LOCUS       NM_012476               1163 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens ventral anterior homeobox 2 (VAX2), mRNA.
ACCESSION   NM_012476
VERSION     NM_012476.2  GI:205277331
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1163)
  AUTHORS   Lopes,M.C., Hysi,P.G., Verhoeven,V.J., Macgregor,S., Hewitt,A.W.,
            Montgomery,G.W., Cumberland,P., Vingerling,J.R., Young,T.L., van
            Duijn,C.M., Oostra,B., Uitterlinden,A.G., Rahi,J.S., Mackey,D.A.,
            Klaver,C.C., Andrew,T. and Hammond,C.J.
  TITLE     Identification of a candidate gene for astigmatism
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 54 (2), 1260-1267 (2013)
   PUBMED   23322567
  REMARK    GeneRIF: A susceptibility locus was identified with lead single
            nucleotide polymorphism rs3771395 on chromosome 2p13.3
            (meta-analysis, P = 1.97 x 10(-7)) in the VAX2 gene for
            astigmatism.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1163)
  AUTHORS   Oshikawa,M., Tsutsui,C., Ikegami,T., Fuchida,Y., Matsubara,M.,
            Toyama,S., Usami,R., Ohtoko,K. and Kato,S.
  TITLE     Full-length transcriptome analysis of human retina-derived cell
            lines ARPE-19 and Y79 using the vector-capping method
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 52 (9), 6662-6670 (2011)
   PUBMED   21697133
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1163)
  AUTHORS   Bailey,S.D., Xie,C., Do,R., Montpetit,A., Diaz,R., Mohan,V.,
            Keavney,B., Yusuf,S., Gerstein,H.C., Engert,J.C. and Anand,S.
  CONSRTM   DREAM investigators
  TITLE     Variation at the NFATC2 locus increases the risk of
            thiazolidinedione-induced edema in the Diabetes REduction
            Assessment with ramipril and rosiglitazone Medication (DREAM) study
  JOURNAL   Diabetes Care 33 (10), 2250-2253 (2010)
   PUBMED   20628086
  REMARK    GeneRIF: Observational study of gene-disease association,
            gene-environment interaction, and pharmacogenomic / toxicogenomic.
            (HuGE Navigator)
REFERENCE   4  (bases 1 to 1163)
  AUTHORS   Talmud,P.J., Drenos,F., Shah,S., Shah,T., Palmen,J., Verzilli,C.,
            Gaunt,T.R., Pallas,J., Lovering,R., Li,K., Casas,J.P., Sofat,R.,
            Kumari,M., Rodriguez,S., Johnson,T., Newhouse,S.J., Dominiczak,A.,
            Samani,N.J., Caulfield,M., Sever,P., Stanton,A., Shields,D.C.,
            Padmanabhan,S., Melander,O., Hastie,C., Delles,C., Ebrahim,S.,
            Marmot,M.G., Smith,G.D., Lawlor,D.A., Munroe,P.B., Day,I.N.,
            Kivimaki,M., Whittaker,J., Humphries,S.E. and Hingorani,A.D.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am. J. Hum. Genet. 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   5  (bases 1 to 1163)
  AUTHORS   Holland,P.W., Booth,H.A. and Bruford,E.A.
  TITLE     Classification and nomenclature of all human homeobox genes
  JOURNAL   BMC Biol. 5, 47 (2007)
   PUBMED   17963489
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1163)
  AUTHORS   Beaty,T.H., Hetmanski,J.B., Fallin,M.D., Park,J.W., Sull,J.W.,
            McIntosh,I., Liang,K.Y., Vanderkolk,C.A., Redett,R.J.,
            Boyadjiev,S.A., Jabs,E.W., Chong,S.S., Cheah,F.S., Wu-Chou,Y.H.,
            Chen,P.K., Chiu,Y.F., Yeow,V., Ng,I.S., Cheng,J., Huang,S., Ye,X.,
            Wang,H., Ingersoll,R. and Scott,A.F.
  TITLE     Analysis of candidate genes on chromosome 2 in oral cleft
            case-parent trios from three populations
  JOURNAL   Hum. Genet. 120 (4), 501-518 (2006)
   PUBMED   16953426
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 1163)
  AUTHORS   Barbieri,A.M., Lupo,G., Bulfone,A., Andreazzoli,M., Mariani,M.,
            Fougerousse,F., Consalez,G.G., Borsani,G., Beckmann,J.S.,
            Barsacchi,G., Ballabio,A. and Banfi,S.
  TITLE     A homeobox gene, vax2, controls the patterning of the eye
            dorsoventral axis
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 96 (19), 10729-10734 (1999)
   PUBMED   10485894
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from Y17791.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Sep 19, 2008 this sequence version replaced gi:7110734.
            
            Summary: This gene encodes a homeobox protein and is almost
            exclusively expressed in the ventral portion of the retina during
            development. In mouse studies, this gene was found to be required
            for the correct formation of the optic fissure and other aspects of
            retinal development. [provided by RefSeq, Sep 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: Y17791.1, AB593145.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025087, ERS025088 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-965               Y17791.1           1-965
            966-1163            Y17791.1           967-1164
FEATURES             Location/Qualifiers
     source          1..1163
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p13"
     gene            1..1163
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /note="ventral anterior homeobox 2"
                     /db_xref="GeneID:25806"
                     /db_xref="HGNC:12661"
                     /db_xref="HPRD:05051"
                     /db_xref="MIM:604295"
     exon            1..279
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /inference="alignment:Splign:1.39.8"
     variation       5
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2234494"
     variation       28..34
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace=""
                     /replace="tcagcat"
                     /db_xref="dbSNP:151056092"
     CDS             33..905
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /codon_start=1
                     /product="ventral anterior homeobox 2"
                     /protein_id="NP_036608.1"
                     /db_xref="GI:7110735"
                     /db_xref="CCDS:CCDS1911.1"
                     /db_xref="GeneID:25806"
                     /db_xref="HGNC:12661"
                     /db_xref="HPRD:05051"
                     /db_xref="MIM:604295"
                     /translation="

MGDGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSASASPPLPPPLPAVCFSSAPLLDLPAGYELGSSAFEPYSWLERKVGSASSCKKANT

"
     misc_feature    339..515
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(339..353,357..359,408..410,426..428,465..467,
                     471..476,483..488,492..500,504..509)
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(345..347,354..356,474..476,483..488,495..497)
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     variation       75
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2234495"
     variation       87
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61275549"
     variation       102
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2234496"
     variation       168
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200413581"
     variation       172
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61753452"
     exon            280..467
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /inference="alignment:Splign:1.39.8"
     variation       297
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139950648"
     variation       311
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200929150"
     variation       326
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:183938302"
     variation       333
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145801795"
     variation       343
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199781570"
     variation       378
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145436494"
     variation       396..397
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35311617"
     variation       400
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142434739"
     variation       421
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148304948"
     variation       423
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200582274"
     variation       426
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150176075"
     variation       435
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:141797280"
     variation       441
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137915944"
     variation       442
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145930788"
     variation       447
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:56075602"
     variation       459
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375241285"
     exon            468..1147
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /inference="alignment:Splign:1.39.8"
     variation       490
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145503713"
     variation       512
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201302985"
     variation       526
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145701453"
     variation       529
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:368226464"
     variation       530
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200905563"
     variation       534
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202064044"
     variation       554
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372067757"
     variation       572
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375536449"
     variation       581
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199640308"
     variation       582
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201863357"
     variation       637
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369829011"
     variation       641
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372003294"
     variation       647
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200923058"
     variation       652
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375782827"
     variation       654
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143185254"
     variation       661
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2234498"
     variation       682
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372789757"
     variation       689
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142431637"
     variation       715
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2234499"
     variation       724
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376990356"
     variation       743
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144443163"
     variation       746
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:144120968"
     variation       750
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368886091"
     variation       751
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:140956448"
     variation       757
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183405602"
     variation       770
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:139309761"
     variation       774
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149973402"
     variation       788
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140378557"
     variation       791
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146481119"
     variation       793
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2234500"
     variation       795
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200750550"
     variation       818
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372164857"
     variation       828
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377703915"
     variation       832
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141208791"
     variation       857
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2234501"
     variation       861
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200587085"
     variation       863
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373583380"
     variation       876
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147336899"
     STS             877..1021
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /standard_name="PMC17951P1"
                     /db_xref="UniSTS:271660"
     variation       910
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368359306"
     variation       992
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2270262"
     variation       1017
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371015613"
     variation       1020
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188835580"
     variation       1034
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:139189301"
     variation       1069
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:55783951"
     variation       1081
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144708042"
     variation       1103
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139621053"
     polyA_signal    1117..1122
                     /gene="VAX2"
                     /gene_synonym="DRES93"
     variation       1122
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144446709"
     variation       1137
                     /gene="VAX2"
                     /gene_synonym="DRES93"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146118364"
     polyA_site      1143
                     /gene="VAX2"
                     /gene_synonym="DRES93"
     polyA_site      1147
                     /gene="VAX2"
                     /gene_synonym="DRES93"
ORIGIN      

ccgccgtagaggggttggcagtggcggtcagcatgggcgatgggggcgccgagcgcgaccggggccccgcgcgccgggcggagtctggtggcggcggtgggcgctgcggagaccgcagcggagcgggggacttgcgagctgatggcggtggccacagcccaacggaggtggccgggacctcagcctccagtcccgcaggctccagggagagtggagccgacagcgacgggcagcccgggcccggcgaggcagaccactgccgccgcatactggtgcgagatgccaaagggacaattcgggaaattgtcctgcctaagggcctggacctggaccggcccaagcggacacgtacatccttcactgccgagcagctgtaccgcctggagatggagttccagcgctgccagtatgtggtgggccgcgagcgcactgagctggcccgccagctgaacctctccgagacccaggtgaaggtctggttccagaaccgccgcaccaagcagaagaaagaccagagcagagacctggagaagcgggcgtcctcctcagcctccgaggcctttgccacctccaacattctgcggctgctggagcagggccggctgctctctgtgcccagggcccctagcctcctggcgctgacccctagcctgccaggcctacctgccagccacaggggcacctccttaggtgaccccaggaactcctccccacgcctcaacccgctgtcctcggcctcagcgtcccccccactgccgccccctctgccagctgtctgcttttcctcggccccgctcctggatctgcctgccggctacgaactgggttcctcggccttcgagccatacagctggctagaacggaaagtgggcagcgccagcagctgcaagaaagctaacacttaagactcccaccctgtgacactgagtcccgagcacagcaccttcccagtctcctgtgccccagcggacagcactgagcaggccccggagaggaggggctgcagccacacactcttccccacctgccccccagctcagagactcgtgaccaaatggccttggtcccgcagcttgtgtgcgtgagtgcagtgtgagtgtgtgtgtctctcactgaaataaaaggaaaacaatgacaagaagggaaaaaaaaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:25806 -> Molecular function: GO:0000976 [transcription regulatory region sequence-specific DNA binding] evidence: IEA
            GeneID:25806 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:25806 -> Molecular function: GO:0031490 [chromatin DNA binding] evidence: IEA
            GeneID:25806 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:25806 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:25806 -> Biological process: GO:0007398 [ectoderm development] evidence: TAS
            GeneID:25806 -> Biological process: GO:0007409 [axonogenesis] evidence: IEA
            GeneID:25806 -> Biological process: GO:0007601 [visual perception] evidence: TAS
            GeneID:25806 -> Biological process: GO:0009950 [dorsal/ventral axis specification] evidence: IEA
            GeneID:25806 -> Biological process: GO:0016055 [Wnt receptor signaling pathway] evidence: IEA
            GeneID:25806 -> Biological process: GO:0030900 [forebrain development] evidence: ISS
            GeneID:25806 -> Biological process: GO:0048048 [embryonic eye morphogenesis] evidence: IEA
            GeneID:25806 -> Biological process: GO:0060041 [retina development in camera-type eye] evidence: IEA
            GeneID:25806 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
            GeneID:25806 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA