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2024-04-16 21:01:36, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001135052 5010 bp mRNA linear PRI 15-JUL-2013
DEFINITION Homo sapiens spleen tyrosine kinase (SYK), transcript variant 2,
mRNA.
ACCESSION NM_001135052
VERSION NM_001135052.2 GI:293332513
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5010)
AUTHORS Yu,S., Huang,H., Iliuk,A., Wang,W.H., Jayasundera,K.B., Tao,W.A.,
Post,C.B. and Geahlen,R.L.
TITLE Syk inhibits the activity of protein kinase A by phosphorylating
tyrosine 330 of the catalytic subunit
JOURNAL J. Biol. Chem. 288 (15), 10870-10881 (2013)
PUBMED 23447535
REMARK GeneRIF: PKA is a novel substrate of Syk, and its phosphorylation
on Tyr-330 inhibits its participation in downstream signaling
pathways.
REFERENCE 2 (bases 1 to 5010)
AUTHORS Kim,Y., Kong,M. and Lee,C.
TITLE Association of intronic sequence variant in the gene encoding
spleen tyrosine kinase with susceptibility to vascular dementia
JOURNAL World J. Biol. Psychiatry 14 (3), 220-226 (2013)
PUBMED 23480133
REFERENCE 3 (bases 1 to 5010)
AUTHORS Vallieres,F. and Girard,D.
TITLE IL-21 enhances phagocytosis in mononuclear phagocyte cells:
identification of spleen tyrosine kinase as a novel molecular
target of IL-21
JOURNAL J. Immunol. 190 (6), 2904-2912 (2013)
PUBMED 23396946
REMARK GeneRIF: Spleen tyrosine kinase (Syk) is a novel and important
target of interleukin (IL)-21 for enhancing phagocytosis.
REFERENCE 4 (bases 1 to 5010)
AUTHORS Hussain,A., Mohammad,D.K., Gustafsson,M.O., Uslu,M., Hamasy,A.,
Nore,B.F., Mohamed,A.J. and Smith,C.I.
TITLE Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK
(spleen tyrosine kinase) fusion kinase is dependent on adapter
SLP-76 and on the adapter function of the kinases SYK and ZAP70
JOURNAL J. Biol. Chem. 288 (10), 7338-7350 (2013)
PUBMED 23293025
REMARK GeneRIF: Data indicate that the intracellular signaling of ITK-SYK
requires both SLP-76 and the adapter function of SYK/ZAP-70
kinases.
REFERENCE 5 (bases 1 to 5010)
AUTHORS Romero-Camarero,I., Jiang,X., Natkunam,Y., Lu,X.,
Vicente-Duenas,C., Gonzalez-Herrero,I., Flores,T., Garcia,J.L.,
McNamara,G., Kunder,C., Zhao,S., Segura,V., Fontan,L.,
Martinez-Climent,J.A., Garcia-Criado,F.J., Theis,J.D., Dogan,A.,
Campos-Sanchez,E., Green,M.R., Alizadeh,A.A., Cobaleda,C.,
Sanchez-Garcia,I. and Lossos,I.S.
TITLE Germinal centre protein HGAL promotes lymphoid hyperplasia and
amyloidosis via BCR-mediated Syk activation
JOURNAL Nat Commun 4, 1338 (2013)
PUBMED 23299888
REMARK GeneRIF: the germinal centre protein human germinal
centre-associated lymphoma regulates B-cell receptor signalling in
B-lymphocytes which, without appropriate control, may lead to
B-cell lymphoproliferation.
REFERENCE 6 (bases 1 to 5010)
AUTHORS Chan,A.C., Iwashima,M., Turck,C.W. and Weiss,A.
TITLE ZAP-70: a 70 kd protein-tyrosine kinase that associates with the
TCR zeta chain
JOURNAL Cell 71 (4), 649-662 (1992)
PUBMED 1423621
REFERENCE 7 (bases 1 to 5010)
AUTHORS Hutchcroft,J.E., Harrison,M.L. and Geahlen,R.L.
TITLE Association of the 72-kDa protein-tyrosine kinase PTK72 with the B
cell antigen receptor
JOURNAL J. Biol. Chem. 267 (12), 8613-8619 (1992)
PUBMED 1569106
REFERENCE 8 (bases 1 to 5010)
AUTHORS Yannoukakos,D., Meyer,H.E., Vasseur,C., Driancourt,C., Wajcman,H.
and Bursaux,E.
TITLE Three regions of erythrocyte band 3 protein are phosphorylated on
tyrosines: characterization of the phosphorylation sites by solid
phase sequencing combined with capillary electrophoresis
JOURNAL Biochim. Biophys. Acta 1066 (1), 70-76 (1991)
PUBMED 2065070
REFERENCE 9 (bases 1 to 5010)
AUTHORS Yannoukakos,D., Vasseur,C., Piau,J.P., Wajcman,H. and Bursaux,E.
TITLE Phosphorylation sites in human erythrocyte band 3 protein
JOURNAL Biochim. Biophys. Acta 1061 (2), 253-266 (1991)
PUBMED 1998697
REFERENCE 10 (bases 1 to 5010)
AUTHORS Kim,J.W., Sim,S.S., Kim,U.H., Nishibe,S., Wahl,M.I., Carpenter,G.
and Rhee,S.G.
TITLE Tyrosine residues in bovine phospholipase C-gamma phosphorylated by
the epidermal growth factor receptor in vitro
JOURNAL J. Biol. Chem. 265 (7), 3940-3943 (1990)
PUBMED 1689310
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB458719.1, Z29630.1,
AL354862.12 and W33104.1.
On Apr 2, 2010 this sequence version replaced gi:205277434.
Summary: This gene encodes a member of the family of non-receptor
type Tyr protein kinases. This protein is widely expressed in
hematopoietic cells and is involved in coupling activated
immunoreceptors to downstream signaling events that mediate diverse
cellular responses, including proliferation, differentiation, and
phagocytosis. It is thought to be a modulator of epithelial cell
growth and a potential tumour suppressor in human breast
carcinomas. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq, Mar 2010].
Transcript Variant: This variant (2) lacks an in-frame coding exon
compared to variant 1, resulting in a shorter isoform (2) missing
an internal protein segment compared to isoform 1. Variants 2 and 4
encode the same isoform.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: Z29630.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025088, ERS025089 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-57 DB458719.1 51-107
58-2591 Z29630.1 1-2534
2592-4868 AL354862.12 145228-147504
4869-5010 W33104.1 1-142 c
FEATURES Location/Qualifiers
source 1..5010
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q22"
gene 1..5010
/gene="SYK"
/gene_synonym="p72-Syk"
/note="spleen tyrosine kinase"
/db_xref="GeneID:6850"
/db_xref="HGNC:11491"
/db_xref="MIM:600085"
exon 1..164
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 69
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199721697"
variation 77
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200712879"
variation 92
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201472772"
variation 126
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199778155"
variation 145
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200900798"
variation 156
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:142604132"
variation 162
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199939971"
exon 165..622
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 177
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200237145"
variation 185
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201338526"
variation 193
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201341126"
variation 194
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200373424"
misc_feature 200..202
/gene="SYK"
/gene_synonym="p72-Syk"
/note="upstream in-frame stop codon"
CDS 206..2044
/gene="SYK"
/gene_synonym="p72-Syk"
/EC_number="2.7.10.2"
/note="isoform 2 is encoded by transcript variant 2;
tyrosine-protein kinase SYK"
/codon_start=1
/product="tyrosine-protein kinase SYK isoform 2"
/protein_id="NP_001128524.1"
/db_xref="GI:205277435"
/db_xref="CCDS:CCDS47992.1"
/db_xref="GeneID:6850"
/db_xref="HGNC:11491"
/db_xref="MIM:600085"
/translation="
MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPASSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
"
misc_feature 242..553
/gene="SYK"
/gene_synonym="p72-Syk"
/note="N-terminal Src homology 2 (SH2) domain found in
Zeta-chain-associated protein kinase 70 (ZAP-70) and
Spleen tyrosine kinase (Syk) proteins; Region:
SH2_N-SH2_Zap70_Syk_like; cd09938"
/db_xref="CDD:198191"
misc_feature order(269..271,329..331,392..394,398..400)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="phosphotyrosine binding pocket [polypeptide
binding]; other site"
/db_xref="CDD:198191"
misc_feature order(395..397,431..436,440..442,497..502)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="hydrophobic binding pocket [polypeptide binding];
other site"
/db_xref="CDD:198191"
misc_feature 695..991
/gene="SYK"
/gene_synonym="p72-Syk"
/note="C-terminal Src homology 2 (SH2) domain found in
Spleen tyrosine kinase (Syk) proteins; Region:
SH2_C-SH2_Syk_like; cd10401"
/db_xref="CDD:198264"
misc_feature order(728..730,788..790,794..796,848..850,854..856)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="phosphotyrosine binding pocket [polypeptide
binding]; other site"
/db_xref="CDD:198264"
misc_feature order(851..853,887..889,896..898,953..955)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="hydrophobic binding pocket [polypeptide binding];
other site"
/db_xref="CDD:198264"
misc_feature 1256..2014
/gene="SYK"
/gene_synonym="p72-Syk"
/note="Protein tyrosine kinase; Region: Pkinase_Tyr;
pfam07714"
/db_xref="CDD:203736"
misc_feature 1259..2029
/gene="SYK"
/gene_synonym="p72-Syk"
/note="Catalytic domain of the Protein Tyrosine Kinase,
Spleen tyrosine kinase; Region: PTKc_Syk; cd05116"
/db_xref="CDD:133247"
misc_feature order(1265..1279,1289..1291,1334..1336,1340..1342,
1433..1435,1478..1489,1496..1501,1616..1618,1628..1633,
1637..1639,1670..1672,1727..1741,1766..1768,1868..1870)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="active site"
/db_xref="CDD:133247"
misc_feature order(1265..1270,1289..1291,1334..1336,1340..1342,
1433..1435,1478..1489,1496..1501,1628..1633,1637..1639,
1667..1672)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:133247"
misc_feature order(1616..1618,1628..1630,1727..1741,1766..1768,
1868..1870)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:133247"
misc_feature 1667..1747
/gene="SYK"
/gene_synonym="p72-Syk"
/note="activation loop (A-loop); other site"
/db_xref="CDD:133247"
variation 209
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201301123"
variation 217
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199823436"
variation 218
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:146743944"
variation 222
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201350143"
variation 232
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201458538"
variation 233
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:199606629"
variation 256
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200626943"
variation 270
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:140421546"
variation 271
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139401525"
variation 286
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200577589"
variation 302
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201364101"
STS 306..530
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="STS-S80267"
/db_xref="UniSTS:70625"
variation 334
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:35758162"
variation 339
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:16906862"
variation 340
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201774526"
variation 352
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:140490837"
variation 358
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200928765"
variation 367
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:150440676"
variation 368
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200078199"
variation 376
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:371908826"
variation 397
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:138271353"
variation 399
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:149603234"
variation 417
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:146786995"
variation 420
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200175081"
variation 427
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:139316651"
variation 433
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202064642"
variation 436
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200362424"
variation 447
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201374653"
variation 456
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199818587"
variation 461
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201455170"
variation 464
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201177148"
variation 468
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:78791900"
variation 475
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199646361"
variation 495
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:200223184"
variation 516
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200453337"
variation 533
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202043759"
variation 534
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:375028044"
variation 541
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:143342183"
variation 615
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200097669"
variation 619
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:142980255"
exon 623..783
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 634
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199932327"
variation 637
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:370551918"
variation 644
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:373730562"
variation 679
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200921683"
variation 712
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:147347882"
variation 749
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200476529"
variation 775
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:148413110"
variation 778
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201529865"
exon 784..922
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 832
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202000893"
variation 850
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201867954"
variation 892
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199938327"
variation 893
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200498885"
variation 912
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201857010"
variation 913
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:200087795"
exon 923..1001
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 937
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201907766"
variation 942
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:184127752"
variation 964
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:34489331"
variation 980
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:201538038"
variation 989
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:112619650"
variation 992
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199886319"
exon 1002..1051
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1021
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201662709"
variation 1023
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139520862"
variation 1024
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:55920107"
variation 1027
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200859639"
variation 1049
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:377620701"
variation 1050
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201994789"
variation 1051
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199908671"
exon 1052..1139
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1057
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:146732805"
variation 1068
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199612745"
variation 1073
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200684262"
variation 1074
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201840933"
variation 1075
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:199745532"
variation 1102
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200697355"
variation 1122
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201358181"
exon 1140..1317
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1140
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139388374"
variation 1143
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200099811"
variation 1145
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:144168552"
variation 1149
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:56071116"
variation 1155
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200994798"
variation 1157
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200409467"
variation 1180
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:142936514"
variation 1192
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:41274652"
variation 1193
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200167353"
variation 1194
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201479078"
variation 1195
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:377587992"
variation 1201
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2290890"
variation 1211
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200418715"
variation 1217
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201460357"
variation 1236
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199772052"
variation 1243
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:376461830"
variation 1248
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:369986984"
variation 1249
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:151053124"
variation 1259
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201179887"
variation 1279
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="t"
/db_xref="dbSNP:67128367"
exon 1318..1527
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1330
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:375613854"
variation 1340
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:79190821"
variation 1354
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202093746"
STS 1369..1625
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="SYK-1"
/db_xref="UniSTS:513716"
variation 1370
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:201438493"
variation 1405
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200930117"
variation 1429
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:141000507"
variation 1432
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202166418"
variation 1438
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:2290888"
variation 1444
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201416422"
variation 1453
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202191431"
variation 1454
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200202947"
variation 1474
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:2290887"
variation 1492
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199712945"
variation 1501
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:143304676"
exon 1528..1717
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1545
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201930376"
variation 1561
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200072255"
variation 1567
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:56285406"
variation 1568
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201724218"
variation 1580
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200456955"
variation 1584
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:147125933"
variation 1621
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200991736"
variation 1633
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2306042"
variation 1657
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2306041"
variation 1663
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201341572"
variation 1666
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202069669"
variation 1669
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200251333"
variation 1675
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:34231418"
variation 1681
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2306040"
variation 1694
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200320837"
exon 1718..1858
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1729
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200628553"
variation 1746
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:371627100"
variation 1753
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201650753"
variation 1759
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201516360"
variation 1774
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201065688"
variation 1791
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199801793"
variation 1795
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:141667926"
variation 1846
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200957611"
variation 1857
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201765057"
exon 1859..1971
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1861
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201336985"
variation 1882
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:139024468"
variation 1883
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:369492720"
variation 1906
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:149469439"
variation 1943
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200438123"
variation 1969
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201360872"
exon 1972..5004
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
STS 1977..2724
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="SYK_1884"
/db_xref="UniSTS:281037"
variation 1987
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202024803"
variation 1988
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200612476"
variation 1993
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:374945682"
variation 1994
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139348511"
variation 1999
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:145685109"
variation 2017
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200834108"
variation 2019
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:150998279"
variation 2032
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201364356"
variation 2035
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200148300"
variation 2038
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200682995"
variation 2046
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201520390"
variation 2047
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199607948"
variation 2070
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201191948"
variation 2078
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201001425"
variation 2085
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202243160"
variation 2114
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200070739"
variation 2139
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201179148"
variation 2143
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202035242"
variation 2144
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:191082286"
variation 2161
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201474800"
variation 2178
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202088785"
variation 2225
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200443955"
variation 2232
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201367588"
variation 2233
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:113175204"
variation 2244
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200786369"
variation 2245
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201177252"
variation 2259
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:199644752"
variation 2264
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:56139234"
variation 2270
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:1804251"
variation 2284
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201615361"
variation 2293
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200080967"
variation 2309
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200817268"
variation 2310
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:182865904"
variation 2332
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:187420975"
variation 2365
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199888968"
variation 2366
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201168587"
variation 2368
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:1049164"
STS 2374..2514
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="WI-18899"
/db_xref="UniSTS:28988"
variation 2386
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199927091"
STS 2401..2530
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="RH69035"
/db_xref="UniSTS:21128"
variation 2435
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200937477"
variation 2459
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202179400"
variation 2461
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200478377"
variation 2464
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:41309340"
variation 2484
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201184094"
variation 2494
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202018238"
variation 2510
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:14979"
variation 2514
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:1804252"
variation 2517
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201236332"
variation 2518
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:41313849"
variation 2544..2545
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:34237652"
variation 2558
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:3087507"
polyA_signal 2560..2565
/gene="SYK"
/gene_synonym="p72-Syk"
variation 2566
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:113304691"
variation 2580
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201054834"
variation 2581
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:3087508"
variation 2587
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:3087506"
polyA_site 2591
/gene="SYK"
/gene_synonym="p72-Syk"
variation 2602
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199807708"
variation 2647..2648
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:113920845"
variation 2647
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200854897"
variation 2650
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:57651872"
variation 2651
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201993887"
variation 2680
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199584610"
variation 2682
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:113580142"
variation 2691
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201935229"
variation 2702
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200082519"
variation 2732
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200996064"
variation 2749
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:192822491"
variation 2758
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201640049"
variation 2761
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199893313"
variation 2762
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201228319"
variation 2777
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:202208832"
variation 2790
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200250756"
variation 2796
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200788246"
variation 2803
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201901573"
variation 2855
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200306296"
variation 2902
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:201170015"
variation 2903
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199593787"
variation 2909
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200233293"
variation 2931
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201530364"
variation 2941
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199757614"
variation 2948
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200639366"
variation 2956
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201656525"
variation 2957
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:140271666"
variation 2975
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200271297"
variation 2977
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201996237"
variation 2990
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:199910798"
variation 2991
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201033897"
variation 3003
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201904421"
variation 3009
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200062335"
variation 3016
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:158688"
variation 3035
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201766681"
variation 3050
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:184864847"
variation 3059
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201197144"
variation 3063
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202205240"
variation 3107
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:200418572"
variation 3108
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201475559"
variation 3109
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:376917555"
variation 3112
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202172624"
variation 3114
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:12344755"
variation 3140
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:158687"
variation 3171
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199614233"
variation 3173
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:74847439"
variation 3182
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:138070207"
variation 3196
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:10512203"
variation 3198
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:113367349"
variation 3234
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200684900"
variation 3236
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201846169"
variation 3241
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:158686"
variation 3242
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200678129"
variation 3244
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201507403"
variation 3260
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:199954919"
variation 3262
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201129087"
variation 3274
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202170530"
variation 3287
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200092376"
variation 3292
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201067892"
STS 3297..3385
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
variation 3299
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202049478"
variation 3306
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200169491"
variation 3307
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201483217"
variation 3308
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:202087399"
STS 3316..3426
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="D10S275"
/db_xref="UniSTS:147992"
variation 3324
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:192259837"
variation 3327
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201450125"
variation 3363
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199763889"
variation 3364
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200961449"
variation 3385
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201471258"
variation 3403
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199623121"
variation 3409
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200404562"
variation 3410
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:158685"
variation 3418
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200068159"
variation 3420
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200689319"
variation 3425
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:138672587"
variation 3440
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:183960220"
variation 3444
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:189425165"
variation 3457
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:142720783"
variation 3458
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199842566"
variation 3466
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201341496"
variation 3476
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201770050"
variation 3489
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199924149"
variation 3490..3494
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="aactt"
/db_xref="dbSNP:368223574"
variation 3490
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200933262"
variation 3492
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202178674"
variation 3497
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200488395"
variation 3569
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201111768"
variation 3570
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:5021552"
variation 3590
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202189825"
variation 3593
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:371047374"
variation 3594
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:115363876"
variation 3612
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:192548937"
variation 3615
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199783989"
variation 3624
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:184355645"
variation 3645
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201058837"
variation 3658
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:189146244"
variation 3670
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199768164"
variation 3683
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:181141508"
variation 3690
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201774920"
variation 3714
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:186279193"
variation 3720
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200592316"
variation 3728
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201934148"
variation 3746
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200079558"
variation 3758
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:112868894"
variation 3825
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201711043"
variation 3845
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199822713"
variation 3848
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201323598"
variation 3865
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202054985"
variation 3869
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200437396"
variation 3877
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:17568705"
variation 3878
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201899168"
variation 3894
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200311317"
variation 3912
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201177408"
variation 3916..3917
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:35758629"
variation 3931
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199604777"
variation 3942
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200219989"
variation 3958
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201716941"
variation 3964
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199714639"
variation 4010
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:148015317"
variation 4011
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200634194"
variation 4017
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201655256"
variation 4023
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199537078"
variation 4026
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:371399205"
variation 4028
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200782311"
variation 4038
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201768739"
variation 4049
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199976134"
variation 4079
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200655648"
variation 4107
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202076504"
variation 4115
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:10217275"
variation 4117
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200864082"
variation 4118
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:111798674"
variation 4131
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201771764"
variation 4134
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199911137"
variation 4138
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200984283"
variation 4143
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202058374"
variation 4147
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200440991"
variation 4172
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:115781501"
variation 4179
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202241782"
variation 4190
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200430210"
variation 4191
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201413796"
variation 4217
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199603436"
variation 4225
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200481350"
variation 4244
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201775735"
variation 4250
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199695443"
variation 4274
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200815743"
variation 4281
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:114553487"
variation 4290
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199914885"
variation 4296
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200680066"
variation 4306
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201514338"
variation 4320
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199958969"
variation 4353
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200795833"
variation 4367
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:73650275"
variation 4436
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:368631722"
variation 4437
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200073109"
variation 4445
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201185795"
variation 4447
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202006211"
variation 4471
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:13559"
variation 4473
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:72729087"
variation 4479
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201467820"
variation 4481
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202131391"
variation 4488
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200305022"
variation 4503
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201342619"
variation 4541
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199804824"
variation 4552
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200863208"
variation 4553
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201618755"
variation 4559
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199633431"
variation 4560
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:117866558"
variation 4562
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:201616726"
variation 4569
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:199774700"
variation 4574
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:141926409"
variation 4595
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201639704"
variation 4596
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199863553"
variation 4610
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201200597"
variation 4633
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201761264"
variation 4659
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199956562"
variation 4660
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200907814"
variation 4674
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202165739"
variation 4682
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200362937"
variation 4689
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201255894"
variation 4704
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202010594"
variation 4711
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200244210"
variation 4714
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201537770"
variation 4721
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:199792221"
variation 4725
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200278333"
variation 4728
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:189965276"
variation 4729
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199848843"
variation 4747
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200863059"
variation 4781
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:367775503"
STS 4785..4920
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="RH91425"
/db_xref="UniSTS:84312"
variation 4806
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201987311"
variation 4813
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199576591"
STS 4823..4956
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="D9S2062"
/db_xref="UniSTS:2175"
variation 4847
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:77417541"
variation 4869
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:8773"
variation 4909
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200056866"
variation 4933
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:150672706"
variation 4959
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:201710784"
variation 4962
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199868385"
variation 4965
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:201205439"
variation 4968
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202207011"
variation 4971
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200425328"
polyA_signal 4975..4980
/gene="SYK"
/gene_synonym="p72-Syk"
polyA_site 5004
/gene="SYK"
/gene_synonym="p72-Syk"
ORIGIN
acactgggaggaagtgcgggccgcctgcccgggcgcgttaaggaagttgcccaaaatgaggaagagccgcgggcccggcggctgaggccaccccggcggcggctggagagcgaggaggagcgggtggccccgcgctgcgcccgccctcgcctcacctggcgcaggtggacacctgcgcaggtgtgtgccctccggcccctgaagcatggccagcagcggcatggctgacagcgccaaccacctgcccttctttttcggcaacatcacccgggaggaggcagaagattacctggtccaggggggcatgagtgatgggctttatttgctgcgccagagccgcaactacctgggtggcttcgccctgtccgtggcccacgggaggaaggcacaccactacaccatcgagcgggagctgaatggcacctacgccatcgccggtggcaggacccatgccagccccgccgacctctgccactaccactcccaggagtctgatggcctggtctgcctcctcaagaagcccttcaaccggccccaaggggtgcagcccaagactgggccctttgaggatttgaaggaaaacctcatcagggaatatgtgaagcagacatggaacctgcagggtcaggctctggagcaggccatcatcagtcagaagcctcagctggagaagctgatcgctaccacagcccatgaaaaaatgccttggttccatggaaaaatctctcgggaagaatctgagcaaattgtcctgataggatcaaagacaaatggaaagttcctgatccgagccagagacaacaacggctcctacgccctgtgcctgctgcacgaagggaaggtgctgcactatcgcatcgacaaagacaagacagggaagctctccatccccgagggaaagaagttcgacacgctctggcagctagtcgagcattattcttataaagcagatggtttgttaagagttcttactgtcccatgtcaaaaaatcggcacacagggaaatgttaattttggaggccgtccacaacttccaggttcccatcctgcgtcctcccctgcccaagggaaccggcaagagagtactgtgtcattcaatccgtatgagccagaacttgcaccctgggctgcagacaaaggcccccagagagaagccctacccatggacacagaggtgtacgagagcccctacgcggaccccgaggagatcaggcccaaggaggtttacctggaccgaaagctgctgacgctggaagacaaagaactgggctctggtaattttggaactgtgaaaaagggctactaccaaatgaaaaaagttgtgaaaaccgtggctgtgaaaatactgaaaaacgaggccaatgaccccgctcttaaagatgagttattagcagaagcaaatgtcatgcagcagctggacaacccgtacatcgtgcggatgatcgggatatgcgaggccgagtcctggatgctggttatggagatggcagaacttggtcccctcaataagtatttgcagcagaacagacatgtcaaggataagaacatcatagaactggttcatcaggtttccatgggcatgaagtacttggaggagagcaattttgtgcacagagatctggctgcaagaaatgtgttgctagttacccaacattacgccaagatcagtgatttcggactttccaaagcactgcgtgctgatgaaaactactacaaggcccagacccatggaaagtggcctgtcaagtggtacgctccggaatgcatcaactactacaagttctccagcaaaagcgatgtctggagctttggagtgttgatgtgggaagcattctcctatgggcagaagccatatcgagggatgaaaggaagtgaagtcaccgctatgttagagaaaggagagcggatggggtgccctgcagggtgtccaagagagatgtacgatctcatgaatctgtgctggacatacgatgtggaaaacaggcccggattcgcagcagtggaactgcggctgcgcaattactactatgacgtggtgaactaaccgctcccgcacctgtcggtggctgcctttgatcacaggagcaatcacaggaaaatgtatccagaggaattgattgtcagccacctccctctgccagtcgggagagccaggcttggatggaacatgcccacaacttgtcacccaaagcctgtcccaggactcaccctccacaaagcaaaggcagtcccgggagaaaagacggatggcaggatccaaggggctagctggatttgtttgttttcttgtctgtgtgattttcatacaggttatttttacgatctgtttccaaatccctttcatgtctttccacttctctgggtcccggggtgcatttgttactcatcgggcccagggacattgcagagtggcctagagcactctcaccccaagcggccttttccaaatgcccaaggatgccttagcatgtgactcctgaagggaaggcaaaggcagaggaatttggctgcttctacggccatgagactgatccctggccactgaaaagctttcctgacaataaaaatgttttgaggctttaaaaagaaaatcaagtttgaccagtgcagtttctaagcatgtagccagttaaggaaagaaagaaagaaaaaaaaaaaaggcctggatactgcttttgctgtctctgttatgagatggaagacttacatgtttgtgataaaaggggaccatgagaatgaattggcttggcttactttccccctgaaatcctctctcctgcagactgtcttgaagacctggtgactggtaaataaagccctgcatggaggctgcacagcaggggcaagaggcccatcccccagcatctcactgaggacagcttcaggctgccttcctctgaacgtggtccacaccttcctctcctccacagagagggtgccgccagaatcccctgtcgctttctgtgtctgcaatggggggcagcacagggatcaaagccatctaaagagtttccaaagaaagtattaattcagaacaagccaaagaccctgagcctcaccacaaacaggccttttggagtgtgaatttgagttgaagatacaagatcggagaatgattttctggtcttaactaatcctcatcttcatgtttgatctttaagaagtcatcacccattgatttcagttttgctgtacctcttgaaagttaaagagacatctcagcactttaggaggccgaggcgggtggatcacttgaggtaaggagtttgagactagcctggccaatatggtaaaaccccatctctactaaaaatacaaaaattagccgggcatggtggcatgtgtctgtagtcccagctactcgggaggctgaggcaggagaatcgcttgaacccaggaaacggaggtcgcagtgagccaagatcatgccactgcactccagcttgggcatcacagcgagactctgtcaaaacaaacaaacaaaaaaacaacttaaagaggtaatttagccatcattcttatgccagcagatataaataaacttggacccatctggtcttcagctaaacctgagacattttaaagtgcatggacagccatggacagcaggccctcctctaacaggggatgcaaggcatggagaaagacaatcagtacccaagctcagccacagaagacaggagtcactcatataacttgtgtttagaagtttttggtagccacgcacactttctgaaatcacactatctggtggtttaatcatatttttaaagacagaatccctgagtgctgagcagattctcaaaacacatttagaatccctgaaattagaaagatcaatgacaaaatatctgtcagccaggccacaaacaggtgtaaaattatgaaaggagtggttggatgtgccaagtttggtaaagtggtgactgcatctgagaaagaggctgtgaggctgaactcttggtggcttccttctgtaacttccagagggagtcttcaacacaggccccgtgctcgtaggaatacggtagcacctatgtaggaagtgcgtggagttttctgtcttctttctgtgtgatttttggcctttttatcagcacttctcccctcccaggagcctggggatgccaaacatccagaatgtgatgggacaagatgggggcaggggcctcacctccctgcagaggtccggccaggtctccttgtccctggacaatctcctgagcctctctgcttggtggagcaggcacctgtgtgcagaattcccactgtggccagcacgaggaagtcttttctagtgaaaatgtgtcttgtggtcaggaataattatcctttcccctgtagccaccaaggagggcaaatagagaaaggtaacctaattgaaggattggtcatgtgaaaagggctacatttgggaagctgggaaaggcctccaggcttctagagcagctagcttgggctggattctcatacccaggctgccccttggattgttctacccaagcttttccctggggtctgggctcactccataaggtaaggtgccttttaccttatggtccttctttagcaggtaacaaaggagcatcaggggcaggctgccctggtggcatcacactggctagtgaggccgtgaatatcttgtcccccagcagggccgacagtttctatcacagaaaacagtgtgttcagtggtgaaaatcgttgcatgcatgttttcatctgagcgtgtccttctcccatactccctatcagccagccctgcctgtagctgctgtatggtgattgcacttggacatcagtccaatgactgcaagtcggcctggattttcacttgcagaggctacagctgcattgtcaggtctcccagccctgcagagagctccctccactggttagcagtgtgttgtgttttccattcatttcagaagagctacattgtgtcactggacatttttaaaaactgtgatttttaataaaaatttaaaatttgctttgtgatgaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:6850 -> Molecular function: GO:0004672 [protein kinase activity] evidence: NAS
GeneID:6850 -> Molecular function: GO:0004713 [protein tyrosine kinase activity] evidence: EXP
GeneID:6850 -> Molecular function: GO:0004713 [protein tyrosine kinase activity] evidence: TAS
GeneID:6850 -> Molecular function: GO:0004715 [non-membrane spanning protein tyrosine kinase activity] evidence: IDA
GeneID:6850 -> Molecular function: GO:0004715 [non-membrane spanning protein tyrosine kinase activity] evidence: TAS
GeneID:6850 -> Molecular function: GO:0004716 [receptor signaling protein tyrosine kinase activity] evidence: IEA
GeneID:6850 -> Molecular function: GO:0005178 [integrin binding] evidence: IPI
GeneID:6850 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:6850 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:6850 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
GeneID:6850 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA
GeneID:6850 -> Biological process: GO:0001945 [lymph vessel development] evidence: ISS
GeneID:6850 -> Biological process: GO:0002250 [adaptive immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002281 [macrophage activation involved in immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002283 [neutrophil activation involved in immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002366 [leukocyte activation involved in immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002554 [serotonin secretion by platelet] evidence: ISS
GeneID:6850 -> Biological process: GO:0006468 [protein phosphorylation] evidence: ISS
GeneID:6850 -> Biological process: GO:0007159 [leukocyte cell-cell adhesion] evidence: IDA
GeneID:6850 -> Biological process: GO:0007167 [enzyme linked receptor protein signaling pathway] evidence: IEA
GeneID:6850 -> Biological process: GO:0007229 [integrin-mediated signaling pathway] evidence: ISS
GeneID:6850 -> Biological process: GO:0007229 [integrin-mediated signaling pathway] evidence: NAS
GeneID:6850 -> Biological process: GO:0007257 [activation of JUN kinase activity] evidence: IEA
GeneID:6850 -> Biological process: GO:0007596 [blood coagulation] evidence: TAS
GeneID:6850 -> Biological process: GO:0008283 [cell proliferation] evidence: TAS
GeneID:6850 -> Biological process: GO:0009887 [organ morphogenesis] evidence: TAS
GeneID:6850 -> Biological process: GO:0010543 [regulation of platelet activation] evidence: ISS
GeneID:6850 -> Biological process: GO:0018108 [peptidyl-tyrosine phosphorylation] evidence: IEA
GeneID:6850 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
GeneID:6850 -> Biological process: GO:0019370 [leukotriene biosynthetic process] evidence: IEA
GeneID:6850 -> Biological process: GO:0030168 [platelet activation] evidence: TAS
GeneID:6850 -> Biological process: GO:0030593 [neutrophil chemotaxis] evidence: IDA
GeneID:6850 -> Biological process: GO:0032928 [regulation of superoxide anion generation] evidence: ISS
GeneID:6850 -> Biological process: GO:0033630 [positive regulation of cell adhesion mediated by integrin] evidence: ISS
GeneID:6850 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:6850 -> Biological process: GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] evidence: TAS
GeneID:6850 -> Biological process: GO:0042742 [defense response to bacterium] evidence: ISS
GeneID:6850 -> Biological process: GO:0043306 [positive regulation of mast cell degranulation] evidence: IEA
GeneID:6850 -> Biological process: GO:0043313 [regulation of neutrophil degranulation] evidence: ISS
GeneID:6850 -> Biological process: GO:0043366 [beta selection] evidence: IEA
GeneID:6850 -> Biological process: GO:0045087 [innate immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:6850 -> Biological process: GO:0045401 [positive regulation of interleukin-3 biosynthetic process] evidence: IEA
GeneID:6850 -> Biological process: GO:0045425 [positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process] evidence: IEA
GeneID:6850 -> Biological process: GO:0045579 [positive regulation of B cell differentiation] evidence: IEA
GeneID:6850 -> Biological process: GO:0045588 [positive regulation of gamma-delta T cell differentiation] evidence: IEA
GeneID:6850 -> Biological process: GO:0045780 [positive regulation of bone resorption] evidence: ISS
GeneID:6850 -> Biological process: GO:0046638 [positive regulation of alpha-beta T cell differentiation] evidence: IEA
GeneID:6850 -> Biological process: GO:0046641 [positive regulation of alpha-beta T cell proliferation] evidence: IEA
GeneID:6850 -> Biological process: GO:0046777 [protein autophosphorylation] evidence: IEA
GeneID:6850 -> Biological process: GO:0048514 [blood vessel morphogenesis] evidence: ISS
GeneID:6850 -> Biological process: GO:0050715 [positive regulation of cytokine secretion] evidence: IEA
GeneID:6850 -> Biological process: GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] evidence: IEA
GeneID:6850 -> Biological process: GO:0050764 [regulation of phagocytosis] evidence: ISS
GeneID:6850 -> Biological process: GO:0050850 [positive regulation of calcium-mediated signaling] evidence: IEA
GeneID:6850 -> Biological process: GO:0050853 [B cell receptor signaling pathway] evidence: ISS
GeneID:6850 -> Biological process: GO:0070372 [regulation of ERK1 and ERK2 cascade] evidence: ISS
GeneID:6850 -> Biological process: GO:0071226 [cellular response to molecule of fungal origin] evidence: ISS
GeneID:6850 -> Biological process: GO:0090237 [regulation of arachidonic acid secretion] evidence: ISS
GeneID:6850 -> Biological process: GO:0090330 [regulation of platelet aggregation] evidence: ISS
GeneID:6850 -> Cellular component: GO:0005829 [cytosol] evidence: IC
GeneID:6850 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:6850 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:6850 -> Cellular component: GO:0019815 [B cell receptor complex] evidence: IEA
GeneID:6850 -> Cellular component: GO:0032009 [early phagosome] evidence: ISS
GeneID:6850 -> Cellular component: GO:0042101 [T cell receptor complex] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_001128524 -> EC 2.7.10.2
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.