LOCUS       NM_001189               2241 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens NK3 homeobox 2 (NKX3-2), mRNA.
ACCESSION   NM_001189
VERSION     NM_001189.3  GI:155030212
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2241)
  AUTHORS   Choi,S.W., Jeong,D.U., Kim,J.A., Lee,B., Joeng,K.S., Long,F. and
            Kim,D.W.
  TITLE     Indian Hedgehog signalling triggers Nkx3.2 protein degradation
            during chondrocyte maturation
  JOURNAL   Biochem. J. 443 (3), 789-798 (2012)
   PUBMED   22507129
  REMARK    GeneRIF: Ihh-induced Nkx3.2 degradation requires Wnt5a, which is
            capable of triggering Nkx3.2 degradation
REFERENCE   2  (bases 1 to 2241)
  AUTHORS   Yong,Y., Choi,S.W., Choi,H.J., Nam,H.W., Kim,J.A., Jeong,D.U.,
            Kim,D.Y., Kim,Y.S. and Kim,D.W.
  TITLE     Exogenous signal-independent nuclear IkappaB kinase activation
            triggered by Nkx3.2 enables constitutive nuclear degradation of
            IkappaB-alpha in chondrocytes
  JOURNAL   Mol. Cell. Biol. 31 (14), 2802-2816 (2011)
   PUBMED   21606193
  REMARK    GeneRIF: Data show that IkappaB kinase beta (IKKbeta) can be
            activated in the nucleus by Nkx3.2 in the absence of exogenous
            IKK-activating signals, allowing constitutive nuclear degradation
            of IkappaB-alpha.
REFERENCE   3  (bases 1 to 2241)
  AUTHORS   Hellemans,J., Simon,M., Dheedene,A., Alanay,Y., Mihci,E., Rifai,L.,
            Sefiani,A., van Bever,Y., Meradji,M., Superti-Furga,A. and
            Mortier,G.
  TITLE     Homozygous inactivating mutations in the NKX3-2 gene result in
            spondylo-megaepiphyseal-metaphyseal dysplasia
  JOURNAL   Am. J. Hum. Genet. 85 (6), 916-922 (2009)
   PUBMED   20004766
  REMARK    GeneRIF: NKX3-2 plays an important role in endochondral
            ossification of both the axial and appendicular skeleton in humans
REFERENCE   4  (bases 1 to 2241)
  AUTHORS   Rodrigo,I., Bovolenta,P., Mankoo,B.S. and Imai,K.
  TITLE     Meox homeodomain proteins are required for Bapx1 expression in the
            sclerotome and activate its transcription by direct binding to its
            promoter
  JOURNAL   Mol. Cell. Biol. 24 (7), 2757-2766 (2004)
   PUBMED   15024065
  REMARK    GeneRIF: Data show that Meox1 activates the Bapx1 promoter in a
            dose-dependent manner and that this activity is enhanced in the
            presence of Pax1 and/or Pax9.
REFERENCE   5  (bases 1 to 2241)
  AUTHORS   Tribioli,C. and Lufkin,T.
  TITLE     Molecular cloning, chromosomal mapping and developmental expression
            of BAPX1, a novel human homeobox-containing gene homologous to
            Drosophila bagpipe
  JOURNAL   Gene 203 (2), 225-233 (1997)
   PUBMED   9426254
REFERENCE   6  (bases 1 to 2241)
  AUTHORS   Yoshiura,K.I. and Murray,J.C.
  TITLE     Sequence and chromosomal assignment of human BAPX1, a
            bagpipe-related gene, to 4p16.1: a candidate gene for skeletal
            dysplasia
  JOURNAL   Genomics 45 (2), 425-428 (1997)
   PUBMED   9344671
REFERENCE   7  (bases 1 to 2241)
  AUTHORS   Tribioli,C., Frasch,M. and Lufkin,T.
  TITLE     Bapx1: an evolutionary conserved homologue of the Drosophila
            bagpipe homeobox gene is expressed in splanchnic mesoderm and the
            embryonic skeleton
  JOURNAL   Mech. Dev. 65 (1-2), 145-162 (1997)
   PUBMED   9256352
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC111966.1 and AC006445.11.
            This sequence is a reference standard in the RefSeqGene project.
            On Aug 10, 2007 this sequence version replaced gi:25121985.
            
            Summary: This gene encodes a member of the NK family of
            homeobox-containing proteins. The encoded protein may play a role
            in skeletal development. [provided by RefSeq, Jul 2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF009801.1, BC111966.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025087, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1111              BC111966.1         1-1111
            1112-2241           AC006445.11        110916-112045
FEATURES             Location/Qualifiers
     source          1..2241
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p16.3"
     gene            1..2241
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /note="NK3 homeobox 2"
                     /db_xref="GeneID:579"
                     /db_xref="HGNC:951"
                     /db_xref="HPRD:09075"
                     /db_xref="MIM:602183"
     STS             1..1111
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /db_xref="UniSTS:490189"
     exon            1..542
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(46)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369274169"
     variation       complement(67)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:138460070"
     STS             77..1128
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /db_xref="UniSTS:481599"
     CDS             77..1078
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /note="homeobox protein NK-3 homolog B; bagpipe homeobox
                     protein homolog 1"
                     /codon_start=1
                     /product="homeobox protein Nkx-3.2"
                     /protein_id="NP_001180.1"
                     /db_xref="GI:4502365"
                     /db_xref="CCDS:CCDS3410.1"
                     /db_xref="GeneID:579"
                     /db_xref="HGNC:951"
                     /db_xref="HPRD:09075"
                     /db_xref="MIM:602183"
                     /translation="

MAVRGANTLTSFSIQAILNKKEERGGLAAPEGRPAPGGTAASVAAAPAVCCWRLFGERDAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAGGSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYYYPYYCLPGWALSTCAAAAGTQ

"
     misc_feature    713..871
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(713..715,764..766,782..784,821..823,827..832,
                     839..844,848..856,860..865)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(830..832,839..844,851..853)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     variation       complement(105)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369239936"
     variation       complement(109)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117393870"
     variation       complement(158)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34942446"
     variation       complement(184)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200291862"
     variation       complement(211)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371388996"
     variation       complement(212)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368562579"
     variation       complement(224)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371597026"
     variation       complement(266)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202195290"
     variation       complement(280)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201112176"
     variation       complement(300)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374854852"
     variation       complement(311)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200167000"
     variation       complement(323)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:9684692"
     variation       complement(349)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201772546"
     variation       complement(367)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:112448315"
     variation       complement(399)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202191746"
     variation       complement(427)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145908097"
     variation       complement(452)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368263938"
     variation       complement(505)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10032202"
     variation       complement(515)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370578004"
     exon            543..2241
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(569)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61795263"
     variation       complement(615)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199921924"
     variation       complement(675)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377066284"
     variation       complement(710)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372506158"
     variation       complement(733)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371570785"
     variation       complement(744)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376860038"
     variation       complement(918)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373154511"
     variation       complement(987)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201832139"
     variation       complement(994)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200958836"
     variation       complement(995)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141572096"
     variation       complement(1018)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:111283169"
     variation       complement(1063)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144770764"
     variation       complement(1160)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374816985"
     variation       complement(1173)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:191302851"
     variation       complement(1254)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114089334"
     variation       complement(1358)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186403807"
     variation       complement(1364)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:180830199"
     variation       complement(1435)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:189823186"
     variation       complement(1448)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186240926"
     variation       complement(1518)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113707415"
     variation       complement(1533)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182009909"
     variation       complement(1570)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:77330525"
     variation       complement(1571)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145749128"
     variation       complement(1604)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367990237"
     variation       complement(1625)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141974005"
     variation       complement(1685)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:189366144"
     variation       complement(1808)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4698712"
     variation       complement(1811)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3733554"
     variation       complement(1825)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:79270590"
     variation       complement(1862)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61795262"
     variation       complement(1947)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370696974"
     variation       complement(2021)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3822226"
     variation       complement(2024)
                     /gene="NKX3-2"
                     /gene_synonym="BAPX1; NKX3.2; NKX3B; SMMD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111445770"
ORIGIN      

ggcgctctctgtcccgctcggagctgctcggcgccccagctgcccgccccgccggccgctcctgcccgcggcgcagatggctgtgcgcggcgccaacaccttgacgtccttctccatccaggcgatcctcaacaagaaagaggagcgcggcgggctggccgcgccagaggggcgcccggcgcccgggggcacagcggcatcggtggccgcggctcccgctgtctgctgttggcggctctttggggagagggacgcgggcgcgttggggggcgccgaggactctctgctggcgtctcctgccggtaccagaacagctgcggggcggactgcggagagcccggaaggctgggactcggactccgcgctcagcgaggagaacgagagcaggcggcgctgcgcggacgcgcggggggccagcggggccggccttgcggggggatccttgagcctcggccagccggtctgtgagctggccgcttccaaagacctagaggaggaagccgcgggccggagcgacagcgagatgtccgccagcgtctcaggcgaccgcagcccaaggaccgaggacgacggtgttggccccagaggtgcacacgtgtccgcgctgtgcagcggggccggcggcgggggcggcagcgggccggcaggcgtcgcggaggaggaggaggagccggcggcgcccaagccacgcaagaagcgctcgcgggccgctttctcccacgcgcaggtcttcgagctggagcgccgctttaaccaccagcgctacctgtccgggcccgagcgcgcagacctggccgcgtcgctgaagctcaccgagacgcaggtgaaaatctggttccagaaccgtcgctacaagacaaagcgccggcagatggcagccgacctgctggcctcggcgcccgccgccaagaaggtggccgtaaaggtgctggtgcgcgacgaccagagacaatacctgcccggcgaagtgctgcggccaccctcgcttctgccactgcagccctcctactattacccgtactactgcctcccaggctgggcgctctccacctgcgcagctgccgcaggcacccagtgaacccgcttgggctgaggcagcgagtgattcccgcgctccggctccggaccggcgctgacagctgtaggctgtagcctgcacggggcgccccgccaaggaggcacctggaggtgaaacccagctccagctcccgttagccaggacttgtcccctggcagctgggctgagtctgccctgagggggcgcctttttctaatttgaacagaggcaccctatggcctaggggccctgatcgcccacctgcctggaagcccctgggctctatttattatcatgacaatgttggaattaaattttgattcgaatatgtctgcctgggggtggggttttccctgagcggcaactcctggagaccacatagcctgaatcctcagaatttcaggcctgctgggagctttctgcactaggccacactagttcatggtatccatgctaccaatctatgtgtatctacatatcttttatttttggaaattgcatttgtaaccaaggggtgcgaaaccctggcagtcccaggcagcaccaggccaggggttgatttgaaacgtgaaggattgggttttcaggccctctgctccacccctcctgtgtgtcagagctagggtgggggtgcccgattcgggtgctgaatgtaaggaggggagcctccaagtgtggtgcaagccgggggtctccacatcttccttctctgaagtccaggtacctgcacaagcaggaagcgcctgggagtcccggaaggaggagagcgcacacccaggcagccctctgcggaaactttccttggtttctttttatttgtgtaaaggaggttaagacgtgtcgcacttttcagttgtttgtattcaaatgacgattatttttctactcaatgtgaatatccctggccagcctttccacggcgcccaccgcagtgccgctgcctggccctcagtgtctaccttctgccctctgcgactccagtgctctggcccgggactcccctatccgcccctcacttacccttaaacaggtgatcccacctgtcttgtcaacctcgccgcttttcgcctccttaatggcactgtgcactcaactagagtattaactgtaaaaagatttgtgaagtttggaagctctattcgctgtattttttctttaatttataaacttttagtttaacatgc

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:579 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:579 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:579 -> Biological process: GO:0001501 [skeletal system development] evidence: TAS
            GeneID:579 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
            GeneID:579 -> Biological process: GO:0007368 [determination of left/right symmetry] evidence: IEA
            GeneID:579 -> Biological process: GO:0031016 [pancreas development] evidence: IEA
            GeneID:579 -> Biological process: GO:0032331 [negative regulation of chondrocyte differentiation] evidence: ISS
            GeneID:579 -> Biological process: GO:0042474 [middle ear morphogenesis] evidence: IEA
            GeneID:579 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: IEA
            GeneID:579 -> Biological process: GO:0048536 [spleen development] evidence: IEA
            GeneID:579 -> Biological process: GO:0048645 [organ formation] evidence: IEA
            GeneID:579 -> Biological process: GO:0048705 [skeletal system morphogenesis] evidence: IEA
            GeneID:579 -> Biological process: GO:0048706 [embryonic skeletal system development] evidence: IEA
            GeneID:579 -> Biological process: GO:0060576 [intestinal epithelial cell development] evidence: IEA
            GeneID:579 -> Cellular component: GO:0005634 [nucleus] evidence: IEA