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2025-05-09 18:35:44, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_014646 6245 bp mRNA linear PRI 10-JUL-2013
DEFINITION Homo sapiens lipin 2 (LPIN2), mRNA.
ACCESSION NM_014646
VERSION NM_014646.2 GI:22027649
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6245)
AUTHORS Herlin T, Fiirgaard B, Bjerre M, Kerndrup G, Hasle H, Bing X and
Ferguson PJ.
TITLE Efficacy of anti-IL-1 treatment in Majeed syndrome
JOURNAL Ann. Rheum. Dis. 72 (3), 410-413 (2013)
PUBMED 23087183
REMARK GeneRIF: We describe two brothers with Majeed syndrome, homozygous
novel 2-base pair deletion in LPIN2 (c.1312_1313delCT;
p.Leu438fs+16X)
REFERENCE 2 (bases 1 to 6245)
AUTHORS Michot C, Hubert L, Romero NB, Gouda A, Mamoune A, Mathew S, Kirk
E, Viollet L, Rahman S, Bekri S, Peters H, McGill J, Glamuzina E,
Farrar M, von der Hagen M, Alexander IE, Kirmse B, Barth M, Laforet
P, Benlian P, Munnich A, JeanPierre M, Elpeleg O, Pines O,
Delahodde A, de Keyzer Y and de Lonlay P.
TITLE Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and
exercise-induced myalgia
JOURNAL J. Inherit. Metab. Dis. 35 (6), 1119-1128 (2012)
PUBMED 22481384
REMARK GeneRIF: LPIN1-related myolysis constitutes a major cause of
early-onset rhabdomyolysis and occasionally in adults. Heterozygous
LPIN1 mutations may cause mild muscular symptoms. No major defects
of LPIN2 or LPIN3 genes were associated with muscle manifestations.
REFERENCE 3 (bases 1 to 6245)
AUTHORS Valdearcos M, Esquinas E, Meana C, Pena L, Gil-de-Gomez L, Balsinde
J and Balboa MA.
TITLE Lipin-2 reduces proinflammatory signaling induced by saturated
fatty acids in macrophages
JOURNAL J. Biol. Chem. 287 (14), 10894-10904 (2012)
PUBMED 22334674
REMARK GeneRIF: role of lipin-2 in the proinflammatory action of saturated
fatty acids in murine and human macrophages
REFERENCE 4 (bases 1 to 6245)
AUTHORS Sim X, Ong RT, Suo C, Tay WT, Liu J, Ng DP, Boehnke M, Chia KS,
Wong TY, Seielstad M, Teo YY and Tai ES.
TITLE Transferability of type 2 diabetes implicated loci in multi-ethnic
cohorts from Southeast Asia
JOURNAL PLoS Genet. 7 (4), E1001363 (2011)
PUBMED 21490949
REFERENCE 5 (bases 1 to 6245)
AUTHORS Liu GH, Qu J, Carmack AE, Kim HB, Chen C, Ren H, Morris AJ, Finck
BN and Harris TE.
TITLE Lipin proteins form homo- and hetero-oligomers
JOURNAL Biochem. J. 432 (1), 65-76 (2010)
PUBMED 20735359
REMARK GeneRIF: Data revealed that lipin 1 formed stable homo-oligomers
with itself and hetero-oligomers with lipin 2/3.
REFERENCE 6 (bases 1 to 6245)
AUTHORS Aulchenko YS, Pullen J, Kloosterman WP, Yazdanpanah M, Hofman A,
Vaessen N, Snijders PJ, Zubakov D, Mackay I, Olavesen M, Sidhu B,
Smith VE, Carey A, Berezikov E, Uitterlinden AG, Plasterk RH,
Oostra BA and van Duijn CM.
TITLE LPIN2 is associated with type 2 diabetes, glucose metabolism, and
body composition
JOURNAL Diabetes 56 (12), 3020-3026 (2007)
PUBMED 17804763
REMARK GeneRIF: A single nucleotide polymorphism of the LPIN2 gene is
associated with type 2 diabetes and fat distribution.
GeneRIF: Observational study of gene-disease association and
gene-environment interaction. (HuGE Navigator)
REFERENCE 7 (bases 1 to 6245)
AUTHORS Ferguson PJ, Chen S, Tayeh MK, Ochoa L, Leal SM, Pelet A, Munnich
A, Lyonnet S, Majeed HA and El-Shanti H.
TITLE Homozygous mutations in LPIN2 are responsible for the syndrome of
chronic recurrent multifocal osteomyelitis and congenital
dyserythropoietic anaemia (Majeed syndrome)
JOURNAL J. Med. Genet. 42 (7), 551-557 (2005)
PUBMED 15994876
REMARK GeneRIF: We conclude that homozygous mutations in LPIN2 result in
Majeed syndrome. Understanding the aberrant immune response in this
condition will shed light on the aetiology of other inflammatory
disorders of multifactorial aetiology
REFERENCE 8 (bases 1 to 6245)
AUTHORS Zhou J and Young TL.
TITLE Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1
high-grade myopia
JOURNAL Gene 352, 10-19 (2005)
PUBMED 15862761
REMARK GeneRIF: LPIN2 gene was excluded as a candidate for myopia 2
(MYP2), but the SNPs detected in this study will aid in future
mapping and association studies involving this gene.
REFERENCE 9 (bases 1 to 6245)
AUTHORS Peterfy M, Phan J, Xu P and Reue K.
TITLE Lipodystrophy in the fld mouse results from mutation of a new gene
encoding a nuclear protein, lipin
JOURNAL Nat. Genet. 27 (1), 121-124 (2001)
PUBMED 11138012
REFERENCE 10 (bases 1 to 6245)
AUTHORS Lehner R and Kuksis A.
TITLE Biosynthesis of triacylglycerols
JOURNAL Prog. Lipid Res. 35 (2), 169-201 (1996)
PUBMED 8944226
REMARK Review article
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC152448.1, AP000919.6 and
BQ014306.1.
On Jul 31, 2002 this sequence version replaced gi:7662021.
Summary: Mouse studies suggest that this gene functions during
normal adipose tissue development and may play a role in human
triglyceride metabolism. This gene represents a candidate gene for
human lipodystrophy, characterized by loss of body fat, fatty
liver, hypertriglyceridemia, and insulin resistance. [provided by
RefSeq, Jul 2008].
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC152448.1, D87436.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-2932 BC152448.1 1-2932
2933-6069 AP000919.6 98438-101574 c
6070-6245 BQ014306.1 1-176 c
FEATURES Location/Qualifiers
source 1..6245
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18p11.31"
gene 1..6245
/gene="LPIN2"
/note="lipin 2"
/db_xref="GeneID:9663"
/db_xref="HGNC:14450"
/db_xref="HPRD:16114"
/db_xref="MIM:605519"
exon 1..230
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
misc_feature 219..221
/gene="LPIN2"
/note="upstream in-frame stop codon"
exon 231..431
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
CDS 240..2930
/gene="LPIN2"
/EC_number="3.1.3.4"
/note="lipin-2"
/codon_start=1
/product="phosphatidate phosphatase LPIN2"
/protein_id="NP_055461.1"
/db_xref="GI:7662022"
/db_xref="CCDS:CCDS11829.1"
/db_xref="GeneID:9663"
/db_xref="HGNC:14450"
/db_xref="HPRD:16114"
/db_xref="MIM:605519"
/translation="
MNYVGQLAGQVIVTVKELYKGINQATLSGCIDVIVVQQQDGSYQCSPFHVRFGKLGVLRSKEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKDIDTPLVKSGGDETPSQSSDISHVLETETIFTPSSVKKKKRRRKKYKQDSKKEEQAASAAAEDTCDVGVSSDDDKGAQAARGSSNASLKEEECKEPLLFHSGDHYPLSDGDWSPLETTYPQTACPKSDSELEVKPAESLLRSESHMEWTWGGFPESTKVSKRERSDHHPRTATITPSENTHFRVIPSEDNLISEVEKDASMEDTVCTIVKPKPRALGTQMSDPTSVAELLEPPLESTQISSMLDADHLPNAALAEAPSESKPAAKVDSPSKKKGVHKRSQHQGPDDIYLDDLKGLEPEVAALYFPKSESEPGSRQWPESDTLSGSQSPQSVGSAAADSGTECLSDSAMDLPDVTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWALAAPMILSLQVFQKSLPKATVESWVKDKMPKKSGRWWFWRKRESMTKQLPESKEGKSEAPPASDLPSSSKEPAGARPAENDSSSDEGSQELEESITVDPIPTEPLSHGSTTSYKKSLRLSSDQIAKLKLHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKIIISDIDGTITKSDALGQILPQLGKDWTHQGIAKLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSKQPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSAFPCPEFSSFCYWRDPIPEVDLDDLS
"
misc_feature 240..581
/gene="LPIN2"
/note="lipin, N-terminal conserved region; Region:
Lipin_N; pfam04571"
/db_xref="CDD:113346"
misc_feature 240..563
/gene="LPIN2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
Region: N-LIP"
misc_feature 696..713
/gene="LPIN2"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
Region: Nuclear localization signal (Potential)"
misc_feature 966..968
/gene="LPIN2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2142..2750
/gene="LPIN2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
Region: C-LIP"
misc_feature 2292..2762
/gene="LPIN2"
/note="This domain is found in Saccharomyces cerevisiae
protein SMP2, proteins with an N-terminal lipin domain and
phosphatidylinositol transfer proteins; Region: LNS2;
smart00775"
/db_xref="CDD:197870"
misc_feature 2292..2762
/gene="LPIN2"
/note="LNS2 (Lipin/Ned1/Smp2); Region: LNS2; pfam08235"
/db_xref="CDD:149348"
misc_feature 2304..2318
/gene="LPIN2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
Region: DXDXT motif"
misc_feature 2337..2351
/gene="LPIN2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q92539.1);
Region: LXXIL motif"
exon 432..527
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 528..829
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 830..937
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 938..1061
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 1062..1407
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 1408..1507
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 1508..1695
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
variation 1649
/gene="LPIN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:35932462"
exon 1696..1789
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 1790..1859
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 1860..1949
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 1950..2032
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 2033..2177
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 2178..2326
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 2327..2413
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 2414..2566
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 2567..2681
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 2682..2785
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
exon 2786..6229
/gene="LPIN2"
/inference="alignment:Splign:1.39.8"
variation 2933
/gene="LPIN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3745012"
variation 3615
/gene="LPIN2"
/replace="a"
/replace="t"
/db_xref="dbSNP:607549"
variation 3727
/gene="LPIN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:3810064"
variation 3877..3878
/gene="LPIN2"
/replace=""
/replace="a"
/db_xref="dbSNP:3840906"
variation 3880
/gene="LPIN2"
/replace="a"
/replace="c"
/db_xref="dbSNP:3810065"
STS 4088..4189
/gene="LPIN2"
/standard_name="A006I48"
/db_xref="UniSTS:54966"
STS 4773..5086
/gene="LPIN2"
/standard_name="SHGC-82401"
/db_xref="UniSTS:104544"
variation 4900
/gene="LPIN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:13286"
STS 4918..5836
/gene="LPIN2"
/standard_name="LPIN2_8975"
/db_xref="UniSTS:468080"
STS 5037..5161
/gene="LPIN2"
/standard_name="RH46193"
/db_xref="UniSTS:39071"
variation 5192
/gene="LPIN2"
/replace="g"
/replace="t"
/db_xref="dbSNP:1803421"
STS 5469..5617
/gene="LPIN2"
/standard_name="WI-15441"
/db_xref="UniSTS:78278"
variation 5853
/gene="LPIN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202079191"
variation 5876
/gene="LPIN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:4781"
STS 5918..6189
/gene="LPIN2"
/standard_name="G60225"
/db_xref="UniSTS:137336"
STS 5934..6118
/gene="LPIN2"
/standard_name="WIAF-1505"
/db_xref="UniSTS:56326"
variation 5938
/gene="LPIN2"
/replace="c"
/replace="g"
/db_xref="dbSNP:10937"
variation 5945
/gene="LPIN2"
/replace="c"
/replace="t"
/db_xref="dbSNP:14916"
STS 5977..6160
/gene="LPIN2"
/standard_name="RH8145"
/db_xref="UniSTS:92218"
STS 5990..6161
/gene="LPIN2"
/standard_name="WIAF-2076"
/db_xref="UniSTS:20577"
variation 5998
/gene="LPIN2"
/replace="a"
/replace="t"
/db_xref="dbSNP:1985"
STS 6042..6192
/gene="LPIN2"
/standard_name="HSC1YH092"
/db_xref="UniSTS:80896"
variation 6069
/gene="LPIN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1164"
variation 6194
/gene="LPIN2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1803420"
polyA_signal 6204..6209
/gene="LPIN2"
polyA_site 6229
/gene="LPIN2"
ORIGIN
gagaagaagtggcaggtgatgctgaagcgggggagaagcggcagagccggccacacagtgcaggggatggagacaggtgctgggctggtcctcctgcagcatcctcagttgttggagggcagtcatcctcaggccgtacccagccagagaagaaaaagaacagtgtgaagccacgtgtgatagccgtccaacatcggctcttccctccaattacattgtagttgattgtgtctcaaaccatgaattatgtgggacagctggctgggcaggtgattgtcactgtgaaggaactctacaagggcattaaccaggccaccctctctgggtgcattgatgtcatcgtggtacagcagcaggatggcagctatcagtgttcaccttttcacgttcggtttggaaagctgggagtcctgagatccaaagagaaagtgattgatatagaaatcaacggcagtgcagtggatcttcacatgaagttgggtgataacggagaagctttctttgttgaggagactgaagaagaatatgaaaagcttcctgcttaccttgccacctcaccaattcctactgaagatcagttctttaaagatattgacacccctttggtgaaatcgggtggagatgaaacaccatctcagagttcagacatctcacacgtcttggaaacagagacaatttttactccaagttctgtgaaaaagaaaaaacgaaggagaaagaaatacaaacaggacagtaagaaggaagagcaggccgcatctgctgctgcagaagacacatgtgatgtaggcgtgagctccgatgatgacaagggggcccaggcagcacgaggatcttcaaatgcttccttgaaagaagaagaatgtaaagagcctttgctcttccattctggggatcattaccccttatctgatggagattggtcccctttagagaccacctatccccagacagcgtgtcctaagagtgattcagagctggaggtgaaacctgcggagagcctgctcagatcagagtctcacatggagtggacgtggggcggattcccagagtccaccaaggtcagcaaaagagaacgatctgaccatcatcctaggacagctacaattacaccatcagaaaatactcattttcgggtaattcccagtgaggacaacctcatcagtgaagttgagaaggatgcttccatggaagacactgtctgtaccatagtgaagcccaaacccagagccctgggtacacagatgagcgacccaacatctgtggcagagcttctcgaacctcctcttgagagtactcagatttcatctatgttagatgctgaccaccttcccaacgcagccttagcggaggcgccctcagaatccaaaccggcagctaaagtagactcgccgtcaaagaagaaaggtgttcacaaaagaagccaacaccagggacctgatgatatttaccttgatgacttaaagggtctagaacctgaagttgcagctctttatttccctaaaagtgaatcggagcccggttccaggcagtggcccgagtctgacacactctctggctcccagtccccacagtccgtgggaagcgcagctgcagatagcggcaccgagtgcctctcagattctgccatggacttgcctgacgttaccctctccctttgcgggggcctcagtgaaaatggagaaatttcaaaagaaaaattcatggagcatatcattacttatcacgaatttgcagaaaaccctggacttatagacaatcctaaccttgtaataaggatatataatcgttactataactgggctttggcagctcccatgatccttagcttgcaagtattccagaagagcttgcctaaggccacagttgagtcctgggtgaaagacaagatgccaaagaaatctggtcgctggtggttttggcgaaagagagaaagcatgaccaaacagctgccagaatccaaggagggaaaatctgaggcaccgccagccagtgacctgccatccagctccaaggagccggccggtgccaggccggccgagaatgactcctcgagtgacgagggatcacaggagctcgaagaatccatcacagtggaccccatccccacagagcccctgagccacggcagcacaacttcatataagaagtctctccgcctctcctcagaccagatcgcaaaactgaagctccacgatggcccaaatgatgttgtgtttagtattacaacccagtatcaaggcacctgtcgctgtgcagggaccatttacctgtggaactggaatgacaagatcatcatttctgatattgatgggacaataaccaagtcggatgctttgggacagattctcccacagctgggcaaagactggacccaccagggtatagcaaagctctaccattccatcaatgagaatggctacaagtttctgtactgctcggctcgtgccatcggcatggccgacatgacccgtggctacctgcactgggtcaatgacaagggcacaatcttgccccggggccccctgatgctgtcccccagcagcttgttctccgccttccacagagaagtgatagaaaagaaaccagagaagttcaaaattgagtgtctaaatgatatcaagaatctgtttgccccgtctaagcagcccttctatgctgcctttggaaaccgtccaaatgatgtctatgcctacacacaagttggagttccagactgtagaatattcaccgtgaaccccaagggtgaattaatacaagaaagaaccaaaggaaacaagtcatcgtatcacaggctgagtgagctcgtggagcatgtgttcccccttctcagtaaggagcagaattccgcttttccctgcccggagttcagctccttctgctactggcgagacccgatccctgaagtggacctggatgacctgtcttgaggcggcacctcagtgggtgggcagggcttggtccccctccccacagcaagggaaggcagctggctcttctgctgacctcagataccagccttccccagcggggacgggtgcttctggagctggtcccgccatcctcctttgccttcccaggccagctgctcaggctcggcaggtctgcagctcagctcctggaaggagaagggaggaactgggcctggggctggaggcctgggatccctcctttgtgggtcgcacacatgtttcctgctgtgagctggggcctccttccattgcatcattttaaaggaagaaaaaagcagctaaaaaagagtggaccaaaacactgcacacagtgaagtgttccagtttccactgggcagttgaggtggcttctgtaaccagggctgtcttcagatgtcagggtccctgaactgctgcgggcccagtcagtgatgctggctgaagctgcctgtgcacgtttcttctctggtcgcctcatttcctgctacactgaaggggtcagctgctccagtgggccaagttgggcaggacccccgcccctgcagggcccatgcaccagagccactgagcccagtcccataaacctggccctctttggggaaagatccccacagagcatcctcctctcatctgtgacaactccacgagcccttaatttcttagtcctcaccagaagaacaggtctcacaagtatatatttgatgtctgtaataaaagtgggaaggtgggtcttaaaacagaccaaaccccgccccgcccccaacaactctgcttttagggaggcctccgaaatgcagataggcggttgagtggggtcctgggaagagcgctgaatccctctgcttgctgcctggtgtgggcctttggaaagcatcttgccttgggacaggatttctaaaattctgtgattcagatttgtcagggaagcacagtgaagcttgcttaaaggcactggccagcagtgtgtgactttggcttttgggatcacaccctgtaatcgggcccgtggaagcagcgtcaaagaggggtcttggagctcctatggagcagactgccccccgagcagtgtccccagcctagccctgtgagaccccatggggacacgggtgcctatgtattttcactaaaatatacatggtagctccatttactgatgcggttgtaatgagctcacatcgtgtctgaagagatggcaccagggaaaggtgtgccataagctgctccagagcttttggtatgctgagtgttgacagagctgcactcttaacatcaagagaactgtcaggagcccagaaccaaccccaggtcttggtctccattggcgagaacacaggacgtggtggttcctgagcagagagggatctgcagatacaggcttggcgctcggggtggtctcgtggccaactcttcatgcccctgccgttgtagtggaacctctacatgttttagtttgcttcacctaaaataatgctgatctagagatagagaaataggggtggttatttttccagattggagagttgaaagtccctgactgatttcagccattttcctagtgcttgtcggatgcagagacaatgttgaaatcccctaaacacagttctcagtggcaaaacctaggaaggctcatgttcccagagaagggaccacatgagccttctcccatgcaaagcttcccccagcttaaatagttgataaggactaattgtttaatgagtttatttatctacagtaggttagggatcctgggttctgtttatatgaagttcttcccagtttgtgaattctagtacagcagccatgcagccaccttatttcatagatgccatctgtgtgtcctcttgactaccttctatttagaggaagaatgagagctttgtgtgtttaactgagcttatagtaggacttctttgcatatgtatggtactgaaaaatcttaatatacatctttaatcctttttaggttgtcctttaaagagtttttgactagtttctttttcttgacagctcttctctttggacacatgggccttcttagagggttcagtctaggacccggctctcctggccctgtgttgagggtagctggtccctctgtccctgtgtctgctagcactagactttgttgctgcagattgatccagtgggtacataggctaattaatgtgagtctttttccttgtttaaaggagtccctcttgctgaaagtagatgattactattgctgtagtgttaggaaagtattaagtttgtgctgaaaatccattgccatttggtacaaatgacatttgttctttctgtgaaagagatgccctcgagtgtgtttgtacacaaacccttaggatggtgagttgaagcatcaccctcgcgctatcttcagtgacgggtgacggctcagggagatggcaggcagattgggctctaagtcattattctctcagttactccattggtgaaatggccctttccctctttgcagttcagtctaagtctcgtatttgctttgctgtctgtgtgctgaagctcgtcccgtgtgagttgctgtctgccccttgtcaggctgtgaggtgctcgtgtagacctggagcatgcaggctgcctccgtttttgggtactgtgttgtgttttgctctgtctaaaaacatctgcatagttttcaactggaaaaagaaaaaacttaaaaatgggatgtcctaaaatgaaagctgctcaaagtcacagaacaaccgagggacaaaggagattggatgactgggaagcgctggcccggaacagcccctgcaactgtggggcctgcacacagcccttccacagttggcactgcaggtgcaggccaaccctttaaagaataaacaaggaagtcagctctttcactttttacaagttggcaaaaacagacttccggggaatttcgatgttttcccgtgttgtagagcttccagggtttaataaaactggttaaaaattgagtctttccctgaagtaagtgctctttccagatgaaaactactcttttggttttgtttgaaagtaagaaagggaggggaaactttgctcttttaataattatgttcagcctatgatgaagtatttgattattagacagcaatgtcactaataagttttaagttgtccaaagttaattgtaaacatcatcagtacagtactcttagttacagtaaagcaattgttgcaagatgaatggctaatattttggtgcagtgtttgatgttcaaaacaaaatgttacaacaataaacgaacataacataaactgaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9663 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: ISS
GeneID:9663 -> Molecular function: GO:0008195 [phosphatidate phosphatase activity] evidence: ISS
GeneID:9663 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:9663 -> Biological process: GO:0006629 [lipid metabolic process] evidence: ISS
GeneID:9663 -> Biological process: GO:0006631 [fatty acid metabolic process] evidence: IEA
GeneID:9663 -> Biological process: GO:0006644 [phospholipid metabolic process] evidence: TAS
GeneID:9663 -> Biological process: GO:0006646 [phosphatidylethanolamine biosynthetic process] evidence: TAS
GeneID:9663 -> Biological process: GO:0006656 [phosphatidylcholine biosynthetic process] evidence: TAS
GeneID:9663 -> Biological process: GO:0019432 [triglyceride biosynthetic process] evidence: TAS
GeneID:9663 -> Biological process: GO:0044255 [cellular lipid metabolic process] evidence: TAS
GeneID:9663 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
GeneID:9663 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: ISS
GeneID:9663 -> Biological process: GO:0046474 [glycerophospholipid biosynthetic process] evidence: TAS
GeneID:9663 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
GeneID:9663 -> Cellular component: GO:0005789 [endoplasmic reticulum membrane] evidence: TAS
GeneID:9663 -> Cellular component: GO:0005829 [cytosol] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_055461 -> EC 3.1.3.4
by
@meso_cacase at
DBCLS
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