LOCUS       NM_014213               1902 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens homeobox D9 (HOXD9), mRNA.
ACCESSION   NM_014213
VERSION     NM_014213.3  GI:194363767
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1902)
  AUTHORS   Tian,W., Zhao,L., Wang,J., Suo,P., Wang,J., Cheng,L., Cheng,Z.,
            Jia,J., Kan,S., Wang,B. and Ma,X.
  TITLE     Association analysis between HOXD9 genes and the development of
            developmental dysplasia of the hip in Chinese female Han population
  JOURNAL   BMC Musculoskelet Disord 13, 59 (2012)
   PUBMED   22520331
  REMARK    GeneRIF: The association between SNP of the HOXD9 gene and
            developmental hip dysplasia reached significance in Chinese Han
            females.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1902)
  AUTHORS   Tabuse,M., Ohta,S., Ohashi,Y., Fukaya,R., Misawa,A., Yoshida,K.,
            Kawase,T., Saya,H., Thirant,C., Chneiweiss,H., Matsuzaki,Y.,
            Okano,H., Kawakami,Y. and Toda,M.
  TITLE     Functional analysis of HOXD9 in human gliomas and glioma cancer
            stem cells
  JOURNAL   Mol. Cancer 10, 60 (2011)
   PUBMED   21600039
  REMARK    GeneRIF: Our results suggest that HOXD9 may be a novel marker of
            GCSCs and cell proliferation and/or survival factor in gliomas and
            glioma cancer stem-like cells, and a potential therapeutic target.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1902)
  AUTHORS   Meyer,T.E., Verwoert,G.C., Hwang,S.J., Glazer,N.L., Smith,A.V., van
            Rooij,F.J., Ehret,G.B., Boerwinkle,E., Felix,J.F., Leak,T.S.,
            Harris,T.B., Yang,Q., Dehghan,A., Aspelund,T., Katz,R., Homuth,G.,
            Kocher,T., Rettig,R., Ried,J.S., Gieger,C., Prucha,H., Pfeufer,A.,
            Meitinger,T., Coresh,J., Hofman,A., Sarnak,M.J., Chen,Y.D.,
            Uitterlinden,A.G., Chakravarti,A., Psaty,B.M., van Duijn,C.M.,
            Kao,W.H., Witteman,J.C., Gudnason,V., Siscovick,D.S., Fox,C.S. and
            Kottgen,A.
  CONSRTM   Genetic Factors for Osteoporosis Consortium; Meta Analysis of
            Glucose and Insulin Related Traits Consortium
  TITLE     Genome-wide association studies of serum magnesium, potassium, and
            sodium concentrations identify six Loci influencing serum magnesium
            levels
  JOURNAL   PLoS Genet. 6 (8) (2010)
   PUBMED   20700443
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1902)
  AUTHORS   Ester,A.R., Weymouth,K.S., Burt,A., Wise,C.A., Scott,A.,
            Gurnett,C.A., Dobbs,M.B., Blanton,S.H. and Hecht,J.T.
  TITLE     Altered transmission of HOX and apoptotic SNPs identify a potential
            common pathway for clubfoot
  JOURNAL   Am. J. Med. Genet. A 149A (12), 2745-2752 (2009)
   PUBMED   19938081
  REMARK    GeneRIF: Observational study of gene-disease association and
            gene-gene interaction. (HuGE Navigator)
REFERENCE   5  (bases 1 to 1902)
  AUTHORS   Yerges,L.M., Klei,L., Cauley,J.A., Roeder,K., Kammerer,C.M.,
            Moffett,S.P., Ensrud,K.E., Nestlerode,C.S., Marshall,L.M.,
            Hoffman,A.R., Lewis,C., Lang,T.F., Barrett-Connor,E., Ferrell,R.E.,
            Orwoll,E.S. and Zmuda,J.M.
  CONSRTM   MrOS Research Group
  TITLE     High-density association study of 383 candidate genes for
            volumetric BMD at the femoral neck and lumbar spine among older men
  JOURNAL   J. Bone Miner. Res. 24 (12), 2039-2049 (2009)
   PUBMED   19453261
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 1902)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   7  (bases 1 to 1902)
  AUTHORS   Zappavigna,V., Renucci,A., Izpisua-Belmonte,J.C., Urier,G.,
            Peschle,C. and Duboule,D.
  TITLE     HOX4 genes encode transcription factors with potential auto- and
            cross-regulatory capacities
  JOURNAL   EMBO J. 10 (13), 4177-4187 (1991)
   PUBMED   1756725
REFERENCE   8  (bases 1 to 1902)
  AUTHORS   McAlpine,P.J. and Shows,T.B.
  TITLE     Nomenclature for human homeobox genes
  JOURNAL   Genomics 7 (3), 460 (1990)
   PUBMED   1973146
REFERENCE   9  (bases 1 to 1902)
  AUTHORS   Acampora,D., D'Esposito,M., Faiella,A., Pannese,M., Migliaccio,E.,
            Morelli,F., Stornaiuolo,A., Nigro,V., Simeone,A. and Boncinelli,E.
  TITLE     The human HOX gene family
  JOURNAL   Nucleic Acids Res. 17 (24), 10385-10402 (1989)
   PUBMED   2574852
REFERENCE   10 (bases 1 to 1902)
  AUTHORS   Oliver,G., Sidell,N., Fiske,W., Heinzmann,C., Mohandas,T.,
            Sparkes,R.S. and De Robertis,E.M.
  TITLE     Complementary homeo protein gradients in developing limb buds
  JOURNAL   Genes Dev. 3 (5), 641-650 (1989)
   PUBMED   2568311
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC044855.1, X59372.1 and
            BU732638.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Jul 23, 2008 this sequence version replaced gi:23397673.
            
            Summary: This gene belongs to the homeobox family of genes. The
            homeobox genes encode a highly conserved family of transcription
            factors that play an important role in morphogenesis in all
            multicellular organisms. Mammals possess four similar homeobox gene
            clusters, HOXA, HOXB, HOXC and HOXD, located on different
            chromosomes, consisting of 9 to 11 genes arranged in tandem. This
            gene is one of several homeobox HOXD genes located at 2q31-2q37
            chromosome regions. Deletions that removed the entire HOXD gene
            cluster or 5' end of this cluster have been associated with severe
            limb and genital abnormalities. The exact role of this gene has not
            been determined. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC044855.1, X59372.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025084 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-512               BC044855.1         1-512
            513-739             X59372.1           435-661
            740-1791            BC044855.1         740-1791
            1792-1902           BU732638.1         1-111               c
FEATURES             Location/Qualifiers
     source          1..1902
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q31.1"
     gene            1..1902
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /note="homeobox D9"
                     /db_xref="GeneID:3235"
                     /db_xref="HGNC:5140"
                     /db_xref="MIM:142982"
     exon            1..901
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /inference="alignment:Splign:1.39.8"
     variation       22
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75770990"
     misc_feature    34..36
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /note="upstream in-frame stop codon"
     variation       38
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200294272"
     variation       44
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:144600979"
     variation       53
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369960160"
     variation       59
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201264942"
     CDS             85..1143
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /note="homeo box D9; Hox-4.3, mouse, homolog of; homeobox
                     protein Hox-4C; homeobox protein Hox-5.2"
                     /codon_start=1
                     /product="homeobox protein Hox-D9"
                     /protein_id="NP_055028.3"
                     /db_xref="GI:194363768"
                     /db_xref="CCDS:CCDS2267.2"
                     /db_xref="GeneID:3235"
                     /db_xref="HGNC:5140"
                     /db_xref="MIM:142982"
                     /translation="

MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD

"
     misc_feature    115..717
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /note="Hox9 activation region; Region: Hox9_act;
                     pfam04617"
                     /db_xref="CDD:191048"
     misc_feature    940..1095
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(940..954,958..960,1009..1011,1027..1029,1066..1068,
                     1072..1077,1084..1089,1093..1095)
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(946..948,955..957,1075..1077,1084..1089)
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     variation       93
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:28637717"
     variation       99
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372918813"
     variation       104
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:186057872"
     variation       113
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370320649"
     variation       131
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375504706"
     variation       191
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373455323"
     variation       198
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202080706"
     variation       208
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371998550"
     variation       214
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376364642"
     variation       246
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369936511"
     variation       337
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113296661"
     variation       382
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201091824"
     variation       412
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202035456"
     variation       547
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:191379716"
     variation       603
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:711821"
     variation       644
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370816034"
     variation       647
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:34862292"
     variation       667
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201217794"
     variation       668
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200376660"
     variation       762
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:376543466"
     variation       780
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370587160"
     variation       803
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373207184"
     variation       804
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377282327"
     variation       810
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111362732"
     variation       820
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:367821438"
     STS             839..939
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /standard_name="Hoxd9"
                     /db_xref="UniSTS:474753"
     variation       878..879
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace=""
                     /replace="gca"
                     /db_xref="dbSNP:56007470"
     variation       878
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200417886"
     variation       879..880
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace=""
                     /replace="gca"
                     /db_xref="dbSNP:35578003"
     variation       881..882
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace=""
                     /replace="agc"
                     /replace="gca"
                     /db_xref="dbSNP:10665265"
     variation       890
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace=""
                     /replace="gca"
                     /db_xref="dbSNP:74937422"
     variation       891
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200391181"
     variation       896
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370326114"
     exon            902..1885
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /inference="alignment:Splign:1.39.8"
     STS             945..1129
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /standard_name="Hoxd9"
                     /db_xref="UniSTS:143399"
     STS             948..1184
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /standard_name="RH18119"
                     /db_xref="UniSTS:49395"
     variation       950
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376874077"
     variation       967
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371557389"
     variation       999
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202030114"
     variation       1005
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35649704"
     variation       1036
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138258352"
     variation       1044
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112934078"
     variation       1052
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146173388"
     variation       1071
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35299188"
     variation       1078
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368352732"
     STS             1092..1874
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /standard_name="HOXD9_1230"
                     /db_xref="UniSTS:277324"
     variation       1137
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372008744"
     variation       1147
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375399643"
     variation       1254..1256
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace=""
                     /replace="ctt"
                     /db_xref="dbSNP:367897393"
     variation       1260..1261
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:373038108"
     variation       1260
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:62188694"
     variation       1263
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:711822"
     variation       1263
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:201376389"
     variation       1266
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192165308"
     variation       1345
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:141233271"
     variation       1366
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367725226"
     variation       1412
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:182787856"
     variation       1562
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112240872"
     variation       1598
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114041172"
     variation       1680
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371698532"
     variation       1820
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376636797"
     variation       1828
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13424545"
     variation       1831
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:117352909"
     polyA_signal    1860..1865
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
     polyA_site      1885
                     /gene="HOXD9"
                     /gene_synonym="Hox-4.3; Hox-5.2; HOX4; HOX4C"
ORIGIN      

cgcgaccaatggtggaggctgcagcctgcgaactagtcggtggctcgggcgccggcggggagctgctcggcggcggacagtgtaatgttgggtgggagtgcgggacgcctcaaaatgtcttccagtggcaccctcagcaactactacgtggactcgcttataggccatgagggcgacgaggtgttcgcggcgcgcttcgggccgccggggccaggcgcgcagggccggcctgcaggtgtggctgatggcccggccgccaccgccgccgagttcgcctcgtgtagttttgcccccagatcggccgtgttctctgcctcgtggtccgcggtgccctcccagcccccggcagcggcggcgatgagcggcctctaccacccgtacgttcccccgccgcccctggccgcctctgcctccgagcccggccgctacgtgcgctcctggatggagccgctgcccggcttcccgggcggtgcgggcggtggcggtggtggtggaggcggcggtccgggccgcggtcccagccctggccccagcggcccagccaacgggcgccactacgggattaagcctgaaacccgagcggccccggcccccgccacggccgcctccaccacctcctcctcctccacttccttatcctcctcctccaaacggactgagtgctccgtggcccgggagtcccaggggagcagcggccccgagttctcgtgcaactcgttcctgcaggagaaggcggcagcggcgacggggggaaccgggcctggggcagggatcggggccgcgactgggacgggcggctcgtcggagccctcagcttgcagcgaccacccgatcccaggctgttcgctgaaggaggaggagaagcagcattcgcagccgcagcagcagcaacttgacccaaacaaccccgccgcgaactggatccacgctcgctccacccggaaaaagcgctgtccctacaccaaataccagacgcttgagctggagaaagaattcctcttcaacatgtacctcacccgggaccggcgctacgaggtggccaggattctcaacctaacagagagacaggtcaaaatctggtttcagaaccgtaggatgaaaatgaaaaagatgagcaaggagaaatgccccaaaggagactgacccggcgcggtgctggcgggagcgctcaagggcagcggatttgttgttgttgctgttttcctttgtgggtgtttggtgcttgatttccagaaactctccagcgacttggacttcttcttctttttttttttctttttagatagaagtgactgtgtggttggtctctgaggtatttgggggactctgtatttgctcgtttacgtgttggaaaaaccaagtggctttggggtttcgccctatcccactccctctctttcctgctccattggttccttaagaaatgctatattttgtgagtgcaagctggcttggggagccctctcttgtgtaaatgtcccccatgtttctgaaaagtgctgtagtttagtcccctcacccccagcactgcccaaacaggggccaagtgcgccccaattccaagaatgaaggcagagcgacaacagtgcggacaccccggctgctagcccacggtgaagcccggcggggttgcccaccagttgcgaaagccccctttcctcagggagcacgcgggacctcggtggagatctccagtgaggcttagaggagcccagggcctcgggcgggttggggtttgtcctcagtgcattggacgcgctgctctctcccctgaaggctgggctcgcgtgggcggccgcgggtggtggccctcccggttcctgcccgaggaccagttgtaaatgttactgcttcctactaataaatgctgacctgatcaaatggaaaaaaaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:3235 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:3235 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:3235 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:3235 -> Biological process: GO:0007519 [skeletal muscle tissue development] evidence: IEA
            GeneID:3235 -> Biological process: GO:0008344 [adult locomotory behavior] evidence: IEA
            GeneID:3235 -> Biological process: GO:0009952 [anterior/posterior pattern specification] evidence: IEA
            GeneID:3235 -> Biological process: GO:0009954 [proximal/distal pattern formation] evidence: IEA
            GeneID:3235 -> Biological process: GO:0030879 [mammary gland development] evidence: IEA
            GeneID:3235 -> Biological process: GO:0035115 [embryonic forelimb morphogenesis] evidence: IEA
            GeneID:3235 -> Biological process: GO:0035137 [hindlimb morphogenesis] evidence: IEA
            GeneID:3235 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:3235 -> Biological process: GO:0048704 [embryonic skeletal system morphogenesis] evidence: IEA
            GeneID:3235 -> Biological process: GO:0048935 [peripheral nervous system neuron development] evidence: IEA
            GeneID:3235 -> Cellular component: GO:0005634 [nucleus] evidence: IEA