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2025-05-09 18:32:22, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001101 1852 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens actin, beta (ACTB), mRNA.
ACCESSION NM_001101
VERSION NM_001101.3 GI:168480144
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1852)
AUTHORS Lui,Y.L., Lin,Z., Lee,J.J., Chow,V.T., Poh,C.L. and Tan,E.L.
TITLE Beta-actin variant is necessary for Enterovirus 71 replication
JOURNAL Biochem. Biophys. Res. Commun. 433 (4), 607-610 (2013)
PUBMED 23535377
REMARK GeneRIF: Two variants of beta-actin, beta1 and beta2 were found in
the Enterovirus 71-susceptible rhabdomyosarcoma cells, compared to
Enterovirus 71-resistant cells that contains only one variant
beta1.
REFERENCE 2 (bases 1 to 1852)
AUTHORS Thompson,P.M., Tolbert,C.E. and Campbell,S.L.
TITLE Vinculin and metavinculin: oligomerization and interactions with
F-actin
JOURNAL FEBS Lett. 587 (8), 1220-1229 (2013)
PUBMED 23466368
REMARK GeneRIF: Studies indicate that that vinculin not only bundles actin
filaments but can also cap these filaments and promote actin
polymerization.
Review article
REFERENCE 3 (bases 1 to 1852)
AUTHORS Elam,W.A., Kang,H. and De la Cruz,E.M.
TITLE Biophysics of actin filament severing by cofilin
JOURNAL FEBS Lett. 587 (8), 1215-1219 (2013)
PUBMED 23395798
REMARK GeneRIF: Studies indicate that cofilin binds actin
stoichiometrically - one cofilin molecule per actin filament
subunit.
Review article
REFERENCE 4 (bases 1 to 1852)
AUTHORS Wakimoto,H., Shimodo,M., Satoh,Y., Kitagawa,Y., Takeuchi,K.,
Gotoh,B. and Itoh,M.
TITLE F-actin modulates measles virus cell-cell fusion and assembly by
altering the interaction between the matrix protein and the
cytoplasmic tail of hemagglutinin
JOURNAL J. Virol. 87 (4), 1974-1984 (2013)
PUBMED 23221571
REMARK GeneRIF: These results indicate that F-actin in association with
the M protein alters the interaction between the M and H proteins,
thereby modulating measles virus cell-cell fusion and assembly.
REFERENCE 5 (bases 1 to 1852)
AUTHORS Zhang,L., Xiao,R., Xiong,J., Leng,J., Ehtisham,A., Hu,Y., Ding,Q.,
Xu,H., Liu,S., Wang,J., Tang,D.G. and Zhang,Q.
TITLE Activated ERM protein plays a critical role in drug resistance of
MOLT4 cells induced by CCL25
JOURNAL PLoS ONE 8 (1), E52384 (2013)
PUBMED 23326330
REMARK GeneRIF: Data suggest that P-glycoprotein associate with the
F-actin cytoskeleton through ezrin/radixin/moesin (ERM) in
CCR9/CCL25 induced multidrug resistance of acute T-lymphocytic
leukemia (T-ALL) cells.
REFERENCE 6 (bases 1 to 1852)
AUTHORS Horisberger,M.A.
TITLE Interferon-induced human protein MxA is a GTPase which binds
transiently to cellular proteins
JOURNAL J. Virol. 66 (8), 4705-4709 (1992)
PUBMED 1629950
REFERENCE 7 (bases 1 to 1852)
AUTHORS Harris,D.E., Warshaw,D.M. and Periasamy,M.
TITLE Nucleotide sequences of the rabbit alpha-smooth-muscle and
beta-non-muscle actin mRNAs
JOURNAL Gene 112 (2), 265-266 (1992)
PUBMED 1555776
REFERENCE 8 (bases 1 to 1852)
AUTHORS Habets,G.G., van der Kammen,R.A., Willemsen,V., Balemans,M.,
Wiegant,J. and Collard,J.G.
TITLE Sublocalization of an invasion-inducing locus and other genes on
human chromosome 7
JOURNAL Cytogenet. Cell Genet. 60 (3-4), 200-205 (1992)
PUBMED 1505215
REFERENCE 9 (bases 1 to 1852)
AUTHORS Smith,S.S., Kelly,K.H. and Jockusch,B.M.
TITLE Actin co-purifies with RNA polymerase II
JOURNAL Biochem. Biophys. Res. Commun. 86 (1), 161-166 (1979)
PUBMED 435297
REFERENCE 10 (bases 1 to 1852)
AUTHORS Vandekerckhove,J. and Weber,K.
TITLE Mammalian cytoplasmic actins are the products of at least two genes
and differ in primary structure in at least 25 identified positions
from skeletal muscle actins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 75 (3), 1106-1110 (1978)
PUBMED 274701
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AK130157.1 and BC009636.1.
This sequence is a reference standard in the RefSeqGene project.
On Feb 22, 2008 this sequence version replaced gi:5016088.
Summary: This gene encodes one of six different actin proteins.
Actins are highly conserved proteins that are involved in cell
motility, structure, and integrity. This actin is a major
constituent of the contractile apparatus and one of the two
nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK222925.1, BC014861.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025088 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-1336 AK130157.1 1-1336
1337-1852 BC009636.1 71-586
FEATURES Location/Qualifiers
source 1..1852
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7p22"
gene 1..1852
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/note="actin, beta"
/db_xref="GeneID:60"
/db_xref="HGNC:132"
/db_xref="HPRD:00032"
/db_xref="MIM:102630"
exon 1..78
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/inference="alignment:Splign:1.39.8"
variation 12
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13447389"
variation 71
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="g"
/db_xref="dbSNP:11546897"
exon 79..207
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/inference="alignment:Splign:1.39.8"
variation 81
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546942"
variation 84
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="c"
/db_xref="dbSNP:11546943"
CDS 85..1212
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/note="beta cytoskeletal actin; PS1TP5-binding protein 1"
/codon_start=1
/product="actin, cytoplasmic 1"
/protein_id="NP_001092.1"
/db_xref="GI:4501885"
/db_xref="CCDS:CCDS5341.1"
/db_xref="GeneID:60"
/db_xref="HGNC:132"
/db_xref="HPRD:00032"
/db_xref="MIM:102630"
/translation="
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
"
misc_feature 88..90
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/experiment="experimental evidence, no additional details
recorded"
/note="N-acetylaspartate, in Actin, cytoplasmic 1,
N-terminally processed; propagated from
UniProtKB/Swiss-Prot (P60709.1); acetylation site"
misc_feature 91..1209
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/note="Actin; Region: Actin; pfam00022"
/db_xref="CDD:200935"
misc_feature 106..627
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/note="Nucleotide-Binding Domain of the sugar
kinase/HSP70/actin superfamily; Region:
NBD_sugar-kinase_HSP70_actin; cd00012"
/db_xref="CDD:212657"
misc_feature order(115..126,130..132,136..138,493..495,544..555)
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/note="nucleotide binding site [chemical binding]; other
site"
/db_xref="CDD:212657"
misc_feature 301..303
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/experiment="experimental evidence, no additional details
recorded"
/note="methylation site"
misc_feature 613..615
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/experiment="experimental evidence, no additional details
recorded"
/note="ADP-ribosylation site; glycosylation site"
misc_feature 736..738
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature order(937..939,1204..1206)
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/experiment="experimental evidence, no additional details
recorded"
/note="disulfide bridge bond"
misc_feature 964..966
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 964..966
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
variation 104
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546916"
variation 106
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546895"
STS 109..361
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC317352P1"
/db_xref="UniSTS:273088"
STS 117..269
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC97568P1"
/db_xref="UniSTS:273653"
variation 161
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546929"
variation 191
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="g"
/db_xref="dbSNP:11546921"
variation 193
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546914"
STS 202..276
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC24942P1"
/db_xref="UniSTS:272277"
exon 208..447
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/inference="alignment:Splign:1.39.8"
STS 223..722
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC85795P4"
/db_xref="UniSTS:273493"
STS 226..327
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC86716P1"
/db_xref="UniSTS:273551"
STS 247..1155
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC108612P1"
/db_xref="UniSTS:270141"
STS 250..1155
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC110143P1"
/db_xref="UniSTS:270184"
STS 250..627
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC201106P1"
/db_xref="UniSTS:271883"
STS 250..485
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC137792P1"
/db_xref="UniSTS:270855"
variation 252
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13447398"
STS 272..808
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC133998P8"
/db_xref="UniSTS:270713"
variation 286
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546904"
variation 290
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546912"
variation 292
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546913"
STS 308..550
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="ACTB-L"
/db_xref="UniSTS:261993"
STS 310..769
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC137757P2"
/db_xref="UniSTS:270854"
STS 313..666
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC23952P1"
/db_xref="UniSTS:272216"
STS 322..685
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC129447P1"
/db_xref="UniSTS:270591"
STS 339..468
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="LOC345651"
/db_xref="UniSTS:265879"
STS 340..669
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC356969P12"
/db_xref="UniSTS:273274"
STS 352..885
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC22644P1"
/db_xref="UniSTS:272120"
variation 371
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546931"
variation 375
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546933"
variation 376
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546910"
variation 379
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="g"
/db_xref="dbSNP:11546932"
STS 440..625
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="RI01350"
/db_xref="UniSTS:463064"
exon 448..886
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/inference="alignment:Splign:1.39.8"
STS 451..945
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC224995P1"
/db_xref="UniSTS:272113"
STS 453..770
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC99880P2"
/db_xref="UniSTS:273691"
STS 453..719
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC152551P1"
/db_xref="UniSTS:271229"
STS 455..811
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC85361P1"
/db_xref="UniSTS:273471"
STS 457..818
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC180915P1"
/db_xref="UniSTS:271667"
STS 466..719
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC275467P1"
/db_xref="UniSTS:272382"
variation 504
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:13447405"
variation 510
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:79074016"
STS 566..1030
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC117780P1"
/db_xref="UniSTS:270340"
variation 566
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546901"
variation 585
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:1064678"
STS 602..1207
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC109669P1"
/db_xref="UniSTS:270176"
variation 603..604
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546944"
STS 608..766
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC133768P1"
/db_xref="UniSTS:270660"
variation 632
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546934"
STS 652..1094
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC26753P1"
/db_xref="UniSTS:272350"
STS 673..1168
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC138261P1"
/db_xref="UniSTS:270864"
variation 698..699
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546945"
variation 737
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="c"
/db_xref="dbSNP:11546898"
variation 743
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546894"
STS 759..1204
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="GDB:624560"
/db_xref="UniSTS:158349"
STS 790..1028
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC101699P1"
/db_xref="UniSTS:270062"
STS 793..931
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="REN115794"
/db_xref="UniSTS:440589"
variation 812
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546899"
variation 841
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546925"
variation 854
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546930"
STS 867..1095
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC302066P1"
/db_xref="UniSTS:272483"
STS 878..1079
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC109689P1"
/db_xref="UniSTS:270178"
STS 878..1079
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC110200P1"
/db_xref="UniSTS:270185"
exon 887..1068
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/inference="alignment:Splign:1.39.8"
STS 890..1172
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC305683P4"
/db_xref="UniSTS:272560"
variation 915
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546896"
STS 934..1155
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC20960P1"
/db_xref="UniSTS:272003"
STS 955..1079
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC109445P1"
/db_xref="UniSTS:270169"
STS 965..1169
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC24561P1"
/db_xref="UniSTS:272264"
variation 984
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13447406"
variation 987
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13447407"
STS 1007..1165
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC305873P2"
/db_xref="UniSTS:272568"
variation 1026
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546939"
variation 1035
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13447408"
STS 1064..1381
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC151817P1"
/db_xref="UniSTS:271183"
exon 1069..1812
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/inference="alignment:Splign:1.39.8"
variation 1098
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1064790"
variation 1109
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546902"
variation 1128
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:13447409"
STS 1136..1375
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="aa658676"
/db_xref="UniSTS:186920"
STS 1145..1266
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC151001P2"
/db_xref="UniSTS:271130"
variation 1180
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546903"
STS 1249..1490
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="G15871"
/db_xref="UniSTS:6889"
variation 1299
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:1065094"
variation 1312
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13447410"
variation 1314
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:17136418"
variation 1321
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546928"
STS 1356..1587
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="ECD18704"
/db_xref="UniSTS:299714"
STS 1357..1784
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="PMC21334P2"
/db_xref="UniSTS:272037"
STS 1358..1516
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/standard_name="G49387"
/db_xref="UniSTS:109142"
variation 1413
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11546911"
variation 1422
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:13447411"
variation 1435
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546941"
variation 1444
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546919"
variation 1447
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546918"
variation 1472
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546906"
variation 1475
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="c"
/db_xref="dbSNP:11546935"
variation 1483
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546927"
variation 1492
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11546905"
variation 1527
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:1065729"
variation 1581
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546923"
variation 1594
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:3210647"
variation 1645
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:3206243"
variation 1665
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="g"
/db_xref="dbSNP:3210032"
variation 1686
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="c"
/replace="t"
/db_xref="dbSNP:3210108"
variation 1717
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="a"
/replace="g"
/db_xref="dbSNP:13447412"
variation 1723
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
/replace="g"
/replace="t"
/db_xref="dbSNP:11546924"
polyA_signal 1787..1792
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
polyA_site 1812
/gene="ACTB"
/gene_synonym="BRWS1; PS1TP5BP1"
ORIGIN
accgccgagaccgcgtccgccccgcgagcacagagcctcgcctttgccgatccgccgcccgtccacacccgccgccagctcaccatggatgatgatatcgccgcgctcgtcgtcgacaacggctccggcatgtgcaaggccggcttcgcgggcgacgatgccccccgggccgtcttcccctccatcgtggggcgccccaggcaccagggcgtgatggtgggcatgggtcagaaggattcctatgtgggcgacgaggcccagagcaagagaggcatcctcaccctgaagtaccccatcgagcacggcatcgtcaccaactgggacgacatggagaaaatctggcaccacaccttctacaatgagctgcgtgtggctcccgaggagcaccccgtgctgctgaccgaggcccccctgaaccccaaggccaaccgcgagaagatgacccagatcatgtttgagaccttcaacaccccagccatgtacgttgctatccaggctgtgctatccctgtacgcctctggccgtaccactggcatcgtgatggactccggtgacggggtcacccacactgtgcccatctacgaggggtatgccctcccccatgccatcctgcgtctggacctggctggccgggacctgactgactacctcatgaagatcctcaccgagcgcggctacagcttcaccaccacggccgagcgggaaatcgtgcgtgacattaaggagaagctgtgctacgtcgccctggacttcgagcaagagatggccacggctgcttccagctcctccctggagaagagctacgagctgcctgacggccaggtcatcaccattggcaatgagcggttccgctgccctgaggcactcttccagccttccttcctgggcatggagtcctgtggcatccacgaaactaccttcaactccatcatgaagtgtgacgtggacatccgcaaagacctgtacgccaacacagtgctgtctggcggcaccaccatgtaccctggcattgccgacaggatgcagaaggagatcactgccctggcacccagcacaatgaagatcaagatcattgctcctcctgagcgcaagtactccgtgtggatcggcggctccatcctggcctcgctgtccaccttccagcagatgtggatcagcaagcaggagtatgacgagtccggcccctccatcgtccaccgcaaatgcttctaggcggactatgacttagttgcgttacaccctttcttgacaaaacctaacttgcgcagaaaacaagatgagattggcatggctttatttgttttttttgttttgttttggttttttttttttttttggcttgactcaggatttaaaaactggaacggtgaaggtgacagcagtcggttggagcgagcatcccccaaagttcacaatgtggccgaggactttgattgcacattgttgtttttttaatagtcattccaaatatgagatgcgttgttacaggaagtcccttgccatcctaaaagccaccccacttctctctaaggagaatggcccagtcctctcccaagtccacacaggggaggtgatagcattgctttcgtgtaaattatgtaatgcaaaatttttttaatcttcgccttaatacttttttattttgttttattttgaatgatgagccttcgtgcccccccttcccccttttttgtcccccaacttgagatgtatgaaggcttttggtctccctgggagtgggtggaggcagccagggcttacctgtacactgacttgagaccagttgaataaaagtgcacaccttaaaaatgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:60 -> Molecular function: GO:0005200 [structural constituent of cytoskeleton] evidence: TAS
GeneID:60 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:60 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:60 -> Molecular function: GO:0019894 [kinesin binding] evidence: IPI
GeneID:60 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
GeneID:60 -> Molecular function: GO:0030957 [Tat protein binding] evidence: IPI
GeneID:60 -> Molecular function: GO:0050998 [nitric-oxide synthase binding] evidence: IPI
GeneID:60 -> Biological process: GO:0006457 [protein folding] evidence: TAS
GeneID:60 -> Biological process: GO:0006928 [cellular component movement] evidence: TAS
GeneID:60 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
GeneID:60 -> Biological process: GO:0007596 [blood coagulation] evidence: TAS
GeneID:60 -> Biological process: GO:0016044 [cellular membrane organization] evidence: TAS
GeneID:60 -> Biological process: GO:0034329 [cell junction assembly] evidence: TAS
GeneID:60 -> Biological process: GO:0034332 [adherens junction organization] evidence: TAS
GeneID:60 -> Biological process: GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] evidence: TAS
GeneID:60 -> Biological process: GO:0044267 [cellular protein metabolic process] evidence: TAS
GeneID:60 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:60 -> Biological process: GO:0045216 [cell-cell junction organization] evidence: TAS
GeneID:60 -> Biological process: GO:0051084 ['de novo' posttranslational protein folding] evidence: TAS
GeneID:60 -> Cellular component: GO:0005737 [cytoplasm] evidence: TAS
GeneID:60 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:60 -> Cellular component: GO:0005856 [cytoskeleton] evidence: TAS
GeneID:60 -> Cellular component: GO:0014069 [postsynaptic density] evidence: IEA
GeneID:60 -> Cellular component: GO:0030424 [axon] evidence: IEA
GeneID:60 -> Cellular component: GO:0030529 [ribonucleoprotein complex] evidence: IDA
GeneID:60 -> Cellular component: GO:0030863 [cortical cytoskeleton] evidence: IEA
GeneID:60 -> Cellular component: GO:0035267 [NuA4 histone acetyltransferase complex] evidence: IDA
GeneID:60 -> Cellular component: GO:0070062 [extracellular vesicular exosome] evidence: IDA
GeneID:60 -> Cellular component: GO:0070688 [MLL5-L complex] evidence: IDA
by
@meso_cacase at
DBCLS
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