GGRNA | NM_001202545.1

LOCUS       NM_001202545            2901 bp    mRNA    linear   PRI 12-MAY-2013
DEFINITION  Homo sapiens cut-like homeobox 1 (CUX1), transcript variant 6,
            mRNA.
ACCESSION   NM_001202545 XR_108855 XR_110720 XR_113043 XR_114073
VERSION     NM_001202545.1  GI:321400113
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2901)
  AUTHORS   Li,T., Wang,H., Sun,Y., Zhao,L., Gang,Y., Guo,X., Huang,R.,
            Yang,Z., Pan,Y., Wu,K., Xu,L., Liu,Z. and Fan,D.
  TITLE     Transcription factor CUTL1 is a negative regulator of drug
            resistance in gastric cancer
  JOURNAL   J. Biol. Chem. 288 (6), 4135-4147 (2013)
   PUBMED   23255599
  REMARK    GeneRIF: overexpression of active CUTL1 significantly resulted in
            increased cancer tissue response to chemotherapy and therefore
            inhibited growth, whereas knockdown of CUTL1 conferred resistance
            to chemotherapy.
REFERENCE   2  (bases 1 to 2901)
  AUTHORS   McNerney,M.E., Brown,C.D., Wang,X., Bartom,E.T., Karmakar,S.,
            Bandlamudi,C., Yu,S., Ko,J., Sandall,B.P., Stricker,T.,
            Anastasi,J., Grossman,R.L., Cunningham,J.M., Le Beau,M.M. and
            White,K.P.
  TITLE     CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7
            frequently inactivated in acute myeloid leukemia
  JOURNAL   Blood 121 (6), 975-983 (2013)
   PUBMED   23212519
  REMARK    GeneRIF: Data indicate CUX1 as a conserved, haploinsufficient tumor
            suppressor frequently deleted in myeloid neoplasms.
REFERENCE   3  (bases 1 to 2901)
  AUTHORS   Liu,K.C., Lin,B.S., Zhao,M., Wang,K.Y. and Lan,X.P.
  TITLE     Cutl1: a potential target for cancer therapy
  JOURNAL   Cell. Signal. 25 (1), 349-354 (2013)
   PUBMED   23085261
  REMARK    GeneRIF: Cutl1 played transcriptional level mediated by signal
            transduction, translational level mediated by miR122,
            posttranslational level such as phosphorylation,
            de-phosphorylation, acetylation and proteolytic cleavage.
            Review article
REFERENCE   4  (bases 1 to 2901)
  AUTHORS   Sasayama,D., Hiraishi,A., Tatsumi,M., Kamijima,K., Ikeda,M.,
            Umene-Nakano,W., Yoshimura,R., Nakamura,J., Iwata,N. and Kunugi,H.
  TITLE     Possible association of CUX1 gene polymorphisms with antidepressant
            response in major depressive disorder
  JOURNAL   Pharmacogenomics J. (2012) In press
   PUBMED   22584459
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   5  (bases 1 to 2901)
  AUTHORS   Zhai,Z., Ha,N., Papagiannouli,F., Hamacher-Brady,A., Brady,N.,
            Sorge,S., Bezdan,D. and Lohmann,I.
  TITLE     Antagonistic regulation of apoptosis and differentiation by the Cut
            transcription factor represents a tumor-suppressing mechanism in
            Drosophila
  JOURNAL   PLoS Genet. 8 (3), E1002582 (2012)
   PUBMED   22438831
  REMARK    GeneRIF: we find repression of apoptosis regulators by Cux1 in
            human cancer cells.
REFERENCE   6  (bases 1 to 2901)
  AUTHORS   Lievens,P.M., Tufarelli,C., Donady,J.J., Stagg,A. and Neufeld,E.J.
  TITLE     CASP, a novel, highly conserved alternative-splicing product of the
            CDP/cut/cux gene, lacks cut-repeat and homeo DNA-binding domains,
            and interacts with full-length CDP in vitro
  JOURNAL   Gene 197 (1-2), 73-81 (1997)
   PUBMED   9332351
REFERENCE   7  (bases 1 to 2901)
  AUTHORS   Chernousov,M.A., Stahl,R.C. and Carey,D.J.
  TITLE     Schwann cells secrete a novel collagen-like adhesive protein that
            binds N-syndecan
  JOURNAL   J. Biol. Chem. 271 (23), 13844-13853 (1996)
   PUBMED   8662884
REFERENCE   8  (bases 1 to 2901)
  AUTHORS   Scherer,S.W., Neufeld,E.J., Lievens,P.M., Orkin,S.H., Kim,J. and
            Tsui,L.C.
  TITLE     Regional localization of the CCAAT displacement protein gene
            (CUTL1) to 7q22 by analysis of somatic cell hybrids
  JOURNAL   Genomics 15 (3), 695-696 (1993)
   PUBMED   8468066
REFERENCE   9  (bases 1 to 2901)
  AUTHORS   Neufeld,E.J., Skalnik,D.G., Lievens,P.M. and Orkin,S.H.
  TITLE     Human CCAAT displacement protein is homologous to the Drosophila
            homeoprotein, cut
  JOURNAL   Nat. Genet. 1 (1), 50-55 (1992)
   PUBMED   1301999
REFERENCE   10 (bases 1 to 2901)
  AUTHORS   Ottolenghi,S., Mantovani,R., Nicolis,S., Ronchi,A. and Giglioni,B.
  TITLE     DNA sequences regulating human globin gene transcription in
            nondeletional hereditary persistence of fetal hemoglobin
  JOURNAL   Hemoglobin 13 (6), 523-541 (1989)
   PUBMED   2481658
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC410774.1, AK122726.1,
            L12579.1 and BC012323.1.
            On or before Aug 3, 2011 this sequence version replaced
            gi:310128672, gi:310120056, gi:310118377, gi:310115312.
            
            Summary: The protein encoded by this gene is a member of the
            homeodomain family of DNA binding proteins. It may regulate gene
            expression, morphogenesis, and differentiation and it may also play
            a role in the cell cycle progession. Several alternatively spliced
            transcript variants encoding different isoforms have been
            identified.[provided by RefSeq, Feb 2011].
            
            Transcript Variant: This variant (6) lacks an in-frame exon in the
            5' region and has an alternate 3' sequence including the coding
            region, as compared to variant 1. The resulting isoform (f) lacks
            an internal segment and has a shorter and distinct C-terminus, as
            compared to isoform d.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122726.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               DC410774.1         1-117
            118-455             AK122726.1         1-338
            456-1957            L12579.1           486-1987
            1958-2901           BC012323.1         1983-2926
FEATURES             Location/Qualifiers
     source          1..2901
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..2901
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /note="cut-like homeobox 1"
                     /db_xref="GeneID:1523"
                     /db_xref="HGNC:2557"
                     /db_xref="MIM:116896"
     exon            1..190
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    74..76
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /note="upstream in-frame stop codon"
     variation       80
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373949747"
     variation       97
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:368174106"
     variation       101
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371287227"
     variation       110
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373609751"
     CDS             128..2026
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /note="isoform f is encoded by transcript variant 6; golgi
                     integral membrane protein 6; protein CASP; cut homolog;
                     putative protein product of Nbla10317; homeobox protein
                     cux-1; CCAAT displacement protein"
                     /codon_start=1
                     /product="protein CASP isoform f"
                     /protein_id="NP_001189474.1"
                     /db_xref="GI:321400114"
                     /db_xref="CCDS:CCDS56499.1"
                     /db_xref="GeneID:1523"
                     /db_xref="HGNC:2557"
                     /db_xref="MIM:116896"
                     /translation="

MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQDESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQGEIDALSKRSKEAEAAFLNVYKRLIDVPEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGRCAELQVRITEAVATATEQRELIARLEQDLSIIQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGPAAPASGALPEGQVDSLLSIISSQRERFRARNQELEAENRLAQHTLQALQSELDSLRADNIKLFEKIKFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRKYLSLSPWDKATLSMGRLVLSNKMARTIGFFYTLFLHCLVFLVLYKLAWSESMERDCATFCAKKFADHLHKFHENDNGAAAGDLWQ

"
     misc_feature    1250..1930
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /note="CASP C terminal; Region: CASP_C; pfam08172"
                     /db_xref="CDD:203868"
     variation       152
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200925347"
     exon            191..301
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       193
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:140709702"
     variation       208
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376836450"
     variation       223
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150487622"
     variation       258
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200309302"
     variation       265
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145317607"
     variation       294
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149191757"
     exon            302..349
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       321
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143267032"
     variation       322
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374397164"
     exon            350..428
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       408
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367586602"
     variation       422
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148322402"
     exon            429..552
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       436
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143157780"
     variation       451
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201650660"
     variation       493
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375357960"
     variation       494
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138328289"
     variation       499
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11540900"
     variation       506
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199800281"
     exon            553..629
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       563
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142863665"
     variation       565
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201993734"
     variation       610
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199535463"
     variation       620
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150799140"
     exon            630..696
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       635
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:75508780"
     variation       645
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187519642"
     variation       662
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139126094"
     variation       676
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149507748"
     exon            697..745
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       723
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372003626"
     exon            746..850
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       757
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377269248"
     variation       793
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370842930"
     variation       795
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189334175"
     variation       799
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:180828525"
     STS             800..902
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /standard_name="D12S1228E"
                     /db_xref="UniSTS:151475"
     variation       804
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139855321"
     variation       847
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143307709"
     exon            851..1039
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       860
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200126349"
     variation       884
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372334618"
     variation       901
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139114802"
     variation       911
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376319241"
     variation       938
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142950109"
     variation       957
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369666651"
     variation       963
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367848953"
     variation       982
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151118398"
     variation       1019
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201709857"
     variation       1033
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374020928"
     exon            1040..1098
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     exon            1099..1147
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1125
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141118279"
     variation       1126
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11540899"
     exon            1148..1244
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1153
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147937477"
     variation       1195
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369005585"
     variation       1215
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374021528"
     variation       1216
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367577378"
     variation       1220
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371301313"
     exon            1245..1372
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1254
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:62001055"
     variation       1255
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:813000"
     variation       1269
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372464298"
     variation       1289
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:114381819"
     variation       1293
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139906438"
     variation       1297
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:149786604"
     variation       1310
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371828253"
     variation       1315
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200271633"
     variation       1319
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145765083"
     variation       1320
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375278390"
     variation       1369
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370845468"
     exon            1373..1439
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1379
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:803064"
     variation       1380
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368235304"
     variation       1388
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144199298"
     variation       1389
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:146554363"
     variation       1419
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199558313"
     variation       1425
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140386892"
     exon            1440..1552
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1459
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199776060"
     variation       1460
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150976222"
     variation       1465
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140831161"
     variation       1474
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371715592"
     variation       1490
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375776301"
     variation       1527
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150151598"
     variation       1542
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2230102"
     variation       1552
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199822336"
     exon            1553..1669
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1562
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138450169"
     variation       1567
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369806479"
     variation       1583
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142767232"
     variation       1615
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146927122"
     variation       1622
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2230103"
     variation       1625
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:118010189"
     variation       1648
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373393100"
     variation       1667
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144393643"
     variation       1668
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148760130"
     exon            1670..1753
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1676
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187131238"
     variation       1689
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370290068"
     variation       1690
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375513246"
     variation       1697
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141515782"
     variation       1698
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202149844"
     variation       1704
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150890071"
     variation       1714
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111537304"
     variation       1715
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139293638"
     variation       1720
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144329021"
     variation       1721
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146049827"
     variation       1751
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371285615"
     variation       1752
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140034854"
     exon            1754..1810
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1764
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1293839"
     variation       1798
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372229678"
     exon            1811..1891
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1815
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144124584"
     variation       1841
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372479780"
     STS             1842..1926
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /standard_name="MARC_4357-4358:991938494:5"
                     /db_xref="UniSTS:231083"
     variation       1842
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145083539"
     variation       1850
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201615556"
     exon            1892..1956
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1901
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367747037"
     variation       1906
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149124693"
     variation       1915
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200899513"
     variation       1916
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142155041"
     variation       1918
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151204833"
     exon            1957..2894
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /inference="alignment:Splign:1.39.8"
     variation       1960
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141196267"
     variation       1961
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376508181"
     variation       1984
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200345816"
     variation       1985
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377645698"
     variation       1997
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369144524"
     variation       2011
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112505360"
     variation       2022..2023
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:146386435"
     variation       2044
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199575958"
     variation       2045
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373876353"
     variation       2051
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:909128"
     variation       2055
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201628239"
     variation       2056
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377408845"
     variation       2062
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374386627"
     variation       2082
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1296069"
     variation       2139
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151048012"
     variation       2165
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141097964"
     variation       2199
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150278456"
     variation       2237
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2734615"
     variation       2245
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185803208"
     variation       2258
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75580662"
     variation       2276
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191591974"
     variation       2304
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41275221"
     variation       2373
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182997186"
     variation       2432
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113634317"
     variation       2433
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188776036"
     variation       2461
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147926104"
     variation       2536
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:77369840"
     STS             2630..2892
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /standard_name="WI-21075"
                     /db_xref="UniSTS:50237"
     variation       2631
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192033664"
     STS             2736..2893
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /standard_name="RH44454"
                     /db_xref="UniSTS:53362"
     variation       2743
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:8950"
     variation       2752
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1056363"
     variation       2753
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141716299"
     variation       2769
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:182766749"
     variation       2775
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:75104200"
     variation       2804
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1056386"
     variation       2830
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:9691899"
     polyA_signal    2874..2879
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
     variation       2892
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73187873"
     polyA_site      2894
                     /gene="CUX1"
                     /gene_synonym="CASP; CDP; CDP/Cut; CDP1; Clox; COY1;
                     CUTL1; CUX; Cux/CDP; GOLIM6; Nbla10317; p100; p110; p200;
                     p75"
ORIGIN

ctcggtggcggcggcggcggccggctccaggccgggttttggcgccgcccgcctgctgcctcctggcggctcctgaactccagccccctctctatcagccgctcactccgtctcaatatgtctcaagatggcggccaatgtgggatcgatgtttcaatattggaagcgctttgatttacagcagctgcagagagaactcgatgccaccgcaacggtattggcgaaccggcaggatgaaagtgagcagtccagaaagcggcttatcgaacagagccgggagttcaagaagaacactccagaggatttgcgcaagcaggtagcgccgctgctgaagagtttccaaggagagattgatgcactgagtaaaagaagcaaggaagctgaagcagctttcttgaatgtctacaaaagattgattgacgtcccagaggttacgataaaagcacttaaagagaaaatccgagaatatgaacagacactgaagaaccaagccgaaaccatagctcttgagaaggaacagaagttacagaatgactttgcagaaaaggagagaaagctgcaggagacacagatgtccaccacctcaaagctggaggaagctgagcataaggttcagagcctacaaacagccctggaaaaaactcgaacagaattatttgacctgaaaaccaaatacgatgaagaaactactgcaaaggccgacgagattgaaatgatcatgacggaccttgaaagggcaaaccagagggcagaggtggctcagagagaggcggagaccttaagggaacagctctcatcggccaatcactccctccagctggcctcacagatccagaaggcaccagacgtggagcaggccatagaggtgctgacccgctccagcctagaagttgagttggccgccaaggagcgggagatcgcacagctggtggaggacgtgcagagactccaggccagcctcaccaagctgcgggagaattcggccagccagatctcacagcttgagcagcagctgagcgccaaaaacagcacactcaaacaactggaagaaaaactcaaaggccaggctgactatgaagaggtgaagaaagagctgaacattctgaagtccatggagtttgcaccgtccgagggcgctgggacacaggatgcggccaagcccctggaggtgctgttgctggagaagaaccgctcgctgcagtccgagaacgccgcgctgcgcatctccaacagcgacctgagcggacgctgtgcagagctgcaagtccgtatcactgaggctgtggccacagccactgagcagagagagctgatcgcccgcctggagcaggacctgagcatcattcagtccatccagcggcccgatgccgagggtgccgctgagcaccgcctggagaagatcccagagcccatcaaagaggccactgccctattctacggacctgcagcaccagccagcggtgccctcccagagggccaggtggattcactgctttccatcatctccagccagagggagcgcttccgtgcccggaaccaggagcttgaggccgagaaccgcctggcccagcacaccctccaggccctgcagagtgagctggacagcctgcgcgccgacaacatcaagctctttgagaagatcaagttcctgcagagctaccctggccggggcagcggcagtgatgacacggagctgcggtactcgtcccagtacgaggagcgcctggaccccttctcctccttcagcaagcgggagcggcagaggaagtacctgagcttgagtccctgggacaaggccaccctcagcatggggcgtctggttctctccaacaagatggcgcgcaccatcggcttcttctacacactgttcctgcactgcctggtcttcctggtgctctacaagctggcatggagcgagagcatggagagggactgtgccaccttctgcgccaagaagttcgctgaccacctgcacaagttccacgagaatgacaacggggctgcggctggtgacttgtggcagtgataccccggggcctcccccgtgacagtgacggctgcgcctccaccccgactgctcagtgcatctaatcacttagactcccctgaagaatcccccatggaaactgcccttatccgctgtccagcagctgccagaggccccaggtcacctcgggtccccttgaaagaatgtctcggtcacatcaggcccgctaggtccagagagcgagcccccaatgcccggccaggctaagccgcagagaccctctcagcccccacctcaggttagggctctgcccgcagcctgacctctagccctggtggcagaggtccctcagctgcgaggctaattgggtgaccaccgattccagctgcggttaatccagcttgggcctgtctgcactgcgatcctcttgggctctcctaggatccccccatgccccgtaagaggtggaagacgcttccttccaggacagcaggctttgagtccagcacccccagcctgcctttgccaccagccccaccctgcagagtatatgaggcttgacagagtctgccccctcccccactgcaccccaagagagagagccccagccagcggaacagtttctattaccccctccctgcccccagacccatgtgatttctgctttcttctttagcaagatattctggtttctagataaggaagagtctctaatgagcccccgagccccagtctcttcagactcatggattggtctgaggggtctgaacgtctcctagccaatcagaactggctgtggaccaccctagcacggccacctctcagggccactggcaggccttcctgagttagatttgtagttgcatatttagctttgcacatttgaaataaaccacggttgcagccaaaaaaaa

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