GGRNA | NM_144675.2

LOCUS       NM_144675               4538 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens GSG1-like (GSG1L), transcript variant 2, mRNA.
ACCESSION   NM_144675
VERSION     NM_144675.2  GI:157951719
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4538)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS ONE 7 (12), E51954 (2012)
   PUBMED   23251661
REFERENCE   2  (bases 1 to 4538)
  AUTHORS   Rual,J.F., Hirozane-Kishikawa,T., Hao,T., Bertin,N., Li,S.,
            Dricot,A., Li,N., Rosenberg,J., Lamesch,P., Vidalain,P.O.,
            Clingingsmith,T.R., Hartley,J.L., Esposito,D., Cheo,D., Moore,T.,
            Simmons,B., Sequerra,R., Bosak,S., Doucette-Stamm,L., Le Peuch,C.,
            Vandenhaute,J., Cusick,M.E., Albala,J.S., Hill,D.E. and Vidal,M.
  TITLE     Human ORFeome version 1.1: a platform for reverse proteomics
  JOURNAL   Genome Res. 14 (10B), 2128-2135 (2004)
   PUBMED   15489335
REFERENCE   3  (bases 1 to 4538)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res. 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC016460.1, AC008732.9 and DB306756.1.
            On Oct 6, 2007 this sequence version replaced gi:21389570.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016460.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025088 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1172              BC016460.1         1-1172
            1173-4414           AC008732.9         167078-170319
            4415-4538           DB306756.1         1-124               c
FEATURES             Location/Qualifiers
     source          1..4538
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p12.1"
     gene            1..4538
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /note="GSG1-like"
                     /db_xref="GeneID:146395"
                     /db_xref="HGNC:28283"
                     /db_xref="HPRD:14464"
     exon            1..98
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    77..79
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /note="upstream in-frame stop codon"
     exon            99..251
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /inference="alignment:Splign:1.39.8"
     CDS             167..697
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /note="isoform 2 is encoded by transcript variant 2; germ
                     cell-specific gene 1-like protein; KTSR5831; GSG1-like
                     protein"
                     /codon_start=1
                     /product="germ cell-specific gene 1-like protein isoform
                     2"
                     /protein_id="NP_653276.1"
                     /db_xref="GI:21389571"
                     /db_xref="CCDS:CCDS10631.1"
                     /db_xref="GeneID:146395"
                     /db_xref="HGNC:28283"
                     /db_xref="HPRD:14464"
                     /translation="

MCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPEAIKYFRERMEKRDGSEEDFHLDCRHERYPARHQPHMADSWPRSSAQEAPELNRQCWVLGHWV

"
     misc_feature    <206..406
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl15797"
                     /db_xref="CDD:210197"
     exon            252..363
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /inference="alignment:Splign:1.39.8"
     exon            364..531
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /inference="alignment:Splign:1.39.8"
     exon            532..599
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /inference="alignment:Splign:1.39.8"
     exon            600..4538
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /inference="alignment:Splign:1.39.8"
     STS             905..1052
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /standard_name="RH91752"
                     /db_xref="UniSTS:87375"
     STS             1024..1166
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /standard_name="D16S2573E"
                     /db_xref="UniSTS:151654"
     variation       1051
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2292646"
     variation       1078
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2292647"
     STS             3394..3665
                     /gene="GSG1L"
                     /gene_synonym="PRO19651"
                     /standard_name="SHGC-147786"
                     /db_xref="UniSTS:176011"
ORIGIN

ggcagctgagtcagtgagcagcgccatgatgaggggcagtccctgccagcaccaacaggggctggaaacccagcgataggagcatcagcatctccgaggggtcctgtggctgtctgtggtctccgaggtgctgtacattctgctgctggtggttggcttcagcctcatgtgtctcgagctcttccactccagcaatgtcatcgacgggctcaagctcaatgccttcgcggctgtcttcacggtgctctcaggcctcctgggaatggtcgcccacatgatgtacacgcaggtgttccaggtcaccgtgagcctcggtcctgaggactggagaccccattcctgggactacgggtggtccttctgcctggcgtggggctcctttacctgctgcatggcagcctctgtcaccacgctcaactcctacaccaagacggtcattgagttccggcacaagcgcaaggtctttgagcagggctaccgggaagagccgaccttcatagaccctgaggccatcaagtacttccgggagaggatggagaagagggacgggagcgaggaggactttcacttagactgccgccacgagagataccctgcccgacaccagccacacatggcggattcctggccccggagctccgcacaggaagcaccagagctgaaccgacagtgctgggtcttggggcactgggtgtgaccaagacctcaacctggcccgcggacctcaggccatcgctggcaccagcccctgctgcaagaccaccagagtggtgcccccagaaccctggcctgtgtgccgtgaactcagtcagcctgcgtgggagatgccaggcctgtcctgcccatcgctgcctgggtcccatggccttggaaatggggccagggcaggcccaagggaatgcacagggctgcacagagtgactttgggacagcagccccggactcttgccatcatcacatgagccctgctgggcacagctgcgatgccaggagacacatggccactggccactgaatggctggcacccacaagccagtcaggtgcccagaggggcagagccctttggggggcagagagtggcttcctgaaggagggggcagtggcgcaggcactgcaggggtgtcacacagcaggcacacagcaggggctcaataaatgcttgttgaacttgttttcttgcggtgtatggaggccagttgctctgtgggctgtggctgccctgtcattgccccaccccattactcctcaaggaggctgaaggtgacagcagagactgtgcagaggccagggccagacactgcagggtggcagggagggagcacagagcccaggctggacacaggctggcagggctgccttgtattccagagagtgggcaaggcaggggccaggcaagcaagagatgtggggcgagcaagaagtgggcccccaaacccaagccctaagcagggagggtgaagaagccacatttctcttcagagctcagcaacatcacaccaccctgaccctgaggaggctttaccctgtgcctagcaccacctttacagaaaatcccagggcttagatgcctggagaaacagattcttattataaagaggaggaaaattagggtcacagagatgaatgaagtaacttgcctgtgattacagagctagcaaatggcagagatggggtttgaatcaggactcctgactccaagttcagtcatttcccaagaggccttattccttcccagaagaatttctagagcttttccccacgtagaatatattcttctcctttatccttccatccttccatccatcatccatcactcatccagccattatccattatccatccatccattcatcattcgtccatctattatccacccattcatcatctattatccatccatcattcatcatccatccatcattcataattcatctttccactcatccatccatcattcattcattcatccatccttccatccatccatcatctatccattcatccatccatttgccatccatccactcattcatcagctatccatcatctatccatccatccatccatccagcatctatcactcatccagctattgtccattgtccattcatccatttttcattcatccctccatcatcattaatccattatccacccactcatcatctattatccatctatagtccatcaaccatccatccttcatcatccatccatccatccttcatccatccatccacccatccatccatccatcatctgtccatccattatctatccattcatccatccattcatcatccacccacctattcatcagctatctatccatcatccatccatccatcatccatccatccatccatccatccatcatctatccattcattgtctatgctttcatccatccattcatcatccatccacccattcgttagctatttatccattatccattcctccatctatccatcatccattcatcccttatccattcaaccattatgcatttcttcatttatccattatttatccttccatccatcatccatcatctttccatccactatctatccattcatccatctatccatcatccatccatcctttatccatcattcatcagccatcatccctccatctatccattatccatcatccactcatccattcatccctccatctgcccattatccatcaaccatccatccatccattatccgtcatccacacatccattcatccctccatctgcccattatccatcaaccatccatccatccattatccatttctgcattatccatttattctttatccatttcttcatctattcatcatctatccatccattatccttacacctatctatcatccatccattccttcatctatccatcatccatcaattatccatccattcatccatccatctatccatcttctattgattgcttgtcatccttccttgtatcagacttccatccatcctccttccatgtgtcacacatcctcattactcaaccatccagctgtgcatccatctattcactgatatagttcactgtgcccctactatgtgccaagcactgtggtaggcacttgaggtgggatgctggagcatccagagagggcatctattgtcgtgagcctgggttcagattccaccttctccacttgtgaccttgggcgagttacttgacctttctgtgcctgtttcctcatccattaaatccggataatcattatacctacctcttcaagctgttgtgcaaattaaatgagctaacatatttgaagtgtctagaacagagcctggcacaagtaaacactttgtgggtgtttactaacaggacaacaaggggaaatcggggctgtgggagctgtagtctagggaggctcctttgagaaaatgatgtctaagccaagacatgaagattgtctgggcatcagccaggcaagagtatagcagggaaagaaagtacattagaggactttaaaatagtcccaatggcaggtgtggagagcagggaggtcaggaggcagttgtgggaaattaggcatcagagggcagtggagccaggccaggaggaactggaaaccttcttagggagcttagagtttaccctggggcaatggggagtgggcagtgagatgcttttagcagactgggatgcgcctgggtgtacatttgaggaagatcaccgcaactatgggcacagaatagttgtgggagatgcttctcccttcctcatccctcttacactcaagaaagagaagaaagtgggctggcttaggaaagttgccctggggaggggaccatgcgggcagattcaggaaccaattaggagggaatagactgagtgggagaagaggaaagttggtgacgactctcaggttacagggtcagcttgggggatagggaagacggagacttcgtggttcagatgtcttgagtctcaggggctcaggggacagccagctggaggtttgtgctcattcattcacgcattgattcatcaagcgaacaatttgttaattcactttccattcattcagtaaatattaatgacctactaggtggggcttaaggcggggctggaaatgggcctgggagagcaattatggtccagctctactgaggccttgaatgtcagaacaaggaatttgggctttggcctcatgcaagagagggcggctgccatatatgggcctgggcagggacagatctgacagggatctagccctggccaccaggcatctaggagctcttgttctcacccagggtccttctgaagttggcgagtggaccgcaggaggtccaggagatgattgtagttgacacatggggaaaattttaatctattttaatagttgtgtttatgtaaatgtgtattagaaaaaaatgtacagtgggcacatcagtgctatgacttcacagacgttactgcttaggatgaaaccaaaataggcatttaagtaaaagaaaaaaagagttggcttaaagaaaaatattaaataaataatcgtgcaagtg

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