GGRNA Home | Help | Advanced search

2024-03-28 22:01:29, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_002700               1182 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens POU class 4 homeobox 3 (POU4F3), mRNA.
ACCESSION   NM_002700
VERSION     NM_002700.2  GI:225735566
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1182)
  AUTHORS   Lee,H.K., Park,H.J., Lee,K.Y., Park,R. and Kim,U.K.
  TITLE     A novel frameshift mutation of POU4F3 gene associated with
            autosomal dominant non-syndromic hearing loss
  JOURNAL   Biochem. Biophys. Res. Commun. 396 (3), 626-630 (2010)
   PUBMED   20434433
  REMARK    GeneRIF: This is the first report of a POU4F3 mutation in Asia, and
            moreover our data suggest that further investigation will need to
            delineate ethnicity-specific genetic background for autosomal
            dominant non-syndromic hearing loss within Asian populations.
            Erratum:[Biochem Biophys Res Commun. 2010 Aug 6;398(4):790]
REFERENCE   2  (bases 1 to 1182)
  AUTHORS   de Heer,A.M., Huygen,P.L., Collin,R.W., Kremer,H. and Cremers,C.W.
  TITLE     Mild and variable audiometric and vestibular features in a third
            DFNA15 family with a novel mutation in POU4F3
  JOURNAL   Ann. Otol. Rhinol. Laryngol. 118 (4), 313-320 (2009)
   PUBMED   19462854
  REMARK    GeneRIF: Cochleovestibular characteristics were investigated in a
            Dutch DFNA15 family with a novel POU4F3 mutation, L223P.
REFERENCE   3  (bases 1 to 1182)
  AUTHORS   van Drunen,F.J., Pauw,R.J., Collin,R.W., Kremer,H., Huygen,P.L. and
            Cremers,C.W.
  TITLE     Vestibular impairment in a Dutch DFNA15 family with an L289F
            mutation in POU4F3
  JOURNAL   Audiol. Neurootol. 14 (5), 303-307 (2009)
   PUBMED   19372648
  REMARK    GeneRIF: extended subset of L289F POU4F3 mutation carriers varied
            from normal to areflexia in cochleovestibular disease
REFERENCE   4  (bases 1 to 1182)
  AUTHORS   Pauw,R.J., van Drunen,F.J., Collin,R.W., Huygen,P.L., Kremer,H. and
            Cremers,C.W.
  TITLE     Audiometric characteristics of a Dutch family linked to DFNA15 with
            a novel mutation (p.L289F) in POU4F3
  JOURNAL   Arch. Otolaryngol. Head Neck Surg. 134 (3), 294-300 (2008)
   PUBMED   18347256
  REMARK    GeneRIF: report presents a detailed audiometric analysis of a Dutch
            family linked to DFNA15 with a novel mutation (p.L289F) in the
            POU4F3 gene
REFERENCE   5  (bases 1 to 1182)
  AUTHORS   Frenz,C.M. and Lefebvre,P.P.
  TITLE     Molecular modelling insights into DFNA15 mediated enhancement of
            POU4F3 stability
  JOURNAL   Int J Comput Biol Drug Des 1 (3), 295-301 (2008)
   PUBMED   20054994
  REMARK    GeneRIF: Molecular modelling is utilised to propose a mechanism of
            stability enhancement, via an interaction between the truncated
            POU(HD) domain and the POU(S) domain of the transcription factor.
REFERENCE   6  (bases 1 to 1182)
  AUTHORS   Weiss,S., Gottfried,I., Mayrose,I., Khare,S.L., Xiang,M.,
            Dawson,S.J. and Avraham,K.B.
  TITLE     The DFNA15 deafness mutation affects POU4F3 protein stability,
            localization, and transcriptional activity
  JOURNAL   Mol. Cell. Biol. 23 (22), 7957-7964 (2003)
   PUBMED   14585957
  REMARK    GeneRIF: Mutant POU4F3 loses most of its transcriptional activity
            and most of its ability to bind to DNA. The mutation causes
            autosomal-dominant nonsyndromic hearing loss and eventually leads
            to hair cell morbidity in affected family H members.
REFERENCE   7  (bases 1 to 1182)
  AUTHORS   Leonard,J.H., Cook,A.L., Van Gele,M., Boyle,G.M., Inglis,K.J.,
            Speleman,F. and Sturm,R.A.
  TITLE     Proneural and proneuroendocrine transcription factor expression in
            cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma
  JOURNAL   Int. J. Cancer 101 (2), 103-110 (2002)
   PUBMED   12209986
  REMARK    GeneRIF: Proneural and proneuroendocrine transcription factor
            expression in cutaneous mechanoreceptor (Merkel) cells and Merkel
            cell carcinoma
            Erratum:[Int J Cancer. 2004 Dec 20;112(6):1086]
REFERENCE   8  (bases 1 to 1182)
  AUTHORS   Vahava,O., Morell,R., Lynch,E.D., Weiss,S., Kagan,M.E., Ahituv,N.,
            Morrow,J.E., Lee,M.K., Skvorak,A.B., Morton,C.C., Blumenfeld,A.,
            Frydman,M., Friedman,T.B., King,M.C. and Avraham,K.B.
  TITLE     Mutation in transcription factor POU4F3 associated with inherited
            progressive hearing loss in humans
  JOURNAL   Science 279 (5358), 1950-1954 (1998)
   PUBMED   9506947
REFERENCE   9  (bases 1 to 1182)
  AUTHORS   Erkman,L., McEvilly,R.J., Luo,L., Ryan,A.K., Hooshmand,F.,
            O'Connell,S.M., Keithley,E.M., Rapaport,D.H., Ryan,A.F. and
            Rosenfeld,M.G.
  TITLE     Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and
            visual system development
  JOURNAL   Nature 381 (6583), 603-606 (1996)
   PUBMED   8637595
REFERENCE   10 (bases 1 to 1182)
  AUTHORS   Xiang,M., Zhou,L., Macke,J.P., Yoshioka,T., Hendry,S.H., Eddy,R.L.,
            Shows,T.B. and Nathans,J.
  TITLE     The Brn-3 family of POU-domain factors: primary structure, binding
            specificity, and expression in subsets of retinal ganglion cells
            and somatosensory neurons
  JOURNAL   J. Neurosci. 15 (7 PT 1), 4762-4785 (1995)
   PUBMED   7623109
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC011396.4.
            This sequence is a reference standard in the RefSeqGene project.
            On Mar 28, 2009 this sequence version replaced gi:4505964.
            
            Summary: This gene encodes a member of the POU-domain family of
            transcription factors. POU-domain proteins have been observed to
            play important roles in control of cell identity in several
            systems. This protein is found in the retina and may play a role in
            determining or maintaining the identities of a small subset of
            visual system neurons. Defects in this gene are the cause of
            non-syndromic sensorineural deafness autosomal dominant type 15.
            [provided by RefSeq, Mar 2009].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC104923.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025092 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-209               AC011396.4         77453-77661         c
            210-1182            AC011396.4         76165-77137         c
FEATURES             Location/Qualifiers
     source          1..1182
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q32"
     gene            1..1182
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /note="POU class 4 homeobox 3"
                     /db_xref="GeneID:5459"
                     /db_xref="HGNC:9220"
                     /db_xref="HPRD:03911"
                     /db_xref="MIM:602460"
     STS             1..1182
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /db_xref="UniSTS:483311"
     exon            1..209
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    48..50
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /note="upstream in-frame stop codon"
     variation       64
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374959341"
     CDS             90..1106
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /note="brn-3C; brain-3C; brain-specific homeobox/POU
                     domain protein 3C"
                     /codon_start=1
                     /product="POU domain, class 4, transcription factor 3"
                     /protein_id="NP_002691.1"
                     /db_xref="GI:4505965"
                     /db_xref="CCDS:CCDS4281.1"
                     /db_xref="GeneID:5459"
                     /db_xref="HGNC:9220"
                     /db_xref="HPRD:03911"
                     /db_xref="MIM:602460"
                     /translation="
MMAMNSKQPFGMHPVLQEPKFSSLHSGSEAMRRVCLPAPQLQGNIFGSFDESLLARAEALAAVDIVSHGKNHPFKPDATYHTMSSVPCTSTSSTVPISHPAALTSHPHHAVHQGLEGDLLEHISPTLSVSGLGAPEHSVMPAQIHPHHLGAMGHLHQAMGMSHPHTVAPHSAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAVH
"
     misc_feature    255..284
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q15319.1);
                     Region: POU-IV box"
     misc_feature    624..857
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /note="Found in Pit-Oct-Unc transcription factors; Region:
                     POU; smart00352"
                     /db_xref="CDD:197673"
     misc_feature    912..1088
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(912..926,930..932,981..983,999..1001,1038..1040,
                     1044..1049,1056..1061,1065..1073,1077..1082)
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(918..920,927..929,1047..1049,1056..1061,1068..1070)
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     STS             90..1106
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /db_xref="UniSTS:481349"
     variation       115
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377108685"
     variation       119
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369422757"
     STS             137..688
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /standard_name="Pou4f3"
                     /db_xref="UniSTS:276146"
     variation       159
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142405319"
     variation       179
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:28994879"
     variation       192
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147927112"
     exon            210..1182
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /inference="alignment:Splign:1.39.8"
     variation       211
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140527422"
     variation       268
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150485964"
     variation       280
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200080568"
     variation       303
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370712489"
     variation       319
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138310635"
     variation       321
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148830499"
     variation       334
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145218099"
     variation       337
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369750656"
     variation       342
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:377611813"
     variation       350
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137955775"
     variation       370
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200817820"
     variation       371
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142447260"
     variation       377
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146014340"
     variation       386
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:78523542"
     variation       398
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141235724"
     variation       419
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150802201"
     variation       467
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113137300"
     variation       492
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200286254"
     variation       494
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145372405"
     variation       510
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139312280"
     variation       512
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140857174"
     variation       517
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368466009"
     variation       566
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144725680"
     variation       578
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145741257"
     variation       579
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372436251"
     variation       580
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367737951"
     variation       598
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374993918"
     variation       602
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:148985828"
     variation       606
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142910284"
     variation       610
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:112188700"
     variation       615
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368239745"
     variation       638
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371111393"
     variation       752
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:61737151"
     variation       757
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909057"
     variation       778
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369368461"
     variation       815
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374487362"
     variation       817
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373030800"
     variation       827
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368459497"
     variation       831
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141089759"
     variation       838
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371875449"
     variation       855
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202212413"
     variation       881
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149975083"
     variation       888
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:137882322"
     variation       900
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375230760"
     variation       919
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140750705"
     variation       922
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113824781"
     variation       923
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370087069"
     variation       926
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:6885298"
     variation       938
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138424542"
     variation       954
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909056"
     variation       983
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373534299"
     variation       1037
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149303333"
     variation       1122
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13169862"
     variation       1135
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201569184"
     variation       1142
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369204165"
     variation       1154
                     /gene="POU4F3"
                     /gene_synonym="BRN3C; DFNA15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372538637"
ORIGIN      
cgctgagcagcgctcacttggagagcggcaagcaagctagacaagcctgattccatgtcacccgctgccaccctgccaggagcgcgaagatgatggccatgaactccaagcagcctttcggcatgcacccggtgctgcaagaacccaaattctccagtctgcactctggctccgaggccatgcgccgagtctgtctcccagccccgcagctgcagggtaatatatttggaagctttgatgagagcctgctggcacgcgccgaagctctggcggcggtggatatcgtctcccacggcaagaaccatccgttcaagcccgacgccacctaccataccatgagcagcgtgccctgcacgtccacttcgtccaccgtgcccatctcccacccagctgcgctcacctcacaccctcaccacgccgtgcaccagggcctcgaaggcgacctgctggagcacatctcgcccacgctgagtgtgagcggcctgggcgctccggaacactcggtgatgcccgcacagatccatccacaccacctgggcgccatgggccacctgcaccaggccatgggcatgagtcacccgcacaccgtggcccctcatagcgccatgcctgcatgcctcagcgacgtggagtcagacccgcgcgagctggaagccttcgccgagcgcttcaagcagcggcgcatcaagctgggggtgacccaggcggacgtgggcgcggctctggctaatctcaagatccccggcgtgggctcgctgagccaaagcaccatctgcaggttcgagtctctcactctctcgcacaacaacatgatcgctctcaagccggtgctccaggcctggttggaggaggccgaggccgcctaccgagagaagaacagcaagccagagctcttcaacggcagcgaacggaagcgcaaacgcacgtccatcgcggcgccggagaagcgttcactcgaggcctatttcgctatccagccacgtccttcatctgagaagatcgcggccatcgctgagaaactggaccttaaaaagaacgtggtgagagtctggttctgcaaccagagacagaaacagaaacgaatgaagtattcggctgtccactgattgcggcagggcgcagcgtcgggagccgggagagcctagtgctcatccctcccgggttcgggggatggttatcggg
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:5459 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:5459 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:5459 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:5459 -> Biological process: GO:0007601 [visual perception] evidence: TAS
            GeneID:5459 -> Biological process: GO:0007605 [sensory perception of sound] evidence: IEA
            GeneID:5459 -> Biological process: GO:0021562 [vestibulocochlear nerve development] evidence: IEA
            GeneID:5459 -> Biological process: GO:0031290 [retinal ganglion cell axon guidance] evidence: IEA
            GeneID:5459 -> Biological process: GO:0042472 [inner ear morphogenesis] evidence: IEA
            GeneID:5459 -> Biological process: GO:0042491 [auditory receptor cell differentiation] evidence: IEA
            GeneID:5459 -> Biological process: GO:0048675 [axon extension] evidence: IEA
            GeneID:5459 -> Biological process: GO:0050885 [neuromuscular process controlling balance] evidence: IEA
            GeneID:5459 -> Biological process: GO:0051402 [neuron apoptotic process] evidence: IEA
            GeneID:5459 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:5459 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.