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2025-05-09 18:38:27, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_018003 6873 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens uveal autoantigen with coiled-coil domains and ankyrin
repeats (UACA), transcript variant 1, mRNA.
ACCESSION NM_018003
VERSION NM_018003.2 GI:59850761
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6873)
AUTHORS Moravcikova,E., Krepela,E., Prochazka,J., Rousalova,I., Cermak,J.
and Benkova,K.
TITLE Down-regulated expression of apoptosis-associated genes APIP and
UACA in non-small cell lung carcinoma
JOURNAL Int. J. Oncol. 40 (6), 2111-2121 (2012)
PUBMED 22407486
REMARK GeneRIF: The down-regulation of APIP and UACA expression suggests
that the threshold to activate the apoptosome apparatus may be
decreased in non-small cell lung cancer cells.
REFERENCE 2 (bases 1 to 6873)
AUTHORS Trynka,G., Zhernakova,A., Romanos,J., Franke,L., Hunt,K.A.,
Turner,G., Bruinenberg,M., Heap,G.A., Platteel,M., Ryan,A.W., de
Kovel,C., Holmes,G.K., Howdle,P.D., Walters,J.R., Sanders,D.S.,
Mulder,C.J., Mearin,M.L., Verbeek,W.H., Trimble,V., Stevens,F.M.,
Kelleher,D., Barisani,D., Bardella,M.T., McManus,R., van Heel,D.A.
and Wijmenga,C.
TITLE Coeliac disease-associated risk variants in TNFAIP3 and REL
implicate altered NF-kappaB signalling
JOURNAL Gut 58 (8), 1078-1083 (2009)
PUBMED 19240061
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 6873)
AUTHORS Cockman,M.E., Lancaster,D.E., Stolze,I.P., Hewitson,K.S.,
McDonough,M.A., Coleman,M.L., Coles,C.H., Yu,X., Hay,R.T.,
Ley,S.C., Pugh,C.W., Oldham,N.J., Masson,N., Schofield,C.J. and
Ratcliffe,P.J.
TITLE Posttranslational hydroxylation of ankyrin repeats in IkappaB
proteins by the hypoxia-inducible factor (HIF) asparaginyl
hydroxylase, factor inhibiting HIF (FIH)
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 103 (40), 14767-14772 (2006)
PUBMED 17003112
REFERENCE 4 (bases 1 to 6873)
AUTHORS Ohkura,T., Taniguchi,S., Yamada,K., Nishio,N., Okamura,T.,
Yoshida,A., Kamijou,K., Fukata,S., Kuma,K., Inoue,Y., Hisatome,I.,
Senju,S., Nishimura,Y. and Shigemasa,C.
TITLE Detection of the novel autoantibody (anti-UACA antibody) in
patients with Graves' disease
JOURNAL Biochem. Biophys. Res. Commun. 321 (2), 432-440 (2004)
PUBMED 15358194
REMARK GeneRIF: UACA is a novel candidate for eye muscle autoantigens in
thyroid-associated ophthalmopathy
REFERENCE 5 (bases 1 to 6873)
AUTHORS Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
TITLE Large-scale characterization of HeLa cell nuclear phosphoproteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
PUBMED 15302935
REFERENCE 6 (bases 1 to 6873)
AUTHORS Yamada,K., Senju,S., Nakatsura,T., Murata,Y., Ishihara,M.,
Nakamura,S., Ohno,S., Negi,A. and Nishimura,Y.
TITLE Identification of a novel autoantigen UACA in patients with
panuveitis
JOURNAL Biochem. Biophys. Res. Commun. 280 (4), 1169-1176 (2001)
PUBMED 11162650
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
CN303461.1, AF322916.1, AB046781.2, BM693348.1, AC087699.11 and
BU736944.1.
On Feb 15, 2005 this sequence version replaced gi:24308154.
Transcript Variant: This variant (1) represents the shorter
transcript but encodes the longer isoform (1).
##Evidence-Data-START##
Transcript exon combination :: AB046781.2, BC113409.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-55 CN303461.1 2-56
56-520 AF322916.1 1-465
521-3058 AB046781.2 417-2954
3059-3334 BM693348.1 212-487
3335-4477 AB046781.2 3231-4373
4478-6294 AC087699.11 115182-116998 c
6295-6873 BU736944.1 1-579 c
FEATURES Location/Qualifiers
source 1..6873
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q22-q24"
gene 1..6873
/gene="UACA"
/gene_synonym="NUCLING"
/note="uveal autoantigen with coiled-coil domains and
ankyrin repeats"
/db_xref="GeneID:55075"
/db_xref="HGNC:15947"
/db_xref="MIM:612516"
exon 1..182
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
CDS 105..4355
/gene="UACA"
/gene_synonym="NUCLING"
/note="isoform 1 is encoded by transcript variant 1;
nuclear membrane binding protein; uveal autoantigen with
coiled coil domains and ankyrin repeats"
/codon_start=1
/product="uveal autoantigen with coiled-coil domains and
ankyrin repeats isoform 1"
/protein_id="NP_060473.2"
/db_xref="GI:59850762"
/db_xref="CCDS:CCDS10235.1"
/db_xref="GeneID:55075"
/db_xref="HGNC:15947"
/db_xref="MIM:612516"
/translation="
MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
"
misc_feature 216..563
/gene="UACA"
/gene_synonym="NUCLING"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 216..479
/gene="UACA"
/gene_synonym="NUCLING"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 216..302
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
Region: ANK 1"
misc_feature 303..392
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
Region: ANK 2"
misc_feature 396..764
/gene="UACA"
/gene_synonym="NUCLING"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 402..491
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
Region: ANK 3"
misc_feature 417..695
/gene="UACA"
/gene_synonym="NUCLING"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 501..590
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
Region: ANK 4"
misc_feature 600..689
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
Region: ANK 5"
misc_feature 615..860
/gene="UACA"
/gene_synonym="NUCLING"
/note="Ankyrin repeats (3 copies); Region: Ank_2;
pfam12796"
/db_xref="CDD:205076"
misc_feature 684..>887
/gene="UACA"
/gene_synonym="NUCLING"
/note="ankyrin repeats; ankyrin repeats mediate
protein-protein interactions in very diverse families of
proteins. The number of ANK repeats in a protein can range
from 2 to over 20 (ankyrins, for example). ANK repeats may
occur in combinations with other...; Region: ANK; cd00204"
/db_xref="CDD:29261"
misc_feature 699..788
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZF9.2);
Region: ANK 6"
misc_feature 1824..4259
/gene="UACA"
/gene_synonym="NUCLING"
/note="Chromosome segregation ATPases [Cell division and
chromosome partitioning]; Region: Smc; COG1196"
/db_xref="CDD:31389"
misc_feature 2271..2273
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2505..2507
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3297..3299
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/citation=[5]
exon 183..316
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 317..405
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 406..470
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 471..528
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 529..599
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 600..706
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 707..888
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 889..926
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 927..995
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 996..1103
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1104..1136
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1137..1235
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1236..1272
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1273..1325
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 1326..4064
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
STS 3445..3611
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="SHGC-56623"
/db_xref="UniSTS:19628"
variation 3746
/gene="UACA"
/gene_synonym="NUCLING"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1056326"
exon 4065..4217
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 4218..4283
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
exon 4284..6857
/gene="UACA"
/gene_synonym="NUCLING"
/inference="alignment:Splign:1.39.8"
STS 4291..4438
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="D15S1354"
/db_xref="UniSTS:4637"
polyA_signal 4453..4458
/gene="UACA"
/gene_synonym="NUCLING"
polyA_signal 4458..4463
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 4478
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
polyA_signal 4928..4933
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 4947
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
variation 5632
/gene="UACA"
/gene_synonym="NUCLING"
/replace=""
/replace="c"
/db_xref="dbSNP:71152306"
STS 5910..5942
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="GDB:335751"
/db_xref="UniSTS:156601"
STS 5992..6080
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 6042..6111
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="D1S1423"
/db_xref="UniSTS:149619"
polyA_signal 6287..6292
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 6305
/gene="UACA"
/gene_synonym="NUCLING"
/experiment="experimental evidence, no additional details
recorded"
STS 6631..6784
/gene="UACA"
/gene_synonym="NUCLING"
/standard_name="RH98418"
/db_xref="UniSTS:91735"
variation 6777
/gene="UACA"
/gene_synonym="NUCLING"
/replace="c"
/replace="g"
/db_xref="dbSNP:720519"
polyA_signal 6831..6836
/gene="UACA"
/gene_synonym="NUCLING"
polyA_site 6857
/gene="UACA"
/gene_synonym="NUCLING"
ORIGIN
ggtacagcccgcgccgcctctgctgcagccgctgccgtctactccttgcgcgctggcactccgcagcctttaaggttcgcgcgggggccaggcaagagttagccatgaagagcctcaagtcccgcctgaggaggcaggacgtgcccggccccgcgtcgtctggcgccgccgccgccagcgcgcatgcagcagattggaataaatatgatgaccgattgatgaaagcagcagaaaggggggatgtagaaaaagtgacctcaatccttgctaaaaagggggtcaatccaggcaaactagatgtggaaggcagatctgtcttccatgttgtgacctcaaaggggaatcttgagtgtttgaatgccatccttatacatggagttgatattacaaccagtgacactgcagggagaaatgctcttcacctggctgctaagtatggacatgcattgtgcctacaaaaacttctacagtacaattgtcccactgagcatgcagacctgcagggaagaactgcacttcacgatgccgcaatggcagattgtccttctagcatacagctgctttgtgaccatggggcctctgtgaatgccaaagatgtagacgggcggacaccacttgttctggctactcagatgagtaggccaacaatatgtcaactgctgatagatagaggagcggatgttaattccagagacaaacaaaacagaactgccctcatgctaggttgcgaatatggttgcagagatgcagtagaagtcttaattaaaaatggtgctgatataagcttgctggatgcgcttggccatgatagttcttactatgcaagaattggtgacaatctggacattctaaccttgttgaagactgcatcggaaaataccaacaaagggagagaactttggaagaaagggccatctttgcaacagcgaaatttgacacacatgcaagatgaagtaaatgtgaagtcacatcagagggagcatcaaaatattcaggatttggagattgaaaatgaagatttgaaagagaggttgagaaaaattcagcaagaacaaagaatacttttggataaagtcaatggtttacagttacagctgaatgaggaagttatggttgctgatgatctggaaagcgagagagaaaagctgaagtcccttttggcagctaaagaaaagcaacatgaagaaagcttaaggactattgaggctctgaaaaatagatttaaatattttgagagtgatcatttaggatcaggaagtcatttcagtaaccgaaaagaagatatgcttcttaaacaaggtcagatgtatatggcagactcacagtgtacttccccaggtataccagcccatatgcaaagcagatctatgttaagacctctggaactatctttacccagtcaaacgtcatactctgaaaatgaaattttaaagaaagagttagaagcaatgcgaactttctgtgagtcagcaaaacaagaccgactgaagctccaaaatgaactggcacacaaagtggcagaatgcaaagctttagcattagaatgtgaaagggtcaaggaggattcagatgaacagataaagcaattagaagatgcattaaaagatgtgcagaagaggatgtatgagtcagaaggtaaagttaaacaaatgcagacccattttcttgcccttaaagaacacttaacaagtgaagcagcctcagggaatcacagactaaccgaggaactgaaggatcagttgaaagacttgaaagtaaaatatgaaggtgcttcagcagaagtggggaaattaagaaaccaaatcaaacaaaatgagatgatagtagaagagtttaagagggatgaaggcaagctgatagaagaaaataagcgattacagaaggaacttagtatgtgtgaaatggagcgagagaagaaaggaagaaaggtcacagagatggaaggccaggcaaaagaattgtcagcgaagttggccctttccattccagctgaaaaatttgaaaacatgaagagctcattatcaaatgaagtgaatgagaaagcaaaaaaattagtagaaatggaaagagaacatgaaaaatcacttagtgaaattagacagttaaagagagaacttgagaatgttaaggccaagcttgctcagcacgtcaaaccagaggaacatgaacaggttaagagcagattagaacagaaatcaggagaacttgggaagaagatcactgagttaacattgaaaaatcagacactacaaaaggaaattgaaaaagtttatttggataataagctcctcaaggagcaagcacataacttaacaattgaaatgaaaaatcattatgttcctttaaaagtaagtgaagacatgaaaaagtcacatgatgcaattattgatgatcttaatagaaagcttttagatgtaacacaaaaatatacagaaaagaagttggaaatggagaaattgctactggaaaatgacagcttaagtaaggatgtaagccgcctagaaactgtgtttgtacctcctgagaaacatgaaaaagagataatagctctgaaatccaatattgttgaacttaagaaacagctgtctgaacttaagaaaaaatgtggtgaagaccaggagaaaatacacgctctcacatctgaaaacactaacttgaagaagatgatgagtaatcagtatgtgccagttaaaacccatgaagaggttaaaatgacactgaatgacacgttagccaaaactaacagagaattattagatgtgaagaaaaaatttgaagatataaatcaggaatttgtaaaaataaaagataagaatgaaatattaaaaagaaacctggaaaacactcagaaccaaataaaagctgagtacatcagcctggcagagcacgaggcaaagatgagctcgctaagtcagagcatgagaaaggtgcaggatagtaatgctgaaatcttggccaactacagaaaaggccaagaagagattgtgacactgcatgccgaaattaaagcccagaagaaggagctcgacacaatacaagaatgcattaaggtaaaatacgccccaattgtcagctttgaggagtgcgagagaaaatttaaagcaacagagaaagaactaaaagaccagttatcagagcagacacaaaagtatagtgtcagtgaagaagaagtcaagaaaaacaagcaagagaatgacaagttaaagaaggagatttttacccttcagaaagatttgagagataagacagttctcattgagaagtctcatgaaatggaaagagcattaagcagaaaaacagacgagctaaacaaacagttaaaagacttgtcacagaaatacacggaagtaaagaatgtgaaagagaagctagtagaagaaaatgccaaacagacttctgagatacttgcagtgcaaaatcttttgcaaaaacaacatgttccattggaacaggttgaggctctgaaaaaatctcttaatggcacaattgaaaatctaaaggaagaactgaagagtatgcaaaggtgttacgagaaagagcagcagacagtgaccaaactgcatcaattgttggagaatcaaaagaactcttctgtacccctggcagagcatttgcagattaaagaagcatttgagaaagaagttggaatcataaaagccagcttgagagaaaaggaagaagaaagccaaaacaaaatggaagaagtctccaaacttcagtcggaggttcagaatactaaacaagcattaaaaaaattagagactagagaggtagttgacttgtctaaatataaagcaacaaaaagtgatttggagacacagatttctagcttaaatgaaaaattggccaatctgaatagaaagtatgaggaagtatgtgaggaagttttgcatgccaaaaagaaggaaatatctgcaaaagatgagaaggaattactgcatttcagcattgagcaagaaattaaggatcagaaggaacgatgtgataagtccttaacaacaatcacagagttacaaagaagaatacaagaatctgctaaacaaatagaagcaaaagataataagataactgaactgcttaatgatgtggaaagattaaaacaggcactcaatggcctttcccaactcacctacacaagtgggaaccccaccaagaggcagagccagctgattgacactctgcagcaccaagtgaaatctctggagcaacagctggccgatgctgacagacagcaccaagaagtaattgcaatttatcggacacaccttcttagtgctgcacagggtcacatggatgaagatgttcaggaggctctgctccagatcatacaaatgcggcaggggcttgtgtgctagccgttagcactgactgccagtatctgttttatcttgctggtgctgaacattctttgtgcaactccatggtctttctgggccttactgtgctggtataattaaaataaaatatattttgttctattggtaggtttttttttaaaattagatgaatatgttagtctttttcaatatcagtttgaatcttattttctgtatgtgttaattttacaaataggcaaacaacataactttgccctggattgactacatatttttaaaccttcaagtccctaataaaacatgagccatctgagtgagtccatatgaagcgaggttaggctgaaataattgcttaaagatgtctttcagagaaattaatttggttggtggccacttttaggtggatcaaaagacctttcagatcctcagaaccttgagacataatacagttgtgaggaatgtgttgtaacttggctggccaagttacatgttacagtatctttactgaggtaacttcattagtgtctttggccttttttgtaggtatagatattttttctttttacactaataacttttatgccttttaaaataaatttattttcataaatggtttgcagtgctaaattacatttagattaagaacaggcaggggtggaatatatcaggaatttataataaaattgccttaatctctacaacagtatcttaatttttacttgcggtgactattcttgccacaatattggagaataatgatagatgatatactagatttttcaaagtgtgaaaacctttagactttttttagcaattagtttgacattcgctactatagtaaccaagcactcattatatatgcatcctccaaatgtttcatgcttatttataggaaagttatattaatgagattaataatgtgaaatacagttttcctgcaaaattagcattagagaattgattttagataacagatttttaaagttttagagaaaagtacagtaatacagtaaactgaaagagtatatagatagcaataaaataacataagtggacatgtttatagtaaatactctgaagtaaacaaccgtttttattaactgcatctcattagggaaagtttatatgtcttgttattttttattaacattttatttaccattcagagtgaaaattactaatttgagtattaacaaataactgaataaatggatcattacagttaggttttctcaaattgcaaaatttgccttagcaattatctttgaacatcccgaaccagatttttaaatcccatttttgtttaatagggtaaaaataccatcaaaatgacttctcataccaaagaataagccatcatattttttcggtgttgaaacaacattgaaagtcagaattggatttgtttttaattctttatacggtttacataagcaatatctgtctctttaattattatgattaatgtcgtccttcagcatgagttctgtttcacaagttttgggccacctatttcaataaaaaataaaatataaattaaaaaagttgccgggggtggtggctcatgcctgtaatcccagcactttgggaggctgagggaggtagatcacctgaggtcagaagttcgagaccagccttaccaatatggtgaagccccatctctactaaaaatacaaaaattagccctgcatggtggcaggtgcctgtagtcccaggtactcgggaggctgagacaggagaatcgcttgaacctgggaggcggaggttgcagtgagccaagatctcgccactgcactccagcttgggcaatagcaagactccatctcaaaataaaataaaataaaacttagagcaaagtttaaaactgagtattcatattaagtgttttattttccatattagagatgggaagggaaccttatgtgtattttattttgttttcaaccatcaataaagttttctctagaatattgttttgaacatccttgtaaaagatttgcgagttaaactattttatttactgtctgtgagagcattgggagtaggaaacgatggactccaaagtacaagggagaatacccattttcattcagctatctggagtaaaatatcaagtacttccttcaactaatcttgtctcattcactcaccttttgatatcgaaggcagaaattgcgtttacaacactgaagaccaaagctttttaattagtaaacaagcggaacatagataatggacaatgctggccactgccattctgtgttcagaaagactatgagacctgaacatatggccaagaggaaagaagagtgacgttgtctaagatgtaatgagtgctctctgagagaatcactcaattcctattggagtgcaatccttacttgagaactttattactcttgttctgtgtagttttttttttttgtcacttccccatcagaaaagcatattctttttgatagagggtcagtgttataaataattgtcttttgaaataaaatcaaatattcatgcattgaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:55075 -> Molecular function: GO:0003674 [molecular_function] evidence: ND
GeneID:55075 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:55075 -> Biological process: GO:0008150 [biological_process] evidence: ND
GeneID:55075 -> Biological process: GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] evidence: IEA
GeneID:55075 -> Biological process: GO:0008631 [intrinsic apoptotic signaling pathway in response to oxidative stress] evidence: IEA
GeneID:55075 -> Biological process: GO:0009411 [response to UV] evidence: IEA
GeneID:55075 -> Biological process: GO:0042307 [positive regulation of protein import into nucleus] evidence: IEA
GeneID:55075 -> Biological process: GO:0042347 [negative regulation of NF-kappaB import into nucleus] evidence: IEA
GeneID:55075 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IEA
GeneID:55075 -> Biological process: GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process] evidence: IEA
GeneID:55075 -> Biological process: GO:0050728 [negative regulation of inflammatory response] evidence: IEA
GeneID:55075 -> Cellular component: GO:0005576 [extracellular region] evidence: NAS
GeneID:55075 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:55075 -> Cellular component: GO:0005635 [nuclear envelope] evidence: IEA
GeneID:55075 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:55075 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:55075 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
GeneID:55075 -> Cellular component: GO:0016020 [membrane] evidence: IEA
GeneID:55075 -> Cellular component: GO:0043293 [apoptosome] evidence: IEA
GeneID:55075 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
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