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2024-04-24 11:36:54, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_015035 9991 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens zinc fingers and homeoboxes 3 (ZHX3), mRNA. ACCESSION NM_015035 VERSION NM_015035.3 GI:76563911 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 9991) AUTHORS Suehiro,F., Nishimura,M., Kawamoto,T., Kanawa,M., Yoshizawa,Y., Murata,H. and Kato,Y. TITLE Impact of zinc fingers and homeoboxes 3 on the regulation of mesenchymal stem cell osteogenic differentiation JOURNAL Stem Cells Dev. 20 (9), 1539-1547 (2011) PUBMED 21174497 REMARK GeneRIF: ZHX3 is involved in the switch from the undifferentiated state of mesenchymal stem cells to an osteogenic program REFERENCE 2 (bases 1 to 9991) AUTHORS Liu,G., Clement,L.C., Kanwar,Y.S., Avila-Casado,C. and Chugh,S.S. TITLE ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome JOURNAL J. Biol. Chem. 281 (51), 39681-39692 (2006) PUBMED 17056598 REMARK GeneRIF: ZHX proteins 1, 2 and 3 are major transcriptional mediators of podocyte disease Erratum:[J Biol Chem. 2007 Apr 27;282(17):13140] REFERENCE 3 (bases 1 to 9991) AUTHORS Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A. TITLE A germline-specific class of small RNAs binds mammalian Piwi proteins JOURNAL Nature 442 (7099), 199-202 (2006) PUBMED 16751776 REFERENCE 4 (bases 1 to 9991) AUTHORS Lim,J., Hao,T., Shaw,C., Patel,A.J., Szabo,G., Rual,J.F., Fisk,C.J., Li,N., Smolyar,A., Hill,D.E., Barabasi,A.L., Vidal,M. and Zoghbi,H.Y. TITLE A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration JOURNAL Cell 125 (4), 801-814 (2006) PUBMED 16713569 REFERENCE 5 (bases 1 to 9991) AUTHORS Kawata,H., Yamada,K., Shou,Z., Mizutani,T. and Miyamoto,K. TITLE The mouse zinc-fingers and homeoboxes (ZHX) family; ZHX2 forms a heterodimer with ZHX3 JOURNAL Gene 323, 133-140 (2003) PUBMED 14659886 REFERENCE 6 (bases 1 to 9991) AUTHORS Yamada,K., Kawata,H., Shou,Z., Hirano,S., Mizutani,T., Yazawa,T., Sekiguchi,T., Yoshino,M., Kajitani,T. and Miyamoto,K. TITLE Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3 JOURNAL Biochem. J. 373 (PT 1), 167-178 (2003) PUBMED 12659632 REMARK GeneRIF: dimerizes with both ZHX1 and ZHX3, also interacts with the activation domain of the NF-YA REFERENCE 7 (bases 1 to 9991) AUTHORS Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G., Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L., Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M., Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J., Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P., Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y., Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R., Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P., Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L., Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R., Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L., Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K., Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A., Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M., Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L., McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D., Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A., Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J., Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T., Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D., Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M., Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L., Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L., Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and Rogers,J. TITLE The DNA sequence and comparative analysis of human chromosome 20 JOURNAL Nature 414 (6866), 865-871 (2001) PUBMED 11780052 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI458686.1, AB081948.1 and AL022394.3. On Sep 29, 2005 this sequence version replaced gi:40317630. Summary: This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008]. ##Evidence-Data-START## Transcript exon combination :: AB081948.1, AK292415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025084 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-18 BI458686.1 6-23 19-4983 AB081948.1 1-4965 4984-9991 AL022394.3 73625-78632 c FEATURES Location/Qualifiers source 1..9991 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="20" /map="20q12" gene 1..9991 /gene="ZHX3" /gene_synonym="TIX1" /note="zinc fingers and homeoboxes 3" /db_xref="GeneID:23051" /db_xref="HGNC:15935" /db_xref="HPRD:10320" /db_xref="MIM:609598" exon 1..134 /gene="ZHX3" /gene_synonym="TIX1" /inference="alignment:Splign:1.39.8" exon 135..228 /gene="ZHX3" /gene_synonym="TIX1" /inference="alignment:Splign:1.39.8" exon 229..3238 /gene="ZHX3" /gene_synonym="TIX1" /inference="alignment:Splign:1.39.8" misc_feature 235..237 /gene="ZHX3" /gene_synonym="TIX1" /note="upstream in-frame stop codon" CDS 379..3249 /gene="ZHX3" /gene_synonym="TIX1" /note="triple homeobox 1; triple homeobox protein 1; zinc finger and homeodomain protein 3" /codon_start=1 /product="zinc fingers and homeoboxes protein 3" /protein_id="NP_055850.1" /db_xref="GI:28827782" /db_xref="CCDS:CCDS13315.1" /db_xref="GeneID:23051" /db_xref="HGNC:15935" /db_xref="HPRD:10320" /db_xref="MIM:609598" /translation="
MASKRKSTTPCMIPVKTVVLQDASMEAQPAETLPEGPQQDLPPEASAASSEAAQNPSSTDGSTLANGHRSTLDGYLYSCKYCDFRSHDMTQFVGHMNSEHTDFNKDPTFVCSGCSFLAKTPEGLSLHNATCHSGEASFVWNVAKPDNHVVVEQSIPESTSTPDLAGEPSAEGADGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPSQPVGEALPKLSTGEMEVREGDHSFINGAVPVSQASASSAKNPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHVHQPLPTAKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAALPGHVVGQPEGTGGGLLVTQPLMANGLQATSSPLPLTVTSVPKQPGVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRAMIPGDHSSIIIDSVPEVSFSPSSKVPEVTCIPTTATLATHPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRSETKMTRREIDSWFSERRKKVNAEETKKAEENASQEEEEAAEDEGGEEDLASELRVSGENGSLEMPSSHILAERKVSPIKINLKNLRVTEANGRNEIPGLGACDPEDDESNKLAEQLPGKVSCKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLYEEDLQNLCDKTQMSSQQVKQWFAEKMGEETRAVADTGSEDQGPGTGELTAVHKGMGDTYSEVSENSESWEPRVPEASSEPFDTSSPQAGRQLETD
"
misc_feature 379..699
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H4I2.3);
Region: Required for nuclear localization"
misc_feature 1102..1842
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H4I2.3);
Region: Required for homodimerization and interaction with
NFYA"
misc_feature 1285..1884
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H4I2.3);
Region: Required for repressor activity"
misc_feature 1318..1467
/gene="ZHX3"
/gene_synonym="TIX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(1360..1362,1378..1380,1417..1419,1423..1428,
1435..1440,1444..1452,1456..1461)
/gene="ZHX3"
/gene_synonym="TIX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(1426..1428,1435..1440,1447..1449)
/gene="ZHX3"
/gene_synonym="TIX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 1867..2043
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H4I2.3);
Region: Required for nuclear localization"
misc_feature 1876..2037
/gene="ZHX3"
/gene_synonym="TIX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(1876..1878,1996..1998,2005..2010,2017..2019)
/gene="ZHX3"
/gene_synonym="TIX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature order(1879..1881,1930..1932,1948..1950,1987..1989,
1993..1998,2005..2010,2014..2022,2026..2031)
/gene="ZHX3"
/gene_synonym="TIX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature 2239..2370
/gene="ZHX3"
/gene_synonym="TIX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(2350..2352,2359..2364)
/gene="ZHX3"
/gene_synonym="TIX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 2416..2418
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H4I2.3); phosphorylation site"
misc_feature 2674..2847
/gene="ZHX3"
/gene_synonym="TIX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(2674..2685,2689..2691,2740..2742,2758..2760,
2797..2799,2803..2808,2815..2820,2824..2832,2836..2841)
/gene="ZHX3"
/gene_synonym="TIX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(2677..2679,2686..2688,2806..2808,2815..2820,
2827..2829)
/gene="ZHX3"
/gene_synonym="TIX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 2899..3057
/gene="ZHX3"
/gene_synonym="TIX1"
/note="Homeodomain leucine-zipper encoding, Homez; Region:
Homez; pfam11569"
/db_xref="CDD:152005"
misc_feature 3214..3216
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H4I2.3); phosphorylation site"
misc_feature 3214..3216
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
STS 1426..1798
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="ZHX3"
/db_xref="UniSTS:505898"
variation 1693
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="a"
/replace="g"
/db_xref="dbSNP:35600883"
variation 2587
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="a"
/replace="g"
/db_xref="dbSNP:34073395"
variation 3036
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="a"
/replace="g"
/db_xref="dbSNP:34229622"
exon 3239..9991
/gene="ZHX3"
/gene_synonym="TIX1"
/inference="alignment:Splign:1.39.8"
STS 3360..3559
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="WI-20100"
/db_xref="UniSTS:50785"
STS 3454..3553
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="A002B15"
/db_xref="UniSTS:79105"
STS 3454..3553
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="G19883"
/db_xref="UniSTS:79104"
polyA_signal 3591..3596
/gene="ZHX3"
/gene_synonym="TIX1"
polyA_site 3610
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
polyA_site 3619
/gene="ZHX3"
/gene_synonym="TIX1"
/experiment="experimental evidence, no additional details
recorded"
variation 4734
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="c"
/replace="g"
/db_xref="dbSNP:11548449"
STS 4993..5104
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="RH12301"
/db_xref="UniSTS:59251"
STS 6021..6114
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="D20S571E"
/db_xref="UniSTS:32919"
STS 6041..6175
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="RH12290"
/db_xref="UniSTS:17400"
STS 8528..8748
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="D13S1553"
/db_xref="UniSTS:473482"
STS 8580..8694
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="D10S16"
/db_xref="UniSTS:155756"
variation 9353
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1057825"
variation 9401
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="a"
/replace="t"
/db_xref="dbSNP:12609"
STS 9735..9915
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="D20S526E"
/db_xref="UniSTS:4087"
STS 9824..9944
/gene="ZHX3"
/gene_synonym="TIX1"
/standard_name="STS-N25688"
/db_xref="UniSTS:56271"
variation 9838
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1057891"
polyA_signal 9968..9973
/gene="ZHX3"
/gene_synonym="TIX1"
polyA_site 9985
/gene="ZHX3"
/gene_synonym="TIX1"
variation 9986
/gene="ZHX3"
/gene_synonym="TIX1"
/replace="a"
/replace="t"
/db_xref="dbSNP:3178978"
polyA_site 9991
/gene="ZHX3"
/gene_synonym="TIX1"
ORIGIN
gtgatagccgtcaaaggcagcaaatagactgaatgaaagatgagcttctgcctttatatccttctctcctgctacccaactcattgtggtgaaggaaaaagaaaacgcgggtggagactgcactatatgcttaggactgaaatgcaactgcagaagcaacatgtgaccttttagagatgcttgtgggactgcataaagtgaagagggaaactggaaaaaaacaatgaaattgaatagggaaaacctgctttctgcaaacaactgaaaaagctgcatttagaaactgtttctttggccctcatcgagaagctggaacttgtattgttaggccccttatgggacaagctctcaactgctgatcacccagtgattgtcaccatggccagcaagaggaaatccaccacaccatgcatgatcccagtgaagactgtggtgttgcaagatgccagcatggaggcccagcccgctgagaccttgcctgaaggaccccagcaggatctgcccccagaagcatctgctgccagcagtgaggcagcacagaaccccagcagtactgatggctctacactggccaatgggcatcggagcactttagatggctatttatattcctgtaaatactgcgatttcagatcccatgacatgacccaatttgtgggacatatgaactcagagcacacagactttaataaagacccaacctttgtatgcagtgggtgcagttttctggcaaaaacccctgaggggctttccttgcacaatgccacatgtcactccggggaagccagctttgtgtggaacgtggccaagccagacaatcatgtggttgtggagcagagcatccctgagagcaccagcactcctgacctagcgggtgagcccagtgctgaaggggctgatggacaggcagaaatcatcattaccaaaactccaatcatgaagataatgaaaggcaaagctgaagccaaaaaaattcatacactcaaggagaatgtccctagccagcctgtgggtgaggccttaccaaagctgtcgactggagaaatggaggtgagagagggggaccattccttcatcaatggggcagttccagtcagccaggcatctgccagctctgcaaaaaacccccatgccgccaacgggcccctgataggaacagtgccagttttgccagctggcatagcacagttcctctccctccagcagcagcccccagtgcatgcccaacaccatgtccaccagccactgcccacggccaaggcccttcccaaagtgatgatccccctgagcagcattccaacgtacaatgcagccatggactctaacagcttcctgaagaactccttccacaagttcccctaccccaccaaagccgagctctgctatttgactgtggtgaccaagtatccagaagaacagctcaagatctggttcacagcccaaaggctgaagcaggggatcagctggtcccctgaggagattgaggatgcccggaaaaagatgttcaatacagtcatccagtctgtgcctcagcccacaattacggttctaaataccccactcgtcgccagtgctggcaatgtccagcatctcatccaggccgctcttccaggtcacgttgtggggcagccagagggtacaggagggggacttctggtcactcagccattgatggccaatgggttgcaagcaacaagttcccctctccccctcacggtgacatccgtccccaagcagccaggtgtggcacccattaacactgtgtgttcaaatacaacgtcagctgtgaaggtggtcaatgcggcccagtcgctcctcacggcctgccccagcataacctcccaagccttccttgatgctagcatctacaaaaataagaaatctcatgaacagctgtcagctctgaaagggagcttctgtcggaaccagttcccagggcagagcgaagttgaacatctcacaaaagtgacgggcctcagtaccagagaggtgcggaaatggttcagtgatcgtagataccactgccggaacttgaagggctccagagcgatgatacctggagatcacagttccatcatcattgactctgtgccagaggtgtccttctccccatcgtccaaggtccctgaggtaacctgcattccgacaacagccacactagcaacccacccttctgccaaacgacaatcttggcaccagactcctgacttcacaccaaccaaatacaaggagagagcccctgagcagctcagagccctggagagcagttttgcacaaaaccctcttcctcttgatgaggaactggaccgcctgagaagtgaaaccaaaatgacccgacgagaaattgatagctggttttcagagagacggaaaaaagtgaatgctgaggagaccaagaaggctgaggagaatgcctctcaggaggaagaggaggctgctgaggatgagggtggagaagaggatttggccagtgagctaagggtctctggtgaaaatggctctctggaaatgcccagcagccatatcttggcagagcgcaaagtcagccccattaaaatcaacctgaagaacctgagggtcactgaagccaatggcaggaacgagattccagggctgggtgcctgtgaccctgaggatgatgagtcaaacaaactggcagagcagctcccaggcaaagtgagctgcaaaaagactgcccagcagcggcacttgctgcggcagctctttgtccagacacagtggccaagcaaccaggactatgactccatcatggcccagacgggtctgccacggccagaggtggtgcgctggtttggagatagcaggtacgcactgaagaacggccaactcaaatggtacgaagactataagcgaggcaacttcccaccagggctactggtcattgcccctggcaaccgggagctcctgcaggactattacatgacacacaagatgctgtatgaagaggacctgcagaacctctgtgacaagacccagatgagctcccagcaggtcaagcagtggtttgctgagaaaatgggggaggagaccagagccgtggcagacacaggcagtgaggaccagggccctggtactggtgagctcacagcagttcacaaagggatgggtgacacctattcagaggtgtctgagaacagtgagtcgtgggagccccgtgtccctgaggccagctcagagccctttgacacatcgagtccccaggctggacgtcagctcgaaacagactgaatttgatctgattaatgtgaaggactggccagtctgggaaaccgcctgccacgtggaagagccaaacccgactctctgctgccacatgccgttcccatgcccggctgctgggcacctgggagagcttccagaatcctcgcagacagcccagagcctgccgctaccctcggcctgcccaccaccaagcaagcagcaagcaagatggggttctcatcagttcttcctcccacaatgtaggacctttcctttaccttccaatggataaaatagttcagagttcatagtcatattcatagacacagaatcaagcttttaacatatacatccacctctatatgttaaataaaacatcagattatcaacactgtcattacgtagaaactttggttagccaagcagtgcattgtcagttacgtcatctctaaaaatgacctgtgtctgttctctggggattgctgggtcacaggtgcccctcaccttccacagtcaggcagggaagttataggcacaaagctacgtctggaacccctttgtgccccctttgtgttcctcaaggaagcagtacctttgaagagatctctgctgcattaagtgatgaccggctacgtttcatgtcaggcttgctttgccttgtgggctactcagtgcagaacctgctgtaaccctcagttcaaaaaatggactggcaatgtgattagcgttggatgctttaccattctctttagttgttaccgtaattctgctttttcatgggagtttgaatcatggaccataacttttcagttatcagatcaactaaagaaacatttgttgttaagcctaatgtgctgacctatgtgcctgcattttttttttaatctagacatgtttggagtgagagaaagatggaaaaaagacatggggtagggacgtaagtggaaatctatagccacagcctgaagctttgaccactgcggttttcagagccctttctccacactcatttcagagcctcctatggtttgggaaggaataacacactggcccattagtaagggtgaaggctggagggatttgttgacttcttggaattatcagaggtagggtggtctttagcacaaagacttgcatgcagagatccctggcagaacacccagagtgcccgtggctcccaccccagggtctggccggtgtgctggatgcatgcccaagggtgctgggcatcactggtccttgtgaggatgcttttaaagttttatatttatgtccccaaacttggaaacaagaactctactttagcctaaccctcatgtccttttttgaattgagaaaattacaggaaatggtgcctttgaaaattagaaaacttgcttacagagctgttctaaatggtaaatcctcaatttccccaagaccggttgctctgagagtagctggtaaagaggggcgaactaaagacctgtccacctgtagctccgctcatttcttagaaaccacctgcttcccagagtgccaagccacaagtaccaggcttcgtgggcacagacacctcctgggctgggcagagtgacagtgctagaagaccccagagagagggcaagggctttgggcaagaagcactggtggtgttttagggaccgtccttctcccctacccagggaactggacctggcagggcaccgtgctcatgtggctccaaggacaagcatggcggtggccccttctgccttccaggagaggtcttgcttttgaaaccaaaatcatgttcttctaaagtgtcatcttctgccctccctgtcccaatagggaccacatcttatttgtctcaaacagggacttgtgagtacttggcaagttttgcagcctatttttgtattcttaatttggggagtaaagatgtttggtctcaaaaacctttgaggaattgccaagaatggcgagtgattgctttccttcagagaacagacacttggaatttctccttttagtgtttatatacgtgcagattaatttatatatatatatatacacacacacatatacagtataaatactcatttgattctcgtaaaacgcgcatctggcgtgtgcagttgagaaacttggtggcacatgggtgttgggggagtagcctgtgttggagggacaccagtgcactaggcagctggggcggcccaggctgaagccatctccgggtgtctgagaaaccacccagtgcctcacctccagatcctgctggcatcacctccagagccctgcatgcactggctgaagagttggtctgtggagaggattttcttggttacttgtattcacggttaatttacaacccaaacagcaaaacacagttggtggacaagttcatgcaggacctacagtgacccagccatgggcactagctcatctttcaggtggaaaagtacagtgctgcctgccctggtatgtttttcttatagatgttagccctgcccaacagccagggctacactacaaaaggcaagaatgcccatgtaaggagcccagcagtctggacagatccttcttcctctgctgttggatgagagtgagtgagtatgctctggaccttatccttgaaagatgatcaaaagcgatgatgagggaggcagtcatcacgcaggtgcttaaagggacattgtaggaggtactcaagggtttgggggcaaaaccctgaatccagccagtcgtgcacagagacacacccacactagcccagtggcagtgggggatgtgggatggcagcagccaggtatgtagccctgtcacaggacagctcactgtggttttgcacactgcctaagggttaaattgtgttgttgccttcagtagaaggcatttgtgggctgcagagttgagagttgggtgaggttagtctctcctgaagaaaaagcctataaaaagtggctaatcttatcccttttctctgtatgcagttggactcgtcagagatagtaaaatcatcttttagtgtttttttgttgctgatgtcttgtacccatttgttttttacatggggttgtagatcgagttctcaaaggtgaaaccagatgatcattctgataaaggaaatttaaatttgatacatatgctttgtatattttgattacttgttttcgtttttgactataaaggagcttttttattttgggaggggaggagtgtcatttttgagaatcttgggttcctgaaaaagaacgccctagttggatggcttgccagggccttggggtttggtagtgattgtacaacttaaagctcctttctcttggctgagtgacaggtggctgttcaggtggaccaaagcaccttgacacaaggactccacactgtgctctctagtagcacaaggaggaagttggacagaacattgggtagtgccttgcgggctcacacatgtactagtggtctcatctccagctagccttgggaggccgtcccaccaggaaatctctctattccgtagcctgagatgtgcccttgtgggttttatcctgctcagtcagtggcctaggggcaggtcctgtgttctctccctctctctcctggctctgggacatctgtccctggctgcctttcatggaggaaggacactggcctttctggttggatgctgtgtggatgctctctgcttgagcctcgtggtctcttgtctctttttggaccaatatcctcagattggtgcagctttttcagttcagatatcacaccccaagtggataaaggcaacttgcaggagaggagagccagccaagaagaaaattttaaaaccaaacctcgtttaggattttcctaaagtcatcttctcttttttcttgctcagagtttacctgggagatttcaccagtttgactcaccatttgcagatgtgcttttgtattaaatttaaattttcacatatcacatccattctcaaggtagttatatgctggagaagaaaaatcctctagacacatgaaggcccacatagtcaagtcttccagggcaaagccagcagcccacccaggtcaggtagccagcagggctcagttcccctcactccagacacggaccctcctcttcagggtctcttgacccagcttccttctctccttttacctgagagcacagacctctctcagccagcctgcccagaccacggggggctactcccatgtagtttggggagcacttgatctcagaaaagctccattgtctgagcaaatgggcagttgtggagctcaagcctttctcctgtgctcaagtcccttccccaagcaaggcttcaacctcatctacccaccatgtagttttctctggccatttaagtggggcggcagggacatggttgggccatgccacaccagggctggtgaggcaaccagttttgattttgacagagtggctggaggaaaagtggcaatcaaggtgctgcttggtttgctctgagtgcaaatggaaccaacaggtttctgctgcaatctgtgtgttcccagtgccaggtcacaccaggaggggtggggcagggctaaccaagtggtctctgaactcaccgagcgtctgcacttggttgtgaagttaatgggagtacagagagcgtctggccttggagaggggttgagagcctcctttttggttcttcattcctgagctcttgcctgcccacaaatctgacctctttgaatggggacgcagtccttcaacagagaagtttctatggcaaagaagtttctatttagctctagatccagcagagtcatccattctaactgccctgaagtctagagcaggggagggaacccagaggctggggatgagactaggcagaccctggttaccatatggacaaggacaggggaaagcacccccttcctcaatttctgaaagttctatctttgggttcgcaggactttgaggatgataaagaacatataggtactagcttgttgttgctggtccaaagcttccacagccctgagaatttggctttcgtggctgctctggcagctgagcgaagggaggaaggcagccgctctggtggggactctaggcaccttccctgctgtccacttggataggcggtgagccccagggtactgagaggagcctgagcatttacctgccattagtgcctcttccttcaggagactggcttgaaacgtgtgttcatgtgcgcgtgcacacacacacatgagcacctgtatgtgttaatgaatagtttttcttggttaatgctttttaacttctgttcctttccgtaagtggatgattcaaaattaacgtgacttggctgggcgcagtggctcacacctgtaatcccagcactttgggaggccaagggaggcggatcacctgaggtcaggagttcgagaccagcctgatcggcatggtgaaaccccgtttctactaaaaatacaaaaattagccgggcgtggtggtgcgcgcctgtaatcccagctactcaggaggctgaggaaggagaatcacttgaacccgggaggtggaggttgcagtgagctgagatcgtgccactgcactccagcctgggcgacagagcgaaactccgtctcaaaaaaaaaaaaaaaacttaatgtgactggagttaaaagtgaaatgtcaggttgtttagtcactgaatagagagctacaagtgcttggtctttcccaagaatcaaacctgagtagaaatacatttaaaagaaaaatctacatggtacctatgaatcctgtaatttgtttagggagatcttgtcactcatccctggttcctgcccatactgtttggtctcgttcttgcagtttgcttggaacagggccagagccccacatgagattgtcagcaggagtgaggagcgccagtccctactcctcagcagggacccagcacagcaatccggttgttctcggttagactgggtcggggccaggggagaagcagtcacccctgtgtagagggttcccgctgtgcttctgagcagttgctttgttcagaagtgttaggagggtcagattgtgccataattgttattaaagagaaaacacgcccaccttcctttctcccctgctggccattgttcattgagttttactgagggcagcctttgtggaagtcagggaggttgccaaaggcctgtagatgcctcctgacaaggtcttgattcctggttttctagcacccatttgcattttggtcttcagcacaaagccttgttccctgtggccggacttctgggcaataagactggggagtgactgttgagcagtctgctgtcaggagagatggctgaaaaggtgatcatcttggtgctaaacaagtaagaggcaactgccctgtttttgtttgttttgaggcacaatgaaactttagccaaactctgcaagagggtcccatctcctgccatggccaggtgtgagagaccaaaccgagaaaacagcatactctatcacttaagccttgggtagaatgggaattctttaccctgggtaaacgttttaacaaaaaaatggaacttaacttcggtttggactgtggtcgtgctgaggcaggagtggggttgccctcttggggctgaatctccaggcctcacgaggtcccctgtggggatgctgctatttctaagatgcaaattgcacatttcctagattttgtatctgtggatttggataagggaggggaacacggacaaattgcttgtacaatttgaaatgggcctcaatggtacttcaaaccttttgattattcctaaataaaaacataaatatatttcac
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23051 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:23051 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: IEA
GeneID:23051 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:23051 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: IDA
GeneID:23051 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
GeneID:23051 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:23051 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IDA
GeneID:23051 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IEA
GeneID:23051 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:23051 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
GeneID:23051 -> Biological process: GO:0045669 [positive regulation of osteoblast differentiation] evidence: IMP
GeneID:23051 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IDA
GeneID:23051 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:23051 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:23051 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
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