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2025-05-09 18:32:22, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_014812 7204 bp mRNA linear PRI 09-JUN-2013
DEFINITION Homo sapiens centrosomal protein 170kDa (CEP170), transcript
variant alpha, mRNA.
ACCESSION NM_014812 XM_936267
VERSION NM_014812.2 GI:109255227
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7204)
AUTHORS Welburn,J.P. and Cheeseman,I.M.
TITLE The microtubule-binding protein Cep170 promotes the targeting of
the kinesin-13 depolymerase Kif2b to the mitotic spindle
JOURNAL Mol. Biol. Cell 23 (24), 4786-4795 (2012)
PUBMED 23087211
REMARK GeneRIF: Data indicate that Cep170 association with the C-terminus
of Kif2b enhances localization of Kif2b to the spindle.
REFERENCE 2 (bases 1 to 7204)
AUTHORS McCauley,J.L., Zuvich,R.L., Bradford,Y., Kenealy,S.J.,
Schnetz-Boutaud,N., Gregory,S.G., Hauser,S.L., Oksenberg,J.R.,
Mortlock,D.P., Pericak-Vance,M.A. and Haines,J.L.
TITLE Follow-up examination of linkage and association to chromosome 1q43
in multiple sclerosis
JOURNAL Genes Immun. 10 (7), 624-630 (2009)
PUBMED 19626040
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 7204)
AUTHORS Kim,J.E., Tannenbaum,S.R. and White,F.M.
TITLE Global phosphoproteome of HT-29 human colon adenocarcinoma cells
JOURNAL J. Proteome Res. 4 (4), 1339-1346 (2005)
PUBMED 16083285
REFERENCE 4 (bases 1 to 7204)
AUTHORS Guarguaglini,G., Duncan,P.I., Stierhof,Y.D., Holmstrom,T.,
Duensing,S. and Nigg,E.A.
TITLE The forkhead-associated domain protein Cep170 interacts with
Polo-like kinase 1 and serves as a marker for mature centrioles
JOURNAL Mol. Biol. Cell 16 (3), 1095-1107 (2005)
PUBMED 15616186
REMARK GeneRIF: Cep170 interacts with Polo-like kinase 1 in mature
centrioles.
REFERENCE 5 (bases 1 to 7204)
AUTHORS Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
TITLE Proteomic, functional, and domain-based analysis of in vivo 14-3-3
binding proteins involved in cytoskeletal regulation and cellular
organization
JOURNAL Curr. Biol. 14 (16), 1436-1450 (2004)
PUBMED 15324660
REFERENCE 6 (bases 1 to 7204)
AUTHORS Andersen,J.S., Wilkinson,C.J., Mayor,T., Mortensen,P., Nigg,E.A.
and Mann,M.
TITLE Proteomic characterization of the human centrosome by protein
correlation profiling
JOURNAL Nature 426 (6966), 570-574 (2003)
PUBMED 14654843
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP349680.1, BP349206.1,
AB022657.1, AC092782.2, AL606534.15 and CB410835.1.
This sequence is a reference standard in the RefSeqGene project.
On Jun 19, 2006 this sequence version replaced gi:7662141.
Summary: The product of this gene is a component of the centrosome,
a non-membraneous organelle that functions as the major
microtubule-organizing center in animal cells. During interphase,
the encoded protein localizes to the sub-distal appendages of
mature centrioles, which are microtubule-based structures thought
to help organize centrosomes. During mitosis, the protein
associates with spindle microtubules near the centrosomes. The
protein interacts with and is phosphorylated by polo-like kinase 1,
and functions in maintaining microtubule organization and cell
morphology. The human genome contains a putative transcribed
pseudogene. Several alternatively spliced transcript variants of
this gene have been found, but the full-length nature of some of
these variants has not been determined. [provided by RefSeq, Jul
2008].
Transcript Variant: This variant (alpha, also known as 1)
represents the longest transcript and encodes the longest isoform
(alpha).
##Evidence-Data-START##
CDS exon combination :: AB022657.1 [ECO:0000331]
RNAseq introns :: mixed/partial sample support ERS025081,
ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-274 BP349680.1 1-274
275-634 BP349206.1 222-581
635-1044 AB022657.1 280-689
1045-1045 AC092782.2 81447-81447 c
1046-5867 AB022657.1 691-5512
5868-6934 AL606534.15 138785-139851 c
6935-7204 CB410835.1 1-270
FEATURES Location/Qualifiers
source 1..7204
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q44"
gene 1..7204
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="centrosomal protein 170kDa"
/db_xref="GeneID:9859"
/db_xref="HGNC:28920"
/db_xref="MIM:613023"
exon 1..367
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 368..513
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
misc_feature 370..372
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="upstream in-frame stop codon"
CDS 409..5163
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="isoform alpha is encoded by transcript variant
alpha; XRCC5 binding protein; KARP-1-binding protein"
/codon_start=1
/product="centrosomal protein of 170 kDa isoform alpha"
/protein_id="NP_055627.2"
/db_xref="GI:109255228"
/db_xref="CCDS:CCDS44339.1"
/db_xref="GeneID:9859"
/db_xref="HGNC:28920"
/db_xref="MIM:613023"
/translation="
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
"
misc_feature 436..702
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="Forkhead associated domain (FHA); found in
eukaryotic and prokaryotic proteins. Putative nuclear
signalling domain. FHA domains may bind phosphothreonine,
phosphoserine and sometimes phosphotyrosine. In
eukaryotes, many FHA domain-containing proteins...;
Region: FHA; cd00060"
/db_xref="CDD:28942"
misc_feature <442..678
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="FOG: FHA domain [Signal transduction mechanisms];
Region: COG1716"
/db_xref="CDD:31902"
misc_feature order(487..489,520..522,526..531,595..603)
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="phosphopeptide binding site; other site"
/db_xref="CDD:28942"
misc_feature 1474..1476
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 1474..1476
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1483..1485
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 1483..1485
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1498..1500
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine; propagated from
UniProtKB/Swiss-Prot (Q5SW79.1); phosphorylation site"
misc_feature 1537..1539
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1744..1746
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 1897..1899
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 1909..1911
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q5SW79.1); phosphorylation site"
misc_feature 2287..2289
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2290..2292
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2296..2298
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2305..2307
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 2305..2307
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2314..2316
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 2314..2316
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2920..2922
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 2920..2922
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2965..5160
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5SW79.1);
Region: Targeting to microtubules"
misc_feature 3043..3045
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3190..3192
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3196..3198
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 3196..3198
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3205..3207
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 3205..3207
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3217..3219
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3280..3282
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 3319..3321
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3742..3744
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 3742..3744
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3745..5160
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q5SW79.1);
Region: Targeting to centrosomes"
misc_feature 3748..3750
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 3886..3888
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 3886..3888
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/citation=[3]
misc_feature 3901..3903
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 4159..4161
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 4186..4188
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4969..4971
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4972..4974
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
exon 514..603
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 604..682
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 683..741
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 742..904
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 905..1039
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1040..1516
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1517..1680
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1681..1974
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1975..2124
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
variation 2023
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:34312127"
exon 2125..2251
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 2252..4084
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
variation 2577
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="g"
/db_xref="dbSNP:2789194"
variation 2621
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="t"
/db_xref="dbSNP:3766664"
STS 3311..3443
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="G33981"
/db_xref="UniSTS:38719"
STS 3350..3525
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="D4S1286"
/db_xref="UniSTS:5571"
exon 4085..4319
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4320..4467
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4468..4638
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4639..4727
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4728..4821
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4822..4873
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4874..7184
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
variation 5119
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="g"
/replace="t"
/db_xref="dbSNP:11147"
variation 5127
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="t"
/db_xref="dbSNP:10881"
variation 5203
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:1046118"
variation 5279
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="g"
/db_xref="dbSNP:2787270"
variation 5326
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:2787271"
STS 5621..5780
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="G34957"
/db_xref="UniSTS:117667"
STS 5621..5780
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="RH67046"
/db_xref="UniSTS:90613"
variation 5868
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:1062985"
STS 6067..6979
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="KAB__6501"
/db_xref="UniSTS:464008"
variation 6172
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:2787273"
variation 6652
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:2789211"
STS 6947..7160
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="RH80002"
/db_xref="UniSTS:83593"
polyA_signal 7162..7167
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
polyA_site 7184
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
ORIGIN
gggcaagctggaaaagcgtgtgggtgagaccctcgcacaaccccttttcattgtctgtgtgtggcgcctgcgcagtaagggatcgttggaactgggcaggaggggatagggtccggctcctcgccctttcccgaggcgcctgcgcactaggcagtcggtctttgccgttaccgctatgtgtggggcgtgtgtggaataacgttattgcccagcggagctgagggccccggagctcgaccgcagcggcagcgacgacaacagcggcgacgacgacgacgacgaggtggggggaggacggcgtgcgagagactcacgggacgcgacgcgccccgcctcccccgtccggtccctctctccacggtaaggggatgacgtagctttgccaaagacttagaagctaagcagaaaatgagcttaacatcctggtttttggtgagcagtggaggcactcgccacaggctgccacgagaaatgatttttgttggaagagatgactgtgagctcatgttgcagtctcgtagtgtggataagcaacacgctgtcatcaactatgatgcgtctacggatgagcatttagtgaaggatttgggcagcctcaatgggacttttgtgaatgatgtaaggattccggaacagacttatatcaccttgaaacttgaagataagctgagatttggatatgatacaaatcttttcactgtagtacaaggagaaatgagggtccctgaagaagctcttaagcatgagaagtttaccattcagcttcagttgtcccaaaaatcttcagaatcagaattatccaaatctgcaagtgccaaaagcatagattcaaaggtagcagacgctgctactgaagtgcagcacaaaactactgaagcactgaaatccgaggaaaaagccatggatatttctgctatgccccgtggtactccattatatgggcagccgtcatggtggggggatgatgaggtggatgaaaaaagagctttcaagacaaatggcaaacctgaagaaaaaaaccatgaagctggaacatcagggtgcggcatagatgccaagcaagttgaggaacaatctgcagctgcaaatgaagaagtactttttcctttctgtagggaaccaagttattttgaaatccctacaaaagaattccagcaaccatcacaaataacagaaagcactattcatgaaatcccaacaaaagacacgccaagttcccatataacaggtgcagggcatgcttcatttaccattgaatttgatgacagtaccccagggaaggtaactattagagaccatgtgacaaagtttacttctgatcagcgccacaagtccaagaagtcttctcctggaactcaagacttgctggggattcaaacaggaatgatggcacccgaaaacaaagttgctgactggctagcacaaaacaaccctcctcaaatgctatgggaaagaacagaagaggattctaaaagcattaaaagtgatgttccagtgtacttgaaaaggttgaaaggaaataaacatgatgatggtacgcaaagtgattcagagaacgctggggctcacaggcgctgtagcaaacgtgcaactcttgaggaacacttaagacgccaccattcagaacacaaaaagctacagaaggtccaggctactgaaaagcatcaagaccaagctgttactagctctgcgcatcacagaggggggcatggtgttccacatgggaaattgttaaaacagaaatcagaggagccatcggtgtcaatacccttcctacaaactgcattattaagaagttcagggagtcttgggcacagaccaagccaggagatggataaaatgttaaaaaatcaagcaacttctgctacttctgaaaaggataatgatgatgaccaaagtgacaagggtacttataccattgagttagagaatcccaacagtgaggaagtggaagcaagaaaaatgattgacaaggtgtttggagtagatgacaatcaggattataataggcctgttatcaacgaaaaacataaagatctaataaaagattgggctctcagttctgctgcagcagtaatggaagaaagaaaaccactgactacatctggatttcaccactcagaggaaggcacatcttcatctggaagcaaacgttgggtttcacagtgggctagtttggctgccaatcatacaaggcatgatcaagaagaaaggataatggaattttctgcacctcttcctttagagaatgagacagagatcagtgagtctggcatgacagtgagaagtactggctctgcaacttccttggctagccagggagagagaaggagacgaactcttccccagcttccaaatgaagaaaagtctcttgagagccacagagcaaaggttgtaacacagaggtcagagataggagaaaaacaagacacagaacttcaggagaaagaaacacctacacaggtataccagaaagataaacaagatgctgacagacccttgagtaaaatgaacagggcagtaaatggagagactctcaaaactggtggagataataaaaccctacttcacttaggcagctctgctcctggaaaagagaaaagtgaaactgataaggaaacttctttggtaaagcaaacattagcaaaacttcaacaacaagaacaaagggaggaggctcagtggacacctactaaattgtcttccaaaaatgtttcaggtcagacagataaatgtagggaggaaacttttaaacaagaatcacaacctccagaaaaaaattcaggacattctacaagcaaaggagacagagtggcacaaagtgagagcaagagaagaaaagctgaggaaattctgaaaagtcagactccaaagggaggagacaagaaggaatcctccaagtcattagtgcgacaagggagcttcactatagaaaaacccagcccaaacatacccatagaacttattccccatataaataaacagacttcctctactccttcttctttagcattaacatctgcaagtagaatacgagaaagaagtgagtctttggatcctgattctagtatggacacaacccttattctaaaagacacagaagcagtaatggcttttctagaagctaaactacgtgaagataataaaactgatgaaggaccagatactcccagttataatagagacaattctatttcaccagaatctgatgtagatacagctagtacaatcagtctggttactggagaaactgaaagaaagtcaacccaaaagcgaaagagtttcactagcctctataaagataggtgttccacaggttctccttccaaagatgttacaaaatcatcatcttcaggtgctagggaaaaaatggaaaagaaaacaaaaagtcgttccacagatgtgggttcaagagcagatggtcgtaaatttgttcagtccagtgggagaataagacagccctcagtagacttaacagatgatgaccaaacctctagtgtacctcattctgccatctctgatattatgtcatctgatcaagaaacttactcttgtaaacctcatggacggactccacttacctcagctgatgagcatgtacattccaaactggaaggaagtaaagtaacgaaatctaagacttctccggtggtatctggttcatctagtaaatcaaccacccttccaaggccacgacctaccaggacttccctcttgcgcagagcacgacttggtgaagcttcagacagtgaacttgctgatgctgacaaagcatctgttgcttctgaagtatccacaacaagttctacatcaaaacctcccacaggaaggcgtaacatctctcggattgatttattggctcagcctcgtagaacacgacttggctcactgtcagctcgtagtgactctgaagcaacaatttctagaagtagtgcctcttcgaggaccgcagaagccatcattagaagtggagccagactagtaccatcagataaattttctcctagaattagagctaacagtatctctcgactctcagactccaaggtcaaaagtatgacctcagctcatggctctgcttcagtaaattcaagatggaggcgctttcctactgattatgcttccacctcagaagatgaatttggatcaaaccgtaattcccctaaacatacccgtctacgtacttctccagccctgaaaaccactcgcttgcagagcgctggatcagcaatgcctactagttcttcattcaaacaccggattaaagagcaggaagactacatccgagattggactgctcatcgagaagagatagccaggatcagccaagatcttgctctcattgctcgggagatcaacgatgtagcaggagagatagattcagtgacttcatcaggcactgcccctagtaccacagtaagcactgctgccaccacccctggctctgccatagacactagagaagagttggttgatcgtgtttttgatgaaagcctcaacttccgaaagattcctccattagttcattccaaaacaccagaaggaaacaacggtcgatctggtgatccaagacctcaagcagcagagcctcccgatcacttaacaattacaaggcggagaacctggagcagggatgaagtcatgggagataatctgctgctgtcatccgtctttcagttctctaagaagataagacaatctatagataagacagctggaaagatcagaatattatttaaagacaaagatcggaattgggatgacatagaaagcaaattaagagccgaaagtgaagtccctattgtgaaaacctcaagcatggagatttcttctatcttacaggaactgaaaagagtagaaaagcagctgcaagcaatcaatgctatgattgatcctgatggaactttggaggctctgaacaacatgggatttcccagtgctatgttgccatctccaccgaaacagaagtccagccctgtgaataaccaccacagcccgggtcagacaccaacacttggccaaccagaagctagggctcttcatcctgctgctgtttcagccgcagctgaatttgagaatgctgaatctgaggctgatttcagtatacatttcaatagattcaaccccgatggggaagaggaagatgttacagtacaagaatgactttctcttgattgttgaaaaatcattacctgtggaatggctaggaatattggaagcagcatagtgttgatgtacgcaaaacaagacagcttggtcagctacaatcttggaatccctgtcttcttaattttatttatttatttttgacgtataatgtagtatatcaatcctttcaaactatttagataaccacttgatgcacaaataggaaaaagcagattgtggcagtgtcgccttttgtggttttatgattttcaaattgaatttaatgattacaccctttcccttcatagatcttttttcttttttttaagccatgctgtgacctacaagcaaactaaatagccaacatttctgaacccctaagtctcctgtgccaagctgctccctgaaatggacttcttcatctgtacagatttgttaaaccattctatttgcttcttaataataggatttatattagtactcattaccattggacacaatgacataagtactctccacagtaaagcagacctttcacaacagtcactctgtgtcctaaaattttccaacatagatgtgatttatataactttgttgatacgtaaattgtcttggggtttacggaaattaactattatgtttgcactaagatttgctgggagtggtaggtggacatatctatatatcaataaggactaaccgtcttttttgtacataggagattgataatactgtatttgttttaagcccacagtgttttactccactttcaaaaagatcaatttggcactttttttcattttttttaatggaaataagatttggtctctcattttaggttaaatgataactagaaagattaaactagacagatagtttaggtggagtatatttttaaaactcagaacatgtatattggtcctgtgttaccaagtttatatgtgacagttgaaaaagaaattcccttgaaatgatcatgaggttaaaattttcttcattaggggacttggagaaccagtagtcgtaagattagttgatagtttcactcccaagcaatgaattgcttctgtgtgtttccctgtaggactcaatagtaaatgctgtctgtcttacacatttataaggaccctgcaagacgacgacaaaggcctttggcctgtgctactaaacaagaagcctatgaaaaatttcttctttaaacttgttttttctctttccagtaagttcacatttggataattttaaaaagaaaagtaattacctttgtgtttccagaacactataattggggtgtatcttaattcagttaaatattattagtagacctggattttcccccttgaccccatcagtctataaaggttaaactgcaacttttatgaaatggtctttaatatttccacaataatcctgtgctatatttgttttaagaaacaaagtaactctatacacttcaagactttacaggattttttaaatcctgtattgttggatcaattaataaagatgcaaaaaaactttatagagatgtaaaaacaaaactataatggatctcctatttttctttaaatacaaaaaaaaaaaggtaaatgaactattctccttgtaaagctaaattccccattctgtctaataaaggaagactgaaaaaaggttttaaagaacataaatggaaagatacaaatgctttgaaggaataaacgaaatgttaaaacagggtcaatccatttgaagaaaaagttggacaaaataatcagcattgctccctcttttatttaatatttgggtactgattatatccacatggaagtagaaggtaaggagtttaggaaaatactagaatctactctgcttacattcttgtttaagtgtttacacagtttggttcaattataaacatttggccttttactatgttatttttattttgtatgaatacattatcctccttatttatttttgttacatttattacttatgttattttgttatgcatttacaactccatttttaaataaagtgtttctggaactttaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9859 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:9859 -> Cellular component: GO:0005813 [centrosome] evidence: IDA
GeneID:9859 -> Cellular component: GO:0005814 [centriole] evidence: IEA
GeneID:9859 -> Cellular component: GO:0005819 [spindle] evidence: IEA
GeneID:9859 -> Cellular component: GO:0005874 [microtubule] evidence: IEA
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