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2025-05-09 18:30:42, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001042405 6832 bp mRNA linear PRI 09-JUN-2013
DEFINITION Homo sapiens centrosomal protein 170kDa (CEP170), transcript
variant gamma, mRNA.
ACCESSION NM_001042405 XM_001125768
VERSION NM_001042405.1 GI:109255231
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6832)
AUTHORS Welburn,J.P. and Cheeseman,I.M.
TITLE The microtubule-binding protein Cep170 promotes the targeting of
the kinesin-13 depolymerase Kif2b to the mitotic spindle
JOURNAL Mol. Biol. Cell 23 (24), 4786-4795 (2012)
PUBMED 23087211
REMARK GeneRIF: Data indicate that Cep170 association with the C-terminus
of Kif2b enhances localization of Kif2b to the spindle.
REFERENCE 2 (bases 1 to 6832)
AUTHORS McCauley,J.L., Zuvich,R.L., Bradford,Y., Kenealy,S.J.,
Schnetz-Boutaud,N., Gregory,S.G., Hauser,S.L., Oksenberg,J.R.,
Mortlock,D.P., Pericak-Vance,M.A. and Haines,J.L.
TITLE Follow-up examination of linkage and association to chromosome 1q43
in multiple sclerosis
JOURNAL Genes Immun. 10 (7), 624-630 (2009)
PUBMED 19626040
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 6832)
AUTHORS Kim,J.E., Tannenbaum,S.R. and White,F.M.
TITLE Global phosphoproteome of HT-29 human colon adenocarcinoma cells
JOURNAL J. Proteome Res. 4 (4), 1339-1346 (2005)
PUBMED 16083285
REFERENCE 4 (bases 1 to 6832)
AUTHORS Guarguaglini,G., Duncan,P.I., Stierhof,Y.D., Holmstrom,T.,
Duensing,S. and Nigg,E.A.
TITLE The forkhead-associated domain protein Cep170 interacts with
Polo-like kinase 1 and serves as a marker for mature centrioles
JOURNAL Mol. Biol. Cell 16 (3), 1095-1107 (2005)
PUBMED 15616186
REMARK GeneRIF: Cep170 interacts with Polo-like kinase 1 in mature
centrioles.
REFERENCE 5 (bases 1 to 6832)
AUTHORS Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
TITLE Proteomic, functional, and domain-based analysis of in vivo 14-3-3
binding proteins involved in cytoskeletal regulation and cellular
organization
JOURNAL Curr. Biol. 14 (16), 1436-1450 (2004)
PUBMED 15324660
REFERENCE 6 (bases 1 to 6832)
AUTHORS Andersen,J.S., Wilkinson,C.J., Mayor,T., Mortensen,P., Nigg,E.A.
and Mann,M.
TITLE Proteomic characterization of the human centrosome by protein
correlation profiling
JOURNAL Nature 426 (6966), 570-574 (2003)
PUBMED 14654843
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP349680.1, BP349206.1,
AB022659.1, AC092782.2 and CB410835.1.
On Sep 20, 2006 this sequence version replaced gi:113412733.
Summary: The product of this gene is a component of the centrosome,
a non-membraneous organelle that functions as the major
microtubule-organizing center in animal cells. During interphase,
the encoded protein localizes to the sub-distal appendages of
mature centrioles, which are microtubule-based structures thought
to help organize centrosomes. During mitosis, the protein
associates with spindle microtubules near the centrosomes. The
protein interacts with and is phosphorylated by polo-like kinase 1,
and functions in maintaining microtubule organization and cell
morphology. The human genome contains a putative transcribed
pseudogene. Several alternatively spliced transcript variants of
this gene have been found, but the full-length nature of some of
these variants has not been determined. [provided by RefSeq, Jul
2008].
Transcript Variant: This variant (gamma, also known as 3) has
multiple differences in the coding region but maintains the reading
frame, compared to variant alpha, resulting in a shorter protein
(isoform gamma), compared to isoform alpha.
##Evidence-Data-START##
CDS exon combination :: BC146790.1, AB007939.1 [ECO:0000331]
RNAseq introns :: mixed/partial sample support ERS025081,
ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-274 BP349680.1 1-274
275-634 BP349206.1 222-581
635-1044 AB022659.1 280-689
1045-1045 AC092782.2 81447-81447 c
1046-6562 AB022659.1 691-6207
6563-6832 CB410835.1 1-270
FEATURES Location/Qualifiers
source 1..6832
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q44"
gene 1..6832
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="centrosomal protein 170kDa"
/db_xref="GeneID:9859"
/db_xref="HGNC:28920"
/db_xref="MIM:613023"
exon 1..367
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 368..513
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
misc_feature 370..372
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="upstream in-frame stop codon"
CDS 409..4791
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="isoform gamma is encoded by transcript variant
gamma; XRCC5 binding protein; KARP-1-binding protein"
/codon_start=1
/product="centrosomal protein of 170 kDa isoform gamma"
/protein_id="NP_001035864.1"
/db_xref="GI:109255232"
/db_xref="CCDS:CCDS44338.1"
/db_xref="GeneID:9859"
/db_xref="HGNC:28920"
/db_xref="MIM:613023"
/translation="
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
"
misc_feature 436..702
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="Forkhead associated domain (FHA); found in
eukaryotic and prokaryotic proteins. Putative nuclear
signalling domain. FHA domains may bind phosphothreonine,
phosphoserine and sometimes phosphotyrosine. In
eukaryotes, many FHA domain-containing proteins...;
Region: FHA; cd00060"
/db_xref="CDD:28942"
misc_feature <442..678
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="FOG: FHA domain [Signal transduction mechanisms];
Region: COG1716"
/db_xref="CDD:31902"
misc_feature order(487..489,520..522,526..531,595..603)
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/note="phosphopeptide binding site; other site"
/db_xref="CDD:28942"
misc_feature 1474..1476
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 1474..1476
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1483..1485
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q5SW79.1); phosphorylation site"
misc_feature 1483..1485
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1498..1500
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine; propagated from
UniProtKB/Swiss-Prot (Q5SW79.1); phosphorylation site"
misc_feature 1537..1539
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1993..1995
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1996..1998
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2002..2004
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2011..2013
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2020..2022
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2626..2628
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2749..2751
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2896..2898
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2902..2904
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2911..2913
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2923..2925
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3025..3027
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 3448..3450
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4597..4599
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 4600..4602
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
exon 514..603
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 604..682
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 683..741
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 742..904
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 905..1039
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1040..1516
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1517..1680
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1681..1830
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
variation 1729
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:34312127"
exon 1831..1957
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 1958..3790
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
variation 2283
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="g"
/db_xref="dbSNP:2789194"
variation 2327
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="t"
/db_xref="dbSNP:3766664"
STS 3017..3149
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="G33981"
/db_xref="UniSTS:38719"
STS 3056..3231
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="D4S1286"
/db_xref="UniSTS:5571"
exon 3791..3917
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 3918..4095
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4096..4266
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4267..4355
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4356..4449
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4450..4501
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
exon 4502..6812
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/inference="alignment:Splign:1.39.8"
variation 4747
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="g"
/replace="t"
/db_xref="dbSNP:11147"
variation 4755
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="t"
/db_xref="dbSNP:10881"
variation 4831
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:1046118"
variation 4907
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="c"
/replace="g"
/db_xref="dbSNP:2787270"
variation 4954
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:2787271"
STS 5249..5408
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="G34957"
/db_xref="UniSTS:117667"
STS 5249..5408
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="RH67046"
/db_xref="UniSTS:90613"
variation 5496
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:1062985"
STS 5695..6607
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="KAB__6501"
/db_xref="UniSTS:464008"
variation 5800
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:2787273"
variation 6280
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/replace="a"
/replace="g"
/db_xref="dbSNP:2789211"
STS 6575..6788
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
/standard_name="RH80002"
/db_xref="UniSTS:83593"
polyA_signal 6790..6795
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
polyA_site 6812
/gene="CEP170"
/gene_synonym="FAM68A; KAB; KIAA0470"
ORIGIN
gggcaagctggaaaagcgtgtgggtgagaccctcgcacaaccccttttcattgtctgtgtgtggcgcctgcgcagtaagggatcgttggaactgggcaggaggggatagggtccggctcctcgccctttcccgaggcgcctgcgcactaggcagtcggtctttgccgttaccgctatgtgtggggcgtgtgtggaataacgttattgcccagcggagctgagggccccggagctcgaccgcagcggcagcgacgacaacagcggcgacgacgacgacgacgaggtggggggaggacggcgtgcgagagactcacgggacgcgacgcgccccgcctcccccgtccggtccctctctccacggtaaggggatgacgtagctttgccaaagacttagaagctaagcagaaaatgagcttaacatcctggtttttggtgagcagtggaggcactcgccacaggctgccacgagaaatgatttttgttggaagagatgactgtgagctcatgttgcagtctcgtagtgtggataagcaacacgctgtcatcaactatgatgcgtctacggatgagcatttagtgaaggatttgggcagcctcaatgggacttttgtgaatgatgtaaggattccggaacagacttatatcaccttgaaacttgaagataagctgagatttggatatgatacaaatcttttcactgtagtacaaggagaaatgagggtccctgaagaagctcttaagcatgagaagtttaccattcagcttcagttgtcccaaaaatcttcagaatcagaattatccaaatctgcaagtgccaaaagcatagattcaaaggtagcagacgctgctactgaagtgcagcacaaaactactgaagcactgaaatccgaggaaaaagccatggatatttctgctatgccccgtggtactccattatatgggcagccgtcatggtggggggatgatgaggtggatgaaaaaagagctttcaagacaaatggcaaacctgaagaaaaaaaccatgaagctggaacatcagggtgcggcatagatgccaagcaagttgaggaacaatctgcagctgcaaatgaagaagtactttttcctttctgtagggaaccaagttattttgaaatccctacaaaagaattccagcaaccatcacaaataacagaaagcactattcatgaaatcccaacaaaagacacgccaagttcccatataacaggtgcagggcatgcttcatttaccattgaatttgatgacagtaccccagggaaggtaactattagagaccatgtgacaaagtttacttctgatcagcgccacaagtccaagaagtcttctcctggaactcaagacttgctggggattcaaacaggaatgatggcacccgaaaacaaagttgctgactggctagcacaaaacaaccctcctcaaatgctatgggaaagaacagaagaggattctaaaagcattaaaagtgatgttccagtgtacttgaaaaggttgaaaggaaataaacatgatgatggtacgcaaagtgattcagagaacgctggggctcacaggcgctgtagcaaacgtgcaactcttgaggaacacttaagacgccaccattcagaacacaaaaagctacagaaggtccaggctactgaaaagcatcaagaccaagctgttgtgtttggagtagatgacaatcaggattataataggcctgttatcaacgaaaaacataaagatctaataaaagattgggctctcagttctgctgcagcagtaatggaagaaagaaaaccactgactacatctggatttcaccactcagaggaaggcacatcttcatctggaagcaaacgttgggtttcacagtgggctagtttggctgccaatcatacaaggcatgatcaagaagaaaggataatggaattttctgcacctcttcctttagagaatgagacagagatcagtgagtctggcatgacagtgagaagtactggctctgcaacttccttggctagccagggagagagaaggagacgaactcttccccagcttccaaatgaagaaaagtctcttgagagccacagagcaaaggttgtaacacagaggtcagagataggagaaaaacaagacacagaacttcaggagaaagaaacacctacacaggtataccagaaagataaacaagatgctgacagacccttgagtaaaatgaacagggcagtaaatggagagactctcaaaactggtggagataataaaaccctacttcacttaggcagctctgctcctggaaaagagaaaagtgaaactgataaggaaacttctttggtaaagcaaacattagcaaaacttcaacaacaagaacaaagggaggaggctcagtggacacctactaaattgtcttccaaaaatgtttcaggtcagacagataaatgtagggaggaaacttttaaacaagaatcacaacctccagaaaaaaattcaggacattctacaagcaaaggagacagagtggcacaaagtgagagcaagagaagaaaagctgaggaaattctgaaaagtcagactccaaagggaggagacaagaaggaatcctccaagtcattagtgcgacaagggagcttcactatagaaaaacccagcccaaacatacccatagaacttattccccatataaataaacagacttcctctactccttcttctttagcattaacatctgcaagtagaatacgagaaagaagtgagtctttggatcctgattctagtatggacacaacccttattctaaaagacacagaagcagtaatggcttttctagaagctaaactacgtgaagataataaaactgatgaaggaccagatactcccagttataatagagacaattctatttcaccagaatctgatgtagatacagctagtacaatcagtctggttactggagaaactgaaagaaagtcaacccaaaagcgaaagagtttcactagcctctataaagataggtgttccacaggttctccttccaaagatgttacaaaatcatcatcttcaggtgctagggaaaaaatggaaaagaaaacaaaaagtcgttccacagatgtgggttcaagagcagatggtcgtaaatttgttcagtccagtgggagaataagacagccctcagtagacttaacagatgatgaccaaacctctagtgtacctcattctgccatctctgatattatgtcatctgatcaagaaacttactcttgtaaacctcatggacggactccacttacctcagctgatgagcatgtacattccaaactggaaggaagtaaagtaacgaaatctaagacttctccggtggtatctggttcatctagtaaatcaaccacccttccaaggccacgacctaccaggacttccctcttgcgcagagcacgacttggtgaagcttcagacagtgaacttgctgatgctgacaaagcatctgttgcttctgaagtatccacaacaagttctacatcaaaacctcccacaggaaggcgtaacatctctcggattgatttattggctcagcctcgtagaacacgacttggctcactgtcagctcgtagtgactctgaagcaacaatttctagaagtagtgcctcttcgaggaccgcagaagccatcattagaagtggagccagactagtaccatcagataaattttctcctagaattagagctaacagtatctctcgactctcagactccaaggtcaaaagtatgacctcagctcatggctctgcttcagccctgaaaaccactcgcttgcagagcgctggatcagcaatgcctactagttcttcattcaaacaccggattaaagagcaggaagactacatccgagattggactgctcatcgagaagagatagccaggatcagccaagatcttgctctcattgctcgggagatcaacgatgtagcaggagagatagattcagtgacttcatcaggcactgcccctagtaccacagtaagcactgctgccaccacccctggctctgccatagacactagagaagaggtaggagatcttcatggagaaatgcataagttggttgatcgtgtttttgatgaaagcctcaacttccgaaagattcctccattagttcattccaaaacaccagaaggaaacaacggtcgatctggtgatccaagacctcaagcagcagagcctcccgatcacttaacaattacaaggcggagaacctggagcagggatgaagtcatgggagataatctgctgctgtcatccgtctttcagttctctaagaagataagacaatctatagataagacagctggaaagatcagaatattatttaaagacaaagatcggaattgggatgacatagaaagcaaattaagagccgaaagtgaagtccctattgtgaaaacctcaagcatggagatttcttctatcttacaggaactgaaaagagtagaaaagcagctgcaagcaatcaatgctatgattgatcctgatggaactttggaggctctgaacaacatgggatttcccagtgctatgttgccatctccaccgaaacagaagtccagccctgtgaataaccaccacagcccgggtcagacaccaacacttggccaaccagaagctagggctcttcatcctgctgctgtttcagccgcagctgaatttgagaatgctgaatctgaggctgatttcagtatacatttcaatagattcaaccccgatggggaagaggaagatgttacagtacaagaatgactttctcttgattgttgaaaaatcattacctgtggaatggctaggaatattggaagcagcatagtgttgatgtacgcaaaacaagacagcttggtcagctacaatcttggaatccctgtcttcttaattttatttatttatttttgacgtataatgtagtatatcaatcctttcaaactatttagataaccacttgatgcacaaataggaaaaagcagattgtggcagtgtcgccttttgtggttttatgattttcaaattgaatttaatgattacaccctttcccttcatagatcttttttcttttttttaagccatgctgtgacctacaagcaaactaaatagccaacatttctgaacccctaagtctcctgtgccaagctgctccctgaaatggacttcttcatctgtacagatttgttaaaccattctatttgcttcttaataataggatttatattagtactcattaccattggacacaatgacataagtactctccacagtaaagcagacctttcacaacagtcactctgtgtcctaaaattttccaacatagatgtgatttatataactttgttgatacgtaaattgtcttggggtttacggaaattaactattatgtttgcactaagatttgctgggagtggtaggtggacatatctatatatcaataaggactaaccgtcttttttgtacataggagattgataatactgtatttgttttaagcccacagtgttttactccactttcaaaaagatcaatttggcactttttttcattttttttaatggaaataagatttggtctctcattttaggttaaatgataactagaaagattaaactagacagatagtttaggtggagtatatttttaaaactcagaacatgtatattggtcctgtgttaccaagtttatatgtgacagttgaaaaagaaattcccttgaaatgatcatgaggttaaaattttcttcattaggggacttggagaaccagtagtcgtaagattagttgatagtttcactcccaagcaatgaattgcttctgtgtgtttccctgtaggactcaatagtaaatgctgtctgtcttacacatttataaggaccctgcaagacgacgacaaaggcctttggcctgtgctactaaacaagaagcctatgaaaaatttcttctttaaacttgttttttctctttccagtaagttcacatttggataattttaaaaagaaaagtaattacctttgtgtttccagaacactataattggggtgtatcttaattcagttaaatattattagtagacctggattttcccccttgaccccatcagtctataaaggttaaactgcaacttttatgaaatggtctttaatatttccacaataatcctgtgctatatttgttttaagaaacaaagtaactctatacacttcaagactttacaggattttttaaatcctgtattgttggatcaattaataaagatgcaaaaaaactttatagagatgtaaaaacaaaactataatggatctcctatttttctttaaatacaaaaaaaaaaaggtaaatgaactattctccttgtaaagctaaattccccattctgtctaataaaggaagactgaaaaaaggttttaaagaacataaatggaaagatacaaatgctttgaaggaataaacgaaatgttaaaacagggtcaatccatttgaagaaaaagttggacaaaataatcagcattgctccctcttttatttaatatttgggtactgattatatccacatggaagtagaaggtaaggagtttaggaaaatactagaatctactctgcttacattcttgtttaagtgtttacacagtttggttcaattataaacatttggccttttactatgttatttttattttgtatgaatacattatcctccttatttatttttgttacatttattacttatgttattttgttatgcatttacaactccatttttaaataaagtgtttctggaactttaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9859 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:9859 -> Cellular component: GO:0005813 [centrosome] evidence: IDA
GeneID:9859 -> Cellular component: GO:0005814 [centriole] evidence: IEA
GeneID:9859 -> Cellular component: GO:0005819 [spindle] evidence: IEA
GeneID:9859 -> Cellular component: GO:0005874 [microtubule] evidence: IEA
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