2025-05-09 19:14:55, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_014943 4373 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens zinc fingers and homeoboxes 2 (ZHX2), mRNA. ACCESSION NM_014943 VERSION NM_014943.3 GI:63079684 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 4373) AUTHORS Fuller,D.M., Zhu,M., Koonpaew,S., Nelson,M.I. and Zhang,W. TITLE The importance of the Erk pathway in the development of linker for activation of T cells-mediated autoimmunity JOURNAL J. Immunol. 189 (8), 4005-4013 (2012) PUBMED 22984075 REMARK GeneRIF: Expression of a constitutively active Raf transgene enhances lymphoproliferation, indicating a role for the Ras-MAPK pathway in linker for activation of T cells (LAT)-mediated autoimmune hyperproliferation. REFERENCE 2 (bases 1 to 4373) AUTHORS Ovsyannikova,I.G., Kennedy,R.B., O'Byrne,M., Jacobson,R.M., Pankratz,V.S. and Poland,G.A. TITLE Genome-wide association study of antibody response to smallpox vaccine JOURNAL Vaccine 30 (28), 4182-4189 (2012) PUBMED 22542470 REFERENCE 3 (bases 1 to 4373) AUTHORS Overlack,N., Goldmann,T., Wolfrum,U. and Nagel-Wolfrum,K. TITLE Gene repair of an Usher syndrome causing mutation by zinc-finger nuclease mediated homologous recombination JOURNAL Invest. Ophthalmol. Vis. Sci. 53 (7), 4140-4146 (2012) PUBMED 22661463 REMARK GeneRIF: simultaneous application of ZFN and rescue DNA induced gene repair of the disease-causing mutation on the genomic level, resulting in recovery of protein expression. Publication Status: Online-Only REFERENCE 4 (bases 1 to 4373) AUTHORS Nagel,S., Schneider,B., Meyer,C., Kaufmann,M., Drexler,H.G. and Macleod,R.A. TITLE Transcriptional deregulation of homeobox gene ZHX2 in Hodgkin lymphoma JOURNAL Leuk. Res. 36 (5), 646-655 (2012) PUBMED 22078940 REMARK GeneRIF: results demonstrate multiple mechanisms decreasing expression of tumor suppressor gene ZHX2 in Hodgkin lymphoma cell lines REFERENCE 5 (bases 1 to 4373) AUTHORS Nagel,S., Schneider,B., Rosenwald,A., Meyer,C., Kaufmann,M., Drexler,H.G. and MacLeod,R.A. TITLE t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2 JOURNAL Genes Chromosomes Cancer 50 (12), 996-1009 (2011) PUBMED 21987443 REMARK GeneRIF: Expression profiling of L-1236 cells following siRNA-mediated knockdown of ZHX2 showed inhibition of genes regulating differentiation and apoptosis, suggesting tumor suppressor activity of ZHX2. REFERENCE 6 (bases 1 to 4373) AUTHORS Liu,G., Clement,L.C., Kanwar,Y.S., Avila-Casado,C. and Chugh,S.S. TITLE ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome JOURNAL J. Biol. Chem. 281 (51), 39681-39692 (2006) PUBMED 17056598 REMARK GeneRIF: ZHX proteins 1, 2 and 3 are major transcriptional mediators of podocyte disease Erratum:[J Biol Chem. 2007 Apr 27;282(17):13140] REFERENCE 7 (bases 1 to 4373) AUTHORS de Andrade,T.G., Peterson,K.R., Cunha,A.F., Moreira,L.S., Fattori,A., Saad,S.T. and Costa,F.F. TITLE Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster JOURNAL Blood Cells Mol. Dis. 37 (2), 82-90 (2006) PUBMED 16952470 REMARK GeneRIF: ZHX2, a transcriptional repressor, may participate in globin gene regulation. REFERENCE 8 (bases 1 to 4373) AUTHORS Lim,J., Hao,T., Shaw,C., Patel,A.J., Szabo,G., Rual,J.F., Fisk,C.J., Li,N., Smolyar,A., Hill,D.E., Barabasi,A.L., Vidal,M. and Zoghbi,H.Y. TITLE A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration JOURNAL Cell 125 (4), 801-814 (2006) PUBMED 16713569 REFERENCE 9 (bases 1 to 4373) AUTHORS Kawata,H., Yamada,K., Shou,Z., Mizutani,T. and Miyamoto,K. TITLE The mouse zinc-fingers and homeoboxes (ZHX) family; ZHX2 forms a heterodimer with ZHX3 JOURNAL Gene 323, 133-140 (2003) PUBMED 14659886 REFERENCE 10 (bases 1 to 4373) AUTHORS Kawata,H., Yamada,K., Shou,Z., Mizutani,T., Yazawa,T., Yoshino,M., Sekiguchi,T., Kajitani,T. and Miyamoto,K. TITLE Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor JOURNAL Biochem. J. 373 (PT 3), 747-757 (2003) PUBMED 12741956 REMARK GeneRIF: identification as a transcriptional repressor COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM148156.1, BC042145.1, AC104316.3 and AI334237.1. On May 6, 2005 this sequence version replaced gi:31543977. Summary: The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC042145.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025081, ERS025082 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 BM148156.1 5-55 52-189 BM148156.1 57-194 190-3311 BC042145.1 102-3223 3312-3312 AC104316.3 95711-95711 3313-3576 BC042145.1 3225-3488 3577-3577 AC104316.3 95976-95976 3578-4225 BC042145.1 3490-4137 4226-4253 AC104316.3 96625-96652 4254-4354 BC042145.1 4166-4266 4355-4373 AI334237.1 1-19 c FEATURES Location/Qualifiers source 1..4373 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="8" /map="8q24.13" gene 1..4373 /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="zinc fingers and homeoboxes 2" /db_xref="GeneID:22882" /db_xref="HGNC:18513" /db_xref="HPRD:16458" /db_xref="MIM:609185" exon 1..285 /gene="ZHX2" /gene_synonym="AFR1; RAF" /inference="alignment:Splign:1.39.8" variation 40 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="" /replace="c" /db_xref="dbSNP:200249449" variation 42 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:57076121" variation 54 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="" /replace="t" /db_xref="dbSNP:370222853" variation 84 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:13261590" exon 286..348 /gene="ZHX2" /gene_synonym="AFR1; RAF" /inference="alignment:Splign:1.39.8" variation 295 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:16897571" exon 349..3085 /gene="ZHX2" /gene_synonym="AFR1; RAF" /inference="alignment:Splign:1.39.8" variation 383 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:192404933" variation 400 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:62522666" variation 405 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="t" /db_xref="dbSNP:144768655" misc_feature 472..474 /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="upstream in-frame stop codon" variation 515 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:116771558" variation 545 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:372182520" CDS 568..3081 /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="zinc-fingers and homeoboxes 2; transcription factor ZHX2; AFP regulator 1; regulator of AFP; alpha-fetoprotein regulator 1; zinc finger and homeodomain protein 2" /codon_start=1 /product="zinc fingers and homeoboxes protein 2" /protein_id="NP_055758.1" /db_xref="GI:7662342" /db_xref="CCDS:CCDS6336.1" /db_xref="GeneID:22882" /db_xref="HGNC:18513" /db_xref="HPRD:16458" /db_xref="MIM:609185" /translation="
MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDSWAAELENSSKENEVIEVKSMGESQSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIETTNHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKPEEITPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILGQTSLVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQLAIAASRHGRTYHAYPDFAPQKFKEKTQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQHQPMADDHGYDAVARKATKPMAESPKNGGDVVPQYYKDPKKLCEEDLEKLVTRVKVGSEPAKDCLPAKPSEATSDRSEGSSRDGQGSDENEESSVVDYVEVTVGEEDAISDRSDSWSQAAAEGVSELAESDSDCVPAEAGQA
" misc_feature 1150..1641 /gene="ZHX2" /gene_synonym="AFR1; RAF" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (Q9Y6X8.1); Region: Required for homodimerization" misc_feature 1354..2058 /gene="ZHX2" /gene_synonym="AFR1; RAF" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (Q9Y6X8.1); Region: Required for interaction with NFYA" misc_feature 1354..1905 /gene="ZHX2" /gene_synonym="AFR1; RAF" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (Q9Y6X8.1); Region: Required for repressor activity" misc_feature 1381..1530 /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; Region: homeodomain; cd00086" /db_xref="CDD:28970" misc_feature order(1423..1425,1441..1443,1480..1482,1486..1491, 1498..1503,1507..1515,1519..1524) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:28970" misc_feature order(1489..1491,1498..1503,1510..1512) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:28970" misc_feature 1516..1905 /gene="ZHX2" /gene_synonym="AFR1; RAF" /experiment="experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (Q9Y6X8.1); Region: Required for nuclear localization" misc_feature 1897..2055 /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; Region: homeodomain; cd00086" /db_xref="CDD:28970" misc_feature order(1897..1899,1903..1905,1954..1956,1972..1974, 2011..2013,2017..2022,2029..2034,2038..2046,2050..2055) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:28970" misc_feature order(1900..1902,2020..2022,2029..2034,2041..2043) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:28970" misc_feature 2155..2313 /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; Region: homeodomain; cd00086" /db_xref="CDD:28970" misc_feature order(2155..2169,2173..2175,2224..2226,2242..2244, 2281..2283,2287..2292,2299..2304,2308..2313) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:28970" misc_feature order(2161..2163,2170..2172,2290..2292,2299..2304, 2311..2313) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:28970" misc_feature 2470..2619 /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; Region: homeodomain; cd00086" /db_xref="CDD:28970" misc_feature order(2470..2472,2521..2523,2539..2541,2578..2580, 2584..2589,2596..2601,2605..2613,2617..2619) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:28970" misc_feature order(2587..2589,2596..2601,2608..2610) /gene="ZHX2" /gene_synonym="AFR1; RAF" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:28970" variation 593 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:147897583" variation 597 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:146817834" variation 608 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:140571061" variation 609 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:144209659" variation 623 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:201285505" variation 624 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:371607208" variation 640 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:146538096" variation 673 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:140461950" variation 690 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:140432187" variation 691 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:375028357" variation 714 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:368995594" variation 718 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:201553642" variation 741 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:35460327" variation 742 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:373708916" variation 754 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:61762976" variation 813 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:4871331" variation 828 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:61752912" variation 840 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:145165454" variation 849 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:377560517" variation 852 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:138740642" variation 855 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:4871332" variation 862 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:146938434" variation 897 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:73335724" variation 898 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:142031452" variation 903 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:150692889" variation 933 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:139940405" variation 942 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:149407080" variation 945 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:200640976" variation 968 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:201126119" variation 971 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:376815007" variation 1003 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:146351736" variation 1004 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:199651758" variation 1015 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="t" /db_xref="dbSNP:199765828" variation 1020 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:200717446" variation 1029 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:139634856" variation 1072 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:75046616" variation 1075 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:372944259" variation 1088 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:145158124" variation 1173 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:377327558" variation 1192 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:202189564" variation 1197 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:111854627" variation 1201 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:35760254" variation 1212 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:184731017" variation 1221 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:35865254" variation 1235 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:371184369" variation 1248 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:3204141" variation 1255 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:373301078" variation 1257 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:142739771" variation 1258 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:376446251" variation 1303 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:151010794" variation 1309 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:373784562" variation 1316 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:376295518" variation 1341 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:370672302" variation 1395 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:140865098" variation 1428 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:374124857" variation 1435 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="" /replace="g" /db_xref="dbSNP:5894650" variation 1482 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:368430233" variation 1487 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:372425134" variation 1526 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:34498734" variation 1542 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:376005552" variation 1572 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:36092924" variation 1584 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:16897795" variation 1587 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:200180193" variation 1591 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:116577713" variation 1596 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:372880887" variation 1614 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:146955427" variation 1615 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:375789703" variation 1630 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:113444944" variation 1636 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:9649951" variation 1638 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:200087554" variation 1658 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:369120446" variation 1659 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:372060090" variation 1663 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:375286966" variation 1668 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:143007490" variation 1671 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:202068049" variation 1680 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:201657146" variation 1692 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:373199431" variation 1717 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:201080427" variation 1727 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:370753355" variation 1729 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:142123946" variation 1755 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:375244930" variation 1770 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:3808600" variation 1789 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:139674940" variation 1789 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="" /replace="c" /db_xref="dbSNP:35054451" variation 1796 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:142894115" variation 1834 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:146090274" variation 1836 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:139727089" variation 1837 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:145385431" variation 1854 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:373531815" variation 1868 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:376976315" variation 1872 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:370328879" variation 1877 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:200614161" variation 1878 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:374578204" variation 1962 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:149774253" variation 1968 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:145695205" variation 1986 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:148698137" variation 1987 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:374724083" variation 1991 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:201501365" variation 2010 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:111726812" variation 2033 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:75116990" variation 2061 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:147834952" variation 2062 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:202088448" variation 2077 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:200660453" variation 2078 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:199705429" variation 2093 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="t" /db_xref="dbSNP:141332175" variation 2101 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:145188558" variation 2105 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:371741361" variation 2109 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:201353584" variation 2117 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:150960774" variation 2121 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:116461280" variation 2122 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:137944558" variation 2136 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:369677113" variation 2139 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:199852087" variation 2182 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:113667086" variation 2232 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:145887684" variation 2249 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:138450443" variation 2279 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:202202495" variation 2286 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:142958129" variation 2301 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:34092125" variation 2308 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:148330792" variation 2309 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:377449628" variation 2361 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:141456875" variation 2390 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:150834154" variation 2405 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:139249386" variation 2409 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:144568529" variation 2410 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:181151109" variation 2418 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:201212470" variation 2422 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:147432495" variation 2430 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:373967421" variation 2438 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:200270370" variation 2456 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:150510685" variation 2457 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:202138105" variation 2461 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:370990863" variation 2485 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:201376137" variation 2504 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:201034843" variation 2505 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:368727772" variation 2513 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:35319449" variation 2527 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="t" /db_xref="dbSNP:139727759" variation 2541 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:199783339" variation 2542 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:200753877" variation 2573 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:200646419" variation 2584 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:199503659" variation 2586 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:373654140" variation 2611 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:73335725" variation 2617 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:367798040" variation 2621 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:139442320" variation 2629 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:144984915" variation 2653 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:371624131" variation 2669 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="t" /db_xref="dbSNP:201478824" variation 2676 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:375035673" variation 2682 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:149065954" variation 2688 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:186468091" variation 2698 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:201952083" variation 2710 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:74549937" variation 2718 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:151153297" variation 2754 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:190859288" variation 2770 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:372010119" variation 2782 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:376664586" variation 2787 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:140232374" variation 2803 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:147430109" variation 2825 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:369846197" variation 2826 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:145190965" variation 2869 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:141390481" variation 2878 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:374001930" variation 2879 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:201110609" variation 2897 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:150252730" variation 2901 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:376562688" variation 2902 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:3802264" variation 2914 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:368973670" variation 2916 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:149388421" variation 2931 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:12548759" variation 2934 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:200959981" variation 2935 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:148101741" variation 2946 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:373507471" variation 2947 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:368779118" variation 2958 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:113010849" variation 2976 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:3802265" variation 2984 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:139793225" variation 3022 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:145283871" variation 3037 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:150570834" variation 3054 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:371036864" variation 3072 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:112921289" exon 3086..4359 /gene="ZHX2" /gene_synonym="AFR1; RAF" /inference="alignment:Splign:1.39.8" variation 3086 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:116211945" variation 3107 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:147584974" variation 3178 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:368914545" variation 3179 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:73335765" variation 3215 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:142028187" variation 3227 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:78762851" variation 3238 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:370726916" variation 3239 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:143039332" variation 3305 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:151130744" variation 3312 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:3802266" variation 3375 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:140399644" variation 3400 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:150374486" variation 3461 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:183384095" variation 3475 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:185732373" STS 3529..3686 /gene="ZHX2" /gene_synonym="AFR1; RAF" /standard_name="RH47173" /db_xref="UniSTS:18891" variation 3540 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:1129149" variation 3556 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:71514792" variation 3569 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:142539801" variation 3570 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="g" /replace="t" /db_xref="dbSNP:11989604" variation 3577 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:11544921" variation 3625 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:182792068" variation 3727 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:74563551" variation 3798 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:188304934" variation 3818 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:114291274" variation 3881 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:11985908" variation 3906 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:34002508" variation 4076 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="t" /db_xref="dbSNP:78437580" variation 4126 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:117127698" STS 4193..4326 /gene="ZHX2" /gene_synonym="AFR1; RAF" /standard_name="WI-14759" /db_xref="UniSTS:70649" STS 4195..4317 /gene="ZHX2" /gene_synonym="AFR1; RAF" /standard_name="RH41900" /db_xref="UniSTS:47720" variation 4197 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:192789466" STS 4199..4326 /gene="ZHX2" /gene_synonym="AFR1; RAF" /standard_name="G59722" /db_xref="UniSTS:137020" variation 4226 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="g" /db_xref="dbSNP:7758" variation 4253 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:2833" variation 4255 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="c" /replace="t" /db_xref="dbSNP:182290370" variation 4292 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="g" /db_xref="dbSNP:370311035" variation 4323 /gene="ZHX2" /gene_synonym="AFR1; RAF" /replace="a" /replace="c" /db_xref="dbSNP:375421915" polyA_signal 4326..4331 /gene="ZHX2" /gene_synonym="AFR1; RAF" polyA_site 4359 /gene="ZHX2" /gene_synonym="AFR1; RAF" ORIGIN
ttttggcgtagattccccactgatcgaggcattttttttccctttttttttcctttttttttttcttttaaaaattttggccatcgttctccgtacgggggctttttctgtctgtctgtctggctggcaggctggctttccccctctttcccacggagcccgagccgggcgcccggtggggagtggggagtgggtggggggagccagcagagttccattttggaacgcccgtgccgcgtctccgcgttcccagcccgggtccccgcgttcacagccccagcgcaggtctggatgtaccgactgcttttggaataaaaagattcccaggatgtgagcaacacgggaccgatatgatgcttcctggtgtgtttagtggttggtgccattccaattttctgtgctgaaatcattctgaaaactcaaacagtagacttcagcacacaaggaaagccaaagccatttgagggggaataaagccaaaagcctttcaccttattcgttccaagaatctcaccgccccctccttatccccctccaaaaataagccattgcacacagacaggcagcatggctagcaaacgaaaatctacaactccatgcatggttcggacatcacaagtagtagaacaagatgtgcccgaggaagtagacagggccaaagagaaaggaatcggcacaccacagcctgacgtggccaaggacagttgggcagcagaacttgaaaactcttccaaagaaaacgaagtgatagaggtgaaatctatgggggaaagccagtccaaaaaactccaaggtggttatgagtgcaaatactgcccctactccacgcaaaacctgaacgagttcacggagcatgtcgacatgcagcatcccaacgtgattctcaaccccctctacgtgtgtgcagaatgtaacttcacaaccaaaaagtacgactccctatccgaccacaactccaagttccatcccggggaggccaacttcaagctgaagttaattaaacgcaataatcaaactgtcttggaacagtccatcgaaaccaccaaccatgtcgtgtccatcaccaccagtggccctggaactggtgacagtgattctgggatctcggtgagtaaaacccccatcatgaagcctggaaaaccaaaagcggatgccaagaaggtgcccaagaagcccgaggagatcacccccgagaaccacgtggaagggaccgcccgcctggtgacagacacagctgagatcctctcgagactcggcggggtggagctcctccaagacacattaggacacgtcatgccttctgtacagctgccaccaaatatcaaccttgtgcccaaggtccctgtcccactaaatactaccaaatacaactctgccctggatacaaatgccacgatgatcaactctttcaacaagtttccttacccgacccaggctgagttgtcctggctgacagctgcctccaaacacccagaggagcacatcagaatctggtttgccacccagcgcttaaagcatggcatcagctggtccccagaagaggtggaggaggcccggaagaagatgttcaacggcaccatccagtcagtacccccgaccatcactgtgctgcccgcccagttggcccccacaaaggtgacgcagcccatcctccagacggctctaccgtgccagatcctcggccagactagcctggtgctgactcaggtgaccagcgggtcaacaaccgtctcttgctcccccatcacacttgccgtggcaggagtcaccaaccatggccagaagagacccttggtgactccccaagctgcccccgaacccaagcgtccacacatcgctcaggtgccagagcccccacccaaggtggccaaccccccgctcacaccagccagtgaccgcaagaagacaaaggagcagatagcacatctcaaggccagctttctccagagccagttccctgacgatgccgaggtttaccggctcatcgaggtgactggccttgccaggagcgagatcaagaagtggttcagtgaccaccgatatcggtgtcaaaggggcatcgtccacatcaccagcgaatcccttgccaaagaccagttggccatcgcggcctcccgacacggtcgcacgtatcatgcgtacccagactttgccccccagaagttcaaagagaaaacacagggtcaggttaaaatcttggaagacagctttttgaaaagttcttttcctacccaagcagaactggatcggctaagggtggagaccaagctgagcaggagagagatcgactcctggttctcggagaggcggaagcttcgagacagcatggaacaagctgtcttggattccatggggtctggcaaaaaaggccaagatgtgggagcccccaatggtgctctgtctcgactcgaccagctctccggtgcccagttaacaagttctctgcccagcccttcgccagcaattgcaaaaagtcaagaacaggttcatctcctgaggagcacgtttgcaagaacccagtggcctactccccaggagtacgaccagttagcggccaagactggcctggtccgaactgagattgtgcgttggttcaaggagaacagatgcttgctgaaaacgggaaccgtgaagtggatggagcagtaccagcaccagcccatggcagatgatcacggctacgatgccgtagcaaggaaagcaacaaaacccatggccgagagcccaaagaacgggggtgatgtggttccacaatattacaaggaccccaaaaagctctgcgaagaggacttggagaagttggtgaccagggtaaaagtaggcagcgagccagcaaaagactgtttgccagcaaagccctcagaggccacctcagaccggtcagagggcagcagccgggacggccagggtagcgacgagaacgaggagtcgagcgttgtggattacgtggaggtgacggtcggggaggaggatgcgatctcagatagatcagatagctggagtcaggctgcggcagaaggtgtgtcggaactggctgaatcagactccgactgcgtccctgcagaggctggccaggcctagacagggaagtctgttagaactgctgtgctgatcaacgggacgctccgtctttgaagaaagaagagatggtctctccccagccatgggccacccttgccagtgactccaagtggaactacttagctcgcgtgtgcctggagggtgcgggaagtccagcgactctcagacgcacctcccagaggaccggtgggaattgttcatagtgccaaagtcctactactgcgttttcaatgggtccttgtacatagtttgctcctctgccctagccctcacctcttgctatactggaaccgatttgtacaatgtgggaattttgttacctttttaatcaagggcaacttccttttccagcactaccattgtaaggtttttttcaggagggagggctaaccaccttgcttttctcttttctctttttcttttttttatttttgttttattaatttggggaaaggggtgttagcattagtgccatgatatctactggattttaagtagggagactttatttttaaaggtaggttgaaatttgggagatttctcggcaggaagggctgaaatccaggcccctgtctcaacttggagagaggtgacagacggcagatcttccaaatcaaattcctttccagttcttcccctggctgcctttttgggggtccctgccttagccccacacaaggctttctgaactgccaagaggggatctggcttctcaactgctcggcctcttgggccaggctgtgcccagccagccctgggagaactgggtagcaggtggctgacttctttaagcacctttctaaataccagcagaagaggctcccgcctctgttagcatgatcagtactattgtgacattaaaacaacaacaataagatcttcctatctggagggtacagaggtgaatggctttggttttcatttctcttcttcactgccttttctcggtgtggtatttgacaagattttagctcaaagcctcaccatgaattgattttttttgtttgtgtgtgtgtttgttttgggacaattttagatacctgagtgcactttttcagttagtcctaacttttaaaagaaggaaaaccaagagacatatctggtgtacgtgttgcagtatgaactctggttgcaatccctccccgtcccacactgccccccatttgagtacaccgcacaagtcaaacgctaggaagtttgaataaaaccaatttttctaacttgttgctcatttgttgtaactcaataaagcaaagactaaacatttttataacctttaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:22882 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA GeneID:22882 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: IDA GeneID:22882 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:22882 -> Molecular function: GO:0042803 [protein homodimerization activity] evidence: IDA GeneID:22882 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA GeneID:22882 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA GeneID:22882 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IDA GeneID:22882 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA GeneID:22882 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA GeneID:22882 -> Biological process: GO:0006402 [mRNA catabolic process] evidence: IEA GeneID:22882 -> Biological process: GO:0035019 [somatic stem cell maintenance] evidence: IEA GeneID:22882 -> Biological process: GO:0045665 [negative regulation of neuron differentiation] evidence: IEA GeneID:22882 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IDA GeneID:22882 -> Cellular component: GO:0005634 [nucleus] evidence: IDA GeneID:22882 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA GeneID:22882 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA GeneID:22882 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
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