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2025-05-09 19:21:37, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_031423 1843 bp mRNA linear PRI 05-JUL-2013
DEFINITION Homo sapiens NUF2, NDC80 kinetochore complex component (NUF2),
transcript variant 2, mRNA.
ACCESSION NM_031423
VERSION NM_031423.3 GI:117968352
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1843)
AUTHORS Sethi,G., Pathak,H.B., Zhang,H., Zhou,Y., Einarson,M.B.,
Vathipadiekal,V., Gunewardena,S., Birrer,M.J. and Godwin,A.K.
TITLE An RNA interference lethality screen of the human druggable genome
to identify molecular vulnerabilities in epithelial ovarian cancer
JOURNAL PLoS ONE 7 (10), E47086 (2012)
PUBMED 23056589
REMARK GeneRIF: NDC80, NUF2 and PTN were significantly aberrantly
overexpressed in serous adenocarcinomas.
REFERENCE 2 (bases 1 to 1843)
AUTHORS Sundin,L.J., Guimaraes,G.J. and Deluca,J.G.
TITLE The NDC80 complex proteins Nuf2 and Hec1 make distinct
contributions to kinetochore-microtubule attachment in mitosis
JOURNAL Mol. Biol. Cell 22 (6), 759-768 (2011)
PUBMED 21270439
REMARK GeneRIF: These data suggest that the CH and tail domains of Hec1
generate essential contacts between kinetochores and microtubules
in cells, whereas the Nuf2 CH domain does not.
REFERENCE 3 (bases 1 to 1843)
AUTHORS Olson,J.E., Wang,X., Pankratz,V.S., Fredericksen,Z.S., Vachon,C.M.,
Vierkant,R.A., Cerhan,J.R. and Couch,F.J.
TITLE Centrosome-related genes, genetic variation, and risk of breast
cancer
JOURNAL Breast Cancer Res. Treat. 125 (1), 221-228 (2011)
PUBMED 20508983
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 4 (bases 1 to 1843)
AUTHORS Kaneko,N., Miura,K., Gu,Z., Karasawa,H., Ohnuma,S., Sasaki,H.,
Tsukamoto,N., Yokoyama,S., Yamamura,A., Nagase,H., Shibata,C.,
Sasaki,I. and Horii,A.
TITLE siRNA-mediated knockdown against CDCA1 and KNTC2, both frequently
overexpressed in colorectal and gastric cancers, suppresses cell
proliferation and induces apoptosis
JOURNAL Biochem. Biophys. Res. Commun. 390 (4), 1235-1240 (2009)
PUBMED 19878654
REMARK GeneRIF: cell growths of colorectal and gastric cancers after the
siRNA-mediated knockdown of either CDCA1 or KNTC2 were
significantly suppressed.
REFERENCE 5 (bases 1 to 1843)
AUTHORS Ehret,G.B., O'Connor,A.A., Weder,A., Cooper,R.S. and Chakravarti,A.
TITLE Follow-up of a major linkage peak on chromosome 1 reveals
suggestive QTLs associated with essential hypertension: GenNet
study
JOURNAL Eur. J. Hum. Genet. 17 (12), 1650-1657 (2009)
PUBMED 19536175
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 1843)
AUTHORS Tien,A.C., Lin,M.H., Su,L.J., Hong,Y.R., Cheng,T.S., Lee,Y.C.,
Lin,W.J., Still,I.H. and Huang,C.Y.
TITLE Identification of the substrates and interaction proteins of aurora
kinases from a protein-protein interaction model
JOURNAL Mol. Cell Proteomics 3 (1), 93-104 (2004)
PUBMED 14602875
REFERENCE 7 (bases 1 to 1843)
AUTHORS DeLuca,J.G., Howell,B.J., Canman,J.C., Hickey,J.M., Fang,G. and
Salmon,E.D.
TITLE Nuf2 and Hec1 are required for retention of the checkpoint proteins
Mad1 and Mad2 to kinetochores
JOURNAL Curr. Biol. 13 (23), 2103-2109 (2003)
PUBMED 14654001
REFERENCE 8 (bases 1 to 1843)
AUTHORS DeLuca,J.G., Moree,B., Hickey,J.M., Kilmartin,J.V. and Salmon,E.D.
TITLE hNuf2 inhibition blocks stable kinetochore-microtubule attachment
and induces mitotic cell death in HeLa cells
JOURNAL J. Cell Biol. 159 (4), 549-555 (2002)
PUBMED 12438418
REMARK GeneRIF: Data highlight a specific role for hNuf2 in
kinetochore-microtubule attachment and suggest that hNuf2 is part
of a molecular linker between the kinetochore attachment site and
tubulin subunits within the lattice of attached plus ends.
REFERENCE 9 (bases 1 to 1843)
AUTHORS Nabetani,A., Koujin,T., Tsutsumi,C., Haraguchi,T. and Hiraoka,Y.
TITLE A conserved protein, Nuf2, is implicated in connecting the
centromere to the spindle during chromosome segregation: a link
between the kinetochore function and the spindle checkpoint
JOURNAL Chromosoma 110 (5), 322-334 (2001)
PUBMED 11685532
REFERENCE 10 (bases 1 to 1843)
AUTHORS Wigge,P.A. and Kilmartin,J.V.
TITLE The Ndc80p complex from Saccharomyces cerevisiae contains conserved
centromere components and has a function in chromosome segregation
JOURNAL J. Cell Biol. 152 (2), 349-360 (2001)
PUBMED 11266451
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AL592435.2 and BC008489.1.
On Nov 15, 2006 this sequence version replaced gi:22027505.
Summary: This gene encodes a protein that is highly similar to
yeast Nuf2, a component of a conserved protein complex associated
with the centromere. Yeast Nuf2 disappears from the centromere
during meiotic prophase when centromeres lose their connection to
the spindle pole body, and plays a regulatory role in chromosome
segregation. The encoded protein is found to be associated with
centromeres of mitotic HeLa cells, which suggests that this protein
is a functional homolog of yeast Nuf2. Alternatively spliced
transcript variants that encode the same protein have been
described. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (2) differs in the 5' UTR compared
to variant 1. Variants 1 and 2 encode the same protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF326731.1, BC008489.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025085, ERS025088 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-67 AL592435.2 66418-66484
68-1835 BC008489.1 1-1768
1836-1843 AL592435.2 100241-100248
FEATURES Location/Qualifiers
source 1..1843
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q23.3"
gene 1..1843
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/note="NUF2, NDC80 kinetochore complex component"
/db_xref="GeneID:83540"
/db_xref="HGNC:14621"
/db_xref="MIM:611772"
exon 1..134
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 27
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:189794484"
variation 125
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:11557392"
exon 135..277
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
misc_feature 137..139
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/note="upstream in-frame stop codon"
variation 148
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="g"
/replace="t"
/db_xref="dbSNP:372718799"
CDS 155..1549
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/note="cancer/testis antigen 106; cell division cycle
associated 1; hNuf2; hNuf2R; hsNuf2; cell division
cycle-associated protein 1; NUF2, NDC80 kinetochore
complex component, homolog"
/codon_start=1
/product="kinetochore protein Nuf2"
/protein_id="NP_113611.2"
/db_xref="GI:117968353"
/db_xref="CCDS:CCDS1245.1"
/db_xref="GeneID:83540"
/db_xref="HGNC:14621"
/db_xref="MIM:611772"
/translation="
METLSFPRYNVAEIVIHIRNKILTGADGKNLTKNDLYPNPKPEVLHMIYMRALQIVYGIRLEHFYMMPVNSEVMYPHLMEGFLPFSNLVTHLDSFLPICRVNDFETADILCPKAKRTSRFLSGIINFIHFREACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKESLNLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFKMST
"
misc_feature 155..1309
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZD4.2);
Region: Interaction with the N-terminus of NDC80"
misc_feature 155..598
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/note="Nuf2 family; Region: Nuf2; pfam03800"
/db_xref="CDD:190755"
misc_feature 893..895
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 1310..1546
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9BZD4.2);
Region: Interaction with the C-terminus of NDC80 and the
SPBC24-SPBC25 subcomplex"
variation 187
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="t"
/db_xref="dbSNP:138555791"
variation 196
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="t"
/db_xref="dbSNP:201923428"
variation 247
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:201426055"
variation 255
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="t"
/db_xref="dbSNP:148475750"
exon 278..352
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 320
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="g"
/db_xref="dbSNP:142683655"
variation 322
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="c"
/db_xref="dbSNP:16852612"
exon 353..429
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 372
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:149980165"
variation 412
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:113602684"
variation 419
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:369269006"
exon 430..491
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 453
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:368618280"
variation 469
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="g"
/db_xref="dbSNP:371954652"
variation 476
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="g"
/replace="t"
/db_xref="dbSNP:142612141"
variation 484
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:374014113"
exon 492..589
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 501
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:201079271"
variation 524
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:369351164"
variation 545
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:147917145"
variation 553
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:141744491"
variation 557
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:373198630"
variation 558
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:201463150"
variation 565
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:148215962"
variation 571
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:369947700"
variation 589
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:142235785"
exon 590..663
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 600
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:139996430"
variation 622
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:144568103"
variation 625
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:34426463"
variation 626
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747498"
variation 640
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:377474776"
variation 663
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="t"
/db_xref="dbSNP:192013645"
exon 664..760
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 675
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:141893601"
variation 681
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="t"
/db_xref="dbSNP:373453967"
variation 683
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:376561383"
variation 712
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="t"
/db_xref="dbSNP:1509022"
variation 721
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:201197914"
variation 726
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:143503582"
variation 736
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:370651448"
variation 750
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="c"
/db_xref="dbSNP:374285371"
variation 759
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:144627000"
exon 761..823
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 819
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:138752079"
exon 824..961
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 832
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:200859782"
variation 838
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="g"
/replace="t"
/db_xref="dbSNP:375949382"
variation 840
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:11802875"
variation 858
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="c"
/db_xref="dbSNP:199499282"
variation 869
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="c"
/db_xref="dbSNP:16852767"
variation 925
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:113544263"
variation 936
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="c"
/db_xref="dbSNP:149575845"
variation 961
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="t"
/db_xref="dbSNP:372189646"
exon 962..1102
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 982
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:200015425"
variation 1037
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:201922994"
variation 1089
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:375668189"
variation 1093
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="g"
/db_xref="dbSNP:148952696"
exon 1103..1278
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 1120
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:149167689"
variation 1138
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="g"
/db_xref="dbSNP:188255733"
variation 1174
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="g"
/replace="t"
/db_xref="dbSNP:377218991"
variation 1175
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:374182596"
variation 1179
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:140857251"
variation 1194
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:113047814"
variation 1240
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:147464307"
variation 1264
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:201201382"
variation 1265
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:199764107"
exon 1279..1414
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 1322
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:375173490"
variation 1323
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:116669228"
variation 1343
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:201334528"
variation 1372
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:368896054"
variation 1376
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:372459343"
variation 1391
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="g"
/db_xref="dbSNP:377021975"
variation 1393
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:200200000"
exon 1415..1843
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/inference="alignment:Splign:1.39.8"
variation 1429
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:141046135"
variation 1447
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="g"
/db_xref="dbSNP:146451154"
variation 1460
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:144589776"
variation 1483
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="c"
/replace="t"
/db_xref="dbSNP:369149355"
variation 1536
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:372961469"
variation 1549
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:376734738"
variation 1556
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:367996407"
variation 1568
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="g"
/replace="t"
/db_xref="dbSNP:372378750"
variation 1745
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:189726032"
variation 1757
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
/replace="a"
/replace="g"
/db_xref="dbSNP:180849873"
polyA_site 1838
/gene="NUF2"
/gene_synonym="CDCA1; CT106; NUF2R"
ORIGIN
gcggaatggggcgggacttccagtaggaggcggcaagtttgaaaagtgatgacggttgacgtttgctgatttttgactttgcttgtagctgctccccgaactcgccgtcttcctgtcggcggccggcactgtagattaacaggaaacttccaagatggaaactttgtctttccccagatataatgtagctgagattgtgattcatattcgcaataagatcttaacaggagctgatggtaaaaacctcaccaagaatgatctttatccaaatccaaagcctgaagtcttgcacatgatctacatgagagccttacaaatagtatatggaattcgactggaacatttttacatgatgccagtgaactctgaagtcatgtatccacatttaatggaaggcttcttaccattcagcaatttagttactcatctggactcatttttgcctatctgccgggtgaatgactttgagactgctgatattctatgtccaaaagcaaaacggacaagtcggtttttaagtggcattatcaactttattcacttcagagaagcatgccgtgaaacgtatatggaatttctttggcaatataaatcctctgcggacaaaatgcaacagttaaacgccgcacaccaggaggcattaatgaaactggagagacttgattctgttccagttgaagagcaagaagagttcaagcagctttcagatggaattcaggagctacaacaatcactaaatcaggattttcatcaaaaaacgatagtgctgcaagagggaaattcccaaaagaagtcaaatatttcagagaaaaccaagcgtttgaatgaactaaaattgtcggtggtttctttgaaagaaatacaagagagtttgaaaacaaaaattgtggattctccagagaagttaaagaattataaagaaaaaatgaaagatacggtccagaagcttaaaaatgccagacaagaagtggtggagaaatatgaaatctatggagactcagttgactgcctgccttcatgtcagttggaagtgcagttatatcaaaagaaaatacaggacctttcagataatagggaaaaattagccagtatcttaaaggagagcctgaacttggaggaccaaattgagagtgatgagtcagaactgaagaaattgaagactgaagaaaattcgttcaaaagactgatgattgtgaagaaggaaaaacttgccacagcacaattcaaaataaataagaagcatgaagatgttaagcaatacaaacgcacagtaattgaggattgcaataaagttcaagaaaaaagaggtgctgtctatgaacgagtaaccacaattaatcaagaaatccaaaaaattaaacttggaattcaacaactaaaagatgctgctgaaagggagaaactgaagtcccaggaaatatttctaaacttgaaaactgctttggagaaataccacgacggtattgaaaaggcagcagaggactcctatgctaagatagatgagaagacagctgaactgaagaggaagatgttcaaaatgtcaacctgattaacaaaattacatgtctttttgtaaatggcttgccatcttttaattttctatttagaaagaaaagttgaagcgaatggaagtatcagaagtaccaaataatgttggcttcatcagtttttatacactctcataagtagttaataagatgaatttaatgtaggcttttattaatttataattaaaataacttgtgcagctattcatgtctctactctgccccttgttgtaaatagtttgagtaaaacaaaactagttacctttgaaatatatatatttttttctgttactatc
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:83540 -> Molecular function: GO:0003674 [molecular_function] evidence: ND
GeneID:83540 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:83540 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
GeneID:83540 -> Biological process: GO:0007059 [chromosome segregation] evidence: NAS
GeneID:83540 -> Biological process: GO:0007067 [mitosis] evidence: IEA
GeneID:83540 -> Biological process: GO:0051301 [cell division] evidence: IEA
GeneID:83540 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: NAS
GeneID:83540 -> Cellular component: GO:0000777 [condensed chromosome kinetochore] evidence: IEA
GeneID:83540 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
GeneID:83540 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:83540 -> Cellular component: GO:0031262 [Ndc80 complex] evidence: IDA
by
@meso_cacase at
DBCLS
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