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2025-05-09 18:49:26, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_004379 9752 bp mRNA linear PRI 26-MAY-2013
DEFINITION Homo sapiens cAMP responsive element binding protein 1 (CREB1),
transcript variant A, mRNA.
ACCESSION NM_004379
VERSION NM_004379.3 GI:215490111
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 9752)
AUTHORS Hoang,T., Fenne,I.S., Madsen,A., Bozickovic,O., Johannessen,M.,
Bergsvag,M., Lien,E.A., Stallcup,M.R., Sagen,J.V., Moens,U. and
Mellgren,G.
TITLE cAMP response element-binding protein interacts with and stimulates
the proteasomal degradation of the nuclear receptor coactivator
GRIP1
JOURNAL Endocrinology 154 (4), 1513-1527 (2013)
PUBMED 23462962
REMARK GeneRIF: cAMP response element-binding protein (CREB) downregulates
GRIP1 and is necessary for the PKA-stimulated degradation of GRIP1,
which leads to changes in the expression of a subset of genes
regulated by estrogen receptor-alpha in MCF-7 breast cancer cells.
REFERENCE 2 (bases 1 to 9752)
AUTHORS Shimizu,A., Nakayama,H., Wang,P., Konig,C., Akino,T., Sandlund,J.,
Coma,S., Italiano,J.E. Jr., Mammoto,A., Bielenberg,D.R. and
Klagsbrun,M.
TITLE Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis
by multiple pathways including activation of RhoA, cathepsin B, and
cAMP-response element-binding protein
JOURNAL J. Biol. Chem. 288 (4), 2210-2222 (2013)
PUBMED 23195957
REMARK GeneRIF: Netrin-1 promotes glioblastoma cell invasiveness and
angiogenesis by multiple pathways including activation of RhoA,
cathepsin B, and cAMP-response element-binding protein
REFERENCE 3 (bases 1 to 9752)
AUTHORS Luo,Q., Viste,K., Urday-Zaa,J.C., Senthil Kumar,G., Tsai,W.W.,
Talai,A., Mayo,K.E., Montminy,M. and Radhakrishnan,I.
TITLE Mechanism of CREB recognition and coactivation by the
CREB-regulated transcriptional coactivator CRTC2
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 109 (51), 20865-20870 (2012)
PUBMED 23213254
REMARK GeneRIF: Mechanism of CREB recognition and coactivation by the
CREB-regulated transcriptional coactivator CRTC2
REFERENCE 4 (bases 1 to 9752)
AUTHORS Tan,X., Wang,S., Yang,B., Zhu,L., Yin,B., Chao,T., Zhao,J.,
Yuan,J., Qiang,B. and Peng,X.
TITLE The CREB-miR-9 negative feedback minicircuitry coordinates the
migration and proliferation of glioma cells
JOURNAL PLoS ONE 7 (11), E49570 (2012)
PUBMED 23185366
REMARK GeneRIF: CREB-miR-9 negative feedback minicircuitry coordinates the
migration and proliferation of glioma cells
REFERENCE 5 (bases 1 to 9752)
AUTHORS Li,Y., Shaw,C.A., Sheffer,I., Sule,N., Powell,S.Z., Dawson,B.,
Zaidi,S.N., Bucasas,K.L., Lupski,J.R., Wilhelmsen,K.C., Doody,R.
and Szigeti,K.
TITLE Integrated copy number and gene expression analysis detects a CREB1
association with Alzheimer's disease
JOURNAL Transl Psychiatry 2, E192 (2012)
PUBMED 23168992
REMARK GeneRIF: Copy number variation upstream of CREB1 was associated
with Alzheimer disease.
Publication Status: Online-Only
REFERENCE 6 (bases 1 to 9752)
AUTHORS Meyer,T.E. and Habener,J.F.
TITLE Cyclic AMP response element binding protein CREB and modulator
protein CREM are products of distinct genes
JOURNAL Nucleic Acids Res. 20 (22), 6106 (1992)
PUBMED 1461747
REFERENCE 7 (bases 1 to 9752)
AUTHORS Zhao,L.J. and Giam,C.Z.
TITLE Human T-cell lymphotropic virus type I (HTLV-I) transcriptional
activator, Tax, enhances CREB binding to HTLV-I 21-base-pair
repeats by protein-protein interaction
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (15), 7070-7074 (1992)
PUBMED 1386673
REFERENCE 8 (bases 1 to 9752)
AUTHORS Rehfuss,R.P., Walton,K.M., Loriaux,M.M. and Goodman,R.H.
TITLE The cAMP-regulated enhancer-binding protein ATF-1 activates
transcription in response to cAMP-dependent protein kinase A
JOURNAL J. Biol. Chem. 266 (28), 18431-18434 (1991)
PUBMED 1655749
REFERENCE 9 (bases 1 to 9752)
AUTHORS Short,M.L., Manohar,C.F., Furtado,M.R., Ghadge,G.D., Wolinsky,S.M.,
Thimmapaya,B. and Jungmann,R.A.
TITLE Nucleotide and derived amino-acid sequences of the CRE-binding
proteins from rat C6 glioma and HeLa cells
JOURNAL Nucleic Acids Res. 19 (15), 4290 (1991)
PUBMED 1831258
REFERENCE 10 (bases 1 to 9752)
AUTHORS Waeber,G., Meyer,T.E., Hoeffler,J.P. and Habener,J.F.
TITLE Diversification of cyclic AMP-responsive enhancer binding
proteins-generated by alternative exon splicing
JOURNAL Trans. Assoc. Am. Physicians 103, 28-37 (1990)
PUBMED 1966745
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DC366797.1, BC095407.1,
AC079767.7 and AW205606.1.
On Dec 3, 2008 this sequence version replaced gi:22219459.
Summary: This gene encodes a transcription factor that is a member
of the leucine zipper family of DNA binding proteins. This protein
binds as a homodimer to the cAMP-responsive element, an octameric
palindrome. The protein is phosphorylated by several protein
kinases, and induces transcription of genes in response to hormonal
stimulation of the cAMP pathway. Alternate splicing of this gene
results in two transcript variants encoding different isoforms.
[provided by RefSeq, Jul 2008].
Transcript Variant: This variant (A) lacks an in-frame exon in the
coding region, compared to variant B. Isoform A is shorter compared
to isoform B.
Sequence Note: The RefSeq transcript and protein were derived from
transcript and genomic sequence to make the sequence consistent
with the reference genome assembly. The genomic coordinates used
for the transcript record were based on alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC095407.1, M27691.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-56 DC366797.1 1-56
57-2661 BC095407.1 1-2605
2662-9256 AC079767.7 8439-15033
9257-9752 AW205606.1 1-496 c
FEATURES Location/Qualifiers
source 1..9752
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q34"
gene 1..9752
/gene="CREB1"
/gene_synonym="CREB"
/note="cAMP responsive element binding protein 1"
/db_xref="GeneID:1385"
/db_xref="HGNC:2345"
/db_xref="HPRD:00442"
/db_xref="MIM:123810"
exon 1..243
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
STS 166..898
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="Creb1"
/db_xref="UniSTS:527295"
variation 181
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050641"
exon 244..365
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
misc_feature 249..251
/gene="CREB1"
/gene_synonym="CREB"
/note="upstream in-frame stop codon"
CDS 252..1235
/gene="CREB1"
/gene_synonym="CREB"
/note="isoform A is encoded by transcript variant A;
cAMP-response element-binding protein-1; active
transcription factor CREB; transactivator protein; cyclic
AMP-responsive element-binding protein 1; CREB-1;
cAMP-responsive element-binding protein 1"
/codon_start=1
/product="cyclic AMP-responsive element-binding protein 1
isoform A"
/protein_id="NP_004370.1"
/db_xref="GI:4758054"
/db_xref="CCDS:CCDS2374.1"
/db_xref="GeneID:1385"
/db_xref="HGNC:2345"
/db_xref="HPRD:00442"
/db_xref="MIM:123810"
/translation="
MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD
"
misc_feature 540..542
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:06347"
misc_feature 570..572
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:06347"
misc_feature <576..662
/gene="CREB1"
/gene_synonym="CREB"
/note="pKID domain; Region: pKID; pfam02173"
/db_xref="CDD:145367"
misc_feature 594..596
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:05418"
misc_feature 606..608
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 606..608
/gene="CREB1"
/gene_synonym="CREB"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:04264"
misc_feature 1050..1232
/gene="CREB1"
/gene_synonym="CREB"
/note="bZIP transcription factor; Region: bZIP_1;
pfam00170"
/db_xref="CDD:201054"
variation 259..260
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="g"
/db_xref="dbSNP:35318842"
variation 273
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:367727829"
variation 318
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:56292136"
variation 326
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:370037055"
variation 354
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:114514847"
exon 366..512
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 388
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:143117860"
variation 407
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:140357947"
variation 430
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:374575266"
variation 434
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:35349697"
variation 467
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:78701038"
variation 475
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:376460743"
exon 513..613
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 556
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:387906617"
exon 614..756
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 716
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:201642429"
exon 757..939
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 803
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:376739437"
variation 824
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:111280106"
variation 833
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:56020464"
variation 930
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:147363050"
exon 940..1090
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 959
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:74338269"
variation 989
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:370046152"
variation 1016
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:373274620"
exon 1091..9737
/gene="CREB1"
/gene_synonym="CREB"
/inference="alignment:Splign:1.39.8"
variation 1112
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:145164313"
variation 1127
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:140407055"
variation 1157
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:113621918"
variation 1159
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:76312267"
variation 1194
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:113145794"
variation 1279
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:372883715"
variation 1280
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:375322973"
polyA_signal 1303..1308
/gene="CREB1"
/gene_synonym="CREB"
STS 1322..1423
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="D2S2634"
/db_xref="UniSTS:947"
polyA_site 1349
/gene="CREB1"
/gene_synonym="CREB"
variation 1452
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:192082921"
variation 1498
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:56267720"
STS 1516..2390
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="CREB1_v456"
/db_xref="UniSTS:277126"
variation 1574
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:182906174"
variation 1626
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:143587811"
variation 1675
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:75550279"
variation 1731
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:188411162"
variation 1773
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:191157228"
variation 1874
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:371836046"
STS 1885..1981
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="RH67919"
/db_xref="UniSTS:28279"
variation 2042
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:56390214"
variation 2044
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:55879019"
variation 2063
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:182205610"
variation 2065
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:372808746"
polyA_signal 2105..2110
/gene="CREB1"
/gene_synonym="CREB"
polyA_site 2134
/gene="CREB1"
/gene_synonym="CREB"
variation 2157
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:79271892"
variation 2180
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:187559873"
variation 2347
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:368510478"
variation 2357
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:192450396"
variation 2385
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:185867924"
variation 2395
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:56291091"
variation 2432
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:56299306"
variation 2526..2527
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ta"
/db_xref="dbSNP:374093740"
variation 2536
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:375850822"
variation 2664..2666
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aaa"
/db_xref="dbSNP:200878580"
variation 2664..2665
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aa"
/db_xref="dbSNP:143222694"
variation 2664
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aa"
/db_xref="dbSNP:10568689"
variation 2723
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:184610034"
variation 2746
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:73056958"
variation 2794
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:150397030"
variation 2906
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:138437655"
variation 2973
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:143910207"
variation 2997
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:146786929"
variation 3027
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:201051271"
variation 3028
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="a"
/db_xref="dbSNP:11319861"
variation 3028
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:199698025"
variation 3077
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:79736988"
variation 3113
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:76511710"
variation 3129
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:139198232"
variation 3172
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:56325368"
variation 3245
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:12998128"
variation 3331
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:188764041"
variation 3377
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:374925108"
variation 3392
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:143340162"
variation 3518
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:377363594"
variation 3704
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:180685015"
variation 3724
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:372887564"
variation 3744
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:78823096"
variation 3757
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:369543832"
variation 3867
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:35836086"
variation 4039
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:188447438"
variation 4324
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:371052022"
variation 4415..4416
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="atat"
/db_xref="dbSNP:71412422"
variation 4415
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:375493613"
variation 4416..4419
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="atat"
/db_xref="dbSNP:72442628"
variation 4416..4417
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="at"
/replace="atat"
/db_xref="dbSNP:71786143"
variation 4426..4427
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="at"
/db_xref="dbSNP:72062178"
variation 4440..4441
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tata"
/db_xref="dbSNP:71036937"
variation 4455
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:148160448"
variation 4845
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:182101766"
variation 4997
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:13029936"
variation 4999
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:114892556"
variation 5102
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:116076718"
variation 5165..5166
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tc"
/db_xref="dbSNP:34171849"
variation 5166..5167
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ct"
/db_xref="dbSNP:10559988"
variation 5167..5172
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tctgtt"
/db_xref="dbSNP:199601798"
variation 5167..5168
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ct"
/db_xref="dbSNP:72544077"
variation 5167
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:201988867"
variation 5168
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:201754017"
variation 5188
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:141652982"
variation 5223
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:150506251"
variation 5225
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:139870509"
variation 5231
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:2551928"
variation 5302..5305
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ttta"
/db_xref="dbSNP:139164200"
variation 5302
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ttta"
/db_xref="dbSNP:5838080"
variation 5305..5308
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="attt"
/db_xref="dbSNP:376057671"
variation 5305
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:200703008"
variation 5305
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="attt"
/db_xref="dbSNP:10559989"
variation 5307
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:200838888"
variation 5392
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:111992031"
variation 5398
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:187594841"
variation 5618
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="g"
/db_xref="dbSNP:191527208"
variation 5659
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:181966687"
variation 5714..5718
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ctcaa"
/db_xref="dbSNP:375357358"
variation 5723
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:1806584"
variation 5819
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:1806585"
variation 5893
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:185366371"
variation 5906
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:56129159"
variation 6017
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:143220643"
variation 6030..6031
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="t"
/db_xref="dbSNP:35856558"
variation 6066
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:190175450"
variation 6086
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:146249401"
variation 6092
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ttaag"
/db_xref="dbSNP:112958608"
variation 6109..6110
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tg"
/db_xref="dbSNP:200579743"
variation 6162
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:139271055"
variation 6180
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:149927228"
variation 6257
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:111842669"
variation 6281
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:182658728"
variation 6481
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:377737239"
variation 6603
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:1045780"
variation 6673
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:149111106"
variation 6726
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:13386109"
variation 6882
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:186586133"
polyA_signal 6916..6921
/gene="CREB1"
/gene_synonym="CREB"
polyA_site 6945
/gene="CREB1"
/gene_synonym="CREB"
variation 6983
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:189904488"
variation 7031
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:183832672"
variation 7154
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:373213291"
variation 7212
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:12999688"
variation 7250
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:1045790"
variation 7265
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:115526431"
variation 7450
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:6785"
variation 7453
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:189094154"
variation 7538
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:192810631"
variation 7642
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:147657658"
variation 7925
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:2551929"
variation 7952
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:142438869"
variation 8016..8017
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="a"
/db_xref="dbSNP:376856014"
variation 8064
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:146501770"
variation 8078
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:139123873"
variation 8196..8198
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="caa"
/db_xref="dbSNP:371137073"
variation 8217
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:374059381"
variation 8248
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:140564236"
variation 8264
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:35371479"
variation 8317
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:185369978"
variation 8345
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:187039760"
variation 8367
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:370775575"
variation 8418
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:191720781"
variation 8498
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:55694411"
variation 8511..8515
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aactt"
/db_xref="dbSNP:138273242"
variation 8578
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:61058659"
variation 8591
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:150454556"
variation 8597
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:184271497"
STS 8615..8745
/gene="CREB1"
/gene_synonym="CREB"
/standard_name="SGC35219"
/db_xref="UniSTS:61462"
variation 8637
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:2256941"
variation 8641
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:138348185"
variation 8667..8670
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="aaga"
/db_xref="dbSNP:4025849"
variation 8671
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:75167578"
variation 8672..8673
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="ag"
/db_xref="dbSNP:4025848"
variation 8711
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:116590105"
variation 8756
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:149629990"
variation 8783
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:369869267"
variation 8848..8850
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="acc"
/db_xref="dbSNP:147476972"
variation 8850..8852
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="cac"
/db_xref="dbSNP:368442759"
variation 8852
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:188266883"
variation 8928
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:181042336"
variation 8930
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:78913180"
variation 8936
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:185392351"
variation 8955
/gene="CREB1"
/gene_synonym="CREB"
/replace="g"
/replace="t"
/db_xref="dbSNP:58914399"
variation 8982
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:368788833"
variation 9038
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:2551930"
variation 9097
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="t"
/db_xref="dbSNP:190734638"
variation 9110
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:374469647"
variation 9199
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:181529395"
variation 9294
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="c"
/db_xref="dbSNP:185814853"
variation 9449..9450
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="tc"
/db_xref="dbSNP:142169610"
variation 9460
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:145940427"
variation 9627
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:190615978"
variation 9634
/gene="CREB1"
/gene_synonym="CREB"
/replace="c"
/replace="t"
/db_xref="dbSNP:367769465"
variation 9703..9704
/gene="CREB1"
/gene_synonym="CREB"
/replace=""
/replace="a"
/db_xref="dbSNP:374747042"
variation 9712
/gene="CREB1"
/gene_synonym="CREB"
/replace="a"
/replace="g"
/db_xref="dbSNP:369125242"
ORIGIN
tgtttccgtgcgcggccgctgcgcactcggcactgggcggcgctggctggctccctggctgcggctcctcagtcggcggcggctgctgctgcctgtggcccgggcggctgggagaagcggagtgttggtgagtgacgcggcggaggtgtagtttgacgcggtgtgttacgtgggggagagaataaaactccagcgagatccgggccgtgaacgaaagcagtgacggaggagcttgtaccaccggtaactaaatgaccatggaatctggagccgagaaccagcagagtggagatgcagctgtaacagaagctgaaaaccaacaaatgacagttcaagcccagccacagattgccacattagcccaggtatctatgccagcagctcatgcaacatcatctgctcccaccgtaactctagtacagctgcccaatgggcagacagttcaagtccatggagtcattcaggcggcccagccatcagttattcagtctccacaagtccaaacagttcagatttcaactattgcagaaagtgaagattcacaggagtcagtggatagtgtaactgattcccaaaagcgaagggaaattctttcaaggaggccttcctacaggaaaattttgaatgacttatcttctgatgcaccaggagtgccaaggattgaagaagagaagtctgaagaggagacttcagcacctgccatcaccactgtaacggtgccaactccaatttaccaaactagcagtggacagtatattgccattacccagggaggagcaatacagctggctaacaatggtaccgatggggtacagggcctgcaaacattaaccatgaccaatgcagcagccactcagccgggtactaccattctacagtatgcacagaccactgatggacagcagatcttagtgcccagcaaccaagttgttgttcaagctgcctctggagacgtacaaacataccagattcgcacagcacccactagcactattgcccctggagttgttatggcatcctccccagcacttcctacacagcctgctgaagaagcagcacgaaagagagaggtccgtctaatgaagaacagggaagcagctcgagagtgtcgtagaaagaagaaagaatatgtgaaatgtttagaaaacagagtggcagtgcttgaaaatcaaaacaagacattgattgaggagctaaaagcacttaaggacctttactgccacaaatcagattaatttgggatttaaattttcacctgttaaggtggaaaatggactggcttggccacaacctgaaagacaaaataaacattttattttctaaacatttctttttttctatgcgcaaaactgcctgaaagcaactacagaatttcattcatttgtgcttttgcattaaactgtgaatgttccaacacctgcctccacttctcccctcaagaaattttcaacgccaggaatcatgaagagacttctgcttttcaacccccaccctcctcaagaagtaataatttgtttacttgtaaattgatgggagaaatgaggaaaagaaaatctttttaaaaatgatttcaaggtttgtgctgagctccttgattgccttagggacagaattaccccagcctcttgagctgaagtaatgtgtgggccgcatgcataaagtaagtaaggtgcaatgaagaagtgttgattgccaaattgacatgttgtcacattctcattgtgaattatgtaaagttgttaagagacataccctctaaaaaagaactttagcatggtattgaaggaattagaaatgaatttggagtgctttttatgtatgttgtcttcttcaatactgaaaatttgtccttggttcttaaaagcattctgtactaatacagctcttccatagggcagttgttgcttcttaattcagttctgtatgtgttcaacatttttgaatacattaaaagaagtaaccaactgaacgacaaagcatggtatttgaattttaaattaaagcaaagtaaataaaagtacaaagcatattttagttagtactaaattcttagtaaaatgctgatcagtaaaccaatcccttgagttatataacaagatttttaaataaatgttattgtcctcaccttcaaaaatatttatattgtcactcatttacgtaaaaagatatttctaatttactgttgcccattgcacttacataccaccaccaagaaagccttcaagatgtcaaataaagcaaagtgatatatatttgtttatgaaatgttacatgtagaaaaatactgattttaaatattttccatattaacaatttaacagagaatctctagtgaattttttaaatgaaagaagttgtaaggatataaaaagtacagtgttagatgtgcacaaggaaagttattttcagacatatttgaatgactgctgtactgcaatatttggattgtcattcttacaaaacatttttttgttctcttgtaaaaagagtagttattagttctgctttagctttccaatatgctgtatagcctttgtcattttataattttaattcctgattaaaacagtctgtatttgtgtatatcatacattgttttcaataccacttttaattgttactcattttattcactaagctcgataaatctaacagttactcttaaaaaaaaaaaaaaaagactaaggtggattttaaaaattggaaactgacataatgttaggttataatttctcatttggagccgggcgcagtggctcacgcctgtaatcccagcactttgggaggccaaggtgggtggatcacctgtggtcaagagttcaagaccagcctggccatcatggtgaaaccccatctctactaaaaatacaaaaattagccaggcgtggtggctggcgcctgtaatcccagctactcaggaggttgaggcagcagaattgcttgaacccaggaggcagagggttgcagtgagccgagatagcaccattgcactccagcctgggcgactccatctcaaaaaataaaaataaaaaaaatgtctcatttgggaaggaaattccttttaaaaaagagttgagacacttagaaaactaatgttttatatttagtcaagagttatttaagaaagtcaagcttgtttaacaacaaaatatgaagatttaagtgttaattgctggatccattttaaaataagattttaattaacatttgtaaatggtatattttcgtttgtaacaaaccattgtcttttttcaaggatgaacagagtttatgaaggagcatcattctaagaattaagtgatgtagtctttatgtttggacagttcaccagattctcaagaaggctttcaaacaactataaagtttgatgtttgtcctgctgagctaatggggaaagttatagcataaaaattgtgtaaccgcatagatatgtcatttttaaaaactggtttaacagaaatcaagcaaagtcacaaatatgttcacaagttggaattatttattgagtcaaaatgtcgaatcgaacattttgaatgaagtaagtgttataaatgaaaaattgcctgatgtttagcagtttgtattctctaaagctttttttcaaaagttcaggctttctacttactgggaagttggtggtcctcttagtccctgataaatcaaggcaatcacattcatgtgagctggatgaatttataagttataaagaccttatccttcataccttgaggatgattgcactggttttgaagtcagttgcttaatgatgaggtgagaaatgtatcctgttgctaaatctgtcttagacccttggtgaaacttgaagatttcagtttataaagataaaatcaagcatcttttgtgcagttttctttttttaatgcaagaatggtggggaggtttgtttgtaagcatgaaactttgagaatctttattaagaaaatgacataatttttaaaaaccttgtagccaagaacatatgtggccacattaccagtaataaatgtttttctctttatattggccaaaagggaataaaaatgtcatcataggaatttgtacatatgctactgatttgcctagaaaatagcaagtttgatattgctcactttgcaaatatagggccatgtggcacttttatctataggacagattaataaaaatgaagtggggaggggtttatttttgatatattactcttatgagttttcaagctttgataatgtttaactgaaaagtggcttagaaagggctagatccaatgtgttcattattaaataattgctatcagatacaattttaagttcattctttttcaaactcaagtaccatattggcaaccataatattgtcataggtgctctcttcatttagatattcttggggggggtggcatttgtataatatatgtgtacatatatatatatatatatatatatacatacagtatataatctaaagctctgagagctcttaagtcaggaatgctgagtattatagtatattgaggtcagatgaaattttacatttttgtgtgttctgttgcattccttctggtagtttctatgactgcattactccagcactcatgattgattttatcttctaattttcttccaagtattttattttttattagttttctttggcttgatacttttaaatatgttactagtcacttgaaagcctctcccccaaaagtatttggtttgtatgctttgtctgtggcagctataacagtggtaagaacattttgaagatagctttttaaaggaaccactgattttttcaaaaatcatcctgggggaggaattttggcatttcatttgagcagggattttgtcagaaaatgtgttttgatggtaggtcagcagcagtgctagtctctgaaagcacaataccagtcaggcagcctatcccatcagatgtcatctggctgaagtttatctctgtctctcaggataaatccctgtaggacaaatccctactatcatttctaccttttggggtgacatgtggaatcatacaaaggcttaggaagaaatacgtttgtttaaaccaggatgctttacttacttgaagtgacttcaatctagatttcttttaatatttaacaaatttttaattctatgatcagccacagtcagctattaccataaattggtctctgtttattttgaagatcacggctgcttcattttgcaggattaagtagggctaatgtatcttaaagttaagatcttgaattaaagtgagttttagaaatagtgttacataccttttcagttgttttcaagaggctttatttttgttgcctttgtagccctgaaagctgttggtatattttttccctcatggacccaatagaaaagttgtatatttatttggattatatttacattctgtcctttgtaaatgtttggtgtaacttgcacttttttaaatgacccagtttgggtattagcaacttaagaaattccctcatcaagtaattctcaactttttagtctttctcctctcttcaaatcatgtgactttttaaatggaagtttttcattgattaaaatattttagcacctaaaagctagccttaaaaacagctgtaaaagaaaaacatcaggaaattagatatgactagcccagttaattaaaagacgggctcaaaccttgttttattctttttcatcttggatgaagattgaagggaaaataactcaagtgcataatatttattttcaatttttaatgagactttatcctcatcacaacattaatactgtacatagtatgccaaaatatccattaatttgtctagaatagtacaagactttttaaagcaattgtcctcacagagaccacatgtaatatactgaaatatgttcatttttaatggctttgttaacatcaaagaaatgctgcctaaatttgatttcagatgaggaaggagaaagtaaagtgtgcatagtaaggctgtaggtgaagagttgtgagataaatagttcactcagttgtacaaagcacaactagaactttttgttgggaggcttacatacatcttgaatattcttaatgtaataatgttgactattaagttggctacacagtcactgtatgtactaggaactggtttccttgacattctagaatcaatggctaggagaggcattaatctttgaggggctgaacatatcatgaagctgagtcagtatggaaaattttcaaataaacagggtgctgaagttccatctgtctcatctgcttatgataagttcttattgattagtgaatgtagcttaagcctttgtatgtgtcctcagggggcagaccgactttaagagggaccagataacgtttgaatggagggattatatttcaggtgttttagcttgaaatttattttttaaaaaaagaaaaatttaaaaaatatataaataaaatagaacaaagccggtgatgcaagttgatattataaacaggcagttttagcacagaaagaaaatactgacctgtctgcattctggtacggtgggtgcaggtcccagctgggtatgacatgatacatttttaattattctcaccagcaagtaaaaggaaaatgaacaatcttttggaattgtctttgaaaaggatcaaagagtaggaaattcacatttgacctaacattacttgcctatagaagtatggcatttccaagcttttgtctgaggagcatctcagagaagtgagagtaaatctgagttagcttaaaaattggtagggaggaagaaaatctctgcaaataatgattttatgtttgttggccaagtgaaatgatctatcattgtgtttgggaggttttattttcttatgtttttaaaattggtaaatgctttatagatgtatttttatccaagtgccactccaatttgtgtatgtaataaaattatttatattaaaagtgggaaataattgtcaacattttttttgagtatagatttattaggggtggcaaagaagagtgctagttagcagttttccatgtaaagttgtccttgactgatttgtccacatgtcagttgtaactcccccactccctgcaaaaggaattatttctaacccagatgtatcacttgaaactttttagaagcaaaataatcagggaagttcctagaaaggtgtttggctttttggtttttgagggttggggtaaagaagacttcccccacaactgtcagcacaaaacagggtattgatttttaactctgatgtttctattggagttgaatactaaataaataactataatgagggaaatacatttctaataaaattccctacattctagaaacatccctgttttaatttttttatctaaatctttttgtgctttatgtgtaaagaaaaaaatgtactgagttacaatgcattttattaacactatgtacataatagctgctttgtgttcagaatagtagcagttgctttgtatattaaagtgatccttgtgaatttgtgaaatattgtcataaagtgctttttcttactgtaatctttgtggtatcaactgtcataatgctctttttacacaaacatttatgtgcagtcacataaacatgcttttaaaaactctgtaagtctcttttttggggatgggatctctatattttgttgggttttttttgctagtagtgtgaagccatgttttattggacttaaagttacaatatattacaagcttgtgttggaaggcagcaaaactaattcagacaacaacatgtcttcagttactggatccctaattttcaggacaaaacctgtttttcaataagattgaacagtgcctatttgtggatttggagatgttactgtcaagatgactaatggagacatacgaccagctgtgtctgatgtcataaaacacgtgttcactgaaaggacaataagactatataccttctcaggtccccttgcaattctaaaactctgtgatcatataaattggaaggaaaggggaggggatatggttaatctttgcttaagctgtaagaataaaaaagttatctcctatactattaacttctgaaataagttctgagacgagacatctgaaaataagcagctgcattatttgtatgtttcttcactgccaagatgtgttcaagcctgctatacctgccattgtattggaaggcttaatgaatttcatttattttctgcaacaacgattacagaatttattgcacaaaatgagacattttgagagtgatattaattacatgagggacaataggcatgaactaggattgttctaagcaaatcggaatcgggtcaccctgccacgttcaggtgcttggaccttcaggaaaagattgcccatcttgtcatttgaccaggcactgaagtgacaagaccatccttgagaagtcacatccaaagataaaattctgatccatttctagttttagtgtttcgccactgaagacttaacatatgtcttttacactcaggttgcaaaacacaggcccaagacaaacttaacttctcccccaaatcttccttccgctggtttttccatctcgtaagtggtgccactatccatctgttaaattgtttaggggaaacctagaaaagcactaccttaatcagtgttatccttcttcttaactgtgcgtcctaatttctccacatctttcttaagtgcagtgaccaaaccggatgagaattctaacacgggcctgacatcaaatggaaaggaaggataatgtccaggagttggaatgttatccttgtttttaattaagatgcaattcacataaattaactttttaagtgaacaattaagtggtagtacatccacaatggtgtacaaccaccacttctatctagctccaaaacattctcatcactccaaaagtaaagtcccgttactctccattttctcctcccaccgcccttgtccctggcaaccaccaatctgcttcctgtttctttggatttacatccgggtatttcatgtgagactcatacactgtgtattacttctttcgtctagctttaatgtgttgttgaggttgatccattgtaacatgttatcactacttcattcctttttatagctaagtatactttttatagtaagtatgccattgtagatatataccacaagtttatcgattcatccagttgagttgtttctactgtttggctaatgttcatagtgctgttatgaatgttcgtgtacaagtatttgagtccgtgttttcaattatttggggtatatgcctgggagtggagttgctgggtcatgttgaaatcgcacatttaactttttgaggaactgtcaaactttccctcagcagctgtaccgttttaccttccaccattgatgtatgagggttccaatttctccacaccttcaccaacacttattttgccattttaaaaattatagccatcctcatgggtgtggtctctcattgtggttttgatttgcatttccctgattactaatgatgtggagcatcttttgttgtctttggccatctgcgtatcttctttgaagaaatgtctgttgaggtcctttgttcattgaaattttgttgttgggttctgagttccttatatattctgggtactaggcccttataatattttcgcctataagtttttgctttataatgtcctcattgttttcaaacttactttatgtaatatgtacacttctaaaaaaaagaaacatggaaaagggcaaactgtaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:1385 -> Molecular function: GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] evidence: IDA
GeneID:1385 -> Molecular function: GO:0001102 [RNA polymerase II activating transcription factor binding] evidence: IPI
GeneID:1385 -> Molecular function: GO:0001190 [RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription] evidence: IDA
GeneID:1385 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:1385 -> Molecular function: GO:0003705 [RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:1385 -> Molecular function: GO:0003712 [transcription cofactor activity] evidence: TAS
GeneID:1385 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:1385 -> Molecular function: GO:0035497 [cAMP response element binding] evidence: IDA
GeneID:1385 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0006468 [protein phosphorylation] evidence: IDA
GeneID:1385 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
GeneID:1385 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0007202 [activation of phospholipase C activity] evidence: TAS
GeneID:1385 -> Biological process: GO:0007219 [Notch signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0007268 [synaptic transmission] evidence: TAS
GeneID:1385 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
GeneID:1385 -> Biological process: GO:0007595 [lactation] evidence: IEA
GeneID:1385 -> Biological process: GO:0008361 [regulation of cell size] evidence: IEA
GeneID:1385 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0010033 [response to organic substance] evidence: IDA
GeneID:1385 -> Biological process: GO:0010944 [negative regulation of transcription by competitive promoter binding] evidence: IDA
GeneID:1385 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
GeneID:1385 -> Biological process: GO:0021983 [pituitary gland development] evidence: IEA
GeneID:1385 -> Biological process: GO:0033363 [secretory granule organization] evidence: IEA
GeneID:1385 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0040018 [positive regulation of multicellular organism growth] evidence: IEA
GeneID:1385 -> Biological process: GO:0042493 [response to drug] evidence: IEA
GeneID:1385 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:1385 -> Biological process: GO:0045600 [positive regulation of fat cell differentiation] evidence: ISS
GeneID:1385 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: ISS
GeneID:1385 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:1385 -> Biological process: GO:0046887 [positive regulation of hormone secretion] evidence: IEA
GeneID:1385 -> Biological process: GO:0046889 [positive regulation of lipid biosynthetic process] evidence: ISS
GeneID:1385 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:1385 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: TAS
GeneID:1385 -> Biological process: GO:0050821 [protein stabilization] evidence: ISS
GeneID:1385 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: TAS
GeneID:1385 -> Biological process: GO:0060430 [lung saccule development] evidence: IEA
GeneID:1385 -> Biological process: GO:0060509 [Type I pneumocyte differentiation] evidence: IEA
GeneID:1385 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:1385 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:1385 -> Cellular component: GO:0005667 [transcription factor complex] evidence: IEA
GeneID:1385 -> Cellular component: GO:0005719 [nuclear euchromatin] evidence: IDA
GeneID:1385 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
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