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2024-03-29 21:07:19, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_006461               3824 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens sperm associated antigen 5 (SPAG5), mRNA.
ACCESSION   NM_006461
VERSION     NM_006461.3  GI:73623034
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3824)
  AUTHORS   Olson,J.E., Wang,X., Pankratz,V.S., Fredericksen,Z.S., Vachon,C.M.,
            Vierkant,R.A., Cerhan,J.R. and Couch,F.J.
  TITLE     Centrosome-related genes, genetic variation, and risk of breast
            cancer
  JOURNAL   Breast Cancer Res. Treat. 125 (1), 221-228 (2011)
   PUBMED   20508983
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 3824)
  AUTHORS   Manning,A.L., Bakhoum,S.F., Maffini,S., Correia-Melo,C., Maiato,H.
            and Compton,D.A.
  TITLE     CLASP1, astrin and Kif2b form a molecular switch that regulates
            kinetochore-microtubule dynamics to promote mitotic progression and
            fidelity
  JOURNAL   EMBO J. 29 (20), 3531-3543 (2010)
   PUBMED   20852589
  REMARK    GeneRIF: Data show that CLASP1-astrin-Kif2b complex acts as a
            central switch at kinetochores that defines mitotic progression and
            promotes fidelity by temporally regulating kinetochore-microtuble
            attachments.
REFERENCE   3  (bases 1 to 3824)
  AUTHORS   Liu,L., Akhter,S., Bae,J.B., Mukhopadhyay,S.S., Richie,C.T., Liu,X.
            and Legerski,R.
  TITLE     SNM1B/Apollo interacts with astrin and is required for the prophase
            cell cycle checkpoint
  JOURNAL   Cell Cycle 8 (4), 628-638 (2009)
   PUBMED   19197158
  REMARK    GeneRIF: Results suggest that SNM1B/Apollo and Astrin function
            together to enforce the prophase checkpoint in response to spindle
            stress.
REFERENCE   4  (bases 1 to 3824)
  AUTHORS   Du,J., Jablonski,S., Yen,T.J. and Hannon,G.J.
  TITLE     Astrin regulates Aurora-A localization
  JOURNAL   Biochem. Biophys. Res. Commun. 370 (2), 213-219 (2008)
   PUBMED   18361916
  REMARK    GeneRIF: Astrin acts upstream of Aurora-A to regulate its mitotic
            spindle localization.
REFERENCE   5  (bases 1 to 3824)
  AUTHORS   Cheng,T.S., Hsiao,Y.L., Lin,C.C., Yu,C.T., Hsu,C.M., Chang,M.S.,
            Lee,C.I., Huang,C.Y., Howng,S.L. and Hong,Y.R.
  TITLE     Glycogen synthase kinase 3beta interacts with and phosphorylates
            the spindle-associated protein astrin
  JOURNAL   J. Biol. Chem. 283 (4), 2454-2464 (2008)
   PUBMED   18055457
  REMARK    GeneRIF: GSK3beta interacts with and phosphorylates the
            spindle-associated protein Astrin, resulting in targeting Astrin to
            the spindle microtubules and kinetochores.
REFERENCE   6  (bases 1 to 3824)
  AUTHORS   Yang,Y.C., Hsu,Y.T., Wu,C.C., Chen,H.T. and Chang,M.S.
  TITLE     Silencing of astrin induces the p53-dependent apoptosis by
            suppression of HPV18 E6 expression and sensitizes cells to
            paclitaxel treatment in HeLa cells
  JOURNAL   Biochem. Biophys. Res. Commun. 343 (2), 428-434 (2006)
   PUBMED   16546135
  REMARK    GeneRIF: These findings suggest that the silencing of astrin induce
            a p53-dependent apoptosis and has an additive effect on paclitaxel
            treatment.
REFERENCE   7  (bases 1 to 3824)
  AUTHORS   Le,X.F., Lammayot,A., Gold,D., Lu,Y., Mao,W., Chang,T., Patel,A.,
            Mills,G.B. and Bast,R.C. Jr.
  TITLE     Genes affecting the cell cycle, growth, maintenance, and drug
            sensitivity are preferentially regulated by anti-HER2 antibody
            through phosphatidylinositol 3-kinase-AKT signaling
  JOURNAL   J. Biol. Chem. 280 (3), 2092-2104 (2005)
   PUBMED   15504738
REFERENCE   8  (bases 1 to 3824)
  AUTHORS   Gruber,J., Harborth,J., Schnabel,J., Weber,K. and Hatzfeld,M.
  TITLE     The mitotic-spindle-associated protein astrin is essential for
            progression through mitosis
  JOURNAL   J. Cell. Sci. 115 (PT 21), 4053-4059 (2002)
   PUBMED   12356910
REFERENCE   9  (bases 1 to 3824)
  AUTHORS   Mack,G.J. and Compton,D.A.
  TITLE     Analysis of mitotic microtubule-associated proteins using mass
            spectrometry identifies astrin, a spindle-associated protein
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 98 (25), 14434-14439 (2001)
   PUBMED   11724960
REFERENCE   10 (bases 1 to 3824)
  AUTHORS   Chang,M.S., Huang,C.J., Chen,M.L., Chen,S.T., Fan,C.C., Chu,J.M.,
            Lin,W.C. and Yang,Y.C.
  TITLE     Cloning and characterization of hMAP126, a new member of mitotic
            spindle-associated proteins
  JOURNAL   Biochem. Biophys. Res. Commun. 287 (1), 116-121 (2001)
   PUBMED   11549262
  REMARK    GeneRIF: hMap126 is abundantly expressed in testis and localized in
            mitotic spindle and may be involved in the functional and dynamic
            regulation of mitotic spindles.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BI459711.1, BC000322.2 and
            BQ773438.1.
            On Aug 19, 2005 this sequence version replaced gi:46399193.
            
            Summary: This gene encodes a protein associated with the mitotic
            spindle apparatus. The encoded protein may be involved in the
            functional and dynamic regulation of mitotic spindles. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF063308.1, AF399910.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-300               BI459711.1         4-303
            301-3797            BC000322.2         261-3757
            3798-3824           BQ773438.1         1-27                c
FEATURES             Location/Qualifiers
     source          1..3824
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q11.2"
     gene            1..3824
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /note="sperm associated antigen 5"
                     /db_xref="GeneID:10615"
                     /db_xref="HGNC:13452"
     exon            1..143
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    36..38
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /note="upstream in-frame stop codon"
     CDS             93..3674
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /note="mitotic spindle coiled-coil related protein;
                     astrin; mitotic spindle associated protein p126; mitotic
                     spindle-associated protein p126"
                     /codon_start=1
                     /product="sperm-associated antigen 5"
                     /protein_id="NP_006452.3"
                     /db_xref="GI:73623035"
                     /db_xref="CCDS:CCDS32594.1"
                     /db_xref="GeneID:10615"
                     /db_xref="HGNC:13452"
                     /translation="
MWRVKKLSLSLSPSPQTGKPSMRTPLRELTLQPGALTNSGKRSPACSSLTPSLCKLGLQEGSNNSSPVDFVNNKRTDLSSEHFSHSSKWLETCQHESDEQPLDPIPQISSTPKTSEEAVDPLGNYMVKTIVLVPSPLGQQQDMIFEARLDTMAETNSISLNGPLRTDDLVREEVAPCMGDRFSEVAAVSEKPIFQESPSHLLEESPPNPCSEQLHCSKESLSSRTEAVREDLVPSESNAFLPSSVLWLSPSTALAADFRVNHVDPEEEIVEHGAMEEREMRFPTHPKESETEDQALVSSVEDILSTCLTPNLVEMESQEAPGPAVEDVGRILGSDTESWMSPLAWLEKGVNTSVMLENLRQSLSLPSMLRDAAIGTTPFSTCSVGTWFTPSAPQEKSTNTSQTGLVGTKHSTSETEQLLCGRPPDLTALSRHDLEDNLLSSLVILEVLSRQLRDWKSQLAVPHPETQDSSTQTDTSHSGITNKLQHLKESHEMGQALQQARNVMQSWVLISKELISLLHLSLLHLEEDKTTVSQESRRAETLVCCCFDLLKKLRAKLQSLKAEREEARHREEMALRGKDAAEIVLEAFCAHASQRISQLEQDLASMREFRGLLKDAQTQLVGLHAKQEELVQQTVSLTSTLQQDWRSMQLDYTTWTALLSRSRQLTEKLTVKSQQALQERDVAIEEKQEVSRVLEQVSAQLEECKGQTEQLELENSRLATDLRAQLQILANMDSQLKELQSQHTHCAQDLAMKDELLCQLTQSNEEQAAQWQKEEMALKHMQAELQQQQAVLAKEVRDLKETLEFADQENQVAHLELGQVECQLKTTLEVLRERSLQCENLKDTVENLTAKLASTIADNQEQDLEKTRQYSQKLGLLTEQLQSLTLFLQTKLKEKTEQETLLLSTACPPTQEHPLPNDRTFLGSILTAVADEEPESTPVPLLGSDKSAFTRVASMVSLQPAETPGMEESLAEMSIMTTELQSLCSLLQESKEEAIRTLQRKICELQARLQAQEEQHQEVQKAKEADIEKLNQALCLRYKNEKELQEVIQQQNEKILEQIDKSGELISLREEVTHLTRSLRRAETETKVLQEALAGQLDSNCQPMATNWIQEKVWLSQEVDKLRVMFLEMKNEKEKLMIKFQSHRNILEENLRRSDKELEKLDDIVQHIYKTLLSIPEVVRGCKELQGLLEFLS
"
     misc_feature    219..221
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96R06.2); phosphorylation site"
     misc_feature    276..278
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96R06.2); phosphorylation site"
     misc_feature    276..278
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    288..290
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96R06.2); phosphorylation site"
     misc_feature    288..290
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    423..425
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    495..497
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96R06.2); phosphorylation site"
     misc_feature    495..497
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    837..839
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1092..1094
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96R06.2); phosphorylation site"
     misc_feature    1092..1094
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1098..1100
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (Q96R06.2); phosphorylation site"
     misc_feature    1113..1115
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96R06.2); phosphorylation site"
     misc_feature    1113..1115
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1149..1151
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1176..1178
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96R06.2); phosphorylation site"
     misc_feature    1176..1178
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1182..1184
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1221..1223
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1257..1259
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1281..1283
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1284..1286
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1293..1295
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1536..2642
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96R06.2);
                     Region: Interaction with KNSTRN"
     misc_feature    <1869..>2678
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /note="chromosome segregation protein SMC, common
                     bacterial type; Region: SMC_prok_B; TIGR02168"
                     /db_xref="CDD:162739"
     misc_feature    2901..2903
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     exon            144..269
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     variation       165
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11540040"
     exon            270..1354
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     STS             734..976
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /standard_name="RH79796"
                     /db_xref="UniSTS:89253"
     exon            1355..1529
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            1530..1604
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            1605..1697
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            1698..1832
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            1833..1952
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            1953..2045
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            2046..2159
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     STS             2153..3447
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /standard_name="D1S3690"
                     /db_xref="UniSTS:474268"
     exon            2160..2253
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            2254..2401
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            2402..2504
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            2505..2638
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     variation       2519
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11540041"
     exon            2639..2777
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            2778..2889
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            2890..2976
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            2977..3097
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            3098..3209
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            3210..3290
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            3291..3446
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            3447..3521
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     STS             3499..3669
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /standard_name="RH102973"
                     /db_xref="UniSTS:97307"
     exon            3522..3602
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     exon            3603..3808
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /inference="alignment:Splign:1.39.8"
     STS             3653..3780
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /standard_name="G21480"
                     /db_xref="UniSTS:76245"
     polyA_signal    3780..3785
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
     polyA_site      3799
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
                     /experiment="experimental evidence, no additional details
                     recorded"
     polyA_site      3808
                     /gene="SPAG5"
                     /gene_synonym="DEEPEST; hMAP126; MAP126"
ORIGIN      
ggaagcgcagagcaggttcaaacacagacggcgggtgaacatggcgtcctcgacttggtctgagacgtgataggcctgccttctggttgaagatgtggcgagtgaaaaaactgagcctcagcctgtcgccttcgccccagacgggaaaaccatctatgagaactcctctccgtgaacttaccctgcagcccggtgccctcaccaactctggaaaaagatcccccgcttgctcctcgctgaccccatcactgtgcaagctggggctgcaggaaggcagcaacaactcatctccagtggattttgtaaataacaagaggacagacttatcttcagaacatttcagtcattcctcaaagtggctagaaacttgtcagcatgaatcagatgagcagcctctagatccaattccccaaattagctctactcctaaaacgtctgaggaagcagtagacccactgggcaattatatggttaaaaccatcgtccttgtaccatctccactggggcagcaacaagacatgatatttgaggcccgtttagataccatggcagagacaaacagcatatctttaaatggacctttgagaacagacgatctggtgagagaggaggtggcaccctgcatgggagacaggttttcagaagttgctgctgtatctgagaaacctatctttcaggaatctccgtcccatctcttagaggagtctccaccaaatccctgttctgaacaactacattgctccaaggaaagcctgagcagtagaactgaggctgtgcgtgaggacttagtaccttctgaaagtaacgccttcttgccttcctctgttctctggctttccccttcaactgccttggcagcagatttccgtgtcaatcatgtggacccagaggaggaaattgtagagcatggagctatggaggaaagagaaatgaggtttcccacacatcctaaggagtctgaaacagaagatcaagcacttgtctcaagtgtggaagatattctgtccacatgcctgacaccaaatctagtagaaatggaatcccaagaagctccaggcccagcagtagaagatgttggtaggattcttggctctgatacagagtcttggatgtccccactggcctggctggaaaaaggtgtaaatacctccgtcatgctggaaaatctccgccaaagcttatcccttccctcgatgcttcgggatgctgcaattggcactacccctttctctacttgctcggtggggacttggtttactccttcagcaccacaggaaaagagtacaaacacatcccagacaggcctggttggcaccaagcacagtacttctgagacagagcagctcctgtgtggccggcctccagatctgactgccttgtctcgacatgacttggaagataacctgctgagctctcttgtcattctggaggttctctcccgccagcttcgggactggaagagccagctggctgtccctcacccagaaacccaggacagtagcacacagactgacacatctcacagtgggataactaataaacttcagcatcttaaggagagccatgagatgggacaggccctacagcaggccagaaatgtcatgcaatcatgggtgcttatctctaaagagctgatatccttgcttcacctatccctgttgcatttagaagaagataagactactgtgagtcaggagtctcggcgtgcagaaacattggtctgttgctgttttgatttgctgaagaaattgagggcaaagctccagagcctcaaagcagaaagggaggaggcaaggcacagagaggaaatggctctcagaggcaaggatgcggcagagatagtgttggaggctttctgtgcacacgccagccagcgcatcagccagctggaacaggacctagcatccatgcgggaattcagaggccttctgaaggatgcccagacccaactggtagggcttcatgccaagcaagaagagctggttcagcagacagtgagtcttacttctaccttgcaacaagactggaggtccatgcaactggattatacaacatggacagctttgctgagtcggtcccgacaactcacagagaaactcacagtcaagagccagcaagccctgcaggaacgtgatgtggcaattgaggaaaagcaggaggtttctagggtgctggaacaagtctctgcccagttagaggagtgcaaaggccaaacagaacaactggagttggaaaacagtcgtctagcaacagatctccgggctcagttgcagattctggccaacatggacagccagctaaaagagctacagagtcagcatacccattgtgcccaggacctggctatgaaggatgagttactctgccagcttacccagagcaatgaggagcaggctgctcaatggcaaaaggaagagatggcactaaaacacatgcaggcagaactgcagcagcaacaagctgtcctggccaaagaggtgcgggacctgaaagagaccttggagtttgcagaccaggagaatcaggttgctcacctggagctgggtcaggttgagtgtcaattgaaaaccacactggaagtgctccgggagcgcagcttgcagtgtgagaacctcaaggacactgtagagaacctaacggctaaactggccagcaccatagcagataaccaggagcaagatctggagaaaacacggcagtactctcaaaagctagggctgctgactgagcaactacagagcctgactctctttctacagacaaaactaaaggagaagactgaacaagagacccttctgctgagtacagcctgtcctcccacccaggaacaccctctgcctaatgacaggaccttcctgggaagcatcttgacagcagtggcagatgaagagccagaatcaactcctgtgcccttgcttggaagtgacaagagtgctttcacccgagtagcatcaatggtttcccttcagcccgcagagaccccaggcatggaggagagcctggcagaaatgagtattatgactactgagcttcagagtctttgttccctgctacaagagtctaaagaagaagccatcaggactctgcagcgaaaaatttgtgagctgcaagctaggctgcaggcccaggaagaacagcatcaggaagtccagaaggcaaaagaagcagacatagagaagctgaaccaggccttgtgcttgcgctacaagaatgaaaaggagctccaggaagtgatacagcagcagaatgagaagatcctagaacagatagacaagagtggcgagctcataagccttagagaggaggtgacccaccttacccgctcacttcggcgtgcggagacagagaccaaagtgctccaggaggccctggcaggccagctggactccaactgccagcctatggccaccaattggatccaggagaaagtgtggctctctcaggaggtggacaaactgagagtgatgttcctggagatgaaaaatgagaaggaaaaactcatgatcaagttccagagccatagaaatatcctagaggagaaccttcggcgctctgacaaggagttagaaaaactagatgacattgttcagcatatttataagaccctgctctctattccagaggtggtgaggggatgcaaagaactacagggattgctggaatttctgagctaagaaactgaaagccagaatctgcttcacctctttttacctgcaatacccccttaccccaataccaagaccaactggcatagagccaactgagataaatgctatttaaataaagtgtatttaatgaatttctccaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:10615 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:10615 -> Biological process: GO:0000070 [mitotic sister chromatid segregation] evidence: IMP
            GeneID:10615 -> Biological process: GO:0000090 [mitotic anaphase] evidence: IMP
            GeneID:10615 -> Biological process: GO:0007049 [cell cycle] evidence: NAS
            GeneID:10615 -> Biological process: GO:0007051 [spindle organization] evidence: IMP
            GeneID:10615 -> Biological process: GO:0007051 [spindle organization] evidence: NAS
            GeneID:10615 -> Biological process: GO:0007059 [chromosome segregation] evidence: IMP
            GeneID:10615 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: NAS
            GeneID:10615 -> Biological process: GO:0051301 [cell division] evidence: IEA
            GeneID:10615 -> Biological process: GO:0051988 [regulation of attachment of spindle microtubules to kinetochore] evidence: IMP
            GeneID:10615 -> Cellular component: GO:0000776 [kinetochore] evidence: IDA
            GeneID:10615 -> Cellular component: GO:0000777 [condensed chromosome kinetochore] evidence: IEA
            GeneID:10615 -> Cellular component: GO:0000922 [spindle pole] evidence: IEA
            GeneID:10615 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:10615 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:10615 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:10615 -> Cellular component: GO:0005876 [spindle microtubule] evidence: IEA
            GeneID:10615 -> Cellular component: GO:0035371 [microtubule plus end] evidence: IDA
            GeneID:10615 -> Cellular component: GO:0072686 [mitotic spindle] evidence: IDA

by @meso_cacase at DBCLS
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