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2025-05-11 18:01:19, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001252036 5299 bp mRNA linear PRI 16-JUN-2013
DEFINITION Homo sapiens RAB5B, member RAS oncogene family (RAB5B), transcript
variant 2, mRNA.
ACCESSION NM_001252036
VERSION NM_001252036.1 GI:354725901
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5299)
AUTHORS Tang,X.F., Zhang,Z., Hu,D.Y., Xu,A.E., Zhou,H.S., Sun,L.D., Gao,M.,
Gao,T.W., Gao,X.H., Chen,H.D., Xie,H.F., Tu,C.X., Hao,F., Wu,R.N.,
Zhang,F.R., Liang,L., Pu,X.M., Zhang,J.Z., Han,J.W., Pan,G.P.,
Wu,J.Q., Li,K., Su,M.W., Du,W.D., Zhang,W.J., Liu,J.J., Xiang,L.H.,
Yang,S., Zhou,Y.W. and Zhang,X.J.
TITLE Association analyses identify three susceptibility Loci for
vitiligo in the Chinese Han population
JOURNAL J. Invest. Dermatol. 133 (2), 403-410 (2013)
PUBMED 22951725
REFERENCE 2 (bases 1 to 5299)
AUTHORS Shi,Y., Zhao,H., Shi,Y., Cao,Y., Yang,D., Li,Z., Zhang,B.,
Liang,X., Li,T., Chen,J., Shen,J., Zhao,J., You,L., Gao,X., Zhu,D.,
Zhao,X., Yan,Y., Qin,Y., Li,W., Yan,J., Wang,Q., Zhao,J., Geng,L.,
Ma,J., Zhao,Y., He,G., Zhang,A., Zou,S., Yang,A., Liu,J., Li,W.,
Li,B., Wan,C., Qin,Y., Shi,J., Yang,J., Jiang,H., Xu,J.E., Qi,X.,
Sun,Y., Zhang,Y., Hao,C., Ju,X., Zhao,D., Ren,C.E., Li,X.,
Zhang,W., Zhang,Y., Zhang,J., Wu,D., Zhang,C., He,L. and Chen,Z.J.
TITLE Genome-wide association study identifies eight new risk loci for
polycystic ovary syndrome
JOURNAL Nat. Genet. 44 (9), 1020-1025 (2012)
PUBMED 22885925
REFERENCE 3 (bases 1 to 5299)
AUTHORS Chen,P.I., Kong,C., Su,X. and Stahl,P.D.
TITLE Rab5 isoforms differentially regulate the trafficking and
degradation of epidermal growth factor receptors
JOURNAL J. Biol. Chem. 284 (44), 30328-30338 (2009)
PUBMED 19723633
REMARK GeneRIF: suppression of Rab5A or 5B hampered the degradation of
EGFR
REFERENCE 4 (bases 1 to 5299)
AUTHORS Shin,N., Jeong,H., Kwon,J., Heo,H.Y., Kwon,J.J., Yun,H.J.,
Kim,C.H., Han,B.S., Tong,Y., Shen,J., Hatano,T., Hattori,N.,
Kim,K.S., Chang,S. and Seol,W.
TITLE LRRK2 regulates synaptic vesicle endocytosis
JOURNAL Exp. Cell Res. 314 (10), 2055-2065 (2008)
PUBMED 18445495
REMARK GeneRIF: Results suggest that LRRK2, in conjunction with its
interaction with Rab5b, plays an important role in synaptic
function by modulating the endocytosis of synaptic vesicles.
REFERENCE 5 (bases 1 to 5299)
AUTHORS Hakonarson,H., Qu,H.Q., Bradfield,J.P., Marchand,L., Kim,C.E.,
Glessner,J.T., Grabs,R., Casalunovo,T., Taback,S.P.,
Frackelton,E.C., Eckert,A.W., Annaiah,K., Lawson,M.L., Otieno,F.G.,
Santa,E., Shaner,J.L., Smith,R.M., Onyiah,C.C., Skraban,R.,
Chiavacci,R.M., Robinson,L.J., Stanley,C.A., Kirsch,S.E.,
Devoto,M., Monos,D.S., Grant,S.F. and Polychronakos,C.
TITLE A novel susceptibility locus for type 1 diabetes on Chr12q13
identified by a genome-wide association study
JOURNAL Diabetes 57 (4), 1143-1146 (2008)
PUBMED 18198356
REFERENCE 6 (bases 1 to 5299)
AUTHORS Callaghan,J., Nixon,S., Bucci,C., Toh,B.H. and Stenmark,H.
TITLE Direct interaction of EEA1 with Rab5b
JOURNAL Eur. J. Biochem. 265 (1), 361-366 (1999)
PUBMED 10491193
REFERENCE 7 (bases 1 to 5299)
AUTHORS Chiariello,M., Bruni,C.B. and Bucci,C.
TITLE The small GTPases Rab5a, Rab5b and Rab5c are differentially
phosphorylated in vitro
JOURNAL FEBS Lett. 453 (1-2), 20-24 (1999)
PUBMED 10403367
REFERENCE 8 (bases 1 to 5299)
AUTHORS Bao,S., Zhu,J. and Garvey,W.T.
TITLE Cloning of Rab GTPases expressed in human skeletal muscle: studies
in insulin-resistant subjects
JOURNAL Horm. Metab. Res. 30 (11), 656-662 (1998)
PUBMED 9918381
REFERENCE 9 (bases 1 to 5299)
AUTHORS Bucci,C., Lutcke,A., Steele-Mortimer,O., Olkkonen,V.M., Dupree,P.,
Chiariello,M., Bruni,C.B., Simons,K. and Zerial,M.
TITLE Co-operative regulation of endocytosis by three Rab5 isoforms
JOURNAL FEBS Lett. 366 (1), 65-71 (1995)
PUBMED 7789520
REFERENCE 10 (bases 1 to 5299)
AUTHORS Wilson,D.B. and Wilson,M.P.
TITLE Identification and subcellular localization of human rab5b, a new
member of the ras-related superfamily of GTPases
JOURNAL J. Clin. Invest. 89 (3), 996-1005 (1992)
PUBMED 1541686
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AC034102.32 and BC032740.1.
Transcript Variant: This variant (2) differs in the 5' UTR compared
to variant 1. Variants 1 and 2 encode the same isoform (1).
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC032740.1, BM472546.1 [ECO:0000332]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-63 AC034102.32 187324-187386 c
64-3317 BC032740.1 12-3265
3318-5299 AC034102.32 164616-166597 c
FEATURES Location/Qualifiers
source 1..5299
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q13"
gene 1..5299
/gene="RAB5B"
/note="RAB5B, member RAS oncogene family"
/db_xref="GeneID:5869"
/db_xref="HGNC:9784"
/db_xref="MIM:179514"
exon 1..88
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 16
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:77322402"
variation 38
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:77494178"
misc_feature 73..75
/gene="RAB5B"
/note="upstream in-frame stop codon"
exon 89..343
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 99
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:191222040"
variation 125
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:370178643"
variation 153
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199632895"
variation 156
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:202056188"
CDS 181..828
/gene="RAB5B"
/note="isoform 1 is encoded by transcript variant 2;
ras-related protein Rab-5B"
/codon_start=1
/product="ras-related protein Rab-5B isoform 1"
/protein_id="NP_001238965.1"
/db_xref="GI:354725902"
/db_xref="CCDS:CCDS8900.1"
/db_xref="GeneID:5869"
/db_xref="HGNC:9784"
/db_xref="MIM:179514"
/translation="
MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN
"
misc_feature 238..774
/gene="RAB5B"
/note="Ras-like protein; Provisional; Region: PTZ00369"
/db_xref="CDD:240385"
misc_feature 238..726
/gene="RAB5B"
/note="Rab-related GTPase family includes Rab5 and Rab22;
regulates early endosome fusion; Region: Rab5_related;
cd01860"
/db_xref="CDD:206653"
misc_feature 238..246
/gene="RAB5B"
/note="Rab subfamily motif 1 (RabSF1); other site"
/db_xref="CDD:206653"
misc_feature 259..282
/gene="RAB5B"
/note="G1 box; other site"
/db_xref="CDD:206653"
misc_feature order(265..285,313..318,331..336,412..414,577..582,
586..588,667..675)
/gene="RAB5B"
/note="GTP/Mg2+ binding site [chemical binding]; other
site"
/db_xref="CDD:206653"
misc_feature order(283..318,328..333)
/gene="RAB5B"
/note="Rab subfamily motif 2 (RabSF2); other site"
/db_xref="CDD:206653"
misc_feature order(313..315,328..354)
/gene="RAB5B"
/note="Switch I region; other site"
/db_xref="CDD:206653"
misc_feature 325..351
/gene="RAB5B"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P61020.1);
Region: Effector region (Potential)"
misc_feature order(328..330,340..363,382..384,388..390)
/gene="RAB5B"
/note="putative GEF interaction site [polypeptide
binding]; other site"
/db_xref="CDD:206653"
misc_feature 334..336
/gene="RAB5B"
/note="G2 box; other site"
/db_xref="CDD:206653"
misc_feature order(337..342,346..348,400..405,424..426,430..432,
436..444)
/gene="RAB5B"
/note="putative GDI interaction site [polypeptide
binding]; other site"
/db_xref="CDD:206653"
misc_feature 337..351
/gene="RAB5B"
/note="Rab family motif 1 (RabF1); other site"
/db_xref="CDD:206653"
misc_feature order(343..351,355..357,421..423,442..447)
/gene="RAB5B"
/note="effector interaction site; other site"
/db_xref="CDD:206653"
misc_feature 388..402
/gene="RAB5B"
/note="Rab family motif 2 (RabF2); other site"
/db_xref="CDD:206653"
misc_feature 403..414
/gene="RAB5B"
/note="G3 box; other site"
/db_xref="CDD:206653"
misc_feature order(412..414,418..450)
/gene="RAB5B"
/note="Switch II region; other site"
/db_xref="CDD:206653"
misc_feature 421..438
/gene="RAB5B"
/note="Rab family motif 3 (RabF3); other site"
/db_xref="CDD:206653"
misc_feature 445..450
/gene="RAB5B"
/note="Rab family motif 4 (RabF4); other site"
/db_xref="CDD:206653"
misc_feature 472..489
/gene="RAB5B"
/note="Rab family motif 5 (RabF5); other site"
/db_xref="CDD:206653"
misc_feature 553..570
/gene="RAB5B"
/note="Rab subfamily motif 3 (RabSF3); other site"
/db_xref="CDD:206653"
misc_feature 577..588
/gene="RAB5B"
/note="G4 box; other site"
/db_xref="CDD:206653"
misc_feature 667..675
/gene="RAB5B"
/note="G5 box; other site"
/db_xref="CDD:206653"
misc_feature 715..723
/gene="RAB5B"
/note="Rab subfamily motif 4 (RabSF4); other site"
/db_xref="CDD:206653"
variation 209
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:151173738"
variation 258
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:200823103"
exon 344..495
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 363
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140257679"
variation 379
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:145456965"
variation 398
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:200178158"
variation 469
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:146500812"
variation 471
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:141101772"
exon 496..618
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 519
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201304194"
variation 559
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:140556276"
exon 619..712
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 623
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:375947629"
variation 628
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:201470751"
variation 669
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:2292240"
variation 687
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:199813423"
variation 688
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:371700996"
variation 690
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:144915792"
exon 713..5299
/gene="RAB5B"
/inference="alignment:Splign:1.39.8"
variation 717
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:80286187"
variation 757
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:375538585"
variation 766
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:373383204"
variation 769
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:377046623"
variation 770
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:201485586"
variation 771
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370187474"
variation 779
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:373831332"
variation 839
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:377488300"
variation 840
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:185392988"
variation 841
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:189968231"
variation 850
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:200616190"
variation 868
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:367803941"
variation 884
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:1050198"
variation 908
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:11550558"
variation 1089
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:140669038"
variation 1119
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:12307159"
variation 1126
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:11611579"
variation 1127
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:374752542"
variation 1142
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:145665894"
variation 1176
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:3741500"
variation 1193
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:79669954"
variation 1256
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:1050200"
variation 1406
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:185729836"
variation 1417
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:188482287"
variation 1462
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:368421639"
variation 1485
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050201"
variation 1498
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:1050202"
variation 1499
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:1050203"
variation 1551..1552
/gene="RAB5B"
/replace=""
/replace="ct"
/db_xref="dbSNP:113186187"
variation 1578
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:148119300"
variation 1630
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:78564985"
variation 1641
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:79132668"
variation 1656
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050205"
variation 1658
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050206"
variation 1661
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:79333113"
variation 1731
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:1050209"
variation 1847
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:77597377"
variation 1867
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:180938710"
variation 1995
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:370209440"
variation 2099
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:141821738"
variation 2240
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:150189189"
variation 2285
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:138736571"
STS 2344..2447
/gene="RAB5B"
/standard_name="RH44840"
/db_xref="UniSTS:89878"
variation 2443
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:7350566"
variation 2444
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:185902941"
variation 2508
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:143728615"
variation 2577
/gene="RAB5B"
/replace=""
/replace="t"
/db_xref="dbSNP:34151959"
STS 2652..2825
/gene="RAB5B"
/standard_name="RH98226"
/db_xref="UniSTS:92502"
variation 2680
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:192424702"
variation 2956
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:373881222"
variation 3001..3002
/gene="RAB5B"
/replace=""
/replace="c"
/db_xref="dbSNP:371574885"
variation 3005
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:147229892"
variation 3040
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:1050231"
variation 3046
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:9323"
variation 3050
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:183872315"
variation 3139
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:187146028"
variation 3164
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:11673"
variation 3196
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:11550559"
variation 3400
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:191623441"
variation 3423
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:182724443"
variation 3549
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:112828948"
variation 3573
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:187091639"
variation 3623
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:191538953"
variation 3721
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:34962186"
variation 3725
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:77935289"
variation 3727
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:61937250"
variation 3751
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:140466173"
STS 3810..3898
/gene="RAB5B"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
variation 3842
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:142807841"
variation 3847
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:147371885"
variation 3886
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:144937485"
variation 3993
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:35105856"
variation 4125
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:705700"
variation 4189
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:150930056"
variation 4255
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:139483301"
variation 4296
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:143859506"
variation 4315
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:146878814"
variation 4346..4349
/gene="RAB5B"
/replace=""
/replace="tagt"
/db_xref="dbSNP:77509148"
variation 4357
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:182310393"
variation 4397
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:58717357"
variation 4454
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:11171718"
variation 4557..4558
/gene="RAB5B"
/replace=""
/replace="ct"
/db_xref="dbSNP:139044776"
variation 4574
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:191633678"
variation 4587
/gene="RAB5B"
/replace="a"
/replace="c"
/db_xref="dbSNP:187526536"
variation 4588..4589
/gene="RAB5B"
/replace=""
/replace="at"
/db_xref="dbSNP:34061457"
variation 4589..4590
/gene="RAB5B"
/replace=""
/replace="atatatatatatatatatat"
/db_xref="dbSNP:72297536"
variation 4600..4619
/gene="RAB5B"
/replace="catatatatatatatatata"
/replace="tatatatatttttttttttt"
/db_xref="dbSNP:71457813"
variation 4600
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:705701"
variation 4601..4602
/gene="RAB5B"
/replace=""
/replace="at"
/db_xref="dbSNP:375903673"
variation 4617
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:374518488"
variation 4619
/gene="RAB5B"
/replace=""
/replace="a"
/db_xref="dbSNP:201079136"
variation 4619
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:4759233"
variation 4620..4621
/gene="RAB5B"
/replace=""
/replace="a"
/replace="atatatatatatatattttt"
/replace="atattttt"
/db_xref="dbSNP:376451058"
variation 4621..4622
/gene="RAB5B"
/replace=""
/replace="atatatatatatatattttt"
/replace="attttt"
/db_xref="dbSNP:63191860"
variation 4621
/gene="RAB5B"
/replace="a"
/replace="t"
/db_xref="dbSNP:60028217"
variation 4629..4630
/gene="RAB5B"
/replace=""
/replace="ttttttt"
/db_xref="dbSNP:56291639"
variation 4809
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:11612906"
variation 4871
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:185511541"
variation 5019
/gene="RAB5B"
/replace="g"
/replace="t"
/db_xref="dbSNP:78877196"
STS 5135..5237
/gene="RAB5B"
/standard_name="D11S2921"
/db_xref="UniSTS:152074"
variation 5155
/gene="RAB5B"
/replace="a"
/replace="g"
/db_xref="dbSNP:190463944"
variation 5196
/gene="RAB5B"
/replace="c"
/replace="g"
/db_xref="dbSNP:772920"
variation 5237
/gene="RAB5B"
/replace="c"
/replace="t"
/db_xref="dbSNP:115698836"
variation 5262..5263
/gene="RAB5B"
/replace=""
/replace="t"
/db_xref="dbSNP:375369217"
variation 5263
/gene="RAB5B"
/replace=""
/replace="t"
/db_xref="dbSNP:143552015"
ORIGIN
gctcgtacttgttggtgacagcgcccaaagagactcgcctttctccagaggattggtggatgagtgcacatatagcccaccctcgaaggagtgttgaagcctggaaatcccctccccttccccctcccccctttacagtatccccctccctccaccctttcccattctgataatctggccatgactagcagaagcacagctaggcccaatgggcaaccccaggccagcaaaatttgccagttcaaattggtcctgctgggagaatctgcagtgggaaagtcaagcctggtattacgttttgtcaaagggcagttccatgagtaccaggagagcaccattggagcggccttcctcacccagtccgtttgtctagatgacacaacagtgaagtttgagatctgggacacagctgggcaggagcgatatcacagcttagcccccatgtactacaggggtgcccaagctgcaatcgtggtttacgacattactaatcaggaaacctttgcccgagcaaagacatgggtgaaggaactacagcgacaggccagtcctagcatcgttattgccctggcagggaacaaagctgacctggccaacaaacgtatggtggagtatgaagaggcccaggcatatgcagatgacaacagcttattgttcatggagacttcagccaagacagctatgaacgtgaatgatctcttcctggcaatagctaagaagttgccaaagagtgaaccccagaatctgggaggtgcagcaggccgaagccggggtgtggatctccatgaacagtcccagcagaacaagagccagtgttgtagcaactgagggggtggctagcagcaaacaagtatggagctagcacaagagctaagaaataacctccatccctacccctcagcacacaacccctacggtaacagcacactgagccctggctcccaagggctgcctcctgacagctccgtcatggcactttttaacgcttcagcaacaaacaccaggcagctgttgccactggcctcctaccccctactctggggcttgggggtcaactccccccaggacttaccttccaaaacaaactttcttcactttgtattataggtacaagacagcgacttacgtatcttttctcctcctccctagtgttcctccccattttttcagaaaacacttctgactcctgtcccttccccttctgcttttggtcagtccctgttcttgagcctcttttctcctctccccaggatgcagaaagtggtgaacccaggaactgaggaaggaggtttccagttcatttacattaagggccctgggggagaataaagctcagagcaggagggagtaaggaaacatttcctttttgtttttatttggttggagtttctcatatttgaaaacattgcggtatccatgatttggccttgtggagggtgttcctaggtagaggtgagaatggggaggcaagatctcaggcaccaggcaggaggtgccttgtaagctaactgggcggaggtggaggtgcagtgtcaactgtggctctgtaactcttcaaaggcccagtttcccctcacgcagcctcttaggtagcgtttcccctaatcgtgggggttggaccccagagtcttccaaagaattttcactggttgcctgcatctttggctctgctgtgatctgattggaggagggacagtttctggtacccatcctctgatttatacatatgcattttttcccctctggcctttagatggcctcagccccagccaccatatacccctgcagtttgcactttaattgatggtagttcagttggggtacttgttttatggaagttttgattgatttacttgccctcccaccttctttttaattcaatgaaatctgaggttaatgcgaggttcgaggagaggttatagataaaactaccagtggcagctactcaagtcctatctccactgttagcttcctccaactctaattattaacctatattcttgccaagctaactattgactataggtttgcctttcctggagaattaattgagcaattgaggagtgtctcaggatagcacaggccaaggtaggggagtaaaaaggaggtcaggcaaaagggaggagttttctgtcctttcccaggtttcacactcaatttgatatccattaccatgtcttttctacttccttgtaaataggtatgatctttattcccactgtacagtctgttctatcctctgcctcccatcaggccctgtttctttgttcctttgttaatatcttgaatttagtccctccatccttaatccccccatccctccccatcatgcaaccagtggtttaatccatgtaccaataggggctagtaccacagaggcctcctgtggtgccctcgtatcataccacctgttcctgtggagagggaatgaccggcactgaaggtaccttacaactggctcatattatcagaggaccttggtcctttctaaatctctagtctctcttcatatccttcatcaggtgttttaagatgtctctgagaagccatcaaggcaaaagagaactttaagttccttgttccagcccggagttttgggaaagaaagaaaggaaaggtcacagtgacctaggattggaaccttcctgcccttttggcttgcagactgccttctatcccagaacagctgagaaatctatgaagctgagattctgaaggacccagcttaggttcttccacttaggcctcaattcccttccttttccaggggcagccttagttcccatggccctgaaacacacacatttcccccttcctttcccagaagccactggccccccatagcacccagtgcatcctttttacaagtggaagaactaggatggctttccaaagtcttctagaaatgaagttctttctctgtgcagctttcccccttggagcaggagtgaagatgtttcattatcttgggcctgggaaaccacttccccaggcttctccctccccccacccccataggaacaggatttggccttagcttctgggcctatcggctgccttccctctacttcctaccacctcttctgccttcctttgagctctgttgggcttggggatcttagttttcttttgtttatttcccagctcatttttttcttctggtcagtttttttaagggggggtgttgtggttttttgtttttgttttgcttctgagaaagcatttgcctttcttcctctcccaacataacaatcgtggtaacagaatgcgactgctgatttaccgatgtatttaatgtaagtaaaaaaaggaaaaaaagaaaagggcattggagtgttgcttttttttattttattgttattattattattatttttgctatttgtcaggtactaggaatttggaagaaaggatacccagtaatgttctactgaatcagaaacacacctttccctgcatcttgatacatctttattccctttaatcttttcttaaacatctagtttagaaaatagcccttctattgctatttaatcacccctcttctaaggccactagattgttcatcaaatcaaaccctattatatctttttaggccctcttaacagaatgtatatgtgtagggtatggtctgtggatctttgggcccactgatcagattagagagaggggtgctatttgaagtagtatacaaaaatgtatgtgcatatttctttttttttttttaattgagacggagtctctgtcgctagcctggagtacagtggcacgatcttggctcacagcaatctccgcctcctgagttcaagtgattctcctgcctcagcctcctgagtagctaggattacaggcacgcaccaacacacccagctaatttttgtatttttagtagagacggggtttcaccatgttggtcaggctggtcttgaactcctgacctcgtgatccacccaccttggcctcccaaagtgctgggattacgggcgtgagccactgcgcccggccgtatgtgcatatttctaggatccatttctatatgtttctcaaaggggtccatgacccaaaggttgaaaaacatcactgagttagttttcttgtagcttccacctcaacgggaaaatttcctctggatctgctcttgactcctagtgtacttcaaacccttcagtccaccacagtctaaaggtcgagggaagggaaatgaaataggattatgtgtggttgcagtaggctttaaattccaaagaatctgaaggtggataggaaagaggactggtgccagacaaatctgacattctaggcctgtctctgtcaacttaaccagctgtggccttgatcaagttagttagtgccttccgcctcgtttcttcatctgtaaagtaaaagctgaagattaaggtcaattatgtaaagtatgtgtgtcacacaaaagtagatgacactattaggaaggaggcttttagatagtccctaactgacttctctgtatcttcctttggctgagacttttttttttttaggttgaagctcgctttctctctctctccctctttctccctctctctctctctctcactctctctctctccatatatatatacatatatatatatatatatattttttttttaacaactggtaggataggttgggcattagccttcttcagtgatttgattgtatacagattgaaatcctttccatttccaaacacttaagagccaaagccaacttgccaacttttcactgtcggttcccttaccttatatctcttggtaataccccccacccccgttccctgattcctggtaaaagctctagttggagagccgaaaggaaaggaaatgatctttcaaaattaaaggtgaacaccttcacttaaactgattaaaattgcagctccaccgtccggcctctagagggcagtgtatggatacatttgtccagattgggggactaggtttgataaattttgtcctgcatcaaatgacaaaagggtaataggaaatgtattatatttatgccccttactttgagataagagactacaaccttcatacttcggggtgttaagctgccattgctcttgttaaggggcagtttgttttttaagagatggggtcttgctctgttgtccaggctggagtgcagtgccgcgatcttggctcagtgcaacctcgaactcctgggcttaagcgatcctcccgcctcagcctcccgagtactgggactacaggcgtgtgccaccaaggggcgattattattttttttttctacgcaaaataaaagacggctattca
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5869 -> Molecular function: GO:0003924 [GTPase activity] evidence: TAS
GeneID:5869 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:5869 -> Molecular function: GO:0005525 [GTP binding] evidence: IEA
GeneID:5869 -> Molecular function: GO:0019003 [GDP binding] evidence: IDA
GeneID:5869 -> Molecular function: GO:0030742 [GTP-dependent protein binding] evidence: IDA
GeneID:5869 -> Biological process: GO:0006184 [GTP catabolic process] evidence: TAS
GeneID:5869 -> Biological process: GO:0007032 [endosome organization] evidence: IEA
GeneID:5869 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: IEA
GeneID:5869 -> Biological process: GO:0015031 [protein transport] evidence: IEA
GeneID:5869 -> Biological process: GO:0030100 [regulation of endocytosis] evidence: IEA
GeneID:5869 -> Cellular component: GO:0005622 [intracellular] evidence: IDA
GeneID:5869 -> Cellular component: GO:0005768 [endosome] evidence: IDA
GeneID:5869 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA
GeneID:5869 -> Cellular component: GO:0016020 [membrane] evidence: TAS
GeneID:5869 -> Cellular component: GO:0030139 [endocytic vesicle] evidence: IEA
GeneID:5869 -> Cellular component: GO:0031901 [early endosome membrane] evidence: IEA
GeneID:5869 -> Cellular component: GO:0042470 [melanosome] evidence: IEA
by
@meso_cacase at
DBCLS
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