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2024-03-29 14:57:06, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_006446               2800 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens solute carrier organic anion transporter family,
            member 1B1 (SLCO1B1), mRNA.
ACCESSION   NM_006446
VERSION     NM_006446.4  GI:225543524
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2800)
  AUTHORS   Zhou,Q., Chen,Q.X., Ruan,Z.R., Yuan,H., Xu,H.M. and Zeng,S.
  TITLE     CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and
            gender are determinants of inter-subject variability in
            pitavastatin pharmacokinetics
  JOURNAL   Pharmazie 68 (3), 187-194 (2013)
   PUBMED   23556337
  REMARK    GeneRIF: Compared to non-SLCO1B1*17 carriers, SLCO1B1*17 carriers
            had higher peak plasma concentration and AUC of the acid and
            lactone forms of pivastatin
REFERENCE   2  (bases 1 to 2800)
  AUTHORS   Ulvestad,M., Skottheim,I.B., Jakobsen,G.S., Bremer,S., Molden,E.,
            Asberg,A., Hjelmesaeth,J., Andersson,T.B., Sandbu,R. and
            Christensen,H.
  TITLE     Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and
            intestine on interpatient pharmacokinetic variability of
            atorvastatin in obese subjects
  JOURNAL   Clin. Pharmacol. Ther. 93 (3), 275-282 (2013)
   PUBMED   23361102
  REMARK    GeneRIF: OATP1B1 phenotype is more important than CYP3A4 and MDR1
            phenotypes for the individual pharmacokinetic variability of
            atorvastatin.
REFERENCE   3  (bases 1 to 2800)
  AUTHORS   Yao,J., Hong,W., Huang,J., Zhan,K., Huang,H. and Hong,M.
  TITLE     N-Glycosylation dictates proper processing of organic anion
            transporting polypeptide 1B1
  JOURNAL   PLoS ONE 7 (12), E52563 (2012)
   PUBMED   23285087
  REMARK    GeneRIF: Asparagine residues that are possibly involved in
            N-glycosylation were substituted with glutamine residues and
            identified three glycosylation sites (Asn134, Asn503 and Asn516)
            within the structure of OATP1B1.
REFERENCE   4  (bases 1 to 2800)
  AUTHORS   Jung,D., Hagenbuch,B., Gresh,L., Pontoglio,M., Meier,P.J. and
            Kullak-Ublick,G.A.
  TITLE     Characterization of the human OATP-C (SLC21A6) gene promoter and
            regulation of liver-specific OATP genes by hepatocyte nuclear
            factor 1 alpha
  JOURNAL   J. Biol. Chem. 276 (40), 37206-37214 (2001)
   PUBMED   11483603
  REMARK    GeneRIF: The promoter of SLC21A6 gene was characterized and
            regulated by HNF 1alpha.
REFERENCE   5  (bases 1 to 2800)
  AUTHORS   Cui,Y., Konig,J., Leier,I., Buchholz,U. and Keppler,D.
  TITLE     Hepatic uptake of bilirubin and its conjugates by the human organic
            anion transporter SLC21A6
  JOURNAL   J. Biol. Chem. 276 (13), 9626-9630 (2001)
   PUBMED   11134001
REFERENCE   6  (bases 1 to 2800)
  AUTHORS   Konig,J., Cui,Y., Nies,A.T. and Keppler,D.
  TITLE     Localization and genomic organization of a new hepatocellular
            organic anion transporting polypeptide
  JOURNAL   J. Biol. Chem. 275 (30), 23161-23168 (2000)
   PUBMED   10779507
REFERENCE   7  (bases 1 to 2800)
  AUTHORS   Tamai,I., Nezu,J., Uchino,H., Sai,Y., Oku,A., Shimane,M. and
            Tsuji,A.
  TITLE     Molecular identification and characterization of novel members of
            the human organic anion transporter (OATP) family
  JOURNAL   Biochem. Biophys. Res. Commun. 273 (1), 251-260 (2000)
   PUBMED   10873595
REFERENCE   8  (bases 1 to 2800)
  AUTHORS   Konig,J., Cui,Y., Nies,A.T. and Keppler,D.
  TITLE     A novel human organic anion transporting polypeptide localized to
            the basolateral hepatocyte membrane
  JOURNAL   Am. J. Physiol. Gastrointest. Liver Physiol. 278 (1), G156-G164
            (2000)
   PUBMED   10644574
REFERENCE   9  (bases 1 to 2800)
  AUTHORS   Hsiang,B., Zhu,Y., Wang,Z., Wu,Y., Sasseville,V., Yang,W.P. and
            Kirchgessner,T.G.
  TITLE     A novel human hepatic organic anion transporting polypeptide
            (OATP2). Identification of a liver-specific human organic anion
            transporting polypeptide and identification of rat and human
            hydroxymethylglutaryl-CoA reductase inhibitor transporters
  JOURNAL   J. Biol. Chem. 274 (52), 37161-37168 (1999)
   PUBMED   10601278
REFERENCE   10 (bases 1 to 2800)
  AUTHORS   Abe,T., Kakyo,M., Tokui,T., Nakagomi,R., Nishio,T., Nakai,D.,
            Nomura,H., Unno,M., Suzuki,M., Naitoh,T., Matsuno,S. and Yawo,H.
  TITLE     Identification of a novel gene family encoding human liver-specific
            organic anion transporter LST-1
  JOURNAL   J. Biol. Chem. 274 (24), 17159-17163 (1999)
   PUBMED   10358072
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC020696.1, AF205071.1 and
            AC022335.8.
            This sequence is a reference standard in the RefSeqGene project.
            On Mar 21, 2009 this sequence version replaced gi:141801825.
            
            Summary: This gene encodes a liver-specific member of the organic
            anion transporter family. The encoded protein is a transmembrane
            receptor that mediates the sodium-independent uptake of numerous
            endogenous compounds including bilirubin, 17-beta-glucuronosyl
            estradiol and leukotriene C4. This protein is also involved in the
            removal of drug compounds such as statins, bromosulfophthalein and
            rifampin from the blood into the hepatocytes. Polymorphisms in the
            gene encoding this protein are associated with impaired transporter
            function. [provided by RefSeq, Mar 2009].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF205071.1, AB026257.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BC020696.1         2-9
            9-491               AF205071.1         39-521
            492-492             AC022335.8         82644-82644         c
            493-2800            AF205071.1         523-2830
FEATURES             Location/Qualifiers
     source          1..2800
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p"
     gene            1..2800
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /note="solute carrier organic anion transporter family,
                     member 1B1"
                     /db_xref="GeneID:10599"
                     /db_xref="HGNC:10959"
                     /db_xref="MIM:604843"
     exon            1..43
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    1
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /note="transcription start site"
     exon            44..188
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    45..47
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /note="upstream in-frame stop codon"
     variation       80
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373658115"
     variation       91
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201251518"
     variation       102
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:180888034"
     CDS             105..2180
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /note="solute carrier family 21 (organic anion
                     transporter), member 6; sodium-independent organic
                     anion-transporting polypeptide 2; liver-specific organic
                     anion transporter 1; OATP-2; solute carrier family 21
                     member 6"
                     /codon_start=1
                     /product="solute carrier organic anion transporter family
                     member 1B1"
                     /protein_id="NP_006437.3"
                     /db_xref="GI:225543525"
                     /db_xref="CCDS:CCDS8685.1"
                     /db_xref="GeneID:10599"
                     /db_xref="HGNC:10959"
                     /db_xref="MIM:604843"
                     /translation="
MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETHC
"
     misc_feature    183..1970
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /note="Organic Anion Transporter Polypeptide (OATP)
                     family; Region: OATP; pfam03137"
                     /db_xref="CDD:202550"
     misc_feature    189..248
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    306..368
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    387..461
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    <600..>806
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /note="The Major Facilitator Superfamily (MFS) is a large
                     and diverse group of secondary transporters that includes
                     uniporters, symporters, and antiporters. MFS proteins
                     facilitate the transport across cytoplasmic or internal
                     membranes of a variety of...; Region: MFS; cd06174"
                     /db_xref="CDD:119392"
     misc_feature    609..695
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    753..815
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    870..944
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    1098..1163
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    1224..1295
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    1308..1379
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    1467..1628
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /note="The kazal-type serine protease inhibitor domain has
                     been detected in an extracellular loop region of solute
                     carrier 21 (SLC21) family members (organic anion
                     transporters) , which may regulate the specificity of
                     anion uptake. The KAZAL_SLC21 domain is a...; Region:
                     KAZAL_SLC21; cd01330"
                     /db_xref="CDD:29001"
     misc_feature    1716..1784
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    1812..1889
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     misc_feature    1992..2045
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9Y6L6.2);
                     transmembrane region"
     variation       105
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:185905373"
     variation       132
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11557087"
     variation       134
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113635866"
     variation       159
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:376829525"
     variation       170
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142087529"
     variation       183
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190581845"
     exon            189..330
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       189
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146317972"
     variation       220
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370556411"
     variation       273
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139257324"
     variation       274
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61760182"
     variation       288
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144164853"
     variation       314
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148697674"
     variation       315
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373327528"
     variation       321
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:56101265"
     exon            331..463
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       339
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370130036"
     variation       349
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:56061388"
     variation       359
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71581978"
     variation       402
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144508550"
     variation       421
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200227560"
     exon            464..585
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       492
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2306283"
     variation       505
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:202074496"
     variation       514
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151204465"
     variation       515
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11045818"
     variation       523
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147450830"
     variation       527
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368095348"
     variation       556
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2306282"
     variation       559
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145144129"
     variation       567
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11045819"
     variation       571
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:72559745"
     variation       578
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140730264"
     exon            586..732
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       589
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138374684"
     variation       622
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141467543"
     variation       625
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4149056"
     variation       639
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371375183"
     variation       645
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138965366"
     variation       646
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142101690"
     variation       663
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200331427"
     variation       675
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4149057"
     variation       681
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376996580"
     variation       682
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:72559746"
     variation       695
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148105486"
     variation       697
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376755211"
     variation       701
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2291075"
     variation       703
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150623527"
     variation       710
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369764409"
     variation       712
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4603354"
     exon            733..831
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       735
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:184348772"
     variation       737
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201722521"
     variation       742
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372477451"
     variation       765
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377502108"
     variation       766
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:139691245"
     variation       768
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79135870"
     variation       778
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370943869"
     variation       799
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374328647"
     variation       807
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147421160"
     variation       817
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374113543"
     exon            832..1074
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       837
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11045852"
     variation       861
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183501729"
     variation       862
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11045853"
     variation       912
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201438350"
     variation       926
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192911820"
     variation       938
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:182303784"
     variation       944..945
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:72559742"
     variation       944
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:199712476"
     variation       958
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148647456"
     variation       986
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11045854"
     variation       1002
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139907543"
     variation       1048
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373619379"
     variation       1068
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201363750"
     exon            1075..1239
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       1085
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:151155254"
     variation       1104
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:77871475"
     variation       1111
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:72559747"
     variation       1116..1117
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace=""
                     /replace="gt"
                     /db_xref="dbSNP:113495867"
     variation       1138
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61760243"
     variation       1139
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145167231"
     variation       1147
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146867151"
     variation       1162
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:55901008"
     variation       1180
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147750118"
     variation       1184
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140674443"
     variation       1190
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:57040246"
     variation       1211
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377208842"
     exon            1240..1435
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       1281
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373127202"
     variation       1290
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200621156"
     variation       1304
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:59113707"
     variation       1317
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376060151"
     variation       1330
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199859384"
     variation       1350
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:77468276"
     variation       1352
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11045859"
     variation       1376
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:61176925"
     variation       1393
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143266211"
     variation       1398
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:56387224"
     variation       1412
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139049237"
     variation       1413
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142965323"
     variation       1423
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139797371"
     variation       1426
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:141779296"
     variation       1431
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:150573622"
     exon            1436..1601
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       1489
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:72559748"
     variation       1511
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374859808"
     variation       1556
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:74064211"
     variation       1560
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:202110446"
     variation       1567
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:59502379"
     variation       1569
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:144733213"
     variation       1582
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145491008"
     variation       1599
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74064213"
     exon            1602..1786
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       1612
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368423244"
     variation       1636
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200319276"
     variation       1668
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:112909948"
     variation       1677
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71581987"
     variation       1693
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184762532"
     variation       1726
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:71581988"
     variation       1732
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:72661137"
     variation       1745
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200158405"
     variation       1755
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375465421"
     exon            1787..1851
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       1796
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:146415464"
     variation       1819
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201987253"
     variation       1820
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373681186"
     variation       1828
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:74700754"
     variation       1833
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371102023"
     variation       1836
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201001269"
     variation       1842
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71581941"
     exon            1852..1969
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       1884
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199945870"
     variation       1888
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139026094"
     variation       1897
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201861991"
     variation       1898
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201556175"
     variation       1913
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143812591"
     variation       1940
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370991447"
     variation       1941
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377350683"
     variation       1969
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368052440"
     exon            1970..2787
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /inference="alignment:Splign:1.39.8"
     variation       1981
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:183624077"
     variation       1982
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200526972"
     variation       2014
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:112560299"
     variation       2033
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:34671512"
     variation       2068
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:56199088"
     variation       2082
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368443740"
     variation       2104
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:55737008"
     variation       2136
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200995543"
     variation       2142
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375293385"
     variation       2144
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200467000"
     variation       2149
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140790673"
     variation       2161
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201158567"
     variation       2166
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367879427"
     variation       2199
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:113870212"
     STS             2203..2306
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /standard_name="RH1600"
                     /db_xref="UniSTS:10796"
     variation       2220
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:79775553"
     variation       2226
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:71581985"
     variation       2238
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113192433"
     variation       2262
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:72655363"
     variation       2301
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:74064260"
     variation       2347
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4149085"
     variation       2389
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201787919"
     variation       2508
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4149086"
     variation       2585
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112204127"
     variation       2619
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:4149087"
     variation       2629
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11045891"
     variation       2643
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4149088"
     variation       2661
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71581986"
     variation       2681
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:372380851"
     variation       2755
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61760249"
     polyA_signal    2763..2768
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
     variation       2785
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:141979092"
     polyA_site      2787
                     /gene="SLCO1B1"
                     /gene_synonym="HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2;
                     OATPC; SLC21A6"
ORIGIN      
aaagggtggacttgttgcagttgctgtaggattctaaatccaggtgattgtttcaaactgagcatcaacaacaaaaacatttgtatgatatctatatttcaatcatggaccaaaatcaacatttgaataaaacagcagaggcacaaccttcagagaataagaaaacaagatactgcaatggattgaagatgttcttggcagctctgtcactcagctttattgctaagacactaggtgcaattattatgaaaagttccatcattcatatagaacggagatttgagatatcctcttctcttgttggttttattgacggaagctttgaaattggaaatttgcttgtgattgtatttgtgagttactttggatccaaactacatagaccaaagttaattggaatcggttgtttcattatgggaattggaggtgttttgactgctttgccacatttcttcatgggatattacaggtattctaaagaaactaatatcaattcatcagaaaattcaacatcgaccttatccacttgtttaattaatcaaattttatcactcaatagagcatcacctgagatagtgggaaaaggttgtttaaaggaatctgggtcatacatgtggatatatgtgttcatgggtaatatgcttcgtggaataggggagactcccatagtaccattggggctttcttacattgatgatttcgctaaagaaggacattcttctttgtatttaggtatattgaatgcaatagcaatgattggtccaatcattggctttaccctgggatctctgttttctaaaatgtacgtggatattggatatgtagatctaagcactatcaggataactcctactgattctcgatgggttggagcttggtggcttaatttccttgtgtctggactattctccattatttcttccataccattctttttcttgccccaaactccaaataaaccacaaaaagaaagaaaagcttcactgtctttgcatgtgctggaaacaaatgatgaaaaggatcaaacagctaatttgaccaatcaaggaaaaaatattaccaaaaatgtgactggttttttccagtcttttaaaagcatccttactaatcccctgtatgttatgtttgtgcttttgacgttgttacaagtaagcagctatattggtgcttttacttatgtcttcaaatacgtagagcaacagtatggtcagccttcatctaaggctaacatcttattgggagtcataaccatacctatttttgcaagtggaatgtttttaggaggatatatcattaaaaaattcaaactgaacaccgttggaattgccaaattctcatgttttactgctgtgatgtcattgtccttttacctattatattttttcatactctgtgaaaacaaatcagttgccggactaaccatgacctatgatggaaataatccagtgacatctcatagagatgtaccactttcttattgcaactcagactgcaattgtgatgaaagtcaatgggaaccagtctgtggaaacaatggaataacttacatctcaccctgtctagcaggttgcaaatcttcaagtggcaataaaaagcctatagtgttttacaactgcagttgtttggaagtaactggtctccagaacagaaattactcagcccatttgggtgaatgcccaagagatgatgcttgtacaaggaaattttacttttttgttgcaatacaagtcttgaatttatttttctctgcacttggaggcacctcacatgtcatgctgattgttaaaattgttcaacctgaattgaaatcacttgcactgggtttccactcaatggttatacgagcactaggaggaattctagctccaatatattttggggctctgattgatacaacgtgtataaagtggtccaccaacaactgtggcacacgtgggtcatgtaggacatataattccacatcattttcaagggtctacttgggcttgtcttcaatgttaagagtctcatcacttgttttatatattatattaatttatgccatgaagaaaaaatatcaagagaaagatatcaatgcatcagaaaatggaagtgtcatggatgaagcaaacttagaatccttaaataaaaataaacattttgtcccttctgctggggcagatagtgaaacacattgttaaggggagaaaaaaagccacttctgcttctgtgtttccaaacagcattgcattgattcagtaagatgttatttttgaggagttcctggtcctttcactaagaatttccacatcttttatggtggaagtataaataagcctatgaacttataataaaacaaactgtaggtagaaaaaatgagagtactcattgttacattatagctacatatttgtggttaaggttagactatatgatccatacaaattaaagtgagagacatggttactgtgtaataaaagaaaaaatacttgttcaggtaattctaattcttaataaaacaaatgagtatcatacaggtagaggttaaaaaggaggagctagattcatatcctaagtaaagagaaatgcctagtgtctattttattaaacaaacaaacacagagtttgaactataatactaaggcctgaagtctagcttggatatatgctacaataatatctgttactcacataaaattatatatttcacagactttatcaatgtataattaacaattatcttgtttaagtaaatttagaatacatttaagtattgtggaagaaataaagacattccaatatttgcaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:10599 -> Molecular function: GO:0015347 [sodium-independent organic anion transmembrane transporter activity] evidence: TAS
            GeneID:10599 -> Biological process: GO:0008206 [bile acid metabolic process] evidence: TAS
            GeneID:10599 -> Biological process: GO:0015711 [organic anion transport] evidence: TAS
            GeneID:10599 -> Biological process: GO:0015721 [bile acid and bile salt transport] evidence: TAS
            GeneID:10599 -> Biological process: GO:0043252 [sodium-independent organic anion transport] evidence: TAS
            GeneID:10599 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
            GeneID:10599 -> Biological process: GO:0055085 [transmembrane transport] evidence: TAS
            GeneID:10599 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
            GeneID:10599 -> Cellular component: GO:0005887 [integral to plasma membrane] evidence: TAS
            GeneID:10599 -> Cellular component: GO:0016020 [membrane] evidence: TAS
            GeneID:10599 -> Cellular component: GO:0016323 [basolateral plasma membrane] evidence: IEA

by @meso_cacase at DBCLS
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