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2025-05-09 20:06:12, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_007222 5139 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens zinc fingers and homeoboxes 1 (ZHX1), transcript variant 2, mRNA. ACCESSION NM_007222 VERSION NM_007222.4 GI:323510646 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 5139) AUTHORS Bird,L.E., Ren,J., Nettleship,J.E., Folkers,G.E., Owens,R.J. and Stammers,D.K. TITLE Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains JOURNAL BMC Struct. Biol. 10, 13 (2010) PUBMED 20509910 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5139) AUTHORS Wienk,H., Lammers,I., Hotze,A., Wu,J., Wechselberger,R.W., Owens,R., Stammers,D.K., Stuart,D., Kaptein,R. and Folkers,G.E. TITLE The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension JOURNAL Biochemistry 48 (21), 4431-4439 (2009) PUBMED 19348505 REMARK GeneRIF: structure of the tandem zinc-finger region of human ZHX1 REFERENCE 3 (bases 1 to 5139) AUTHORS Kim,S.H., Park,J., Choi,M.C., Kim,H.P., Park,J.H., Jung,Y., Lee,J.H., Oh,D.Y., Im,S.A., Bang,Y.J. and Kim,T.Y. TITLE Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression JOURNAL Biochem. Biophys. Res. Commun. 355 (2), 318-323 (2007) PUBMED 17303076 REMARK GeneRIF: ZHX1 enhanced the transcriptional repression mediated by DNMT3B when DNMT3B is directly targeted to DNA. These results showed for the first the direct linkage between DNMT and zinc-fingers homeoboxes protein, leading to enhanced gene silencing by DNMT3B REFERENCE 4 (bases 1 to 5139) AUTHORS Ogata-Kawata,H., Yamada,K., Uesaka-Yoshino,M., Kagawa,N. and Miyamoto,K. TITLE BS69, a corepressor interacting with ZHX1, is a bifunctional transcription factor JOURNAL Front. Biosci. 12, 1911-1926 (2007) PUBMED 17127430 REMARK Publication Status: Online-Only REFERENCE 5 (bases 1 to 5139) AUTHORS Liu,G., Clement,L.C., Kanwar,Y.S., Avila-Casado,C. and Chugh,S.S. TITLE ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome JOURNAL J. Biol. Chem. 281 (51), 39681-39692 (2006) PUBMED 17056598 REMARK GeneRIF: ZHX proteins 1, 2 and 3 are major transcriptional mediators of podocyte disease Erratum:[J Biol Chem. 2007 Apr 27;282(17):13140] REFERENCE 6 (bases 1 to 5139) AUTHORS Yamada,K., Kawata,H., Shou,Z., Hirano,S., Mizutani,T., Yazawa,T., Sekiguchi,T., Yoshino,M., Kajitani,T. and Miyamoto,K. TITLE Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3 JOURNAL Biochem. J. 373 (PT 1), 167-178 (2003) PUBMED 12659632 REMARK GeneRIF: a search of ZHX1-interacting proteins using a yeast two-hybrid system REFERENCE 7 (bases 1 to 5139) AUTHORS Yamada,K., Kawata,H., Matsuura,K., Shou,Z., Hirano,S., Mizutani,T., Yazawa,T., Yoshino,M., Sekiguchi,T., Kajitani,T. and Miyamoto,K. TITLE Functional analysis and the molecular dissection of zinc-fingers and homeoboxes 1 (ZHX1) JOURNAL Biochem. Biophys. Res. Commun. 297 (2), 368-374 (2002) PUBMED 12237128 REMARK GeneRIF: This study characterized features of ZHX-1 involved in nuclear localization, dimerization, and transcriptional activity, and mapped these domains. REFERENCE 8 (bases 1 to 5139) AUTHORS Hirano,S., Yamada,K., Kawata,H., Shou,Z., Mizutani,T., Yazawa,T., Kajitani,T., Sekiguchi,T., Yoshino,M., Shigematsu,Y., Mayumi,M. and Miyamoto,K. TITLE Rat zinc-fingers and homeoboxes 1 (ZHX1), a nuclear factor-YA-interacting nuclear protein, forms a homodimer JOURNAL Gene 290 (1-2), 107-114 (2002) PUBMED 12062805 REFERENCE 9 (bases 1 to 5139) AUTHORS Yamada,K., Osawa,H. and Granner,D.K. TITLE Identification of proteins that interact with NF-YA JOURNAL FEBS Lett. 460 (1), 41-45 (1999) PUBMED 10571058 REFERENCE 10 (bases 1 to 5139) AUTHORS Yamada,K., Printz,R.L., Osawa,H. and Granner,D.K. TITLE Human ZHX1: cloning, chromosomal location, and interaction with transcription factor NF-Y JOURNAL Biochem. Biophys. Res. Commun. 261 (3), 614-621 (1999) PUBMED 10441475 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA238313.1, AF195766.1, CA776642.1, BC040481.1 and AK025236.1. On Feb 17, 2011 this sequence version replaced gi:63079679. Summary: The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene. [provided by RefSeq, Feb 2011]. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040481.1, AF195766.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025081, ERS025082 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-237 DA238313.1 1-237 238-3713 AF195766.1 1-3476 3714-4172 CA776642.1 136-594 4173-5093 BC040481.1 3994-4914 5094-5139 AK025236.1 2584-2629 FEATURES Location/Qualifiers source 1..5139 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="8" /map="8q24.13" gene 1..5139 /gene="ZHX1" /note="zinc fingers and homeoboxes 1" /db_xref="GeneID:11244" /db_xref="HGNC:12871" /db_xref="MIM:604764" exon 1..271 /gene="ZHX1" /inference="alignment:Splign:1.39.8" exon 272..385 /gene="ZHX1" /inference="alignment:Splign:1.39.8" exon 386..3235 /gene="ZHX1" /inference="alignment:Splign:1.39.8" misc_feature 587..589 /gene="ZHX1" /note="upstream in-frame stop codon" variation 601 /gene="ZHX1" /replace="c" /replace="t" /db_xref="dbSNP:16898197" CDS 611..3232 /gene="ZHX1" /note="zinc fingers and homeobox 1; zinc finger and homeodomain protein 1" /codon_start=1 /product="zinc fingers and homeoboxes protein 1" /protein_id="NP_009153.3" /db_xref="GI:63079680" /db_xref="CCDS:CCDS6342.1" /db_xref="GeneID:11244" /db_xref="HGNC:12871" /db_xref="MIM:604764" /translation="
MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENTRAESISSDEEVHESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENAEQAESTEVSSSGISISKTPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASESNTSTSIVNRIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSTTIIIDSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSPADESGAPKSGSTGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPRGSKRINNWDRGPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVREWFAERQRRSELGIELFEENEEEDEVIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD
"
misc_feature 743..745
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UKY1.1); phosphorylation site"
misc_feature 749..751
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UKY1.1); phosphorylation site"
misc_feature 752..754
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UKY1.1); phosphorylation site"
misc_feature 1424..2302
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
Region: Required for interaction with NFYA"
misc_feature 1424..1906
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
Region: Required for dimerization"
misc_feature 1475..1477
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature <1517..1639
/gene="ZHX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature 1517..1519
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature order(1532..1534,1550..1552,1589..1591,1595..1600,
1607..1612,1616..1624,1628..1633)
/gene="ZHX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(1598..1600,1607..1612,1619..1621)
/gene="ZHX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 2012..2179
/gene="ZHX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(2012..2017,2021..2023,2072..2074,2090..2092,
2129..2131,2135..2140,2147..2152,2156..2164,2168..2173)
/gene="ZHX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(2018..2020,2138..2140,2147..2152,2159..2161)
/gene="ZHX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 2315..>2458
/gene="ZHX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(2315..2329,2333..2335,2384..2386,2402..2404,
2441..2443,2447..2452)
/gene="ZHX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(2321..2323,2330..2332,2450..2452)
/gene="ZHX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 2552..2554
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q9UKY1.1); phosphorylation site"
misc_feature 2552..2554
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2603..2761
/gene="ZHX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(2603..2605,2609..2611,2660..2662,2678..2680,
2717..2719,2723..2728,2735..2740,2744..2752,2756..2761)
/gene="ZHX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(2606..2608,2726..2728,2735..2740,2747..2749)
/gene="ZHX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 2654..2656
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2810..2914
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
Region: Required for nuclear localization"
misc_feature 2954..3085
/gene="ZHX1"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(2990..2992,3008..3010,3047..3049,3053..3058,
3065..3070,3074..3082)
/gene="ZHX1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(3056..3058,3065..3070,3077..3079)
/gene="ZHX1"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
misc_feature 3101..3229
/gene="ZHX1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9UKY1.1);
Region: Required for repressor activity"
STS 646..784
/gene="ZHX1"
/standard_name="WI-11363"
/db_xref="UniSTS:69740"
exon 3236..5106
/gene="ZHX1"
/inference="alignment:Splign:1.39.8"
STS 3413..3662
/gene="ZHX1"
/standard_name="STS-T66784"
/db_xref="UniSTS:55045"
variation 3718..3719
/gene="ZHX1"
/replace="a"
/replace="c"
/db_xref="dbSNP:1966863"
STS 3779..3927
/gene="ZHX1"
/standard_name="D8S1558"
/db_xref="UniSTS:153699"
STS 3786..3910
/gene="ZHX1"
/standard_name="G30158"
/db_xref="UniSTS:61217"
STS 4498..4732
/gene="ZHX1"
/standard_name="STS-D60292"
/db_xref="UniSTS:50610"
STS 4537..4726
/gene="ZHX1"
/standard_name="RH78355"
/db_xref="UniSTS:71683"
polyA_signal 4789..4794
/gene="ZHX1"
variation 4810
/gene="ZHX1"
/replace="a"
/replace="c"
/db_xref="dbSNP:1869248"
polyA_site 4813
/gene="ZHX1"
polyA_signal 5076..5081
/gene="ZHX1"
polyA_site 5106
/gene="ZHX1"
ORIGIN
gacgcgcgcgcgggagggccccgccttggccggctctctcccttccccctccgcccccggacggccgctggggcgcgcgcctctcctcgcacccccaccctgagtccccacactccgcggggccaccgagctgctgaggcccctttgcgggcccgccgagcggttccgggtttagggttcacaggtcagagttgactccctgaaaagtgcagccggtttgaaatgcaagatggcggcggcgtggcgctgagaggcgcggcggcccctgcaggagaagacagactgctgctttggacctgttggtaatgatggcctgagctaaacatctaactagaagggatacccttccatttcaaagaacagaatgctaaggaagctgtggcaagtgattggagttgtgcttcaaaaatttcagaaattcagcagtattttatctgccaacaataagctctttacttgattgcaccatgagaaagctgctaatgagacttgttgagcacaaaaatggacttgaagaaccaaaagccattgttttcaaatgaagaacactgaacagttttaagcctcgatgctttttaatcaccactgagcttttcctcataacatcagaatggcaagcaggcgaaaatcaacaacaccttgcatggtccttgccagtgaacaagatccagaccttgagttgatatcagatttggatgaaggtcctcctgtgcttacacctgtagaaaacaccagagcagagagtatctcaagtgatgaagaggttcatgaatctgtggattcagacaatcagcaaaataaaaaagttgaaggtggatatgaatgtaaatattgtacttttcaaactccagatctaaatatgtttacttttcatgtggattcggaacatcccaatgtagtgctaaattcatcctatgtttgtgtcgaatgcaattttcttaccaaaaggtatgatgcactttctgagcataatctgaaatatcacccaggagaagagaattttaagttgactatggtgaaacgtaataaccagacaatctttgaacaaacaataaatgatctgacttttgatggtagttttgttaaagaggagaatgcagagcaagcagaatctacagaagtttcttcttcgggaatatctatcagtaaaactcctatcatgaaaatgatgaaaaataaagtggaaaataaacggattgcagttcatcataactcagttgaggacgttcctgaagagaaagagaatgaaatcaaaccagaccgtgaagaaattgtagaaaatccaagttcttcagcttctgaatctaatacaagtacttccattgtaaacagaatacatccaagtactgccagcacggtagtgacaccagcagcagttcttcctggattggcacaggtgataactgctgtatctgctcagcagaattctaatttgattcccaaagtcttaatccctgttaatagcattcccacctacaatgctgcattggataacaatccccttttacttaacacctacaacaagttcccttacccaacaatgtcagaaattacagttctttctgctcaagcaaaatatacagaggaacagatcaagatatggttttcagcccaacgtttaaaacatggtgttagttggactcccgaggaagtagaggaggcaagaaggaaacaattcaatggaacagtgcatactgtacctcagaccataactgttattcctacacacatttccacagggagtaatggtttaccatctattttacagacatgccaaatagttggtcagcctggtctggtccttactcaagtggctggaacaaacaccttgccagttacagcacctatagccttgacagtggcaggcgttccaagtcaaaataatatacagaaaagtcaggtacctgctgctcagcctactgcagaaacaaagccagcaacagcagcagttccaacttctcaaagtgtcaaacatgaaactgcattggtaaaccctgattcatttggcattcgggcaaaaaagacaaaagagcaactggcagaattaaaagttagctaccttaaaaatcagtttccccatgattcagaaattatcagacttatgaaaataacaggcctgacgaaaggagagattaaaaaatggtttagtgacacaaggtacaaccagagaaattcaaagagtaatcagtgcttacatctcaacaatgattcctctaccaccattattatagactccagtgatgaaaccacggaatccccaactgttggtactgcacagcctaagcaatcctggaatccttttcctgactttactccccaaaagtttaaagagaaaactgcagagcagcttcgtgtccttcaggcaagttttctcaacagctctgtacttacagatgaagaattaaataggttaagggcacaaaccaaacttaccagaagagaaatcgatgcttggtttacagagaagaagaaatcaaaagctttaaaggaagagaaaatggaaatagatgaaagtaatgcaggtagttccaaagaagaagctggagaaacttctcctgcagatgaatctggtgcacctaagtcagggagtacaggcaagatatgtaaaaaaacacctgagcagctgcacatgcttaagagtgcatttgtccggacacagtggccatcaccagaagagtatgacaagttggccaaagaaagcgggcttgctagaacagacatagttagttggtttggggacacccgttatgcttggaagaatggaaacttgaaatggtactactactatcagagcgccaattcaagtagtatgaatggtctgtcttcccttaggaaaagagggagagggagacccaaaggacggggaagaggaagaccgcgtgggcggcctagaggaagcaaaagaattaacaactgggacaggggaccatcactcataaaatttaaaactggaactgcaatacttaaggattattacctgaagcacaagtttcttaatgagcaagaccttgatgaacttgttaacaaatcacatatgggctatgagcaggtcagagagtggtttgcagaaagacagagaagatcagaattaggtatagaattatttgaggaaaatgaggaggaagatgaagttattgatgaccaggaagaggatgaagaagaaacagatgatagtgacacttgggaacctccacgacatgtgaaacggaagctgtctaaatcagatgactgaaatctgcctaaaacgttgaaggagaatcaattcttcaactcaagatgtctgatttactgtgaatttgcccaatctttgatgacattgaaaacgttttggggcatacacactcaaaaagcaggatccaatacccaaaagaaatggaacttaatgttgtgccaaagttaaactactgcagttggtggaagttctgcaatgtaaatagaacactaattaaaaaacaacttgtaaaaatgcaatttaaattttaatacagtacatttttcttctaatatgatggagacattctgaatcttagactttctgagggggtttaatgaccactagagcttgtcctcatattcagtccagtttaatactgtatgtctagtaagatgggctatatattgcctctattctttgagatgtgattaagcttagaactttgaccaaaaattttacagtaaaaattgttagaaatgggtaaaaaaaaaaaaaaaaaaaaaaccctgatttattactatgtcttatttatcagaccctgcactaagattaaaagttgtgcatgggcttatacaatttcaaatgtaaaaacagcctatttatatatgttgaaacaataagattttatggtttcactggcccttaataattggatccttcattaaacacatccatgaataccactgtttctactgttacttgttccattagaagctgatttgctttttattaaactgcaggaaattaattctgaagaaggaaaagaaactgacatggtaatttggatagggtgaagctttgaaataaatactgcaccaaaaatgtgaaaaagaatcacgtagtaaatgtatacttagtgttttcttacaatcgtggaaatcagaaatgtttatacaggtgtcagatcagaatttttaagagttatctttcagtgaaattttataacagtttcagtgaatagagaaaaaattctgaactgatcataatgagttaaaagttagcttttcacttatgaatcatgggagtgttaactgttaactcttgccgtatcaggagactgaaagttcatactaatttacaaactttgtaaagactggtgctgttcattcatattgggaagaaccctttcttttgtgaccataggaccatttttcaaaatgcgctttcttcgtagaagaaatgttcagtttaattagctttggattttaacatgtttttctgaatgaccagatgtaggcttagccagtttattttctctaatttaatggataataaatattaagctcttggttaaatgtttttcagccattgaaaatgttatgaaaaagccttgaatatgcatgctgctttcatttttataaactttttattttttaactatagctttattagtaattccaaaatgctgcaatgtagctgatttcctcactcagacagctggctttgtgggtggcttttttcatactactgttaacttttttaaaaaagaagcaatgtaaagaccgtaatgcactaagctttttttttttcttttacacgtttaaaaacttcttaaagcactctgtaatataatgattaaattgctcccttttataaacattgctaatgtggtctgagttttgtttgacaataattttaatgttctcaaaatttgaaatgtcaagtattagaaatgaagcctttgaatatagttgtttcccttgcaatatgttaactctgtgtagctgtatataactattaatttccctcatctcttttataggcctgataaaactcttctctgacgtttgctagcttttaaatatatttatttgacagagcaaaagaaccctcttctggttgattgtgaccttgaatacaaaataaaagtagtgattagtagtttacagtgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:11244 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:11244 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: IDA
GeneID:11244 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:11244 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
GeneID:11244 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:11244 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IDA
GeneID:11244 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:11244 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:11244 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
GeneID:11244 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IDA
GeneID:11244 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
by
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