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2024-04-19 06:41:49, GGRNA : RefSeq release 60 (20130726)

LOCUS       NR_003225               1973 bp    RNA     linear   PRI 16-JUL-2013
DEFINITION  Homo sapiens lectin, galactoside-binding, soluble, 3 (LGALS3),
            transcript variant 2, non-coding RNA.
ACCESSION   NR_003225 NM_194327
VERSION     NR_003225.2  GI:294345472
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1973)
  AUTHORS   Woodward,A.M., Mauris,J. and Argueso,P.
  TITLE     Binding of transmembrane mucins to galectin-3 limits herpesvirus 1
            infection of human corneal keratinocytes
  JOURNAL   J. Virol. 87 (10), 5841-5847 (2013)
   PUBMED   23487460
  REMARK    GeneRIF: Together, these results indicate that human herpesvirus 1
            exploits galectin-3 to enhance virus attachment to host cells and
            support a protective role for transmembrane by masking viral entry
            mediators on the epithelial glycocalyx.
REFERENCE   2  (bases 1 to 1973)
  AUTHORS   Funasaka,T., Balan,V., Raz,A. and Wong,R.W.
  TITLE     Nucleoporin Nup98 mediates galectin-3 nuclear-cytoplasmic
            trafficking
  JOURNAL   Biochem. Biophys. Res. Commun. 434 (1), 155-161 (2013)
   PUBMED   23541576
  REMARK    GeneRIF: Nup98 RNA interference significantly suppresses downstream
            mRNA expression in the ss-catenin pathway, while nuclear galectin-3
            binds to ss-catenin to inhibit transcriptional activity.
REFERENCE   3  (bases 1 to 1973)
  AUTHORS   Cheng,C.L., Hou,H.A., Lee,M.C., Liu,C.Y., Jhuang,J.Y., Lai,Y.J.,
            Lin,C.W., Chen,H.Y., Liu,F.T., Chou,W.C., Chen,C.Y., Tang,J.L.,
            Yao,M., Huang,S.Y., Ko,B.S., Wu,S.J., Tsay,W. and Tien,H.F.
  TITLE     Higher bone marrow LGALS3 expression is an independent unfavorable
            prognostic factor for overall survival in patients with acute
            myeloid leukemia
  JOURNAL   Blood 121 (16), 3172-3180 (2013)
   PUBMED   23449638
  REMARK    GeneRIF: Higher bone marrow LGALS3 expression is an independent
            poor prognostic factor for overall survival and may serve as a
            potential therapeutic target.
REFERENCE   4  (bases 1 to 1973)
  AUTHORS   Guha,P., Kaptan,E., Bandyopadhyaya,G., Kaczanowska,S., Davila,E.,
            Thompson,K., Martin,S.S., Kalvakolanu,D.V., Vasta,G.R. and Ahmed,H.
  TITLE     Cod glycopeptide with picomolar affinity to galectin-3 suppresses
            T-cell apoptosis and prostate cancer metastasis
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 110 (13), 5052-5057 (2013)
   PUBMED   23479624
  REMARK    GeneRIF: Cod glycopeptide with picomolar affinity to galectin-3
            suppresses T-cell apoptosis and prostate cancer metastasis.
REFERENCE   5  (bases 1 to 1973)
  AUTHORS   Raimond,J., Zimonjic,D.B., Mignon,C., Mattei,M., Popescu,N.C.,
            Monsigny,M. and Legrand,A.
  TITLE     Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at
            region 14q21-22
  JOURNAL   Mamm. Genome 8 (9), 706-707 (1997)
   PUBMED   9271684
REFERENCE   6  (bases 1 to 1973)
  AUTHORS   Rosenberg,I., Cherayil,B.J., Isselbacher,K.J. and Pillai,S.
  TITLE     Mac-2-binding glycoproteins. Putative ligands for a cytosolic
            beta-galactoside lectin
  JOURNAL   J. Biol. Chem. 266 (28), 18731-18736 (1991)
   PUBMED   1917996
REFERENCE   7  (bases 1 to 1973)
  AUTHORS   Raz,A., Carmi,P., Raz,T., Hogan,V., Mohamed,A. and Wolman,S.R.
  TITLE     Molecular cloning and chromosomal mapping of a human
            galactoside-binding protein
  JOURNAL   Cancer Res. 51 (8), 2173-2178 (1991)
   PUBMED   2009535
REFERENCE   8  (bases 1 to 1973)
  AUTHORS   Oda,Y., Leffler,H., Sakakura,Y., Kasai,K. and Barondes,S.H.
  TITLE     Human breast carcinoma cDNA encoding a galactoside-binding lectin
            homologous to mouse Mac-2 antigen
  JOURNAL   Gene 99 (2), 279-283 (1991)
   PUBMED   2022338
REFERENCE   9  (bases 1 to 1973)
  AUTHORS   Gitt,M.A. and Barondes,S.H.
  TITLE     Genomic sequence and organization of two members of a human lectin
            gene family
  JOURNAL   Biochemistry 30 (1), 82-89 (1991)
   PUBMED   1988031
REFERENCE   10 (bases 1 to 1973)
  AUTHORS   Cherayil,B.J., Chaitovitz,S., Wong,C. and Pillai,S.
  TITLE     Molecular cloning of a human macrophage lectin specific for
            galactose
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 87 (18), 7324-7328 (1990)
   PUBMED   2402511
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX641090.1, AL139316.5 and
            BU681070.1.
            On Apr 8, 2010 this sequence version replaced gi:115430224.
            
            Summary: This gene encodes a member of the galectin family of
            carbohydrate binding proteins. Members of this protein family have
            an affinity for beta-galactosides. The encoded protein is
            characterized by an N-terminal proline-rich tandem repeat domain
            and a single C-terminal carbohydrate recognition domain. This
            protein can self-associate through the N-terminal domain allowing
            it to bind to multivalent saccharide ligands. This protein
            localizes to the extracellular matrix, the cytoplasm and the
            nucleus. This protein plays a role in numerous cellular functions
            including apoptosis, innate immunity, cell adhesion and T-cell
            regulation. Alternate splicing results in multiple transcript
            variants.[provided by RefSeq, Apr 2010].
            
            Transcript Variant: This variant (2) has an alternate 5' exon,
            compared to variant 1. This variant is represented as non-coding
            because the use of the 5'-most supported translational start codon,
            as used in variant 1, renders the transcript a candidate for
            nonsense-mediated mRNA decay (NMD).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               BX641090.1         4-173
            171-172             AL139316.5         89212-89213         c
            173-1234            BX641090.1         174-1235
            1235-1336           AL139316.5         88048-88149         c
            1337-1436           BX641090.1         1338-1437
            1437-1437           AL139316.5         86041-86041         c
            1438-1825           BX641090.1         1439-1826
            1826-1973           BU681070.1         1-148               c
FEATURES             Location/Qualifiers
     source          1..1973
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q22.3"
     gene            1..1973
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /note="lectin, galactoside-binding, soluble, 3"
                     /db_xref="GeneID:3958"
                     /db_xref="HGNC:6563"
                     /db_xref="MIM:153619"
     misc_RNA        1..1973
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /product="lectin, galactoside-binding, soluble, 3,
                     transcript variant 2"
                     /db_xref="GeneID:3958"
                     /db_xref="HGNC:6563"
                     /db_xref="MIM:153619"
     exon            1..1386
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /inference="alignment:Splign:1.39.8"
     variation       94
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:79834356"
     variation       95
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:77139802"
     variation       125
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137979468"
     variation       127
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201060113"
     variation       174
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77419946"
     variation       202
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149471573"
     variation       291
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:45509294"
     variation       311
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181801745"
     variation       320
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61975413"
     misc_feature    392..685
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /inference="COORDINATES:
                     alignment:Blast2seq::RefSeq|NM_002306.3"
                     /note="primary ORF has stop codon >50 nucleotides from the
                     terminal splice site; nonsense-mediated decay (NMD)
                     candidate"
     variation       409
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78001930"
     variation       416
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115891972"
     variation       424
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376924677"
     variation       446
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199699629"
     variation       452
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368909393"
     variation       485
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116659993"
     variation       523
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114186444"
     variation       537
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:36059179"
     variation       540
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:74050920"
     variation       584
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373732487"
     variation       608
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:28415601"
     variation       653
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2075598"
     variation       672
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375560337"
     variation       702
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186115963"
     variation       754
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:78054476"
     variation       856
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377064913"
     variation       1011..1013
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace=""
                     /replace="ctg"
                     /db_xref="dbSNP:10606761"
     variation       1013..1015
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace=""
                     /replace="gct"
                     /db_xref="dbSNP:60179062"
     variation       1013
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201605915"
     variation       1056
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:377694711"
     variation       1062
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370981249"
     variation       1068
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188973411"
     variation       1073
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202159462"
     variation       1074
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11538648"
     variation       1116
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181337247"
     variation       1117
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367771588"
     variation       1156
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:199980622"
     variation       1181
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200440596"
     variation       1182
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375563484"
     variation       1183
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201423229"
     variation       1202
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201924703"
     variation       1204
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11538647"
     variation       1228
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374075223"
     variation       1234
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375132388"
     variation       1235
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:4644"
     variation       1244
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372168966"
     variation       1257
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61735588"
     variation       1298
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201462121"
     variation       1324
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148184206"
     variation       1336
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:4652"
     variation       1338
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:78964872"
     variation       1346
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200922957"
     variation       1353
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372459819"
     variation       1356
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377311837"
     variation       1384
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369880363"
     exon            1387..1475
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /inference="alignment:Splign:1.39.8"
     variation       1430
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201398647"
     variation       1438
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370418608"
     variation       1475
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374133862"
     exon            1476..1641
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /inference="alignment:Splign:1.39.8"
     variation       1482
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371871619"
     variation       1492
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:199729394"
     variation       1503
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184778469"
     variation       1506
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145296140"
     variation       1528
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376506811"
     variation       1529
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201865041"
     variation       1542
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201301078"
     variation       1545
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137885280"
     variation       1555
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189412756"
     variation       1592
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10148371"
     variation       1607
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200686001"
     variation       1616
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373019488"
     exon            1642..1956
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /inference="alignment:Splign:1.39.8"
     variation       1642
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201096256"
     variation       1647
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:11125"
     variation       1702
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11001"
     variation       1728
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374550386"
     variation       1754
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1042869"
     variation       1763
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150161752"
     variation       1783
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138668217"
     variation       1799
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1042896"
     variation       1813
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:61975414"
     variation       1815
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:74959172"
     variation       1816
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:71659941"
     variation       1818..1819
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace=""
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:71736436"
     variation       1832
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1042906"
     variation       1847
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371349669"
     variation       1864
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1042918"
     variation       1876
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369980295"
     variation       1894
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182580267"
     variation       1949..1950
                     /gene="LGALS3"
                     /gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
                     MAC2"
                     /replace=""
                     /replace="at"
                     /db_xref="dbSNP:149894805"
ORIGIN      


gtgtgcaaatagaggaataaatagcagggcagcaactatgtctggaggtcattgtctttcctgtctcagtagtaatcaatcactgcttatcttcaaaaacccagagtaggggatggggcagttagtggggacagagggcagatgggtaagattcagagcacaggctagtgtgacggaagtttaaacttgtgagttaaatagggtttggcaatctagctggatagcatccctgccccttgaagagatgtttttgtggcgccacactactgacttaggcataatgcctagagatggattagaactgcacaatgaactagtggtgaggttcagtttaatggaaattggtgaaagcttttaggataaaatgataatctttgtttctttcaggaaaatggcagacaatttttcggtaagtgttttatgcctgtttcttccccttgatcagctccacatggttgagggttgggggttttgtttttaccatgactttcccttttcactctcccactgcgtggcttcccctggactcatttgtccaatgagggcttgcaagctggagccttgtttttccagcagcagatttgggaagaaagccaggcagagcgaggcctgggactcactcacagtaaccctttcaccaaaaggcccagggcggaagggagtggactctgccggcaggagctgagaaatcctctgagtagcgggaagtgcggtacagtctgggcattctgatgtttgtgattgtttttctcacggtgatgaaaaagtatgtgctataagtagaggagcgctaactcctgacttgagctaattatgaaaatgcagccctccctgatctgagacgttgggaggcaagaataaagtgaaaaagtatatgtaatcccaacatctaattttagtcttagaaactcaaactattaataagtggaaaaagtttaatgatatgcatgtaatgcctttgccatattcctctccttcttagatcacatattcctattttcctgaaaattctgcttttgagaatgctttctgtcccgtaattgtgtatgtctttctttccagctccatgatgcgttatctgggtctggaaacccaaaccctcaaggatggcctggcgcatgggggaaccagcctgctggggcagggggctacccaggggcttcctatcctggggcctaccccgggcaggcacccccaggggcttatcctggacaggcacctccaggcgcctaccctggagcacctggagcttatcccggagcacctgcacctggagtctacccagggccacccagcggccctggggcctacccatcttctggacagccaagtgccaccggagcctaccctgccactggcccctatggcgcccctgctgggccactgattgtgccttataacctgcctttgcctgggggagtggtgcctcgcatgctgataacaattctgggcacggtgaagcccaatgcaaacagaattgctttagatttccaaagagggaatgatgttgccttccactttaacccacgcttcaatgagaacaacaggagagtcattgtttgcaatacaaagctggataataactggggaagggaagaaagacagtcggttttcccatttgaaagtgggaaaccattcaaaatacaagtactggttgaacctgaccacttcaaggttgcagtgaatgatgctcacttgttgcagtacaatcatcgggttaaaaaactcaatgaaatcagcaaactgggaatttctggtgacatagacctcaccagtgcttcatataccatgatataatctgaaaggggcagattaaaaaaaaaaaaagaatctaaaccttacatgtgtaaaggtttcatgttcactgtgagtgaaaatttttacattcatcaatatccctcttgtaagtcatctacttaataaatattacagtgaattacctgtctcaatatgtcaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:3958 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:3958 -> Molecular function: GO:0019863 [IgE binding] evidence: IEA
            GeneID:3958 -> Molecular function: GO:0030246 [carbohydrate binding] evidence: IEA
            GeneID:3958 -> Biological process: GO:0001501 [skeletal system development] evidence: IEA
            GeneID:3958 -> Biological process: GO:0006397 [mRNA processing] evidence: IEA
            GeneID:3958 -> Biological process: GO:0008380 [RNA splicing] evidence: IEA
            GeneID:3958 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
            GeneID:3958 -> Biological process: GO:0030198 [extracellular matrix organization] evidence: IEA
            GeneID:3958 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:3958 -> Cellular component: GO:0005578 [proteinaceous extracellular matrix] evidence: IEA
            GeneID:3958 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:3958 -> Cellular component: GO:0005681 [spliceosomal complex] evidence: IEA
            GeneID:3958 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:3958 -> Cellular component: GO:0005743 [mitochondrial inner membrane] evidence: IDA
            GeneID:3958 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
            GeneID:3958 -> Cellular component: GO:0031012 [extracellular matrix] evidence: IDA

by @meso_cacase at DBCLS
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