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2025-05-09 18:47:32, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_134442 9794 bp mRNA linear PRI 26-MAY-2013
DEFINITION Homo sapiens cAMP responsive element binding protein 1 (CREB1),
transcript variant B, mRNA.
ACCESSION NM_134442
VERSION NM_134442.3 GI:215490110
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 9794)
AUTHORS Hoang,T., Fenne,I.S., Madsen,A., Bozickovic,O., Johannessen,M.,
Bergsvag,M., Lien,E.A., Stallcup,M.R., Sagen,J.V., Moens,U. and
Mellgren,G.
TITLE cAMP response element-binding protein interacts with and stimulates
the proteasomal degradation of the nuclear receptor coactivator
GRIP1
JOURNAL Endocrinology 154 (4), 1513-1527 (2013)
PUBMED 23462962
REMARK GeneRIF: cAMP response element-binding protein (CREB) downregulates
GRIP1 and is necessary for the PKA-stimulated degradation of GRIP1,
which leads to changes in the expression of a subset of genes
regulated by estrogen receptor-alpha in MCF-7 breast cancer cells.
REFERENCE 2 (bases 1 to 9794)
AUTHORS Shimizu,A., Nakayama,H., Wang,P., Konig,C., Akino,T., Sandlund,J.,
Coma,S., Italiano,J.E. Jr., Mammoto,A., Bielenberg,D.R. and
Klagsbrun,M.
TITLE Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis
by multiple pathways including activation of RhoA, cathepsin B, and
cAMP-response element-binding protein
JOURNAL J. Biol. Chem. 288 (4), 2210-2222 (2013)
PUBMED 23195957
REMARK GeneRIF: Netrin-1 promotes glioblastoma cell invasiveness and
angiogenesis by multiple pathways including activation of RhoA,
cathepsin B, and cAMP-response element-binding protein
REFERENCE 3 (bases 1 to 9794)
AUTHORS Luo,Q., Viste,K., Urday-Zaa,J.C., Senthil Kumar,G., Tsai,W.W.,
Talai,A., Mayo,K.E., Montminy,M. and Radhakrishnan,I.
TITLE Mechanism of CREB recognition and coactivation by the
CREB-regulated transcriptional coactivator CRTC2
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 109 (51), 20865-20870 (2012)
PUBMED 23213254
REMARK GeneRIF: Mechanism of CREB recognition and coactivation by the
CREB-regulated transcriptional coactivator CRTC2
REFERENCE 4 (bases 1 to 9794)
AUTHORS Tan,X., Wang,S., Yang,B., Zhu,L., Yin,B., Chao,T., Zhao,J.,
Yuan,J., Qiang,B. and Peng,X.
TITLE The CREB-miR-9 negative feedback minicircuitry coordinates the
migration and proliferation of glioma cells
JOURNAL PLoS ONE 7 (11), E49570 (2012)
PUBMED 23185366
REMARK GeneRIF: CREB-miR-9 negative feedback minicircuitry coordinates the
migration and proliferation of glioma cells
REFERENCE 5 (bases 1 to 9794)
AUTHORS Li,Y., Shaw,C.A., Sheffer,I., Sule,N., Powell,S.Z., Dawson,B.,
Zaidi,S.N., Bucasas,K.L., Lupski,J.R., Wilhelmsen,K.C., Doody,R.
and Szigeti,K.
TITLE Integrated copy number and gene expression analysis detects a CREB1
association with Alzheimer's disease
JOURNAL Transl Psychiatry 2, E192 (2012)
PUBMED 23168992
REMARK GeneRIF: Copy number variation upstream of CREB1 was associated
with Alzheimer disease.
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 9794)
AUTHORS Meyer,T.E. and Habener,J.F.
TITLE Cyclic AMP response element binding protein CREB and modulator
protein CREM are products of distinct genes
JOURNAL Nucleic Acids Res. 20 (22), 6106 (1992)
PUBMED 1461747
REFERENCE 7 (bases 1 to 9794)
AUTHORS Zhao,L.J. and Giam,C.Z.
TITLE Human T-cell lymphotropic virus type I (HTLV-I) transcriptional
activator, Tax, enhances CREB binding to HTLV-I 21-base-pair
repeats by protein-protein interaction
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (15), 7070-7074 (1992)
PUBMED 1386673
REFERENCE 8 (bases 1 to 9794)
AUTHORS Rehfuss,R.P., Walton,K.M., Loriaux,M.M. and Goodman,R.H.
TITLE The cAMP-regulated enhancer-binding protein ATF-1 activates
transcription in response to cAMP-dependent protein kinase A
JOURNAL J. Biol. Chem. 266 (28), 18431-18434 (1991)
PUBMED 1655749
REFERENCE 9 (bases 1 to 9794)
AUTHORS Short,M.L., Manohar,C.F., Furtado,M.R., Ghadge,G.D., Wolinsky,S.M.,
Thimmapaya,B. and Jungmann,R.A.
TITLE Nucleotide and derived amino-acid sequences of the CRE-binding
proteins from rat C6 glioma and HeLa cells
JOURNAL Nucleic Acids Res. 19 (15), 4290 (1991)
PUBMED 1831258
REFERENCE 10 (bases 1 to 9794)
AUTHORS Waeber,G., Meyer,T.E., Hoeffler,J.P. and Habener,J.F.
TITLE Diversification of cyclic AMP-responsive enhancer binding
proteins-generated by alternative exon splicing
JOURNAL Trans. Assoc. Am. Physicians 103, 28-37 (1990)
PUBMED 1966745
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DC366797.1, BC010636.1,
AC079767.7 and AW205606.1.
This sequence is a reference standard in the RefSeqGene project.
On Dec 3, 2008 this sequence version replaced gi:22219460.
Summary: This gene encodes a transcription factor that is a member
of the leucine zipper family of DNA binding proteins. This protein
binds as a homodimer to the cAMP-responsive element, an octameric
palindrome. The protein is phosphorylated by several protein
kinases, and induces transcription of genes in response to hormonal
stimulation of the cAMP pathway. Alternate splicing of this gene
results in two transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2008].
Transcript Variant: This variant (B) encodes the longer isoform (B)
of this protein.
Sequence Note: The RefSeq transcript and protein were derived from
transcript and genomic sequence to make the sequence consistent
with the reference genome assembly. The genomic coordinates used
for the transcript record were based on alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC010636.1, X55545.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-157 DC366797.1 1-157
158-2719 BC010636.1 1-2562
2720-9298 AC079767.7 8455-15033
9299-9794 AW205606.1 1-496 c
FEATURES Location/Qualifiers
source 1..9794
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q34"
gene 1..9794
/gene="CREB1"
/gene_synonym="CREB"
/note="cAMP responsive element binding protein 1"
/db_xref="GeneID:1385"
/db_xref="HGNC:2345"
/db_xref="HPRD:00442"
/db_xref="MIM:123810"
exon 1..243
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
STS 166..940
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="Creb1"
/db_xref="UniSTS:527295"
variation 181
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050641"
exon 244..365
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
misc_feature 249..251
/gene="CREB1"
/gene_synonym="CREB"
/note="upstream in-frame stop codon"
CDS 252..1277
/gene="CREB1"
/gene_synonym="CREB"
/note="isoform B is encoded by transcript variant B;
cAMP-response element-binding protein-1; active
transcription factor CREB; transactivator protein; cyclic
AMP-responsive element-binding protein 1; CREB-1;
cAMP-responsive element-binding protein 1"
/codon_start=1
/product="cyclic AMP-responsive element-binding protein 1
isoform B"
/protein_id="NP_604391.1"
/db_xref="GI:19745184"
/db_xref="CCDS:CCDS2375.1"
/db_xref="GeneID:1385"
/db_xref="HGNC:2345"
/db_xref="HPRD:00442"
/db_xref="MIM:123810"
/translation="
MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQSSCKDLKRLFSGTQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD
"
misc_feature 549..551
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:06347"
misc_feature 582..584
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:06347"
misc_feature 606..608
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 612..614
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:06347"
misc_feature <618..704
/gene="CREB1"
/gene_synonym="CREB"
/note="pKID domain; Region: pKID; pfam02173"
/db_xref="CDD:145367"
misc_feature 636..638
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:05418"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by CaMK1, CaMK2, CaMK4, PKB/AKT1 or
PKB/AKT2, RPS6KA3, RPS6KA4, RPS6KA5 and SGK1; propagated
from UniProtKB/Swiss-Prot (P16220.2); phosphorylation
site"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:01261"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02092"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:03402"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:03403"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:04677"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:06789"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:08910"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:11882"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:04264"
misc_feature 648..650
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:12642"
misc_feature 1062..1064
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by HIPK2; propagated from
UniProtKB/Swiss-Prot (P16220.2); phosphorylation site"
misc_feature 1092..1274
/gene="CREB1"
/gene_synonym="CREB"
/note="bZIP transcription factor; Region: bZIP_1;
pfam00170"
/db_xref="CDD:201054"
misc_feature 1101..1178
/gene="CREB1"
/gene_synonym="CREB"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P16220.2);
Region: Basic motif (By similarity)"
misc_feature 1182..1247
/gene="CREB1"
/gene_synonym="CREB"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P16220.2);
Region: Leucine-zipper (By similarity)"
misc_feature 1191..1193
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="Required for binding TORCs; propagated from
UniProtKB/Swiss-Prot (P16220.2); other site"
variation 259..260
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="g"
/db_xref="dbSNP:35318842"
variation 273
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:367727829"
variation 318
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:56292136"
variation 326
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:370037055"
variation 354
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:114514847"
exon 366..512
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 388
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:143117860"
variation 407
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:140357947"
variation 430
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:374575266"
variation 434
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:35349697"
variation 467
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:78701038"
variation 475
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:376460743"
exon 513..554
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
exon 555..655
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 598
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:387906617"
exon 656..798
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 758
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:201642429"
exon 799..981
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 845
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:376739437"
variation 866
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:111280106"
variation 875
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:56020464"
variation 972
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:147363050"
exon 982..1132
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 1001
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:74338269"
variation 1031
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:370046152"
variation 1058
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:373274620"
exon 1133..9779
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 1154
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:145164313"
variation 1169
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:140407055"
variation 1199
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:113621918"
variation 1201
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:76312267"
variation 1236
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:113145794"
variation 1321
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:372883715"
variation 1322
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:375322973"
polyA_signal 1345..1350
/gene="CREB1"
/gene_synonym="CREB"
STS 1364..1465
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="D2S2634"
/db_xref="UniSTS:947"
polyA_site 1366
/gene="CREB1"
/gene_synonym="CREB"
variation 1494
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:192082921"
variation 1540
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:56267720"
STS 1558..2432
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="CREB1_v456"
/db_xref="UniSTS:277126"
variation 1616
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:182906174"
variation 1668
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:143587811"
variation 1717
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:75550279"
variation 1773
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:188411162"
variation 1815
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:191157228"
variation 1916
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:371836046"
STS 1927..2023
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="RH67919"
/db_xref="UniSTS:28279"
variation 2084
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:56390214"
variation 2086
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:55879019"
variation 2105
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:182205610"
variation 2107
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:372808746"
polyA_signal 2147..2152
/gene="CREB1"
/gene_synonym="CREB"
polyA_site 2176
/gene="CREB1"
/gene_synonym="CREB"
variation 2199
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:79271892"
variation 2222
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:187559873"
variation 2389
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:368510478"
variation 2399
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:192450396"
variation 2427
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:185867924"
variation 2437
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:56291091"
variation 2474
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:56299306"
variation 2568..2569
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ta"
/db_xref="dbSNP:374093740"
variation 2578
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:375850822"
variation 2706..2708
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aaa"
/db_xref="dbSNP:200878580"
variation 2706..2707
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aa"
/db_xref="dbSNP:143222694"
variation 2706
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aa"
/db_xref="dbSNP:10568689"
variation 2765
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:184610034"
variation 2788
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:73056958"
variation 2836
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:150397030"
variation 2948
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:138437655"
variation 3015
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:143910207"
variation 3039
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:146786929"
variation 3069
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:201051271"
variation 3070
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="a"
/db_xref="dbSNP:11319861"
variation 3070
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:199698025"
variation 3119
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:79736988"
variation 3155
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:76511710"
variation 3171
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:139198232"
variation 3214
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:56325368"
variation 3287
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:12998128"
variation 3373
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:188764041"
variation 3419
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:374925108"
variation 3434
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:143340162"
variation 3560
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:377363594"
variation 3746
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:180685015"
variation 3766
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:372887564"
variation 3786
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:78823096"
variation 3799
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:369543832"
variation 3909
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:35836086"
variation 4081
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:188447438"
variation 4366
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:371052022"
variation 4457..4458
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="atat"
/db_xref="dbSNP:71412422"
variation 4457
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:375493613"
variation 4458..4461
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="atat"
/db_xref="dbSNP:72442628"
variation 4458..4459
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="at"
/replace="atat"
/db_xref="dbSNP:71786143"
variation 4468..4469
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="at"
/db_xref="dbSNP:72062178"
variation 4482..4483
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tata"
/db_xref="dbSNP:71036937"
variation 4497
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:148160448"
variation 4887
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:182101766"
variation 5039
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:13029936"
variation 5041
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:114892556"
variation 5144
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:116076718"
variation 5207..5208
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tc"
/db_xref="dbSNP:34171849"
variation 5208..5209
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ct"
/db_xref="dbSNP:10559988"
variation 5209..5214
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tctgtt"
/db_xref="dbSNP:199601798"
variation 5209..5210
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ct"
/db_xref="dbSNP:72544077"
variation 5209
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:201988867"
variation 5210
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:201754017"
variation 5230
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:141652982"
variation 5265
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:150506251"
variation 5267
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:139870509"
variation 5273
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:2551928"
variation 5344..5347
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ttta"
/db_xref="dbSNP:139164200"
variation 5344
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ttta"
/db_xref="dbSNP:5838080"
variation 5347..5350
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="attt"
/db_xref="dbSNP:376057671"
variation 5347
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:200703008"
variation 5347
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="attt"
/db_xref="dbSNP:10559989"
variation 5349
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:200838888"
variation 5434
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:111992031"
variation 5440
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:187594841"
variation 5660
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:191527208"
variation 5701
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:181966687"
variation 5756..5760
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ctcaa"
/db_xref="dbSNP:375357358"
variation 5765
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:1806584"
variation 5861
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:1806585"
variation 5935
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:185366371"
variation 5948
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:56129159"
variation 6059
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:143220643"
variation 6072..6073
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="t"
/db_xref="dbSNP:35856558"
variation 6108
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:190175450"
variation 6128
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:146249401"
variation 6134
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ttaag"
/db_xref="dbSNP:112958608"
variation 6151..6152
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tg"
/db_xref="dbSNP:200579743"
variation 6204
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:139271055"
variation 6222
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:149927228"
variation 6299
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:111842669"
variation 6323
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:182658728"
variation 6523
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:377737239"
variation 6645
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:1045780"
variation 6715
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:149111106"
variation 6768
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:13386109"
variation 6924
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:186586133"
polyA_signal 6958..6963
/gene="CREB1"
/gene_synonym="CREB"
polyA_site 6987
/gene="CREB1"
/gene_synonym="CREB"
variation 7025
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:189904488"
variation 7073
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:183832672"
variation 7196
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:373213291"
variation 7254
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:12999688"
variation 7292
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:1045790"
variation 7307
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:115526431"
variation 7492
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:6785"
variation 7495
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:189094154"
variation 7580
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:192810631"
variation 7684
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:147657658"
variation 7967
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:2551929"
variation 7994
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:142438869"
variation 8058..8059
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="a"
/db_xref="dbSNP:376856014"
variation 8106
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:146501770"
variation 8120
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:139123873"
variation 8238..8240
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="caa"
/db_xref="dbSNP:371137073"
variation 8259
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:374059381"
variation 8290
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:140564236"
variation 8306
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:35371479"
variation 8359
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:185369978"
variation 8387
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:187039760"
variation 8409
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:370775575"
variation 8460
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:191720781"
variation 8540
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:55694411"
variation 8553..8557
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aactt"
/db_xref="dbSNP:138273242"
variation 8620
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:61058659"
variation 8633
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:150454556"
variation 8639
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:184271497"
STS 8657..8787
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="SGC35219"
/db_xref="UniSTS:61462"
variation 8679
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:2256941"
variation 8683
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:138348185"
variation 8709..8712
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aaga"
/db_xref="dbSNP:4025849"
variation 8713
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:75167578"
variation 8714..8715
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ag"
/db_xref="dbSNP:4025848"
variation 8753
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:116590105"
variation 8798
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:149629990"
variation 8825
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:369869267"
variation 8890..8892
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="acc"
/db_xref="dbSNP:147476972"
variation 8892..8894
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="cac"
/db_xref="dbSNP:368442759"
variation 8894
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:188266883"
variation 8970
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:181042336"
variation 8972
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:78913180"
variation 8978
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:185392351"
variation 8997
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:58914399"
variation 9024
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:368788833"
variation 9080
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:2551930"
variation 9139
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:190734638"
variation 9152
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:374469647"
variation 9241
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:181529395"
variation 9336
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:185814853"
variation 9491..9492
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tc"
/db_xref="dbSNP:142169610"
variation 9502
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:145940427"
variation 9669
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:190615978"
variation 9676
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:367769465"
variation 9745..9746
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="a"
/db_xref="dbSNP:374747042"
variation 9754
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:369125242"
ORIGIN
tgtttccgtgcgcggccgctgcgcactcggcactgggcggcgctggctggctccctggctgcggctcctcagtcggcggcggctgctgctgcctgtggcccgggcggctgggagaagcggagtgttggtgagtgacgcggcggaggtgtagtttgacgcggtgtgttacgtgggggagagaataaaactccagcgagatccgggccgtgaacgaaagcagtgacggaggagcttgtaccaccggtaactaaatgaccatggaatctggagccgagaaccagcagagtggagatgcagctgtaacagaagctgaaaaccaacaaatgacagttcaagcccagccacagattgccacattagcccaggtatctatgccagcagctcatgcaacatcatctgctcccaccgtaactctagtacagctgcccaatgggcagacagttcaagtccatggagtcattcaggcggcccagccatcagttattcagtctccacaagtccaaacagttcagtcttcctgtaaggacttaaaaagacttttctccggaacacagatttcaactattgcagaaagtgaagattcacaggagtcagtggatagtgtaactgattcccaaaagcgaagggaaattctttcaaggaggccttcctacaggaaaattttgaatgacttatcttctgatgcaccaggagtgccaaggattgaagaagagaagtctgaagaggagacttcagcacctgccatcaccactgtaacggtgccaactccaatttaccaaactagcagtggacagtatattgccattacccagggaggagcaatacagctggctaacaatggtaccgatggggtacagggcctgcaaacattaaccatgaccaatgcagcagccactcagccgggtactaccattctacagtatgcacagaccactgatggacagcagatcttagtgcccagcaaccaagttgttgttcaagctgcctctggagacgtacaaacataccagattcgcacagcacccactagcactattgcccctggagttgttatggcatcctccccagcacttcctacacagcctgctgaagaagcagcacgaaagagagaggtccgtctaatgaagaacagggaagcagctcgagagtgtcgtagaaagaagaaagaatatgtgaaatgtttagaaaacagagtggcagtgcttgaaaatcaaaacaagacattgattgaggagctaaaagcacttaaggacctttactgccacaaatcagattaatttgggatttaaattttcacctgttaaggtggaaaatggactggcttggccacaacctgaaagacaaaataaacattttattttctaaacatttctttttttctatgcgcaaaactgcctgaaagcaactacagaatttcattcatttgtgcttttgcattaaactgtgaatgttccaacacctgcctccacttctcccctcaagaaattttcaacgccaggaatcatgaagagacttctgcttttcaacccccaccctcctcaagaagtaataatttgtttacttgtaaattgatgggagaaatgaggaaaagaaaatctttttaaaaatgatttcaaggtttgtgctgagctccttgattgccttagggacagaattaccccagcctcttgagctgaagtaatgtgtgggccgcatgcataaagtaagtaaggtgcaatgaagaagtgttgattgccaaattgacatgttgtcacattctcattgtgaattatgtaaagttgttaagagacataccctctaaaaaagaactttagcatggtattgaaggaattagaaatgaatttggagtgctttttatgtatgttgtcttcttcaatactgaaaatttgtccttggttcttaaaagcattctgtactaatacagctcttccatagggcagttgttgcttcttaattcagttctgtatgtgttcaacatttttgaatacattaaaagaagtaaccaactgaacgacaaagcatggtatttgaattttaaattaaagcaaagtaaataaaagtacaaagcatattttagttagtactaaattcttagtaaaatgctgatcagtaaaccaatcccttgagttatataacaagatttttaaataaatgttattgtcctcaccttcaaaaatatttatattgtcactcatttacgtaaaaagatatttctaatttactgttgcccattgcacttacataccaccaccaagaaagccttcaagatgtcaaataaagcaaagtgatatatatttgtttatgaaatgttacatgtagaaaaatactgattttaaatattttccatattaacaatttaacagagaatctctagtgaattttttaaatgaaagaagttgtaaggatataaaaagtacagtgttagatgtgcacaaggaaagttattttcagacatatttgaatgactgctgtactgcaatatttggattgtcattcttacaaaacatttttttgttctcttgtaaaaagagtagttattagttctgctttagctttccaatatgctgtatagcctttgtcattttataattttaattcctgattaaaacagtctgtatttgtgtatatcatacattgttttcaataccacttttaattgttactcattttattcactaagctcgataaatctaacagttactcttaaaaaaaaaaaaaaaagactaaggtggattttaaaaattggaaactgacataatgttaggttataatttctcatttggagccgggcgcagtggctcacgcctgtaatcccagcactttgggaggccaaggtgggtggatcacctgtggtcaagagttcaagaccagcctggccatcatggtgaaaccccatctctactaaaaatacaaaaattagccaggcgtggtggctggcgcctgtaatcccagctactcaggaggttgaggcagcagaattgcttgaacccaggaggcagagggttgcagtgagccgagatagcaccattgcactccagcctgggcgactccatctcaaaaaataaaaataaaaaaaatgtctcatttgggaaggaaattccttttaaaaaagagttgagacacttagaaaactaatgttttatatttagtcaagagttatttaagaaagtcaagcttgtttaacaacaaaatatgaagatttaagtgttaattgctggatccattttaaaataagattttaattaacatttgtaaatggtatattttcgtttgtaacaaaccattgtcttttttcaaggatgaacagagtttatgaaggagcatcattctaagaattaagtgatgtagtctttatgtttggacagttcaccagattctcaagaaggctttcaaacaactataaagtttgatgtttgtcctgctgagctaatggggaaagttatagcataaaaattgtgtaaccgcatagatatgtcatttttaaaaactggtttaacagaaatcaagcaaagtcacaaatatgttcacaagttggaattatttattgagtcaaaatgtcgaatcgaacattttgaatgaagtaagtgttataaatgaaaaattgcctgatgtttagcagtttgtattctctaaagctttttttcaaaagttcaggctttctacttactgggaagttggtggtcctcttagtccctgataaatcaaggcaatcacattcatgtgagctggatgaatttataagttataaagaccttatccttcataccttgaggatgattgcactggttttgaagtcagttgcttaatgatgaggtgagaaatgtatcctgttgctaaatctgtcttagacccttggtgaaacttgaagatttcagtttataaagataaaatcaagcatcttttgtgcagttttctttttttaatgcaagaatggtggggaggtttgtttgtaagcatgaaactttgagaatctttattaagaaaatgacataatttttaaaaaccttgtagccaagaacatatgtggccacattaccagtaataaatgtttttctctttatattggccaaaagggaataaaaatgtcatcataggaatttgtacatatgctactgatttgcctagaaaatagcaagtttgatattgctcactttgcaaatatagggccatgtggcacttttatctataggacagattaataaaaatgaagtggggaggggtttatttttgatatattactcttatgagttttcaagctttgataatgtttaactgaaaagtggcttagaaagggctagatccaatgtgttcattattaaataattgctatcagatacaattttaagttcattctttttcaaactcaagtaccatattggcaaccataatattgtcataggtgctctcttcatttagatattcttggggggggtggcatttgtataatatatgtgtacatatatatatatatatatatatatacatacagtatataatctaaagctctgagagctcttaagtcaggaatgctgagtattatagtatattgaggtcagatgaaattttacatttttgtgtgttctgttgcattccttctggtagtttctatgactgcattactccagcactcatgattgattttatcttctaattttcttccaagtattttattttttattagttttctttggcttgatacttttaaatatgttactagtcacttgaaagcctctcccccaaaagtatttggtttgtatgctttgtctgtggcagctataacagtggtaagaacattttgaagatagctttttaaaggaaccactgattttttcaaaaatcatcctgggggaggaattttggcatttcatttgagcagggattttgtcagaaaatgtgttttgatggtaggtcagcagcagtgctagtctctgaaagcacaataccagtcaggcagcctatcccatcagatgtcatctggctgaagtttatctctgtctctcaggataaatccctgtaggacaaatccctactatcatttctaccttttggggtgacatgtggaatcatacaaaggcttaggaagaaatacgtttgtttaaaccaggatgctttacttacttgaagtgacttcaatctagatttcttttaatatttaacaaatttttaattctatgatcagccacagtcagctattaccataaattggtctctgtttattttgaagatcacggctgcttcattttgcaggattaagtagggctaatgtatcttaaagttaagatcttgaattaaagtgagttttagaaatagtgttacataccttttcagttgttttcaagaggctttatttttgttgcctttgtagccctgaaagctgttggtatattttttccctcatggacccaatagaaaagttgtatatttatttggattatatttacattctgtcctttgtaaatgtttggtgtaacttgcacttttttaaatgacccagtttgggtattagcaacttaagaaattccctcatcaagtaattctcaactttttagtctttctcctctcttcaaatcatgtgactttttaaatggaagtttttcattgattaaaatattttagcacctaaaagctagccttaaaaacagctgtaaaagaaaaacatcaggaaattagatatgactagcccagttaattaaaagacgggctcaaaccttgttttattctttttcatcttggatgaagattgaagggaaaataactcaagtgcataatatttattttcaatttttaatgagactttatcctcatcacaacattaatactgtacatagtatgccaaaatatccattaatttgtctagaatagtacaagactttttaaagcaattgtcctcacagagaccacatgtaatatactgaaatatgttcatttttaatggctttgttaacatcaaagaaatgctgcctaaatttgatttcagatgaggaaggagaaagtaaagtgtgcatagtaaggctgtaggtgaagagttgtgagataaatagttcactcagttgtacaaagcacaactagaactttttgttgggaggcttacatacatcttgaatattcttaatgtaataatgttgactattaagttggctacacagtcactgtatgtactaggaactggtttccttgacattctagaatcaatggctaggagaggcattaatctttgaggggctgaacatatcatgaagctgagtcagtatggaaaattttcaaataaacagggtgctgaagttccatctgtctcatctgcttatgataagttcttattgattagtgaatgtagcttaagcctttgtatgtgtcctcagggggcagaccgactttaagagggaccagataacgtttgaatggagggattatatttcaggtgttttagcttgaaatttattttttaaaaaaagaaaaatttaaaaaatatataaataaaatagaacaaagccggtgatgcaagttgatattataaacaggcagttttagcacagaaagaaaatactgacctgtctgcattctggtacggtgggtgcaggtcccagctgggtatgacatgatacatttttaattattctcaccagcaagtaaaaggaaaatgaacaatcttttggaattgtctttgaaaaggatcaaagagtaggaaattcacatttgacctaacattacttgcctatagaagtatggcatttccaagcttttgtctgaggagcatctcagagaagtgagagtaaatctgagttagcttaaaaattggtagggaggaagaaaatctctgcaaataatgattttatgtttgttggccaagtgaaatgatctatcattgtgtttgggaggttttattttcttatgtttttaaaattggtaaatgctttatagatgtatttttatccaagtgccactccaatttgtgtatgtaataaaattatttatattaaaagtgggaaataattgtcaacattttttttgagtatagatttattaggggtggcaaagaagagtgctagttagcagttttccatgtaaagttgtccttgactgatttgtccacatgtcagttgtaactcccccactccctgcaaaaggaattatttctaacccagatgtatcacttgaaactttttagaagcaaaataatcagggaagttcctagaaaggtgtttggctttttggtttttgagggttggggtaaagaagacttcccccacaactgtcagcacaaaacagggtattgatttttaactctgatgtttctattggagttgaatactaaataaataactataatgagggaaatacatttctaataaaattccctacattctagaaacatccctgttttaatttttttatctaaatctttttgtgctttatgtgtaaagaaaaaaatgtactgagttacaatgcattttattaacactatgtacataatagctgctttgtgttcagaatagtagcagttgctttgtatattaaagtgatccttgtgaatttgtgaaatattgtcataaagtgctttttcttactgtaatctttgtggtatcaactgtcataatgctctttttacacaaacatttatgtgcagtcacataaacatgcttttaaaaactctgtaagtctcttttttggggatgggatctctatattttgttgggttttttttgctagtagtgtgaagccatgttttattggacttaaagttacaatatattacaagcttgtgttggaaggcagcaaaactaattcagacaacaacatgtcttcagttactggatccctaattttcaggacaaaacctgtttttcaataagattgaacagtgcctatttgtggatttggagatgttactgtcaagatgactaatggagacatacgaccagctgtgtctgatgtcataaaacacgtgttcactgaaaggacaataagactatataccttctcaggtccccttgcaattctaaaactctgtgatcatataaattggaaggaaaggggaggggatatggttaatctttgcttaagctgtaagaataaaaaagttatctcctatactattaacttctgaaataagttctgagacgagacatctgaaaataagcagctgcattatttgtatgtttcttcactgccaagatgtgttcaagcctgctatacctgccattgtattggaaggcttaatgaatttcatttattttctgcaacaacgattacagaatttattgcacaaaatgagacattttgagagtgatattaattacatgagggacaataggcatgaactaggattgttctaagcaaatcggaatcgggtcaccctgccacgttcaggtgcttggaccttcaggaaaagattgcccatcttgtcatttgaccaggcactgaagtgacaagaccatccttgagaagtcacatccaaagataaaattctgatccatttctagttttagtgtttcgccactgaagacttaacatatgtcttttacactcaggttgcaaaacacaggcccaagacaaacttaacttctcccccaaatcttccttccgctggtttttccatctcgtaagtggtgccactatccatctgttaaattgtttaggggaaacctagaaaagcactaccttaatcagtgttatccttcttcttaactgtgcgtcctaatttctccacatctttcttaagtgcagtgaccaaaccggatgagaattctaacacgggcctgacatcaaatggaaaggaaggataatgtccaggagttggaatgttatccttgtttttaattaagatgcaattcacataaattaactttttaagtgaacaattaagtggtagtacatccacaatggtgtacaaccaccacttctatctagctccaaaacattctcatcactccaaaagtaaagtcccgttactctccattttctcctcccaccgcccttgtccctggcaaccaccaatctgcttcctgtttctttggatttacatccgggtatttcatgtgagactcatacactgtgtattacttctttcgtctagctttaatgtgttgttgaggttgatccattgtaacatgttatcactacttcattcctttttatagctaagtatactttttatagtaagtatgccattgtagatatataccacaagtttatcgattcatccagttgagttgtttctactgtttggctaatgttcatagtgctgttatgaatgttcgtgtacaagtatttgagtccgtgttttcaattatttggggtatatgcctgggagtggagttgctgggtcatgttgaaatcgcacatttaactttttgaggaactgtcaaactttccctcagcagctgtaccgttttaccttccaccattgatgtatgagggttccaatttctccacaccttcaccaacacttattttgccattttaaaaattatagccatcctcatgggtgtggtctctcattgtggttttgatttgcatttccctgattactaatgatgtggagcatcttttgttgtctttggccatctgcgtatcttctttgaagaaatgtctgttgaggtcctttgttcattgaaattttgttgttgggttctgagttccttatatattctgggtactaggcccttataatattttcgcctataagtttttgctttataatgtcctcattgttttcaaacttactttatgtaatatgtacacttctaaaaaaaagaaacatggaaaagggcaaactgtaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:1385 -> Molecular function: GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] evidence: IDA
GeneID:1385 -> Molecular function: GO:0001102 [RNA polymerase II activating transcription factor binding] evidence: IPI
GeneID:1385 -> Molecular function: GO:0001190 [RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription] evidence: IDA
GeneID:1385 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:1385 -> Molecular function: GO:0003705 [RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:1385 -> Molecular function: GO:0003712 [transcription cofactor activity] evidence: TAS
GeneID:1385 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:1385 -> Molecular function: GO:0035497 [cAMP response element binding] evidence: IDA
GeneID:1385 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0006468 [protein phosphorylation] evidence: IDA
GeneID:1385 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
GeneID:1385 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0007202 [activation of phospholipase C activity] evidence: TAS
GeneID:1385 -> Biological process: GO:0007219 [Notch signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0007268 [synaptic transmission] evidence: TAS
GeneID:1385 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
GeneID:1385 -> Biological process: GO:0007595 [lactation] evidence: IEA
GeneID:1385 -> Biological process: GO:0008361 [regulation of cell size] evidence: IEA
GeneID:1385 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0010033 [response to organic substance] evidence: IDA
GeneID:1385 -> Biological process: GO:0010944 [negative regulation of transcription by competitive promoter binding] evidence: IDA
GeneID:1385 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
GeneID:1385 -> Biological process: GO:0021983 [pituitary gland development] evidence: IEA
GeneID:1385 -> Biological process: GO:0033363 [secretory granule organization] evidence: IEA
GeneID:1385 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0040018 [positive regulation of multicellular organism growth] evidence: IEA
GeneID:1385 -> Biological process: GO:0042493 [response to drug] evidence: IEA
GeneID:1385 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:1385 -> Biological process: GO:0045600 [positive regulation of fat cell differentiation] evidence: ISS
GeneID:1385 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: ISS
GeneID:1385 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:1385 -> Biological process: GO:0046887 [positive regulation of hormone secretion] evidence: IEA
GeneID:1385 -> Biological process: GO:0046889 [positive regulation of lipid biosynthetic process] evidence: ISS
GeneID:1385 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: TAS
GeneID:1385 -> Biological process: GO:0050821 [protein stabilization] evidence: ISS
GeneID:1385 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: TAS
GeneID:1385 -> Biological process: GO:0060430 [lung saccule development] evidence: IEA
GeneID:1385 -> Biological process: GO:0060509 [Type I pneumocyte differentiation] evidence: IEA
GeneID:1385 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:1385 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:1385 -> Cellular component: GO:0005667 [transcription factor complex] evidence: IEA
GeneID:1385 -> Cellular component: GO:0005719 [nuclear euchromatin] evidence: IDA
GeneID:1385 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
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