Home |
Help |
Advanced search
2025-05-11 18:59:30, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001252037 5217 bp mRNA linear PRI 16-JUN-2013
DEFINITION Homo sapiens RAB5B, member RAS oncogene family (RAB5B), transcript
variant 3, mRNA.
ACCESSION NM_001252037
VERSION NM_001252037.1 GI:354721178
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5217)
AUTHORS Tang,X.F., Zhang,Z., Hu,D.Y., Xu,A.E., Zhou,H.S., Sun,L.D., Gao,M.,
Gao,T.W., Gao,X.H., Chen,H.D., Xie,H.F., Tu,C.X., Hao,F., Wu,R.N.,
Zhang,F.R., Liang,L., Pu,X.M., Zhang,J.Z., Han,J.W., Pan,G.P.,
Wu,J.Q., Li,K., Su,M.W., Du,W.D., Zhang,W.J., Liu,J.J., Xiang,L.H.,
Yang,S., Zhou,Y.W. and Zhang,X.J.
TITLE Association analyses identify three susceptibility Loci for
vitiligo in the Chinese Han population
JOURNAL J. Invest. Dermatol. 133 (2), 403-410 (2013)
PUBMED 22951725
REFERENCE 2 (bases 1 to 5217)
AUTHORS Shi,Y., Zhao,H., Shi,Y., Cao,Y., Yang,D., Li,Z., Zhang,B.,
Liang,X., Li,T., Chen,J., Shen,J., Zhao,J., You,L., Gao,X., Zhu,D.,
Zhao,X., Yan,Y., Qin,Y., Li,W., Yan,J., Wang,Q., Zhao,J., Geng,L.,
Ma,J., Zhao,Y., He,G., Zhang,A., Zou,S., Yang,A., Liu,J., Li,W.,
Li,B., Wan,C., Qin,Y., Shi,J., Yang,J., Jiang,H., Xu,J.E., Qi,X.,
Sun,Y., Zhang,Y., Hao,C., Ju,X., Zhao,D., Ren,C.E., Li,X.,
Zhang,W., Zhang,Y., Zhang,J., Wu,D., Zhang,C., He,L. and Chen,Z.J.
TITLE Genome-wide association study identifies eight new risk loci for
polycystic ovary syndrome
JOURNAL Nat. Genet. 44 (9), 1020-1025 (2012)
PUBMED 22885925
REFERENCE 3 (bases 1 to 5217)
AUTHORS Chen,P.I., Kong,C., Su,X. and Stahl,P.D.
TITLE Rab5 isoforms differentially regulate the trafficking and
degradation of epidermal growth factor receptors
JOURNAL J. Biol. Chem. 284 (44), 30328-30338 (2009)
PUBMED 19723633
REMARK GeneRIF: suppression of Rab5A or 5B hampered the degradation of
EGFR
REFERENCE 4 (bases 1 to 5217)
AUTHORS Shin,N., Jeong,H., Kwon,J., Heo,H.Y., Kwon,J.J., Yun,H.J.,
Kim,C.H., Han,B.S., Tong,Y., Shen,J., Hatano,T., Hattori,N.,
Kim,K.S., Chang,S. and Seol,W.
TITLE LRRK2 regulates synaptic vesicle endocytosis
JOURNAL Exp. Cell Res. 314 (10), 2055-2065 (2008)
PUBMED 18445495
REMARK GeneRIF: Results suggest that LRRK2, in conjunction with its
interaction with Rab5b, plays an important role in synaptic
function by modulating the endocytosis of synaptic vesicles.
REFERENCE 5 (bases 1 to 5217)
AUTHORS Hakonarson,H., Qu,H.Q., Bradfield,J.P., Marchand,L., Kim,C.E.,
Glessner,J.T., Grabs,R., Casalunovo,T., Taback,S.P.,
Frackelton,E.C., Eckert,A.W., Annaiah,K., Lawson,M.L., Otieno,F.G.,
Santa,E., Shaner,J.L., Smith,R.M., Onyiah,C.C., Skraban,R.,
Chiavacci,R.M., Robinson,L.J., Stanley,C.A., Kirsch,S.E.,
Devoto,M., Monos,D.S., Grant,S.F. and Polychronakos,C.
TITLE A novel susceptibility locus for type 1 diabetes on Chr12q13
identified by a genome-wide association study
JOURNAL Diabetes 57 (4), 1143-1146 (2008)
PUBMED 18198356
REFERENCE 6 (bases 1 to 5217)
AUTHORS Callaghan,J., Nixon,S., Bucci,C., Toh,B.H. and Stenmark,H.
TITLE Direct interaction of EEA1 with Rab5b
JOURNAL Eur. J. Biochem. 265 (1), 361-366 (1999)
PUBMED 10491193
REFERENCE 7 (bases 1 to 5217)
AUTHORS Chiariello,M., Bruni,C.B. and Bucci,C.
TITLE The small GTPases Rab5a, Rab5b and Rab5c are differentially
phosphorylated in vitro
JOURNAL FEBS Lett. 453 (1-2), 20-24 (1999)
PUBMED 10403367
REFERENCE 8 (bases 1 to 5217)
AUTHORS Bao,S., Zhu,J. and Garvey,W.T.
TITLE Cloning of Rab GTPases expressed in human skeletal muscle: studies
in insulin-resistant subjects
JOURNAL Horm. Metab. Res. 30 (11), 656-662 (1998)
PUBMED 9918381
REFERENCE 9 (bases 1 to 5217)
AUTHORS Bucci,C., Lutcke,A., Steele-Mortimer,O., Olkkonen,V.M., Dupree,P.,
Chiariello,M., Bruni,C.B., Simons,K. and Zerial,M.
TITLE Co-operative regulation of endocytosis by three Rab5 isoforms
JOURNAL FEBS Lett. 366 (1), 65-71 (1995)
PUBMED 7789520
REFERENCE 10 (bases 1 to 5217)
AUTHORS Wilson,D.B. and Wilson,M.P.
TITLE Identification and subcellular localization of human rab5b, a new
member of the ras-related superfamily of GTPases
JOURNAL J. Clin. Invest. 89 (3), 996-1005 (1992)
PUBMED 1541686
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DA811144.1, DA401343.1, AK296517.1 and AC034102.32.
Transcript Variant: This variant (3) lacks an exon in the coding
region but maintains the reading frame, compared to variant 1. the
encoded isoform (2) is shorter than isoform 1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK296517.1, DA414526.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025086, ERS025091 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-24 DA811144.1 1-24
25-90 DA401343.1 2-67
91-1620 AK296517.1 1-1530
1621-5217 AC034102.32 164616-168212 c
FEATURES Location/Qualifiers
source 1..5217
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q13"
gene 1..5217
/gene="RAB5B"
/note="RAB5B, member RAS oncogene family"
/db_xref="GeneID:5869"
/db_xref="HGNC:9784"
/db_xref="MIM:179514"
exon 1..129
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 107
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:75639074"
exon 130..384
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 140
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:191222040"
variation 166
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:370178643"
variation 194
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199632895"
variation 197
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:202056188"
CDS 222..746
/gene="RAB5B"
/note="isoform 2 is encoded by transcript variant 3;
ras-related protein Rab-5B"
/codon_start=1
/product="ras-related protein Rab-5B isoform 2"
/protein_id="NP_001238966.1"
/db_xref="GI:354721179"
/db_xref="CCDS:CCDS58244.1"
/db_xref="GeneID:5869"
/db_xref="HGNC:9784"
/db_xref="MIM:179514"
/translation="
MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN
"
misc_feature 279..692
/gene="RAB5B"
/note="Ras-like protein; Provisional; Region: PTZ00369"
/db_xref="CDD:240385"
misc_feature 279..644
/gene="RAB5B"
/note="Rab-related GTPase family includes Rab5 and Rab22;
regulates early endosome fusion; Region: Rab5_related;
cd01860"
/db_xref="CDD:206653"
misc_feature 279..287
/gene="RAB5B"
/note="Rab subfamily motif 1 (RabSF1); other site"
/db_xref="CDD:206653"
misc_feature 300..323
/gene="RAB5B"
/note="G1 box; other site"
/db_xref="CDD:206653"
misc_feature order(306..326,354..359,372..377,453..455,585..593)
/gene="RAB5B"
/note="GTP/Mg2+ binding site [chemical binding]; other
site"
/db_xref="CDD:206653"
misc_feature order(324..359,369..374)
/gene="RAB5B"
/note="Rab subfamily motif 2 (RabSF2); other site"
/db_xref="CDD:206653"
misc_feature order(354..356,369..395)
/gene="RAB5B"
/note="Switch I region; other site"
/db_xref="CDD:206653"
misc_feature order(369..371,381..404,423..425,429..431)
/gene="RAB5B"
/note="putative GEF interaction site [polypeptide
binding]; other site"
/db_xref="CDD:206653"
misc_feature 375..377
/gene="RAB5B"
/note="G2 box; other site"
/db_xref="CDD:206653"
misc_feature order(378..383,387..389,441..446,465..467,471..473,
477..485)
/gene="RAB5B"
/note="putative GDI interaction site [polypeptide
binding]; other site"
/db_xref="CDD:206653"
misc_feature 378..392
/gene="RAB5B"
/note="Rab family motif 1 (RabF1); other site"
/db_xref="CDD:206653"
misc_feature order(384..392,396..398,462..464,483..488)
/gene="RAB5B"
/note="effector interaction site; other site"
/db_xref="CDD:206653"
misc_feature 429..443
/gene="RAB5B"
/note="Rab family motif 2 (RabF2); other site"
/db_xref="CDD:206653"
misc_feature 444..455
/gene="RAB5B"
/note="G3 box; other site"
/db_xref="CDD:206653"
misc_feature order(453..455,459..491)
/gene="RAB5B"
/note="Switch II region; other site"
/db_xref="CDD:206653"
misc_feature 462..479
/gene="RAB5B"
/note="Rab family motif 3 (RabF3); other site"
/db_xref="CDD:206653"
misc_feature 486..491
/gene="RAB5B"
/note="Rab family motif 4 (RabF4); other site"
/db_xref="CDD:206653"
misc_feature 513..530
/gene="RAB5B"
/note="Rab family motif 5 (RabF5); other site"
/db_xref="CDD:206653"
misc_feature 585..593
/gene="RAB5B"
/note="G5 box; other site"
/db_xref="CDD:206653"
misc_feature 633..641
/gene="RAB5B"
/note="Rab subfamily motif 4 (RabSF4); other site"
/db_xref="CDD:206653"
variation 250
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:151173738"
variation 299
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:200823103"
exon 385..536
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 404
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140257679"
variation 420
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:145456965"
variation 439
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200178158"
variation 510
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146500812"
variation 512
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:141101772"
exon 537..630
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 541
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:375947629"
variation 546
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:201470751"
variation 587
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:2292240"
variation 605
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199813423"
variation 606
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:371700996"
variation 608
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:144915792"
exon 631..5217
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 635
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:80286187"
variation 675
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:375538585"
variation 684
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:373383204"
variation 687
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:377046623"
variation 688
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201485586"
variation 689
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370187474"
variation 697
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:373831332"
variation 757
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:377488300"
variation 758
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:185392988"
variation 759
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:189968231"
variation 768
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:200616190"
variation 786
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:367803941"
variation 802
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:1050198"
variation 826
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:11550558"
variation 1007
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140669038"
variation 1037
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:12307159"
variation 1044
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:11611579"
variation 1045
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:374752542"
variation 1060
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:145665894"
variation 1094
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:3741500"
variation 1111
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:79669954"
variation 1174
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:1050200"
variation 1324
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:185729836"
variation 1335
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:188482287"
variation 1380
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:368421639"
variation 1403
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050201"
variation 1416
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:1050202"
variation 1417
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:1050203"
variation 1469..1470
/gene="RAB5B"
/replace=""
/replace="ct"
/db_xref="dbSNP:113186187"
variation 1496
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:148119300"
variation 1548
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:78564985"
variation 1559
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:79132668"
variation 1574
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050205"
variation 1576
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050206"
variation 1579
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:79333113"
variation 1649
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050209"
variation 1765
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:77597377"
variation 1785
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:180938710"
variation 1913
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370209440"
variation 2017
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:141821738"
variation 2158
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:150189189"
variation 2203
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:138736571"
STS 2262..2365
/gene="RAB5B"
/standard_name="RH44840"
/db_xref="UniSTS:89878"
variation 2361
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:7350566"
variation 2362
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:185902941"
variation 2426
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:143728615"
variation 2495
/gene="RAB5B"
/replace=""
/replace="t"
/db_xref="dbSNP:34151959"
STS 2570..2743
/gene="RAB5B"
/standard_name="RH98226"
/db_xref="UniSTS:92502"
variation 2598
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:192424702"
variation 2874
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373881222"
variation 2919..2920
/gene="RAB5B"
/replace=""
/replace="c"
/db_xref="dbSNP:371574885"
variation 2923
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:147229892"
variation 2958
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:1050231"
variation 2964
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:9323"
variation 2968
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:183872315"
variation 3057
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:187146028"
variation 3082
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:11673"
variation 3114
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:11550559"
variation 3318
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:191623441"
variation 3341
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:182724443"
variation 3467
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:112828948"
variation 3491
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:187091639"
variation 3541
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:191538953"
variation 3639
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:34962186"
variation 3643
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:77935289"
variation 3645
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:61937250"
variation 3669
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:140466173"
STS 3728..3816
/gene="RAB5B"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
variation 3760
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:142807841"
variation 3765
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:147371885"
variation 3804
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:144937485"
variation 3911
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:35105856"
variation 4043
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:705700"
variation 4107
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:150930056"
variation 4173
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:139483301"
variation 4214
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:143859506"
variation 4233
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:146878814"
variation 4264..4267
/gene="RAB5B"
/replace=""
/replace="tagt"
/db_xref="dbSNP:77509148"
variation 4275
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:182310393"
variation 4315
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:58717357"
variation 4372
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:11171718"
variation 4475..4476
/gene="RAB5B"
/replace=""
/replace="ct"
/db_xref="dbSNP:139044776"
variation 4492
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:191633678"
variation 4505
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:187526536"
variation 4506..4507
/gene="RAB5B"
/replace=""
/replace="at"
/db_xref="dbSNP:34061457"
variation 4507..4508
/gene="RAB5B"
/replace=""
/replace="atatatatatatatatatat"
/db_xref="dbSNP:72297536"
variation 4518..4537
/gene="RAB5B"
/replace="catatatatatatatatata"
/replace="tatatatatttttttttttt"
/db_xref="dbSNP:71457813"
variation 4518
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:705701"
variation 4519..4520
/gene="RAB5B"
/replace=""
/replace="at"
/db_xref="dbSNP:375903673"
variation 4535
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:374518488"
variation 4537
/gene="RAB5B"
/replace=""
/replace="a"
/db_xref="dbSNP:201079136"
variation 4537
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:4759233"
variation 4538..4539
/gene="RAB5B"
/replace=""
/replace="a"
/replace="atatatatatatatattttt"
/replace="atattttt"
/db_xref="dbSNP:376451058"
variation 4539..4540
/gene="RAB5B"
/replace=""
/replace="atatatatatatatattttt"
/replace="attttt"
/db_xref="dbSNP:63191860"
variation 4539
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:60028217"
variation 4547..4548
/gene="RAB5B"
/replace=""
/replace="ttttttt"
/db_xref="dbSNP:56291639"
variation 4727
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:11612906"
variation 4789
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:185511541"
variation 4937
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:78877196"
STS 5053..5155
/gene="RAB5B"
/standard_name="D11S2921"
/db_xref="UniSTS:152074"
variation 5073
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:190463944"
variation 5114
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:772920"
variation 5155
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:115698836"
variation 5180..5181
/gene="RAB5B"
/replace=""
/replace="t"
/db_xref="dbSNP:375369217"
variation 5181
/gene="RAB5B"
/replace=""
/replace="t"
/db_xref="dbSNP:143552015"
ORIGIN
aatcgagctattggctggagccccgccccagggcgaggaggagaaggaggggcaggagggtttggttgagctgcagctgtttgtctgttcgacacaggcttggggccgacgggggagacggagccccaggagtgttgaagcctggaaatcccctccccttccccctcccccctttacagtatccccctccctccaccctttcccattctgataatctggccatgactagcagaagcacagctaggcccaatgggcaaccccaggccagcaaaatttgccagttcaaattggtcctgctgggagaatctgcagtgggaaagtcaagcctggtattacgttttgtcaaagggcagttccatgagtaccaggagagcaccattggagcggccttcctcacccagtccgtttgtctagatgacacaacagtgaagtttgagatctgggacacagctgggcaggagcgatatcacagcttagcccccatgtactacaggggtgcccaagctgcaatcgtggtttacgacattactaatcaggaggcccaggcatatgcagatgacaacagcttattgttcatggagacttcagccaagacagctatgaacgtgaatgatctcttcctggcaatagctaagaagttgccaaagagtgaaccccagaatctgggaggtgcagcaggccgaagccggggtgtggatctccatgaacagtcccagcagaacaagagccagtgttgtagcaactgagggggtggctagcagcaaacaagtatggagctagcacaagagctaagaaataacctccatccctacccctcagcacacaacccctacggtaacagcacactgagccctggctcccaagggctgcctcctgacagctccgtcatggcactttttaacgcttcagcaacaaacaccaggcagctgttgccactggcctcctaccccctactctggggcttgggggtcaactccccccaggacttaccttccaaaacaaactttcttcactttgtattataggtacaagacagcgacttacgtatcttttctcctcctccctagtgttcctccccattttttcagaaaacacttctgactcctgtcccttccccttctgcttttggtcagtccctgttcttgagcctcttttctcctctccccaggatgcagaaagtggtgaacccaggaactgaggaaggaggtttccagttcatttacattaagggccctgggggagaataaagctcagagcaggagggagtaaggaaacatttcctttttgtttttatttggttggagtttctcatatttgaaaacattgcggtatccatgatttggccttgtggagggtgttcctaggtagaggtgagaatggggaggcaagatctcaggcaccaggcaggaggtgccttgtaagctaactgggcggaggtggaggtgcagtgtcaactgtggctctgtaactcttcaaaggcccagtttcccctcacgcagcctcttaggtagcgtttcccctaatcgtgggggttggaccccagagtcttccaaagaattttcactggttgcctgcatctttggctctgctgtgatctgattggaggagggacagtttctggtacccatcctctgatttatacatatgcattttttcccctctggcctttagatggcctcagccccagccaccatatacccctgcagtttgcactttaattgatggtagttcagttggggtacttgttttatggaagttttgattgatttacttgccctcccaccttctttttaattcaatgaaatctgaggttaatgcgaggttcgaggagaggttatagataaaactaccagtggcagctactcaagtcctatctccactgttagcttcctccaactctaattattaacctatattcttgccaagctaactattgactataggtttgcctttcctggagaattaattgagcaattgaggagtgtctcaggatagcacaggccaaggtaggggagtaaaaaggaggtcaggcaaaagggaggagttttctgtcctttcccaggtttcacactcaatttgatatccattaccatgtcttttctacttccttgtaaataggtatgatctttattcccactgtacagtctgttctatcctctgcctcccatcaggccctgtttctttgttcctttgttaatatcttgaatttagtccctccatccttaatccccccatccctccccatcatgcaaccagtggtttaatccatgtaccaataggggctagtaccacagaggcctcctgtggtgccctcgtatcataccacctgttcctgtggagagggaatgaccggcactgaaggtaccttacaactggctcatattatcagaggaccttggtcctttctaaatctctagtctctcttcatatccttcatcaggtgttttaagatgtctctgagaagccatcaaggcaaaagagaactttaagttccttgttccagcccggagttttgggaaagaaagaaaggaaaggtcacagtgacctaggattggaaccttcctgcccttttggcttgcagactgccttctatcccagaacagctgagaaatctatgaagctgagattctgaaggacccagcttaggttcttccacttaggcctcaattcccttccttttccaggggcagccttagttcccatggccctgaaacacacacatttcccccttcctttcccagaagccactggccccccatagcacccagtgcatcctttttacaagtggaagaactaggatggctttccaaagtcttctagaaatgaagttctttctctgtgcagctttcccccttggagcaggagtgaagatgtttcattatcttgggcctgggaaaccacttccccaggcttctccctccccccacccccataggaacaggatttggccttagcttctgggcctatcggctgccttccctctacttcctaccacctcttctgccttcctttgagctctgttgggcttggggatcttagttttcttttgtttatttcccagctcatttttttcttctggtcagtttttttaagggggggtgttgtggttttttgtttttgttttgcttctgagaaagcatttgcctttcttcctctcccaacataacaatcgtggtaacagaatgcgactgctgatttaccgatgtatttaatgtaagtaaaaaaaggaaaaaaagaaaagggcattggagtgttgcttttttttattttattgttattattattattatttttgctatttgtcaggtactaggaatttggaagaaaggatacccagtaatgttctactgaatcagaaacacacctttccctgcatcttgatacatctttattccctttaatcttttcttaaacatctagtttagaaaatagcccttctattgctatttaatcacccctcttctaaggccactagattgttcatcaaatcaaaccctattatatctttttaggccctcttaacagaatgtatatgtgtagggtatggtctgtggatctttgggcccactgatcagattagagagaggggtgctatttgaagtagtatacaaaaatgtatgtgcatatttctttttttttttttaattgagacggagtctctgtcgctagcctggagtacagtggcacgatcttggctcacagcaatctccgcctcctgagttcaagtgattctcctgcctcagcctcctgagtagctaggattacaggcacgcaccaacacacccagctaatttttgtatttttagtagagacggggtttcaccatgttggtcaggctggtcttgaactcctgacctcgtgatccacccaccttggcctcccaaagtgctgggattacgggcgtgagccactgcgcccggccgtatgtgcatatttctaggatccatttctatatgtttctcaaaggggtccatgacccaaaggttgaaaaacatcactgagttagttttcttgtagcttccacctcaacgggaaaatttcctctggatctgctcttgactcctagtgtacttcaaacccttcagtccaccacagtctaaaggtcgagggaagggaaatgaaataggattatgtgtggttgcagtaggctttaaattccaaagaatctgaaggtggataggaaagaggactggtgccagacaaatctgacattctaggcctgtctctgtcaacttaaccagctgtggccttgatcaagttagttagtgccttccgcctcgtttcttcatctgtaaagtaaaagctgaagattaaggtcaattatgtaaagtatgtgtgtcacacaaaagtagatgacactattaggaaggaggcttttagatagtccctaactgacttctctgtatcttcctttggctgagacttttttttttttaggttgaagctcgctttctctctctctccctctttctccctctctctctctctctcactctctctctctccatatatatatacatatatatatatatatatattttttttttaacaactggtaggataggttgggcattagccttcttcagtgatttgattgtatacagattgaaatcctttccatttccaaacacttaagagccaaagccaacttgccaacttttcactgtcggttcccttaccttatatctcttggtaataccccccacccccgttccctgattcctggtaaaagctctagttggagagccgaaaggaaaggaaatgatctttcaaaattaaaggtgaacaccttcacttaaactgattaaaattgcagctccaccgtccggcctctagagggcagtgtatggatacatttgtccagattgggggactaggtttgataaattttgtcctgcatcaaatgacaaaagggtaataggaaatgtattatatttatgccccttactttgagataagagactacaaccttcatacttcggggtgttaagctgccattgctcttgttaaggggcagtttgttttttaagagatggggtcttgctctgttgtccaggctggagtgcagtgccgcgatcttggctcagtgcaacctcgaactcctgggcttaagcgatcctcccgcctcagcctcccgagtactgggactacaggcgtgtgccaccaaggggcgattattattttttttttctacgcaaaataaaagacggctattca
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5869 -> Molecular function: GO:0003924 [GTPase activity] evidence: TAS
GeneID:5869 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:5869 -> Molecular function: GO:0005525 [GTP binding] evidence: IEA
GeneID:5869 -> Molecular function: GO:0019003 [GDP binding] evidence: IDA
GeneID:5869 -> Molecular function: GO:0030742 [GTP-dependent protein binding] evidence: IDA
GeneID:5869 -> Biological process: GO:0006184 [GTP catabolic process] evidence: TAS
GeneID:5869 -> Biological process: GO:0007032 [endosome organization] evidence: IEA
GeneID:5869 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: IEA
GeneID:5869 -> Biological process: GO:0015031 [protein transport] evidence: IEA
GeneID:5869 -> Biological process: GO:0030100 [regulation of endocytosis] evidence: IEA
GeneID:5869 -> Cellular component: GO:0005622 [intracellular] evidence: IDA
GeneID:5869 -> Cellular component: GO:0005768 [endosome] evidence: IDA
GeneID:5869 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA
GeneID:5869 -> Cellular component: GO:0016020 [membrane] evidence: TAS
GeneID:5869 -> Cellular component: GO:0030139 [endocytic vesicle] evidence: IEA
GeneID:5869 -> Cellular component: GO:0031901 [early endosome membrane] evidence: IEA
GeneID:5869 -> Cellular component: GO:0042470 [melanosome] evidence: IEA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.