LOCUS       NM_001195470            5652 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens SATB homeobox 1 (SATB1), transcript variant 3, mRNA.
ACCESSION   NM_001195470
VERSION     NM_001195470.1  GI:306518683
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5652)
  AUTHORS   Zhang,J., Zhang,B., Zhang,X., Sun,Y., Wei,X., McNutt,M.A., Lu,S.,
            Liu,Y., Zhang,D., Wang,M., Lin,Z. and Niu,N.
  TITLE     SATB1 expression is associated with biologic behavior in colorectal
            carcinoma in vitro and in vivo
  JOURNAL   PLoS ONE 8 (1), E47902 (2013)
   PUBMED   23326301
  REMARK    GeneRIF: Findings suggest that SATB1 (Special AT-rich
            sequence-binding protein 1)is involved in the carcinogenesis,
            development and progression of colorectal cancer.
REFERENCE   2  (bases 1 to 5652)
  AUTHORS   Shukla,S., Sharma,H., Abbas,A., MacLennan,G.T., Fu,P.,
            Danielpour,D. and Gupta,S.
  TITLE     Upregulation of SATB1 is associated with prostate cancer
            aggressiveness and disease progression
  JOURNAL   PLoS ONE 8 (1), E53527 (2013)
   PUBMED   23308245
  REMARK    GeneRIF: SATB1 has ability to promote prostate cancer
            aggressiveness through epithelial-mesenchymal transition.
REFERENCE   3  (bases 1 to 5652)
  AUTHORS   Ordinario,E., Han,H.J., Furuta,S., Heiser,L.M., Jakkula,L.R.,
            Rodier,F., Spellman,P.T., Campisi,J., Gray,J.W., Bissell,M.J.,
            Kohwi,Y. and Kohwi-Shigematsu,T.
  TITLE     ATM suppresses SATB1-induced malignant progression in breast
            epithelial cells
  JOURNAL   PLoS ONE 7 (12), E51786 (2012)
   PUBMED   23251624
  REMARK    GeneRIF: These data indicate a novel role for ATM as a suppressor
            of SATB1-induced malignancy in breast epithelial cells.
REFERENCE   4  (bases 1 to 5652)
  AUTHORS   Nodin,B., Johannesson,H., Wangefjord,S., O'Connor,D.P.,
            Lindquist,K.E., Uhlen,M., Jirstrom,K. and Eberhard,J.
  TITLE     Molecular correlates and prognostic significance of SATB1
            expression in colorectal cancer
  JOURNAL   Diagn Pathol 7, 115 (2012)
   PUBMED   22935204
  REMARK    GeneRIF: SATB1 expression is a factor of poor prognosis in
            colorectal cancer.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5652)
  AUTHORS   Oda,M., Kanoh,Y., Watanabe,Y. and Masai,H.
  TITLE     Regulation of DNA replication timing on human chromosome by a
            cell-type specific DNA binding protein SATB1
  JOURNAL   PLoS ONE 7 (8), E42375 (2012)
   PUBMED   22879953
  REMARK    GeneRIF: These results reveal a novel role of SATB1 in cell
            type-specific regulation of replication timing along the
            chromosome.
REFERENCE   6  (bases 1 to 5652)
  AUTHORS   Reddy,P.H., Stockburger,E., Gillevet,P. and Tagle,D.A.
  TITLE     Mapping and characterization of novel (CAG)n repeat cDNAs from
            adult human brain derived by the oligo capture method
  JOURNAL   Genomics 46 (2), 174-182 (1997)
   PUBMED   9417904
REFERENCE   7  (bases 1 to 5652)
  AUTHORS   Xu,L., Deng,H.X., Xia,J.H., Yang,Y., Fan,C.H., Hung,W.Y. and
            Siddque,T.
  TITLE     Assignment of SATB1 to human chromosome band 3p23 by in situ
            hybridization
  JOURNAL   Cytogenet. Cell Genet. 77 (3-4), 205-206 (1997)
   PUBMED   9284917
REFERENCE   8  (bases 1 to 5652)
  AUTHORS   Robertson,N.G., Khetarpal,U., Gutierrez-Espeleta,G.A., Bieber,F.R.
            and Morton,C.C.
  TITLE     Isolation of novel and known genes from a human fetal cochlear cDNA
            library using subtractive hybridization and differential screening
  JOURNAL   Genomics 23 (1), 42-50 (1994)
   PUBMED   7829101
REFERENCE   9  (bases 1 to 5652)
  AUTHORS   Nakagomi,K., Kohwi,Y., Dickinson,L.A. and Kohwi-Shigematsu,T.
  TITLE     A novel DNA-binding motif in the nuclear matrix attachment
            DNA-binding protein SATB1
  JOURNAL   Mol. Cell. Biol. 14 (3), 1852-1860 (1994)
   PUBMED   8114718
REFERENCE   10 (bases 1 to 5652)
  AUTHORS   Dickinson,L.A., Joh,T., Kohwi,Y. and Kohwi-Shigematsu,T.
  TITLE     A tissue-specific MAR/SAR DNA-binding protein with unusual binding
            site recognition
  JOURNAL   Cell 70 (4), 631-645 (1992)
   PUBMED   1505028
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK127242.1, AB209761.1,
            AC144521.9, AA001621.1 and DA938384.1.
            
            Summary: This gene encodes a matrix protein which binds nuclear
            matrix and scaffold-associating DNAs through a unique nuclear
            architecture. The protein recruits chromatin-remodeling factors in
            order to regulate chromatin structure and gene expression. Multiple
            transcript variants encoding different isoforms have been found for
            this gene. [provided by RefSeq, Sep 2010].
            
            Transcript Variant: This variant (3) represents the longest
            transcript and encodes the longest isoform (2).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB209761.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-770               AK127242.1         7-776
            771-1386            AB209761.1         44-659
            1387-1595           AC144521.9         111720-111928       c
            1596-3120           AB209761.1         868-2392
            3121-3121           AC144521.9         74409-74409         c
            3122-4545           AB209761.1         2394-3817
            4546-5350           AK127242.1         4455-5259
            5351-5519           AA001621.1         324-492
            5520-5652           DA938384.1         473-605
FEATURES             Location/Qualifiers
     source          1..5652
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p23"
     gene            1..5652
                     /gene="SATB1"
                     /note="SATB homeobox 1"
                     /db_xref="GeneID:6304"
                     /db_xref="HGNC:10541"
                     /db_xref="MIM:602075"
     exon            1..1711
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     variation       658
                     /gene="SATB1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12022"
     STS             1045..1197
                     /gene="SATB1"
                     /standard_name="SHGC-76759"
                     /db_xref="UniSTS:40064"
     variation       1523
                     /gene="SATB1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:4282080"
     variation       1672
                     /gene="SATB1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1140344"
     variation       1676
                     /gene="SATB1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1140345"
     variation       1682
                     /gene="SATB1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1140346"
     exon            1712..1946
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    1727..1729
                     /gene="SATB1"
                     /note="upstream in-frame stop codon"
     CDS             1736..4123
                     /gene="SATB1"
                     /note="isoform 2 is encoded by transcript variant 3;
                     special AT-rich sequence binding protein 1 (binds to
                     nuclear matrix/scaffold-associating DNA); DNA-binding
                     protein SATB1; special AT-rich sequence-binding protein 1"
                     /codon_start=1
                     /product="DNA-binding protein SATB1 isoform 2"
                     /protein_id="NP_001182399.1"
                     /db_xref="GI:306518684"
                     /db_xref="CCDS:CCDS56242.1"
                     /db_xref="GeneID:6304"
                     /db_xref="HGNC:10541"
                     /db_xref="MIM:602075"
                     /translation="

MDHLNEATQGKEHSEMSNNVSDPKGPPAKIARLEQNGSPLGRGRLGSTGAKMQGVPLKHSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSLGYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLEDLPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGRWYKHFKKTKDMMVEMDSLSELSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPSVRTPLPNLHPGLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQSLNQQYLNHPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEILRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPPSRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWLCELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVPAEQIQSPSPTTLGKGESRGVFLPGLPTPAPWLGAAPQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPRTKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKDNSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD

"
     misc_feature    1955..2242
                     /gene="SATB1"
                     /note="N-terminal domain of SATB1 and similar proteins;
                     Region: SATB1_N; cd11585"
                     /db_xref="CDD:211426"
     misc_feature    order(1958..1960,1964..1966,2015..2029,2033..2035,
                     2129..2131,2135..2137,2144..2149,2165..2176,2198..2203,
                     2210..2218,2222..2227)
                     /gene="SATB1"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:211426"
     misc_feature    2822..3079
                     /gene="SATB1"
                     /note="CUT domain; Region: CUT; pfam02376"
                     /db_xref="CDD:202226"
     misc_feature    3188..3448
                     /gene="SATB1"
                     /note="CUT domain; Region: CUT; pfam02376"
                     /db_xref="CDD:202226"
     misc_feature    3767..3943
                     /gene="SATB1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(3767..3778,3782..3784,3836..3838,3854..3856,
                     3893..3895,3899..3904,3911..3916,3920..3928,3932..3937)
                     /gene="SATB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(3770..3772,3779..3781,3902..3904,3911..3916,
                     3923..3925)
                     /gene="SATB1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     exon            1947..2123
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     exon            2124..2250
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     exon            2251..2374
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     exon            2375..2486
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     exon            2487..2941
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     exon            2942..3154
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     variation       3121
                     /gene="SATB1"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2229261"
     exon            3155..3310
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     exon            3311..3514
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     STS             3369..3496
                     /gene="SATB1"
                     /standard_name="SHGC-76756"
                     /db_xref="UniSTS:75453"
     STS             3397..3754
                     /gene="SATB1"
                     /standard_name="G64287"
                     /db_xref="UniSTS:158642"
     exon            3515..3610
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     exon            3611..5652
                     /gene="SATB1"
                     /inference="alignment:Splign:1.39.8"
     STS             3806..4658
                     /gene="SATB1"
                     /standard_name="SATB1_8610"
                     /db_xref="UniSTS:468672"
     STS             4227..4413
                     /gene="SATB1"
                     /standard_name="D3S4171"
                     /db_xref="UniSTS:29541"
     STS             4248..4415
                     /gene="SATB1"
                     /standard_name="SHGC-8047"
                     /db_xref="UniSTS:7660"
     STS             4361..4527
                     /gene="SATB1"
                     /standard_name="STS-M97287"
                     /db_xref="UniSTS:21723"
     STS             4389..4530
                     /gene="SATB1"
                     /standard_name="RH18154"
                     /db_xref="UniSTS:209606"
     STS             5353..5623
                     /gene="SATB1"
                     /standard_name="SHGC-148967"
                     /db_xref="UniSTS:176709"
     variation       5575
                     /gene="SATB1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3935618"
ORIGIN      

tttctcgctcgctcccgttccccggacgcggcggatgagccggccccgctggggaaggctccgggcggcggcgggcggccgggaggaggctgcgtgctcggggctggggctgcgagcggggtgattttgtattaaaatgaggaggaggaagaagaggcacccacagcggcagcggcggcggcggcggcagcagcagcaggagcagcggcggagagggctgcagcccgggcggacgcgcggagccgagcggggcacggcggcggcagcgacagcggccgggatgagtcaactaataatttaatgggggcagagacggcagcgaggggtagagctagcgagggagagagcgagagaagcagccccgtccggggactcgcgctcacactcacgcacacacacaaacacacacacacctctccctgtgccacccagcaacacccggcctcgtcacaacaacaacagccgcggccgccctctatcctgcccgggggcccagccgaaagccagggcgactctagaggacgctgcccgcccccctctttcatttcgggaaactcctgatcagttttgtcggggtttctgggtttcttttcccccaaagtcctagtgccattgtggtgctcgttgtttacctcggactctggacgagtgagagcttggcgactttttggggggagggggcggggagtttgtcgctgcctaggcggtggaggtggctgggggtgccttctgatcttcctcctcctccccctccccccgaacctcttctctcctcacttgctgggaccccagacgctcacagccccgcgtcaatgggcagggagagggtccttgcggctgttgtcagcgagggcagaatcaaaagtggcattttagtgcctttccggggcttttctcgcgaccccctgccccccaccctcgctgtcccccgctagatgccctcgttgggggtgcgaggctgtggggaaaagtttaaggtttgttaatattagtcgcgattgttggcgaggggggtgggggtgattggaagggaggcgaggtggccttcccaatgcgcgttattcggggttattgaagaataatattgcaagtgacagccagaagtagactttctgtcctcacaccgaagaacccgagtgagcaggagggagggagagacgcgaagagaccttttttcctttttggagaccttgtccgcagtgatttttttttttttaagagaatcctcagtcaccacgtcgtttccccagcaccatcacagtgtacagctcataacgggttttgctttgtttttacgatttccccccaacgaatcacttgtcagatcaattttatcttcttcctcctccctgcttcccactctcccctcctccccatcgcaaaccctgttctctgaggttagacattttacaaacccctatatgttggttttcgaattgtgattttttttttaaacccctttctcatggctactcttctagacgtttatttctgcccttcccccgcttaggggggcgggggtaggggaaaggaaaataatacaatttcaggggaagtcgccttcaggtctgctgcttttttatttttttttttttaattaaaaaaaaaaaggacatagaaaacatcagtcttgaacttctcttcaagaacccgggctgcaaaggaaatctcctttgtttttgttatttatgtgctgtcaagttttgaagtggtgatctttagacagtgactgagtatggatcatttgaacgaggcaactcaggggaaagaacattcagaaatgtctaacaatgtgagtgatccgaagggtccaccagccaagattgcccgcctggagcagaacgggagcccgctaggaagaggaaggcttgggagtacaggtgcaaaaatgcagggagtgcctttaaaacactcgggccatctgatgaaaaccaaccttaggaaaggaaccatgctgccagttttctgtgtggtggaacattatgaaaacgccattgaatatgattgcaaggaggagcatgcagaatttgtgctggtgagaaaggatatgcttttcaaccagctgatcgaaatggcattgctgtctctaggttattcacatagctctgctgcccaggccaaagggctaatccaggttggaaagtggaatccagttccactgtcttacgtgacagatgcccctgatgctacagtagcagatatgcttcaagatgtgtatcatgtggtcacattgaaaattcagttacacagttgccccaaactagaagacttgcctcccgaacaatggtcgcacaccacagtgaggaatgctctgaaggacttactgaaagatatgaatcagagttcattggccaaggagtgccccctttcacagagtatgatttcttccattgtgaacagtacttactatgcaaatgtctcagcagcaaaatgtcaagaatttggaaggtggtacaaacatttcaagaagacaaaagatatgatggttgaaatggatagtctttctgagctatcccagcaaggcgccaatcatgtcaattttggccagcaaccagttccagggaacacagccgagcagcctccatcccctgcgcagctctcccatggcagccagccctctgtccggacacctcttccaaacctgcaccctgggctcgtatcaacacctatcagtcctcaattggtcaaccagcagctggtgatggctcagctgctgaaccagcagtatgcagtgaatagacttttagcccagcagtccttaaaccaacaatacttgaaccaccctccccctgtcagtagatctatgaataagcctttggagcaacaggtttcgaccaacacagaggtgtcttccgaaatctaccagtgggtacgcgatgaactgaaacgagcaggaatctcccaggcggtatttgcacgtgtggcttttaacagaactcagggcttgctttcagaaatcctccgaaaggaagaggaccccaagactgcatcccagtctttgctggtaaaccttcgggctatgcagaatttcttgcagttaccggaagctgaaagagaccgaatataccaggacgaaagggaaaggagcttgaatgctgcctcggccatgggtcctgcccccctcatcagcacaccacccagccgtcctccccaggtgaaaacagctactattgccactgaaaggaatgggaaaccagagaacaataccatgaacattaatgcttccatttatgatgagattcagcaggaaatgaagcgtgctaaagtgtctcaagcactgtttgcaaaggttgcagcaaccaaaagccagggatggttgtgcgagctgttacgctggaaagaagatccttctccagaaaacagaaccctgtgggagaacctctccatgatccgaaggttcctcagtcttcctcagccagaacgtgatgccatttatgaacaggagagcaacgcggtgcatcaccatggcgacaggccgccccacattatccatgttccagcagagcagattcagagcccctctcccaccacccttgggaaaggagagtctagaggcgttttcttaccaggcctgccgacccctgcaccatggctcggtgctgctcctcagcaacagcagcagcaacagcaacagcagcagcagcagcagcaggcaccgccgcctccacagccacagcagcagccacagacaggccctcggctccccccacggcaacccacggtggcctctccagcagagtcagatgaggaaaaccgacagaagacccggccacgaacaaaaatttcagtggaagccttgggaatcctccagagtttcatacaagacgtgggcctgtaccctgacgaagaggccatccagactctgtctgcccagctcgaccttcccaagtacaccatcatcaagttctttcagaaccagcggtactatctcaagcaccacggcaaactgaaggacaattccggtttagaggtcgatgtggcagaatataaagaagaggagctgctgaaggatttggaagagagtgtccaagataaaaatactaacacccttttttcagtgaaactagaagaagagctgtcagtggaaggaaacacagacattaatactgatttgaaagactgagataaaagtatttgtttcgttcaacagtgccactggtatttactaacaaaatgaaaagtccaccttgtcttctctcagaaaacctttgttgttcattgtttggccaatgaatcttcaaaaacttgcacaaacagaaaagttggaaaaggataatacagactgcactaaatgttttcctctgttttacaaactgcttggcagccccaggtgaagcatcaaggattgtttggtattaaaatttgtgttcacgggatgcaccaaagtgtgtaccccgtaagcatgaaaccagtgttttttgttttttttttagttcttattccggagcctcaaacaagcattataccttctgtgattatgatttcctctcctataattatttctgtagcactccacactgatctttggaaacttgccccttatttaaaaaaaaaaaagaaaaaaaagagtttgttactctattgtatgttacaaaagaactatagactgtggaatgcagtttaaagatgacatatgccaacaaatgccttgtattatatggcactgccgtaattcaaatttgtttttattttggaaataaaagttcactgtacttttttttcattctcattgttacatgattttttaaaaaaaggaaaagaaaatgtgaaacacaatttagtcctcattatttatttgtagatcctgcagcatcatgttgtaattaattttttggaagtttccgttaaatgtaatattgcttctcttgttaccatactgattcttttctatttataaatgtattttgatgggcagtaaaacaaagtgtcttaaaagttttaaatagagaaaatgtgctttacacagttgcctataaaaagtgctctatgttatccaagcaattcatactataagcttcactcttattgttgtatgcaatttttactatcatgcaaataagcttaggtaaataaaactaatagatcaccttagaaaattatgcaattaatgtgaaaataattgatgtttgcaatgtgtcttcctttggtttacaatcaattttaaagctacatctgtataaaatttctgtataaaggtgtatttcttttttatgagtttatggctatgaaaacagctattttgttacagctggctgtttttataagtgtatcacaattttctttatgcagaaatgttctgactaggagtggttattgactgtaactacacaattaaaattgtttgtatcgtatgacatggtagggtttgtctgcttatgtgaagtaactaaaggagtcaaaggatggccctctcatttaggtgcatgttaataacttgttatttcactgattttaaaaagagcaattgacaagttacttgaaacactgtaaatttaaatcacaaacacatgctcatttttaaataggtatgaaatttcacaatgaaaataacctgtttggttaacattttgcttaataagtagagataggatggtcaaaagactctccgacaaaaacaaatccagtctctagcagttatgttgttagaatgga

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:6304 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA
            GeneID:6304 -> Molecular function: GO:0003690 [double-stranded DNA binding] evidence: TAS
            GeneID:6304 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:6304 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:6304 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:6304 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IMP
            GeneID:6304 -> Biological process: GO:0006325 [chromatin organization] evidence: TAS
            GeneID:6304 -> Biological process: GO:0006338 [chromatin remodeling] evidence: IEA
            GeneID:6304 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:6304 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
            GeneID:6304 -> Biological process: GO:0006921 [cellular component disassembly involved in execution phase of apoptosis] evidence: TAS
            GeneID:6304 -> Biological process: GO:0008544 [epidermis development] evidence: IEA
            GeneID:6304 -> Biological process: GO:0016571 [histone methylation] evidence: IEA
            GeneID:6304 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
            GeneID:6304 -> Biological process: GO:0043367 [CD4-positive, alpha-beta T cell differentiation] evidence: IEA
            GeneID:6304 -> Biological process: GO:0043374 [CD8-positive, alpha-beta T cell differentiation] evidence: IEA
            GeneID:6304 -> Biological process: GO:0050798 [activated T cell proliferation] evidence: IEA
            GeneID:6304 -> Biological process: GO:0060004 [reflex] evidence: IEA
            GeneID:6304 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:6304 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
            GeneID:6304 -> Cellular component: GO:0005720 [nuclear heterochromatin] evidence: IEA
            GeneID:6304 -> Cellular component: GO:0016363 [nuclear matrix] evidence: IEA
            GeneID:6304 -> Cellular component: GO:0016605 [PML body] evidence: IDA