LOCUS       NM_003945                894 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
            (ATP6V0E1), mRNA.
ACCESSION   NM_003945
VERSION     NM_003945.3  GI:50593534
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 894)
  AUTHORS   Lu,M., Ammar,D., Ives,H., Albrecht,F. and Gluck,S.L.
  TITLE     Physical interaction between aldolase and vacuolar H+-ATPase is
            essential for the assembly and activity of the proton pump
  JOURNAL   J. Biol. Chem. 282 (34), 24495-24503 (2007)
   PUBMED   17576770
  REMARK    GeneRIF: there is an important role for physical association
            between aldolase and the A, B and E subunits of V-ATPase in the
            regulation of the proton pump
REFERENCE   2  (bases 1 to 894)
  AUTHORS   Adachi,K., Oiwa,K., Nishizaka,T., Furuike,S., Noji,H., Itoh,H.,
            Yoshida,M. and Kinosita,K. Jr.
  TITLE     Coupling of rotation and catalysis in F(1)-ATPase revealed by
            single-molecule imaging and manipulation
  JOURNAL   Cell 130 (2), 309-321 (2007)
   PUBMED   17662945
REFERENCE   3  (bases 1 to 894)
  AUTHORS   Blake-Palmer,K.G., Su,Y., Smith,A.N. and Karet,F.E.
  TITLE     Molecular cloning and characterization of a novel form of the human
            vacuolar H+-ATPase e-subunit: an essential proton pump component
  JOURNAL   Gene 393 (1-2), 94-100 (2007)
   PUBMED   17350184
REFERENCE   4  (bases 1 to 894)
  AUTHORS   Wang,H.L., Zhu,Z.M., Yerle,M., Wu,X., Wang,H., Yang,S.L. and Li,K.
  TITLE     Full-length coding sequences and mapping of porcine ATP6VOE and
            ATP5G1 genes
  JOURNAL   Cytogenet. Genome Res. 109 (4), 533 (2005)
   PUBMED   15906478
REFERENCE   5  (bases 1 to 894)
  AUTHORS   Sambade,M. and Kane,P.M.
  TITLE     The yeast vacuolar proton-translocating ATPase contains a subunit
            homologous to the Manduca sexta and bovine e subunits that is
            essential for function
  JOURNAL   J. Biol. Chem. 279 (17), 17361-17365 (2004)
   PUBMED   14970230
REFERENCE   6  (bases 1 to 894)
  AUTHORS   Nelson,N. and Harvey,W.R.
  TITLE     Vacuolar and plasma membrane proton-adenosinetriphosphatases
  JOURNAL   Physiol. Rev. 79 (2), 361-385 (1999)
   PUBMED   10221984
  REMARK    Review article
REFERENCE   7  (bases 1 to 894)
  AUTHORS   Ludwig,J., Kerscher,S., Brandt,U., Pfeiffer,K., Getlawi,F.,
            Apps,D.K. and Schagger,H.
  TITLE     Identification and characterization of a novel 9.2-kDa membrane
            sector-associated protein of vacuolar proton-ATPase from chromaffin
            granules
  JOURNAL   J. Biol. Chem. 273 (18), 10939-10947 (1998)
   PUBMED   9556572
REFERENCE   8  (bases 1 to 894)
  AUTHORS   Finbow,M.E. and Harrison,M.A.
  TITLE     The vacuolar H+-ATPase: a universal proton pump of eukaryotes
  JOURNAL   Biochem. J. 324 (PT 3), 697-712 (1997)
   PUBMED   9210392
  REMARK    Review article
REFERENCE   9  (bases 1 to 894)
  AUTHORS   Stevens,T.H. and Forgac,M.
  TITLE     Structure, function and regulation of the vacuolar (H+)-ATPase
  JOURNAL   Annu. Rev. Cell Dev. Biol. 13, 779-808 (1997)
   PUBMED   9442887
  REMARK    Review article
REFERENCE   10 (bases 1 to 894)
  AUTHORS   Dautry-Varsat,A.
  TITLE     Receptor-mediated endocytosis: the intracellular journey of
            transferrin and its receptor
  JOURNAL   Biochimie 68 (3), 375-381 (1986)
   PUBMED   2874839
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BF691381.1, Y15286.1 and
            AI198465.1.
            On Jul 26, 2004 this sequence version replaced gi:19913435.
            
            Summary: This gene encodes a component of vacuolar ATPase
            (V-ATPase), a multisubunit enzyme that mediates acidification of
            eukaryotic intracellular organelles. V-ATPase dependent organelle
            acidification is necessary for such intracellular processes as
            protein sorting, zymogen activation, receptor-mediated endocytosis,
            and synaptic vesicle proton gradient generation. V-ATPase is
            composed of a cytosolic V1 domain and a transmembrane V0 domain.
            The V1 domain consists of three A and three B subunits, two G
            subunits plus the C, D, E, F, and H subunits. The V1 domain
            contains the ATP catalytic site. The V0 domain consists of five
            different subunits: a, c, c', c', and d. Additional isoforms of
            many of the V1 and V0 subunit proteins are encoded by multiple
            genes or alternatively spliced transcript variants. This encoded
            protein is possibly part of the V0 subunit. Since two
            nontranscribed pseudogenes have been found in dog, it is possible
            that the localization to chromosome 2 for this gene by radiation
            hybrid mapping is representing a pseudogene. Genomic mapping puts
            the chromosomal location on 5q35.3. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BI763465.1, BG623204.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                BF691381.1         1-39
            40-875              Y15286.1           1-836
            876-894             AI198465.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q35.1"
     gene            1..894
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /note="ATPase, H+ transporting, lysosomal 9kDa, V0 subunit
                     e1"
                     /db_xref="GeneID:8992"
                     /db_xref="HGNC:863"
                     /db_xref="HPRD:04894"
                     /db_xref="MIM:603931"
     exon            1..205
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /inference="alignment:Splign:1.39.8"
     variation       26
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2302956"
     misc_feature    63..65
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /note="upstream in-frame stop codon"
     variation       69
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201017640"
     variation       77
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200271343"
     variation       79
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:580437"
     variation       81
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374943687"
     CDS             102..347
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /EC_number="3.6.3.14"
                     /note="vacuolar ATP synthase subunit H; V-ATPase H
                     subunit; vacuolar proton pump H subunit; V-ATPase M9.2
                     subunit; V-ATPase 9.2 kDa membrane accessory protein;
                     H(+)-transporting two-sector ATPase, subunit H; vacuolar
                     proton-ATPase subunit M9.2; V-ATPase subunit e 1; vacuolar
                     proton pump subunit e 1"
                     /codon_start=1
                     /product="V-type proton ATPase subunit e 1"
                     /protein_id="NP_003936.1"
                     /db_xref="GI:4502319"
                     /db_xref="CCDS:CCDS4383.1"
                     /db_xref="GeneID:8992"
                     /db_xref="HGNC:863"
                     /db_xref="HPRD:04894"
                     /db_xref="MIM:603931"
                     /translation="

MAYHGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP

"
     misc_feature    123..317
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /note="ATP synthase subunit H; Region: ATP_synt_H;
                     pfam05493"
                     /db_xref="CDD:147590"
     misc_feature    123..185
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O15342.2);
                     transmembrane region"
     misc_feature    207..269
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (O15342.2);
                     transmembrane region"
     variation       125
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35000513"
     variation       156
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370754384"
     variation       159
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199759060"
     variation       161
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367681823"
     variation       171
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201460422"
     variation       195
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370904068"
     exon            206..253
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /inference="alignment:Splign:1.39.8"
     variation       247
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372332112"
     variation       249
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:207466625"
     exon            254..383
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /inference="alignment:Splign:1.39.8"
     variation       267
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151242113"
     variation       284
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140462911"
     variation       312
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11539177"
     variation       334
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147105290"
     variation       349
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111415356"
     variation       354
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78825938"
     variation       373
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367719776"
     variation       376
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370117916"
     exon            384..882
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /inference="alignment:Splign:1.39.8"
     variation       425
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11539179"
     variation       481
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11539180"
     variation       501
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11539178"
     STS             509..684
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /standard_name="G61995"
                     /db_xref="UniSTS:139214"
     variation       554
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146948215"
     variation       555
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73806203"
     variation       593
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:13017"
     variation       597
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11934"
     variation       613
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189654022"
     STS             618..800
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /standard_name="STS-H56007"
                     /db_xref="UniSTS:49353"
     variation       641
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138021157"
     variation       680
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142120765"
     variation       740
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1062990"
     variation       745
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1062989"
     variation       746
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:114419174"
     variation       759
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11539172"
     variation       788..789
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11539166"
     variation       799
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:15179"
     variation       801
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:150151566"
     variation       817..818
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11539171"
     variation       817
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:15182"
     variation       823
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11539173"
     variation       834
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:15180"
     variation       847
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181211141"
     polyA_signal    849..854
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
     variation       866
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4849"
     variation       873
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1139927"
     variation       875
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:60728179"
     polyA_site      882
                     /gene="ATP6V0E1"
                     /gene_synonym="ATP6H; ATP6V0E; M9.2; Vma21; Vma21p"
                     /experiment="experimental evidence, no additional details
                     recorded"
ORIGIN      

aggcggggcttgcacacgctggtcacgcggtcagctattgacacttcctggtgggatccgagtgaggcgacggggtaggggttggcgctcaggcggcgaccatggcgtatcacggcctcactgtgcctctcattgtgatgagcgtgttctggggcttcgtcggcttcttggtgccttggttcatccctaagggtcctaaccggggagttatcattaccatgttggtgacctgttcagtttgctgctatctcttttggctgattgcaattctggcccaactcaaccctctctttggaccgcaattgaaaaatgaaaccatctggtatctgaagtatcattggccttgaggaagaagacatgctctacagtgctcagtctttgaggtcacgagaagagaatgccttctagatgcaaaatcacctccaaaccagaccacttttcttgacttgcctgttttggccattagctgccttaaacgttaacagcacatttgaatgccttattctacaatgcagcgtgttttcctttgccttttttgcactttggtgaattacgtgcctccataacctgaactgtgccgactccacaaaacgattatgtactcttctgagatagaagatgctgttcttctgagagatacgttactctctccttggaatctgtggatttgaagatggctcctgccttctcacgtgggaatcagtgaagtgtttagaaactgctgcaagacaaacaagactccagtggggtggtcagtaggagagcacgttcagagggaagagccatctcaacagaatcgcaccaaactatactttcaggatgaatttcttctttctgccatcttttggaataaatattttcctcctttctatggaaatctggaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:8992 -> Molecular function: GO:0005215 [transporter activity] evidence: NAS
            GeneID:8992 -> Molecular function: GO:0042625 [ATPase activity, coupled to transmembrane movement of ions] evidence: ISS
            GeneID:8992 -> Molecular function: GO:0046961 [proton-transporting ATPase activity, rotational mechanism] evidence: TAS
            GeneID:8992 -> Biological process: GO:0006879 [cellular iron ion homeostasis] evidence: TAS
            GeneID:8992 -> Biological process: GO:0007035 [vacuolar acidification] evidence: ISS
            GeneID:8992 -> Biological process: GO:0008286 [insulin receptor signaling pathway] evidence: TAS
            GeneID:8992 -> Biological process: GO:0015991 [ATP hydrolysis coupled proton transport] evidence: IEA
            GeneID:8992 -> Biological process: GO:0015992 [proton transport] evidence: TAS
            GeneID:8992 -> Biological process: GO:0016049 [cell growth] evidence: IGI
            GeneID:8992 -> Biological process: GO:0033572 [transferrin transport] evidence: TAS
            GeneID:8992 -> Biological process: GO:0043200 [response to amino acid stimulus] evidence: IEA
            GeneID:8992 -> Biological process: GO:0051701 [interaction with host] evidence: TAS
            GeneID:8992 -> Biological process: GO:0055085 [transmembrane transport] evidence: TAS
            GeneID:8992 -> Biological process: GO:0090382 [phagosome maturation] evidence: TAS
            GeneID:8992 -> Cellular component: GO:0010008 [endosome membrane] evidence: TAS
            GeneID:8992 -> Cellular component: GO:0016020 [membrane] evidence: TAS
            GeneID:8992 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
            GeneID:8992 -> Cellular component: GO:0030670 [phagocytic vesicle membrane] evidence: TAS
            GeneID:8992 -> Cellular component: GO:0033179 [proton-transporting V-type ATPase, V0 domain] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_003936 -> EC 3.6.3.14