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2024-04-18 15:57:08, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006901 8722 bp mRNA linear PRI 16-JUN-2013
DEFINITION Homo sapiens myosin IXA (MYO9A), mRNA.
ACCESSION NM_006901
VERSION NM_006901.3 GI:365192551
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8722)
AUTHORS Luykx,J.J., Bakker,S.C., Lentjes,E., Neeleman,M., Strengman,E.,
Mentink,L., Deyoung,J., de Jong,S., Sul,J.H., Eskin,E., van
Eijk,K., van Setten,J., Buizer-Voskamp,J.E., Cantor,R.M., Lu,A.,
van Amerongen,M., van Dongen,E.P., Keijzers,P., Kappen,T.,
Borgdorff,P., Bruins,P., Derks,E.M., Kahn,R.S. and Ophoff,R.A.
TITLE Genome-wide association study of monoamine metabolite levels in
human cerebrospinal fluid
JOURNAL Mol. Psychiatry (2013) In press
PUBMED 23319000
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 8722)
AUTHORS Omelchenko,T. and Hall,A.
TITLE Myosin-IXA regulates collective epithelial cell migration by
targeting RhoGAP activity to cell-cell junctions
JOURNAL Curr. Biol. 22 (4), 278-288 (2012)
PUBMED 22305756
REMARK GeneRIF: Depletion of myosin-IXA in collectively migrating cells
led to altered organization of the actin cytoskeleton and
tension-dependent disruption of cell-cell adhesions, followed by an
inability to form new adhesions resulting in cell scattering.
REFERENCE 3 (bases 1 to 8722)
AUTHORS Lango Allen,H., Estrada,K., Lettre,G., Berndt,S.I., Weedon,M.N.,
Rivadeneira,F., Willer,C.J., Jackson,A.U., Vedantam,S.,
Raychaudhuri,S., Ferreira,T., Wood,A.R., Weyant,R.J., Segre,A.V.,
Speliotes,E.K., Wheeler,E., Soranzo,N., Park,J.H., Yang,J.,
Gudbjartsson,D., Heard-Costa,N.L., Randall,J.C., Qi,L., Vernon
Smith,A., Magi,R., Pastinen,T., Liang,L., Heid,I.M., Luan,J.,
Thorleifsson,G., Winkler,T.W., Goddard,M.E., Sin Lo,K., Palmer,C.,
Workalemahu,T., Aulchenko,Y.S., Johansson,A., Zillikens,M.C.,
Feitosa,M.F., Esko,T., Johnson,T., Ketkar,S., Kraft,P., Mangino,M.,
Prokopenko,I., Absher,D., Albrecht,E., Ernst,F., Glazer,N.L.,
Hayward,C., Hottenga,J.J., Jacobs,K.B., Knowles,J.W., Kutalik,Z.,
Monda,K.L., Polasek,O., Preuss,M., Rayner,N.W., Robertson,N.R.,
Steinthorsdottir,V., Tyrer,J.P., Voight,B.F., Wiklund,F., Xu,J.,
Zhao,J.H., Nyholt,D.R., Pellikka,N., Perola,M., Perry,J.R.,
Surakka,I., Tammesoo,M.L., Altmaier,E.L., Amin,N., Aspelund,T.,
Bhangale,T., Boucher,G., Chasman,D.I., Chen,C., Coin,L.,
Cooper,M.N., Dixon,A.L., Gibson,Q., Grundberg,E., Hao,K., Juhani
Junttila,M., Kaplan,L.M., Kettunen,J., Konig,I.R., Kwan,T.,
Lawrence,R.W., Levinson,D.F., Lorentzon,M., McKnight,B.,
Morris,A.P., Muller,M., Suh Ngwa,J., Purcell,S., Rafelt,S.,
Salem,R.M., Salvi,E., Sanna,S., Shi,J., Sovio,U., Thompson,J.R.,
Turchin,M.C., Vandenput,L., Verlaan,D.J., Vitart,V., White,C.C.,
Ziegler,A., Almgren,P., Balmforth,A.J., Campbell,H., Citterio,L.,
De Grandi,A., Dominiczak,A., Duan,J., Elliott,P., Elosua,R.,
Eriksson,J.G., Freimer,N.B., Geus,E.J., Glorioso,N., Haiqing,S.,
Hartikainen,A.L., Havulinna,A.S., Hicks,A.A., Hui,J., Igl,W.,
Illig,T., Jula,A., Kajantie,E., Kilpelainen,T.O., Koiranen,M.,
Kolcic,I., Koskinen,S., Kovacs,P., Laitinen,J., Liu,J., Lokki,M.L.,
Marusic,A., Maschio,A., Meitinger,T., Mulas,A., Pare,G.,
Parker,A.N., Peden,J.F., Petersmann,A., Pichler,I.,
Pietilainen,K.H., Pouta,A., Ridderstrale,M., Rotter,J.I.,
Sambrook,J.G., Sanders,A.R., Schmidt,C.O., Sinisalo,J., Smit,J.H.,
Stringham,H.M., Bragi Walters,G., Widen,E., Wild,S.H.,
Willemsen,G., Zagato,L., Zgaga,L., Zitting,P., Alavere,H.,
Farrall,M., McArdle,W.L., Nelis,M., Peters,M.J., Ripatti,S., van
Meurs,J.B., Aben,K.K., Ardlie,K.G., Beckmann,J.S., Beilby,J.P.,
Bergman,R.N., Bergmann,S., Collins,F.S., Cusi,D., den Heijer,M.,
Eiriksdottir,G., Gejman,P.V., Hall,A.S., Hamsten,A., Huikuri,H.V.,
Iribarren,C., Kahonen,M., Kaprio,J., Kathiresan,S., Kiemeney,L.,
Kocher,T., Launer,L.J., Lehtimaki,T., Melander,O., Mosley,T.H. Jr.,
Musk,A.W., Nieminen,M.S., O'Donnell,C.J., Ohlsson,C., Oostra,B.,
Palmer,L.J., Raitakari,O., Ridker,P.M., Rioux,J.D., Rissanen,A.,
Rivolta,C., Schunkert,H., Shuldiner,A.R., Siscovick,D.S.,
Stumvoll,M., Tonjes,A., Tuomilehto,J., van Ommen,G.J., Viikari,J.,
Heath,A.C., Martin,N.G., Montgomery,G.W., Province,M.A., Kayser,M.,
Arnold,A.M., Atwood,L.D., Boerwinkle,E., Chanock,S.J., Deloukas,P.,
Gieger,C., Gronberg,H., Hall,P., Hattersley,A.T., Hengstenberg,C.,
Hoffman,W., Lathrop,G.M., Salomaa,V., Schreiber,S., Uda,M.,
Waterworth,D., Wright,A.F., Assimes,T.L., Barroso,I., Hofman,A.,
Mohlke,K.L., Boomsma,D.I., Caulfield,M.J., Cupples,L.A.,
Erdmann,J., Fox,C.S., Gudnason,V., Gyllensten,U., Harris,T.B.,
Hayes,R.B., Jarvelin,M.R., Mooser,V., Munroe,P.B., Ouwehand,W.H.,
Penninx,B.W., Pramstaller,P.P., Quertermous,T., Rudan,I.,
Samani,N.J., Spector,T.D., Volzke,H., Watkins,H., Wilson,J.F.,
Groop,L.C., Haritunians,T., Hu,F.B., Kaplan,R.C., Metspalu,A.,
North,K.E., Schlessinger,D., Wareham,N.J., Hunter,D.J.,
O'Connell,J.R., Strachan,D.P., Wichmann,H.E., Borecki,I.B., van
Duijn,C.M., Schadt,E.E., Thorsteinsdottir,U., Peltonen,L.,
Uitterlinden,A.G., Visscher,P.M., Chatterjee,N., Loos,R.J.,
Boehnke,M., McCarthy,M.I., Ingelsson,E., Lindgren,C.M.,
Abecasis,G.R., Stefansson,K., Frayling,T.M. and Hirschhorn,J.N.
TITLE Hundreds of variants clustered in genomic loci and biological
pathways affect human height
JOURNAL Nature 467 (7317), 832-838 (2010)
PUBMED 20881960
REFERENCE 4 (bases 1 to 8722)
AUTHORS Saeki,N., Tokuo,H. and Ikebe,M.
TITLE BIG1 is a binding partner of myosin IXb and regulates its
Rho-GTPase activating protein activity
JOURNAL J. Biol. Chem. 280 (11), 10128-10134 (2005)
PUBMED 15644318
REFERENCE 5 (bases 1 to 8722)
AUTHORS Gorman,S.W., Haider,N.B., Grieshammer,U., Swiderski,R.E., Kim,E.,
Welch,J.W., Searby,C., Leng,S., Carmi,R., Sheffield,V.C. and
Duhl,D.M.
TITLE The cloning and developmental expression of unconventional myosin
IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at
chromosome 15q22-q23
JOURNAL Genomics 59 (2), 150-160 (1999)
PUBMED 10409426
REFERENCE 6 (bases 1 to 8722)
AUTHORS Bement,W.M., Hasson,T., Wirth,J.A., Cheney,R.E. and Mooseker,M.S.
TITLE Identification and overlapping expression of multiple
unconventional myosin genes in vertebrate cell types
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 91 (14), 6549-6553 (1994)
PUBMED 8022818
REMARK Erratum:[Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11767. PMID:
7972138]
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB100556.1, BC060886.1,
AC020779.10, BC150294.1, BC140869.1, AC022872.4 and AF117888.1.
On Dec 22, 2011 this sequence version replaced gi:156119614.
Summary: This gene encodes a member of the myosin superfamily. The
protein represents an unconventional myosin; it should not be
confused with the conventional non-muscle myosin-9 (MYH9).
Unconventional myosins contain the basic domains of conventional
myosins and are further distinguished from class members by their
tail domains. They function as actin-based molecular motors.
Mutations in this gene have been associated with Bardet-Biedl
Syndrome. [provided by RefSeq, Dec 2011].
##Evidence-Data-START##
Transcript exon combination :: AF117888.1, BC140869.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-18 DB100556.1 1-18
19-91 BC060886.1 1-73
92-100 AC020779.10 54891-54899 c
101-331 BC150294.1 2-232
332-4068 BC140869.1 1-3737
4069-4262 AC022872.4 163489-163682
4263-8446 BC140869.1 3932-8115
8447-8722 AF117888.1 8198-8473
FEATURES Location/Qualifiers
source 1..8722
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q22-q23"
gene 1..8722
/gene="MYO9A"
/note="myosin IXA"
/db_xref="GeneID:4649"
/db_xref="HGNC:7608"
/db_xref="MIM:604875"
exon 1..420
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 421..1331
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
STS 437..572
/gene="MYO9A"
/standard_name="RH68081"
/db_xref="UniSTS:20020"
misc_feature 453..455
/gene="MYO9A"
/note="upstream in-frame stop codon"
CDS 492..8138
/gene="MYO9A"
/note="myosin-IXa; unconventional myosin-9a"
/codon_start=1
/product="unconventional myosin-IXa"
/protein_id="NP_008832.2"
/db_xref="GI:156119615"
/db_xref="CCDS:CCDS10239.1"
/db_xref="GeneID:4649"
/db_xref="HGNC:7608"
/db_xref="MIM:604875"
/translation="
MNINDGGRRRFEDNEHTLRIYPGAISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKCYVLAEVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGSLQSWLRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNIHRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGILTRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSPKFDSRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEERQKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAPSSYQSKQRVERPSSLLSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKELSKTDRMGTQLNVACKLSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIPLVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQAKLHKTMSQGEITKLAVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDELAAYHPTPPLSPELPGSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGKSIRYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQIENLQKEKEELTFEMLVLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLALSSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSHGTRKLFQIYSKSPFYRAASGNEALGMEGPLGQTKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTVMSGRRKTVDPDCTSNQQLALFGNNEFMV
"
misc_feature 507..821
/gene="MYO9A"
/note="Ubiquitin-like proteins; Region: UBQ; cl00155"
/db_xref="CDD:212176"
misc_feature order(627..629,675..677,819..821)
/gene="MYO9A"
/note="charged pocket; other site"
/db_xref="CDD:176352"
misc_feature order(681..692,813..818)
/gene="MYO9A"
/note="hydrophobic patch; other site"
/db_xref="CDD:176352"
misc_feature 909..2633
/gene="MYO9A"
/note="Myosin and Kinesin motor domain. These ATPases
belong to the P-loop NTPase family and provide the driving
force in myosin and kinesin mediated processes; Region:
Motor_domain; cl00286"
/db_xref="CDD:212601"
misc_feature 918..>2564
/gene="MYO9A"
/note="Myosin. Large ATPases; Region: MYSc; smart00242"
/db_xref="CDD:197599"
misc_feature 1014..1076
/gene="MYO9A"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (B2RTY4.2);
transmembrane region"
misc_feature order(1050..1055,1212..1235)
/gene="MYO9A"
/note="ATP-binding site [chemical binding]; other site"
/db_xref="CDD:73261"
misc_feature <3159..3548
/gene="MYO9A"
/note="Myosin and Kinesin motor domain. These ATPases
belong to the P-loop NTPase family and provide the driving
force in myosin and kinesin mediated processes; Region:
Motor_domain; cl00286"
/db_xref="CDD:212601"
misc_feature 3210..3245
/gene="MYO9A"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (B2RTY4.2);
Region: Actin-binding (By similarity)"
misc_feature 3552..3977
/gene="MYO9A"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (B2RTY4.2);
Region: Neck or regulatory domain"
misc_feature 3978..8024
/gene="MYO9A"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (B2RTY4.2);
Region: Tail"
misc_feature 6489..6635
/gene="MYO9A"
/note="Protein kinase C conserved region 1 (C1) .
Cysteine-rich zinc binding domain. Some members of this
domain family bind phorbol esters and diacylglycerol, some
are reported to bind RasGTP. May occur in tandem
arrangement. Diacylglycerol (DAG) is a second...; Region:
C1; cd00029"
/db_xref="CDD:28911"
misc_feature order(6489..6491,6528..6530,6537..6539,6576..6578,
6585..6587,6600..6602,6609..6611,6633..6635)
/gene="MYO9A"
/note="zinc binding sites [ion binding]; other site"
/db_xref="CDD:28911"
misc_feature order(6510..6512,6519..6524,6549..6569)
/gene="MYO9A"
/note="putative DAG/PE binding site; other site"
/db_xref="CDD:28911"
misc_feature order(6519..6521,6525..6527)
/gene="MYO9A"
/note="putative RAS interaction site [polypeptide
binding]; other site"
/db_xref="CDD:28911"
misc_feature 6672..7229
/gene="MYO9A"
/note="RhoGAP_myosin_IXA: RhoGAP (GTPase-activator protein
[GAP] for Rho-like small GTPases) domain present in
myosins IXA. Class IX myosins contain a characteristic
head domain, a neck domain and a tail domain which
contains a C6H2-zinc binding motif and a...; Region:
RhoGAP_myosin_IXA; cd04406"
/db_xref="CDD:63875"
misc_feature 6708..7232
/gene="MYO9A"
/note="GTPase-activator protein for Rho-like GTPases;
Region: RhoGAP; smart00324"
/db_xref="CDD:197653"
misc_feature order(6783..6785,6894..6896,6906..6908,7113..7115,
7122..7127,7200..7202)
/gene="MYO9A"
/note="putative GTPase interaction site [polypeptide
binding]; other site"
/db_xref="CDD:63875"
misc_feature 6783..6785
/gene="MYO9A"
/note="catalytic residue [active]"
/db_xref="CDD:63875"
variation 973
/gene="MYO9A"
/replace="c"
/replace="t"
/db_xref="dbSNP:2929516"
exon 1332..1426
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 1427..1489
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 1490..1589
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 1590..1646
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 1647..1744
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 1745..1871
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 1872..1961
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 1962..2078
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 2079..2213
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 2214..2335
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 2336..2477
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
variation 2417
/gene="MYO9A"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:2306487"
exon 2478..2673
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 2674..2793
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 2794..2869
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 2870..3013
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3014..3053
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3054..3176
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3177..3257
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3258..3368
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3369..3491
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3492..3641
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3642..3961
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 3962..5533
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 5534..5633
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 5634..5746
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 5747..5889
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 5890..6113
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 6114..6230
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 6231..6422
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
variation 6289
/gene="MYO9A"
/replace="c"
/replace="t"
/db_xref="dbSNP:3203994"
exon 6423..6470
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 6471..6582
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 6583..6644
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 6645..6837
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 6838..6966
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 6967..7072
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 7073..7204
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 7205..7328
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 7329..7531
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 7532..7674
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
exon 7675..8708
/gene="MYO9A"
/inference="alignment:Splign:1.39.8"
STS 8369..8515
/gene="MYO9A"
/standard_name="D15S1267"
/db_xref="UniSTS:68826"
polyA_site 8708
/gene="MYO9A"
ORIGIN
gtgcgcggggtcgggggcgcgcgaccgaagcggataagggacgcggcggcggttggctgtgtctgttgagagagtacaggacagcccggactgcgagaggcggcggcggaggcagtagttgcaccggcagaggcggccgctggcagcggttgaggcggcggtccaacgcgtgctctctgggcggggtgcggcgggggatgtgcctgctcaggccgggcggagtctctctgacagggcgggggatgcgccgcggccgctcgcccggaccctgaggctgctgggcccaccctcccggaaccgtccgaccctcggtggcctcggcctcttctgccatctccggtcctaccctggggcggagggtggaaggcagcttccgtcgaagaggagggggctgcggtggccaccgcggcggagcccgagttattttaccaagaaaatggtttgcacgactttgaacatatactatccatgctgatgggacaggatccaatatgaatataaatgatggaggaagacgacgctttgaagataatgaacatacattacggatatatcctggggctatttcagaagggacaatctactgtccgattcctgccagaaaaaactccacagctgctgaggtgattgagtctcttataaacaaacttcatcttgacaaaacaaaatgttatgttctagcagaggtaaaggaatttggtggagaagaatggattctcaatccaacagattgtccagttcagcgaatgatgctgtggccccgaatggctctggaaaatcgcttaagtggagaggactaccgcttccttctgagagagaaaaaccttgatggatcaatccattatggtagcctgcagtcatggctacgggtaacagaagaacgtcgcaggatgatggaacggggttttcttccacagcctcaacagaaagactttgatgatttatgtagtttacctgatttgaatgagaaaactctcttagaaaacctacgaaatcgctttaagcatgaaaaaatttatacctatgttggcagtattctaatagttattaacccattcaagtttcttcctatttataaccccaaatatgtcaaaatgtatgataaccaccaactgggaaaacttgagccccacatttatgctgtggctgatgtagcttatcatgccatgcttcagcgcaaaaagaatcagtgcatcgtgatttcaggagagagtggttctgggaagactcaaagcacaaactttcttattcaccaccttactgctctcagtcagaaaggatttgccagtggagtagaacagattattcttggagctggaccagtacttgaggcctttggaaatgcaaagacagctcataataacaattcaagtcgttttgggaagtttattcaagtaaattaccaggaaacaggcactgtacttggtgcctatgttgaaaaatatctactggagaagtccagactcgtttatcaggagcataatgaacggaactatcatgtattctattacctcctggcaggagcaagtgaagatgagagatcagcattccatcttaagcaaccagaggaatatcattatctcaatcagataacaaagaaacccctcagacagagctgggatgattattgctatgactctgagccggattgcttcacggtggaaggagaagatttgagacatgactttgagcgcctacaacttgccatggaaatggtaggatttcttcccaagacacgaagacagattttctctcttctctcagccatactacatttgggtaatatctgttacaaaaagaagacataccgggatgactccattgatatctgtaatcctgaagttctgcctattgtctcagaattattagaggttaaagaagagatgctatttgaagcattagttacaaggaagacggtgacagtgggagaaaagcttattttgccatacaagttggcagaggctgtgacagtgaggaactccatggctaagtctctgtatagtgccctgtttgactggatagtttttcgaattaatcatgcacttctgaatagtaaagatttagagcataataccaagacattgtctattggtgttcttgatatttttgggtttgaagattatgaaaataacagctttgaacagttctgtattaattttgctaatgaacgtttacagcactactttaatcagcatatctttaaattggaacaagaggaatatagaactgaaggtatcagctggcacaacatagattacattgataatacctgctgcataaatcttattagcaaaaaaccaacaggactgcttcatcttttggatgaagaaagcaactttccacaggctacaaatcaaacattgctagacaagtttaagcatcaacatgaagataattcttacatcgaatttccagccgtgatggagcctgctttcattataaaacattatgctggaaaagtaaaatatggggtaaaggatttccgggaaaaaaatacagatcatatgcgcccagacattgtagctcttctgagaagcagcaagaatgcatttatctctgggatgattggaattgatcctgtagctgttttccgatgggcaattctccgagcttttttcagagccatggttgctttcagggaagctgggaaaagaaacattcacagaaaaactggacatgatgatacagcgccatgtgcaattttgaaaagtatggatagttttagctttctccaacacccagtccaccagaggagcttagagattctgcagagatgcaaggaagagaagtacagtataacccggaaaaatcccagaacacctctttctgatctccagggcatgaatgctctaaatgaaaaaaaccaacatgatacatttgatattgcctggaatggcagaactgggattcgccagagcagactatcaagtggcacctccttgcttgataaagatggaatatttgctaattcaactagcagcaaactcctggagagagcccatggaattctcacgagaaacaaaaatttcaaatccaagcctgcccttccaaagcacttgctagaagtaaattctttaaagcacctgacaagactgacactacaagatcgcattaccaagtctcttcttcatttacacaagaagaaaaaacctcccagcatcagtgcccagtttcaggcatcattaagcaagctaatggaaacacttggtcaagcagaaccatattttgtaaaatgcattcgctctaatgctgaaaagctgcccttaaggttcagtgatgtcttggtacttagacagcttcgatacaccgggatgctggaaacagttcgaattcgccaatcaggatacagctccaaatattctttccaggattttgtgagccacttccatgtacttcttccccgaaatattattccatccaaatttaacattcaggatttcttcaggaaaataaatcttaatccagataattatcaagttggaaaaaccatggtctttctaaaggagcaggaacgacagcacttacaagatctgcttcaccaagaggtgctccgcagaatcatattgttgcagcgatggttcagggtcttgctgtgtaggcagcatttcctccatctgagacaagcatctgttattatccagagattctggaggaattacctaaatcagaagcaagtcagagatgcagctgtgcagaaggatgcttttgttatggctagtgcagctgctcttctccaagcttcctggcgtgctcacttagagaggcagcggtacttggagttacgggctgcagccatcgttatccagcagaaatggagagattactataggcgcaggcacatggctgctatttgcatacaagcaagatggaaagcctacagggaaagtaaaaggtaccaagaacaaaggaaaaaaattatccttttgcaatcaacatgtagaggattcagagcaagacaaagatttaaagctttaaaagaacaaaggctaagagaaacaaagccagaagttggattggtgaatattaagggatatggatctctggaaattcagggttcagacccttcaggatgggaggattgttcttttgacaacagaataaaagccatagaggaatgtaaatctgtaatagagagtaatcgaattagccgtgaaagttcagtggactgcttgaaggagtcaccaaacaagcagcaggagagagcccaaagccagagtggtgtggacttgcaggaagatgtgcttgtaagagagagacccagatccttggaggatctccatcagaaaaaagtaggccgggctaagagagaaagtaggagaatgagagaactagagcaagctatatttagcttagaattgctgaaagttcgttctcttggtggtatttctccttcagaggatcgcagatggtctacagaattggtgcctgaaggccttcagtctccacggggtacacctgatagtgagagctctcaaggaagcttggaacttctgagctatgaggaaagccaaaagagcaaactagagtctgtcatttcagatgaaggagacttgcagtttccatcacctaagatatccagcagtccaaaatttgattcacgggacaatgccctcagtgcctcaaatgagactagcagtgcagagcatttgaaggatggaactatgaaggaaatggtggtctgcagttctgagtctattacctgtaaaccacagctgaaagactccttcatttcaaatagtctacctacttttttttatatcccccaacaagacccactgaaaacaaattcccaactagacacaagtatccaaagaaacaaactattggaaaatgaagacacagcgggggaagctcttactttggatatcaacagggaaactagaaggtatcactgctcaggaaaagatcagattgttccttctttgaatacagagtcttctaatcctgtgcttaagaagttagaaaagctaaacactgagaaggaagaaaggcaaaaacagttgcagcaacagaatgaaaaagagatgatggaacagattcgccagcaaacagatattttagagaaggagcgcaaagccttcaagacaattgaaaagccaagaattggagagtgtttggtggcaccatcttcctatcagtcaaagcaaagagtagagaggccatcctctctcctcagcttaaatacctcaaataagggagaacttaatgtactggggtccctatcattaaaagatgcagctcttgcccaaaaagacagttcctctgctcacttacccccaaaggaccgacctgtcaccgtgttctttgaaagaaaaggaagtccatgccaatctagtactgtcaaggaattatccaagacagacagaatgggcacccagctgaatgtagcctgtaaactctcaaataatcgcatttcaaaaagagaacactttaggccaactcagtcttacagccacaattctgatgacctttccagagagggaaatgctaggcccattttcttcactccaaaggacaatatgagtattccccttgtcagcaaagaagccttaaacagtaaaaatcctcaactccataaagaagatgaaccagcatggaaacctgtgaagttagctgggccaggccaaagagagacatcacagcgattttcgtcagttgatgaacaagcaaaacttcataagactatgtctcaaggagagattaccaagttggcagtgagacagaaggcttcagattcagatataagacctcagagagctaagatgagattctgggccaaagggaaacaaggggagaagaagactaccagagtgaaacctactacccagtcagaggtttcgccactctttgcaggcacagatgtgattccagctcatcagtttccagatgaattagctgcatatcacccaacacctcctttgagcccagaactgcccggcagttgccggaaggaattcaaagagaacaaagaaccttctccaaaggctaagcgcaagcgaagtgtgaagattagcaacgtggctttggattctatgcattggcaaaatgactctgtccagatcatagcaagtgtcagtgatttaaaaagcatggatgaatttcttctgaaaaaggtgaatgacctagataatgaagacagcaagaaggatacactagtggatgttgtatttaaaaaagccctgaaggaatttcggcagaatatcttcagcttttattcatctgcattggcgatggatgatgggaaaagcatacggtataaagacctctatgcactatttgaacagattctggaaaagacgatgaggcttgagcagcgtgattcactgggtgaatctccagtgagagtttgggtcaacacttttaaagtgtttttagatgaatatatgaatgaattcaagacttcagattgcacagccacaaaggtgccaaaaacagaaagaaagaaaagaaggaaaaaggaaactgatttggtggaagaacacaatggtcacatctttaaagccacccaatatagcatccctacatactgtgaatactgttcttctttgatatggataatggaccgagcctctgtttgcaaattatgcaagtatgcttgccataagaagtgctgtctgaaaaccacagccaagtgctctaaaaagtatgatccagagctgtcatctcgacaatttggggttgaactgtcccgtttgaccagtgaagaccgaactgttcctttagtagtggaaaagctcataaactacattgaaatgcatggactgtatacagaaggtatttatcgaaagtctggttcgactaataaaatcaaggagcttcggcagggtctagatacagatgctgagagtgtaaatctagatgactataacatacacgtcattgcaagtgtattcaaacaatggcttcgagatttgcccaatcctctcatgacctttgaactctatgaggaatttcttcgagctatgggccttcaggagaggaaggagacaatccgtggtgtatactctgtgattgatcaactctcccgaactcatctcaatacactggaacgcctcatctttcatctagtcaggattgctctgcaggaagacactaatcgaatgtctgctaatgctttggccattgtgtttgcgccctgcattctccgctgccctgacaccactgacccactacaaagtgtacaggacatcagtaagactaccacttgtgtggaactgattgttgtggaacaaatgaataaatacaaggctcgtctcaaagatatcagtagcttggaatttgctgagaataaggcaaagaccaggttgtcactgattcgtagatcaatgggaaaggggcgtattcgtcgaggaaactatccaggtccatcgtctcctgttgtagttcggttgccttctgtgtctgatgtctcagaggagaccttgactagtgaggcagccatggagactgacatcacagaacagcagcaagcagctatgcagcaggaggagagagtactgactgagcagattgagaacctacagaaggagaaggaggagctaacatttgagatgcttgtactggaaccccgtgcctctgatgatgaaacccttgagtctgaggcctccattgggactgctgatagctcagagaatttgaatatggagtctgaatatgctatctctgagaaatcagaaagaagcttagcccttagctccctgaagacagctggcaagtctgaaccttccagcaagttgcgaaagcaacttaaaaagcagcaagactctttagatgtcgtggactcttcggtctcctctttatgtctgtctaacacggcatcatctcatgggaccagaaaactatttcagatttattccaaatctccattctaccgagctgcctcaggtaatgaggccctgggaatggaaggaccattgggccagaccaaattcctggaagacaagcctcagttcatcagcagaggaaccttcaacccggaaaagggcaaacaaaaattaaagaatgtgaaaaactcacctcagaaaaccaaagagaccccagaggggacagtcatgtctggccgcagaaaaactgtggacccagactgcacctccaaccaacagctagcactctttggaaataatgaatttatggtctgaaccggcagatgtgtgtccctccgtggctacagagtggtaaacaaatctcacctttggggctgcgtttcatcacctcgtccacaatagtcaatcctaattgtggtcctgcctcttttctaagcatatggctaagactgtatgtgctgaattcctgggcctcctgcagaagcagaaagcctgctggggatggtgccagctgtgccttggctgttgtatttgaattgagatttttactatacaaagccacctagggcctggggatttgggtcagttgtagttgcctctcccccaccctcttttcccttcccaaaggtgggtgttgaactaggggggatattgctgtcctgagggaccctctcatttctgacatttgaagaaaacgtataaatctttcttaaccgtgaaagcaaaagcctttgggtttattttgggatagttaggagctagggtagaatataatttttttccaaaaacttacttacaaacaaaaagcctaatccctctattttaagatttctgaaaaaacactccatgttatattctggggaaagcaaaaacaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:4649 -> Molecular function: GO:0003774 [motor activity] evidence: IEA
GeneID:4649 -> Molecular function: GO:0003779 [actin binding] evidence: IEA
GeneID:4649 -> Molecular function: GO:0005096 [GTPase activator activity] evidence: IEA
GeneID:4649 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:4649 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:4649 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:4649 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: TAS
GeneID:4649 -> Biological process: GO:0007601 [visual perception] evidence: TAS
GeneID:4649 -> Biological process: GO:0051056 [regulation of small GTPase mediated signal transduction] evidence: TAS
GeneID:4649 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:4649 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:4649 -> Cellular component: GO:0016461 [unconventional myosin complex] evidence: NAS
by
@meso_cacase at
DBCLS
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