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2024-04-19 23:44:12, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001427 3405 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens engrailed homeobox 2 (EN2), mRNA. ACCESSION NM_001427 VERSION NM_001427.3 GI:126090912 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 3405) AUTHORS Lin,P.I., Chien,Y.L., Wu,Y.Y., Chen,C.H., Gau,S.S., Huang,Y.S., Liu,S.K., Tsai,W.C. and Chiu,Y.N. TITLE The WNT2 gene polymorphism associated with speech delay inherent to autism JOURNAL Res Dev Disabil 33 (5), 1533-1540 (2012) PUBMED 22522212 REMARK GeneRIF: The WNT2 gene and EN2 gene may act in concert to influence the language development in autism. REFERENCE 2 (bases 1 to 3405) AUTHORS Choi,J., Ababon,M.R., Matteson,P.G. and Millonig,J.H. TITLE Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function JOURNAL Hum. Mol. Genet. 21 (7), 1566-1580 (2012) PUBMED 22180456 REMARK GeneRIF: The data demonstrates that the autism spectrum disorder-associated A-C intronic haplotype of the ENGRAILED2 gene is a transcriptional activator, and both CUX1 and NFIB mediate this activity. REFERENCE 3 (bases 1 to 3405) AUTHORS Morgan,R., Boxall,A., Bhatt,A., Bailey,M., Hindley,R., Langley,S., Whitaker,H.C., Neal,D.E., Ismail,M., Whitaker,H., Annels,N., Michael,A. and Pandha,H. TITLE Engrailed-2 (EN2): a tumor specific urinary biomarker for the early diagnosis of prostate cancer JOURNAL Clin. Cancer Res. 17 (5), 1090-1098 (2011) PUBMED 21364037 REMARK GeneRIF: findings show EN2 was expressed and secreted by prostate cancer (PC) cell lines and PC tissue but not by normal prostate tissue or stroma; presence of EN2 in urine was highly predictive of PC REFERENCE 4 (bases 1 to 3405) AUTHORS Sen,B., Singh,A.S., Sinha,S., Chatterjee,A., Ahmed,S., Ghosh,S. and Usha,R. TITLE Family-based studies indicate association of Engrailed 2 gene with autism in an Indian population JOURNAL Genes Brain Behav. 9 (2), 248-255 (2010) PUBMED 20050924 REMARK GeneRIF: Positive genetic correlation of EN2 with autism in the Indian population. GeneRIF: Observational study of gene-disease association. (HuGE Navigator) REFERENCE 5 (bases 1 to 3405) AUTHORS Yang,P., Shu,B.C., Hallmayer,J.F. and Lung,F.W. TITLE Intronic single nucleotide polymorphisms of engrailed homeobox 2 modulate the disease vulnerability of autism in a han chinese population JOURNAL Neuropsychobiology 62 (2), 104-115 (2010) PUBMED 20523082 REMARK GeneRIF: This study demonistrated that in Han chinese the association between the EN2 genetic polymorphism and autism. GeneRIF: Observational study of gene-disease association. (HuGE Navigator) REFERENCE 6 (bases 1 to 3405) AUTHORS Kozmik,Z., Sure,U., Ruedi,D., Busslinger,M. and Aguzzi,A. TITLE Deregulated expression of PAX5 in medulloblastoma JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92 (12), 5709-5713 (1995) PUBMED 7777574 REFERENCE 7 (bases 1 to 3405) AUTHORS Logan,C., Hanks,M.C., Noble-Topham,S., Nallainathan,D., Provart,N.J. and Joyner,A.L. TITLE Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions JOURNAL Dev. Genet. 13 (5), 345-358 (1992) PUBMED 1363401 REFERENCE 8 (bases 1 to 3405) AUTHORS Joyner,A.L., Herrup,K., Auerbach,B.A., Davis,C.A. and Rossant,J. TITLE Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox JOURNAL Science 251 (4998), 1239-1243 (1991) PUBMED 1672471 REFERENCE 9 (bases 1 to 3405) AUTHORS Poole,S.J., Law,M.L., Kao,F.T. and Lau,Y.F. TITLE Isolation and chromosomal localization of the human En-2 gene JOURNAL Genomics 4 (3), 225-231 (1989) PUBMED 2565873 REFERENCE 10 (bases 1 to 3405) AUTHORS Logan,C., Willard,H.F., Rommens,J.M. and Joyner,A.L. TITLE Chromosomal localization of the human homeo box-containing genes, EN1 and EN2 JOURNAL Genomics 4 (2), 206-209 (1989) PUBMED 2567700 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC008060.5 and H16179.1. This sequence is a reference standard in the RefSeqGene project. On Feb 23, 2007 this sequence version replaced gi:7710120. Summary: Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC104970.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025084, ERS025085 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-934 AC008060.5 88973-89906 935-3381 AC008060.5 93215-95661 3382-3405 H16179.1 1-24 c FEATURES Location/Qualifiers source 1..3405 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="7" /map="7q36" gene 1..3405 /gene="EN2" /note="engrailed homeobox 2" /db_xref="GeneID:2020" /db_xref="HGNC:3343" /db_xref="HPRD:08836" /db_xref="MIM:131310" STS 1..1296 /gene="EN2" /db_xref="UniSTS:488054" exon 1..934 /gene="EN2" /inference="alignment:Splign:1.39.8" misc_feature 97..99 /gene="EN2" /note="upstream in-frame stop codon" variation 102 /gene="EN2" /replace="c" /replace="t" /db_xref="dbSNP:371410446" variation 210 /gene="EN2" /replace="g" /replace="t" /db_xref="dbSNP:370541113" CDS 250..1251 /gene="EN2" /note="engrailed homolog 2; engrailed-2; hu-En-2; homeobox protein en-2" /codon_start=1 /product="homeobox protein engrailed-2" /protein_id="NP_001418.2" /db_xref="GI:7710121" /db_xref="CCDS:CCDS5940.1" /db_xref="GeneID:2020" /db_xref="HGNC:3343" /db_xref="HPRD:08836" /db_xref="MIM:131310" /translation="
MEENDPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSE
"
misc_feature 976..1155
/gene="EN2"
/note="Region: homeobox domain"
misc_feature 994..1152
/gene="EN2"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(994..996,1000..1002,1051..1053,1069..1071,
1108..1110,1114..1119,1126..1131,1135..1143,1147..1152)
/gene="EN2"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(997..999,1117..1119,1126..1131,1138..1140)
/gene="EN2"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 1075..1077
/gene="EN2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1153..1248
/gene="EN2"
/note="Engrailed homeobox C-terminal signature domain;
Region: Engrail_1_C_sig; pfam10525"
/db_xref="CDD:119045"
variation 277
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:193264681"
variation 360
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:77846527"
variation 397
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:377588499"
variation 420
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:199573836"
variation 585
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:377426405"
variation 610
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3735653"
variation 633
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375042010"
variation 653
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:112029171"
variation 849
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:80239010"
exon 935..3395
/gene="EN2"
/inference="alignment:Splign:1.39.8"
STS 940..1055
/gene="EN2"
/standard_name="EN2"
/db_xref="UniSTS:15616"
variation 969
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145749730"
variation 976
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371468430"
variation 986
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:148967146"
variation 987
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:144197066"
variation 990
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138007513"
variation 1006
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:75103128"
variation 1032
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373725366"
variation 1059
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112687347"
variation 1067
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:367902456"
variation 1083
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146535449"
variation 1125
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:141222652"
variation 1137
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145531356"
variation 1149
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:34614453"
variation 1158
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148064651"
variation 1173
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140822188"
variation 1179
/gene="EN2"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:56008230"
variation 1201
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2361689"
variation 1209
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142774508"
variation 1236
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:374787499"
variation 1238
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:367924841"
variation 1245
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149481945"
variation 1254
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:12674067"
variation 1255
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375061145"
variation 1284
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369675027"
variation 1285
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:192274449"
variation 1318
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:184624346"
variation 1344
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:374181653"
variation 1506
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:73734533"
variation 1634
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189436701"
variation 1660
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181376144"
variation 1670
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:207468873"
variation 1770
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:185936495"
variation 1776
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368761266"
variation 1825
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372780297"
variation 1828
/gene="EN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:368291486"
variation 1851
/gene="EN2"
/replace=""
/replace="g"
/db_xref="dbSNP:144219267"
variation 1861
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:56651365"
variation 1874
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:143878581"
variation 1876
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3808330"
variation 1955
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3808329"
variation 1964
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189617846"
variation 1981
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3808328"
variation 2001
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:10234087"
variation 2019..2022
/gene="EN2"
/replace=""
/replace="cttt"
/db_xref="dbSNP:111556743"
variation 2022..2025
/gene="EN2"
/replace=""
/replace="tctt"
/db_xref="dbSNP:371995609"
variation 2060
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139789685"
variation 2069
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3808327"
variation 2075
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:55729502"
variation 2076
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3808326"
variation 2131
/gene="EN2"
/replace="a"
/replace="t"
/db_xref="dbSNP:57599144"
variation 2159
/gene="EN2"
/replace="a"
/replace="c"
/db_xref="dbSNP:375798987"
variation 2186
/gene="EN2"
/replace=""
/replace="c"
/db_xref="dbSNP:113000817"
variation 2206
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370047096"
variation 2217
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:143914514"
variation 2235
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368877872"
variation 2244
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:4716597"
variation 2266
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181828936"
variation 2267
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369546982"
variation 2380
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:114134796"
variation 2446
/gene="EN2"
/replace="a"
/replace="t"
/db_xref="dbSNP:67027007"
variation 2530
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:186374442"
variation 2549
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:10949811"
variation 2559..2560
/gene="EN2"
/replace=""
/replace="ac"
/db_xref="dbSNP:113684257"
variation 2560..2563
/gene="EN2"
/replace=""
/replace="acac"
/db_xref="dbSNP:144874127"
variation 2579..2580
/gene="EN2"
/replace=""
/replace="aca"
/db_xref="dbSNP:72022210"
variation 2580..2581
/gene="EN2"
/replace=""
/replace="cac"
/db_xref="dbSNP:72575652"
variation 2581..2582
/gene="EN2"
/replace=""
/replace="a"
/replace="ac"
/replace="aca"
/db_xref="dbSNP:35869460"
variation 2581
/gene="EN2"
/replace="a"
/replace="c"
/db_xref="dbSNP:77385528"
variation 2584
/gene="EN2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200149777"
variation 2711
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:190966205"
variation 2733
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:117213382"
variation 2895
/gene="EN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370953015"
variation 2925
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:182759274"
variation 3044
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:118079538"
variation 3124
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146402842"
STS 3145..3324
/gene="EN2"
/standard_name="RH102827"
/db_xref="UniSTS:97161"
variation 3222..3223
/gene="EN2"
/replace=""
/replace="at"
/db_xref="dbSNP:371338740"
variation 3238..3239
/gene="EN2"
/replace=""
/replace="c"
/db_xref="dbSNP:34901594"
variation 3264
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139745969"
variation 3276
/gene="EN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:186998101"
variation 3299
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:115156116"
variation 3320
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373820948"
polyA_signal 3362..3367
/gene="EN2"
polyA_signal 3366..3371
/gene="EN2"
variation 3381
/gene="EN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56178493"
polyA_site 3395
/gene="EN2"
ORIGIN
tctctcatcgtctgggcgagcggggcggctcgtggtgtttctaacccagttcgtggattcaaaggtggctccgcgccgagcgcggccggcgacttgtaggacctcagccctggccgcggccgccgcgcacgccctcggaagactcggcggggtgggggcgcgggggtctccgtgtgcgccgcgggagggccgaaggctgatttggaagggcgtccccggagaaccagtgtgggatttactgtgaacagcatggaggagaatgaccccaagcctggcgaagcagcggcggcggtggagggacagcggcagccggaatccagccccggcggcggctcgggcggcggcggcggtagcagcccgggcgaagcggacaccgggcgccggcgggctctgatgctgcccgcggtcctgcaggcgcccggcaaccaccagcacccgcaccgcatcaccaacttcttcatcgacaacatcctgcggcccgagttcggccggcgaaaggacgcggggacctgctgtgcgggcgcgggaggaggaaggggcggcggagccggcggcgaaggcggcgcgagcggtgcggagggaggcggcggcgcgggcggctcggagcagctcttgggctcgggctcccgagagccccggcagaacccgccatgtgcgcccggcgcgggcgggccgctcccagccgccggcagcgactctccgggtgacggggaaggcggctccaagacgctctcgctgcacggtggcgccaagaaaggcggcgaccccggcggccccctggacgggtcgctcaaggcccgcggcttgggcggcggcgacctgtcggtgagctcggactcggacagctcgcaagccggcgccaacctgggcgcgcagcccatgctctggccggcgtgggtctactgtacgcgctactcggaccggccttcttcaggtcccaggtctcgaaaaccaaagaagaagaacccgaacaaagaggacaagcggccgcgcacggcctttaccgccgagcagctgcagaggctcaaggccgagttccagaccaacaggtacctgacggagcagcggcgccagagcctggcgcaggagctgagcctcaacgagtcacagatcaagatttggttccagaacaagcgcgccaagatcaagaaggccacgggcaacaagaacacgctggccgtgcacctcatggcacagggcttgtacaaccactccaccacagccaaggagggcaagtcggacagcgagtagggcggggggcatggaggccaggtctcagtccgcgctaaacaatgcaataatttaaaatcataaagggccagtgtataaagattataccagcattaatagtgaaaatattgtgtattagctaaggttctgaaatattctatgtatatatcatttacaggtggtataaaatccaaaatatctgactataaaatatttttttgagttttttgtgtttatgagattatgctaattttatgggtttttttcttttttgcgaagggggctgcttagggtttcacctttttttaatcccctaagctccattatatgacattggacacttttttattattccaaaagaagaaaaaattaaaacaacttgctgaagtccaaagattttttattgctgcatttcacacaactgtgaaccgaataaatagctcctatttggtctatgacttctgccactttgtttgtgttggcttggtgaggacagcaggaggggcccacacctcaagcctggaccagccacctcaaggccttggggagcttaggggacctggtgggagagaggggacttccagggtccttgggccagttctgggatttggccctgggaagcagcccagcgtaccccaggcctgctctgggaagtcggctccatgctcaccagcagccgcccaggcccgcagcctcacccggctccctctcctcaccctcctgcacctaactccctcctccttctcctttttcctcctcttcctccttcctccttcctcctgctcctcctttcttcttctttttcttctcctcctcctccttccttcctcctcctccttctctttcctcctcctcctcaccaagggcccaaccgtgtgcatacatcgtctgcgtctgtggtctgtgtcgctgtccccagtcccaccgcagtcctgccgcaggcctaaccctcctgccctgggcactgcctccatgcagaagcgcttcgaggttctggggctaaaggcctggggtgtgtggcctaaagcccaagagcggtggggcgaccctccttttggcttggccccaggaatttcctgtgactccaccagccatcatgggtgccagccagggtcccagaaatgaggccatggctcactgtttctgggcgggcagaaggctctgtagagggagatggcatcatctatcttcctttcctttttcttttcttccctatttttttctttttttcctttatttttttcttttcttggagtggctgcttctgctatagagaacattcttccaagataaatatgtgtgtttacacatatgtctgcatgcatgtgaacacacacacacacacacacacaccaggcgtgtttgagtccacagttctgaaacatgtggctaccttgtctttcaaaagaactcagaatcctccaggatctagaagaaggaagaaagtgtgtaaataatcatttcttatcatcactttttgtcttttcttgttttttaaaatatacattttatttttgaaggtgtggtacagtgtaaattaaatatattcaatatatttcccaccaagtacctatatatgtatataaacaaacacattatctatatataacgccacactgtcttctgtttagtgtatggggaaagaccaatccaactgtccatctgtggctgggacagcccagggggtgtgcccacggctgacccaggggtgtgcacacggctgagctgggagtcccgctggtctccctgaggactgagggtgaacttcgctctttgccttaaacctctttatttcattgcagtaatagttttacgttgtacataatagtgtaaacctttttaaaaaggaaagtataaaaacaaaagttgtaatttaaaagtctgaataaccatctgctgcttaggaaactcaatgaaatgacatgcctttttagcaggaagcaaagttggtttctgttttttgttttctttgttgttttagtttataaaacatgtgcattttacagttccagtatcaaatatttataatcttatgagaaatgaatgaatgtttctatttacaactgtgcttatcaaaattgtgaacacccccacccccgcatttttgtgtgttgaaattcttgaaggttacattaaataaaacaaaatctctttattataaaataaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:2020 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
GeneID:2020 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
GeneID:2020 -> Biological process: GO:0007275 [multicellular organismal development] evidence: TAS
GeneID:2020 -> Biological process: GO:0030901 [midbrain development] evidence: IEA
GeneID:2020 -> Biological process: GO:0030902 [hindbrain development] evidence: IEA
GeneID:2020 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
GeneID:2020 -> Biological process: GO:0048666 [neuron development] evidence: IEA
GeneID:2020 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
GeneID:2020 -> Cellular component: GO:0016020 [membrane] evidence: IEA
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@meso_cacase at
DBCLS
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