-2013 DEFINITION Homo sapiens claudin 16 (CLDN16), mRNA. ACCESSION NM_006580 VERSION ..... and Hasanoglu,A. TITLE A novel mutation of the claudin 16 gene in familial hypomagnesemia with ..... 187-192 (2011) PUBMED 21848011 REMARK GeneRIF: Claudin 16 gene revealed homozygosity for the ..... to 3290) AUTHORS Martin,T.A. and Jiang,W.G. TITLE Claudin-16/paracellin-1, cloning, expression, and its ..... 383-407 (2011) PUBMED 21717372 REMARK GeneRIF: Claudin-16 plays a role beyond that of an initial ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... The protein encoded by this gene, .....

..... linear PRI 15-JUN-2013 DEFINITION Homo sapiens claudin 23 (CLDN23), mRNA. ACCESSION NM_194284 XM_059895 ..... 1972) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... gastric cancer, is a novel member of CLAUDIN gene family JOURNAL Int. J. Mol. Med. 11 (6), ..... Summary: This gene encodes a member of the claudin family. ..... Claudins are integral membrane proteins and components of ..... /gene_synonym="CLDNL; hCG1646163" /note="claudin 23" /db_xref="GeneID:137075" .....

..... linear PRI 16-JUN-2013 DEFINITION Homo sapiens claudin 1 (CLDN1), mRNA. ACCESSION NM_021101 VERSION ..... cell migration and cisplatin sensitivity through claudin1 up-regulation JOURNAL J. Biol. Chem. 288 (16), ..... cell migration and cisplatin sensitivity through claudin1 up-regulation. REFERENCE 3 (bases 1 to 3452) ..... AUTHORS Singh,A.B., Sharma,A. and Dhawan,P. TITLE Claudin-1 expression confers resistance to anoikis in ..... 2538-2547 (2012) PUBMED 22941059 REMARK GeneRIF: Claudin-1 expression confers resistance to anoikis in ..... silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface JOURNAL ..... studies confirm .....

..... linear PRI 16-JUN-2013 DEFINITION Homo sapiens claudin 7 (CLDN7), transcript variant 1, mRNA. ACCESSION ..... and Wang,E.H. TITLE Anti-apoptotic effect of claudin-1 on TNF-alpha-induced apoptosis in human breast ..... 22941467 REMARK GeneRIF: Increased expression of claudin-1 contributes to an anti-apoptotic role in ..... Cicinnati,V.R. and Beckebaum,S. TITLE Claudin-7 expression in hepatocellular carcinoma JOURNAL ..... prognosis among patients with overexpression of claudin-7 in hepatocellular carcinoma. REFERENCE 3 (bases ..... TITLE Prognostic significance of CD24 and claudin-7 immunoexpression in ductal invasive breast ..... 21956537 REMARK GeneRIF: CD24+ .....

..... linear PRI 16-JUN-2013 DEFINITION Homo sapiens claudin 7 (CLDN7), transcript variant 3, mRNA. ACCESSION ..... and Wang,E.H. TITLE Anti-apoptotic effect of claudin-1 on TNF-alpha-induced apoptosis in human breast ..... 22941467 REMARK GeneRIF: Increased expression of claudin-1 contributes to an anti-apoptotic role in ..... Cicinnati,V.R. and Beckebaum,S. TITLE Claudin-7 expression in hepatocellular carcinoma JOURNAL ..... prognosis among patients with overexpression of claudin-7 in hepatocellular carcinoma. REFERENCE 3 (bases ..... TITLE Prognostic significance of CD24 and claudin-7 immunoexpression in ductal invasive breast ..... 21956537 REMARK GeneRIF: CD24+ .....

..... linear PRI 16-JUN-2013 DEFINITION Homo sapiens claudin 7 (CLDN7), transcript variant 2, mRNA. ACCESSION ..... and Wang,E.H. TITLE Anti-apoptotic effect of claudin-1 on TNF-alpha-induced apoptosis in human breast ..... 22941467 REMARK GeneRIF: Increased expression of claudin-1 contributes to an anti-apoptotic role in ..... Cicinnati,V.R. and Beckebaum,S. TITLE Claudin-7 expression in hepatocellular carcinoma JOURNAL ..... prognosis among patients with overexpression of claudin-7 in hepatocellular carcinoma. REFERENCE 3 (bases ..... TITLE Prognostic significance of CD24 and claudin-7 immunoexpression in ductal invasive breast ..... 21956537 REMARK GeneRIF: CD24+ .....

..... linear PRI 16-JUN-2013 DEFINITION Homo sapiens claudin 8 (CLDN8), mRNA. ACCESSION NM_199328 VERSION ..... AUTHORS Shrestha,A. and McClane,B.A. TITLE Human claudin-8 and -14 are receptors capable of conveying the ..... 1 to 2147) AUTHORS Ouban,A. and Ahmed,A.A. TITLE Claudins in human cancer: a review JOURNAL Histol. ..... stain for cytokeratin 7, S100A1 and claudin 8 is valuable in differential diagnosis of ..... GeneRIF: the combination of CK7, S100A1 and claudin 8 immunohistochemistry can be useful for ..... 2147) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... Peterson,P.A. and Yang,Y. TITLE The roles .....

..... linear PRI 24-JUN-2013 DEFINITION Homo sapiens claudin 19 (CLDN19), transcript variant 1, mRNA. ..... and ocular findings: a new claudin-19 mutation JOURNAL Turk. J. Pediatr. 54 (2), ..... hypercalciuria and nephrocalcinosis caused by claudin-19 mutation should be considered. REFERENCE 4 ..... 2859) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... 1 to 2859) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: The product of this gene belongs .....

..... linear PRI 24-JUN-2013 DEFINITION Homo sapiens claudin 19 (CLDN19), transcript variant 2, mRNA. ..... and ocular findings: a new claudin-19 mutation JOURNAL Turk. J. Pediatr. 54 (2), ..... hypercalciuria and nephrocalcinosis caused by claudin-19 mutation should be considered. REFERENCE 4 ..... 3602) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... 1 to 3602) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: The product of this gene belongs .....

..... linear PRI 24-JUN-2013 DEFINITION Homo sapiens claudin 19 (CLDN19), transcript variant 3, mRNA. ..... and ocular findings: a new claudin-19 mutation JOURNAL Turk. J. Pediatr. 54 (2), ..... hypercalciuria and nephrocalcinosis caused by claudin-19 mutation should be considered. REFERENCE 4 ..... 3517) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... 1 to 3517) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: The product of this gene belongs .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 5 (CLDN5), transcript variant 2, mRNA. ACCESSION ..... induces VEGFA-dependent downregulation of claudin 5, which increases the endothelial permeability ..... Tellides,G., Gerke,V. and Pober,J.S. TITLE Claudin-5 controls intercellular barriers of human dermal ..... 489-500 (2013) PUBMED 23288152 REMARK GeneRIF: Claudin-5 expression and junctional organization controls ..... 1720) AUTHORS Hara,H. TITLE Endoglin (CD105) and claudin-5 expression in cutaneous angiosarcoma JOURNAL Am ..... and demonstrate that both endoglin and claudin-5 show promise as markers for cutaneous ..... to microvascular leak: role .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 5 (CLDN5), transcript variant 1, mRNA. ACCESSION ..... induces VEGFA-dependent downregulation of claudin 5, which increases the endothelial permeability ..... Tellides,G., Gerke,V. and Pober,J.S. TITLE Claudin-5 controls intercellular barriers of human dermal ..... 489-500 (2013) PUBMED 23288152 REMARK GeneRIF: Claudin-5 expression and junctional organization controls ..... 2332) AUTHORS Hara,H. TITLE Endoglin (CD105) and claudin-5 expression in cutaneous angiosarcoma JOURNAL Am ..... and demonstrate that both endoglin and claudin-5 show promise as markers for cutaneous ..... to microvascular leak: role .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 15 (CLDN15), transcript variant 2, mRNA. ..... Hoshino,T. and Mizushima,T. TITLE Effect of claudin expression on paracellular permeability, ..... 1384) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... TITLE Differential expression patterns of claudins, tight junction membrane proteins, in mouse ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: This gene encodes a .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 15 (CLDN15), transcript variant 1, mRNA. ..... Hoshino,T. and Mizushima,T. TITLE Effect of claudin expression on paracellular permeability, ..... 2145) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... TITLE Differential expression patterns of claudins, tight junction membrane proteins, in mouse ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: This gene encodes a .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 2 (CLDN2), transcript variant 1, mRNA. ACCESSION ..... permeability and an altered expression of claudin-2 REFERENCE 2 (bases 1 to 2998) AUTHORS Whitcomb ..... reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells JOURNAL Growth ..... autocrine amphiregulin in the upregulation of claudin-2 in Caco-2 epithelial monolayers and consequent ..... Mitic,L.L. and Anderson,J.M. TITLE SUMOylation of claudin-2 JOURNAL Ann. N. Y. Acad. Sci. 1258, 60-64 ..... in MDCK cells resulted in decreased levels of claudin-2 protein by immunoblot and decreased ..... claudin .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 2 (CLDN2), transcript variant 2, mRNA. ACCESSION ..... permeability and an altered expression of claudin-2 REFERENCE 2 (bases 1 to 3163) AUTHORS Whitcomb ..... reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells JOURNAL Growth ..... autocrine amphiregulin in the upregulation of claudin-2 in Caco-2 epithelial monolayers and consequent ..... Mitic,L.L. and Anderson,J.M. TITLE SUMOylation of claudin-2 JOURNAL Ann. N. Y. Acad. Sci. 1258, 60-64 ..... in MDCK cells resulted in decreased levels of claudin-2 protein by immunoblot and decreased ..... claudin .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 2 (CLDN2), transcript variant 3, mRNA. ACCESSION ..... permeability and an altered expression of claudin-2 REFERENCE 2 (bases 1 to 2932) AUTHORS Whitcomb ..... reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells JOURNAL Growth ..... autocrine amphiregulin in the upregulation of claudin-2 in Caco-2 epithelial monolayers and consequent ..... Mitic,L.L. and Anderson,J.M. TITLE SUMOylation of claudin-2 JOURNAL Ann. N. Y. Acad. Sci. 1258, 60-64 ..... in MDCK cells resulted in decreased levels of claudin-2 protein by immunoblot and decreased ..... claudin .....

..... linear PRI 07-JUL-2013 DEFINITION Homo sapiens claudin 24 (CLDN24), mRNA. ACCESSION NM_001185149 ..... 663) AUTHORS Lal-Nag,M. and Morin,P.J. TITLE The claudins JOURNAL Genome Biol. 10 (8), 235 (2009) PUBMED ..... and Blasig,I.E. TITLE Structure and function of claudins JOURNAL Biochim. Biophys. Acta 1778 (3), 631-645 ..... gastric cancer, is a novel member of CLAUDIN gene family JOURNAL Int. J. Mol. Med. 11 (6), ..... 1 to 663) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Summary: This gene encodes .....

..... linear PRI 15-JUL-2013 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant 1, mRNA. ..... AUTHORS Shrestha,A. and McClane,B.A. TITLE Human claudin-8 and -14 are receptors capable of conveying the ..... 1 to 1958) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29 ..... The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a ..... /gene="CLDN14" .....

..... linear PRI 15-JUL-2013 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant 5, mRNA. ..... AUTHORS Shrestha,A. and McClane,B.A. TITLE Human claudin-8 and -14 are receptors capable of conveying the ..... 1 to 1768) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29 ..... The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a ..... /gene="CLDN14" .....

..... linear PRI 15-JUL-2013 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant gamma, mRNA. ..... AUTHORS Shrestha,A. and McClane,B.A. TITLE Human claudin-8 and -14 are receptors capable of conveying the ..... 1 to 1565) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29 ..... The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a ..... /gene="CLDN14" .....

..... linear PRI 15-JUL-2013 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant epsilon, mRNA. ..... AUTHORS Shrestha,A. and McClane,B.A. TITLE Human claudin-8 and -14 are receptors capable of conveying the ..... 1 to 1247) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29 ..... The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a ..... /gene="CLDN14" .....

..... linear PRI 15-JUL-2013 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant 3, mRNA. ..... AUTHORS Shrestha,A. and McClane,B.A. TITLE Human claudin-8 and -14 are receptors capable of conveying the ..... 1 to 1469) AUTHORS Tsukita,S. and Furuse,M. TITLE Claudin-based barrier in simple and stratified cellular ..... Peterson,P.A. and Yang,Y. TITLE The roles of claudin superfamily proteins in paracellular transport ..... Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29 ..... The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a ..... /gene="CLDN14" .....

..... linear PRI 15-JUL-2013 DEFINITION Homo sapiens claudin 4 (CLDN4), mRNA. ACCESSION NM_001305 VERSION ..... 1 to 1846) AUTHORS Ordonez,N.G. TITLE Value of claudin-4 immunostaining in the diagnosis of mesothelioma ..... 611-619 (2013) PUBMED 23596113 REMARK GeneRIF: Claudin-4 is a highly specific and sensitive ..... Wirstlein,P. and Skrzypczak,J. TITLE Aberrant claudin-4 transcript levels in eutopic endometrium of ..... Spillman,M.A. and Baumgartner,H.K. TITLE Claudins play a role in normal and tumor cell motility ..... PUBMED 23521713 REMARK GeneRIF: Knockdown of claudin-4 inhibited cell motility and the mimic peptide ..... had no effect on motility in the .....

..... cell migration and cisplatin sensitivity through claudin1 up-regulation JOURNAL J. Biol. Chem. 288 (16), .....

..... HMSNIA; HNPP; Sp110" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... with high-grade breast carcinomas, basal-like and claudin-low molecular subtypes, and to the breast cancer .....

..... /gene_synonym="CACNLG" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

" sig_peptide 26..85 /gene="TMEM211" /gene_synonym="bA9F11.1" /inference="COORDINATES: ab initio prediction:SignalP:4.0" misc_feature <140..313 /gene="TMEM211" /gene_synonym="bA9F11.1" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" variation .....

..... /gene_synonym="PMP22CD" /note="PMP22 claudin domain containing; PMP22 ..... claudin domain-containing protein" /codon_start=1 ..... /gene_synonym="PMP22CD" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... and Blasig,I.E. TITLE In tight junctions, claudins regulate the interactions between occludin, ..... and marvelD3, which, inversely, modulate claudin oligomerization JOURNAL J. Cell. Sci. 126 (PT 2), .....

..... 202..636 /gene="TMEM202" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" misc_feature .....

..... /gene_synonym="PRO19651" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... transmembrane proteins that are distinct from claudin family members JOURNAL FEBS Lett. 585 (14), ..... 55..591 /gene="TMEM114" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... /gene_synonym="MP17; MP19" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... protein Galphai2: a new partner of claudin-5 that regulates tight junction integrity in ..... 22333621 REMARK GeneRIF: Galphai2 as a novel claudin-5 partner required for TJ integrity in brain .....

" misc_feature <290..565 /gene="TMEM178A" /gene_synonym="TMEM178" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" variation 295 .....

..... 365..841 /gene="TMEM127" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl17758" /db_xref="CDD:248312" misc_feature .....

" sig_peptide 80..148 /gene="TMEM178B" /inference="COORDINATES: ab initio prediction:SignalP:4.0" mat_peptide 149..961 /gene="TMEM178B" /product="Transmembrane protein 178B" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (H3BS89.1)" misc_feature <566..877 /gene="TMEM178B" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:222446" misc_feature .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... transmembrane proteins that are distinct from claudin family members JOURNAL FEBS Lett. 585 (14), ..... /gene_synonym="ARGM1" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" mat_peptide .....

..... transmembrane proteins that are distinct from claudin family members JOURNAL FEBS Lett. 585 (14), ..... /gene_synonym="ARGM1" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" exon 815..952 .....

..... transmembrane proteins that are distinct from claudin family members JOURNAL FEBS Lett. 585 (14), ..... /gene_synonym="ARGM1" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" misc_feature <814..966 /gene="TMEM235" /gene_synonym="ARGM1" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" exon .....

..... cell migration and cisplatin sensitivity through claudin1 up-regulation JOURNAL J. Biol. Chem. 288 (16), .....

..... cell migration and cisplatin sensitivity through claudin1 up-regulation JOURNAL J. Biol. Chem. 288 (16), .....

..... /gene_synonym="C16orf30; CLP24" /note="claudin-like protein 24" /codon_start=1 .....

..... and Blasig,I.E. TITLE In tight junctions, claudins regulate the interactions between occludin, ..... and marvelD3, which, inversely, modulate claudin oligomerization JOURNAL J. Cell. Sci. 126 (PT 2), .....

..... EMP-1; TMP" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... /gene_synonym="XMP" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... /gene_synonym="YMP" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... through differential gene expression analyses: claudin 18 and annexin A8 JOURNAL Am. J. Surg. Pathol. 32 ..... 188-196 (2008) PUBMED 18223320 REMARK GeneRIF: Claudin 18 and annexin A8 are frequently highly .....

..... growth factor (VEGFA)-dependent downregulation of claudin 5, which increases the endothelial permeability .....

..... reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells JOURNAL Growth ..... autocrine amphiregulin in the upregulation of claudin-2 in Caco-2 epithelial monolayers and consequent .....

..... protein Galphai2: a new partner of claudin-5 that regulates tight junction integrity in ..... 22333621 REMARK GeneRIF: Galphai2 as a novel claudin-5 partner required for TJ integrity in brain .....

..... cell migration and cisplatin sensitivity through claudin1 up-regulation JOURNAL J. Biol. Chem. 288 (16), .....

..... cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions JOURNAL J. Biol. ..... localization and degradation of selected claudins. REFERENCE 2 (bases 1 to 1731) AUTHORS .....

..... Escudero-Esparza A, Jiang WG and Martin TA. TITLE Claudin-5 is involved in breast cancer cell motility ..... REMARK GeneRIF: Study portrays a role for Claudin-5 in cell motility involving the N-WASP ..... signalling cascade indicating a possible role for Claudin-5 in the metastasis of human breast cancer. .....

..... silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface JOURNAL ..... studies confirm a role for these CD81 residues in claudin-1 association and Hepatitis C virus infection. .....

..... promotes tumorigenicity by up-regulating claudin-2 expression JOURNAL Proc. Natl. Acad. Sci. ..... PUBMED 20133805 REMARK GeneRIF: Data show that claudin-2 expression was reduced following symplekin ..... down-regulation, and siRNA-mediated claudin-2 down-regulation increased the transepithelial .....

..... /gene_synonym="MRD10" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:216137" misc_feature .....

..... 1218..1790 /gene="CACNG3" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... Schaefer,S.M., Hari,L., Civenni,G., Blunschi,J., Claudinot,S., Okoniewski,M., Beermann,F., .....

..... and Haase,A.T. TITLE A role for syndecan-1 and claudin-2 in microbial translocation during HIV-1 ..... 20700059 REMARK GeneRIF: The authors propose claudin-2 and SYN1 work in concert to enhance microbial .....

..... with high-grade breast carcinomas, basal-like and claudin-low molecular subtypes, and to the breast cancer .....

..... TITLE Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding ..... REMARK GeneRIF: SPCA1 regulates the levels of claudins 1 and 4, but does not affect desmosomal protein .....

..... 64..654 /gene="CACNG4" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" misc_feature .....

..... 388..864 /gene="TMEM127" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl17758" /db_xref="CDD:248312" misc_feature .....

..... /gene_synonym="C16orf30; CLP24" /note="claudin-like protein 24" /codon_start=1 .....

..... /gene_synonym="MP17; MP19" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" variation 176 .....

..... Protein 22 / Epithelial Membrane Proteins and the Claudins JOURNAL BMC Genomics 2, 3 (2001) PUBMED 11472633 ..... protein, related to PMP22/EMPs and the Claudins, localizes to the plasma membrane and the ER. ..... This gene encodes a member of the PMP22/EMP/claudin protein family. The encoded protein is localized ..... TM4SF10" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:222446" misc_feature .....

..... 156..776 /gene="CACNG8" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" misc_feature .....

..... 147..689 /gene="CACNG7" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:222446" misc_feature .....

..... and Blasig,I.E. TITLE In tight junctions, claudins regulate the interactions between occludin, ..... and marvelD3, which, inversely, modulate claudin oligomerization JOURNAL J. Cell. Sci. 126 (PT 2), .....

..... and Haase,A.T. TITLE A role for syndecan-1 and claudin-2 in microbial translocation during HIV-1 ..... 20700059 REMARK GeneRIF: The authors propose claudin-2 and SYN1 work in concert to enhance microbial .....

..... 266..847 /gene="TMEM182" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

" misc_feature <206..406 /gene="GSG1L" /gene_synonym="PRO19651" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" exon 252..363 .....

..... 112..654 /gene="CACNG5" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... USH3AL1" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; cl15797" /db_xref="CDD:210197" misc_feature .....

" sig_peptide 81..155 /gene="TMEM178A" /gene_synonym="TMEM178" /inference="non-experimental evidence, no additional details recorded" /note="Potential; propagated from UniProtKB/Swiss-Prot (Q8NBL3.1)" mat_peptide 156..971 /gene="TMEM178A" /gene_synonym="TMEM178" /product="Transmembrane protein 178A" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (Q8NBL3.1)" misc_feature <585..902 /gene="TMEM178A" /gene_synonym="TMEM178" /note="PMP-22/EMP/MP20/Claudin tight junction; Region: ..... Claudin_2; pfam13903" /db_xref="CDD:206074" misc_feature .....

..... HMSNIA; HNPP; Sp110" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... HMSNIA; HNPP; Sp110" /note="PMP-22/EMP/MP20/Claudin family; Region: ..... PMP22_Claudin; pfam00822" /db_xref="CDD:109862" misc_feature .....

..... cell migration and cisplatin sensitivity through claudin1 up-regulation JOURNAL J. Biol. Chem. 288 (16), .....

..... control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer JOURNAL .....

..... Kondo,Y. TITLE Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated .....

..... cell migration and cisplatin sensitivity through claudin1 up-regulation JOURNAL J. Biol. Chem. 288 (16), .....