LOCUS       NM_001174096            6001 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens zinc finger E-box binding homeobox 1 (ZEB1),
            transcript variant 9, mRNA.
ACCESSION   NM_001174096
VERSION     NM_001174096.1  GI:291575191
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6001)
  AUTHORS   Lemma,S., Karihtala,P., Haapasaari,K.M., Jantunen,E., Soini,Y.,
            Bloigu,R., Pasanen,A.K., Turpeenniemi-Hujanen,T. and Kuittinen,O.
  TITLE     Biological roles and prognostic values of the
            epithelial-mesenchymal transition-mediating transcription factors
            Twist, ZEB1 and Slug in diffuse large B-cell lymphoma
  JOURNAL   Histopathology 62 (2), 326-333 (2013)
   PUBMED   23190132
  REMARK    GeneRIF: In diffuse large B-cell lymphoma, cytoplasmic Slug
            expression was linked to a favourable disease outcome, whereas
            nuclear expression of ZEB1 indicated an adverse outcome.
REFERENCE   2  (bases 1 to 6001)
  AUTHORS   Lechner,J., Dash,D.P., Muszynska,D., Hosseini,M., Segev,F.,
            George,S., Frazer,D.G., Moore,J.E., Kaye,S.B., Young,T.,
            Simpson,D.A., Churchill,A.J., Heon,E. and Willoughby,C.E.
  TITLE     Mutational spectrum of the ZEB1 gene in corneal dystrophies
            supports a genotype-phenotype correlation
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 54 (5), 3215-3223 (2013)
   PUBMED   23599324
  REMARK    GeneRIF: Missense substitutions in the ZEB1 protein are associated
            with FECD6 and keratoconus, whereas protein truncating ZEB1
            mutations result in PPCD3.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6001)
  AUTHORS   Guo,S., Li,Y., Tong,Q., Gu,F., Zhu,T., Fu,L. and Yang,S.
  TITLE     deltaEF1 down-regulates ER-alpha expression and confers tamoxifen
            resistance in breast cancer
  JOURNAL   PLoS ONE 7 (12), E52380 (2012)
   PUBMED   23285017
  REMARK    GeneRIF: The expression of deltaEF1 is up-regulated by
            17beta-estradiol (E2) in MCF-7 cells in an ER-alpha-dependent
            manner.
REFERENCE   4  (bases 1 to 6001)
  AUTHORS   Mehta,J.S., Vithana,E.N., Tan,D.T., Yong,V.H., Yam,G.H., Law,R.W.,
            Chong,W.G., Pang,C.P. and Aung,T.
  TITLE     Analysis of the posterior polymorphous corneal dystrophy 3 gene,
            TCF8, in late-onset Fuchs endothelial corneal dystrophy
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 49 (1), 184-188 (2008)
   PUBMED   18172091
  REMARK    GeneRIF: The identification of a novel missense mutation in only
            one of the patients implied that TCF8 does not play a significant
            role in the pathogenesis of FECD in this Chinese population.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   5  (bases 1 to 6001)
  AUTHORS   Manavella,P.A., Roqueiro,G., Darling,D.S. and Cabanillas,A.M.
  TITLE     The ZFHX1A gene is differentially autoregulated by its isoforms
  JOURNAL   Biochem. Biophys. Res. Commun. 360 (3), 621-626 (2007)
   PUBMED   17610840
  REMARK    GeneRIF: The Zfhx1a-1 gene is autoregulated in part by negative
            feedback on its own promoter which is, in turn, modified by the
            availability of the negative dominant isoform Zfhx1a-2.
REFERENCE   6  (bases 1 to 6001)
  AUTHORS   Liskova,P., Tuft,S.J., Gwilliam,R., Ebenezer,N.D., Jirsova,K.,
            Prescott,Q., Martincova,R., Pretorius,M., Sinclair,N., Boase,D.L.,
            Jeffrey,M.J., Deloukas,P., Hardcastle,A.J., Filipec,M. and
            Bhattacharya,S.S.
  TITLE     Novel mutations in the ZEB1 gene identified in Czech and British
            patients with posterior polymorphous corneal dystrophy
  JOURNAL   Hum. Mutat. 28 (6), 638 (2007)
   PUBMED   17437275
  REMARK    GeneRIF: Four novel pathogenic mutations were identified in four
            families; two deletions, one nonsense, and one duplication within
            exon 7 in the ZEB1 gene at 10p11.2. Czech patients were genotyped
            for a founder haplotype and lack of 20p11.2 locus segregation.
REFERENCE   7  (bases 1 to 6001)
  AUTHORS   Franklin,A.J., Jetton,T.L., Shelton,K.D. and Magnuson,M.A.
  TITLE     BZP, a novel serum-responsive zinc finger protein that inhibits
            gene transcription
  JOURNAL   Mol. Cell. Biol. 14 (10), 6773-6788 (1994)
   PUBMED   7935395
REFERENCE   8  (bases 1 to 6001)
  AUTHORS   Watanabe,Y., Kawakami,K., Hirayama,Y. and Nagano,K.
  TITLE     Transcription factors positively and negatively regulating the
            Na,K-ATPase alpha 1 subunit gene
  JOURNAL   J. Biochem. 114 (6), 849-855 (1993)
   PUBMED   8138542
REFERENCE   9  (bases 1 to 6001)
  AUTHORS   Williams,T.M., Montoya,G., Wu,Y., Eddy,R.L., Byers,M.G. and
            Shows,T.B.
  TITLE     The TCF8 gene encoding a zinc finger protein (Nil-2-a) resides on
            human chromosome 10p11.2
  JOURNAL   Genomics 14 (1), 194-196 (1992)
   PUBMED   1427828
REFERENCE   10 (bases 1 to 6001)
  AUTHORS   Williams,T.M., Moolten,D., Burlein,J., Romano,J., Bhaerman,R.,
            Godillot,A., Mellon,M., Rauscher,F.J. III and Kant,J.A.
  TITLE     Identification of a zinc finger protein that inhibits IL-2 gene
            expression
  JOURNAL   Science 254 (5039), 1791-1794 (1991)
   PUBMED   1840704
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DB442432.1, DC299346.1,
            BC112392.1, AL831979.1, AI086650.1, BX111519.1 and BQ003893.1.
            
            Summary: This gene encodes a zinc finger transcription factor. The
            encoded protein likely plays a role in transcriptional repression
            of interleukin 2. Mutations in this gene have been associated with
            posterior polymorphous corneal dystrophy-3 and late-onset Fuchs
            endothelial corneal dystrophy. Alternatively spliced transcript
            variants encoding different isoforms have been described.[provided
            by RefSeq, Mar 2010].
            
            Transcript Variant: This variant (9) differs in the 5' UTR, lacks a
            portion of the 5' coding region, and initiates translation at an
            alternate start codon, compared to variant 1. The encoded isoform
            (f) is longer and has a distinct N-terminus, compared to isoform a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC112392.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                DB442432.1         1-24
            25-47               DC299346.1         1-23
            48-3630             BC112392.1         1-3583
            3631-5116           AL831979.1         3886-5371
            5117-5282           AI086650.1         103-268             c
            5283-5416           BX111519.1         1-134
            5417-6001           BQ003893.1         8-592               c
FEATURES             Location/Qualifiers
     source          1..6001
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10p11.2"
     gene            1..6001
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="zinc finger E-box binding homeobox 1"
                     /db_xref="GeneID:6935"
                     /db_xref="HGNC:11642"
                     /db_xref="MIM:189909"
     exon            1..121
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    31..33
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="upstream in-frame stop codon"
     variation       36
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367615307"
     CDS             64..3441
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="isoform f is encoded by transcript variant 9; zinc
                     finger homeodomain enhancer-binding protein; posterior
                     polymorphous corneal dystrophy 3; transcription factor 8
                     (represses interleukin 2 expression); delta-crystallin
                     enhancer binding factor 1; negative regulator of IL2"
                     /codon_start=1
                     /product="zinc finger E-box-binding homeobox 1 isoform f"
                     /protein_id="NP_001167567.1"
                     /db_xref="GI:291575192"
                     /db_xref="CCDS:CCDS53505.1"
                     /db_xref="GeneID:6935"
                     /db_xref="HGNC:11642"
                     /db_xref="MIM:189909"
                     /translation="

MADGPRCKRRKQANPRRNNVTNYNTVVETNSDSDDEDKLHIVEEESVTDAADCEGVPEDDLPTDQTVLPGRSSEREGNAKNCWEDDTGKEGQEILGPEAQADEAGCTVKDDECESDAENEQNHDPNVEEFLQQQDTAVIFPEAPEEDQRQGTPEASGHDENGTPDAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLERHMTSHKSGRDQRHVTQSGCNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLIPVNGRPRTGLKTSQCSSPSLSASPGSPTRPQIRQKIENKPLQEQLSVNQIKTEPVDYEFKPIVVASGINCSTPLQNGVFTGGGPLQATSSPQGMVQAVVLPTVGLVSPISINLSDIQNVLKVAVDGNVIRQVLENNQANLASKEQETINASPIQQGGHSVISAISLPLVDQDGTTKIIINYSLEQPSQLQVVPQNLKKENPVATNSCKSEKLPEDLTVKSEKDKSFEGGVNDSTCLLCDDCPGDINALPELKHYDLKQPTQPPPLPAAEAEKPESSVSSATGDGNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAGQISVQSSEPSSPEPGKVNIPAKNNDQPQSANANEPQDSTVNLQSPLKMTNSPVLPVGSTTNGSRSSTPSPSPLNLSSSRNTQGYLYTAEGAQEEPQVEPLDLSLPKQQGELLERSTITSVYQNSVYSVQEEPLNLSCAKKEPQKDSCVTDSEPVVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYSTTVSPAVQEPPLKVIQPNGNQDERQDTSSEGVSNVEDQNDSDSTPPKKKMRKTENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEKTNEA

"
     misc_feature    664..732
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="Zinc finger, C2H2 type; Region: zf-C2H2; cl15478"
                     /db_xref="CDD:210117"
     misc_feature    784..852
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="zinc finger; Region: ZnF_C2H2; smart00355"
                     /db_xref="CDD:197676"
     misc_feature    826..897
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="Zinc-finger double domain; Region: zf-H2C2_2;
                     pfam13465"
                     /db_xref="CDD:205643"
     misc_feature    1030..1032
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P37275.2); phosphorylation site"
     misc_feature    1843..1968
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(1879..1881,1897..1899,1936..1938,1942..1947,
                     1954..1959,1963..1968)
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(1945..1947,1954..1959,1966..1968)
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     misc_feature    1990..1992
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P37275.2); phosphorylation site"
     misc_feature    2101..2103
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P37275.2); phosphorylation site"
     misc_feature    2170..2172
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (P37275.2); phosphorylation site"
     misc_feature    2818..2895
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="Zinc-finger double domain; Region: zf-H2C2_2;
                     pfam13465"
                     /db_xref="CDD:205643"
     misc_feature    2902..2979
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /note="Zinc-finger double domain; Region: zf-H2C2_2;
                     pfam13465"
                     /db_xref="CDD:205643"
     exon            122..322
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       148
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375120441"
     variation       163..165
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="gat"
                     /db_xref="dbSNP:141941188"
     variation       176
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184444132"
     variation       181
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369331715"
     variation       228
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148639111"
     variation       243
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142039874"
     variation       255
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7918614"
     variation       296
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:80194531"
     variation       305
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189276857"
     exon            323..385
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       334
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12217419"
     variation       357
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:11559173"
     variation       380
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367732931"
     exon            386..547
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       403
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369476602"
     variation       459
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189111678"
     variation       517
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202218576"
     variation       530
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369587040"
     exon            548..750
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       555
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142133469"
     variation       657
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150051354"
     variation       669
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79134358"
     variation       676
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201419824"
     exon            751..856
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       761
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370082712"
     variation       762
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149166539"
     variation       855
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143232269"
     exon            857..2667
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       942
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374468151"
     variation       947
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370663355"
     variation       1008
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373826858"
     variation       1024
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371970352"
     variation       1032
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199664973"
     variation       1117
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367672138"
     variation       1124
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:148310638"
     variation       1147
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:192544989"
     variation       1188
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113838847"
     variation       1213
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142232415"
     variation       1269
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145398072"
     variation       1270
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371431986"
     variation       1279
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146384341"
     variation       1307
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138491446"
     variation       1315
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145576217"
     variation       1323
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35238902"
     variation       1325
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:75910137"
     variation       1330
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201283071"
     variation       1379
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148867206"
     variation       1393
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:150669496"
     variation       1487
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199595565"
     variation       1504
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374398055"
     variation       1561
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139511659"
     variation       1592
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149705490"
     variation       1593
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144430294"
     variation       1635
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:35708848"
     variation       1672
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368461324"
     variation       1724
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35753967"
     variation       1751
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140611114"
     variation       1767
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372068000"
     variation       1770
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:184880161"
     variation       1810
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143542961"
     variation       1818
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:367749817"
     variation       1839
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371536001"
     variation       1841
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375798509"
     variation       1860
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369994958"
     variation       1910
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373879318"
     variation       1941
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142143222"
     variation       1965
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201912416"
     variation       1969
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151017318"
     variation       2012
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370211218"
     variation       2040
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:151205909"
     variation       2043
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140987489"
     variation       2045
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150228807"
     variation       2057
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:141110915"
     variation       2100
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146821579"
     variation       2127
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:34846414"
     variation       2136
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35501784"
     variation       2145
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:75229306"
     variation       2220
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34111864"
     variation       2250
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200572671"
     variation       2261
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372597335"
     variation       2269
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138456617"
     variation       2305
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:117534296"
     variation       2317
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138507868"
     variation       2347
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200667415"
     variation       2357
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376963555"
     variation       2382
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143340752"
     variation       2384
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201927623"
     variation       2463..2464
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35905383"
     variation       2473
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148358382"
     variation       2477
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1577181"
     variation       2482
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141194628"
     variation       2495
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199944415"
     variation       2508
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200125768"
     variation       2550
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201567879"
     variation       2585
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:118020901"
     variation       2622
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367685869"
     variation       2626
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139581793"
     variation       2654
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202145455"
     exon            2668..2848
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       2683
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369581136"
     variation       2734
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143370284"
     variation       2738
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369330183"
     variation       2756
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35653460"
     variation       2769
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147142042"
     variation       2773
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184220160"
     variation       2780
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:78449005"
     exon            2849..5991
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /inference="alignment:Splign:1.39.8"
     variation       2860
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370801976"
     variation       2918
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374536300"
     variation       2953
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149757409"
     variation       2964
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145553237"
     variation       3036
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376922710"
     variation       3049
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371696203"
     variation       3097
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148446855"
     variation       3111
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200948247"
     variation       3119
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200238558"
     variation       3127
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142629102"
     variation       3132
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146803682"
     variation       3156
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140617391"
     variation       3158
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:145633572"
     variation       3237
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146561222"
     variation       3256..3258
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="gaa"
                     /db_xref="dbSNP:375988551"
     variation       3258..3260
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="aga"
                     /db_xref="dbSNP:370699695"
     variation       3259..3261
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="gag"
                     /db_xref="dbSNP:369270839"
     variation       3293
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:375270538"
     variation       3295
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146672684"
     variation       3307
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140217290"
     variation       3323
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201845244"
     variation       3353
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:141086946"
     variation       3366
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34256798"
     variation       3374
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150279725"
     variation       3379
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138952579"
     variation       3397
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143438972"
     variation       3454
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188563673"
     variation       3487
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113977142"
     variation       3491
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374867798"
     STS             3499..3649
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /standard_name="D10S1781"
                     /db_xref="UniSTS:34015"
     variation       3510
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78595841"
     STS             3519..3735
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /standard_name="SHGC-31480"
                     /db_xref="UniSTS:26889"
     variation       3589..3590
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="ac"
                     /db_xref="dbSNP:143911186"
     variation       3590..3591
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="ac"
                     /db_xref="dbSNP:72221464"
     variation       3615..3620
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="cacaca"
                     /db_xref="dbSNP:36207630"
     variation       3617..3622
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="cacaca"
                     /db_xref="dbSNP:5784248"
     variation       3618..3621
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="acac"
                     /db_xref="dbSNP:10610992"
     variation       3620..3625
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="acacac"
                     /db_xref="dbSNP:3086583"
     variation       3627..3630
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="caca"
                     /db_xref="dbSNP:60354357"
     variation       3630..3631
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:71027030"
     variation       3707
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372557668"
     variation       3784
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148015830"
     variation       3795
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372771766"
     variation       3827
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141676377"
     variation       3845
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10490929"
     variation       4124..4127
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="actc"
                     /db_xref="dbSNP:376070628"
     variation       4283
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150246922"
     variation       4335..4342
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="gtattttc"
                     /db_xref="dbSNP:368007808"
     variation       4397
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:193087933"
     variation       4422
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139194135"
     variation       4750
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:185686910"
     variation       4815..4816
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:149726475"
     variation       4998
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:118189529"
     variation       5072
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2839667"
     variation       5078
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191505587"
     variation       5154
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7349"
     variation       5222
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:183651581"
     variation       5226
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:188702835"
     variation       5407
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:77992406"
     variation       5459
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75678706"
     variation       5501..5502
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:201215623"
     variation       5580
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143336093"
     variation       5610
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75717753"
     variation       5654
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147527127"
     variation       5656
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200534090"
     variation       5774
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181434712"
     variation       5812
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:220071"
     variation       5856
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184147533"
     variation       5861
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190131604"
     polyA_signal    5960..5965
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
     polyA_site      5991
                     /gene="ZEB1"
                     /gene_synonym="AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3;
                     TCF8; ZFHEP; ZFHX1A"
ORIGIN      

gggggggaagggggagggagggggaggaggtgactcgagcatttagacacaagcgagaggatcatggcggatggccccaggtgtaagcgcagaaagcaggcgaacccgcggcgcaataacgttacaaattataatactgtggtagaaacaaattcagattcagatgatgaagacaaactgcatattgtggaagaagaaagtgttacagatgcagctgactgtgaaggtgtaccagaggatgacctgccaacagaccagacagtgttaccagggaggagcagtgaaagagaagggaatgctaagaactgctgggaggatgacacaggaaaggaagggcaagaaatcctggggcctgaagctcaggcagatgaagcaggatgtacagtaaaagatgatgaatgcgagtcagatgcagaaaatgagcaaaaccatgatcctaatgttgaagagtttctacaacaacaagacactgctgtcatttttcctgaggcacctgaagaggaccagaggcagggcacaccagaagccagtggtcatgatgaaaatggaacaccagatgcattttcacaattactcacctgtccatattgtgatagaggctataaacgctttacctctctgaaagaacacattaaatatcgtcatgaaaagaatgaagataactttagttgctccctgtgcagttacacctttgcatacagaacccaacttgaacgtcacatgacatcacataaatcaggaagagatcaaagacatgtgacgcagtctgggtgtaatcgtaaattcaaatgcactgagtgtggaaaagctttcaaatacaaacatcacctaaaagagcacttaagaattcacagtggagagaagccatatgaatgcccaaactgcaagaaacgcttttcccattctggctcctatagctcacacataagcagtaagaaatgtatcagcttgatacctgtgaatgggcgaccaagaacaggactcaagacatctcagtgttcttcaccgtctctttcagcatcaccaggcagtcccacacgaccacagatacggcaaaagatagagaataaaccccttcaagaacaactttctgttaaccaaattaaaactgaacctgtggattatgaattcaaacccatagtggttgcttcaggaatcaactgttcaacccctttacaaaatggggttttcactggtggtggcccattacaggcaaccagttctcctcagggcatggtgcaagctgttgttctgccaacagttggtttggtgtctcccataagtatcaatttaagtgatattcagaatgtacttaaagtggcggtagatggtaatgtaataaggcaagtgttggagaataatcaagccaatcttgcatccaaagaacaagaaacaatcaatgcttcacccatacaacaaggtggccattctgttatttcagccatcagtcttcctttggttgatcaagatggaacaaccaaaattatcatcaactacagtcttgagcagcctagccaacttcaagttgttcctcaaaatttaaaaaaagaaaatccagtcgctacaaacagttgtaaaagtgaaaagttaccagaagatcttactgttaagtctgagaaggacaaaagctttgaagggggggtgaatgatagcacttgtcttctgtgtgatgattgtccaggagatattaatgcacttccagaattaaagcactatgacctaaagcagcctactcagcctcctccactccctgcagcagaagctgagaagcctgagtcctctgtttcatcagctactggagatggcaatttgtctcctagtcagccacctttaaagaacctcttgtctctcctaaaagcatattatgctttgaatgcacaaccaagtgcagaagagctctcaaaaattgctgattcagtaaacctaccactggatgtagtaaaaaagtggtttgaaaagatgcaagctggacagatttcagtgcagtcttctgaaccatcttctcctgaaccaggcaaagtaaatatccctgccaagaacaatgatcagcctcaatctgcaaatgcaaatgaaccccaggacagcacagtaaatctacaaagtcctttgaagatgactaactccccagttttaccagtgggatcaaccaccaatggttccagaagtagtacaccatccccatcacctctaaacctttcctcatccagaaatacacagggttacttgtacacagctgagggtgcacaagaagagccacaagtagaacctcttgatctttcactaccaaagcaacagggagaattattagaaaggtcaactatcactagtgtttaccagaacagtgtttattctgtccaggaagaacccttgaacttgtcttgcgcaaaaaaggagccacaaaaggacagttgtgttacagactcagaaccagttgtaaatgtaatcccaccaagtgccaaccccataaatatcgctatacctacagtcactgcccagttacccacaatcgtggccattgctgaccagaacagtgttccatgcttaagagcgctagctgccaataagcaaacgattctgattccccaggtggcatacacctactcaactacggtcagccctgcagtccaagaaccacccttgaaagtgatccagccaaatggaaatcaggatgaaagacaagatactagctcagaaggagtatcaaatgtagaggatcagaatgactctgattctacaccgcccaaaaagaaaatgcggaagacagaaaatggaatgtatgcttgtgatttgtgtgacaagatattccaaaagagtagttcattattgagacataaatatgaacacacaggtaaaagacctcatgagtgtggaatctgtaaaaaggcatttaaacacaaacatcatttgattgaacacatgcgattacattctggagaaaagccctatcaatgtgacaaatgtggaaagcgcttctcacactctgggtcttattctcaacacatgaatcatcgctactcctactgtaagagagaagcggaagaacgtgacagcacagagcaggaagaggcagggcctgaaatcctctcgaatgagcacgtgggtgccagggcgtctccctcacagggcgactcggacgagagagagagtttgacaagggaagaggatgaagacagtgaaaaagaggaagaggaggaggataaagagatggaagaattgcaggaagaaaaagaatgtgaaaaaccacaaggggatgaggaagaggaggaggaggaggaagaagtggaagaagaagaggtagaagaggcagagaatgagggagaagaagcaaaaactgaaggtctgatgaaggatgacagggctgaaagtcaagcaagcagcttaggacaaaaagtaggcgagagtagtgagcaagtgtctgaagaaaagacaaatgaagcctaatcgtttttctagaaggaaaataaattctaattgataatgaatttcgttcaatattatccttgcttttcatggaaacacagtaacctgtatgctgtgattcctgttcactactgtgtaaagtaaaaactaaaaaaatacaaaatacaaaacacacacacacacacacacacacacacacacacacacacaaaataaatccgggtgtgcctgaacctcagacctagtaatttttcatgcagttttcaaagttaggaacaagtttgtaacatgcagcagattagaaaaccttaatgactcagagagcaacaatacaagaggttaaaggaagctgattaattagatatgcatctggcattgttttatcttatcagtattatcactcttatgttggtttattcttaagctgtacaattgggagaaattttataattttttattggtaaacatatgctaaatccgcttcagtattttattatgttttttaaaatgtgagaacttctgcactacaaaattcccttcacagagaagtataatgtagttccaacccgtgctaactaccttttataaattcagtctagaaggtagtaatttctaatatttagatgtcttagtagagcgtattatcatttaaagtgtattgttagccttaagaaagcagctgatagaagaactgaagtttcttactcacgtggtttaaaatggagttcaaaagattgccattgagttctgattgcagggactaacaatgttaatctgataaggacagcaaaatcatcagaatcagtgtttgtgattgtgtttgaatatgtggtaacatatgaaggatatgacatgaagctttgtatctcctttggccttaagcaagacctgtgtgctgtaagtgccatttctcagtattttcaaggctctaacccgccttcatccaatgtgtggcctacaataactagcatttgttgatttgtctcttgtatcaaaattcccaaataaaacttaaaaccactgactctgtcagagaaactgaaacactgggacatttcatccttcaattcctcggtattgattttatgttgattgattttcagaatttctctacagaaacgaaagggaaattttctaatctgctttatccatgtacttgcatttcagacatggacatgctattgttatttggctcataactgtttccaaatgttagttattatggacccaatttattaacaacattagctgatttttacctatcagtattattttatttcttttagtttatagatctgtgcaacatttttgtactgtatgtcttcaaacctggcagtattaatacccttcttactgacatatgtacttttagttttagaaaacttttatatttatgtgtcttatttttatatttctttatttattacacagtgtagtgtataatactgtagtttgtattaatacaataatatattttagtatgaaaatttggaaagttgataagatttaaagtagagatgcaattggttctcctgcattgagatttgatttaacagtgttatgttaacatttatacttgccttggactgtagaacagaacttaaatgggaatgtattagttttacaactacaatcaagtcattttacctttacccagtttttaatataaaacttaaattttgaaattcactgtgtgactaatagcatgatgctctgcagttttattaagaaatcagcctaaccatacaactctcatttccttagtaagccaaattaggattaacttctataaacagtgttgggaacaatgtttaacattttgtgccaatttgttcctgtattcatgtatgtaagttacagatctgactcttcatttttaagttccttgttacatcatggtcattttctagttttttaccagactcccatctcacaataaaatgcatcaacaagcctgaactgctgtcattcttttcatcattatcagtattttctttggaaaactgtgaaatggggtacattgtcatcctgcatttgattcatcttgagctgaatttgggtaacactaaatgttttagacattctccactaaattatggattttcttgtggctaaatgtttctggagaggtcagagttgacaaaacctcttcacaggttgctccttcttcctgaaatccttaatcctccgcatttcatgcttcaggtcatttcagggaagcctgggtttagatgcctttctgactctcagctcctgcacttctgtcatcatacctctgatactattatttatattccttccccactaggaacaggaaccacatttgtcatagtcactctcacattcctcactgcctaacagggtgcctggcataagttgggacaacagatatttgttgaataaaaatataatttgcatgtttatggagctcagctatgttctcactttttttgcttctaattccagaatatatgttaaatgatctaataatttgattattttcttataagtcttattaaacactagtcataatagacacaataaattatgccttctttttctattgccttaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:6935 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA
            GeneID:6935 -> Molecular function: GO:0003690 [double-stranded DNA binding] evidence: IEA
            GeneID:6935 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:6935 -> Molecular function: GO:0003713 [transcription coactivator activity] evidence: TAS
            GeneID:6935 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: TAS
            GeneID:6935 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:6935 -> Molecular function: GO:0008134 [transcription factor binding] evidence: IEA
            GeneID:6935 -> Molecular function: GO:0008270 [zinc ion binding] evidence: TAS
            GeneID:6935 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:6935 -> Molecular function: GO:0070888 [E-box binding] evidence: ISS
            GeneID:6935 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:6935 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:6935 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: TAS
            GeneID:6935 -> Biological process: GO:0006955 [immune response] evidence: TAS
            GeneID:6935 -> Biological process: GO:0007389 [pattern specification process] evidence: IEA
            GeneID:6935 -> Biological process: GO:0008283 [cell proliferation] evidence: TAS
            GeneID:6935 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: IEA
            GeneID:6935 -> Biological process: GO:0010464 [regulation of mesenchymal cell proliferation] evidence: IEA
            GeneID:6935 -> Biological process: GO:0014823 [response to activity] evidence: IEA
            GeneID:6935 -> Biological process: GO:0017015 [regulation of transforming growth factor beta receptor signaling pathway] evidence: IEA
            GeneID:6935 -> Biological process: GO:0030857 [negative regulation of epithelial cell differentiation] evidence: IEA
            GeneID:6935 -> Biological process: GO:0030900 [forebrain development] evidence: IEA
            GeneID:6935 -> Biological process: GO:0031667 [response to nutrient levels] evidence: IEA
            GeneID:6935 -> Biological process: GO:0033081 [regulation of T cell differentiation in thymus] evidence: IEA
            GeneID:6935 -> Biological process: GO:0045666 [positive regulation of neuron differentiation] evidence: ISS
            GeneID:6935 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IDA
            GeneID:6935 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IMP
            GeneID:6935 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:6935 -> Biological process: GO:0048596 [embryonic camera-type eye morphogenesis] evidence: IEA
            GeneID:6935 -> Biological process: GO:0048704 [embryonic skeletal system morphogenesis] evidence: IEA
            GeneID:6935 -> Biological process: GO:0048752 [semicircular canal morphogenesis] evidence: IEA
            GeneID:6935 -> Biological process: GO:0051150 [regulation of smooth muscle cell differentiation] evidence: IEA
            GeneID:6935 -> Biological process: GO:0051216 [cartilage development] evidence: IEA
            GeneID:6935 -> Biological process: GO:0071230 [cellular response to amino acid stimulus] evidence: IEA
            GeneID:6935 -> Biological process: GO:0071560 [cellular response to transforming growth factor beta stimulus] evidence: IEA
            GeneID:6935 -> Biological process: GO:0090103 [cochlea morphogenesis] evidence: IEA
            GeneID:6935 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:6935 -> Cellular component: GO:0005667 [transcription factor complex] evidence: IEA
            GeneID:6935 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:6935 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA