LOCUS       NM_017629               7069 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens argonaute RISC catalytic component 4 (AGO4), mRNA.
ACCESSION   NM_017629
VERSION     NM_017629.3  GI:324073532
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7069)
  AUTHORS   Li,L., Yu,C., Gao,H. and Li,Y.
  TITLE     Argonaute proteins: potential biomarkers for human colon cancer
  JOURNAL   BMC Cancer 10, 38 (2010)
   PUBMED   20146808
  REMARK    GeneRIF: EIF2C2-4 and PIWIL4 appear increased in advanced tumors
            with distant metastasis, suggesting they may promote tumor invasion
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7069)
  AUTHORS   Potenza,N., Papa,U. and Russo,A.
  TITLE     Differential expression of Dicer and Argonaute genes during the
            differentiation of human neuroblastoma cells
  JOURNAL   Cell Biol. Int. 33 (7), 734-738 (2009)
   PUBMED   19393748
  REMARK    GeneRIF: EIF2C4 protein is expressed in differentiating and
            terminally differentiated N-type cells more than in S- and I-type
            cells
REFERENCE   3  (bases 1 to 7069)
  AUTHORS   Lazzaretti,D., Tournier,I. and Izaurralde,E.
  TITLE     The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence
            bound transcripts independently of Argonaute proteins
  JOURNAL   RNA 15 (6), 1059-1066 (2009)
   PUBMED   19383768
REFERENCE   4  (bases 1 to 7069)
  AUTHORS   Weinmann,L., Hock,J., Ivacevic,T., Ohrt,T., Mutze,J., Schwille,P.,
            Kremmer,E., Benes,V., Urlaub,H. and Meister,G.
  TITLE     Importin 8 is a gene silencing factor that targets argonaute
            proteins to distinct mRNAs
  JOURNAL   Cell 136 (3), 496-507 (2009)
   PUBMED   19167051
REFERENCE   5  (bases 1 to 7069)
  AUTHORS   Wu,L., Fan,J. and Belasco,J.G.
  TITLE     Importance of translation and nonnucleolytic ago proteins for
            on-target RNA interference
  JOURNAL   Curr. Biol. 18 (17), 1327-1332 (2008)
   PUBMED   18771919
  REMARK    GeneRIF: The specificity of RNA interference depends on the
            concentration of Ago1, Ago3, and Ago4 relative to Ago2.
REFERENCE   6  (bases 1 to 7069)
  AUTHORS   Tao,W.A., Wollscheid,B., O'Brien,R., Eng,J.K., Li,X.J.,
            Bodenmiller,B., Watts,J.D., Hood,L. and Aebersold,R.
  TITLE     Quantitative phosphoproteome analysis using a dendrimer conjugation
            chemistry and tandem mass spectrometry
  JOURNAL   Nat. Methods 2 (8), 591-598 (2005)
   PUBMED   16094384
REFERENCE   7  (bases 1 to 7069)
  AUTHORS   Sasaki,T., Shiohama,A., Minoshima,S. and Shimizu,N.
  TITLE     Identification of eight members of the Argonaute family in the
            human genome small star, filled
  JOURNAL   Genomics 82 (3), 323-330 (2003)
   PUBMED   12906857
REFERENCE   8  (bases 1 to 7069)
  AUTHORS   Doi,N., Zenno,S., Ueda,R., Ohki-Hamazaki,H., Ui-Tei,K. and Saigo,K.
  TITLE     Short-interfering-RNA-mediated gene silencing in mammalian cells
            requires Dicer and eIF2C translation initiation factors
  JOURNAL   Curr. Biol. 13 (1), 41-46 (2003)
   PUBMED   12526743
REFERENCE   9  (bases 1 to 7069)
  AUTHORS   Carmell,M.A., Xuan,Z., Zhang,M.Q. and Hannon,G.J.
  TITLE     The Argonaute family: tentacles that reach into RNAi, developmental
            control, stem cell maintenance, and tumorigenesis
  JOURNAL   Genes Dev. 16 (21), 2733-2742 (2002)
   PUBMED   12414724
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AB046787.1, AL359186.15 and
            CA419947.1.
            On Feb 25, 2011 this sequence version replaced gi:29029592.
            
            Summary: This gene encodes a member of the Argonaute family of
            proteins which play a role in RNA interference. The encoded protein
            is highly basic containing PAZ and PIWI domains, and it may play a
            role in short-interfering-RNA-mediated gene silencing. This gene is
            located on chromosome 1 in a cluster of closely related family
            members including argonaute 3, and eukaryotic translation
            initiation factor 2C, 1. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC152450.1, AB046787.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025083, ERS025084 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5990              AB046787.1         1-5990
            5991-6846           AL359186.15        44571-45426
            6847-7069           CA419947.1         1-223               c
FEATURES             Location/Qualifiers
     source          1..7069
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34"
     gene            1..7069
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="argonaute RISC catalytic component 4"
                     /db_xref="GeneID:192670"
                     /db_xref="HGNC:18424"
                     /db_xref="HPRD:09559"
                     /db_xref="MIM:607356"
     exon            1..209
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       12
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374107467"
     variation       50
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181835216"
     CDS             191..2776
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="argonaute 4; eukaryotic translation initiation
                     factor 2C, 4; hAgo4; eIF2C 4; eIF-2C 4; argonaute4"
                     /codon_start=1
                     /product="protein argonaute-4"
                     /protein_id="NP_060099.2"
                     /db_xref="GI:29029593"
                     /db_xref="CCDS:CCDS397.1"
                     /db_xref="GeneID:192670"
                     /db_xref="HGNC:18424"
                     /db_xref="HPRD:09559"
                     /db_xref="MIM:607356"
                     /translation="

MEALGPGPPASLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA

"
     misc_feature    233..2770
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="protein argonaute; Provisional; Region: PLN03202"
                     /db_xref="CDD:178743"
     misc_feature    683..841
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="Domain of unknown function (DUF1785); Region:
                     DUF1785; pfam08699"
                     /db_xref="CDD:204029"
     misc_feature    839..1201
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:30331"
     misc_feature    order(995..997,1040..1042,1082..1084,1094..1096,
                     1148..1150,1169..1171,1175..1177)
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:30331"
     misc_feature    1340..2647
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="Piwi_ago-like: PIWI domain, Argonaute-like
                     subfamily. Argonaute is the central component of the
                     RNA-induced silencing complex (RISC) and related
                     complexes. The PIWI domain is the C-terminal portion of
                     Argonaute and consists of two subdomains, one of...;
                     Region: Piwi_ago-like; cd04657"
                     /db_xref="CDD:72942"
     misc_feature    order(1751..1753,1763..1765,1799..1810,1817..1819,
                     1841..1843,1850..1852,1862..1864,1874..1876)
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="5' RNA guide strand anchoring site; other site"
                     /db_xref="CDD:72942"
     misc_feature    order(1955..1957,1961..1963,2201..2203,2615..2617)
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /note="active site"
                     /db_xref="CDD:72942"
     misc_feature    2582..2584
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
                     /citation=[6]
     variation       200
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111333297"
     exon            210..375
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       239
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140000177"
     variation       251
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369399832"
     variation       278
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376727706"
     variation       297
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:183963488"
     variation       368
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368029178"
     exon            376..496
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       428
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376006576"
     variation       429
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368810209"
     exon            497..678
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       504
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370390132"
     variation       511
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184987317"
     variation       523
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372941854"
     variation       563
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377325462"
     variation       604
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370951796"
     variation       670..671
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35921249"
     variation       672
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144740654"
     exon            679..815
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       684
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141882799"
     variation       685
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368683042"
     variation       688
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143995149"
     variation       695
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370159437"
     variation       716..717
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:35950874"
     variation       716
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374925290"
     variation       788
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200471384"
     variation       795
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201828878"
     exon            816..950
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       860
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376648938"
     variation       862
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147992114"
     variation       886
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148256871"
     exon            951..1038
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     exon            1039..1186
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       1067
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376527323"
     variation       1070
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369653734"
     variation       1101
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200766835"
     variation       1130
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373177705"
     exon            1187..1306
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       1231
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200016040"
     variation       1301
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371188863"
     variation       1303
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376270425"
     exon            1307..1435
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       1322
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150537720"
     variation       1334
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374546913"
     variation       1358
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202106464"
     variation       1417
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200535337"
     exon            1436..1569
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       1458
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368090587"
     variation       1489
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149619232"
     variation       1523
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201957022"
     exon            1570..1754
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       1616
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149862215"
     variation       1701
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:140901871"
     variation       1713
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372203799"
     exon            1755..1914
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       1793
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375566918"
     variation       1846
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112398949"
     exon            1915..2230
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       2028
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200451864"
     variation       2050
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142753498"
     variation       2054
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201183539"
     variation       2059
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376006355"
     variation       2069
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369348803"
     variation       2071
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373422169"
     variation       2128
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199855288"
     variation       2168
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140974452"
     variation       2169
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146736735"
     variation       2193
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377632953"
     exon            2231..2365
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       2258
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200474840"
     variation       2281
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373750542"
     variation       2286
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:145609935"
     variation       2292
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377052492"
     variation       2308
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146550322"
     variation       2337
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200351585"
     variation       2351
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370463826"
     variation       2353
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374955692"
     exon            2366..2467
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       2409
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142769387"
     variation       2455
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:139289038"
     exon            2468..2667
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       2542
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150907205"
     variation       2584
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:4652895"
     variation       2594
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148713478"
     variation       2665
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368697141"
     exon            2668..7061
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /inference="alignment:Splign:1.39.8"
     variation       2670
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189230027"
     variation       2679
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372745703"
     variation       2718
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201449888"
     variation       2745
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374855000"
     variation       2791
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369254382"
     variation       2825
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371692112"
     variation       2992
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181092178"
     variation       3131..3133
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="aga"
                     /db_xref="dbSNP:370578139"
     variation       3250
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143513803"
     variation       3252
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:34406706"
     variation       3512
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185475220"
     variation       3518
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188774332"
     variation       3543..3544
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:200764891"
     variation       3544
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:149653098"
     variation       3587
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:12068665"
     variation       3655
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:72902959"
     variation       3715
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142922183"
     variation       3728
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145121227"
     variation       3742
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:181662005"
     variation       3763
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370121658"
     variation       3814
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:35830885"
     variation       3940
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186180533"
     variation       4075
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192454199"
     polyA_signal    4076..4081
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
     polyA_site      4099
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
     variation       4136
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:138991047"
     variation       4225
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373322053"
     variation       4374
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41267261"
     variation       4471
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:12059301"
     variation       4502
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150822052"
     variation       4512
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139277923"
     variation       4527
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75380846"
     variation       4546
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:183954294"
     variation       4550
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372613235"
     variation       4637
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:77235743"
     variation       4684
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375907047"
     variation       4718
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11803314"
     variation       4824
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:67520708"
     variation       4865
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368851852"
     variation       4867
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185979298"
     variation       4886
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11263829"
     variation       4891
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:144303118"
     variation       5058
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111482723"
     variation       5136
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148747333"
     variation       5150
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:74653221"
     variation       5193
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:74607403"
     variation       5304
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145204399"
     variation       5326
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369712764"
     variation       5372
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78403130"
     variation       5413
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375152095"
     variation       5490
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190797025"
     variation       5541
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200436813"
     variation       5560
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370147334"
     variation       5601
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:147615092"
     variation       5629
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:182530337"
     variation       5723
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187324612"
     STS             5809..5928
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /standard_name="D11S2560"
                     /db_xref="UniSTS:37928"
     variation       6000..6002
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="aag"
                     /db_xref="dbSNP:76637434"
     variation       6002..6003
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="gg"
                     /db_xref="dbSNP:149478166"
     variation       6002
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12562615"
     variation       6002
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="gg"
                     /db_xref="dbSNP:5773513"
     variation       6013
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76361293"
     variation       6051
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114543266"
     variation       6065
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375108953"
     variation       6077
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192148278"
     variation       6107..6108
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="act"
                     /db_xref="dbSNP:200177278"
     variation       6108..6109
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace=""
                     /replace="cta"
                     /db_xref="dbSNP:367727843"
     variation       6110
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113774917"
     variation       6332
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113583821"
     variation       6350
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374057841"
     variation       6555
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77661035"
     STS             6846..6978
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /standard_name="A009K46"
                     /db_xref="UniSTS:29384"
     STS             6846..6978
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /standard_name="G32631"
                     /db_xref="UniSTS:117214"
     variation       6898
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144568712"
     STS             6900..7002
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /standard_name="SHGC-74548"
                     /db_xref="UniSTS:12802"
     variation       7010
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183131271"
     polyA_signal    7040..7045
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
     polyA_site      7061
                     /gene="AGO4"
                     /gene_synonym="EIF2C4"
ORIGIN      

gagccggagccgggtccctgtccccgggccgggcgccgccgccgccccctgcccagcgcccgcgtctccgcggcgccaccccagcgccaatattccggagatcaagcgttacgcggcggcggcggcggcggcggcggggcccggagcgggaggcgccggggaccggggcgaggcggcccccgccgccgccatggaggcgctgggacccggacctccggctagcctgtttcagccacctcgtcgtcctggccttggaactgttggaaaaccaattcgactgttagccaatcattttcaggttcagattcctaaaatagatgtgtatcactatgatgtggatattaagcctgaaaaacggcctcgtagagtcaacagggaggtagtagatacaatggtgcggcacttcaagatgcaaatatttggtgatcggcagcctgggtatgatggcaaaagaaacatgtacacagcacatccactaccaattggacgggatagggttgatatggaggtgactcttccaggcgagggtaaagaccaaacatttaaagtgtctgttcagtgggtgtcagttgtgagccttcagttgcttttagaagctttggctgggcacttgaatgaagtcccagatgactcagtacaagcacttgatgttatcacaagacaccttccctccatgaggtacaccccagtgggccgttcctttttctcacccccggaaggttactaccaccctctgggagggggcagggaggtctggtttggttttcatcagtctgtgagacctgccatgtggaatatgatgctcaacattgatgtatctgcaactgctttctaccgggctcagcctatcattgagttcatgtgtgaggttttagacattcagaacatcaatgaacagaccaaacctctaacagactcccagcgtgtcaaatttaccaaagaaatcagaggtctcaaagttgaggtgacccactgtggacagatgaaacgaaaataccgagtttgtaatgtgactagacggccagccagtcatcaaacttttcctttgcagctagaaaacggtcaagctatggaatgtacagtagctcaatattttaagcaaaagtatagtctgcaactgaaatacccccatcttccctgtctccaagtgggacaagaacaaaagcatacatacttgccactcgaggtctgtaatatagtggcaggacagcgatgtatcaagaagctcacagacaatcagacttccacaatgatcaaagctacagcaagatctgctcctgacagacaggaagagatcagtagactggtgaagagcaacagtatggtgggtggacctgatccataccttaaagaatttggtattgttgtccacaatgaaatgacagagctcacaggcagggtacttccagcaccaatgctgcaatatggaggccggaataaaacagtagccacacccaaccagggtgtctgggacatgcgaggaaagcagttttatgctggcattgaaattaaagtttgggcagttgcttgttttgcacctcagaaacaatgtagggaagatttactaaagagtttcactgaccagctgcgtaaaatctctaaggatgcaggaatgcccatccagggtcagccatgtttctgcaagtatgcacaaggtgcagacagtgtggagcctatgtttaaacatctgaaaatgacttatgtgggcctacagctaatagtggttatcctgcctggaaagacaccagtatatgcggaggtgaaacgtgttggagatacccttctaggtatggccacacagtgtgtccaggtaaaaaatgtagtgaagacctcacctcaaaccctttccaatctttgcctgaagataaatgcaaaacttggaggaattaacaatgtgcttgtgcctcatcaaaggccctcggtgttccagcagcctgtcatcttcctgggagcggatgtcacacaccccccagcaggggatgggaagaaaccttccattgctgctgtggttggcagtatggatggccaccccagccggtactgtgccaccgttcgggtgcagacttcccggcaggagatctcccaagagctcctctacagtcaagaggtcatccaggacctgactaacatggttcgagagctgctgattcagttctacaaatccacacgcttcaaacccactcggatcatctattaccgtggaggggtatctgagggacaaatgaaacaggtagcttggccagaactaatagcaattcgaaaggcatgtattagcttggaagaagattaccggccaggaataacttatattgtggtgcaaaaaagacatcacacacgactcttctgtgcagataaaacagaaagggtagggaaaagtggcaatgtaccagcaggcactacagtggatagtaccatcacacatccatctgagtttgacttttacctctgtagtcatgcaggaattcagggaaccagccgtccctcacattaccaggtcttgtgggatgacaactgcttcactgcagatgaactccagctactgacttaccagctgtgtcacacctatgtgaggtgcactcgctcagtctctattccagcccctgcatattatgcccggcttgtagcatttagggcaaggtatcatctggtggataaagatcatgacagtgcggaaggcagtcatgtgtcaggacagagcaacggccgggatcctcaggccttggctaaggctgtgcaaatccaccatgatacccagcacacgatgtattttgcctgagagtctcagaaaaagaactcaaccaatttggcaccccatgcagcctcaaaatgtttcaaatgcctaccgcctctagatcgagccacgttgacttcaggtggtcttctaccagcagctcggaatagttgcactgaatctatactttgcagcactgtctgatgcgtcaacaaaattgagccatttttttaaagtaatagatactaatagattatcttttctgatgcactggactgaatttttacctcaatgtgcaaaggctgatcagcctgaactttctaaaggactttacaagaagggtttctatggaatattttgctagctgtggtgttcaccgcatccctctagtcttagaagagaagattattccttttttctgtagtcattgagtggggtatatgcataagtgggagagaaaaaccaaacaatctacttcagttcagtgtaactatttaattgtgtgggtccatagactttttaatgaagatttctgactttgccactgtaaatgcctttaatgagcattaatttttgaaagttttacagagttttattagttttactactttatcttattgatctctgcagacttgtgctggtgcaagtacatgctgacaggcaatttgcactatatttggctgcagattcaaataggcagttctcttatttggtcgacttttgtgaatgtgtgacataaacagatgtaatgcatgtcacagtgacggagataacactgccatgataaaagtactcatgtttcccctatttggaaaaaaaaattgcttttagtatttttccaagttttcaaaagtgcccattttatgctgctgtgtggtttgttaaatctaaatgatttttaaacttttctcatagaaacttaactttggcaataaacattttttaaggtctctcctcttccttccccaacaatgtagttttctagatgagatttcagtatgattttatcagctatttcttatatatcataatctggcaatttctgaaaccagtcagaaaagacatatatttccatgcctttttaaagaattatttttacctgttttatattcacagttggtgtcctgtcactttgttttaaaataagctagaaccaggatgcttccttattggaaaggctttgccagtccttaaggtacaatgagtgatgctgcaacttgcaaatgtaccagcatttaaaatttcttttcctgggaatcaaggtaactcacacgactacttgcagtacaaattttttgcttctctttcgacatgaaatgtacttggtgggttttccttccttttattaaactaaaactgtgtggaaaaggttgatttttcttaatagattctggattccactcacagggagatgggattcctttcttgtccaaacaaagggagttgctctaaagcgagcatcagttaaaatgtaggggaaaatgtattctgtatgtagtgtagataatactttgtgaatggacaacagttacatagtgtcttggtagcaccagccagtgtttcccagcccagagtttactgacttgtaattctctatccaggacatcaggagtgagggatggaaaaggggataaaaggcctggagccacactctatatggctgaggaaggagctagggaaagagatagacacaatggggtgaaaacaattttgccgcccctgcctggaaactgctggtggggaaatgatggtgaagggtgtttgcttgaactcatgagacggtccaaatctcataaactagccttctcaaaatcccagcaatataaagcactgtttttcttcagtcgtttaaataaacttgtaaatacattgaagtttacatttccatgtgctgttgatcaacggcgccacctgtgtttgctgagactggtctctgagagagttttatgtcgatcgaggcctgttgctcattaagctgagtgcagacgtccttaatccctgcagatagtgggatgaaagcaagttctgtaaaatgaagcacaacatagccaggagtgaagagatggcagatgttaatttcttaaaattttccttttttttttttttttttgcaaatacctcacttggataatacaaatcaggacatgttggtgaggggctggctgcttggctgctgcttttattcacacttgttcagggagagcacagagaatacccttcagcatggccactctggacccaagaggaggaaaaaacggaagcttttttaggagaaggaggacttgctggaatccaagatgtgaagaactcttggtgactggctggctggccagcgggcaccacacctgcacttgagtgcctcgggcttgcttattaataacgcacagaagaagcatcacttctcaccatctcctggcatgtatggagcagggagcaaggctatgttcccgaaagccctgattagcttgtcttgctctacgctcgacctcgaacaatacagcttgtaagacctcagtcagtcctggtacactggggtaaatcagtgtggtggtggaagaaaagccgggaggcctatttttataggaaaatagtaccattaaaggtgcaatgctgtcattttggacaaaaggaaagaaatttggaagagctgggattattggcaaaaacttgctgaggggtgaatctttagagctaatcactgcagaatcagagttgcagcaatatgattgcaagcaagtctgaatgcatagttttactttaattcggcttgacaatttgaataggtaaccccctcgggactgactgaatcgttatgcatgtgtcaatcaatgggaggtgtgcattctctagaagtagttttaggctgtttggtttggttttggttttgttttttaaatgcagcctgttgaggcactgtcatgtggtgtgaaagatttaaatgtagcaacgctaaagagtaataatttggggataagaagtggggacattggccgggcgcggtggctcacgcctgtaattccagcactttgggaggcctaggtgggcggatcagctgaggtcgagagttcgaggccagtctgaccaacatggtgaaaccccatctctactaaaaatacagaaaattagctgggtctggtggtggatgcctgtaatcccagctactcgggaggctgaggcaggagaattgcttgaacccaggaggtggacggtgcagtgagctattactccagcctgggcaacaagagcgaaactctgtctcaaaaaaaaaaaggggggggggggacattaagagagtggtgatgacccaaatgttgaaccaattatgttttggtggtggtgttcttagctgttgaatcctgaatggtttataaagtgaactagctggcttaatgcagccagcgttctgggcagcagaacatattcattcttactgtaaattctatttgctgcttccaaaggtgatgattttcaagcagacatgttctatatggtctgtgttttaggatctggtgcccagcctctatcagagcttgcctacctggcaaagctgcctacccttcaagtgggaaaatataatccactgtttaacaaggctcaccctctccaccctgtcctaacgaccttttgtgaatgtgctgtgatattttcttgctcaatagcaaggtggtagctctgctttcattttaagaaagtggaggctgagggcattgtatcaatactgttgcaactccaagaagttttccttgtaaaattaaaggaaagatcttgttattgattaaccattttcttatgccttgctattgacatattcatgctctttctacgtctagtggctgaaaatgtttgcatttgttcatttgactaatggtgtgatttttgtttctatattattagacctgtaatgttttaaaatgtattttattaaatttggactggatgtatgtctctagcaatacgaggtactttctaaactattaagggaggggttgtatcctcatgttgagataagatgatggtcgtttaaattttgcaattttttttggcctgcagggatattttgtgtttatgtgtccaaaaaaggaataaattggcattcttgtgccaaaagttgtttttcctgtcaattgtctaataagtatgcagtacactgtaatggcaacatacatggttgctttataaaaacagtttcctcagtatgagaaattttacaaagaacagtggaaaaactttgtgtttttaactcttgggtctccctatttttaaaaattgctatttggtatacaattattatgtgtcaattaaaactaaaataaaacttttaaaaaagaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:192670 -> Molecular function: GO:0003723 [RNA binding] evidence: IEA
            GeneID:192670 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:192670 -> Biological process: GO:0006402 [mRNA catabolic process] evidence: IDA
            GeneID:192670 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
            GeneID:192670 -> Biological process: GO:0007219 [Notch signaling pathway] evidence: TAS
            GeneID:192670 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
            GeneID:192670 -> Biological process: GO:0010467 [gene expression] evidence: TAS
            GeneID:192670 -> Biological process: GO:0035278 [negative regulation of translation involved in gene silencing by miRNA] evidence: IDA
            GeneID:192670 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
            GeneID:192670 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:192670 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
            GeneID:192670 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: TAS
            GeneID:192670 -> Cellular component: GO:0000932 [cytoplasmic mRNA processing body] evidence: IEA
            GeneID:192670 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:192670 -> Cellular component: GO:0035068 [micro-ribonucleoprotein complex] evidence: IEA