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2025-05-09 18:37:37, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_002689 2514 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens polymerase (DNA directed), alpha 2, accessory subunit
(POLA2), mRNA.
ACCESSION NM_002689
VERSION NM_002689.2 GI:20127447
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2514)
AUTHORS Kilkenny,M.L., De Piccoli,G., Perera,R.L., Labib,K. and
Pellegrini,L.
TITLE A conserved motif in the C-terminal tail of DNA polymerase alpha
tethers primase to the eukaryotic replisome
JOURNAL J. Biol. Chem. 287 (28), 23740-23747 (2012)
PUBMED 22593576
REMARK GeneRIF: Findings indicate that tethering of primase to the
replisome by DNA polymerase alpha (pol alpha) is critical for the
normal action of DNA replication forks in eukaryotic cells.
REFERENCE 2 (bases 1 to 2514)
AUTHORS Flachsbart,F., Franke,A., Kleindorp,R., Caliebe,A., Blanche,H.,
Schreiber,S. and Nebel,A.
TITLE Investigation of genetic susceptibility factors for human longevity
- a targeted nonsynonymous SNP study
JOURNAL Mutat. Res. 694 (1-2), 13-19 (2010)
PUBMED 20800603
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 2514)
AUTHORS Michiels,S., Laplanche,A., Boulet,T., Dessen,P., Guillonneau,B.,
Mejean,A., Desgrandchamps,F., Lathrop,M., Sarasin,A. and
Benhamou,S.
TITLE Genetic polymorphisms in 85 DNA repair genes and bladder cancer
risk
JOURNAL Carcinogenesis 30 (5), 763-768 (2009)
PUBMED 19237606
REMARK GeneRIF: Observational study of gene-disease association, gene-gene
interaction, and gene-environment interaction. (HuGE Navigator)
REFERENCE 4 (bases 1 to 2514)
AUTHORS Beausoleil,S.A., Villen,J., Gerber,S.A., Rush,J. and Gygi,S.P.
TITLE A probability-based approach for high-throughput protein
phosphorylation analysis and site localization
JOURNAL Nat. Biotechnol. 24 (10), 1285-1292 (2006)
PUBMED 16964243
REFERENCE 5 (bases 1 to 2514)
AUTHORS Stelzl,U., Worm,U., Lalowski,M., Haenig,C., Brembeck,F.H.,
Goehler,H., Stroedicke,M., Zenkner,M., Schoenherr,A., Koeppen,S.,
Timm,J., Mintzlaff,S., Abraham,C., Bock,N., Kietzmann,S.,
Goedde,A., Toksoz,E., Droege,A., Krobitsch,S., Korn,B.,
Birchmeier,W., Lehrach,H. and Wanker,E.E.
TITLE A human protein-protein interaction network: a resource for
annotating the proteome
JOURNAL Cell 122 (6), 957-968 (2005)
PUBMED 16169070
REFERENCE 6 (bases 1 to 2514)
AUTHORS Huang,D., Jokela,M., Tuusa,J., Skog,S., Poikonen,K. and
Syvaoja,J.E.
TITLE E2F mediates induction of the Sp1-controlled promoter of the human
DNA polymerase epsilon B-subunit gene POLE2
JOURNAL Nucleic Acids Res. 29 (13), 2810-2821 (2001)
PUBMED 11433027
REFERENCE 7 (bases 1 to 2514)
AUTHORS Podust,V.N., Tiwari,N., Stephan,S. and Fanning,E.
TITLE Replication factor C disengages from proliferating cell nuclear
antigen (PCNA) upon sliding clamp formation, and PCNA itself
tethers DNA polymerase delta to DNA
JOURNAL J. Biol. Chem. 273 (48), 31992-31999 (1998)
PUBMED 9822671
REFERENCE 8 (bases 1 to 2514)
AUTHORS Collins,K.L., Russo,A.A., Tseng,B.Y. and Kelly,T.J.
TITLE The role of the 70 kDa subunit of human DNA polymerase alpha in DNA
replication
JOURNAL EMBO J. 12 (12), 4555-4566 (1993)
PUBMED 8223465
REFERENCE 9 (bases 1 to 2514)
AUTHORS Nasheuer,H.P., Moore,A., Wahl,A.F. and Wang,T.S.
TITLE Cell cycle-dependent phosphorylation of human DNA polymerase alpha
JOURNAL J. Biol. Chem. 266 (12), 7893-7903 (1991)
PUBMED 1902230
REFERENCE 10 (bases 1 to 2514)
AUTHORS Wang,T.S., Hu,S.Z. and Korn,D.
TITLE DNA primase from KB cells. Characterization of a primase activity
tightly associated with immunoaffinity-purified DNA
polymerase-alpha
JOURNAL J. Biol. Chem. 259 (3), 1854-1865 (1984)
PUBMED 6693436
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from BC002990.1.
On Apr 10, 2002 this sequence version replaced gi:4505928.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC001347.2, AK025315.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025085 [ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..2514
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q13.1"
gene 1..2514
/gene="POLA2"
/note="polymerase (DNA directed), alpha 2, accessory
subunit"
/db_xref="GeneID:23649"
/db_xref="HGNC:30073"
/db_xref="HPRD:10160"
variation 16
/gene="POLA2"
/replace="a"
/replace="c"
/db_xref="dbSNP:12794623"
variation 20
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:114534269"
variation 47..48
/gene="POLA2"
/replace=""
/replace="t"
/db_xref="dbSNP:34893642"
variation 177
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:116555805"
variation 204
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:78415165"
misc_feature 244..246
/gene="POLA2"
/note="upstream in-frame stop codon"
variation 276
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:187080464"
variation 297
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:374352197"
variation 325
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:367947984"
variation 329
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371818539"
CDS 343..2139
/gene="POLA2"
/note="polymerase (DNA-directed), alpha (70kD); DNA
polymerase alpha 70 kDa subunit; polymerase (DNA
directed), alpha 2 (70kD subunit)"
/codon_start=1
/product="DNA polymerase alpha subunit B"
/protein_id="NP_002680.2"
/db_xref="GI:20127448"
/db_xref="CCDS:CCDS8098.1"
/db_xref="GeneID:23649"
/db_xref="HGNC:30073"
/db_xref="HPRD:10160"
/translation="
MSASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAFCTSTHKVGLTSEILNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSWSGRGGAGNISLKVLGCPEALTGSYKSMFQKLPDIREVLTCKIEELGSELKEHYKIEAFTPLLAPAQEPVTLLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQVVIMEGINTTGRKLVATKLYEGVPLPFYQPTEEDADFEQSMVLVACGPYTTSDSITYDPLLDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIEGTRSSGSHLVFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFGLTSTDLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQLPVTPDVLIIPSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPCIAVQVVRI
"
misc_feature 385..1086
/gene="POLA2"
/note="DNA polymerase alpha subunit B N-terminal; Region:
Pol_alpha_B_N; pfam08418"
/db_xref="CDD:203937"
misc_feature 718..720
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q14181.2); phosphorylation site"
misc_feature 721..723
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q14181.2); phosphorylation site"
misc_feature 721..723
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 730..732
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q14181.2); phosphorylation site"
misc_feature 763..765
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q14181.2); phosphorylation site"
misc_feature 763..765
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 781..783
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q14181.2); phosphorylation site"
misc_feature 781..783
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 796..798
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q14181.2); phosphorylation site"
misc_feature 796..798
/gene="POLA2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1414..1989
/gene="POLA2"
/note="DNA polymerase alpha/epsilon subunit B; Region:
DNA_pol_E_B; pfam04042"
/db_xref="CDD:202861"
variation 355
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:151129443"
variation 356
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141406398"
variation 409
/gene="POLA2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373191135"
variation 411
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377753893"
variation 419
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:191135388"
variation 440
/gene="POLA2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201563360"
variation 444
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377277692"
variation 468
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370524216"
variation 474
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145143636"
variation 482
/gene="POLA2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200613332"
variation 509
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:141442372"
variation 552
/gene="POLA2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373673074"
variation 553
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140460455"
variation 573
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150431615"
variation 643
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376958217"
variation 655
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138206808"
variation 710
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370368976"
variation 713
/gene="POLA2"
/replace="a"
/replace="c"
/db_xref="dbSNP:373779147"
variation 757
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149521848"
variation 758
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:367571868"
variation 786
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371108659"
variation 813
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372504014"
variation 832
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:187158521"
variation 842
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377028201"
STS 852..1050
/gene="POLA2"
/standard_name="PMC303366P6"
/db_xref="UniSTS:272513"
variation 865
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199754207"
variation 880
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371926841"
variation 939
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:142933430"
variation 1027
/gene="POLA2"
/replace="a"
/replace="t"
/db_xref="dbSNP:181525791"
variation 1029
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138966982"
variation 1049
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200106919"
variation 1065
/gene="POLA2"
/replace="a"
/replace="t"
/db_xref="dbSNP:142911171"
variation 1101
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:201349244"
variation 1128
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200645119"
variation 1159
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147424510"
variation 1182
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372693281"
variation 1184
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:376500520"
variation 1210
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370543097"
variation 1224
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:373645442"
variation 1249
/gene="POLA2"
/replace="a"
/replace="t"
/db_xref="dbSNP:200740193"
variation 1280
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:137913617"
variation 1283
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192640239"
variation 1299
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141608215"
variation 1329
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150546843"
variation 1352
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:55765473"
variation 1362
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377231378"
variation 1368
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369223766"
variation 1387
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150043535"
variation 1444
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112783160"
variation 1470
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199986792"
variation 1494
/gene="POLA2"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:56163475"
variation 1507
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140114790"
variation 1542
/gene="POLA2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201117545"
variation 1562
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143904136"
variation 1590
/gene="POLA2"
/replace="c"
/replace="g"
/db_xref="dbSNP:146866280"
variation 1630
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148938869"
variation 1642
/gene="POLA2"
/replace="c"
/replace="g"
/db_xref="dbSNP:142790860"
variation 1647
/gene="POLA2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201506909"
variation 1672
/gene="POLA2"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:191375625"
variation 1711
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372745086"
variation 1776
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377398033"
variation 1788
/gene="POLA2"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:151070088"
variation 1789
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200610658"
variation 1832
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200848446"
variation 1834
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368001126"
variation 1839
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370249013"
variation 1846
/gene="POLA2"
/replace="a"
/replace="t"
/db_xref="dbSNP:140980676"
variation 1885
/gene="POLA2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376934780"
variation 1914
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150210701"
variation 1926
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144846742"
variation 1942..1943
/gene="POLA2"
/replace=""
/replace="c"
/db_xref="dbSNP:34968471"
variation 1983
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:34997862"
variation 1985
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:373361083"
variation 1998
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:370926282"
variation 2011
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373086775"
variation 2031
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200403723"
variation 2055
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201640265"
variation 2057
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141287498"
variation 2060
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370367077"
variation 2064
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:185175426"
variation 2082
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41541217"
variation 2089
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:487989"
variation 2105
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:7123885"
variation 2142
/gene="POLA2"
/replace="c"
/replace="g"
/db_xref="dbSNP:199847515"
variation 2152
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:4590878"
STS 2188..2416
/gene="POLA2"
/standard_name="D11S4591"
/db_xref="UniSTS:48269"
STS 2230..2384
/gene="POLA2"
/standard_name="G62107"
/db_xref="UniSTS:139143"
variation 2252
/gene="POLA2"
/replace=""
/replace="a"
/db_xref="dbSNP:41561615"
variation 2294
/gene="POLA2"
/replace="g"
/replace="t"
/db_xref="dbSNP:372342062"
STS 2315..2435
/gene="POLA2"
/standard_name="RH98539"
/db_xref="UniSTS:84889"
variation 2317
/gene="POLA2"
/replace="c"
/replace="g"
/db_xref="dbSNP:8638"
STS 2342..2463
/gene="POLA2"
/standard_name="RH17414"
/db_xref="UniSTS:13916"
STS 2344..2487
/gene="POLA2"
/standard_name="D11S4653"
/db_xref="UniSTS:64414"
variation 2351
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:188243167"
variation 2356
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:192780935"
variation 2370
/gene="POLA2"
/replace="a"
/replace="c"
/db_xref="dbSNP:11546563"
variation 2414
/gene="POLA2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189780475"
variation 2415
/gene="POLA2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184394146"
ORIGIN
cctcgtgccgcagttctgccaccgtcactgagaagctcagcggtagcttttgggaagcaggacgttctcaccaggagagcgtcctctcgagatttctgctccctccattcagggcgtttgggagccaccccttcattttttaaaaaaagtatttctctgtgaccgacggccggggccttctgacggtctgaggtcttgcttgggccagtcacctcctgtcacggtccgcggaggggggaaggataagagggcgaggagctcatcgctcgccacccccgtgggcttcttgggcgcaggtcggagctgggtgggccggctccccggcccctggcttgggcgaccatgtccgcatccgcccagcagctggcggaggagctgcagatcttcggcctagactgcgaggaggctctaattgagaaattggtagagctttgtgttcagtatggacagaatgaggagggaatggtaggcgagcttatagccttctgcaccagcacacataaagttggccttacctcagagatcctgaactcttttgagcatgagtttctgagcaaaagattatcgaaagccaggcatagtacctgcaaggacagtggccatgcaggagctagagacattgtttccattcaagagctaattgaagtggaagaagaagaggaaatcctcttgaactcttacaccacaccttcaaagggttctcagaagcgagctatctctaccccagaaacccccctaacaaaaaggagtgtgtcaactcgtagcccccatcagctactctcaccgtcaagtttctctccaagtgctactccctcccagaaatacaactcacgaagtaaccgaggagaagtggttacctccttcggcttagcacagggagtatcttggtctgggagaggaggagctggaaacatcagcctgaaggtcttgggatgtccagaggcactaactgggagctacaaatccatgtttcagaagctcccagacattcgagaagttctgacctgtaagatagaagaacttggcagcgaactcaaggaacattacaagattgaagctttcactcctttgctagccccagcacaggagcctgtcactctgctgggccagattggctgtgatagcaacgggaagctgaacaacaagtcagtgattctcgagggagaccgggaacattcctcgggtgctcaaattccagtggatttatctgagcttaaggaatattctctgtttcctggacaggttgtaattatggaaggaatcaacaccactggtaggaaacttgttgccaccaaactctacgagggtgtgccacttccattttatcagcccactgaagaggatgcagactttgagcaaagcatggtcctggttgcctgtggaccatacaccacatctgacagcatcacgtatgaccccctgcttgacctgattgctgtcatcaaccatgaccggccagatgtctgcatcctgtttggccctttcctggatgctaagcatgaacaggtggagaattgtctactgacaagtccatttgaagacattttcaagcagtgtctacgaacaattattgaaggcacaagaagctccggctcccaccttgtctttgtcccgtcattgagagatgtgcaccatgagcctgtgtacccccagccgcctttcagctactccgatctgtctcgagaggacaaaaagcaagtacagtttgtgtccgagccctgcagcctctccataaacggagtgatcttcggcttgacatccacagatctgcttttccacctgggggccgaggagatcagtagttcttccggaacttcagacagattcagccgaatactcaagcacatcttgacccagaggagctactacccactctacccgccccaagaagacatggccattgactatgagtcgttctatgtttacgcacagctgcctgtcaccccagatgtcctcatcatcccgtcagagctgaggtacttcgtgaaggatgtcctcggctgtgtctgtgtgaaccctgggcgccttaccaaagggcaggtgggaggcaccttcgcccgactctaccttaggaggccggcagcggacggggcagagaggcagagcccatgcattgctgtgcaggtcgtcaggatctgaggcttctgtcctctgctgttctctgctgtgtgggcccttaaagtcttagccaagagccaagacatagccctgtgacaaggtgaacagttgggtgggaaaggagagaggagccagccagggaggggcagctgcagtgaccaggcccagcagggaggacttgtgcagccgggcctgcctctgagtggtgcctctcctggaaggaagctcttgcttctcagtccatgctccgtgtccagaagtaagccagctgtggatcccgcccactcagaaaaggcgagaaggctttgtgattttctacatgaatcaaacacagaaacaacttttggagaaattaaattctgagtgtgaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23649 -> Molecular function: GO:0003674 [molecular_function] evidence: ND
GeneID:23649 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
GeneID:23649 -> Molecular function: GO:0003887 [DNA-directed DNA polymerase activity] evidence: IEA
GeneID:23649 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IEA
GeneID:23649 -> Biological process: GO:0000060 [protein import into nucleus, translocation] evidence: IEA
GeneID:23649 -> Biological process: GO:0000082 [G1/S transition of mitotic cell cycle] evidence: TAS
GeneID:23649 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
GeneID:23649 -> Biological process: GO:0000722 [telomere maintenance via recombination] evidence: TAS
GeneID:23649 -> Biological process: GO:0000723 [telomere maintenance] evidence: TAS
GeneID:23649 -> Biological process: GO:0006260 [DNA replication] evidence: NAS
GeneID:23649 -> Biological process: GO:0006270 [DNA replication initiation] evidence: TAS
GeneID:23649 -> Biological process: GO:0006271 [DNA strand elongation involved in DNA replication] evidence: TAS
GeneID:23649 -> Biological process: GO:0032201 [telomere maintenance via semi-conservative replication] evidence: TAS
GeneID:23649 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:23649 -> Cellular component: GO:0005634 [nucleus] evidence: NAS
GeneID:23649 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:23649 -> Cellular component: GO:0005658 [alpha DNA polymerase:primase complex] evidence: IEA
GeneID:23649 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:23649 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
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DBCLS
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