LOCUS       NM_024337               1858 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens iroquois homeobox 1 (IRX1), mRNA.
ACCESSION   NM_024337 XM_098320
VERSION     NM_024337.3  GI:51479176
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1858)
  AUTHORS   Ovsyannikova,I.G., Kennedy,R.B., O'Byrne,M., Jacobson,R.M.,
            Pankratz,V.S. and Poland,G.A.
  TITLE     Genome-wide association study of antibody response to smallpox
            vaccine
  JOURNAL   Vaccine 30 (28), 4182-4189 (2012)
   PUBMED   22542470
REFERENCE   2  (bases 1 to 1858)
  AUTHORS   Jiang,J., Liu,W., Guo,X., Zhang,R., Zhi,Q., Ji,J., Zhang,J.,
            Chen,X., Li,J., Zhang,J., Gu,Q., Liu,B., Zhu,Z. and Yu,Y.
  TITLE     IRX1 influences peritoneal spreading and metastasis via inhibiting
            BDKRB2-dependent neovascularization on gastric cancer
  JOURNAL   Oncogene 30 (44), 4498-4508 (2011)
   PUBMED   21602894
  REMARK    GeneRIF: enforcing IRX1 expression effectively suppresses
            peritoneal spreading and pulmonary metastasis via anti-angiogenesis
            and anti-VM mechanisms, in addition to previously found cell growth
            and invasion.
REFERENCE   3  (bases 1 to 1858)
  AUTHORS   Guo,X.B., Guo,L., Zhi,Q.M., Ji,J., Jiang,J.L., Zhang,R.J.,
            Zhang,J.N., Zhang,J., Chen,X.H., Cai,Q., Li,J.F., Yan,M., Gu,Q.L.,
            Liu,B.Y., Zhu,Z.G. and Yu,Y.Y.
  TITLE     Helicobacter pylori induces promoter hypermethylation and
            downregulates gene expression of IRX1 transcription factor on human
            gastric mucosa
  JOURNAL   J. Gastroenterol. Hepatol. 26 (11), 1685-1690 (2011)
   PUBMED   21649733
  REMARK    GeneRIF: Helicobacter pylori infection contributes to IRX1 promoter
            methylation in gastric mucosa.
REFERENCE   4  (bases 1 to 1858)
  AUTHORS   Davis,O.S., Butcher,L.M., Docherty,S.J., Meaburn,E.L., Curtis,C.J.,
            Simpson,M.A., Schalkwyk,L.C. and Plomin,R.
  TITLE     A three-stage genome-wide association study of general cognitive
            ability: hunting the small effects
  JOURNAL   Behav. Genet. 40 (6), 759-767 (2010)
   PUBMED   20306291
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   5  (bases 1 to 1858)
  AUTHORS   Guo,X., Liu,W., Pan,Y., Ni,P., Ji,J., Guo,L., Zhang,J., Wu,J.,
            Jiang,J., Chen,X., Cai,Q., Li,J., Zhang,J., Gu,Q., Liu,B., Zhu,Z.
            and Yu,Y.
  TITLE     Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma
  JOURNAL   Oncogene 29 (27), 3908-3920 (2010)
   PUBMED   20440264
  REMARK    GeneRIF: IRX1 could potentially serve as a biomarker for gastric
            cancer.
            GeneRIF: Homeobox gene IRX1 is a tumor suppressor gene in gastric
            carcinoma.
REFERENCE   6  (bases 1 to 1858)
  AUTHORS   Trynka,G., Zhernakova,A., Romanos,J., Franke,L., Hunt,K.A.,
            Turner,G., Bruinenberg,M., Heap,G.A., Platteel,M., Ryan,A.W., de
            Kovel,C., Holmes,G.K., Howdle,P.D., Walters,J.R., Sanders,D.S.,
            Mulder,C.J., Mearin,M.L., Verbeek,W.H., Trimble,V., Stevens,F.M.,
            Kelleher,D., Barisani,D., Bardella,M.T., McManus,R., van Heel,D.A.
            and Wijmenga,C.
  TITLE     Coeliac disease-associated risk variants in TNFAIP3 and REL
            implicate altered NF-kappaB signalling
  JOURNAL   Gut 58 (8), 1078-1083 (2009)
   PUBMED   19240061
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 1858)
  AUTHORS   Lam,C.Y., Tam,P.O., Fan,D.S., Fan,B.J., Wang,D.Y., Lee,C.W.,
            Pang,C.P. and Lam,D.S.
  TITLE     A genome-wide scan maps a novel high myopia locus to 5p15
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 49 (9), 3768-3778 (2008)
   PUBMED   18421076
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 1858)
  AUTHORS   Bennett,K.L., Karpenko,M., Lin,M.T., Claus,R., Arab,K.,
            Dyckhoff,G., Plinkert,P., Herpel,E., Smiraglia,D. and Plass,C.
  TITLE     Frequently methylated tumor suppressor genes in head and neck
            squamous cell carcinoma
  JOURNAL   Cancer Res. 68 (12), 4494-4499 (2008)
   PUBMED   18559491
  REMARK    GeneRIF: Frequent methylation of IRX1 gene is associated with head
            and neck squamous cell carcinoma
REFERENCE   9  (bases 1 to 1858)
  AUTHORS   Ogura,K., Matsumoto,K., Kuroiwa,A., Isobe,T., Otoguro,T.,
            Jurecic,V., Baldini,A., Matsuda,Y. and Ogura,T.
  TITLE     Cloning and chromosome mapping of human and chicken Iroquois (IRX)
            genes
  JOURNAL   Cytogenet. Cell Genet. 92 (3-4), 320-325 (2001)
   PUBMED   11435706
REFERENCE   10 (bases 1 to 1858)
  AUTHORS   Lewis,M.T., Ross,S., Strickland,P.A., Snyder,C.J. and Daniel,C.W.
  TITLE     Regulated expression patterns of IRX-2, an Iroquois-class homeobox
            gene, in the human breast
  JOURNAL   Cell Tissue Res. 296 (3), 549-554 (1999)
   PUBMED   10370142
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY335938.1 and BC029160.1.
            On Aug 20, 2004 this sequence version replaced gi:41152512.
            
            Summary: This gene encodes a member of the Iroquois homeobox
            protein family. Homeobox genes in this family are involved in
            pattern formation in the embryo. The gene product has been
            identified as a tumor suppressor in gastric (PMID: 21602894,
            20440264) and head and neck cancers (PMID: 18559491). A pseudogene
            of this gene is located on chromosome 13. [provided by RefSeq, Dec
            2011].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY335938.1, BC029160.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025084 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-298               AY335938.1         1-298
            299-1858            BC029160.1         1-1560
FEATURES             Location/Qualifiers
     source          1..1858
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5p15.3"
     gene            1..1858
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /note="iroquois homeobox 1"
                     /db_xref="GeneID:79192"
                     /db_xref="HGNC:14358"
                     /db_xref="HPRD:16203"
                     /db_xref="MIM:606197"
     exon            1..328
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    14..16
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /note="upstream in-frame stop codon"
     CDS             53..1495
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /note="iroquois homeobox protein 1; homeodomain protein
                     IRXA1"
                     /codon_start=1
                     /product="iroquois-class homeodomain protein IRX-1"
                     /protein_id="NP_077313.3"
                     /db_xref="GI:51479177"
                     /db_xref="CCDS:CCDS34132.1"
                     /db_xref="GeneID:79192"
                     /db_xref="HGNC:14358"
                     /db_xref="HPRD:16203"
                     /db_xref="MIM:606197"
                     /translation="

MSFPQLGYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAELGGGAGAAAVTSVLGMYAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSDTEGDPEKAEDDEEIDLESIDIDKIDEHDGDQSNEDDEDKAEAPHAPAAPSALARDQGSPLAAADVLKPQDSPLGLAKEAPEPGSTRLLSPGAAAGGLQGAPHGKPKIWSLAETATSPDGAPKASPPPPAGHPGAHGPSAGAPLQHPAFLPSHGLYTCHIGKFSNWTNSAFLAQGSLLNMRSFLGVGAPHAAPHGPHLPAPPPPQPPVAIAPGALNGDKASVRSSPTLPERDLVPRPDSPAQQLKSPFQPVRDNSLAPQEGTPRILAALPSA

"
     misc_feature    434..619
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(434..448,452..454,512..514,530..532,569..571,
                     575..580,587..592,596..604,608..613)
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(440..442,449..451,578..580,587..592,599..601)
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    <989..1030
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /note="Motif in Iroquois-class homeodomain proteins
                     (only). Unknown function; Region: IRO; smart00548"
                     /db_xref="CDD:128821"
     variation       217
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370381455"
     variation       326
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374320644"
     exon            329..1364
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /inference="alignment:Splign:1.39.8"
     variation       341
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61757092"
     variation       361
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374868633"
     variation       370
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61743903"
     variation       385
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139010207"
     variation       394
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200766970"
     variation       396
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373456065"
     variation       471
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376527513"
     variation       483
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142274438"
     STS             490..554
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /standard_name="Irx3"
                     /db_xref="UniSTS:498475"
     variation       496
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370898776"
     variation       508
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374194797"
     variation       565
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377716175"
     variation       614
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372339050"
     variation       619
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199583658"
     variation       650
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143830823"
     variation       651
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148184826"
     variation       664
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371361752"
     variation       670
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61745751"
     variation       701
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61744556"
     variation       721
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373684329"
     variation       781
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367825706"
     variation       790
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141212131"
     variation       816
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370233658"
     variation       818
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376236311"
     variation       823
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370901303"
     variation       832
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61741521"
     variation       882
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368997184"
     variation       985
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373622269"
     variation       1012
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200644003"
     variation       1075
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369355630"
     variation       1084
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374559617"
     variation       1091
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368780470"
     variation       1126
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61746094"
     variation       1145
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201398092"
     variation       1151
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373494381"
     variation       1180
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374546765"
     variation       1199
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368097265"
     variation       1201
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371820903"
     variation       1252
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374378693"
     variation       1274
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375423008"
     variation       1280
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370996288"
     variation       1281
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372921884"
     variation       1300
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373574147"
     variation       1306
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:150332848"
     variation       1324
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:844154"
     variation       1336
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375641279"
     exon            1365..1437
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /inference="alignment:Splign:1.39.8"
     variation       1370
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374900719"
     variation       1375
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370521377"
     variation       1385
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:6884950"
     variation       1425
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376021360"
     exon            1438..1858
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /inference="alignment:Splign:1.39.8"
     variation       1461
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369886565"
     variation       1464
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200714951"
     variation       1476
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373795101"
     variation       1497
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201436384"
     variation       1526
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:11300064"
     variation       1528
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200638979"
     variation       1538
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377284296"
     variation       1596
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:111827405"
     STS             1609..1733
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /standard_name="RH98982"
                     /db_xref="UniSTS:86059"
     STS             1643..1736
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /standard_name="SHGC-56703"
                     /db_xref="UniSTS:52856"
     variation       1684
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:113372448"
     variation       1749
                     /gene="IRX1"
                     /gene_synonym="IRX-5; IRXA1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182715820"
ORIGIN      

ctccccgcgcctttaatactcgcccgctgcggcggtcgccgagtccgcggacatgtccttcccgcagctgggctacccgcagtacctgagcgccgcggggccgggcgcctacggcggcgagcgcccgggggtgctggccgcggccgctgcggcggctgccgccgcctcgtcgggccgaccgggggccgcggagctgggcggcggggcaggcgcggctgcagtcacctcggtgctgggcatgtacgcggcggcggggccgtacgcgggcgcgcccaactacagcgccttcctgccctacgccgcggatctcagcctcttctcgcagatgggctcgcagtatgaactgaaggacaaccctggggtgcaccccgccaccttcgcagcccacacggcgccggcttattacccctacggccagttccaatacggggaccccgggcggcccaagaacgccacccgcgagagcaccagcacgctcaaggcctggctcaacgagcaccgcaagaatccctaccccaccaagggcgagaagatcatgctggccatcatcaccaagatgaccctcacgcaggtctccacctggttcgccaacgcgcgccggcgcctcaagaaggagaacaaggtgacatggggagcgcgcagcaaggaccaggaagatggagcgctcttcggcagcgacaccgagggcgacccggagaaggccgaggacgacgaggagatcgacctggaaagcatcgacattgacaagatcgacgagcacgatggcgaccagagcaacgaggatgacgaggacaaggccgaggctccgcacgcgcccgcagccccttctgctcttgcccgggaccaaggctcgccgctggcagcagccgacgttctcaagccccaggactcgcccttgggcctggcaaaggaggccccagagccgggcagcacgcgcctgctgagccccggcgctgcagcgggcggcctgcagggtgcgccgcacggcaagcccaagatctggtcgctggcggagacagccacgagccccgacggtgcgcccaaggcttcgccaccaccacccgcgggccaccccggcgcgcacgggccctccgccggggcgccgctgcaacaccccgccttcctgcctagccacggactgtacacctgccacatcggcaagttctccaactggaccaacagcgcattcctcgcacagggctccctgctcaacatgcgctccttcctgggcgttggcgctccccacgccgcgccccatggccctcaccttcctgcacctccaccaccgcagccgccggtcgctattgccccgggggcactcaatggagacaaggcctcggtccgcagcagccccacgctcccagagagagacctcgtccccaggccagattcgccggcacagcagttaaagtcgcccttccagccggtacgcgacaactctctggccccgcaggagggaacgccgcggatcctagcagccctcccgtccgcctgattaagggtcttcttttacttttgcgggggggaggggggaggagttggggagggagggaatgtgggaggaattaagacaaatatttcagactggtgtaaaggacaaatatgacaacgacgtcaaggactcgcatccgtcgctttctgcagaaaggggcttcttcggtcccgagctcgcgtccaggtggccaggcctctgccggcggctccagtggctgcgattatcgggttcggtaaatgcccccacgtgcttgtgtctctttccccccttttctgtatatagagtggtttcagattgtaaatagcgcgtcagcgaacttgtctaaatcatatatttttgtctaataaactaaatgaaatgaca

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:79192 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:79192 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:79192 -> Biological process: GO:0072086 [specification of loop of Henle identity] evidence: IEA
            GeneID:79192 -> Biological process: GO:0072272 [proximal/distal pattern formation involved in metanephric nephron development] evidence: IEA
            GeneID:79192 -> Cellular component: GO:0005634 [nucleus] evidence: IEA