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2025-05-09 18:39:30, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_032408 6133 bp mRNA linear PRI 15-JUN-2013
DEFINITION Homo sapiens bromodomain adjacent to zinc finger domain, 1B
(BAZ1B), mRNA.
ACCESSION NM_032408
VERSION NM_032408.3 GI:264681496
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6133)
AUTHORS Kottgen,A., Albrecht,E., Teumer,A., Vitart,V., Krumsiek,J.,
Hundertmark,C., Pistis,G., Ruggiero,D., O'Seaghdha,C.M., Haller,T.,
Yang,Q., Tanaka,T., Johnson,A.D., Kutalik,Z., Smith,A.V., Shi,J.,
Struchalin,M., Middelberg,R.P., Brown,M.J., Gaffo,A.L., Pirastu,N.,
Li,G., Hayward,C., Zemunik,T., Huffman,J., Yengo,L., Zhao,J.H.,
Demirkan,A., Feitosa,M.F., Liu,X., Malerba,G., Lopez,L.M., van der
Harst,P., Li,X., Kleber,M.E., Hicks,A.A., Nolte,I.M., Johansson,A.,
Murgia,F., Wild,S.H., Bakker,S.J., Peden,J.F., Dehghan,A.,
Steri,M., Tenesa,A., Lagou,V., Salo,P., Mangino,M., Rose,L.M.,
Lehtimaki,T., Woodward,O.M., Okada,Y., Tin,A., Muller,C.,
Oldmeadow,C., Putku,M., Czamara,D., Kraft,P., Frogheri,L.,
Thun,G.A., Grotevendt,A., Gislason,G.K., Harris,T.B., Launer,L.J.,
McArdle,P., Shuldiner,A.R., Boerwinkle,E., Coresh,J., Schmidt,H.,
Schallert,M., Martin,N.G., Montgomery,G.W., Kubo,M., Nakamura,Y.,
Tanaka,T., Munroe,P.B., Samani,N.J., Jacobs,D.R. Jr., Liu,K.,
D'Adamo,P., Ulivi,S., Rotter,J.I., Psaty,B.M., Vollenweider,P.,
Waeber,G., Campbell,S., Devuyst,O., Navarro,P., Kolcic,I.,
Hastie,N., Balkau,B., Froguel,P., Esko,T., Salumets,A., Khaw,K.T.,
Langenberg,C., Wareham,N.J., Isaacs,A., Kraja,A., Zhang,Q.,
Wild,P.S., Scott,R.J., Holliday,E.G., Org,E., Viigimaa,M.,
Bandinelli,S., Metter,J.E., Lupo,A., Trabetti,E., Sorice,R.,
Doring,A., Lattka,E., Strauch,K., Theis,F., Waldenberger,M.,
Wichmann,H.E., Davies,G., Gow,A.J., Bruinenberg,M., Stolk,R.P.,
Kooner,J.S., Zhang,W., Winkelmann,B.R., Boehm,B.O., Lucae,S.,
Penninx,B.W., Smit,J.H., Curhan,G., Mudgal,P., Plenge,R.M.,
Portas,L., Persico,I., Kirin,M., Wilson,J.F., Mateo Leach,I., van
Gilst,W.H., Goel,A., Ongen,H., Hofman,A., Rivadeneira,F.,
Uitterlinden,A.G., Imboden,M., von Eckardstein,A., Cucca,F.,
Nagaraja,R., Piras,M.G., Nauck,M., Schurmann,C., Budde,K.,
Ernst,F., Farrington,S.M., Theodoratou,E., Prokopenko,I.,
Stumvoll,M., Jula,A., Perola,M., Salomaa,V., Shin,S.Y.,
Spector,T.D., Sala,C., Ridker,P.M., Kahonen,M., Viikari,J.,
Hengstenberg,C., Nelson,C.P., Meschia,J.F., Nalls,M.A., Sharma,P.,
Singleton,A.B., Kamatani,N., Zeller,T., Burnier,M., Attia,J.,
Laan,M., Klopp,N., Hillege,H.L., Kloiber,S., Choi,H., Pirastu,M.,
Tore,S., Probst-Hensch,N.M., Volzke,H., Gudnason,V., Parsa,A.,
Schmidt,R., Whitfield,J.B., Fornage,M., Gasparini,P.,
Siscovick,D.S., Polasek,O., Campbell,H., Rudan,I., Bouatia-Naji,N.,
Metspalu,A., Loos,R.J., van Duijn,C.M., Borecki,I.B., Ferrucci,L.,
Gambaro,G., Deary,I.J., Wolffenbuttel,B.H., Chambers,J.C., Marz,W.,
Pramstaller,P.P., Snieder,H., Gyllensten,U., Wright,A.F., Navis,G.,
Watkins,H., Witteman,J.C., Sanna,S., Schipf,S., Dunlop,M.G.,
Tonjes,A., Ripatti,S., Soranzo,N., Toniolo,D., Chasman,D.I.,
Raitakari,O., Kao,W.H., Ciullo,M., Fox,C.S., Caulfield,M.,
Bochud,M. and Gieger,C.
CONSRTM LifeLines Cohort Study; CARDIoGRAM Consortium; DIAGRAM Consortium;
ICBP Consortium; MAGIC Consortium
TITLE Genome-wide association analyses identify 18 new loci associated
with serum urate concentrations
JOURNAL Nat. Genet. 45 (2), 145-154 (2013)
PUBMED 23263486
REFERENCE 2 (bases 1 to 6133)
AUTHORS Lundqvist,J., Hansen,S.K. and Lykkesfeldt,A.E.
TITLE Vitamin D analog EB1089 inhibits aromatase expression by
dissociation of comodulator WSTF from the CYP19A1 promoter-a new
regulatory pathway for aromatase
JOURNAL Biochim. Biophys. Acta 1833 (1), 40-47 (2013)
PUBMED 23085504
REMARK GeneRIF: EB1089 inhibits aromatase expression by dissociation of
comodulator WSTF from the CYP19A1 promoter.
REFERENCE 3 (bases 1 to 6133)
AUTHORS Cornelis,M.C., Monda,K.L., Yu,K., Paynter,N., Azzato,E.M.,
Bennett,S.N., Berndt,S.I., Boerwinkle,E., Chanock,S.,
Chatterjee,N., Couper,D., Curhan,G., Heiss,G., Hu,F.B.,
Hunter,D.J., Jacobs,K., Jensen,M.K., Kraft,P., Landi,M.T.,
Nettleton,J.A., Purdue,M.P., Rajaraman,P., Rimm,E.B., Rose,L.M.,
Rothman,N., Silverman,D., Stolzenberg-Solomon,R., Subar,A.,
Yeager,M., Chasman,D.I., van Dam,R.M. and Caporaso,N.E.
TITLE Genome-wide meta-analysis identifies regions on 7p21 (AHR) and
15q24 (CYP1A2) as determinants of habitual caffeine consumption
JOURNAL PLoS Genet. 7 (4), E1002033 (2011)
PUBMED 21490707
REFERENCE 4 (bases 1 to 6133)
AUTHORS Barnett,C. and Krebs,J.E.
TITLE WSTF does it all: a multifunctional protein in transcription,
repair, and replication
JOURNAL Biochem. Cell Biol. 89 (1), 12-23 (2011)
PUBMED 21326359
REMARK GeneRIF: This review describes the three known WSTF-containing
complexes and discuss their various roles as well as mechanisms of
regulating WSTF activity.
Review article
REFERENCE 5 (bases 1 to 6133)
AUTHORS Waterworth,D.M., Ricketts,S.L., Song,K., Chen,L., Zhao,J.H.,
Ripatti,S., Aulchenko,Y.S., Zhang,W., Yuan,X., Lim,N., Luan,J.,
Ashford,S., Wheeler,E., Young,E.H., Hadley,D., Thompson,J.R.,
Braund,P.S., Johnson,T., Struchalin,M., Surakka,I., Luben,R.,
Khaw,K.T., Rodwell,S.A., Loos,R.J., Boekholdt,S.M., Inouye,M.,
Deloukas,P., Elliott,P., Schlessinger,D., Sanna,S., Scuteri,A.,
Jackson,A., Mohlke,K.L., Tuomilehto,J., Roberts,R., Stewart,A.,
Kesaniemi,Y.A., Mahley,R.W., Grundy,S.M., McArdle,W., Cardon,L.,
Waeber,G., Vollenweider,P., Chambers,J.C., Boehnke,M.,
Abecasis,G.R., Salomaa,V., Jarvelin,M.R., Ruokonen,A., Barroso,I.,
Epstein,S.E., Hakonarson,H.H., Rader,D.J., Reilly,M.P.,
Witteman,J.C., Hall,A.S., Samani,N.J., Strachan,D.P., Barter,P.,
van Duijn,C.M., Kooner,J.S., Peltonen,L., Wareham,N.J.,
McPherson,R., Mooser,V. and Sandhu,M.S.
CONSRTM Wellcome Trust Case Control Consortium
TITLE Genetic variants influencing circulating lipid levels and risk of
coronary artery disease
JOURNAL Arterioscler. Thromb. Vasc. Biol. 30 (11), 2264-2276 (2010)
PUBMED 20864672
REFERENCE 6 (bases 1 to 6133)
AUTHORS Bozhenok,L., Wade,P.A. and Varga-Weisz,P.
TITLE WSTF-ISWI chromatin remodeling complex targets heterochromatic
replication foci
JOURNAL EMBO J. 21 (9), 2231-2241 (2002)
PUBMED 11980720
REMARK Erratum:[EMBO J 2002 Jun 17;21(12):3212]
REFERENCE 7 (bases 1 to 6133)
AUTHORS Pascual,J., Martinez-Yamout,M., Dyson,H.J. and Wright,P.E.
TITLE Structure of the PHD zinc finger from human Williams-Beuren
syndrome transcription factor
JOURNAL J. Mol. Biol. 304 (5), 723-729 (2000)
PUBMED 11124022
REFERENCE 8 (bases 1 to 6133)
AUTHORS Jones,M.H., Hamana,N., Nezu,Ji. and Shimane,M.
TITLE A novel family of bromodomain genes
JOURNAL Genomics 63 (1), 40-45 (2000)
PUBMED 10662543
REFERENCE 9 (bases 1 to 6133)
AUTHORS Lu,X., Meng,X., Morris,C.A. and Keating,M.T.
TITLE A novel human gene, WSTF, is deleted in Williams syndrome
JOURNAL Genomics 54 (2), 241-249 (1998)
PUBMED 9828126
REFERENCE 10 (bases 1 to 6133)
AUTHORS Peoples,R.J., Cisco,M.J., Kaplan,P. and Francke,U.
TITLE Identification of the WBSCR9 gene, encoding a novel transcriptional
regulator, in the Williams-Beuren syndrome deletion at 7q11.23
JOURNAL Cytogenet. Cell Genet. 82 (3-4), 238-246 (1998)
PUBMED 9858827
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA739467.1, BC136520.1,
AF084479.1 and BU632531.1.
This sequence is a reference standard in the RefSeqGene project.
On Nov 10, 2009 this sequence version replaced gi:115387100.
Summary: This gene encodes a member of the bromodomain protein
family. The bromodomain is a structural motif characteristic of
proteins involved in chromatin-dependent regulation of
transcription. This gene is deleted in Williams-Beuren syndrome, a
developmental disorder caused by deletion of multiple genes at
7q11.23. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF072810.1, AF084479.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-167 DA739467.1 14-180
168-2388 BC136520.1 1-2221
2389-3954 AF084479.1 2321-3886
3955-5402 BC136520.1 3788-5235
5403-6110 AF084479.1 5335-6042
6111-6133 BU632531.1 1-23 c
FEATURES Location/Qualifiers
source 1..6133
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q11.23"
gene 1..6133
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="bromodomain adjacent to zinc finger domain, 1B"
/db_xref="GeneID:9031"
/db_xref="HGNC:961"
/db_xref="HPRD:10416"
/db_xref="MIM:605681"
exon 1..459
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
STS 141..386
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/standard_name="D7S3300"
/db_xref="UniSTS:254199"
misc_feature 179..181
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="upstream in-frame stop codon"
CDS 353..4804
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/EC_number="2.7.10.2"
/note="transcription factor WSTF; hWALp2; williams
syndrome transcription factor; williams-Beuren syndrome
chromosomal region 9 protein; williams-Beuren syndrome
chromosomal region 10 protein"
/codon_start=1
/product="tyrosine-protein kinase BAZ1B"
/protein_id="NP_115784.1"
/db_xref="GI:14670392"
/db_xref="CCDS:CCDS5549.1"
/db_xref="GeneID:9031"
/db_xref="HGNC:961"
/db_xref="HPRD:10416"
/db_xref="MIM:605681"
/translation="
MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVKFEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK
"
misc_feature 353..1387
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UIG0.2);
Region: Mediates the tyrosine-protein kinase activity"
misc_feature 410..712
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="ATP-utilising chromatin assembly and remodelling
N-terminal; Region: WAC_Acf1_DNA_bd; pfam10537"
/db_xref="CDD:204507"
misc_feature 830..832
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 851..853
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 917..919
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 971..991
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UIG0.2);
Region: C motif"
misc_feature 1148..1150
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q9UIG0.2); phosphorylation site"
misc_feature 1304..1306
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1340..1342
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 1385..1387
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 1391..1393
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 1397..1399
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 1433..1435
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 1433..1435
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1472..1474
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 2162..2356
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="domain in different transcription and chromosome
remodeling factors; Region: DDT; smart00571"
/db_xref="CDD:128841"
misc_feature 2447..2449
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 2465..2467
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 2465..2467
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2474..2476
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 2474..2476
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2498..2500
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 2651..>3037
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="TolA protein; Region: tolA_full; TIGR02794"
/db_xref="CDD:211764"
misc_feature 3185..3187
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3191..3193
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 3791..3793
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3908..4054
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="PHD-finger; Region: PHD; pfam00628"
/db_xref="CDD:201356"
misc_feature 4295..4297
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 4376..4378
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 4376..4378
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4382..4672
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="Bromodomain; Williams syndrome transcription
factor-like subfamily (WSTF-like). The Williams-Beuren
syndrome deletion transcript 9 is a putative
transcriptional regulator. WSTF was found to play a role
in vitamin D-mediated transcription as part of two...;
Region: Bromo_WSTF_like; cd05505"
/db_xref="CDD:99937"
misc_feature order(4454..4456,4469..4471,4478..4480,4595..4597,
4607..4609,4625..4627)
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/note="putative acetyllysine binding site [chemical
binding]; other site"
/db_xref="CDD:99937"
misc_feature 4754..4756
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UIG0.2); phosphorylation site"
misc_feature 4754..4756
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4754..4756
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
exon 460..576
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 577..721
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 722..923
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 924..1045
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 1046..1243
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 1244..2945
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
STS 1381..2390
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/standard_name="D7S3301"
/db_xref="UniSTS:254200"
STS 1631..1724
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/standard_name="GDB:1318100"
/db_xref="UniSTS:51751"
variation 2389
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:2074754"
variation 2463
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/replace="a"
/replace="g"
/db_xref="dbSNP:1802417"
exon 2946..3084
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 3085..3218
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 3219..3324
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 3325..3423
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 3424..3601
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 3602..3784
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 3785..3932
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 3933..4080
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 4081..4196
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 4197..4342
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 4343..4446
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
exon 4447..4819
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
STS 4583..4680
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/standard_name="GDB:4585423"
/db_xref="UniSTS:75970"
variation 4654
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/replace="a"
/replace="g"
/db_xref="dbSNP:1178978"
exon 4820..6115
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/inference="alignment:Splign:1.39.8"
polyA_signal 4978..4983
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
polyA_site 4997
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
variation 5273
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/replace="c"
/replace="g"
/db_xref="dbSNP:1629235"
STS 5290..6090
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/standard_name="BAZ1B_3920"
/db_xref="UniSTS:462055"
variation 5823
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/replace="g"
/replace="t"
/db_xref="dbSNP:799220"
STS 5931..6099
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/standard_name="G20570"
/db_xref="UniSTS:77103"
STS 5931..6099
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/standard_name="RH17036"
/db_xref="UniSTS:92238"
variation 6011
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
/replace=""
/replace="t"
/db_xref="dbSNP:66527463"
polyA_signal 6055..6060
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
polyA_signal 6072..6077
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
polyA_site 6077
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
polyA_site 6115
/gene="BAZ1B"
/gene_synonym="WBSCR10; WBSCR9; WSTF"
ORIGIN
cgttggccgggcccgggggaggaggggaatctcccgccatttttcaataatttcctccggtgctgctgaggaggagtcgtgactgccggccgccgggacccgaagcggaggtcggcggggggctgctgggaggcgcggcggtgtgcgcgggagctctgcgccgtggcgttccgctccatgactgtcgcgcggccgcgccggcggtgagggagccggagttcgcgccgccctctcacccctcccttcccccaccccacccccgggcgcctggcgctcgctccgggccgcggggcctagtgctgcgccgcggggccggccccagcagccgccagtccccaccgccgccgccgcgatggcgccgctcctgggccgcaagcccttcccgctggtgaagccgttgcccggagaggagccgctcttcaccatcccgcacactcaggaggccttccgcacccgggaagagtatgaagcccgcttggaaaggtacagtgagcgcatttggacgtgcaagagtactggaagcagtcagctaacacacaaggaagcctgggaggaagaacaggaagttgctgagcttttgaaggaggagtttcctgcctggtatgagaagcttgttctggaaatggttcaccataacacagcctccttagagaagttagtagatactgcttggttggagatcatgaccaaatatgctgtgggagaagagtgtgacttcgaggttgggaaggagaaaatgctcaaggtgaagattgtgaagattcatcctttggagaaagtggatgaagaggccactgagaagaaatctgatggtgcctgtgattctccatcaagtgacaaagagaactccagtcagattgctcaggaccatcagaagaaggagacagttgtgaaagaggatgaaggaaggagagagagtattaatgacagagcacgtagatcgccacgaaaacttcctacttcattaaaaaaaggagaaaggaaatgggctcctccaaaatttctgcctcacaaatatgatgtgaaactacaaaatgaagataagatcatcagtaacgtgccagcagacagcttgattcgtacagagcgcccaccaaataaggagatagttcgatactttatacggcataatgcattacgagctggtactggtgaaaatgcaccttgggtcgtagaagatgaattggtgaagaaatactctctgcccagcaagttcagtgactttttacttgatccatacaagtatatgactctcaacccttctactaagaggaagaatactggatccccagacaggaagccctcaaagaaatccaagacagacaactcttctcttagttcaccactaaatcctaagttatggtgtcacgtacacttgaagaagtcattgagtggctcgccactcaaagtgaagaactcaaagaattccaaatctcctgaagaacatctagaagaaatgatgaagatgatgtcgcccaataagctgcacactaactttcacattcctaaaaaaggcccacctgccaagaaaccagggaagcacagtgacaagcctttgaaggcaaagggcagaagcaaaggcatcctgaatggacagaaatccacagggaattccaaatctcccaaaaaaggactgaagactcctaaaaccaaaatgaagcagatgactttgttggatatggccaaaggcacgcagaagatgacacgagccccacggaattctgggggtacacctaggacctctagtaaacctcataaacatctgcctcctgcagccctacacctcattgcatactacaaagaaaacaaagacagggaggacaagaggagcgccctgtcctgtgttatctccaaaacagctcgtcttctctctagtgaagatagagctcgtctcccagaagaattgcgaagtcttgttcaaaaacgctatgaacttctagagcacaaaaagaggtgggcttctatgtctgaagaacaacggaaagaatatttgaaaaagaaacgggaggagctgaaaaagaagttgaaggaaaaagccaaagaacgaagagagaaagaaatgcttgagagattagaaaaacagaagcggtatgaggaccaagagttaactggcaaaaaccttccagcattcagattggtggatacccctgaagggctgcccaacacgctgtttggggatgtggccatggtggtggaattcttgagctgttattctgggctacttttaccagatgctcagtatcctattactgctgtgtcccttatggaagccttgagtgcagataagggtggctttttataccttaacagggtgttggtcatcctcttacagaccctcctacaagatgagatagcagaagactatggtgaattgggaatgaagctgtcggaaatccccttgactctgcattctgtttcagagctggtgcggctctgcttgcgcagatctgatgttcaggaggaaagcgagggctcagacacagatgacaataaagattcagctgcatttgaggataatgaggtacaagatgagttcctagaaaagctggagacctctgaattttttgagctgacgtcagaggagaagctacagatcttgacagcactgtgccaccggatcctcatgacatactcagtgcaagaccacatggagaccagacagcagatgtctgcagagttgtggaaggaacggcttgctgtgttgaaggaagaaaatgataagaagagagcagagaaacagaaacggaaagaaatggaagccaaaaataaagaaaatggaaaagttgagaatgggttaggcaaaactgataggaaaaaagaaattgtgaagtttgagccccaagtagatacagaagctgaagacatgattagtgctgtgaagagcagaaggttgcttgccattcaagctaagaaggaacgggaaatccaggaaagagaaatgaaagtgaaactggaacgccaagctgaagaagaacgaatacggaagcacaaagcagctgctgagaaagctttccaggaagggattgccaaggccaaactagtcatgcgcaggactcctattggcacagatcgaaaccataatagatactggctcttctcagatgaagttccaggattattcattgaaaaaggctgggtacatgacagcattgactaccgattcaaccatcactgcaaagaccacacagtctctggtgatgaggattactgtcctcgcagtaagaaagcaaacttaggtaaaaatgcaagcatgaacacacaacatggaacagcaacagaagttgctgtagagacaaccacacccaaacaaggacagaacctatggtttttatgtgatagtcaaaaggagctggatgagttgctaaactgtcttcaccctcagggaataagagaaagtcaacttaaagagagactagagaagaggtaccaggacattattcactctattcatctagcacggaagccaaatttgggtctaaaatcttgtgatggcaaccaggagcttttaaacttccttcgtagtgatctcattgaagttgcaacaaggttacaaaaaggaggacttggatatgtggaagaaacatcagaatttgaagcccgggtcatttcattagagaaattgaaggattttggtgagtgtgtgattgcccttcaggccagtgtcataaagaaatttctccaaggcttcatggctcccaagcaaaagagaagaaaactccaaagtgaagattcagcaaaaactgaggaagtggatgaagagaagaaaatggtagaggaagcaaaggttgcatctgcactggagaaatggaagacagcaatccgggaagctcagactttctccaggatgcacgtgctgcttgggatgcttgatgcctgtatcaagtgggatatgtccgcagaaaatgctaggtgcaaagtttgtcgaaagaaaggtgaggatgacaaattgatcttgtgtgatgagtgtaataaagccttccacctgttttgtctgaggccggccctctatgaagtaccagatggtgagtggcagtgcccagcttgccagcccgctactgccaggcgcaactcccgtggcaggaactatactgaagagtctgcttctgaggacagtgaagatgatgagagtgatgaagaggaggaggaggaagaagaggaggaggaggaagaagattatgaggtggctggtttgcgattgagacctcgaaagaccatccggggcaagcacagcgtcatcccccctgcagcaaggtcaggccggcgcccgggtaagaagccacactctaccaggaggtctcagcccaaggcaccacctgtggatgatgctgaggtggatgagctggtgcttcagaccaagcggagctcccggaggcaaagcctggagctgcagaagtgtgaagagatcctccacaagatcgtgaagtaccgcttcagctggcccttcagggagcctgtgaccagagatgaggccgaggactactatgatgtgatcacgcaccccatggactttcagacagtgcagaacaaatgttcctgtgggagctaccgctctgtgcaggagtttcttactgacatgaagcaagtgtttaccaatgctgaggtttacaactgccgtggcagccatgtgctaagctgcatggtgaagacagaacagtgtctagtggctctgttgcataaacaccttcctggccacccatatgtccgcaggaagcgcaagaagtttcctgataggcttgctgaagatgaaggggacagtgagccagaggccgttggacagtccaggggacgaagacagaagaagtagagaggcagggccgtggtgacagtatcagtgagtgccatacagaattgtgtattcaccagcatcatgaaacagttgtggtcttttgagttgatcttggcagagtaaagggacgtgtcctggagccattcctgaatctccccttctttgtgacagctcctcccacccccccaaaaaataaaaaaaccacaaaaaacaaaaaaacaaaactaaggcacttcacttagagactggagtcctgcttataatcatgcatataacctttactttgatggatctggccagaggggtgttggagcccagcccacccacataccagtcaagctcttaggggagcagaagaaaagcaggaagaatttaaatgtttaattttttttttaaattgacttttctagttattaaaagttgcttgtttcagcagtgatattgtataaagaacatcttgtaagatactcctgacatcttgctttagcacatgtacagtacagtttctatgataatgtgtttgctctaacttccctggcttctccttcagcccatccactctcctctagagcagttgggttggaggctcattgaggcaagcagcaacattggagggggagcagggcagtgctgtgtctgctgcctcccatgcccgttctgacctcagccttggaactcctcaagaacctgaagattccagtggtcagtgtcggtggggggtgggaggagagagcggcagagaagctctgagagccccttcccccacaacaaatctagctctagttgttatatttaggcaaaactttgtagtcttctttcccttttatgatggattttgataaaagtacaaaacagggtttttcttttttatcacctttgaatttggaaattttgagcacccaagctcttctgtacctatttaaagtccaccaaggggactgcagctcctagaacatgagaatcaagcctcttaattttaaactgcggaatgtggcctctgcttcctccgtcctcctgcccaaggacgacgaggattgctccagggctgctgggtagtttaccgtcccttctataggcatggagttggcactgacatcacagcttcataaccccaccaccgccagcttcccctgcctcctacatccagtctgttcttgttcatagtgagaatcctgtgttcccacttcagtgacacctgaattgtttgttgttgttttttttttttattgtcttcaaagaggaagggccccattaaagggtgaacttgtaataaattggaatttcaaataaacctcatgtacttgtgtttataaagaagaaaccactctgaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9031 -> Molecular function: GO:0003682 [chromatin binding] evidence: IDA
GeneID:9031 -> Molecular function: GO:0004713 [protein tyrosine kinase activity] evidence: IDA
GeneID:9031 -> Molecular function: GO:0004715 [non-membrane spanning protein tyrosine kinase activity] evidence: IEA
GeneID:9031 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:9031 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:9031 -> Molecular function: GO:0008270 [zinc ion binding] evidence: NAS
GeneID:9031 -> Molecular function: GO:0032947 [protein complex scaffold] evidence: IDA
GeneID:9031 -> Molecular function: GO:0035173 [histone kinase activity] evidence: IDA
GeneID:9031 -> Molecular function: GO:0042809 [vitamin D receptor binding] evidence: IPI
GeneID:9031 -> Molecular function: GO:0070577 [histone acetyl-lysine binding] evidence: IDA
GeneID:9031 -> Molecular function: GO:0071884 [vitamin D receptor activator activity] evidence: IMP
GeneID:9031 -> Biological process: GO:0003007 [heart morphogenesis] evidence: ISS
GeneID:9031 -> Biological process: GO:0006302 [double-strand break repair] evidence: ISS
GeneID:9031 -> Biological process: GO:0006337 [nucleosome disassembly] evidence: IDA
GeneID:9031 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: NAS
GeneID:9031 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: ISS
GeneID:9031 -> Biological process: GO:0006974 [response to DNA damage stimulus] evidence: IDA
GeneID:9031 -> Biological process: GO:0016572 [histone phosphorylation] evidence: IDA
GeneID:9031 -> Biological process: GO:0034725 [DNA replication-dependent nucleosome disassembly] evidence: IMP
GeneID:9031 -> Biological process: GO:0043044 [ATP-dependent chromatin remodeling] evidence: IDA
GeneID:9031 -> Biological process: GO:0048096 [chromatin-mediated maintenance of transcription] evidence: ISS
GeneID:9031 -> Cellular component: GO:0000793 [condensed chromosome] evidence: IEA
GeneID:9031 -> Cellular component: GO:0005721 [centromeric heterochromatin] evidence: IEA
GeneID:9031 -> Cellular component: GO:0043596 [nuclear replication fork] evidence: IDA
GeneID:9031 -> Cellular component: GO:0071778 [WINAC complex] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_115784 -> EC 2.7.10.2
by
@meso_cacase at
DBCLS
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