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2025-05-09 18:23:27, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_006244 2766 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens protein phosphatase 2, regulatory subunit B', beta
(PPP2R5B), mRNA.
ACCESSION NM_006244
VERSION NM_006244.3 GI:295148153
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2766)
AUTHORS Oberg,E.A., Nifoussi,S.K., Gingras,A.C. and Strack,S.
TITLE Selective proteasomal degradation of the B'beta subunit of protein
phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15
JOURNAL J. Biol. Chem. 287 (52), 43378-43389 (2012)
PUBMED 23135275
REMARK GeneRIF: KLHL15 can interact with the PP2A/B'beta heterotrimer, it
only degrades B'beta, thus promoting exchange with other regulatory
subunits.
REFERENCE 2 (bases 1 to 2766)
AUTHORS Brandt,N., Franke,K., Johannes,S., Buck,F., Harder,S., Hassel,B.,
Nitsch,R. and Schumacher,S.
TITLE B56beta, a regulatory subunit of protein phosphatase 2A, interacts
with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching
JOURNAL FASEB J. 22 (7), 2521-2533 (2008)
PUBMED 18385213
REFERENCE 3 (bases 1 to 2766)
AUTHORS Letourneux,C., Rocher,G. and Porteu,F.
TITLE B56-containing PP2A dephosphorylate ERK and their activity is
controlled by the early gene IEX-1 and ERK
JOURNAL EMBO J. 25 (4), 727-738 (2006)
PUBMED 16456541
REFERENCE 4 (bases 1 to 2766)
AUTHORS Nakada,N., Kuroda,K. and Kawahara,E.
TITLE Protein phosphatase 2A regulatory subunit Bbeta promotes MAP
kinase-mediated migration of A431 cells
JOURNAL Cell. Physiol. Biochem. 15 (1-4), 19-28 (2005)
PUBMED 15665512
REMARK GeneRIF: PP2A-Bbeta promotes cell migration through the MAPK
cascade.
REFERENCE 5 (bases 1 to 2766)
AUTHORS Dozier,C., Bonyadi,M., Baricault,L., Tonasso,L. and Darbon,J.M.
TITLE Regulation of Chk2 phosphorylation by interaction with protein
phosphatase 2A via its B' regulatory subunit
JOURNAL Biol. Cell 96 (7), 509-517 (2004)
PUBMED 15380617
REFERENCE 6 (bases 1 to 2766)
AUTHORS McCright,B., Rivers,A.M., Audlin,S. and Virshup,D.M.
TITLE The B56 family of protein phosphatase 2A (PP2A) regulatory subunits
encodes differentiation-induced phosphoproteins that target PP2A to
both nucleus and cytoplasm
JOURNAL J. Biol. Chem. 271 (36), 22081-22089 (1996)
PUBMED 8703017
REFERENCE 7 (bases 1 to 2766)
AUTHORS McCright,B., Brothman,A.R. and Virshup,D.M.
TITLE Assignment of human protein phosphatase 2A regulatory subunit genes
b56alpha, b56beta, b56gamma, b56delta, and b56epsilon
(PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to
chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12
JOURNAL Genomics 36 (1), 168-170 (1996)
PUBMED 8812429
REFERENCE 8 (bases 1 to 2766)
AUTHORS Zolnierowicz,S., Van Hoof,C., Andjelkovic,N., Cron,P., Stevens,I.,
Merlevede,W., Goris,J. and Hemmings,B.A.
TITLE The variable subunit associated with protein phosphatase 2A0
defines a novel multimember family of regulatory subunits
JOURNAL Biochem. J. 317 (PT 1), 187-194 (1996)
PUBMED 8694763
REFERENCE 9 (bases 1 to 2766)
AUTHORS McCright,B. and Virshup,D.M.
TITLE Identification of a new family of protein phosphatase 2A regulatory
subunits
JOURNAL J. Biol. Chem. 270 (44), 26123-26128 (1995)
PUBMED 7592815
REFERENCE 10 (bases 1 to 2766)
AUTHORS Cross,S.H., Charlton,J.A., Nan,X. and Bird,A.P.
TITLE Purification of CpG islands using a methylated DNA binding column
JOURNAL Nat. Genet. 6 (3), 236-244 (1994)
PUBMED 8012384
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BE883575.1, L42374.1,
AP001187.5 and BM665417.1.
On Apr 25, 2010 this sequence version replaced gi:30795206.
Summary: The product of this gene belongs to the phosphatase 2A
regulatory subunit B family. Protein phosphatase 2A is one of the
four major Ser/Thr phosphatases, and it is implicated in the
negative control of cell growth and division. It consists of a
common heteromeric core enzyme, which is composed of a catalytic
subunit and a constant regulatory subunit, that associates with a
variety of regulatory subunits. The B regulatory subunit might
modulate substrate selectivity and catalytic activity. This gene
encodes a beta isoform of the regulatory subunit B56 subfamily.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: L42374.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025083 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-297 BE883575.1 1-297
298-2242 L42374.1 1-1945
2243-2243 AP001187.5 139771-139771
2244-2745 L42374.1 1947-2448
2746-2766 BM665417.1 1-21 c
FEATURES Location/Qualifiers
source 1..2766
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q12"
gene 1..2766
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/note="protein phosphatase 2, regulatory subunit B', beta"
/db_xref="GeneID:5526"
/db_xref="HGNC:9310"
/db_xref="HPRD:09038"
/db_xref="MIM:601644"
exon 1..358
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 3..4
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="g"
/db_xref="dbSNP:371491676"
variation 81
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:372177928"
variation 170
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:60798873"
variation 211
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:114383308"
variation 214
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:61024397"
exon 359..821
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 408
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:55943854"
variation 432
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:4930690"
variation 441
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:56163683"
variation 488..489
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="a"
/db_xref="dbSNP:11404201"
variation 489..490
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="a"
/replace="ggaa"
/db_xref="dbSNP:33981788"
variation 502..505
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="cc"
/db_xref="dbSNP:369353409"
variation 503
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="c"
/db_xref="dbSNP:139876615"
variation 512..513
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="cc"
/replace="gc"
/db_xref="dbSNP:56053333"
variation 513..514
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="cc"
/db_xref="dbSNP:375310561"
misc_feature 539..541
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/note="upstream in-frame stop codon"
variation 590
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201468641"
variation 596
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="g"
/db_xref="dbSNP:368858478"
variation 617
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:367971718"
variation 619
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200592076"
CDS 623..2116
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/note="serine/threonine protein phosphatase 2A, 56 kDa
regulatory subunit, beta isoform; protein phosphatase 2,
regulatory subunit B', beta isoform; PP2A B subunit
isoform B'-beta; PP2A B subunit isoform R5-beta; PP2A B
subunit isoform B56-beta; PP2A B subunit isoform
PR61-beta"
/codon_start=1
/product="serine/threonine-protein phosphatase 2A 56 kDa
regulatory subunit beta isoform"
/protein_id="NP_006235.1"
/db_xref="GI:5453952"
/db_xref="CCDS:CCDS8085.1"
/db_xref="GeneID:5526"
/db_xref="HGNC:9310"
/db_xref="HPRD:09038"
/db_xref="MIM:601644"
/translation="
METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQELTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRRLQGTQGAKEAPLQRLTPQVAASGGQS
"
misc_feature 680..682
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 815..1954
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/note="Protein phosphatase 2A regulatory B subunit (B56
family); Region: B56; pfam01603"
/db_xref="CDD:190051"
variation 641
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199949257"
variation 655
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:371904447"
variation 657
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="g"
/db_xref="dbSNP:201904964"
variation 673
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:376524488"
variation 749
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:139878967"
variation 750
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201162064"
variation 763
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="c"
/db_xref="dbSNP:141617925"
variation 805
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146202052"
exon 822..1018
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 828
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:375715449"
variation 844
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200140478"
variation 847
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:140140368"
variation 857
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:201702050"
variation 858
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:142378216"
variation 907
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="g"
/db_xref="dbSNP:150907158"
variation 932..935
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace=""
/replace="cggg"
/db_xref="dbSNP:201085110"
variation 952
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="g"
/replace="t"
/db_xref="dbSNP:201191328"
variation 965
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201218993"
exon 1019..1120
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1048
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:139405284"
variation 1105
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:117110422"
exon 1121..1213
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1142
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:147663616"
variation 1143
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="g"
/replace="t"
/db_xref="dbSNP:150933072"
variation 1200
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="c"
/db_xref="dbSNP:200228197"
exon 1214..1344
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
exon 1345..1404
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1360
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:186585758"
variation 1371
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:142324941"
exon 1405..1513
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1405
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:144744216"
variation 1410
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="g"
/replace="t"
/db_xref="dbSNP:77695690"
variation 1437
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:147891521"
variation 1460
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:374703944"
variation 1463
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:148879767"
STS 1479..1556
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/standard_name="MARC_15219-15220:1012924404:3"
/db_xref="UniSTS:267789"
variation 1501
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="c"
/db_xref="dbSNP:368200752"
exon 1514..1567
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1518
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:143547442"
variation 1567
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:139176991"
exon 1568..1618
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1575
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:375513129"
variation 1579
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:111449778"
exon 1619..1738
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1619
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:368393421"
variation 1659
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:371550514"
variation 1696
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="t"
/db_xref="dbSNP:144621979"
variation 1712
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:138534603"
variation 1713
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:141499148"
exon 1739..1866
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1791
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="g"
/replace="t"
/db_xref="dbSNP:368921406"
variation 1800
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="c"
/db_xref="dbSNP:75667682"
exon 1867..1968
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1902
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="g"
/db_xref="dbSNP:369675898"
variation 1909
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:373704138"
variation 1958
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="g"
/db_xref="dbSNP:201780164"
exon 1969..2750
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/inference="alignment:Splign:1.39.8"
variation 1975
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:372785277"
variation 1985
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="c"
/db_xref="dbSNP:146213589"
variation 2030
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:137914776"
variation 2075
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:192831260"
variation 2095
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:185359743"
variation 2105
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="g"
/replace="t"
/db_xref="dbSNP:368931364"
variation 2159
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="t"
/db_xref="dbSNP:11558624"
variation 2249
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:142900024"
variation 2395
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:67232843"
STS 2432..2630
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/standard_name="G33092"
/db_xref="UniSTS:80324"
variation 2473
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:151092418"
STS 2510..2703
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/standard_name="A002D23"
/db_xref="UniSTS:52097"
STS 2510..2703
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/standard_name="G19958"
/db_xref="UniSTS:52096"
STS 2510..2669
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/standard_name="RH11559"
/db_xref="UniSTS:31620"
STS 2511..2692
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/standard_name="RH17836"
/db_xref="UniSTS:70958"
variation 2549
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="a"
/replace="g"
/db_xref="dbSNP:188478728"
variation 2675
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="g"
/db_xref="dbSNP:111561429"
variation 2696
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:141065909"
variation 2708
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
/replace="c"
/replace="t"
/db_xref="dbSNP:192880468"
polyA_signal 2729..2734
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
polyA_site 2750
/gene="PPP2R5B"
/gene_synonym="B56B; PR61B"
ORIGIN
ggtggggggaggtgacttgatgtcatcctgagcagctgggcggcgggtgccggtgcgcacggagccgagccggggctcccgttgcgctgcaccgcgttgggtcggagtcccaggacttcagcggagatccgcgcgctgcgacggccggtgcagagcccgccgagcgcccagtcccggcccggggctgagttgggggcatgctctagccgcccccccggagcccgggagagaacccaggagcgccgccgcccagccccagcgccccgagcggaaccgctgcgaaggggccctgaacggccgtcgccctccctacgggcagcccccgggggttggcgaccgaagtctaggttttcgagaaagccagggtgggaaccctaactggactcttcgggacccccaggaaggatctgaggcctgagccatcctcctttctaccctgtctgccccccaggactgggcagttgcaggaggccctgggggggggcccaggactgtggttgtgccccccccccaaaggccggacaggatgggaccaagttagtctgtccagtctcacccagcacctcccaggcccagagagaacccccggggctctgaaagcttgccctgccgcctgaccgccatggagacgaagctgccccctgcaagcacccccactagcccctcctcccccgggctgtcgcctgtgcccccacccgacaaggtggacggcttctcccgccgttccctccgcagagcccggccccgccgctcccacagctcctctcagttccgctatcagagcaaccagcaagagctcacaccgctgcccctgctcaaagatgtgccggcttccgagctgcacgagctgctgagccggaagctggcccagtgtggggtgatgtttgacttcttggactgtgtggccgacctcaaggggaaggaggtgaagcgggcagccctcaacgagctggtggagtgtgtggggagcacccggggtgtcctcatcgagcccgtctacccagacatcatccgcatgatctcagtgaatatcttccggactctgccgcccagtgagaaccctgaatttgaccctgaagaggatgagcccaatcttgagccttcgtggccacacctgcagctggtatatgagtttttcctgcgtttcttggagagcccagacttccagccctccgtggccaagagatatgtggatcaaaagtttgtcctgatgctcctggagctatttgatagtgaggatccccgggagcgtgagtacctcaagaccatcctgcaccgggtctatggcaagttcctgggtctccgggcctacatccgcaaacagtgcaaccacatcttcctccggttcatctatgaattcgagcacttcaatggtgtggctgagctgctggagatcctaggaagcatcatcaatggctttgcgctgcccctgaagacggagcacaagcagttcctggttcgcgtcctgatccccctgcactctgtcaagtcgctgtctgtcttccatgcccagctggcatactgtgtggtgcagttcctggagaaggatgccactctgacagagcacgtgatccgggggctgctcaaatactggccaaaaacctgcacccagaaggaggtgatgtttctgggggagatggaagagattcttgatgtcatcgagccctcccagtttgtgaagatccaggagcccctttttaagcaggtggctcgctgtgtttccagcccccatttccaggttgcagagcgggctctgtatttctggaacaatgagtatatcctaagcctcattgaggacaactgccacactgtgctgcctgctgtgtttgggaccctctaccaagtctccaaggagcactggaaccaaaccatcgtatcactgatctacaatgtgctcaagaccttcatggagatgaatgggaagctgtttgatgagctcacagcctcctacaagctggaaaagcagcaggagcagcagaaggcccaggagcgtcaggagttatggcaaggtctggaggagctgcggctacgccggctacaggggacccagggggccaaggaggcccccctccagcggcttacaccccaggtggccgccagtgggggtcagagctagacagcacctcagaaggggaaaagctaaacccagagctgtcagtccctctatcccttctcctgtccaggggcccagagagaaacacacctacccctggccttgccagagtggcttctgaggactccctgcccagcccagctttcactggggggagacgaggagaggcaatggtggtcttggcaacagaatgctcagcccctcgtggcaggacttgacaagggcaagcttgaccaggaagctgccatcagggatcttcccctgccccgcaaagctaggctccagctgcaggcgggctcccaccctctgctcctggccttgggcaagggcactcagcgcctcgcctgcccctgccttggccaatgcgaggtccttccttatccccaccatggggtccatggtctatttattctcgcccagctcaccctctacacagacactgtcctgggtgcacactcctcccttccctcgctgtgtacttccttgtcccctttttatttattgggcagggggagggggagggcacaggcaagaagagattcacagtgtcctggggtaagggggggttcacagtaatcatggtctactcctctttccgtggctgggggtagacttaataaagagagaaattcaagaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5526 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:5526 -> Molecular function: GO:0008601 [protein phosphatase type 2A regulator activity] evidence: IEA
GeneID:5526 -> Biological process: GO:0006987 [activation of signaling protein activity involved in unfolded protein response] evidence: TAS
GeneID:5526 -> Biological process: GO:0030968 [endoplasmic reticulum unfolded protein response] evidence: TAS
GeneID:5526 -> Biological process: GO:0044267 [cellular protein metabolic process] evidence: TAS
GeneID:5526 -> Cellular component: GO:0000159 [protein phosphatase type 2A complex] evidence: IEA
GeneID:5526 -> Cellular component: GO:0005737 [cytoplasm] evidence: TAS
GeneID:5526 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
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