LOCUS       NM_001174147            5804 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens LIM homeobox transcription factor 1, beta (LMX1B),
            transcript variant 2, mRNA.
ACCESSION   NM_001174147
VERSION     NM_001174147.1  GI:292494914
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5804)
  AUTHORS   Zhou,T.B. and Qin,Y.H.
  TITLE     The signaling pathways of LMX1B and its role in glomerulosclerosis
  JOURNAL   J. Recept. Signal Transduct. Res. 32 (6), 285-289 (2012)
   PUBMED   23046462
  REMARK    GeneRIF: LMX1B is important in regulating type IV collagen gene
            expression in the GBM of the developing kidney and also has a
            likely role in regulating additional genes important in podocyte
            function and maintenance
            Review article
REFERENCE   2  (bases 1 to 5804)
  AUTHORS   Thanseem,I., Nakamura,K., Anitha,A., Suda,S., Yamada,K.,
            Iwayama,Y., Toyota,T., Tsujii,M., Iwata,Y., Suzuki,K.,
            Matsuzaki,H., Iwata,K., Sugiyama,T., Yoshikawa,T. and Mori,N.
  TITLE     Association of transcription factor gene LMX1B with autism
  JOURNAL   PLoS ONE 6 (8), E23738 (2011)
   PUBMED   21901133
  REMARK    GeneRIF: Data report on the association of LMX1B with autism,
            though it should be viewed with some caution considering the modest
            associations we report.
REFERENCE   3  (bases 1 to 5804)
  AUTHORS   Romero,P., Sanhueza,F., Lopez,P., Reyes,L. and Herrera,L.
  TITLE     c.194 A>C (Q65P) mutation in the LMX1B gene in patients with
            nail-patella syndrome associated with glaucoma
  JOURNAL   Mol. Vis. 17, 1929-1939 (2011)
   PUBMED   21850167
  REMARK    GeneRIF: c.194 A>C (Q65P) mutation is present in the LMX1B gene of
            the Chilean patients with nail-patella syndrome associated with
            glaucoma.
REFERENCE   4  (bases 1 to 5804)
  AUTHORS   Song,N.N., Xiu,J.B., Huang,Y., Chen,J.Y., Zhang,L., Gutknecht,L.,
            Lesch,K.P., Li,H. and Ding,Y.Q.
  TITLE     Adult raphe-specific deletion of Lmx1b leads to central serotonin
            deficiency
  JOURNAL   PLoS ONE 6 (1), E15998 (2011)
   PUBMED   21246047
  REMARK    GeneRIF: effect of lmx1b on gene expression regulation in the brain
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5804)
  AUTHORS   Dunston,J.A., Hamlington,J.D., Zaveri,J., Sweeney,E., Sibbring,J.,
            Tran,C., Malbroux,M., O'Neill,J.P., Mountford,R. and McIntosh,I.
  TITLE     The human LMX1B gene: transcription unit, promoter, and pathogenic
            mutations
  JOURNAL   Genomics 84 (3), 565-576 (2004)
   PUBMED   15498463
REFERENCE   6  (bases 1 to 5804)
  AUTHORS   Vollrath,D., Jaramillo-Babb,V.L., Clough,M.V., McIntosh,I.,
            Scott,K.M., Lichter,P.R. and Richards,J.E.
  TITLE     Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in
            nail-patella syndrome
  JOURNAL   Hum. Mol. Genet. 7 (7), 1091-1098 (1998)
   PUBMED   9618165
  REMARK    Erratum:[Hum Mol Genet 1998 Aug;7(8):1333]
REFERENCE   7  (bases 1 to 5804)
  AUTHORS   Chen,H., Lun,Y., Ovchinnikov,D., Kokubo,H., Oberg,K.C.,
            Pepicelli,C.V., Gan,L., Lee,B. and Johnson,R.L.
  TITLE     Limb and kidney defects in Lmx1b mutant mice suggest an involvement
            of LMX1B in human nail patella syndrome
  JOURNAL   Nat. Genet. 19 (1), 51-55 (1998)
   PUBMED   9590288
REFERENCE   8  (bases 1 to 5804)
  AUTHORS   Dreyer,S.D., Zhou,G., Baldini,A., Winterpacht,A., Zabel,B.,
            Cole,W., Johnson,R.L. and Lee,B.
  TITLE     Mutations in LMX1B cause abnormal skeletal patterning and renal
            dysplasia in nail patella syndrome
  JOURNAL   Nat. Genet. 19 (1), 47-50 (1998)
   PUBMED   9590287
REFERENCE   9  (bases 1 to 5804)
  AUTHORS   Iannotti,C.A., Inoue,H., Bernal,E., Aoki,M., Liu,L.,
            Donis-Keller,H., German,M.S. and Permutt,M.A.
  TITLE     Identification of a human LMX1 (LMX1.1)-related gene, LMX1.2:
            tissue-specific expression and linkage mapping on chromosome 9
  JOURNAL   Genomics 46 (3), 520-524 (1997)
   PUBMED   9441763
REFERENCE   10 (bases 1 to 5804)
  AUTHORS   Johnson,J.D., Zhang,W., Rudnick,A., Rutter,W.J. and German,M.S.
  TITLE     Transcriptional synergy between LIM-homeodomain proteins and basic
            helix-loop-helix proteins: the LIM2 domain determines specificity
  JOURNAL   Mol. Cell. Biol. 17 (7), 3488-3496 (1997)
   PUBMED   9199284
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL161908.13, BC113491.1,
            BC069588.1, AL161731.20 and EL952935.1.
            
            Summary: This gene encodes a member of LIM-homeodomain family of
            proteins containing two N-terminal zinc-binding LIM domains, 1
            homeodomain, and a C-terminal glutamine-rich domain. It functions
            as a transcription factor, and is essential for the normal
            development of dorsal limb structures, the glomerular basement
            membrane, the anterior segment of the eye, and dopaminergic and
            serotonergic neurons. Mutations in this gene are associated with
            nail-patella syndrome. Alternatively spliced transcript variants
            encoding different isoforms have been found for this gene.
            [provided by RefSeq, Mar 2010].
            
            Transcript Variant: This variant (2) uses an alternate donor splice
            site at the penultimate coding exon compared to variant 1,
            resulting in a longer isoform (2) containing an additional 7 aa
            protein segment compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC069588.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025088 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AL161908.13        64452-64477
            27-1037             BC113491.1         1-1011
            1038-1216           BC069588.1         957-1135
            1217-1314           BC113491.1         1170-1267
            1315-5414           AL161731.20        40443-44542
            5415-5804           EL952935.1         44-433
FEATURES             Location/Qualifiers
     source          1..5804
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33.3"
     gene            1..5804
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="LIM homeobox transcription factor 1, beta"
                     /db_xref="GeneID:4010"
                     /db_xref="HGNC:6654"
                     /db_xref="MIM:602575"
     exon            1..146
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     CDS             8..1216
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     LMX-1.2; LIM/homeobox protein 1.2; LIM/homeobox protein
                     LMX1B"
                     /codon_start=1
                     /product="LIM homeobox transcription factor 1-beta isoform
                     2"
                     /protein_id="NP_001167618.1"
                     /db_xref="GI:292494915"
                     /db_xref="CCDS:CCDS55342.1"
                     /db_xref="GeneID:4010"
                     /db_xref="HGNC:6654"
                     /db_xref="MIM:602575"
                     /translation="

MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGDHMNPYGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS

"
     misc_feature    173..331
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="The first LIM domain of Lmx1b; Region: LIM1_Lmx1b;
                     cd09371"
                     /db_xref="CDD:188757"
     misc_feature    order(173..175,182..184,236..238,245..247,254..256,
                     263..265,314..316,323..325)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188757"
     misc_feature    350..514
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="The second LIM domain of Lmx1a and Lmx1b; Region:
                     LIM2_Lmx1a_Lmx1b; cd09378"
                     /db_xref="CDD:188764"
     misc_feature    order(350..352,359..361,416..418,425..427,434..436,
                     443..445,500..502,509..511)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188764"
     misc_feature    677..835
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:238039"
     misc_feature    order(677..679,683..685,734..736,752..754,791..793,
                     797..802,809..814,818..826,830..835)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(680..682,800..802,809..814,821..823)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     STS             27..1314
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /db_xref="UniSTS:483257"
     variation       64
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376265443"
     STS             77..1216
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /db_xref="UniSTS:480873"
     variation       108
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375095510"
     variation       123
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367661538"
     exon            147..333
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       157
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148305192"
     variation       168
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371819068"
     variation       191
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371293980"
     variation       217
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374685767"
     variation       231
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2235058"
     variation       251
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909489"
     variation       258
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377436751"
     variation       259
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2235059"
     variation       302
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:141391682"
     exon            334..566
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       340
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138385790"
     variation       342
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370537843"
     variation       343
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144043214"
     variation       360
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:121909488"
     variation       373
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200350302"
     variation       376
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147293594"
     variation       379
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374078636"
     variation       399
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373429181"
     variation       400
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:190161633"
     variation       439
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375657880"
     variation       448
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2277158"
     variation       458
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149434820"
     variation       514
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368298608"
     variation       515
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199738980"
     variation       541
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:116316477"
     variation       542
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181422024"
     variation       549
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:148403563"
     variation       550
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375486982"
     variation       553
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34434402"
     variation       559
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142488434"
     variation       565
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370299750"
     exon            567..748
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       598
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146465341"
     variation       601
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139862413"
     variation       668
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909487"
     variation       673
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143407067"
     variation       675
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:121909491"
     variation       676
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146720578"
     variation       688
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147071667"
     variation       698
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909490"
     variation       730
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368736494"
     variation       733
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:13295990"
     exon            749..826
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       752
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909492"
     variation       790
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371560611"
     variation       814
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:121909486"
     exon            827..893
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     exon            894..1058
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       901
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373033856"
     variation       908
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376497496"
     variation       936
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369831428"
     variation       937
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112171815"
     variation       940
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145052881"
     variation       989
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373336352"
     variation       1021
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199580468"
     variation       1048
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376607391"
     exon            1059..5797
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       1066
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148940265"
     variation       1068
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147035553"
     variation       1113
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76277667"
     variation       1114
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10115304"
     variation       1115
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78770531"
     variation       1139
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375881049"
     variation       1157
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367916653"
     variation       1158
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143906016"
     variation       1159
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146476348"
     variation       1171
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148356178"
     variation       1178
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141496559"
     variation       1180
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200484654"
     variation       1207
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372183654"
     variation       1229
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375458623"
     variation       1237
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369706326"
     variation       1243
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10115373"
     variation       1254
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201442685"
     variation       1255
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376851692"
     variation       1256
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374778848"
     variation       1267
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10121481"
     variation       1295
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10115393"
     variation       1343
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113846301"
     variation       1371
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151191848"
     variation       1389
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181701033"
     variation       1470
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371380792"
     variation       1496
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111648919"
     variation       1654
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140325479"
     variation       1667
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71497630"
     variation       1693
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374016635"
     variation       1731
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112375232"
     variation       1800
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:34200683"
     variation       1849..1852
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="acac"
                     /db_xref="dbSNP:147813553"
     variation       1897
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138360048"
     variation       1924
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987413"
     variation       1964
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10987414"
     variation       2001
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143919006"
     variation       2100
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146268507"
     variation       2114
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10760450"
     variation       2148
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:28687510"
     variation       2151
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186360995"
     variation       2216
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189691069"
     variation       2322..2323
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:201556524"
     variation       2347
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138749439"
     variation       2366
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181187127"
     variation       2406
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374742119"
     variation       2456..2457
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:368812241"
     variation       2456
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368887101"
     variation       2471
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16929236"
     variation       2520
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73596779"
     variation       2544
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185183718"
     variation       2603..2607
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttt"
                     /db_xref="dbSNP:67078890"
     variation       2603..2604
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="g"
                     /replace="tgttt"
                     /db_xref="dbSNP:72111206"
     variation       2605
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:13300385"
     variation       2605
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="gtttt"
                     /replace="ttttg"
                     /db_xref="dbSNP:71493852"
     variation       2608..2632
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttttgttttgttttgttttgttt"
                     /db_xref="dbSNP:370075271"
     variation       2609
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:200514771"
     variation       2609
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:13299451"
     variation       2653
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttt"
                     /db_xref="dbSNP:10581734"
     variation       2657..2658
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttt"
                     /db_xref="dbSNP:59836255"
     variation       2689
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13299609"
     STS             2707..2916
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /standard_name="RH80030"
                     /db_xref="UniSTS:87680"
     variation       2710
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370649232"
     variation       2726
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189648333"
     variation       2735
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183329572"
     variation       2754
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144857145"
     variation       2790
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148173186"
     variation       2798
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987415"
     variation       2820
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146126278"
     variation       2854..2874
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="ggtctccaacccccgacctca"
                     /db_xref="dbSNP:199608526"
     variation       2860
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187256465"
     variation       2882
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10987416"
     variation       2883
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375078942"
     variation       2889
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:191584459"
     variation       2919
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144070517"
     variation       2932
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116411474"
     variation       2976
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183486611"
     variation       3003
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372210078"
     variation       3208..3213
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="ccccaa"
                     /replace="tcccag"
                     /db_xref="dbSNP:71494050"
     variation       3208
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34776870"
     variation       3211
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:74498940"
     variation       3213
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35632228"
     variation       3376
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145937520"
     variation       3400
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10733682"
     variation       3410..3411
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:149174535"
     variation       3561
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74429080"
     variation       3601
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:35712948"
     variation       3609
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10120414"
     variation       3610
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:10760451"
     variation       3647
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114971128"
     variation       3673
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188331536"
     variation       3679
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373410299"
     variation       3749
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376612764"
     variation       3797
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370880644"
     variation       3803
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374778359"
     variation       3805..3806
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:35559677"
     variation       3806
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77350418"
     variation       3807
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:57949927"
     variation       3929
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139482215"
     variation       3930
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149740102"
     variation       3955
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145602359"
     variation       4047
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148906444"
     variation       4182
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191951894"
     variation       4200
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4083644"
     variation       4398
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3861878"
     variation       4464
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145190620"
     variation       4558
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4083645"
     variation       4562
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7023938"
     variation       4770
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182607285"
     variation       4775
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376141195"
     variation       4932
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147614955"
     variation       4987
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:10987417"
     variation       5049
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987418"
     variation       5080
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:10987419"
     variation       5081
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987420"
     variation       5097
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:10987421"
     variation       5173
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:10987422"
     variation       5196
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:186932324"
     variation       5343
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146636393"
     variation       5345
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148294658"
     variation       5346
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140459665"
     variation       5373
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185290341"
     variation       5381
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:111940190"
     variation       5387
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3814119"
     variation       5426
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374547564"
     variation       5504
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150407176"
     variation       5589
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78565800"
     variation       5753
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78799000"
     polyA_signal    5777..5782
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
     variation       5786..5787
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35956748"
     polyA_site      5797
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
ORIGIN      

gcgtcccatggatatagcaacaggtcccgagtcgctggagaggtgcttccctcgcgggcagacggactgcgccaagatgttggacggcatcaagatggaggagcacgccctgcgccccgggcccgccactctgggggtgctgctgggctccgactgcccgcatcccgccgtctgcgagggctgccagcggcccatctccgaccgcttcctgatgcgagtcaacgagtcgtcctggcacgaggagtgtttgcagtgcgcggcgtgtcagcaagccctcaccaccagctgctacttccgggatcggaaactgtactgcaaacaagactaccaacagctcttcgcggccaagtgcagcggctgcatggagaagatcgcccccaccgagttcgtgatgcgggcgctggagtgcgtgtaccacctgggctgcttctgctgctgcgtgtgtgaacggcagctacgcaagggcgacgaattcgtgctcaaggagggccagctgctgtgcaagggtgactacgagaaggagaaggacctgctcagctccgtgagccccgacgagtccgactccgtgaagagcgaggatgaagatggggacatgaagccggccaaggggcagggcagtcagagcaagggcagcggggatgacgggaaggacccgcggaggcccaagcgaccccggaccatcctcaccacgcagcagcgaagagccttcaaggcctccttcgaggtctcgtcgaagccttgccgaaaggtccgagagacactggcagctgagacgggcctcagtgtgcgcgtggtccaggtctggtttcagaaccaaagagcaaagatgaagaagctggcgcggcggcaccagcagcagcaggagcagcagaactcccagcggctgggccaggaggtcctgtccagccgcatggagggcatgatggcttcctacacgccgctggccccaccacagcagcagatcgtggccatggaacagagcccctacggcagcagcgaccccttccagcagggcctcacgccgccccaaatgccaggtgaccacatgaacccctatgggaacgactccatcttccatgacatcgacagcgatacctccttaaccagcctcagcgactgcttcctcggctcctcagacgtgggctccctgcaggcccgcgtggggaaccccatcgaccggctctactccatgcagagttcctacttcgcctcctgagagccagccaggcgcacggacgcttgggcaggggcctgggggggactgccagcctctgcggccagcctggccacccccgccctgctctccgcacagactacagacagccatacggtgccctcccctcggccagctgggcctgaccactgtgcccgttgggtacagccagaccggtagatgggcacagcctgggcaggggctgtgtcctgcccacagagaccttgtcatccccagggacccagagctctcggacggccactcgcctcccagccccacctcggcctccatcgcctcctccccatctcttttttgggaagcttaaattctctctatttttttaaatgtcctctctgtgtccatggccctccatgcaagccccaggacaatggtgtcatgaggcggtgacctgagaagcgtgtgtacctgtgccccagcaagggcaggggtggcctctgggggcaggcccactgcctggaaccgcacacccctcagcctgagtctggagcagcagtggagaggggcctgaggggaggcactgtcaggaggcgggctcggagcctgagcctgggcaggcgcaaagggacagagaggcacgtgcagacacatgcacacttgcagacaaacccacgcaaacacacacacagctgtatggggacaccagaagggacagggatgctcagcgggtctgtcctgccttgtcagaaagagaaaaggaggccaggcaggggaccccccagttcttaagagcgattggaaagggaggaaggggagaggaagaggcgaacttgaagcatcggacccagttgtatcccagcctgggcccaaatgggggcagcctgggcagggagggcagccccaggccccaccaactctagaggcagatggagcccccagaaccaggtagcatcagaccagacaacagagcctccaggggtcagggacttcagaagcacctgctgggcaccccatctgcaatgtggtcctctccccagccacctctgcctcccctcacatacctccagtgacaaggagctcactaggtcagcgagcccacagcagctgtgctgtcctgcatcccagagccaggcttccccagctctccctcttaacactgtcccccagcaggcctccggctgtccctctaaaggtgtggggcaggtatcacttcaccttcccactgatgtcagccggccagaagtgagcaggcacatcacctctcctgctgtggcacccttcctctgttaatttggcccaaaagacaatgatttggccacatgaccttagagattcaccctgccctgctgtagctaaatccctgggccccacacgcaagtgacagctaagccacatctgttttctgtgtatatgcaggatgggggcacctactgttttgttttgttttgttttgttttgttttgttttgttttgttttgttttgtttgagacggagtttcgctcttgttgcccaggctggagtgcaatggcgcgatctcggctcaccacaacctccgcctcccaggttcaagtgattctgatgcctcagcctccctagtagctgagattacaggcatgcgccaccacacccagctaattttgtatttttagtagcaacggggtttctccatgttggtcaggctggtctccaacccccgacctcaggtgatccgcctgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcacccagtctgcacttactgtttagactgaatgagggaccgtgacctctttccttttccattccttcttactcgattcattccagcctgtggaatttctctgcaccctgattcagtgaccactgctctcctctctcccagcacatctgcccagtgaggagttggccctgggtctcacctgaggtgtgtggaccgggctggcctctccctgtttgacattggcccattaatgcatcctctttgggggacacattccaattgcatttcctgcccccttctcccagggcaattgcagaagattgtgtcaggcgccctgctggaagtcaggtgcactagatccatccccagccccagtctgctcaactctatccctgtcagagcaaggaggctgggctgctggggcctgactggtgagcccaccctgtcccctggtgatcactgtgtccccttgttcaggtgctcacaaccctacctttaactctgaggtcaagccctaggccaccaccctaaagtctgcctggtccaacctttgagcaagtaaggataatgaatgtcccttttccacctttggggccctctgcctggatctctggaatcctctaagttcaacctgttctgtggttttgctcccgtttgctgggaaattcagtccccccagaatgtcctgggccaacctccttgcctgacatgtggcctcgtgtcacccattgggccccagcagccagctagcccttctgcagctcttcttacaaacagagcctctccaaggacctcagttgatgttctggtccttctgccgcctcagcccaccagggtccgtgccaccatgggtctcttgagcagcagctgcactggcttctggagagacacccctctttctccttttgcacatgcaccatctgaatcgtgccagggacatcctgggcagattcaggggcagatgccctatcccccaggagacctggcccttctctctcagacccaataagttggaagggacgtcagaagcggtcatctcatctgccccttattttatagttggaaaccctgaggcaagagagggaaagaggcctgtccaaggtccgggttagtgacagagctgagctgagaacagggacgttgtgccccactgtcccctgtggtttgtgaatgacctccaggtcagggggtcacaacttgttcttagtaaacttgccagctgttggggtcacatattcccattctggggcctcacaaacccccgaatccagccgggaccccatgccaggagctggtctagggacagcatgcttgtgacccacagactgttaaagccagaagggacctcagagagtcccttatgctggaggcgccctgtcagccgtggctaggggccccttgctctatgctgtgccttgctgcccacaggctcccagacaccagtgcccactctgcccagccccggactgggtgtggctcgcagatgaacaagatgcagggcctgccttgaggggtgtctcctagaaggaaagccagactctccggcccagccagagagtccagacatggcagggacccgtttctcagatgaggagcctgaggctcagagaagggaggcgatgtgttcagggccacccagcagaagcctgtggggctgggcaaccttctcccactttatgggaggagctgcagccttggctgggagctgggcggggagtagccaggaccaccccttgcccgtgccgtgacatggaaccttcatcactaagggggctggagtgggaagagggagataactgtgtggtctccagagcaaaagagaatgagaggtgggcagggggagtcttggcaaaagaccaagttccacttccctgctggggaagtcaaggctcagaaagaggaaataattgccccaggtaacacagggcagaggagggacaaaaagctgggcatggccccagccagagcctcatctgcctactccgtgaagcctcccaggtactctgctatcctgggaaacgcacagggaggccacacagagacactgctcacaagagtcagaccaaggtgccagcacagcctggaaagagctcagaaagggggttggtgcacgtggctgggcatcttaggaggcttcctgagggtgggtaaaggtgggaaggccctggcgctgcatcagatgagcagggcctggcagggacaagcctcttctcctttgggaagccctgcagcctcctagcaagaggctgattccccactctgcccccatctgaatgtccttttcatgttgcacgcagggaacctcaggaaggaggattgcctgatgcctgcctggctccatccttgagctctgggcaccacctagggtgagggagagcctgcagctctggggctaagtctgccctggggggaaagggctccacgctcacacgcacgcgctcgcacacacacactcacacctggacgcacacggaggcttgcggacccatactcacaggcacatgtggcctggggactgggggagcaggaaagacccctccaacatttggcccttggaaggcaccattgccaatgagcctctttgctggttcccccgaccccacctgggggtcccatgggagcccagcccagccaggtgtggggatgggccaccggccattcctgttttccttgtacagacagattctcactacccacccgccatccccagacacattttatttaataacttgtcattgttaaattatttattagcgtttaccacaccaccacccccaccctgccctccactctcaccttccacctcttcccacaacagcagaaaatggaaacaacaacaaaaaaagatgagacatcagtatatttgtaaataaaccgacctgtacactcaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:4010 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
            GeneID:4010 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:4010 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
            GeneID:4010 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:4010 -> Biological process: GO:0001701 [in utero embryonic development] evidence: NAS
            GeneID:4010 -> Biological process: GO:0001764 [neuron migration] evidence: IEA
            GeneID:4010 -> Biological process: GO:0002930 [trabecular meshwork development] evidence: IEA
            GeneID:4010 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:4010 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IDA
            GeneID:4010 -> Biological process: GO:0007275 [multicellular organismal development] evidence: NAS
            GeneID:4010 -> Biological process: GO:0008219 [cell death] evidence: IEA
            GeneID:4010 -> Biological process: GO:0008283 [cell proliferation] evidence: IEA
            GeneID:4010 -> Biological process: GO:0009953 [dorsal/ventral pattern formation] evidence: ISS
            GeneID:4010 -> Biological process: GO:0021587 [cerebellum morphogenesis] evidence: IEA
            GeneID:4010 -> Biological process: GO:0021954 [central nervous system neuron development] evidence: IEA
            GeneID:4010 -> Biological process: GO:0030182 [neuron differentiation] evidence: ISS
            GeneID:4010 -> Biological process: GO:0030199 [collagen fibril organization] evidence: IEA
            GeneID:4010 -> Biological process: GO:0030901 [midbrain development] evidence: IEA
            GeneID:4010 -> Biological process: GO:0035108 [limb morphogenesis] evidence: IEA
            GeneID:4010 -> Biological process: GO:0035265 [organ growth] evidence: IEA
            GeneID:4010 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:4010 -> Biological process: GO:0071542 [dopaminergic neuron differentiation] evidence: IEA
            GeneID:4010 -> Cellular component: GO:0005634 [nucleus] evidence: IDA