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2025-05-09 20:10:30, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001135186 2111 bp mRNA linear PRI 15-JUN-2013
DEFINITION Homo sapiens ABI family, member 3 (ABI3), transcript variant 2,
mRNA.
ACCESSION NM_001135186
VERSION NM_001135186.1 GI:206597501
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2111)
AUTHORS Lauc,G., Huffman,J.E., Pucic,M., Zgaga,L., Adamczyk,B., Muzinic,A.,
Novokmet,M., Polasek,O., Gornik,O., Kristic,J., Keser,T.,
Vitart,V., Scheijen,B., Uh,H.W., Molokhia,M., Patrick,A.L.,
McKeigue,P., Kolcic,I., Lukic,I.K., Swann,O., van Leeuwen,F.N.,
Ruhaak,L.R., Houwing-Duistermaat,J.J., Slagboom,P.E., Beekman,M.,
de Craen,A.J., Deelder,A.M., Zeng,Q., Wang,W., Hastie,N.D.,
Gyllensten,U., Wilson,J.F., Wuhrer,M., Wright,A.F., Rudd,P.M.,
Hayward,C., Aulchenko,Y., Campbell,H. and Rudan,I.
TITLE Loci associated with N-glycosylation of human immunoglobulin G show
pleiotropy with autoimmune diseases and haematological cancers
JOURNAL PLoS Genet. 9 (1), E1003225 (2013)
PUBMED 23382691
REFERENCE 2 (bases 1 to 2111)
AUTHORS Latini,F.R., Hemerly,J.P., Freitas,B.C., Oler,G., Riggins,G.J. and
Cerutti,J.M.
TITLE ABI3 ectopic expression reduces in vitro and in vivo cell growth
properties while inducing senescence
JOURNAL BMC Cancer 11, 11 (2011)
PUBMED 21223585
REMARK GeneRIF: Result links ABI3 to the pathogenesis and progression of
some cancers and suggests that ABI3 or its pathway might have
interest as therapeutic target.
Publication Status: Online-Only
REFERENCE 3 (bases 1 to 2111)
AUTHORS Venkatesan,K., Rual,J.F., Vazquez,A., Stelzl,U., Lemmens,I.,
Hirozane-Kishikawa,T., Hao,T., Zenkner,M., Xin,X., Goh,K.I.,
Yildirim,M.A., Simonis,N., Heinzmann,K., Gebreab,F., Sahalie,J.M.,
Cevik,S., Simon,C., de Smet,A.S., Dann,E., Smolyar,A.,
Vinayagam,A., Yu,H., Szeto,D., Borick,H., Dricot,A., Klitgord,N.,
Murray,R.R., Lin,C., Lalowski,M., Timm,J., Rau,K., Boone,C.,
Braun,P., Cusick,M.E., Roth,F.P., Hill,D.E., Tavernier,J.,
Wanker,E.E., Barabasi,A.L. and Vidal,M.
TITLE An empirical framework for binary interactome mapping
JOURNAL Nat. Methods 6 (1), 83-90 (2009)
PUBMED 19060904
REFERENCE 4 (bases 1 to 2111)
AUTHORS Hirao,N., Sato,S., Gotoh,T., Maruoka,M., Suzuki,J., Matsuda,S.,
Shishido,T. and Tani,K.
TITLE NESH (Abi-3) is present in the Abi/WAVE complex but does not
promote c-Abl-mediated phosphorylation
JOURNAL FEBS Lett. 580 (27), 6464-6470 (2006)
PUBMED 17101133
REMARK GeneRIF: NESH (Abi-3), like Abi-1 and Abi-2, is a component of the
Abi/WAVE complex, but likely plays a different role in the
regulation of c-Abl.
REFERENCE 5 (bases 1 to 2111)
AUTHORS Ichigotani,Y., Fujii,K., Hamaguchi,M. and Matsuda,S.
TITLE In search of a function for the E3B1/Abi2/Argbp1/NESH family
(Review)
JOURNAL Int. J. Mol. Med. 9 (6), 591-595 (2002)
PUBMED 12011975
REMARK Review article
REFERENCE 6 (bases 1 to 2111)
AUTHORS Ichigotani,Y., Yokozaki,S., Fukuda,Y., Hamaguchi,M. and Matsuda,S.
TITLE Forced expression of NESH suppresses motility and metastatic
dissemination of malignant cells
JOURNAL Cancer Res. 62 (8), 2215-2219 (2002)
PUBMED 11956071
REMARK GeneRIF: Forced expression of NESH suppresses motility and
metastatic dissemination of malignant cells.
REFERENCE 7 (bases 1 to 2111)
AUTHORS Matsuda,S., Iriyama,C., Yokozaki,S., Ichigotani,Y., Shirafuji,N.,
Yamaki,K., Hayakawa,T. and Hamaguchi,M.
TITLE Cloning and sequencing of a novel human gene that encodes a
putative target protein of Nesh-SH3
JOURNAL J. Hum. Genet. 46 (8), 483-486 (2001)
PUBMED 11501947
REFERENCE 8 (bases 1 to 2111)
AUTHORS Miyazaki,K., Matsuda,S., Ichigotani,Y., Takenouchi,Y., Hayashi,K.,
Fukuda,Y., Nimura,Y. and Hamaguchi,M.
TITLE Isolation and characterization of a novel human gene (NESH) which
encodes a putative signaling molecule similar to e3B1 protein
JOURNAL Biochim. Biophys. Acta 1493 (1-2), 237-241 (2000)
PUBMED 10978530
REFERENCE 9 (bases 1 to 2111)
AUTHORS Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
Wiemann,S.
TITLE Systematic subcellular localization of novel proteins identified by
large-scale cDNA sequencing
JOURNAL EMBO Rep. 1 (3), 287-292 (2000)
PUBMED 11256614
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AB037886.1, BI768790.1 and
AA808681.1.
Summary: This gene encodes a member of an adaptor protein family.
Members of this family encode proteins containing a homeobox
homology domain, proline rich region and Src-homology 3 (SH3)
domain, and are components of the Abi/WAVE complex which regulates
Rac-dependent actin polymerization. The encoded protein inhibits
ectopic metastasis of tumor cells as well as cell migration. This
may be accomplished through interaction with p21-activated kinase.
[provided by RefSeq, Sep 2008].
Transcript Variant: This variant (2) uses an alternate in-frame
splice site in the 5' coding region, compared to variant 1,
resulting in a shorter protein (isoform 2).
##Evidence-Data-START##
RNAseq introns :: mixed/partial sample support ERS025081, ERS025084
[ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-493 AB037886.1 1-493
494-1195 BI768790.1 1-702
1196-2090 AB037886.1 1214-2108
2091-2111 AA808681.1 4-24 c
FEATURES Location/Qualifiers
source 1..2111
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21.3"
gene 1..2111
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/note="ABI family, member 3"
/db_xref="GeneID:51225"
/db_xref="HGNC:29859"
/db_xref="MIM:606363"
exon 1..615
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 63
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:2233364"
misc_feature 94..96
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/note="upstream in-frame stop codon"
variation 94
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149838793"
variation 107
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="c"
/db_xref="dbSNP:12948271"
variation 250..261
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace=""
/replace="tgggcccccaaa"
/db_xref="dbSNP:140527653"
variation 344
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:73338394"
variation 387
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="g"
/replace="t"
/db_xref="dbSNP:188837768"
variation 388
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="g"
/db_xref="dbSNP:377689573"
variation 445
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="g"
/db_xref="dbSNP:192806498"
variation 464
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2233365"
CDS 499..1581
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/note="isoform 2 is encoded by transcript variant 2; ABI
gene family, member 3; new molecule including SH3; ABI
gene family member 3"
/codon_start=1
/product="ABI gene family member 3 isoform 2"
/protein_id="NP_001128658.1"
/db_xref="GI:206597502"
/db_xref="CCDS:CCDS45725.1"
/db_xref="GeneID:51225"
/db_xref="HGNC:29859"
/db_xref="MIM:606363"
/translation="
MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARMVNMHMEKVARREIGTLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC
"
misc_feature 760..978
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/note="Abl-interactor HHR; Region: Abi_HHR; pfam07815"
/db_xref="CDD:149081"
misc_feature 1414..1569
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/note="Src homology 3 domain of Abl Interactor proteins;
Region: SH3_Abi; cd11826"
/db_xref="CDD:212760"
misc_feature order(1429..1431,1435..1437,1444..1446,1456..1458,
1510..1515,1552..1554,1558..1563)
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/note="peptide ligand binding site [polypeptide binding];
other site"
/db_xref="CDD:212760"
variation 511
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:143414853"
variation 544
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370923583"
variation 564
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:376299895"
variation 574
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="c"
/db_xref="dbSNP:201115503"
variation 598
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146754613"
exon 616..765
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 628
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200790496"
variation 629
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2233369"
variation 635
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:143540619"
variation 649
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143614623"
variation 652
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200111501"
variation 707
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:371444697"
variation 723
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201757928"
variation 742
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:374915787"
variation 755
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="g"
/replace="t"
/db_xref="dbSNP:199999962"
variation 759
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:35031462"
variation 763
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:369657954"
exon 766..942
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 770
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:202087269"
variation 776
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377358127"
variation 795
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:145273532"
variation 813
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:117896869"
variation 820
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:187673177"
variation 823
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="g"
/db_xref="dbSNP:201557264"
variation 827
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142527437"
variation 830
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:137924898"
variation 850
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:139297199"
variation 937
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:370412209"
exon 943..1028
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 972
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:73340306"
variation 1002
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:2233371"
exon 1029..1124
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 1103
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:199635084"
variation 1106
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:616338"
exon 1125..1282
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 1125
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:147987389"
variation 1131
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="c"
/db_xref="dbSNP:76617033"
variation 1141
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200867869"
variation 1146
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:376591517"
variation 1156
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150532080"
variation 1162
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:369790283"
variation 1192
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139539456"
variation 1199
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:368043560"
variation 1211
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="c"
/db_xref="dbSNP:371508417"
variation 1230
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="c"
/db_xref="dbSNP:375202610"
variation 1251
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="g"
/db_xref="dbSNP:141746983"
exon 1283..1417
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 1284
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:146244763"
variation 1285
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200803220"
variation 1308
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371106947"
variation 1318
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139368451"
variation 1324
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="c"
/db_xref="dbSNP:144160707"
variation 1331
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="t"
/db_xref="dbSNP:145120343"
variation 1339
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199538050"
variation 1399
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="g"
/replace="t"
/db_xref="dbSNP:373253578"
variation 1408
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="g"
/replace="t"
/db_xref="dbSNP:377169529"
variation 1410
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="g"
/db_xref="dbSNP:370459926"
exon 1418..2091
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/inference="alignment:Splign:1.39.8"
variation 1423
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:150100821"
variation 1434
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142832429"
variation 1496
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201030368"
variation 1506
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:151062169"
variation 1524
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:368794979"
variation 1525
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200202572"
variation 1585
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="g"
/db_xref="dbSNP:2233374"
variation 1606
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="g"
/replace="t"
/db_xref="dbSNP:368644987"
variation 1616
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371956623"
variation 1900
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:114842800"
variation 1903
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="g"
/db_xref="dbSNP:187442799"
variation 1928
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="c"
/db_xref="dbSNP:191319602"
variation 1973..1974
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace=""
/replace="c"
/db_xref="dbSNP:34526681"
variation 1975
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:183237512"
variation 1977
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="c"
/replace="t"
/db_xref="dbSNP:11545136"
variation 2059
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/replace="a"
/replace="g"
/db_xref="dbSNP:56327802"
polyA_site 2091
/gene="ABI3"
/gene_synonym="NESH; SSH3BP3"
/experiment="experimental evidence, no additional details
recorded"
ORIGIN
tcctatccaccctccactcccctgtcccttggtgactcatccctgagcttcccaaggaagcccccaccctctgccctttcctcccgccttccatgagtggaaaatccacctccgccccctatagcaggccagcccccttcctccccagtctccgaccccatcccccagccgaccagtttcctctccaggaccagggagcaatcacagctgccccgaccttggcttcctctgctgggtgggattgggggctgggcccccaaatgggcccctggcttcccccttcctctgggcaggggacagagagacacaggctcggggagcaggactgacttcctcttgtcccggaatgagcatgcctgccctttgcaagcaggtttgggtctcacgcagaggaaaccaaaagcaataagagggagggaaggcagagcaaccaatcaagggcagggtgagactcaaaacgagcgggctccctggggagccagacagaggctgggggtgatggcggagctacagcagctgcaggagtttgagatccccactggccgggaggctctgaggggcaaccacagtgccctgctgcgggtcgctgactactgcgaggacaactatgtgcaggccacagacaagcggaaggcgctggaggagaccatggccttcactacccaggcactggccagcgtggcctaccaggtgggcaacctggccgggcacactctgcgcatgttggacctgcagggggccgccctgcggcaggtggaagcccgtatggtgaacatgcatatggagaaggtggcccgaagggagatcggcaccttagccactgtccagcggctgccccccggccagaaggtcatcgccccagagaacctaccccctctcacgccctactgcaggagacccctcaactttggctgcctggacgacattggccatgggatcaaggacctcagcacgcagctgtcaagaacaggcaccctgtctcgaaagagcatcaaggcccctgccacacccgcctccgccaccttggggagaccaccccggattcccgagccagtgcacctgccggtggtgcccgacggcagactctccgccgcctcctctgcgtcttccctggcctcggccggcagcgccgaaggtgtcggtggggcccccacgcccaaggggcaggcagcacctccagccccacctctccccagctccttggacccacctcctccaccagcagccgtcgaggtgttccagcggcctcccacgctggaggagttgtccccacccccaccggacgaagagctgcccctgccactggacctgcctcctcctccacccctggatggagatgaattggggctgcctccacccccaccaggatttgggcctgatgagcccagctgggtgcctgcctcatacttggagaaagtggtgacactgtacccatacaccagccagaaggacaatgagctctccttctctgagggcactgtcatctgtgtcactcgccgctactccgatggctggtgcgagggcgtcagctcagaggggactggattcttccctgggaactatgtggagcccagctgctgacagcccagggctctctgggcagctgatgtctgcactgagtgggtttcatgagccccaagccaaaaccagctccagtcacagctggactgggtctgcccacctcttgggctgtgagctgtgttctgtccttcctcccatcggagggagaaggggtcctggggagagagaatttatccagaggcctgctgcagatggggaagagctggaaaccaagaagtttgtcaacagaggacccctactccatgcaggacagggtctcctgctgcaagtcccaactttgaataaaacagatgatgtcctgtgactgccccacagagataaggggccaggagggattgaaaggcatcccagttctaaggctgctgctaattacagcccccaacctccaacccaccagctgacctagaagcagcatcttcccatttcctcagtacccacaaagtgcagcccacattggaccccagacacccctctgcagccattgactgcaacttgttcttttgcccattgaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:51225 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:51225 -> Biological process: GO:0006928 [cellular component movement] evidence: NAS
GeneID:51225 -> Biological process: GO:0018108 [peptidyl-tyrosine phosphorylation] evidence: IDA
GeneID:51225 -> Biological process: GO:0030334 [regulation of cell migration] evidence: IDA
GeneID:51225 -> Cellular component: GO:0005622 [intracellular] evidence: IDA
GeneID:51225 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:51225 -> Cellular component: GO:0005737 [cytoplasm] evidence: NAS
GeneID:51225 -> Cellular component: GO:0030027 [lamellipodium] evidence: IDA
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DBCLS
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