LOCUS       NM_000554               4482 bp    mRNA    linear   PRI 13-APR-2013
DEFINITION  Homo sapiens cone-rod homeobox (CRX), mRNA.
ACCESSION   NM_000554
VERSION     NM_000554.4  GI:189095267
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4482)
  AUTHORS   Huang,L., Xiao,X., Li,S., Jia,X., Wang,P., Guo,X. and Zhang,Q.
  TITLE     CRX variants in cone-rod dystrophy and mutation overview
  JOURNAL   Biochem. Biophys. Res. Commun. 426 (4), 498-503 (2012)
   PUBMED   22960069
  REMARK    GeneRIF: In this study, three variations were detected in 3 of 130
            families with CORD, including two novel mutations, c.239A>G
            (p.Glu80Gly) and c.362C>T (p.Ala121Val)
REFERENCE   2  (bases 1 to 4482)
  AUTHORS   Terry,J., Calicchio,M.L., Rodriguez-Galindo,C. and
            Perez-Atayde,A.R.
  TITLE     Immunohistochemical expression of CRX in extracranial malignant
            small round cell tumors
  JOURNAL   Am. J. Surg. Pathol. 36 (8), 1165-1169 (2012)
   PUBMED   22790857
  REMARK    GeneRIF: These findings suggest that CRX is a useful marker to
            discriminate metastatic retinoblastoma from other, more common,
            malignant small round cell tumors of childhood
REFERENCE   3  (bases 1 to 4482)
  AUTHORS   Seko,Y., Azuma,N., Kaneda,M., Nakatani,K., Miyagawa,Y., Noshiro,Y.,
            Kurokawa,R., Okano,H. and Umezawa,A.
  TITLE     Derivation of human differential photoreceptor-like cells from the
            iris by defined combinations of CRX, RX and NEUROD
  JOURNAL   PLoS ONE 7 (4), E35611 (2012)
   PUBMED   22558175
  REMARK    GeneRIF: Photosensitive photoreceptor cells can be generated by
            combinations of transcription factors. The combination of CRX and
            RX generate immature photoreceptors: and additional NEUROD promotes
            maturation.
REFERENCE   4  (bases 1 to 4482)
  AUTHORS   Booij,J.C., Bakker,A., Kulumbetova,J., Moutaoukil,Y., Smeets,B.,
            Verheij,J., Kroes,H.Y., Klaver,C.C., van Schooneveld,M.,
            Bergen,A.A. and Florijn,R.J.
  TITLE     Simultaneous mutation detection in 90 retinal disease genes in
            multiple patients using a custom-designed 300-kb retinal
            resequencing chip
  JOURNAL   Ophthalmology 118 (1), 160-167 (2011)
   PUBMED   20801516
  REMARK    GeneRIF: Observational study of genetic testing. (HuGE Navigator)
REFERENCE   5  (bases 1 to 4482)
  AUTHORS   Huang,Y., Cai,M., Clore,G.M. and Craigie,R.
  TITLE     No interaction of barrier-to-autointegration factor (BAF) with
            HIV-1 MA, cone-rod homeobox (Crx) or MAN1-C in absence of DNA
  JOURNAL   PLoS ONE 6 (9), E25123 (2011)
   PUBMED   21966431
  REMARK    GeneRIF: Data show no interaction of barrier-to-autointegration
            factor (BAF) with HIV-1 MA, cone-rod homeobox (Crx) or MAN1-C in
            absence of DNA.
REFERENCE   6  (bases 1 to 4482)
  AUTHORS   Sohocki,M.M., Sullivan,L.S., Mintz-Hittner,H.A., Birch,D.,
            Heckenlively,J.R., Freund,C.L., McInnes,R.R. and Daiger,S.P.
  TITLE     A range of clinical phenotypes associated with mutations in CRX, a
            photoreceptor transcription-factor gene
  JOURNAL   Am. J. Hum. Genet. 63 (5), 1307-1315 (1998)
   PUBMED   9792858
REFERENCE   7  (bases 1 to 4482)
  AUTHORS   Freund,C.L., Wang,Q.L., Chen,S., Muskat,B.L., Wiles,C.D.,
            Sheffield,V.C., Jacobson,S.G., McInnes,R.R., Zack,D.J. and
            Stone,E.M.
  TITLE     De novo mutations in the CRX homeobox gene associated with Leber
            congenital amaurosis
  JOURNAL   Nat. Genet. 18 (4), 311-312 (1998)
   PUBMED   9537410
REFERENCE   8  (bases 1 to 4482)
  AUTHORS   Swain,P.K., Chen,S., Wang,Q.L., Affatigato,L.M., Coats,C.L.,
            Brady,K.D., Fishman,G.A., Jacobson,S.G., Swaroop,A., Stone,E.,
            Sieving,P.A. and Zack,D.J.
  TITLE     Mutations in the cone-rod homeobox gene are associated with the
            cone-rod dystrophy photoreceptor degeneration
  JOURNAL   Neuron 19 (6), 1329-1336 (1997)
   PUBMED   9427255
REFERENCE   9  (bases 1 to 4482)
  AUTHORS   Freund,C.L., Gregory-Evans,C.Y., Furukawa,T., Papaioannou,M.,
            Looser,J., Ploder,L., Bellingham,J., Ng,D., Herbrick,J.A.,
            Duncan,A., Scherer,S.W., Tsui,L.C., Loutradis-Anagnostou,A.,
            Jacobson,S.G., Cepko,C.L., Bhattacharya,S.S. and McInnes,R.R.
  TITLE     Cone-rod dystrophy due to mutations in a novel
            photoreceptor-specific homeobox gene (CRX) essential for
            maintenance of the photoreceptor
  JOURNAL   Cell 91 (4), 543-553 (1997)
   PUBMED   9390563
REFERENCE   10 (bases 1 to 4482)
  AUTHORS   Evans,K., Fryer,A., Inglehearn,C., Duvall-Young,J., Whittaker,J.L.,
            Gregory,C.Y., Butler,R., Ebenezer,N., Hunt,D.M. and Bhattacharya,S.
  TITLE     Genetic linkage of cone-rod retinal dystrophy to chromosome 19q and
            evidence for segregation distortion
  JOURNAL   Nat. Genet. 6 (2), 210-213 (1994)
   PUBMED   8162077
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL711350.1, BT007364.1,
            AF335249.1, AC008745.7 and BU736672.1.
            This sequence is a reference standard in the RefSeqGene project.
            On May 28, 2008 this sequence version replaced gi:87196337.
            
            Summary: The protein encoded by this gene is a
            photoreceptor-specific transcription factor which plays a role in
            the differentiation of photoreceptor cells. This homeodomain
            protein is necessary for the maintenance of normal cone and rod
            function. Mutations in this gene are associated with photoreceptor
            degeneration, Leber congenital amaurosis type III and the autosomal
            dominant cone-rod dystrophy 2. Several alternatively spliced
            transcript variants of this gene have been described, but the
            full-length nature of some variants has not been determined.
            [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AL711350.1, BC016664.1 [ECO:0000332]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-565               AL711350.1         1-565
            566-1104            BT007364.1         362-900
            1105-1872           AF335249.1         1-768
            1873-1874           AC008745.7         120950-120951
            1875-2225           AF335249.1         771-1121
            2226-2227           AC008745.7         121303-121304
            2228-4466           AF335249.1         1124-3362
            4467-4482           BU736672.1         1-16                c
FEATURES             Location/Qualifiers
     source          1..4482
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.3"
     gene            1..4482
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /note="cone-rod homeobox"
                     /db_xref="GeneID:1406"
                     /db_xref="HGNC:2383"
                     /db_xref="HPRD:03748"
                     /db_xref="MIM:602225"
     exon            1..169
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /inference="alignment:Splign:1.39.8"
     variation       30
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142297785"
     variation       81
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:190144153"
     variation       89
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10418215"
     variation       119
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193162118"
     misc_feature    127..129
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /note="upstream in-frame stop codon"
     exon            170..304
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /inference="alignment:Splign:1.39.8"
     STS             173..421
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="Crx"
                     /db_xref="UniSTS:536452"
     variation       197
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371111993"
     variation       198
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200832191"
     CDS             205..1104
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /note="orthodenticle homeobox 3"
                     /codon_start=1
                     /product="cone-rod homeobox protein"
                     /protein_id="NP_000545.1"
                     /db_xref="GI:4557489"
                     /db_xref="CCDS:CCDS12706.1"
                     /db_xref="GeneID:1406"
                     /db_xref="HGNC:2383"
                     /db_xref="HPRD:03748"
                     /db_xref="MIM:602225"
                     /translation="

MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL

"
     misc_feature    322..486
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:28970"
     misc_feature    order(322..336,340..342,391..393,409..411,448..450,
                     454..459,466..471,475..483)
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:28970"
     misc_feature    order(328..330,337..339,457..459,466..471,478..480)
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:28970"
     STS             205..1104
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="Crx"
                     /db_xref="UniSTS:546710"
     variation       213
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140766502"
     variation       214
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150122798"
     variation       217
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145337312"
     variation       225..226
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:62636512"
     variation       226
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146240568"
     variation       232
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139340178"
     exon            305..456
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /inference="alignment:Splign:1.39.8"
     variation       306
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139778328"
     variation       311
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:193920917"
     variation       325
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:104894672"
     variation       326
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748436"
     variation       327
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181068147"
     variation       342
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199607129"
     variation       370
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748437"
     variation       382
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370973957"
     variation       400
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748438"
     variation       407
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145649717"
     variation       417
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185420673"
     variation       442
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:62654391"
     variation       443
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:104894671"
     exon            457..4467
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /inference="alignment:Splign:1.39.8"
     variation       472
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:104894673"
     variation       497
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372219374"
     variation       513
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138242846"
     variation       539
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61748439"
     variation       555..556
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:61748440"
     variation       566
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371847743"
     variation       567
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141888455"
     variation       569
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748441"
     variation       572
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201969424"
     variation       573
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368752695"
     variation       616
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373934471"
     variation       619
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373281561"
     variation       629
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748442"
     variation       637
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149300196"
     variation       640..651
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="ctgcccggcccc"
                     /db_xref="dbSNP:281865202"
     variation       645
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147422878"
     variation       648..649
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:61748444"
     variation       675
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:111549777"
     variation       676
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748445"
     variation       705..706
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="ag"
                     /db_xref="dbSNP:61748446"
     variation       709
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:61748447"
     variation       724
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:281865515"
     variation       726
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376827106"
     variation       733
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:61748449"
     variation       736
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369142479"
     variation       745
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:61748450"
     variation       753
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748451"
     variation       755
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147558800"
     variation       759
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:374770860"
     variation       768
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148622001"
     variation       769
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142111462"
     variation       772
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151169551"
     variation       775
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:61748452"
     variation       789..790
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:61748453"
     variation       789
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373497612"
     variation       791..794
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="cccc"
                     /db_xref="dbSNP:61748454"
     variation       801
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61748455"
     variation       819
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:281865516"
     variation       822
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145117150"
     variation       823
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376982187"
     variation       849
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191794330"
     variation       853
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146869548"
     variation       854
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:281865517"
     variation       913
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:281865518"
     variation       928
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748459"
     variation       930
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371406142"
     variation       957
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:61749660"
     variation       969
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145913500"
     variation       981
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373752882"
     variation       982
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370592248"
     variation       993
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:281865519"
     variation       994
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138146799"
     variation       1022
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:281865203"
     variation       1041
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201875881"
     variation       1109
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371493617"
     variation       1110
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375770558"
     variation       1119
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369336775"
     variation       1120
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371964860"
     variation       1123
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79186398"
     variation       1131
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375168206"
     variation       1136
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146699567"
     variation       1138
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373098327"
     variation       1228
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:184746132"
     variation       1340
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:4133100"
     variation       1412..1414
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="aag"
                     /db_xref="dbSNP:5828321"
     variation       1412
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="aag"
                     /db_xref="dbSNP:34608204"
     variation       1416..1418
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="aga"
                     /db_xref="dbSNP:3859429"
     variation       1419..1421
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="agt"
                     /db_xref="dbSNP:201469714"
     variation       1461
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140211833"
     variation       1504..1505
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="aa"
                     /replace="tc"
                     /db_xref="dbSNP:70954417"
     variation       1504
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:3848536"
     variation       1505
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3848537"
     variation       1526
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370023906"
     variation       1535
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145243336"
     variation       1540
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:200074259"
     variation       1631
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371749408"
     STS             1634..1738
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="D8S2278"
                     /db_xref="UniSTS:473906"
     STS             1642..1733
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="D8S2279"
                     /db_xref="UniSTS:473907"
     variation       1683
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4356586"
     variation       1695
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3859430"
     variation       1699
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111448395"
     variation       1708
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150175309"
     STS             1715..2128
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="D11S3114"
                     /db_xref="UniSTS:152207"
     variation       1741
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372726992"
     variation       1783
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112202398"
     variation       1786
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3859431"
     variation       1786
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372476559"
     variation       1840..1841
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="tt"
                     /replace="ttt"
                     /db_xref="dbSNP:371206107"
     variation       1860..1861
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="ttt"
                     /db_xref="dbSNP:60558029"
     variation       1873
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:55835533"
     variation       1964
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185098538"
     variation       2070
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3933489"
     variation       2076
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:12462416"
     STS             2108..3479
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="GDB:631813"
                     /db_xref="UniSTS:158430"
     STS             2145..2254
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="G27385"
                     /db_xref="UniSTS:8722"
     variation       2150
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:62128808"
     variation       2167
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143939023"
     variation       2221
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147243365"
     variation       2226
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:73576710"
     variation       2252
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139073763"
     variation       2324
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:58323327"
     variation       2393
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:62128809"
     variation       2450
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12462534"
     variation       2559
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:10418834"
     variation       2707
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:149514395"
     variation       2727..2728
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:59559801"
     variation       2729
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200629088"
     variation       2754..2755
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:138321430"
     variation       2788
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141564522"
     variation       2838
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150910539"
     variation       2896
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:56226622"
     variation       2990
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372298545"
     variation       2995
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:35850082"
     variation       3065
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:117186518"
     variation       3097..3098
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:36012288"
     variation       3121
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73038753"
     variation       3143
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189556251"
     variation       3144
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139340702"
     variation       3210
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12982537"
     variation       3241
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181823708"
     variation       3259
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113560570"
     variation       3275
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77875912"
     variation       3287
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7259671"
     variation       3403
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73038757"
     variation       3421
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374041145"
     variation       3440
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185456543"
     variation       3479
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188212480"
     variation       3484
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:62128810"
     variation       3500
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374128749"
     variation       3591
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376730350"
     variation       3643
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146417527"
     variation       3663
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:12463238"
     variation       3714
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371836526"
     STS             3800..3978
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /standard_name="G42186"
                     /db_xref="UniSTS:105104"
     variation       3808
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12974951"
     variation       3821
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11666203"
     variation       3843
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149039830"
     variation       3862
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:117717088"
     variation       3875..3876
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:35378098"
     variation       3964
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:181436261"
     variation       3984
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142202442"
     variation       4041
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7248427"
     variation       4118
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186373883"
     variation       4121
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11666244"
     variation       4122
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375943096"
     variation       4221
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116336713"
     variation       4274
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151224936"
     variation       4342
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4081725"
     variation       4383
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11666316"
     variation       4389
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:62128811"
     variation       4405
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11670620"
     polyA_signal    4443..4448
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
     polyA_site      4467
                     /gene="CRX"
                     /gene_synonym="CORD2; CRD; LCA7; OTX3"
ORIGIN      

accttggccgggattaccctccgagttccaggccatgacaaatgacatcactcccggcccaggcttaaaatctccccatgtgaggggatgtgtttccttcagcctctgctgtctggccgctctgtctaggtcctgggccacgggagagccccgtccctcctttctgaaggccccctgacttgggcctcagtgtccccgaagatcatgatggcgtatatgaacccggggccccactattctgtcaacgccttggccctaagtggccccagtgtggatctgatgcaccaggctgtgccctacccaagcgcccccaggaagcagcggcgggagcgcaccaccttcacccggagccaactggaggagctggaggcactgtttgccaagacccagtacccagacgtctatgcccgtgaggaggtggctctgaagatcaatctgcctgagtccagggttcaggtttggttcaagaaccggagggctaaatgcaggcagcagcgacagcagcagaaacagcagcagcagcccccagggggccaggccaaggcccggcctgccaagaggaaggcgggcacgtccccaagaccctccacagatgtgtgtccagaccctctgggcatctcagattcctacagtccccctctgcccggcccctcaggctccccaaccacggcagtggccactgtgtccatctggagcccagcctcagagtcccctttgcctgaggcgcagcgggctgggctggtggcctcagggccgtctctgacctccgccccctatgccatgacctacgccccggcctccgctttctgctcttccccctccgcctatgggtctccgagctcctatttcagcggcctagacccctacctttctcccatggtgccccagctagggggcccggctcttagccccctctctggcccctccgtgggaccttccctggcccagtcccccacctccctatcaggccagagctatggcgcctacagccccgtggatagcttggaattcaaggaccccacgggcacctggaaattcacctacaatcccatggaccctctggactacaaggatcagagtgcctggaagtttcagatcttgtagaggacgcagtctccatctctctccatcgggcctcgggaccctttctcttctgaatctgcttccctgcagtttagatcccgggatggcattcctgagaaagcaacccgaaccagctgtccttctgacagctcggtgttcagcttacagagaccacccctttcctccacagggagaggctcctccctctcctgggacagctcacaggtcctagtgattctctcaaccctaacaccgtctggcacgattgtgaccgctgaagtacaccacgagctccaggcttcagaaagtggtgctgagaacttgctccaagaagaagtcaaaccaaacttgcagttgatttggggtcatgtttaggtcagaatcaccgtgcccttgaacaagcaggtaggggggcttgataacttaactttccacgtggacagaatttttttttttgttttgtttttgttttgcagacacagtctagctctgtcgcccaggctggagtgcagtggcacgatctcagctcactgcaagctctacctcccgggttcacgccattctcctgcctcagcctcccgagtagctgggactacagatgcccaccaccaggcccggctaattttttttgtatttttagtagagacggggtttcaccgtgttagccaggatggtctcgatctcctgacctcgtgatccgcccgcctcggcctcccaaagtgctaggattacaggcgtgagccaccgcgcccggcccttttttttttttttttttttaattgagacggagtctcactcttttgcttaggctggagtgcagtggtgtgatctcagctcactgactgcaacctccacctcccgggttgaagcgttgctcctgcctcaatctcccaattagctgggattacaggtgtgctccatcatgcccggctaatttttctattattagtagagacagggttttaccatgttggccaggctggtctggaacccctgacctcaagtgatccgcctgcctcggcctcccaaagtgctgggattacaggcatgagccattgtgcctggccctacacgtggacacttctttagcatatggttagggacctttctagaaattccaaagacagactttaagaagccccgtcgggaaaccttaggccaatgatgtggttacattaaaaataaattatctgggaatttcacagacttcacaaatgtcaggcttacatggtaggtttaggggaccgtttgagagacaaagatctacattcatatatgtagctatacatatatgtactttttcttcttagtttctttttaaagacattttatcactcattcgctcattagcacattgggaatgtgtgtatttggtagggaaatgaaaggcaccttgcctgttccatctctactccttttttcttttgttttaggattttctaaaggtgagacactggtggaactggggtagctgcttgggacgtaccacctatagttgtggctatttcacagagaagcagcagctagacagactcccatctgtaaataaacaagagataggaagagggggaaatagatttggaggaggcagccctacatttcaaacatacattcccttttttagatttttttttttttttttttggttttcagttttgatggtgggattggaaaatagagcttggcttgaggacattttcctggggtggcaccattatttcttgaaatagaatcttacttatggtgacactggcaagcacttgtgagaacctgaagacggattgaggtcatttgatgctcagaagttgggtgctgggtccctgccttctcagtccgagttctcctttcatttttgggtggggaggcgggttccaagagcccttcattggtggagttcacaaggcaaggtgtaaaaaaaaaagtagggcaggaagacagtggtgtgctggcagaggtctaacaatgggctctccaaggaagaggaaaaggttggttgtggagtgtttgtcagtttccgtggtgtaaatactcccaccacggctgacttcaagctagcaaccggaggtcactgaactaagagttgggaagagatagggcacaatatatgcttacgagttggtacacaccgtcagcagcagccagggtcaggagaaaggcgagatgtgaagagaggccgggaggtatcagatgacgtttccagcactagaccagaagaggtgcacacagcctagaccccctgaggggtacaccctgatctctagagcccacaaagaggtttttattcaacataaaacgtgttcatctctcataggcctgagtcatgctgggttctgggacattaagcccaggagtgggccgggtgcggtggctcacgcctgtaatcccagcactttgggaggccgaggcgggtggatcacctgaggtcaggagttcgagaccagcctggccaacatggtgaaaccctgtctctactaataatacaaaaattagccgggcatggtggcacgcgcctgtaatcccagctactcgggaggctgaggcaggagaattgctggaacccgggaggcggaggttgaagagagcagagattgtgccactgtgctctagcctgggtcacaagagcgaaactccgtctcaataataacaacaacaaaaataacccaggagtggctcaagagtccagtgtgggatgaaaatataaacagaggaagacaacatatgtcactggggaggctgggggagctagacaaaattcacacgggaggggcagggatgagacaatattgtgccctgggtctgtgcaaacgttgggaccagaatccactataagtttcattcttcggagacacggaagctctgcactggaggccgggactcaggcgtggaagagaatcttctccttattcaccggggaggctgtgtcttgtgcaaacaagtcatagaaacttgatgggagttggggagggactgaaggatgcatgcaaggttctgggaaggagtgagaagtagtgaaggccaaggggcccccatcacaggccgatggggtaagacttcgagagagcctgatcctggggtcttctgagactccaccaggagccggagagggcagggagccaaatccagctaggaggttacagattgcttttcctgggctgggctcctgagtgttggttcttccagctgtgcacaggggatttcaaacgttctacgtcctaaagccaggaagagtgacaaggcaggtggggacagaaggaagaagccaggagcctccctgagaaggtgtcaccttatctgtcctcctcttccccacacactggcctctgggtcccccttctctgtccacccacagagtgaaaccaattaaaatgttggatctcatttaaaaaaaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:1406 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA
            GeneID:1406 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:1406 -> Molecular function: GO:0043522 [leucine zipper domain binding] evidence: IPI
            GeneID:1406 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:1406 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:1406 -> Biological process: GO:0007601 [visual perception] evidence: IEA
            GeneID:1406 -> Biological process: GO:0009887 [organ morphogenesis] evidence: TAS
            GeneID:1406 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:1406 -> Biological process: GO:0050896 [response to stimulus] evidence: IEA
            GeneID:1406 -> Biological process: GO:0060041 [retina development in camera-type eye] evidence: IEA
            GeneID:1406 -> Cellular component: GO:0005667 [transcription factor complex] evidence: IEA