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2025-05-09 18:24:19, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_014720 5629 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens STE20-like kinase (SLK), mRNA.
ACCESSION NM_014720
VERSION NM_014720.2 GI:41281452
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5629)
AUTHORS Viswanatha,R., Ohouo,P.Y., Smolka,M.B. and Bretscher,A.
TITLE Local phosphocycling mediated by LOK/SLK restricts ezrin function
to the apical aspect of epithelial cells
JOURNAL J. Cell Biol. 199 (6), 969-984 (2012)
PUBMED 23209304
REMARK GeneRIF: It was shown that lymphocyte-oriented and STE20 kinase
were sufficient to restrict ezrin function to the apical domain.
Both kinases were enriched in microvilli and locally activated
there.
REFERENCE 2 (bases 1 to 5629)
AUTHORS Cha,P.C., Takahashi,A., Hosono,N., Low,S.K., Kamatani,N., Kubo,M.
and Nakamura,Y.
TITLE A genome-wide association study identifies three loci associated
with susceptibility to uterine fibroids
JOURNAL Nat. Genet. 43 (5), 447-450 (2011)
PUBMED 21460842
REFERENCE 3 (bases 1 to 5629)
AUTHORS Roovers,K., Wagner,S., Storbeck,C.J., O'Reilly,P., Lo,V.,
Northey,J.J., Chmielecki,J., Muller,W.J., Siegel,P.M. and
Sabourin,L.A.
TITLE The Ste20-like kinase SLK is required for ErbB2-driven breast
cancer cell motility
JOURNAL Oncogene 28 (31), 2839-2848 (2009)
PUBMED 19525980
REMARK GeneRIF: Studies define an interaction between Neu and SLK
signaling in the regulation of cancer cell motility.
REFERENCE 4 (bases 1 to 5629)
AUTHORS Burakov,A.V., Zhapparova,O.N., Kovalenko,O.V., Zinovkina,L.A.,
Potekhina,E.S., Shanina,N.A., Weiss,D.G., Kuznetsov,S.A. and
Nadezhdina,E.S.
TITLE Ste20-related protein kinase LOSK (SLK) controls microtubule radial
array in interphase
JOURNAL Mol. Biol. Cell 19 (5), 1952-1961 (2008)
PUBMED 18287541
REMARK GeneRIF: Protein kinase LOSK is required for radial microtubule
organization and for the proper localization of Golgi complex in
various cell types.
REFERENCE 5 (bases 1 to 5629)
AUTHORS Pike,A.C., Rellos,P., Niesen,F.H., Turnbull,A., Oliver,A.W.,
Parker,S.A., Turk,B.E., Pearl,L.H. and Knapp,S.
TITLE Activation segment dimerization: a mechanism for kinase
autophosphorylation of non-consensus sites
JOURNAL EMBO J. 27 (4), 704-714 (2008)
PUBMED 18239682
REFERENCE 6 (bases 1 to 5629)
AUTHORS Nakayama,M., Kikuno,R. and Ohara,O.
TITLE Protein-protein interactions between large proteins: two-hybrid
screening using a functionally classified library composed of long
cDNAs
JOURNAL Genome Res. 12 (11), 1773-1784 (2002)
PUBMED 12421765
REFERENCE 7 (bases 1 to 5629)
AUTHORS Dan,I., Watanabe,N.M. and Kusumi,A.
TITLE The Ste20 group kinases as regulators of MAP kinase cascades
JOURNAL Trends Cell Biol. 11 (5), 220-230 (2001)
PUBMED 11316611
REFERENCE 8 (bases 1 to 5629)
AUTHORS Eichmuller,S., Usener,D., Dummer,R., Stein,A., Thiel,D. and
Schadendorf,D.
TITLE Serological detection of cutaneous T-cell lymphoma-associated
antigens
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 98 (2), 629-634 (2001)
PUBMED 11149944
REFERENCE 9 (bases 1 to 5629)
AUTHORS Yamada,E., Tsujikawa,K., Itoh,S., Kameda,Y., Kohama,Y. and
Yamamoto,H.
TITLE Molecular cloning and characterization of a novel human STE20-like
kinase, hSLK
JOURNAL Biochim. Biophys. Acta 1495 (3), 250-262 (2000)
PUBMED 10699464
REFERENCE 10 (bases 1 to 5629)
AUTHORS Sabourin,L.A., Tamai,K., Seale,P., Wagner,J. and Rudnicki,M.A.
TITLE Caspase 3 cleavage of the Ste20-related kinase SLK releases and
activates an apoptosis-inducing kinase domain and an
actin-disassembling region
JOURNAL Mol. Cell. Biol. 20 (2), 684-696 (2000)
PUBMED 10611247
REMARK Erratum:[Mol Cell Biol 2000 Apr;20(8):2949]
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from AF273048.1.
On Jan 25, 2004 this sequence version replaced gi:7661993.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF273048.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025086 [ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..5629
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q24.33"
gene 1..5629
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="STE20-like kinase"
/db_xref="GeneID:9748"
/db_xref="HGNC:11088"
/db_xref="HPRD:11585"
misc_feature 1..5629
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="sequence similar to KIAA0204in Accession Number
D86959 and to partial sequence of chromosome 10 in
Accession Number AL138761"
exon 1..184
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 17
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:200364911"
CDS 35..3742
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/EC_number="2.7.11.1"
/note="Long Ste20-like Kinase; Ste20-related
serine/threonine kinase; CTCL tumor antigen se20-9; hSLK;
STE20-related kinase; serine/threonine-protein kinase 2;
STE20-related serine/threonine-protein kinase; SNF1
sucrose nonfermenting like kinase; SNF1 (sucrose
nonfermenting, yeast, homolog)-like kinase, SNF1 sucrose
nonfermenting like kinase"
/codon_start=1
/product="STE20-like serine/threonine-protein kinase"
/protein_id="NP_055535.2"
/db_xref="GI:41281453"
/db_xref="CCDS:CCDS7553.1"
/db_xref="GeneID:9748"
/db_xref="HGNC:11088"
/db_xref="HPRD:11585"
/translation="
MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS
"
misc_feature 74..76
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 116..946
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="Catalytic domain of the Protein Serine/Threonine
Kinase, Ste20-like kinase; Region: STKc_SLK; cd06643"
/db_xref="CDD:132974"
misc_feature 134..910
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="Serine/Threonine protein kinases, catalytic domain;
Region: S_TKc; smart00220"
/db_xref="CDD:197582"
misc_feature order(152..166,176..178,215..217,221..223,269..271,
308..310,350..352,356..367,374..379,386..388,497..499,
503..514,518..520,548..553,560..562,602..613,617..619,
713..715,740..742)
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="active site"
/db_xref="CDD:132974"
misc_feature order(152..166,176..178,215..217,221..223,269..271,
308..310,350..352,356..367,374..379,386..388,509..514,
518..520,548..553)
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:132974"
misc_feature order(161..166,497..499,503..511,560..562,602..613,
617..619,713..715,740..742)
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:132974"
misc_feature 548..619
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="activation loop (A-loop); other site"
/db_xref="CDD:132974"
misc_feature 599..601
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 599..601
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1022..1024
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 1052..1054
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1055..1057
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1064..1066
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 1064..1066
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1073..1075
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 1073..1075
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1076..1078
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 1076..1078
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1076..1078
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1094..1096
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1346..1351
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="non-experimental evidence, no additional
details recorded"
/note="Cleavage, by caspase-3 (By similarity); propagated
from UniProtKB/Swiss-Prot (Q9H2G2.1); cleavage site"
misc_feature 1727..1729
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 1745..1747
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 1997..1999
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 2363..2365
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 2369..2371
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 2486..2488
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9H2G2.1); phosphorylation site"
misc_feature 3119..3514
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/note="Polo kinase kinase; Region: PKK; pfam12474"
/db_xref="CDD:204935"
misc_feature 3323..3325
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (Q9H2G2.1); phosphorylation site"
variation 35
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="a"
/db_xref="dbSNP:67005250"
variation 48
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150455513"
variation 61
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201104748"
variation 66
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:202109385"
variation 89
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:137997569"
variation 133
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:149480041"
variation 183
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201954327"
exon 185..349
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 204
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113216800"
exon 350..398
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 383
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:11191893"
variation 398
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:80262674"
exon 399..548
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 433
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184400051"
variation 451
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56287824"
variation 536
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144641250"
variation 544
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138539059"
exon 549..621
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 562
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:10883960"
exon 622..816
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 638
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146276432"
variation 727
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148478778"
variation 754
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376604412"
variation 758
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200677132"
variation 763
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:55977639"
variation 794
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:199953246"
exon 817..898
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 821
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200335070"
variation 893
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:150555883"
exon 899..1027
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 928
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:55893133"
variation 1000
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139324300"
variation 1015
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369850873"
variation 1017
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145464859"
exon 1028..2383
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 1033
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147685845"
variation 1047
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201543977"
variation 1053
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:373397561"
variation 1112
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:143489434"
variation 1133
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201028021"
variation 1138
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373285860"
variation 1139
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140715399"
variation 1151
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199730741"
variation 1241
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200759996"
variation 1252
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200580260"
variation 1254
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201455950"
variation 1266
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372744623"
variation 1297
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144609785"
variation 1299
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:199864933"
variation 1347
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:201945425"
variation 1368
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377170080"
variation 1398
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368834488"
variation 1428
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145891003"
variation 1460
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:181201567"
variation 1505
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="a"
/db_xref="dbSNP:66960104"
variation 1512
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374158573"
variation 1538
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200940208"
variation 1593
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371702036"
variation 1597
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375320590"
variation 1600
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:369382208"
variation 1606
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199501020"
variation 1609
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:373232158"
variation 1636
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:185852639"
variation 1637
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199902178"
variation 1641
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:149001506"
variation 1671
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143783348"
variation 1689
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:805657"
variation 1740
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:141030799"
variation 1741
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:56357599"
variation 1752
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138561931"
variation 1778
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:202126066"
variation 1844
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:190220654"
variation 1911
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199510176"
variation 1934
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375427458"
variation 2007
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:56400929"
variation 2020
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:74154716"
variation 2031
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:7071400"
variation 2043
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:117017856"
variation 2048
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375867060"
variation 2070
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:34326537"
variation 2083
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:35389916"
variation 2113
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:144105969"
variation 2124
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3740469"
variation 2179
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368294178"
variation 2224..2225
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="a"
/replace="aa"
/db_xref="dbSNP:35535114"
variation 2237
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372263493"
variation 2276
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:142780049"
variation 2288
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:376822140"
variation 2301
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201226890"
variation 2370
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:187213555"
variation 2371
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375037120"
exon 2384..2514
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 2394
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:193020197"
variation 2396
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:376190522"
variation 2408
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147274773"
variation 2419
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368748580"
variation 2434
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371482953"
variation 2455..2456
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="c"
/db_xref="dbSNP:35824206"
variation 2458..2459
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="c"
/db_xref="dbSNP:35910700"
variation 2492
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="a"
/db_xref="dbSNP:66656992"
variation 2495
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140813954"
variation 2506
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:116628156"
exon 2515..2638
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 2521
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:56261739"
variation 2569
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369557083"
variation 2572
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201110021"
variation 2580
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373027455"
variation 2590
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:805662"
variation 2600
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:376478203"
variation 2601
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138865314"
variation 2608
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370047288"
variation 2633
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138028690"
exon 2639..2818
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 2722
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376977945"
variation 2741
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:139235638"
variation 2752
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150068060"
variation 2754
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112147254"
exon 2819..2911
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 2827
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:145383503"
variation 2853
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371469996"
variation 2873
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373815490"
variation 2874
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141355740"
exon 2912..3041
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 2959
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199577733"
variation 2967
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="t"
/db_xref="dbSNP:143790863"
variation 3027
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:372778251"
exon 3042..3166
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 3083
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:202174450"
variation 3151
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:367939267"
exon 3167..3355
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 3178
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146708638"
variation 3186
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373118126"
variation 3317
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201228187"
exon 3356..3481
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 3373
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140276120"
variation 3379
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:55914158"
variation 3395
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:55708299"
variation 3428
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147985366"
variation 3463
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377591796"
variation 3472
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150167438"
variation 3474
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370580979"
exon 3482..3595
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 3509
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138622989"
variation 3510
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201270634"
variation 3546
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199725906"
variation 3551
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:142839532"
variation 3561
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:147399386"
variation 3583
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:368550353"
exon 3596..5606
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/inference="alignment:Splign:1.39.8"
variation 3656
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:61861275"
variation 3733
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139177471"
variation 3736
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199817641"
variation 3739
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:143127472"
variation 3762
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192363594"
variation 3763
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:182458142"
variation 3766
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184996484"
variation 3881
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="t"
/db_xref="dbSNP:72044204"
variation 3918
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:143144952"
variation 4021..4022
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="tgaa"
/db_xref="dbSNP:143875505"
variation 4022..4023
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="tgaa"
/db_xref="dbSNP:71717068"
variation 4177
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:11191898"
variation 4295
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147477212"
variation 4346
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139919327"
variation 4400
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41287518"
variation 4455
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:74154720"
variation 4512
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189872426"
variation 4562
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:805684"
variation 4654
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:182514725"
variation 4685
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377187237"
variation 4712
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374733105"
variation 4726
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45597434"
variation 4764
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:2902640"
variation 4807
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:809303"
variation 4881
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:145155087"
variation 4898
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45559432"
variation 5030
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="g"
/db_xref="dbSNP:75214523"
variation 5078
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:187023559"
variation 5106
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192820921"
variation 5227
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="c"
/db_xref="dbSNP:1803467"
STS 5237..5356
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/standard_name="RH25417"
/db_xref="UniSTS:88178"
variation 5276
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="g"
/replace="t"
/db_xref="dbSNP:183728611"
variation 5367
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace=""
/replace="t"
/db_xref="dbSNP:147186541"
variation 5503
/gene="SLK"
/gene_synonym="bA16H23.1; LOSK; se20-9; STK2"
/replace="a"
/replace="g"
/db_xref="dbSNP:188657821"
ORIGIN
cttaagtgcaaggaactctgtgttgggaggaaaaatgtccttcttcaatttccgtaagatcttcaagttggggagcgagaagaagaagaagcagtacgaacacgtgaagagggacctgaaccccgaagacttttgggagattataggagaactgggcgacggagcctttgggaaagtgtacaaggcccagaataaagagaccagtgttttagctgctgcaaaagtgattgacactaaatctgaagaagaacttgaagattacatggtagagattgacatattagcatcttgtgatcacccaaatatagtcaagcttctagatgccttctattatgagaacaatctttggatcctcattgaattttgtgcaggtggagcagtagatgctgtgatgcttgaacttgagagaccattaactgagtcccaaatacaagtagtttgcaagcagactttagatgcattgaactacttacatgataataagatcatccacagagatctgaaggctggcaacattctctttaccttagatggagatatcaaattggcggattttggagtatcagctaaaaacacgaggacaattcaaagaagagattcctttattggtacaccatattggatggctcctgaagtagtcatgtgtgaaacatctaaggacagaccctatgactacaaagctgatgtttggtccctgggtatcactttaatagaaatggctgagatagaaccacctcatcatgaattaaatccaatgcgagtgctgctaaaaatagcaaaatctgagccacctacattagcacagccatccagatggtcttcaaattttaaggactttctaaagaaatgcttagaaaagaatgtggatgccaggtggactacatctcagctgctgcagcatccctttgttactgttgattccaacaaacccatccgagaattgattgcagaggcgaaggctgaagtaacagaagaagttgaagatggcaaagaggaagatgaagaggaggaaacagaaaattctctgccaatacctgcaagtaagcgtgcatcttctgaccttagtatcgccagctctgaagaagataaactttcacaaaatgcttgtattttggagtctgtctcagaaaaaacagaacgtagtaactctgaagataaactcaacagcaaaattcttaatgaaaaacccaccactgatgaacctgaaaaggctgtggaggatattaatgaacatattaccgatgctcagttagaagcaatgactgaactccatgacagaacagcagtaatcaaggagaatgaaagagagaagaggcccaagcttgaaaatctgcctgacacagaagaccaagaaactgtggacattaattcagtcagtgaaggaaaagagaataatataatgataaccttagaaacaaatattgaacataatctaaaatctgaggaagaaaaggatcaggaaaagcaacagatgtttgaaaataagcttataaaatctgaagaaattaaagatactattttgcaaacagtagatttagtttctcaagagactggagaaaaagaggcaaatattcaggcagttgatagtgaagttgggcttacaaaggaagacacccaagagaaattgggggaagacgacaaaactcaaaaagatgtgatcagcaatacaagtgatgtgataggaacatgtgaggcagcagatgtggctcagaaagtggatgaagacagtgctgaggatacgcagagtaatgatgggaaagaagtggtcgaagtaggccagaaattaattaataagcccatggtgggtcctgaggctggtggtactaaggaagttcctattaaagaaatagttgaaatgaatgaaatagaagaaggtaaaaataaggaacaagcaataaacagttcagagaacataatggacatcaatgaggaaccaggaacaactgaaggtgaagaaatcactgagtcaagtagcactgaagaaatggaggtcagaagtgtggtggctgatactgaccaaaaggctttaggaagtgaagttcaggatgcttctaaagtcactactcagatagataaagagaaaaaagaaattccagtgtcaattaaaaaagagcctgaagttactgtagtttcacagcccactgaacctcagcctgttctaatacccagtattaatatcaactctgacagtggagaaaataaagaagaaataggttctttatcaaaaactgaaactattctgccaccagaatctgagaatccaaaggaaaatgataatgattcaggcactggttccactgctgatactagcagtattgacttgaatttatccatctctagctttctaagtaaaactaaagacagtggatcgatatctttacaagaaacaagaagacaaaagaaaacattgaagaaaacacgcaaatttattgttgatggtgtagaagtgagtgtaacaacatcaaagatagttacagatagtgattccaaaactgaagaattgcggtttcttagacgtcaggaacttcgggaattaagatttcttcagaaagaagagcaaagagcccaacaacagctcaatagcaaactacagcaacaacgagaacaaattttccggcgctttgagcaggaaatgatgagtaaaaagcgacaatatgaccaggaaattgagaatctagaaaaacagcagaaacagactatcgaacgcctggaacaagagcacacaaatcgcttgcgagatgaagccaaacgcatcaaaggagaacaagagaaagagttgtccaaatttcagaatatgctgaagaaccgaaagaaggaggttataaatgaagtggagaaagcacccaaagagctgagaaaagagctcatgaaacgcaggaaagaggagcttgcacaaagccagcatgctcaggaacaagagtttgttcagaaacaacagcaagaattagatggctctctgaaaaagatcatccagcagcagaaggcagagttagctaatattgagagagagtgcctgaataacaagcaacagctcatgagagctcgagaagctgcaatttgggagctcgaagaacgacacttacaagaaaaacaccagctgctcaaacagcagcttaaagatcagtatttcatgcaaagacatcagctacttaagcgccacgagaaggaaacagagcaaatgcagcgttacaatcaaagacttattgaggaattgaaaaacagacagactcaagaaagagcaagactgcccaagattcagcgcagtgaagccaagactcgaatggccatgtttaagaagagtttgagaattaactcaacagccacaccagatcaggaccgtgataaaattaaacagtttgctgcacaagaagaaaagaggcagaaaaatgagagaatggctcagcatcagaaacatgagaatcaaatgcgagatcttcagttgcagtgtgaagccaatgtccgcgaactgcatcagctgcagaatgaaaaatgccacttgttggttgagcatgagactcagaaactgaaggagttagatgaggaacatagccaagaattaaaggagtggagagagaaattgagacctaggaaaaagacactggaagaagagtttgccaggaaactacaggaacaggaagtattctttaaaatgactggggagtctgaatgccttaacccatcaacacagagccggatttccaaattttatcctattcccagcttgcattccaccggatcataacaaagggaagcattctgtgcgtgggtttggctctttcagtatgtcattctgttctcatcttctgccacagtctctcagatagctcatgaagacaatcacctgcctcaccttctaggtgttttccttttttgttttttttgttttgttttgtttttaagcaaagatgaagggaaaacgaactaagacagacgctaggccatgttggcaaagtagcatcttggtgactaaggtgactttgtatattcatcttaaaaattatgttctttagacactgctacctgaaaactgttggagaaataatgtttaaagttatttaagaaaaactgttacatcactaagtattaataaattcttcttacctgacgtaacttctcaatgcctaaattctgtagttgaagctctgctgcagagagttgggataattttcttttggtggatcagctctcataaaaaagctatgatttgctcaaatatgctgttgactcagtaaatgaatatatttttttctttaaataggaacaacctcttttaaaagagaaaaattatttcagtgatttgtcaaaacgaattacctcttttggcatgagctaataattgagggtgctaattttcttaagatagtgcctaaaacactaaatttcagtcaagtcgtaagtaggattttctttttgatcaacagggacaaaaacatctttagaattaaaaacatggttgttttggaatttttgcttctcttaccgtttgatagaaattttcatcctaaaatacatgtacaaagtttggaaagatgaaaaaaagaggtagcttttagattgcaaattggaaatgtaaaactcatgaaatttaagcaatataggtttagctatctgtgtttattttctaaaataatacctgagctggttaaatgatttctctccatcttagctaattctgtttaaaactctgtcagaggcctgcaggctgtgagttatatttataaatatatcttcagaaattaatcttaaaagaggcattagttcagaatacttttttaaaagtttaaattaaatatttaggcacgtcagaaattacttttccttattttgaaatgaggctacttatgtcttggttttattttgttccatgtttaaatcattcactttgatttgagtgggaaaagcctgaagcctttatcatgtggttgctggtgtgtgtaattattaatgaaatgttcactcctagtcccttatgaggcttagaatttcaaccacgtgtcaggtcagacagtattataaactgtactttgctgtctgagacagcacatttgtgaatgatgcttgctgcctgccattttcaacctattctctcttaagagtgctaggtaccaaattgtgaaagtttgttttcagttatattacttttgaggctggtgaaaaatttaaatgtaactttgtgggaacactgattcatatttagaaaatgtaaatgtctgtagcactttcttgcagttaatttgaaaactttggatgctgaaccttgtttgtcagtgatttagatgatttaaaaatgcatgtgtgatttgaattttataattgttttgacaagcataatttacttggacaacttcgtaggtagccttaacttctggccaagtttgttttttatataaatatatatacatatatacatattatgtatggttgtaaattcatacacttatcacatgaatgtgttactgtatacaaaactcttaatgctttattctcaaatgctgggttgaaaaatgttttgaaagccttttaaaatatatatctttataaagtaatattcaggatgatgataaaaattgtttatattgttatgataaaaatgacagtataatgttaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9748 -> Molecular function: GO:0004674 [protein serine/threonine kinase activity] evidence: IDA
GeneID:9748 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:9748 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: IDA
GeneID:9748 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:9748 -> Biological process: GO:0046777 [protein autophosphorylation] evidence: IDA
GeneID:9748 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:9748 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_055535 -> EC 2.7.11.1
by
@meso_cacase at
DBCLS
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