LOCUS       NM_004571               4997 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens PBX/knotted 1 homeobox 1 (PKNOX1), mRNA.
ACCESSION   NM_004571
VERSION     NM_004571.3  GI:37595549
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4997)
  AUTHORS   Bol,S.M., Booiman,T., van Manen,D., Bunnik,E.M., van Sighem,A.I.,
            Sieberer,M., Boeser-Nunnink,B., de Wolf,F., Schuitemaker,H.,
            Portegies,P., Kootstra,N.A. and van 't Wout,A.B.
  TITLE     Single nucleotide polymorphism in gene encoding transcription
            factor Prep1 is associated with HIV-1-associated dementia
  JOURNAL   PLoS ONE 7 (2), E30990 (2012)
   PUBMED   22347417
  REMARK    GeneRIF: Single nucleotide polymorphism in gene encoding
            transcription factor Prep1 is associated with HIV-1-associated
            dementia
REFERENCE   2  (bases 1 to 4997)
  AUTHORS   Iotti,G., Longobardi,E., Masella,S., Dardaei,L., De Santis,F.,
            Micali,N. and Blasi,F.
  TITLE     Homeodomain transcription factor and tumor suppressor Prep1 is
            required to maintain genomic stability
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 108 (29), E314-E322 (2011)
   PUBMED   21715654
  REMARK    GeneRIF: The tumor suppressor role of Prep1 is associated with the
            maintenance of genomic stability.
REFERENCE   3  (bases 1 to 4997)
  AUTHORS   Luciano,M., Hansell,N.K., Lahti,J., Davies,G., Medland,S.E.,
            Raikkonen,K., Tenesa,A., Widen,E., McGhee,K.A., Palotie,A.,
            Liewald,D., Porteous,D.J., Starr,J.M., Montgomery,G.W.,
            Martin,N.G., Eriksson,J.G., Wright,M.J. and Deary,I.J.
  TITLE     Whole genome association scan for genetic polymorphisms influencing
            information processing speed
  JOURNAL   Biol Psychol 86 (3), 193-202 (2011)
   PUBMED   21130836
REFERENCE   4  (bases 1 to 4997)
  AUTHORS   Rosales-Avina,J.A., Torres-Flores,J., Aguilar-Lemarroy,A.,
            Gurrola-Diaz,C., Hernandez-Flores,G., Ortiz-Lazareno,P.C.,
            Lerma-Diaz,J.M., de Celis,R., Gonzalez-Ramella,O.,
            Barrera-Chaires,E., Bravo-Cuellar,A. and Jave-Suarez,L.F.
  TITLE     MEIS1, PREP1, and PBX4 are differentially expressed in acute
            lymphoblastic leukemia: association of MEIS1 expression with higher
            proliferation and chemotherapy resistance
  JOURNAL   J. Exp. Clin. Cancer Res. 30, 112 (2011)
   PUBMED   22185299
  REMARK    GeneRIF: High levels of MEIS1 and PREP1, and low levels of PBX4
            expression were founded in samples of patients with ALL.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4997)
  AUTHORS   Bernardi,E., Deflorian,G., Pezzimenti,F., Diaz,V.M., Mione,M. and
            Blasi,F.
  TITLE     Characterization of the regulatory region of the zebrafish Prep1.1
            gene: analogies to the promoter of the human PREP1
  JOURNAL   PLoS ONE 5 (12), E15047 (2010)
   PUBMED   21203543
  REMARK    GeneRIF: analysis of the regulatory region of the zebrafish Prep1.1
            gene and the promoter of human PREP1
            Erratum:[PLoS One. 2011;6(4).
            doi:10.1371/annotation/6de90ec9-0314-40ec-b634-27373373aabc.
            Pezzinenti, Federica [corrected to Pezzimenti, Federica]]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4997)
  AUTHORS   Berthelsen,J., Viggiano,L., Schulz,H., Ferretti,E., Consalez,G.G.,
            Rocchi,M. and Blasi,F.
  TITLE     PKNOX1, a gene encoding PREP1, a new regulator of Pbx activity,
            maps on human chromosome 21q22.3 and murine chromosome 17B/C
  JOURNAL   Genomics 47 (2), 323-324 (1998)
   PUBMED   9479508
REFERENCE   7  (bases 1 to 4997)
  AUTHORS   LeBrun,D.P., Matthews,B.P., Feldman,B.J. and Cleary,M.L.
  TITLE     The chimeric oncoproteins E2A-PBX1 and E2A-HLF are concentrated
            within spherical nuclear domains
  JOURNAL   Oncogene 15 (17), 2059-2067 (1997)
   PUBMED   9366523
REFERENCE   8  (bases 1 to 4997)
  AUTHORS   Chen,H., Rossier,C., Nakamura,Y., Lynn,A., Chakravarti,A. and
            Antonarakis,S.E.
  TITLE     Cloning of a novel homeobox-containing gene, PKNOX1, and mapping to
            human chromosome 21q22.3
  JOURNAL   Genomics 41 (2), 193-200 (1997)
   PUBMED   9143494
REFERENCE   9  (bases 1 to 4997)
  AUTHORS   Phelan,M.L. and Featherstone,M.S.
  TITLE     Distinct HOX N-terminal arm residues are responsible for
            specificity of DNA recognition by HOX monomers and HOX.PBX
            heterodimers
  JOURNAL   J. Biol. Chem. 272 (13), 8635-8643 (1997)
   PUBMED   9079695
REFERENCE   10 (bases 1 to 4997)
  AUTHORS   Chang,C.P., Shen,W.F., Rozenfeld,S., Lawrence,H.J., Largman,C. and
            Cleary,M.L.
  TITLE     Pbx proteins display hexapeptide-dependent cooperative DNA binding
            with a subset of Hox proteins
  JOURNAL   Genes Dev. 9 (6), 663-674 (1995)
   PUBMED   7729685
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY196965.1, BC000735.2 and AA133342.1.
            On Oct 9, 2003 this sequence version replaced gi:28866954.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Y13613.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025085 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                AY196965.1         1-31
            32-132              BC000735.2         1-101
            133-4950            AY196965.1         134-4951
            4951-4997           AA133342.1         1-47                c
FEATURES             Location/Qualifiers
     source          1..4997
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.3"
     gene            1..4997
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /note="PBX/knotted 1 homeobox 1"
                     /db_xref="GeneID:5316"
                     /db_xref="HGNC:9022"
                     /db_xref="HPRD:03653"
                     /db_xref="MIM:602100"
     exon            1..132
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     exon            133..239
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       141
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75994231"
     variation       151
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371201606"
     variation       157
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370866616"
     variation       175
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201947360"
     misc_feature    183..185
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /note="upstream in-frame stop codon"
     variation       187
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146858763"
     CDS             189..1499
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /note="Pbx regulating protein-1; human homeobox-containing
                     protein; PBX/knotted homeobox 1; homeobox protein PREP-1"
                     /codon_start=1
                     /product="homeobox protein PKNOX1"
                     /protein_id="NP_004562.2"
                     /db_xref="GI:28866955"
                     /db_xref="CCDS:CCDS13692.1"
                     /db_xref="GeneID:5316"
                     /db_xref="HGNC:9022"
                     /db_xref="HPRD:03653"
                     /db_xref="MIM:602100"
                     /translation="

MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSEPDAEGVSPPPVESQTPMDVDKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTISPQGIVVPASALQQGNVAMATVAGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEEDAGALAPAHISGLVLENSDSLQ

"
     misc_feature    966..1136
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(966..980,984..986,1044..1046,1062..1064,1101..1103,
                     1107..1112,1119..1124,1128..1136)
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(972..974,981..983,1110..1112,1119..1124,1131..1133)
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    189..191
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /note="variably annotated as translation start"
     variation       207
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372802718"
     exon            240..367
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       249
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140607342"
     variation       293
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143734009"
     variation       314
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374571145"
     variation       326
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368748336"
     variation       337
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371041625"
     exon            368..539
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       396
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201874498"
     variation       424
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:148113718"
     variation       497
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376583194"
     variation       530
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:234781"
     exon            540..710
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       565
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:9976017"
     variation       638
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373121569"
     variation       644
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:76879928"
     exon            711..810
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       716
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113230836"
     variation       764
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200529595"
     variation       767
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372301185"
     variation       770
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371981717"
     variation       771
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374463906"
     variation       772
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199944249"
     variation       773
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199928026"
     variation       792
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202114509"
     variation       799
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201260136"
     variation       803
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200880395"
     exon            811..908
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       816
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:138899005"
     variation       829
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142921218"
     variation       834
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17115709"
     variation       835
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372849442"
     variation       836
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138151519"
     variation       840
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377090331"
     variation       895
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:149510960"
     variation       901
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143921536"
     exon            909..1037
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       973
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373951876"
     variation       981
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376883451"
     variation       1001
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148642401"
     variation       1005
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201583709"
     variation       1034
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186610951"
     exon            1038..1114
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     exon            1115..1287
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1174
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201879881"
     variation       1207
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374426020"
     variation       1212
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377682317"
     variation       1223
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370652452"
     variation       1246
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373371183"
     variation       1257
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376386330"
     variation       1261
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141136324"
     variation       1268
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188896357"
     exon            1288..4976
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1297
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201478576"
     variation       1323
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146209092"
     variation       1325
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367682347"
     variation       1326
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371162644"
     variation       1355
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372297622"
     variation       1379
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201263162"
     variation       1400
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201942352"
     variation       1436
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150726625"
     variation       1463
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368363368"
     variation       1464
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375619701"
     variation       1469
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140174291"
     variation       1471
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202131670"
     variation       1518
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376208238"
     variation       1525
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:371433559"
     variation       1590
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1064284"
     variation       1639
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11910392"
     variation       1659..1676
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="gtgtgtgtgt"
                     /replace="gtgtgtgtgtgtgtgtgt"
                     /db_xref="dbSNP:9325621"
     variation       1659..1674
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="gtgtgtgtgtgtgtgt"
                     /db_xref="dbSNP:140608702"
     variation       1659..1668
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="gtgtgtgtgt"
                     /db_xref="dbSNP:36206482"
     variation       1659..1666
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="gtgtgtgt"
                     /db_xref="dbSNP:112515074"
     variation       1659..1660
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="gt"
                     /db_xref="dbSNP:375371332"
     variation       1676
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73235410"
     variation       1678
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201243901"
     variation       1680..1689
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="tgtgtgtgtg"
                     /db_xref="dbSNP:58087112"
     variation       1680
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7278543"
     variation       1681
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199546143"
     variation       1682..1691
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="tgtgtgtgtgtgtgtgtgtg"
                     /db_xref="dbSNP:370050515"
     variation       1682
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3838120"
     variation       1684
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:13050372"
     variation       1690..1699
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="tgcgtgtgtg"
                     /db_xref="dbSNP:68042309"
     variation       1690
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:9754199"
     variation       1694
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113882840"
     variation       1699..1706
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="gcgtgtgt"
                     /db_xref="dbSNP:71808694"
     variation       1700
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376290612"
     variation       1723
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:62219526"
     variation       1740
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191844776"
     variation       1886
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:184389988"
     variation       1938
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371659599"
     variation       2020
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375725745"
     variation       2100
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190178128"
     STS             2195..2296
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /standard_name="WI-16888"
                     /db_xref="UniSTS:56495"
     STS             2221..2534
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /standard_name="G48510"
                     /db_xref="UniSTS:95570"
     variation       2224
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:181840413"
     variation       2226
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3403"
     variation       2337..2345
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="aaatttttg"
                     /db_xref="dbSNP:201465872"
     variation       2345
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17179001"
     variation       2391
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187372256"
     variation       2458
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142958691"
     variation       2516
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151096350"
     variation       2526
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141034128"
     variation       2674
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:73906406"
     variation       2699
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:234735"
     variation       2716
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:114660881"
     STS             2875..3147
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /standard_name="G48511"
                     /db_xref="UniSTS:95571"
     variation       2890
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190541960"
     variation       3134
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:180706691"
     variation       3164
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:77084451"
     variation       3187
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185094154"
     variation       3200
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:234736"
     variation       3223..3224
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:34926274"
     variation       3267..3268
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:72262444"
     variation       3285
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7275621"
     variation       3354
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189999648"
     STS             3395..3528
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /standard_name="D17S610"
                     /db_xref="UniSTS:46230"
     variation       3405
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182583263"
     variation       3409
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141598564"
     variation       3474
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185619229"
     variation       3478
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191760056"
     variation       3507
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111320868"
     variation       3550
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138122466"
     variation       3552
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376485356"
     variation       3613
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374505547"
     variation       3688
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183636018"
     variation       3689
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189023859"
     variation       3693
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149542189"
     variation       3709
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376936054"
     variation       3712..3713
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="tccctcaccaccctccgtctcttcg"
                     /db_xref="dbSNP:141407897"
     variation       3727..3728
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="ac"
                     /db_xref="dbSNP:71195909"
     variation       3729
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112957555"
     variation       3737..3738
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="tccctcaccaccctccgtctcttcg"
                     /db_xref="dbSNP:74278009"
     variation       3737
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76064267"
     variation       3743
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:378528"
     variation       3763
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148255872"
     variation       3864
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193098398"
     variation       3877
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:117553406"
     variation       3996
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374503004"
     variation       4051
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:234737"
     variation       4053
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141253574"
     variation       4101
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:234738"
     variation       4126
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:234739"
     variation       4156
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2839628"
     variation       4234
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146227772"
     variation       4236
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:234740"
     variation       4287
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371201755"
     variation       4310
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2839629"
     variation       4344
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:115975867"
     variation       4378..4379
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:111813527"
     variation       4427..4429
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="ttc"
                     /db_xref="dbSNP:370890678"
     variation       4537
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:78748402"
     variation       4565..4566
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="ca"
                     /replace="tg"
                     /db_xref="dbSNP:34670122"
     variation       4565
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:438889"
     variation       4566
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373477"
     variation       4573
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375586060"
     variation       4590
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116177078"
     variation       4660
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:7936"
     STS             4720..4863
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /standard_name="STS-T84037"
                     /db_xref="UniSTS:80586"
     STS             4740..4864
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /standard_name="D21S1938"
                     /db_xref="UniSTS:21289"
     STS             4769..4867
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /standard_name="SHGC-52028"
                     /db_xref="UniSTS:4030"
     variation       4820
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182159151"
     variation       4828..4834
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="ttcgttc"
                     /db_xref="dbSNP:144928489"
     variation       4829..4835
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="tcgttct"
                     /db_xref="dbSNP:55923175"
     variation       4834
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace=""
                     /replace="ttcgttc"
                     /db_xref="dbSNP:72003656"
     variation       4846
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186840063"
     variation       4857
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139203375"
     polyA_signal    4958..4963
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
     polyA_site      4975
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
     polyA_site      4976
                     /gene="PKNOX1"
                     /gene_synonym="pkonx1c; PREP1"
ORIGIN      

gcgtcgccctcctcccattgagcgaggctgtgtcgcgtggcccagcgtcggcgtgacggttggacgcgggcgcggcactgcgggtcccgattgctgcagccgcttgtcagtgtgatgaagattggcacccagacaccattcgcttttcacccaagatgatttgatgtcttataaaactctgatgaaccatgatggctacacagacattaagtatagacagctatcaagatgggcaacagatgcaagtagtaacagagttaaagacagaacaagatccaaactgctctgaacccgatgcagaaggagtgagccctccccctgtggagtctcagaccccgatggatgtggacaagcaggccatttataggcatccactatttccattattagctttgttgtttgaaaaatgtgaacaatctacacagggctctgaaggcacaacttctgccagttttgatgtagacatcgaaaattttgtaagaaagcaagagaaggaagggaaacctttcttttgtgaagatccagaaactgataatttaatggtaaaagcaatccaggttttgcgcattcatcttcttgagctggaaaaggttaacgaactctgcaaagatttctgcagtcgatacattgcttgtctgaaaacaaaaatgaacagtgaaactctgttgagtggagagcctggaagcccgtactcaccagtgcagtcccagcagattcaaagtgccatcacaggcaccatcagccctcagggaattgtggtgccggcgtccgcgctgcagcagggaaacgtagccatggcgacggtggcaggtggcacagtgtatcagcctgtcacggtcgtcactccccaaggccaagtggtcacacagacattgtcgcctgggacaattaggatccagaactcccagcttcagttacagttaaaccaagatctcagcatcttgcatcaagatgatggttcatctaagaacaagaggggcgtcctgccaaagcatgccacgaacgtgatgcggtcctggctcttccagcacatcgggcatccctacccaacagaggatgagaaaaaacagattgctgctcagacaaatttgacactactccaagtcaacaactggttcatcaatgccagaagacgaattcttcagccaatgttggattcaagttgttcagagacccccaaaacaaagaaaaaaactgctcagaaccggccagttcagaggttttggcctgattctattgcatcaggagtcgcacagccaccgccgagcgagctcaccatgtcggaaggagctgttgtcaccatcaccacgcccgtgaacatgaacgtggacagccttcagtctctgtcctcggacggggccaccctggcggtgcagcaggtcatgatggcagggcagagcgaggacgagtctgtggacagcacagaggaggatgcgggtgccctggcccctgcccacatcagcgggctggtcttggagaacagtgactccctgcagtaggggcaggagcagacgcacctgactttttggagtttgcacagcaaacattttacacagttttatttctaatatgttttatatgtagatatagaagagtgcacttttgtatttcatagtaagcttaaagcgcgtctttgccggtgcagcgacttctttcaagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcgtgtgtgcgtgtgtgtggatttttaaagaaattctttaaaggtttaacgctagattgtgaggaatgacacaccactccctccccaccttgaatccctaattagattaaggaatagcgctgccattttctaaaccgtgatgcggttgtcacttagttctgtggttccagcagatctcagtgggctggttgatttgtgtggcccatggatttgaaagaagctgctgcacccgaaactgccagtgtgcggtgacaacggcacacgcctagactgagtgtggtttcgtcgtgagtggatggacggcaagcttagcaagcctaagtcccctcatgttcagtgagcctgtttcatttgctatatagaaaaagaaactcctatttttaccttgctggaattattggataaaaaagctatttttataaattcgttatgaattggatgatgactatattgaggataaaatttctagagaagaaacaatacatgcttgctattaatatttcaatttggaatgttctgaattgaccaaatttaatgaacctgcccaaagttagctaccgttccatggttctttgctctccccgggtagtgatgaacatttactactataaaagaaacagctatttaatgaaattttgatatctgcaaatttttgttgatatgtaatgctcagattgcattttacacttgatctaaacatatatcgaaagatatctgctaaacaggacttcaggtaagtgaggtgaaatggtagccagtgacccgttaggagctctcaccgtacatactccagtctaatttaaatctgaccacagttgcatggtcgctttaccatgttagctgtgtattgttttaaaagttttaacttcaaaatatgttatgcacagaatgtttattataaactaatataaaatgtgctctaccccattggctcagagctagggcaaacagcagatattcagactttattacttaactagcggacatccctggagtcccagcagcgagctggtctggcgagggcacctcggcagcccccacgggttggctcctacgtttgcgtttgtggctggtctcctggtgtcagtgttctcttgtacgttgttgctttcgacttttcagagccctcctgctcacttgaccacgtgagatttggaataactgtaggacttctgtttcctggtaacaagatgaaccgagagagtgggctgggttctgttttctttggttttgatttgttttcattgtttacttaggagtggtgctttttctcagaaaacaggccacggtgtttcatacagaatgtcttcatatcatctgaaatggtatggctgaagttcatttgtttacagggtcgggaatgtcttcagttcttgagagtcaacagtaatgattggttgtaagccaagggacattttaagctagtgaagagttttttctggaattgatttttcccaaaagaatatattaattgaggttaagaagtcagtgggaaacacacagaaatttgttttaaaatctttcaggagctttactgaaagacttggttatcaagtcttttggggagagaatgacattttttttttgagacagagttttgctcttgttgcccaggctggagggcaatggtgcaatctcagctcactgcaacctccacctcttatgttcaagcaattctccttccttagcctcctgagtagctgggattacaggcatgcgccaccacacccggctaattttgtatttttagtagagatgggtttctccatgttggtcgggctggtctcgaactcccgacctcaggtgatctgcctgcctcagcctcccaaagtgctgggattacaggtgtgagccaccgcgcccggccgagaatgacatcttaaagccaccattgcgttcctcatttgtgaactgtcttctcatattttaagtcaagtctataagatcatttttaacctaagttccaactttgttggactccttaaaataagcacccatgaaagccagccagcccttcctccttccctcaccaccctccgtctcttcggctgcttgctctttagtgtagattagtggaagccattcacagaatgtagactcatgtataggtcaccgtttctttcccccactagaaatcacattcactaagcagtggattgaatttaagagtgctgcccctgcccggcgcagtagggcgtgcctctagttccagctactcgggagtctgaggcagaggatggcatgtgccaggagtttgaggctgcagtgcactatgcttgcacctgtgaatagccactgcactccatcttgggcaacacagtgagacccccatctataaaaagagagcactgcctgaacctcggtggcactgggaagctctggcctgagagttaaacacccatgctgaatgatacagtgtgcattctctccagctgcaaactttcttcaactttcctaaattcttactaaattcagaggaataggataaagatcacttagagaaagggtgcttatggacatagcctgagtttcctttaacctctctgcaatgggtgcttttaactagcttctacatggcaagctgtttcagtttgcaaaatcactgcccagcatgtttgaggtcagttggcaccttaaaacacctgttctccagcccttggacagtggagagaatctgtaaaagtgtgaccccctctaagatttcgttttaaatgatcagattcggttccagttttattcttgttgagtttttccctatgaaggctccttttgaatgtgtcttgagacccaaattgagcatgttgctgttattcctgccctgcacctgtggagcaggagtggcagggctggctgtgctgggttccagctcgctcccaccgagggactagcttggcctttgcgctttgattccagatagtaagatgagtggaagtgtttatcgagcatgcaaaagaaaccctcacggctaagggctctgggagttgtgtctgtgtgacctgagagtgatccatctcctgcctgtgtgaggtagcagtgggcacttttcattgagacaaactccagggtgtccagagggggttctgccccttgtgaaggcccattcctggcacttagagacagaaagaactcagcaatctttcgttctagttatattcggtctttgaaactgacaatctttgaaatgtgaatactgtaacaatatgttttcttggattgttgtctttaaaaaggatttttgtgaagcaattgatttatcaaagcaaaaaaattaaaaatagaaacttgcaaaaaaaaaaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:5316 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: TAS
            GeneID:5316 -> Molecular function: GO:0003705 [RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:5316 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:5316 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IEA
            GeneID:5316 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA
            GeneID:5316 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
            GeneID:5316 -> Biological process: GO:0030217 [T cell differentiation] evidence: IEA
            GeneID:5316 -> Biological process: GO:0030218 [erythrocyte differentiation] evidence: IEA
            GeneID:5316 -> Biological process: GO:0043010 [camera-type eye development] evidence: IEA
            GeneID:5316 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:5316 -> Cellular component: GO:0005667 [transcription factor complex] evidence: IEA
            GeneID:5316 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA